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EMBL News archive

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10 September 2024 A brain section is seen in the background, from which a 'highway'emerges, with lit up neurons spaced like cars on the highway.

Follow the cellular road

Science & Technology An AI-enhanced advanced microscopy approach offers promise in better understanding glioblastomas, one of the deadliest brain cancers.

2024

science-technology

5 September 2024 Male scientist standing in front of a set of stairs.

Promoting impact-driven science

People & Perspectives PROMETHEUS is an EMBL-born grassroots initiative to promote and optimise impact-driven science.

2024

people-perspectives

4 September 2024

What I’ve learned: Alvis Brazma

People & Perspectives EMBL-EBI alumnus Alvis Brazma reflects on how mathematics and mountaineering have shaped his life and why keeping things simple in bioinformatics is key.

2024

people-perspectivesperspectives

30 August 2024 A multi-coloured donut representing the structure of an NPC.

“Structurally” sound

Science & Technology The function of biological molecules is intimately linked to their structure. In the 50 years since EMBL was established, its researchers and engineers have constantly provided leadership in structural biology research and services, resulting in many scientific breakthroughs and novel insights.

2024

science-technology

27 August 2024 In the foreground is a photoacoustic dye from the red end of the visible spectrum that is ‘turned on’. It produces an ultrasound emission that can be detected and measured. A dye that is ‘turned off’ is shown in the left background.

Seeing into the depths

Science & Technology EMBL scientists applied molecular engineering to build photoacoustic probes to label and visualise neurons deep within brain tissue.

2024

science-technology

23 August 2024

Welcome: David Ocaña

People & Perspectives EMBL-EBI’s new Head of Applications will use his expertise in cloud infrastructure and security to support the institute’s open data resources.

2024

people-perspectivesperspectives

21 August 2024 Three images of the cell at different stages of mitosis. In the left: round navy shape and irregular thick magenta line within it. In the middle: the same round shape with two irregular magenta shapes. On the right: Two round navy shapes connected with each other. Each of them holds shiny magenta-yellow clusters.

The forces behind chromosome repulsion and attraction during cell division

Science & Technology EMBL Heidelberg researchers discovered how a protein switches between repelling and gluing chromosomes during cell division. This helps the mother cell to divide the genome equally into two daughter cells and cluster chromosomes inside the daughter nuclei, ensuring a successful cell division.

2024

science-technology

16 August 2024 Two trucks with EMBL and TREC logos drive along a road next to the seaside, in the background are hills and houses from the suburbs of Athens.

TREC expedition concludes sampling in Greece

Connections The TREC expedition concluded its sampling in Greece and strengthened scientific exchange and collaborative networks with their Greek partners during a political and scientific stakeholder event in Athens.

2024

connections

14 August 2024

Merging passion, collaboration, and serendipity

People & Perspectives EMBL alumnus Thibaut Brunet, recipient of the 2024 John Kendrew Young Scientist Award, shares his scientific journey – from a childhood passion for nature to the discovery of a new species of choanoflagellate.

2024

people-perspectives

1 August 2024 Open Targets logo

Why clinical trials stop: the role of genetics

Science & Technology Using machine learning to analyse the genetic factors behind early clinical trial termination, researchers find a link between genetic evidence and trial outcome.

2024

research-highlightsscience-technology

31 July 2024 Silhouette of gastrointestinal track alongside an illustrator's representation of the carcinogens and antibiotics that seem to be affected by the gut microbiome

Gut microbes implicated in bladder cancer

Science & Technology Study shows that gut bacteria can metabolise carcinogens and cause them to accumulate in distant organs, leading to tumour development.

2024

science-technology

25 July 2024 Colourful arts and craft projects on a table

Science City Day at EMBL Hamburg

Lab Matters A major public engagement event at EMBL Hamburg attracted thousands. A video captures the spirit of the day from participants.

2024

lab-matters

24 July 2024

Sparking the next 50 years of collaborative discovery

Connections EMBL's 50th anniversary symposium brought together its vibrant community, showcased its many scientific contributions, and drove discussion on the future of Europe's leading life sciences laboratory.

2024

connections

10 July 2024

Leveraging expertise across EMBL services

Connections A scientific workshop on flow cytometry was organised at EMBL Rome, taking advantage of the presence of the Advanced Mobile Laboratory, the biggest unit of EMBL’s mobile lab fleet.

2024

connections

8 July 2024

EMBL Annual Report 2023 now online

EMBL Announcements EMBL’s 2023 Annual Report has been published, sharing achievements in its various missions, plus facts & figures from the year.

2024

embl-announcements

2 July 2024

Bulgaria becomes EMBL prospect member state

EMBL Announcements Bulgaria has become the latest EMBL prospect member state, starting a three-year process toward full membership. The prospect membership opens up new opportunities for mutual exchange and collaboration. Including Bulgaria, EMBL is now supported by 29 full member states, one associate member state,…

2024

embl-announcements

2 July 2024

IIT-EMBL: New molecules to modulate gene expression

Science & Technology A new research paper published in Nature Communications lays the groundwork for the development of new drugs specific to genetic mutations or alterations responsible for the onset of tumours or genetic diseases.

2024

science-technology

1 July 2024

EMBL celebrates 50 years of cutting-edge life science research

EMBL Announcements EMBL celebrates 50 years of cutting-edge European research: founded in Heidelberg by the first ten member states, Europe's pioneering Molecular Biology Laboratory (EMBL) is now supported by 29 member states and stands for outstanding open research, scientific services for researchers, innovative…

2024

embl-announcements

27 June 2024

Exploring microbial life in context

Science & Technology EMBL researchers and their partners have been studying microbial functions and interactions for the benefit of human and planetary health for the last two decades.

2024

science-technology

25 June 2024 In the front, a 3D model of three molecules bound together: METTL6 in (orange), serine tRNA synthetase in (shades of lilac) and serine tRNA (black). In the background an illustration of a construction site. Two trucks with ‘UGA’ and ‘AGA’ written on them are visible at the bottom.

An enzyme with a smart friend

Science & Technology EMBL Grenoble’s Kowalinski Group analysed the structure of an enzyme responsible for modifying tRNA molecules to fine-tune protein production. They discovered that to distinguish almost identical, yet different, tRNA molecules, the enzyme uses help from another enzyme – a type of cooperation…

2024

science-technology

21 June 2024

Welcome: Mallory Freeberg

People & Perspectives The new Team Leader for Human Genomics at EMBL-EBI shares how curiosity and maths shaped her career and what it takes to be a community builder.

2024

people-perspectivesperspectives

19 June 2024 In the centre: green angular origami-like shapes stacked on top of each other. Small orange rectangles akin to adhesive tape are placed where the green shapes connect with each other. In the background: a circle in the middle and cancer cells on the left and right.

‘Invisible’ protein keeps cancer at bay

Science & Technology EMBL Hamburg scientists and collaborators discovered a new molecular mechanism in which an unstructured protein disables one of the main cancer-promoting proteins by gluing them into an elongated stack. Data from human patient samples support the role of this mechanism in prostate cancer…

2024

science-technology

18 June 2024 A progression of three images against a blue/purple background. Each image shows a simulated mouse embryo inner cell mass with two types of cells marked in pink and green respectively. From the first to the third image, the pink cells slowly move from the outer edge to the inside of the mass.

Minecraft-ing our way into studying cell sorting

Science & Technology A theoretical model involving tiny Minecraft-like cubes can help us understand dynamic biological processes, such as cell sorting in embryos.

2024

science-technology

17 June 2024

TREC in Italy – sampling from coast to coast

Connections For almost two months, Italy was the stage for the TREC expedition, with a rich programme of events organised across the country attended by the public, scientists, schools, and high-level political stakeholders, including Minister of University and Research Anna Maria Bernini.

2024

connections

12 June 2024 A coffee mug on a table, with photographs nearby. The photos show pictures from the 1970s and 1980s, with a football team and a scientific research team represented.

Looking back: EMBL in the 1970s and 1980s

Lab Matters A special Coffee with EMBL session celebrated EMBL’s 50th anniversary by inviting alumni to reflect on the organisation’s first two decades.

2024

lab-matters

12 June 2024

AI approaches in structural biology and drug discovery

Connections EMBL Grenoble and the ESRF hosted a workshop bringing together representatives from research and industry to discuss the ever-growing role of artificial intelligence in the field of structural biology.

2024

connections

6 June 2024 A schematic of transport of dipeptides (white sticks) by the GLMP–MFSD1 complex. The transporter undergoes the common alternating access mechanism transitioning from outward-open conformation after dipeptide binding in the lysosomal lumen, to the occluded state where both sides of the binding site are closed, to the inward-open conformation enabling dipeptide release to the cytoplasm.

Structure and function of new lysosome transporter revealed

Science & Technology The group of Christian Löw at EMBL Hamburg and CSSB, and collaborators from the Christian-Albrechts-University Kiel and CNRS & Université Paris Cité worked together to reveal the structure and function of a previously unknown lysosome transporter, MFSD1.

2024

science-technology

29 May 2024 Two scientists stand in front of window, talking

12 moments of philanthropy: #5 Friends of EMBL

Connections Starting in 2014, Friends of EMBL engages a diverse range of individuals to support and connect with EMBL research. Through unique events and philanthropic contributions, members play a vital role in fostering a stronger bond between EMBL and society.

2024

connections

28 May 2024 An illustration of cells in a mosaic context, demonstrating the idea of genetic mosaicism in blood stem cells.

Genetic mosaicism more common than thought

Science & Technology Blood stem cells from healthy people carry major chromosomal alterations, a study in Nature Genetics by researchers at the Max Delbrück Center and the European Molecular Biology Laboratory (EMBL) finds. The discovery suggests that we are all genetic mosaics, which may contribute to ageing-related…

2024

science-technology

24 May 2024

Stephen Cusack: what I’ve learned

People & Perspectives Stephen Cusack, world-renowned structural biologist and former Head of EMBL Grenoble, reflects on his early influences, his achievements, and the lessons he’s learned as he embarks on his next adventure

2024

people-perspectives

22 May 2024 A sphere with two separated halves; the left half is blue and depicts chromosomes separating along spindles inside multiple nuclei, while the right half is orange, depicting a single set of chromosomes and a spindle with no nuclear envelope visible.

Exploring diversity in cell division

Science & Technology New research by EMBL scientists shows how different modes of cell division used by animals and fungi might have evolved to support diverse life cycles.

2024

science-technology

16 May 2024

Welcome: Julio Saez-Rodriguez

People & Perspectives EMBL-EBI's new Head of Research shares his plans and priorities.

2024

people-perspectivesperspectives

14 May 2024

Toby Gibson: what I’ve learned

People & Perspectives Toby Gibson reflects on 38 years at EMBL, the scientific tools he built along the way, and the state of science today.

2024

people-perspectives

9 May 2024

An epigenome editing toolkit to dissect the mechanisms of gene regulation

Science & Technology A study from the Hackett group at EMBL Rome led to the development of an epigenetic editing system that allows to precisely program chromatin modifications at any specific position in the genome, to understand their causal role in transcription regulation.

2024

science-technology

1 May 2024 Alt Text: An artistic representation of gut microbes and sperm cells

Father’s gut microbes affect the next generation

Science & Technology Scientists from EMBL Rome and EMBL Heidelberg found that disrupting the gut microbiome of male mice increases the risk of disease in their offspring. Their findings suggest that a father’s pre-conception environment can have lifelong effects on offspring.

2024

science-technology

30 April 2024 Colourful vertical panels each show different microscopic images possible with the high-tech tools in EMBL's Imaging Centre

12 moments of philanthropy: #4 EMBL Imaging Centre

Connections A bold vision to build a centre of excellence for imaging captured the imagination and support from private and public donors to help create the EMBL Imaging Centre.

2024

connections

30 April 2024 Open Targets logo

MSD joins the Open Targets consortium

EMBL Announcements MSD joins as the latest partner in the Open Targets consortium, enhancing the initiative’s collaborative efforts in drug discovery.

2024

announcementsembl-announcements

23 April 2024 This image showcases a processor with neon lights and abstract shapes that represent the flow and integration of spatial omics information. The background shows the analyzed and annotated breast cancer sample.

A universal framework for spatial biology

Science & Technology SpatialData is a tool developed by EMBL scientists in cooperation with multiple research institutions to unify and integrate data from different omics technologies in a spatial environment, providing holistic insights into health and disease. Researchers can now freely access and use SpatialData…

2024

science-technology

22 April 2024 A woman is looking through a book and checking a microscopy image on the screen of a laptop in front of her. On her left, there is the Curiosity microscope, which consists of grey, blue and yellow blocks connected with a red stripe.

Sparking curiosity: the Curiosity microscope

Lab Matters BIOcean5D is an EMBL-coordinated project co-funded by the European Union that unites 31 institutes to address pressing global challenges on marine biodiversity.

2024

lab-matters

18 April 2024 Group picture with a truck-size laboratory on wheels in the background

TREC sets off along the Mediterranean coast

Connections The second phase of the TREC expedition focuses on the Mediterranean coast, with Barcelona, Spain, hosting the first ‘superstop’ of 2024

2024

connections

8 April 2024 Artist’s stylised, semi-abstract representation of artificial intelligence

When AI meets biology

Science & Technology A recent EMBO | EMBL conference provided a forum for researchers to share how AI is making a difference in biology and bioinformatics.

2024

science-technology

4 April 2024

Building the cell’s splicing machine

Science & Technology New study from the Galej group provides deeper structural insight into the assembly of a critical molecular machine, that removes non-coding information from genes during their expression.

2024

science-technology

20 March 2024 4 people are standing in front of a man, Vladimir Benes, who speaks to them

Connecting shores and exploring new avenues for collaboration with Malta

Connections During a visit from high-level representatives of EMBL’s member state Malta, the honourable delegation allowed a peek behind the scenes of their scientific and institutional collaborations, and shared their memories and future aspirations for the partnership.

2024

connectionsevents

11 March 2024 Casting new light on gene regulation in development

Casting new light on gene regulation in development

Science & Technology New research from EMBL Heidelberg shows how cells in developing embryos undergo a major shift in the way they regulate gene expression as they mature and differentiate.

2024

sciencescience-technology

8 March 2024 Collage of six images showing scientists and science professionals during the TREC expedition, with a banner saying “International Women’s Day 2024” and the TREC expedition logo.

Insights and wisdom from the women of TREC

Lab MattersPeople & Perspectives On International Women’s Day 2024, we hear from some of the women who have been working tirelessly in the field and behind the scenes as part of the Traversing European Coastlines (TREC) expedition.

2024

lab-matterspeople-perspectives

6 March 2024 The background shows a render of a suspension of tumour cells, while an inset shows the structures of two proteins – MAGEA4 and RAD18 – marked in green and blue respectively

Studying the relationship between cancer-promoting proteins

Science & Technology A new study from the Bhogaraju Group at EMBL Grenoble reveals how the cancer-promoting MAGE family of proteins bind to their targets, aiding the development of anti-cancer drugs that target these proteins.

2024

sciencescience-technology

1 March 2024 Photographs of two male scientists in round insets against a decorative background

2024 EMBL Alumni Award recipients announced

EMBL Announcements Two former EMBL scientists have been recognised for their outstanding contributions to research and leadership capabilities in the fields of evolutionary cell biology and molecular medicine.

2024

alumniembl-announcements

19 February 2024 Collage of nine pictures with seven photographs showing expedition members sampling and engaging in public outreach activities, and two photos showing EMBL’s new mobile labs.

TREC in 2024: bringing it home

Science & Technology The Traversing European Coastlines (TREC) expedition prepares to begin its next phase of sampling, with stops in Spain, Greece, Italy, and beyond.

2024

sciencescience-technology

12 February 2024 Female scientist stands in front of white shelves filled with vials of fruit flies

Anne Ephrussi: what I’ve learned

Lab MattersPeople & Perspectives After 32 years at EMBL – leading a developmental biology research group and later simultaneously serving as EMBL’s Dean for its PhD programme, Anne Ephrussi has retired, ready to start her life’s next chapter.

2024

lab-matterspeople-perspectives

1 February 2024

We are EMBL: Renato Alves on Bio-IT and stargazing

Lab MattersPeople & Perspectives Renato Alves talks about his time at EMBL, the Bio-IT project, his wishes for EMBL in its anniversary year, and how a passion for night hikes and stargazing led to the creation of EMBL’s astronomy club.

2024

lab-matterspeople-perspectives

29 January 2024 Man leaning against a wall

Welcome: Kyle Morris

Lab MattersPeople & Perspectives Kyle Morris joins EMBL-EBI as Electron Microscopy Data Bank (EMDB) Team Leader.

2024

lab-matterspeople-perspectives

25 January 2024 An oval light blue shape. In the central part, there is a smaller a red object, from which stem many highly branched smaller canals that cover a significant part of the blue surface. The whole sponge image is in placed in a circle. The background around the circle is blue-green.

Ancient ‘relaxant-inflammatory’ response gets sponges moving

Science & Technology Sponges lack muscles and neurons. Yet, they make coordinated movements. Scientists at EMBL Heidelberg have discovered that sponge movement is controlled by an ancient ‘relaxant-inflammatory’ response that is also present in vertebrate blood vessels. The findings shed light on sponge physiology…

2024

sciencescience-technology

23 January 2024 Collage of EMBL historical photos with a 50-year anniversary logo

Reflections for the future during EMBL’s 50th anniversary year

Lab MattersPeople & Perspectives EMBL’s link to other sciences and its tradition of collaborative discovery carry on, providing the model and means to address big challenges, including climate change and biodiversity loss.

2024

lab-matterspeople-perspectives

9 January 2024 Latvian flag comprised of deep red with a horizontal white stripe across the center

Latvia becomes EMBL’s 29th member state

EMBL AnnouncementsLab Matters Latvia’s life sciences sector will benefit from expanded access to the leading European research, services, and training provided by EMBL.

2024

embl-announcementslab-matters

21 December 2023 On the left: image of a protein complex in a shape of a yellow doughnut with blue elements. Above it is a drawing of nucleic acid with arrows connecting nitrogenous bases to different points in the protein complex. On the right: a line with peaks indicating the peaks recorded in mass spectrometry. Above two peaks, there are smaller depictions of the doughnut-shaped complex, one with a blue element and one without.

RNA to rule them all

Science & Technology The Kosinski Group at EMBL Hamburg collaborated with other groups in Hamburg to reveal critical steps in Lassa virus ribonucleoparticle assembly and recruitment, and the crucial role played by RNA in in the Lassa virus life cycle.

2023

sciencescience-technology

19 December 2023 Cartoon showing nanoparticles on a conveyer belt passing through a machine. They are ordered by size and the smallest one pass through the machine before the bigger ones. A ray of light enters the machine, where a nanoparticle is being scanned, and leaves it on the other side. A monitor on top of the scanning machine shows an X-ray of a nanoparticle.

‘X-ray vision’ for investigation of mRNA nanomedicines

Science & Technology EMBL Hamburg, Johannes Gutenberg University Mainz, Postnova Analytics GmbH, and BioNTech SE have developed a new method to quantitatively investigate sizes of nanoparticles containing mRNA. It may become an important part of regular characterisation of mRNA nanomedicines in the future.

2023

sciencescience-technology

14 December 2023 Photo of Selina Storm standing in front of the PETRA III synchrotron storage ring.

We are EMBL: Selina Storm on PETRA IV and new perspectives for EMBL Hamburg

Lab MattersPeople & Perspectives EMBL Hamburg is located at the PETRA III synchrotron, which in the future, will be upgraded to PETRA IV. Selina Storm is theEMBL@PETRA IV Programme Manager. Here, she speaks about her role and the benefits of PETRA IV for EMBL.

2023

lab-matterspeople-perspectives

7 December 2023 Against blue and green background are two faux polaroids, one of an older man holding a coffee cup and the other a man in glasses

Navigating success: an EMBL alumni mentorship story

Lab Matters A recent success story of the Alumni Mentorship Programme is that of Luis Pedro Coelho, a Portuguese former postdoctoral fellow in the Bork Group, and his mentor Frank Gannon, former EMBO Director and EMBL Group Leader and Senior Scientist.

2023

alumnilab-matters

27 November 2023 A man and a woman looking at the camera, parts of a restaurant are visible in the background.

Exploring the universe: Roel Wijnaendts

People & Perspectives EMBL alumnus Roel Wijnaendts looks back at a long career in academic research and entrepreneurship that has left an indelible mark in the fields of instrumentation and optics.

2023

alumnipeople-perspectives

27 November 2023 Photo of two people brainstorming at the table covered with several papers and images related to the research project, such as the structure of the molecule, a map with the Solar Lake marked, photo of EMBL Hamburg, photo of Garo Antranikian looking into a microscope, pages of the manuscript, data graphs, and more.

Hamburg collaboration paves the way to cleaner technologies for industry

Science & Technology An interdisciplinary collaboration between Hamburg scientists has yielded new insights into the structure and function of a heat-resistant enzyme from an exotic microbe. In this interview, EMBL Hamburg’s Matthias Wilmanns and TUHH’s Garo Antranikian discuss how their collaboration developed and…

2023

sciencescience-technology

23 November 2023 Photographs of two scientists on a decorative background

ERC Consolidator Grants awarded to two EMBL researchers

EMBL AnnouncementsLab Matters Alba Diz-Muñoz and Arnaud Krebs from EMBL Heidelberg have received grants to work on projects that aim, respectively, to understand the cellular mechanics that control cell division and investigate the regulatory networks that govern transcription factor function.

2023

embl-announcementslab-matters

22 November 2023 Oliver Stegle passionately drawing work-related content with a green pen on a whiteboard. On the whiteboard, there are coordinates and equations, such as “n=2”.

How AI shapes the life sciences: an interview with Oliver Stegle

Lab MattersPeople & Perspectives EMBL scientist Oliver Stegle explains how AI-based tools have the potential to transform our ability to better understand the complexity of life and how these tools will shape the future of life science exploration.

2023

lab-matterspeople-perspectives

17 November 2023

TREC – Towards the end of the first phase

ConnectionsLab Matters The TREC expedition has come to the end of its first phase. The last superstop of 2023 was hosted by CIIMAR in Porto and, despite the adverse weather conditions, included many scientific and public engagement activities.

2023

connectionslab-matters

16 November 2023

EMBLetc. issue 101 published

EMBL AnnouncementsLab Matters The newest issue of our online magazine dives deep into a critical research direction in developmental biology, structures of promiscuous proteins, EMBL’s newest service offerings in field research, and much, much more.

2023

embl-announcementslab-matters

16 November 2023

New evidence on retinal function

Science & Technology A new study from the Asari group at EMBL Rome shows a different retinal function in awake mice compared to isolated retinal samples. These new insights could help to develop prosthetic devices that can act as a retina in the future.

2023

sciencescience-technology

15 November 2023 Group picture with mountain in the background

Looking back on 20 years of structural biology collaboration in Grenoble

ConnectionsLab Matters On this date (15 November), 21 years ago, the EMBL, ESRF, ILL, and IBS directors signed a memorandum of understanding to create the Partnership for Structural Biology (PSB) on the European Photon and Neutron (EPN) science campus in Grenoble.

2023

connectionslab-matters

14 November 2023 Blue thumbprint-sized ovals cluster together on a black background with white and pink dots sporadically situated on the blue ovals.

Five takeaways from ‘Seeing is believing’ in 2023

Science & Technology A recent EMBO | EMBL symposium brought together leading developers of imaging methods with cutting-edge applications that illustrate how imaging can answer biological questions.

2023

eventsscience-technology

7 November 2023

EMBL in Spain: Molecules to Ecosystems

Connections EMBL in Spain 2023 was held in Bilbao on Friday 9 October, hosted at the Center for Cooperative Research in Biosciences (CIC bioGUNE).

2023

alumniconnections

7 November 2023

Enjoying a science day in Grenoble

ConnectionsLab Matters EMBL Grenoble was once again present for the science outreach event ‘Parvis des Sciences’ on Saturday 14 October 2023.

2023

connectionslab-matters

1 November 2023 Sihyun Sung is standing next to experimental equipment for time-resolved serial X-ray crystallography. The light in the room is pink.

We are EMBL: Sihyun Sung on time-resolved structural biology

Lab MattersPeople & Perspectives In this interview, Sihyun Sung, Postdoctoral Fellow at EMBL Hamburg, talks about making molecular movies with time-resolved serial X-ray crystallography, his sources of inspiration, and the value of forging deeper connections with friends and colleagues.

2023

lab-matterspeople-perspectives

31 October 2023

EMBL’s southern hemisphere connection

ConnectionsLab Matters Ian Smith, Chair of EMBL Australia´s Council, chats about the synergies between the organisations, opportunities for collaboration, and ideas for exciting new programmes arising out of a recent visit to EMBL Heidelberg.

2023

connectionslab-matters

27 October 2023 The image shows a uerine environment made of a jelly-like and transparent material, with a cylindrical 3D structure.

Spotlight: Creating an artificial uterus

Science & Technology EMBL researchers have created an engineered uterus that allows a closer look at a mouse embryo’s development and its interactions with the uterine environment.

2023

picture-of-the-weeksciencescience-technology

26 October 2023 Photographs of three scientists on a decorative blue background

EMBL scientists receive prestigious ERC Synergy Grants

EMBL Announcements Jan Kosinski, Julia Mahamid, and Georg Zeller have received grants to enable ambitious projects aimed at mapping the cellular protein synthesis machinery in context and understanding complex host-microbiome interactions, respectively.

2023

embl-announcementsscience

26 October 2023

A promising target to fight inflammatory bowel diseases

Science & Technology Researchers from the Cusack group at EMBL Grenoble provide structural insights on the XIAP/RIPK2 complex, a promising drug target to fight inflammatory bowel diseases.

2023

sciencescience-technology

20 October 2023 Abstract art shows waves of yellow and green punctuated by pipe-like shapes poking out of the waves.

Six symposium takeaways about human microbiome research

Science & Technology Here are six takeaways from a recent EMBO/EMBL symposium that brought together scientists to discuss the state of research involving the human microbiome and its connection to health and disease.

2023

eventsscience-technology

18 October 2023 Female scientist looks directly at the camera, wearing blue jacket and white top

EMBL’s second Kafatos Lecture this Friday

EMBL Announcements Elena Conti will discuss how cells control the life and death of mRNA molecules at the 2023 annual Kafatos Lecture on 20 October in Munich.

2023

alumniembl-announcements

17 October 2023 Pill icons representing different antibiotic classes are seen exerting their effects on a bacterium, whose cell wall, membrane, and protein synthesis machinery (two different classes) can be seen as potential targets. Curved lines connect the pills to each other, representing synergies in drug interactions. More bacteria can be seen in the background.

Fighting antimicrobial resistance with new drug combinations

Science & Technology In an extensive investigation, EMBL researchers have tested over 10,000 drug combinations against some of the leading pathogenic bacteria carrying antimicrobial resistance and causing mortality. 

2023

sciencescience-technology

13 October 2023 Scientific illustration showing various model organisms used to study developmental plasticity and a series of concentric circles representing adaptability of interactions.

Understanding developmental plasticity in time and space

Lab MattersScience & Technology A two-week practical course introduced participants to the intricacies of studying the dynamic interplay between organisms and their changing environment and how it impacts development and evolution.

2023

lab-mattersscience-technology

9 October 2023

A night to share the wonders of science 

Lab Matters EMBL Rome celebrated the European Researchers’ Night by participating in an event organised at the CNR Campus in Montelibretti.

2023

lab-matters

6 October 2023

We are EMBL: Zuzana Koskova on her experience as a PhD student at EMBL Heidelberg

Lab MattersPeople & Perspectives Zuzana Koskova is a PhD student from Slovakia who, at the age of 19, left her country to pursue her career in biological sciences in Germany. In this interview, she talks about her interests, career aspirations, and recent participation at the Info Day held in Bratislava, where she had the…

2023

lab-matterspeople-perspectives

5 October 2023 A composite image of four 3D micrographs showing the cellular organelles of a phytoplankton marked in different colours.

Spotlight: Seeing into the seas

Science & Technology A new method developed by EMBL scientists can help us identify and investigate plankton species in field samples with greater speed, accuracy, and resolution than ever possible before.

2023

sciencescience-technology

2 October 2023 Outline of a human, purple against red background. Red RNA strand in the background, electrocardiogram across the image. On the right, outline of a Nobel prize medal.

mRNA nanomedicines scoop Nobel Prize in Physiology or Medicine

Science & Technology Pioneers of the mRNA nanomedicines technology receive 2023 Nobel Prize in Physiology or medicine. EMBL is pleased to have supported the development of the application of the mRNA nanomedicine technology through our long-standing collaboration with BioNTech, Johannes Gutenberg University Mainz and…

2023

sciencescience-technology

28 September 2023 Visual of AlphaFold Protein prediction, embedded into a visual of scientific data

EMBL receives German AI prize

EMBL Announcements EMBL receives the German AI prize awarded for outstanding services to the research and development as well as application and commercialisation of artificial intelligence (AI) in life science research.

2023

embl-announcementsscience

27 September 2023 A female scientist with shoulder-length hair and black shirt listens to a male scientist in burgundy shirt and white beard, seated to the right.

Five decades of EMBL visits

ConnectionsLab Matters Structural biologist Shlomo Trachtenberg has made research trips to EMBL from Israel since the late 1970s and reflects on the boost EMBL’s technology provided his research, the ingredients for an ideal research institution, and his ongoing fascination with microscopes.

2023

connectionslab-matters

21 September 2023

Understanding the mechanisms of enzyme catalysis

Science & Technology Enzymes constitute a large fraction of genomes – 20% in humans – which makes them a very important part of life. Despite decades of studies and a rich literature dedicated to understanding the reaction mechanisms of enzymes, the rules of enzyme catalysis are still not fully clear. A new…

2023

science-technologytechnology-and-innovation

21 September 2023 Group photo of the participants of the 12th annual meeting of the Nordic EMBL Partnership for Molecular Medicine in Espoo, Finland.

Forging collaborations across the Nordics

ConnectionsLab Matters The 12th annual meeting of the Nordic EMBL Partnership for Molecular Medicine took place in Espoo, Finland, between 11-14 September 2023.

2023

connectionslab-matters

21 September 2023 Man standing outside

Welcome: David Hulcoop

Lab MattersPeople & Perspectives David Hulcoop discusses how his experience bridging organisational cultures will help address critical challenges in drug discovery and target selection at Open Targets.

2023

announcementslab-matterspeople-perspectives

15 September 2023 Group of scientists attending symposium staring upward to the photographer.

Celebrating Stephen Cusack’s contributions to science

People & Perspectives Researchers from across the globe have gathered in Grenoble to celebrate the remarkable lifelong scientific achievements of Stephen Cusack, the former head of EMBL Grenoble.

2023

eventspeople-perspectives

15 September 2023

Switching off the cytokine storm

Science & Technology EMBL Grenoble and University of Geneva researchers shed light on the molecular activation of the MAP kinase p38α, the final ‘switch’ triggering the inflammatory response.

2023

sciencescience-technology

13 September 2023 Magenta and green sombrero-shaped object with grey lines beyond it sits against a black background

Understanding how cells avoid obstacles

Science & Technology EMBL researchers have identified a novel mechanism that allows cells to sense obstacles in their path and avoid them while navigating complex environments.

2023

sciencescience-technology

13 September 2023

Exploring Nexus Island

Lab Matters Learn more about the game-based workshop that lets participants experience what it feels like to be a researcher on the TREC expedition.

2023

lab-matters

8 September 2023 Female scientist looking into a microscope

TREC: Exploring the ocean’s oxygen supply

Lab MattersScience & Technology As part of the EMBL-led Traversing European Ecosystems (TREC) expedition, scientists are studying plankton to understand biodiversity, health, and our planet’s future.

2023

lab-mattersscience-technology

6 September 2023 A drawing of swordfish and a bubble containing a drawing of a molecular model. Both on blue background representing water.

Swordfish sword under X-rays: SAXS explained

Science & Technology Learn how scientists use bio-SAXS, an experimental X-ray technique, to study the shape and dynamics of proteins and other biomolecules. SAXS can be even used to analyse the structure of mineral particles in the swordfish sword bone, which can help scientists better understand bone ageing.

2023

sciencescience-technology

5 September 2023 Faces of Jordi van Gestel and Maria Zimmermann-Kogadeeva.

ERC starting grants for two EMBL Heidelberg researchers

EMBL AnnouncementsLab Matters Jordi van Gestel and Maria Zimmermann-Kogadeeva each receive 1.5 million EUR funding for research projects on microbial predators and the gut microbiome respectively

2023

embl-announcementslab-matters

31 August 2023 Part of a fruit fly embryo imaged against a dark background, with nuclei stained with DAPI (white), and a cluster of pole cells, marked by Vasa protein (yellow)

Spotlight: Off to the pole

Science & Technology For a fruit fly embryo to develop correctly, key factors need to get to the right place at the right time – a journey that starts in the developing egg, as seen in this image from the Ephrussi Group at EMBL Heidelberg

2023

picture-of-the-weeksciencescience-technology

24 August 2023 Set against a blue background, an illustration of a small paper shredder seemingly works at shredding mRNA, often in the form of origami shapes that float nearby.

Deciding when to destroy mRNA

Science & Technology Elena Conti will discuss how cells control the life and death of mRNA molecules at the next annual Kafatos Lecture on 20 October in Munich.

2023

alumniscience-technology

22 August 2023 Polaroid style shot of Sergiy Avilov, mentioning the years he was at EMBL

After EMBL: Sergiy Avilov

People & Perspectives Ukrainian scientist Sergiy Avilov uses the microscopy skills and scientific network he built at EMBL in his current role heading the Imaging Facility at the Max Planck Institute of Immunobiology and Epigenetics.

2023

alumnipeople-perspectives

18 August 2023 On green-hued multi-coloured background are four circle photographs of scientists working with high-tech equipment

Bringing scientific services together ‘2RISE’

Connections An upcoming EMBL-led infrastructure management training will help formalise information exchange in the Rhine-Neckar region to widen access to technology and scientific services for members of the Health + Life Science Alliance.

2023

connectionsevents

14 August 2023 Man standing in front of a building

Open data to power up the blue economy

People & Perspectives EMBL-EBI Senior Scientist Rob Finn explains why data coordination and sharing are fundamental for a sustainable blue economy.

2023

people-perspectivesperspectivesscience

8 August 2023 Clément Blanchet at the EMBL Hamburg’s P12 beamline’s experimental hutch.

Welcome: Clément Blanchet

Lab MattersPeople & Perspectives Clément Blanchet has been appointed to lead the team working on small-angle X-ray scattering (SAXS) at EMBL Hamburg. In this interview, he talks his ambitions for the future work of the SAXS Team, his passion for science, and a memorable ‘aha’ moment he had in his early career.

2023

lab-matterspeople-perspectives

3 August 2023 A male scientist working inside a trailer fitted with scientific instruments (left). On the right, the mobile lab trailer can be seen outside a large building in Sweden.

Bringing advanced life science technologies to the field

Lab MattersScience & Technology EMBL’s newly deployed Advanced Mobile Laboratory (AML) is bringing cutting-edge technologies to the European coast to help researchers study ‘life in context’.

2023

lab-mattersscience-technology

26 July 2023 Participants listen to the trainer in front of a screen displaying a microscopy image

Imaging-based spatial-omics: EMBO Practical Course at EMBL Rome 

Lab MattersScience & Technology The first EMBO Practical Course on imaging-based spatial-omics was organised at EMBL Rome to explore the latest techniques to visualise RNA transcripts and proteins in their native tissues.

2023

lab-mattersscience-technology

21 July 2023 Three-dimensional cartoon of the hexasome with a chromatin remodeler on DNA.

A glimpse into the hexasome: 40 years on

Science & Technology Research from the Eustermann group at EMBL Heidelberg reveals how the packaging of DNA into hexasomes impacts the function of enzymes involved in gene regulation.

2023

sciencescience-technology

10 July 2023 Green parasites on black background

Spotlight: Shedding light on deadly parasites

Lab MattersScience & Technology This single-celled organism the size of a dust particle is capable of causing deadly tropical diseases in both humans and livestock –Trypanosoma brucei, in an image by Luciano Dolce from EMBL.

2023

lab-matterspicture-of-the-weekscience-technology

7 July 2023 Cartoon of a molecule, formed by sticks and spheres.

Facilitating drug discovery against COVID-19

Science & Technology A collaboration between EMBL Grenoble and EBRIS scientists led to the characterisation of a new compound with promising activity against SARS-CoV-2 variants.

2023

sciencescience-technology

5 July 2023 Man standing in corridor

David Hulcoop appointed as Open Targets Director

EMBL Announcements Coming from a pharmaceutical industry background, David Hulcoop is set to take over as Executive Director of the public-private partnership Open Targets.

2023

announcementsembl-announcements

5 July 2023 Front page of annual report as shown on a tablet.

2022 EMBL Annual Report published

EMBL AnnouncementsLab Matters EMBL’s 2022 Annual Report is now available online, including a downloadable ‘Year in Review’.

2023

embl-announcementslab-matters

4 July 2023 Photos of the three scientists elected as EMBO members on green background.

EMBL scientists elected to EMBO Membership

Lab MattersPeople & Perspectives Three EMBL group leaders and six EMBL alumni were recognised for their contributions to the life sciences.

2023

lab-matterspeople-perspectives

4 July 2023 EMBL logo amended to note its upcoming 50th anniversary

Save the date: 4-5 July 2024!

EMBL Announcements EMBL will celebrate its 50th anniversary in 2024 with a dynamic scientific symposium. The event will share fundamental research that continues to open the way to scientific discoveries.

2023

embl-announcementsevents

3 July 2023 In the foreground: an intrinsically disordered protein, which has a form of a tangled, unstructured string. In the background: a set of parallel curved lines.

Bringing research on disordered proteins to order

Science & Technology A third of all known proteins are either completely or partially unstructured. EMBL scientists contributed to a new set of guidelines – Minimum Information About a Disorder Experiment (MIADE) – that will help researchers share data on unstructured proteins in a more useful way and will enable…

2023

sciencescience-technology

28 June 2023 Serbian flag

Serbia becomes EMBL prospect member

EMBL AnnouncementsLab Matters Starts three-year process toward full membership, opening up new opportunities for mutual exchange and collaboration.

2023

embl-announcementslab-matters

28 June 2023 Female scientist in white lab coat enjoying camaraderie of colleagues.

After EMBL: Urtė Neniškytė

People & Perspectives EMBL Rome alumna Urtė Neniškytė returned to her native Lithuania, helping establish the Vilnius University-EMBL Partnership Institute and advance genome-editing technologies there.

2023

alumnipeople-perspectives

26 June 2023

Connecting scientists, engaging citizens

ConnectionsLab Matters The TREC expedition stop in Sopot offered an opportunity to create connections with Polish scientists and citizens around the topics of planetary biology and ocean science.

2023

connectionslab-matters

22 June 2023 Woman stands in front of railing.

Welcome: Sihem Bennour

Lab MattersPeople & Perspectives Sihem Bennour, new head of HR, foresees a deeper culture of information sharing, listening, and problem solving with EMBL staff.

2023

lab-matterspeople-perspectives

13 June 2023 The conference brought together multiple disciplines from around the world to talk about life in context. Credit: EMBL creative team

An organisation and its environment

Science & Technology A recent EMBL conference brought together scientists from various disciplines to conjoin scientific pursuits studying ‘life in context’.

2023

eventsscience-technology

29 May 2023 group photo of the workshop participants

EMBL and SciLifeLab cooperate on data science

ConnectionsLab Matters The third meeting between EMBL and SciLifeLab communities took place in Uppsala and focused on data science, aiming at further expanding the collaboration

2023

connectionslab-matters

26 May 2023 Female scientist in white lab coat is showing material in a petri dish to EC official in lab coat

Sharing knowledge, widening access across Europe

ConnectionsLab Matters European Commission and EMBL renew commitment, agree on new areas of cooperation, in new EC DG’s first infrastructure visit since appointment.

2023

connectionslab-matters

25 May 2023 Close-up photo of a mother and father with their two young daughters

After EMBL: Heiko Runz and Laurence Ettwiller

People & Perspectives From biking together while at EMBL to assistant professorships at Heidelberg University, two academics soon formed a union that took them to the United States., into various industry positions, and now to a life with two young children.

2023

alumnipeople-perspectives

15 May 2023 Science illustration representing research on organoids, organs-on-chip and human health. The image shows an abstract composition of several elements referring to the tools and some areas of research covered at EMBL Barcelona, featured on the cover of the 100th issue of EMBL etc.

100th issue of EMBLetc. published

EMBL AnnouncementsLab Matters First published in 1999 as a black-and-white printed newsletter for EMBL staff and alumni, EMBLetc. has undergone many transformations in its 24 years of existence.

2023

embl-announcementslab-matters

11 May 2023 An colourful image taken from the World of Molecular Biology exhibition.

The World of Molecular Biology is open 

EMBL AnnouncementsLab Matters EMBL´s new permanent exhibition ‘The World of Molecular Biology’ in Heidelberg is now open for registration. The exhibition takes the visitor on a journey of scales, from genomes to ecosystems, and introduces key imaging technologies.

2023

embl-announcementslab-matters

10 May 2023 Globe with genome data from multiple people

A more diverse human reference genome

Science & Technology The human pangenome – one of the most complete collections of genome sequences released so far – captures rich human diversity.

2023

announcementssciencescience-technology

10 May 2023 Illustration showing a cute humanoid-shaped robot that spits pink droplets at a sheet.

Time-resolved crystallography for the masses

Science & Technology EMBL Hamburg scientists have contributed to the development of the Spitrobot, a ground-breaking experimental setup that will simplify creating molecular movies. The Spitrobot automates the sample preparation for time-resolved crystallography, which is used to create 3D snapshots of protein…

2023

sciencescience-technology

4 May 2023 Man stands in front of board listing corporate partner names

Vizgen joins EMBL science-industry programme

ConnectionsLab Matters Vizgen, the life science company dedicated to improving human health by visualising single-cell spatial genomics information, has joined EMBL’s Corporate Partnership Programme.

2023

connectionslab-matters

28 April 2023 two students wear virtual reality headsets

Building a broader European science community

ConnectionsLab Matters Croatian scientists and students from the Ruđer Bošković Institute and University of Zagreb visited EMBL to exchange ideas with researchers and public outreach experts on ways to increase interest, awareness, and involvement in science.

2023

connectionslab-matters

28 April 2023 Group photograph of people facing the camera holding certificates.

EMBL celebrates 43 new PhDs

Lab Matters On Friday 21 April 2023, EMBL held a graduation ceremony to celebrate its newest group of PhDs who graduated during the last 12 months. The graduating class comprised 43 fellows representing 17 nationalities and all six EMBL sites.

2023

eventslab-matters

20 April 2023 Photo of a human hand introducing a small element into a machine at the SPC Facility.

EMBL Hamburg joins northern European life science consortium

ConnectionsLab Matters EMBL Hamburg partners with the Hanseatic Life Science Research Infrastructure Consortium (HALRIC) to enhance life sciences research in Scandinavia and northern Germany. The consortium builds on the HALOS project to foster collaborations between industry, hospitals, and universities, leveraging…

2023

connectionslab-matters

20 April 2023 White woman with short red hair standing in garden in front of a tree. Picture of Angelika Thomasson. Credits: Marcos Lopez-Marrero/EMBL

We are EMBL: Angelika Thomasson on administrative support to EMBL staff

Lab MattersPeople & Perspectives Angelika Thomasson, administrative assistant at EMBL Grenoble, talks about her role in supporting her colleagues in organising events and travels, what she enjoys about EMBL, and which famous female scientist she would like to have coffee with.

2023

lab-matterspeople-perspectives

18 April 2023 Decorative image showing WormBase ParaSite logo

WormBase ParaSite 18 released

Science & Technology WormBase ParaSite release 18 adds largest number of new genomes and annotations since launch, as well as full integration with AlphaFold.

2023

science-technologyupdates-from-data-resources

17 April 2023 Photo of EMBL alumni in current lab in Spain

After EMBL: Thomas Graf

People & Perspectives Alumnus Thomas Graf reflects on his time at EMBL, offering an update on his whereabouts and advice for young scientists.

2023

alumnipeople-perspectives

12 April 2023 Photo of Eduard Avetisyan smiling and standing next to the servers at EMBL Hamburg.

We are EMBL: Eduard Avetisyan on the role of IT in structural biology

Lab MattersPeople & Perspectives Eduard Avetisyan leads the EMBL Hamburg IT team. He joined EMBL after transitioning from particle physics research to IT. Besides providing standard IT user support, his team also enables smooth processing and computational analysis of structural biology data. Here, he talks about the joys and…

2023

lab-matterspeople-perspectives

11 April 2023 Phylogenetic tree with beams of light to represent data

MAPLE: a phylogenetic tool for pandemic-scale genome data

Science & Technology EMBL-EBI researchers have developed a new tool capable of performing state-of-the-art phylogenetic inference on larger datasets than previously thought possible.

2023

research-highlightssciencescience-technology

11 April 2023

EMBL and Montenegro: boosting cooperation and enhancing awareness

ConnectionsLab Matters Europe’s life sciences laboratory EMBL on 5 April welcomed Council delegates Ivana Lagator and Lidija Vukcevic from the Montenegrin Ministry of Science and Technological Development, and University of Montenegro representative Professor Danilo Mrdak, to discuss expanding research and training…

2023

connectionsembl-member-stateslab-matters

4 April 2023 A mobile lab on a road, with the TREC logo on the side.

TREC is underway!

EMBL Announcements EMBL’s planetary biology flagship TREC expedition has officially started. The new project applies EMBL's expertise and technologies in molecular and cellular biology to current environmental challenges, and connects with a wide range of research disciplines.

2023

embl-announcementseventsscience

4 April 2023 Title slide for the conference, The organism and its environment

Life in context

Science & Technology Upcoming EMBO/EMBL symposium provides a forum to explore how organisms function together, and how they react or adapt to changes at different molecular levels.

2023

eventsscience-technology

3 April 2023 Two male scientists with safety glasses at EMBL Imaging Centre

Dispensing microscopy expertise

Lab MattersScience & Technology Home to some of Europe’s most cutting-edge tools in molecular biology, EMBL has long shared its expertise and access to these tools through an extensive repertoire of courses, conferences, seminars, and other training. And now included in this mix is a job shadowing programme at EMBL Imaging…

2023

lab-mattersscience-technology

30 March 2023 Science illustration representing two embryos imaged using the Brillouin microscopy technique. The embryo in the front is a mouse embryo at 20h and the one in the back a Phallusia mammillata embryo. A laser beam crosses the samples to analyse tissue stiffness (here represented by acoustic waves).

Shining light on the mechanics of embryo development

Lab MattersScience & Technology A new microscope built by EMBL researchers, based on Brillouin scattering principles, allows scientists to observe the dynamics of mechanical properties inside developing embryos in real time.

2023

lab-matterssciencescience-technology

30 March 2023 Profile picture of Cornelius Gross, interim head of EMBL Rome

ERC Advanced Grant awarded to EMBL Rome researcher

EMBL AnnouncementsLab Matters Interim head of EMBL Rome Cornelius Gross has been awarded an Advanced grant from the European Research Council (ERC) for his project TERRITORY, aimed at investigating the neural basis of territorial aggression and fear.

2023

embl-announcementslab-matters

23 March 2023 Portrait of a person looking at the camera. In the background there are trees and a white building

Welcome: Alejandro Torres-Sánchez

Lab MattersPeople & Perspectives The new group leader is setting up the first purely theory-focused research group at EMBL Barcelona. He aims to understand fundamental biological principles using mathematical models and computer simulations, in close collaboration with experimental researchers across EMBL.

2023

lab-matterspeople-perspectives

21 March 2023 Male scientist in blue shirt standing in front of a building with glass doors.

Welcome: Thomas Quail

Lab MattersPeople & Perspectives New group leader Thomas Quail studies the fundamental processes that determine how proteins organise the genome inside a cell.

2023

lab-matterspeople-perspectives

20 March 2023 Team leader Gergely Papp.

Welcome: Gergely Papp

Lab MattersPeople & Perspectives Together with his team, Gergely Papp pushes the frontiers of technology development in the field of structural biology.

2023

lab-matterspeople-perspectives

17 March 2023 Liz Duke standing on the left side of the photo, with EMBL Hamburg's P14 beamline and a big screen on the right.

Molecules to Ecosystems: Liz Duke on X-ray imaging

Lab MattersPeople & Perspectives Biological X-ray imaging is an emerging technology that uses X-rays to image tissues or even entire organisms. It will play an important role in EMBL Hamburg’s future service portfolio, and will allow studying life on multiple scales. Team Leader Liz Duke discusses her plans to establish X-ray…

2023

lab-matterspeople-perspectives

15 March 2023 Image of a group of people behind a large, black table with two cakes on it to celebrate EMBL Barcelona’s fifth anniversary

EMBL Barcelona: Five years down the road

Lab Matters EMBL’s site by the sea completed its fifth year of operations. We look back at some key milestones and achievements since 2017.

2023

lab-matters

7 March 2023 Black and white photograph showing a group of scientists standing in frnot of a building.

Tracing the history of women in science at EMBL

Lab Matters On the occasion of International Women’s Day 2023, EMBL archivist Maria Papanikolaou discusses the traces left by the women in science who have passed through EMBL, irrevocably changing the organisation in small and big ways.

2023

lab-matters

1 March 2023 Moisés Bueno is standing next to the transfer robot. The robot has a form of a yellow robotic arm on a stand. Behind is the CrystalDirect™ Harvester, which is a white cuboid with two transparent dimmed windows for laser protection.

Biology meets engineering

Lab MattersScience & Technology Physicists, engineers and robotics experts work together in EMBL Hamburg’s Instrumentation Team to design instruments that support structural biology research. The team has finished a transfer robot that facilitates automated handling of protein crystals with care and precision. This will help…

2023

lab-mattersscience-technology

23 February 2023 Image showing the pulsed green laser exciting the photoacoustic signal of the sample in the cuvette.

Spotlight: Using light and sound to see into the brain

Lab MattersScience & Technology Researchers in the Prevedel Group use photoacoustic spectroscopy setup to test and optimise probes before their usage in mouse neuroscience.

2023

lab-matterspicture-of-the-weekscience-technology

20 February 2023 The Estonian flag

EMBL welcomes Estonia as full member

EMBL AnnouncementsLab Matters The Baltic nation of Estonia has become a full member of EMBL, joining the organisation as its 28th member state.

2023

embl-announcementslab-matters

16 February 2023

New EU-funded Project: Fragment-Screen

Lab MattersScience & Technology EMBL is one of the partners of this project that aims to accelerate drug discovery and development, bringing in expertise from EMBL Grenoble and EMBL-EBI.

2023

lab-mattersscience-technology

15 February 2023 A photo of a scientist operating one of the instruments at the EMBL SPC Facility.

Supporting scientists across Europe: the SPC Facility at EMBL Hamburg

Lab MattersScience & Technology EMBL Hamburg’s Sample Preparation and Characterisation (SPC) Facility offers scientists access to almost all available biophysics technologies. The facility’s staff provides advice and support with experiments and data analysis. The facility is conveniently located just next to the EMBL…

2023

lab-mattersscience-technology

13 February 2023 Female scientist stands in front of lab bench

Welcome: Hanh Vu

Lab MattersPeople & Perspectives Group Leader Hanh Vu studies ‘immortal’ flatworms that can grow and de-grow to understand better factors that determine organisms’ sizes.

2023

lab-matterspeople-perspectives

11 February 2023 Female student stands in front of a lab bench

Scientific passion that seeds passion

Lab Matters A recent student visitor shares her impressions from visiting EMBL’s Vincent group as we recognise International Day of Women and Girls in Science.

2023

lab-matters

7 February 2023 BII and EMBL logos are on a white band set against a wavy green background

Promoting European innovation in the life sciences

ConnectionsLab Matters One of EMBL’s core missions is the development and transfer of scientific know-how and technologies to academia, industry, and commercial entities to facilitate further research, innovations, and commercialisation for the benefit of society at large. Working across Europe, EMBL has partnerships…

2023

connectionslab-matters

31 January 2023

ERC Consolidator Grant success at EMBL

EMBL AnnouncementsLab Matters EMBL Rome group leader Jamie Hackett receives EUR 2 million for the ModLogic project, aimed at understanding how chromatin modifications impact gene activity.

2023

embl-announcementslab-matters

25 January 2023 A group photo from the BiOcean5D launch meeting

BIOcean5D targets marine biodiversity

ConnectionsLab Matters EMBL hosts inaugural meeting for major interdisciplinary project designed to boost understanding of ocean life

2023

connectionslab-matters

20 January 2023 bright yellow and striped flatworms

Spotlight: A ‘devil’ of a flatworm

Lab MattersScience & Technology Tasmanian flatworms add to an EMBL researcher’s collection as she studies principles that control animal body size.

2023

lab-matterspicture-of-the-weekscience-technology

19 January 2023 Cross sections of mouse colon, with mucus stained in blue and nuclei stained in red. The right section has been treated with a mucolytic agent.

Spotlight: Colours of the colon

Lab MattersScience & Technology Mucus present in the mouse colon can be visualised using Alcian blue staining, as imaged here by EMBL predoctoral fellow Linda Decker.

2023

lab-matterspicture-of-the-weekscience-technology

9 January 2023

New molecular insights on medical cannabis

Science & Technology EMBL Grenoble researchers have investigated the interaction between THC and some proteins it might bind to. In a recent study, they showed in vitro that THC inhibits an important human enzyme called autotaxin.

2023

sciencescience-technology

4 January 2023 Confocal microscopy of dynamic concentration of nucleoporins (top) and 3D model of postmitotic assembly pathway of the nuclear pore complex over a time scope of 60 minutes during cell division.

Step-by-step guide to nuclear pore complex assembly

Science & Technology EMBL Heidelberg researchers and their collaborators reveal how the nuclear pore complex, one of the biggest molecular machines in eukaryotic cells, is assembled one protein at a time.

2023

sciencescience-technology

23 December 2022 Several zebrafish embryos in different colours during gastrulation

Spotlight: Zebrafish embryos to make this season jolly

Lab MattersScience & Technology Zebrafish embryos during gastrulation, a very early stage of development, to study the effect of temperature on vertebrate embryo development.

2022

lab-matterspicture-of-the-weekscience-technology

12 December 2022 A mother and her child looking through a microscope

Celebrating science in Grenoble

ConnectionsLab Matters In October 2022, EMBL Grenoble participated in the annual science outreach event Parvis des Sciences, organised by the GIANT campus under the umbrella of the French science week – La Fête de la science.

2022

connectionslab-matters

8 December 2022 Image of Prof. Peter B. Becker in the laboratory

New chair of EMBL Council

EMBL AnnouncementsLab Matters EMBL alumnus and eminent molecular biologist Peter B. Becker has been named the next chair of EMBL’s Council as of January 2023.

2022

embl-announcementslab-matters

7 December 2022 Two scientists in a lab conversing

Making a great postdoc program even better with our member states

EMBL AnnouncementsLab Matters EMBL’s EIPOD-Learning in Context programme focuses on interdisciplinary research that explores ‘life in context’ and adds a new collaborative dimension with member state organisations.

2022

embl-announcementslab-matters

1 December 2022

Getting closer to stopping toxoplasmosis infection

Science & Technology Recent studies supported by EMBL Grenoble’s expertise in structural biology research and scientific services have identified Altiratinib as a potential drug to stop toxoplasmosis infection and opened up treatment options against malaria.

2022

sciencescience-technology

30 November 2022 Portrait of Talya Dayton propped up on a balcony rail

Welcome to EMBL: Talya Dayton

Lab MattersPeople & Perspectives The new group leader in Barcelona aims to understand how cells behave in health and in disease, and approaches her favourite hobby, cooking, very similarly to her work in the lab.

2022

lab-matterspeople-perspectives

22 November 2022 Image portraying the three scientists who received the ERC Starting grant

EMBL scientists receive prestigious ERC Starting Grant

EMBL AnnouncementsLab Matters Three EMBL scientists received this year’s ERC Starting Grants, and will be awarded €1.5 million over five years to carry out research projects.

2022

embl-announcementslab-matters

21 November 2022 male scientist in green shirt and dark pants stands outside in front of tree

Welcome Jordi van Gestel

Lab MattersPeople & Perspectives Looking to understand microbial predator-prey relationships, EMBL’s newest group leader tackles a molecular ‘arms race’ in his lab.

2022

lab-matterspeople-perspectives

18 November 2022 A molecular illustration in the background showing ribosomes inside a Mycoplasma cell. A banner on top reads 'EMBLetc. Issue 99'

EMBLetc. receives digital-first makeover

EMBL AnnouncementsLab Matters The biannual magazine that highlights EMBL’s research, people, and projects now has a new online home.

2022

embl-announcementslab-matters

3 November 2022 View from above of a small room with several tools, cables and pieces of technology. A rectangular box, a robotic arm and a device are highlighted in green.

Two in one: combining MASSIF-1 and CrystalDirect

Lab MattersScience & Technology Researchers and engineers have integrated a CrystalDirect harvester into the fully automated beamline MASSIF-1, a unique combination of structural biology technologies that is now open to external academic users.

2022

lab-mattersscience-technology

27 October 2022 Male scientist looking towards the camera, against a blurred background

Setting priorities for preprints and open science

Lab MattersPeople & Perspectives Newly appointed member of the ASAPbio Board of Directors, EMBL Group Leader Gautam Dey speaks about preprints, data management, and open science.

2022

lab-matterspeople-perspectives

21 October 2022 A female scientist in a blue dress stands in front of blurred woodsy background

Welcome: Flora Vincent

Lab MattersPeople & Perspectives After a postdoc at Weizmann Institute of Science in Israel, Flora Vincent has joined EMBL’s Developmental Biology unit to further explore the world of phytoplankton.

2022

lab-matterspeople-perspectives

20 October 2022 Two EMBL staff members looking at a piece of equipment

Teaming up to drive forward time-resolved crystallography

Lab MattersScience & Technology The recent construction of the new ID29 beamline in Grenoble is pioneering a new way of doing experiments in time-resolved crystallography and opening up technology transfer possibilities

2022

lab-mattersscience-technology

11 October 2022 EMBL scientists sampling at the coastline of Iceland in August 2022

Examining life along Iceland’s coasts

Lab MattersScience & Technology The final pilot project in Iceland marked the countdown to the ‘Traversing European Coastlines’ (TREC) expedition to study coastal ecosystems and their response to changes in the environment.

2022

lab-mattersscience-technology

29 September 2022 young girl in lab coat

Tools for teachers

Lab Matters EMBL reminds teachers of freely available educational resources and workshops just in time for school.

2022

lab-matters

21 September 2022 Photo of the speakers during the panel discussion. Edith Heard is talking. In front of the panel, there is the audience seen from the back, and behind the panel there are banners with the DESY PETAR IV logos and a slide displaying the names of the panellists.

PETRA IV and future opportunities at EMBL Hamburg beamlines

Lab MattersScience & Technology EMBL joined a kick-off event focusing on the developments related to the upgrade of the PETRA III synchrotron storage ring to PETRA IV at the DESY campus, where EMBL Hamburg is located. PETRA IV could open new possibilities at EMBL Hamburg, contributing to the goals of the EMBL Programme…

2022

lab-mattersscience-technology

20 September 2022 8 representatives of both the Dieter Schwarz Foundation and EMBL are standing in the EMBL Imaging Centre foyer facing the camera

Life Science Alliance starts new chapter

ConnectionsLab Matters Dieter Schwarz Foundation renews 3-year funding to EMBL for the EMBL | Stanford Life Science Alliance, a unique international collaboration bringing together researchers from the two leading institutions to develop transformative technologies and accelerate biomedical research.

2022

connectionslab-matters

15 September 2022 The foreground shows two yellow pipes representing the human gastrointestinal tract coming together, representing the confluence of donor and recipient gut ecosystems. Bacteria can be seen as green shapes inside the pipes and various kinds of interactions between them are shown symbolically as a mixing of colours.

When microbiomes collide

Science & Technology EMBL researchers used data from over 300 human faecal microbiota transplants to gain an ecological understanding of what happens when two gut microbiomes clash.

2022

sciencescience-technology

9 September 2022 A female career advisor at computer participates in webinar

Insights into scientific careers

Lab Matters As the career landscape continues to change for PhDs and postdocs, the EMBL Fellows’ Career Service offers webinars that present professional options in and beyond academia.

2022

eventslab-matters

7 September 2022 Female scientist stands in laboratory setting

Augmenting science

Lab Matters The Scientific Visitor Programme shares EMBL tools and talent with outside researchers in collaborative, multidisciplinary environments.

2022

lab-matters

1 September 2022 4D reconstruction of a mouse limb with lateral and top view.

Building the ideal limb

Science & Technology EMBL researchers use a “fearless” computer reconstruction and a two-centuries-old mathematical approach to study limb bud growth.

2022

sciencescience-technology

31 August 2022 A Physarum polycephalum with different colours, where each colour shows the expansion of the cell at various time points.

Spotlight: A giant in action

Science & Technology Physarum polycephalum, a single, giant cell containing tens of thousands of nuclei is large enough to be photographed with a phone.

2022

picture-of-the-weekscience-technology

24 August 2022 A building with glass facades and courtyard in front.

Spotlight: EMBL Imaging Centre, Heidelberg

Lab Matters EMBL’s imaging centre makes advanced microscopy technologies accessible to the international scientific community.

2022

lab-matterspicture-of-the-week

5 August 2022 A rod-like structure with green and magenta segments representing cellular markers.

Making patterns visible

Science & Technology How do gene expression patterns result in the generation of different cell types? Scientists at EMBL Heidelberg used the zebrafish notochord to find out.

2022

sciencescience-technology

4 August 2022 An illustration provides representation of fingers hovering over a cell phone

Zooming in to get the full picture

Science & Technology EMBL and UW researchers plus additional collaborators have constructed a complete map of fruit fly embryonic development using machine learning. This research is foundational to better understanding overall embryo development in other species, including humans.

2022

sciencescience-technology

1 August 2022

Shining a light on how bacteria interact

Science & Technology Machine learning has helped researchers uncover new insights into how bacteria infect host cells.

2022

research-highlightssciencescience-technology

26 July 2022 Group of around 100 people posing in a terrace in front of the sea.

A summer of scientific exchange in Barcelona

ConnectionsLab Matters EMBL’s site by the sea hosted a trio of conferences this summer, covering topics ranging from vascular biology to engineered living systems to evolution.

2022

connectionslab-matters

20 July 2022 A woman stands in front of shelving filled with notebook binders.

Welcome: Maria Papanikolaou

Lab MattersPeople & Perspectives EMBL’s new archive and records manager, Maria Papanikolaou, explains the dual role she and an additional colleague will have in the Office of Science Information Management.

2022

lab-matterspeople-perspectives

18 July 2022 Large, elongated purple molecule has an on/off switch on it pointed to on.

The retron switch

Science & Technology EMBL researchers now understand the function of an elusive small DNA in bacteria and have developed a tool that can be used to better understand what might ‘switch on’ bacterial immune defences.

2022

sciencescience-technology

14 July 2022 Visualising the ocean below and above surface, showing several species and giving written details on the ocean microbiome composition

Priorities for ocean microbiome research

Science & Technology Microbial communities play essential roles in ocean ecology and planetary health. A recent publication highlights priorities for understanding and protecting ocean microbiomes.

2022

sciencescience-technology

13 July 2022 Decorative image showing a double helix DNA road and with what look like road signs.

Uncharted territories in the human genome

Science & Technology Scientists identify previously unexplored gene segments to be added to human genome databases.

2022

research-highlightssciencescience-technology

5 July 2022 A view of the EMBL Imaging Centre with fields in the background

The EMBL Imaging Centre: making it happen

Connections Creating a cutting-edge facility for the global life science community doesn't happen overnight. We spoke to some of those who worked to turn this dream into a reality.

2022

connectionsevents

29 June 2022 Two scientists are surrounded by an illustration of various types of molecules in pastel colours

EMBL 2021 Annual Report published

EMBL AnnouncementsLab Matters EMBL’s 2021 Annual Report is now available, sharing mission highlights from the year in a new digital-first, sustainable format.

2022

embl-announcementslab-matters

22 June 2022 Edith Heard

The world needs science, and science needs women

Lab MattersPeople & Perspectives EMBL Director General Edith Heard joined other L’Oreal-UNESCO Laureates in Paris for a series of events celebrating these outstanding researchers and their contributions.

2022

lab-matterspeople-perspectives

10 June 2022 A colourful structural model of the doughnut-shaped human nuclear pore complex seen from above.

Puzzling out the structure of a molecular giant

Science & Technology Scientists have solved several mysteries around the structure and function of a true molecular giant: the human nuclear pore complex. They created the most complete model of the complex thanks to combining the program AlphaFold2 with cryo-electron tomography, integrative modelling, molecular…

2022

sciencescience-technology

8 June 2022 Two female scientists shown against a green background

2022 EMBL Alumni Awards Winners announced

EMBL Announcements Two former EMBL staff members have been recognised for their outstanding contributions to research in the fields of brain evolution and cancer.

2022

alumniembl-announcements

7 June 2022 Female scientist photographed in a garden

Welcome: Pascale Cossart

Lab MattersPeople & Perspectives Pascale Cossart, one of the world’s foremost authorities on the biology of Listeria, brings four decades of expertise in intracellular bacterial parasitism to EMBL as a visiting scientist.

2022

lab-matterspeople-perspectives

3 June 2022 he internal structure of a mitotic chromosome is shown with colourful threads representing DNA, one of which is shown being packaged into loops by the condensin protein complex. The background shows mitotic chromosomes in the cellular space

Shaping up the genome for cell division

Science & Technology Researchers have discovered the mechanism by which a family of DNA motor proteins packages loosely arranged strands of DNA into compact individual chromosomes during cell division.

2022

sciencescience-technology

2 June 2022 BII and EMBL logos are on a white band set against a wavy green background

Teamed up to innovate

ConnectionsLab Matters A new formal collaboration agreement enables will help smooth the transition from fundamental science to innovation.

2022

connectionslab-matters

1 June 2022

EMBL in Italy event held at GSK Vaccines in Siena

Connections The GSK Vaccines site in Siena hosted the annual EMBL in Italy event. The hybrid meeting brought together industry leaders, representatives from biotech start-ups, data scientists, and researchers from academia.

2022

alumniconnections

21 May 2022 Portrait photo of Edith Heard

Edith Heard elected as a member of The Royal Danish Academy of Sciences and Letters

EMBL AnnouncementsLab Matters EMBL Director General Edith Heard has been elected as a foreign member of The Royal Danish Academy of Sciences and Letters in recognition of her academic excellence. Heard is among 15 new members of the Academy, which has been advancing basic research and interdisciplinarity for nearly 280 years.

2022

embl-announcementslab-matters

18 May 2022 The visiting group from the Business Academy Aarhus during lunch at the EMBL Hamburg’s terrace

EMBL Hamburg is helping train lab techs of the future

Lab Matters Students from the Business Academy Aarhus visit EMBL Hamburg annually. Many of them return later as trainees to gain experience as lab technicians. EMBL Hamburg offers great opportunities to learn diverse techniques and work with various equipment. This experience helps them in their future jobs in…

2022

lab-matters

11 May 2022 Man standing on a balcony

Peter Harrison – Genome Analysis Team Leader

Lab MattersPeople & Perspectives Peter Harrison discusses the importance of data accessibility and his passion for biodiversity and agricultural genomics.

2022

lab-matterspeople-perspectives

10 May 2022

Royal Society honour for Eileen Furlong

EMBL AnnouncementsLab Matters EMBL’s Head of Genome Biology announced as Fellow of the Royal Society for her exceptional contributions to science.

2022

embl-announcementslab-matters

6 May 2022 Drawing of two chromosomes in which a highlighted area is switched around.

Flip-flop genome

Science & Technology Researchers at EMBL Heidelberg found that inversions in the human genome are more common than previously thought, which impacts our understanding of certain genetic diseases.

2022

sciencescience-technology

5 May 2022 Colourful vertical panels each show different microscopic images possible with the high-tech tools in EMBL's Imaging Centre

Enabling imaging across scales

EMBL Announcements EMBL’s first Imaging Centre Symposium will occur onsite at EMBL and include tours of the new Imaging Centre on 31 May, introducing participants to the facility and its staff and featuring talks on the rapid developments in imaging technologies that have led to notable biological and medical…

2022

embl-announcementsevents

5 May 2022 Microscopy image showing mouse cells in blue on a dark background. The mouse cells look like little blue blobs.

Interpreting bioimages with deep learning

Science & Technology Virginie Uhlmann shares her tips for using deep learning for bioimage analysis in the life sciences.

2022

perspectivessciencescience-technology

28 April 2022 Microsocopy image of Pair of somites. Blue is a nuclear marker (DAPI) and red is an apical marker (ZO-1).

Unravelling the origins of the human spine

Science & Technology Scientists at EMBL Barcelona have created for the first time a 3D in vitro model that recapitulates the periodic formation of human somites – structures that give rise to the spinal column.

2022

sciencescience-technology

27 April 2022 Portrait of Kristina Djinović-Carugo

Next Head of EMBL Grenoble appointed

EMBL AnnouncementsLab Matters Professor Kristina Djinović-Carugo has been appointed as the next head of EMBL Grenoble. She will join EMBL in July from the Max Perutz Laboratories at the University of Vienna, where she is currently Head of the Department of Structural and Computational Biology and full Professor of Structural…

2022

embl-announcementslab-matters

27 April 2022 Kristina Djinović-Carugo sitting at her desk.

Meet the next Head of EMBL Grenoble

Lab MattersPeople & Perspectives Slovenian structural biologist Kristina Djinović-Carugo will join EMBL in July as the new Head of EMBL Grenoble. We spoke to her about her background, research interests, and plans for EMBL Grenoble.

2022

lab-matterspeople-perspectives

12 April 2022

EMBL consolidates ties with Sapienza University

ConnectionsLab Matters EMBL and the Sapienza University of Rome confirm their reciprocal interest in intensifying collaborations and launch new opportunities for exchange of expertise

2022

connectionslab-matters

8 April 2022 a metaphor for the process of epigenetic inheritance

A metaphor for epigenetic inheritance

Science & Technology Recent studies from the Hackett group at EMBL Rome have revealed new insights on the mechanism regulating transmission of non-genetic information during embryonic development, and inspired a scientific illustration

2022

sciencescience-technology

6 April 2022 Portrait photo of Matthias Hentze surrounded by a colourful background

Matthias Hentze receives Centenary Award

EMBL AnnouncementsLab Matters EMBL Heidelberg’s Matthias Hentze receives the Biochemical Society’s Centenary Award for his discoveries in RNA biology.

2022

embl-announcementslab-matters

30 March 2022 Man standing in front of a wall with scientific imagery including protein structures

Welcome: John Lees

Lab MattersPeople & Perspectives John Lees joins EMBL-EBI as a Group Leader in Pathogen informatics and modelling.

2022

lab-matterspeople-perspectives

23 March 2022 Two Drosophila embryos stained with fluorescent dye on a purple background that indicates either solid or liquid state

From liquid to solid to drive development

Science & Technology Condensates are membraneless organelles that control specific functions within a cell. Scientists at EMBL Heidelberg have shown how the physical state of condensates can influence biological function.

2022

sciencescience-technology

20 March 2022 Portrait photo of EMBL Group Leader Judith Zaugg against a green background.

Judith Zaugg from EMBL Heidelberg receives ERC Consolidator Grant

EMBL AnnouncementsLab Matters Judith Zaugg, Group Leader at EMBL Heidelberg, has been awarded an ERC Consolidator Grant of €2 million funded under the European Union’s Horizon Europe research and innovation programme. Over the next five years, the grant will enable her group to study cellular interactions in the human bone…

2022

embl-announcementslab-matters

17 March 2022 EMBL statement visual

EMBL’s statement on the invasion of Ukraine

EMBL AnnouncementsLab Matters EMBL condemns in the strongest terms the unjustified military invasion of Ukraine by the Russian Federation, with the support of Belarus, and the resulting loss of life and human suffering. We express our deepest sympathy to the Ukrainian people and to all the victims of this war.  As an…

2022

embl-announcementslab-matters

16 March 2022 Image of a whole lung piece and its internal delicate structure

Putting Cryptococcus in context

Science & Technology EMBL’s imaging technology helps researchers gain insights in the fungus’ journey from the lung to the brain.

2022

sciencescience-technology

4 March 2022 Colourful shapes are set against a black background and white grid, symbolic of aspects of infection biology.

A postdoc conference spotlighted in tweets

Lab Matters EMBL hosted a futuristic infection biology conference, but it offered even more: an opportunity for postdocs to share their work and network towards future research homes.

2022

eventslab-matters

4 March 2022 Science art expressing the concept of transcriptional neighbourhoods regulating transcript isoform lengths and expression levels.

Understanding genomes, piece by piece

Science & Technology Genomes are made up of thousands of individual pieces – genes – which are expressed at different levels. Researchers at EMBL have shed light on how the placement of a gene affects its expression, as well as that of its neighbours.

2022

sciencescience-technology

4 March 2022 A gloved hand holds a slide with visible wells containing Matrigel immersed in culture medium. A magnified close-up shows a mouse embryo developing over the course of 48 hours

A 3D culture model to study embryo growth

Science & Technology A recent study by EMBL researchers proposes a new method to grow early embryos in the laboratory. With a 3D culture set-up, scientists can closely monitor the changes embryos undergo around the time of implantation.

2022

sciencescience-technology

2 March 2022 woman stands in front of computer in workplace

Academia, industry, or somewhere else?

Lab Matters New study: EMBL PhDs and postdocs develop skills that make them highly employable in roles that drive research and innovation in academia, industry, and other sectors.

2022

alumnilab-matters

2 March 2022 Image composition showing a building with sun reflecting off the glass and microscopy images of microorganisms in multiple colours.

‘The World of Molecular Biology’ exhibition

EMBL AnnouncementsLab Matters The new permanent ‘The World of Molecular Biology’ exhibition will open in mid-2023 at EMBL’s headquarters in Heidelberg. It will encourage people to actively engage with science and its relevance for everyday life.

2022

embl-announcementslab-matters

25 February 2022 Three colourful overlapping circles arranged in a row, a fruit-fly embryo being visible within each. Small circles within the embryos represent cell lineages.

Converging lenses on embryo development

Science & Technology Researchers from the Furlong group at EMBL have come up with a way to observe the development of fruit-fly embryos simultaneously at the genetic and cellular levels, generating a high-resolution and integrated view of how different cell lineages form.

2022

sciencescience-technology

23 February 2022 A photo of the campus of the Aarhus University buildings and green lawn.

Molecular medicine across borders

ConnectionsLab Matters The 11th annual Nordic EMBL Partnership for Molecular Medicine meeting was hosted in virtual format by DANDRITE, the Danish node of the Partnership, from 31 January–2 February 2022. The programme included updates from all partnership nodes, discussions about opportunities for new collaborations,…

2022

connectionslab-matters

23 February 2022 A male scientist in a white shirt stands at a walkway railing.

Welcome: Michael Dorrity

Lab MattersPeople & Perspectives Michael Dorrity, one of EMBL’s newest group leaders, is studying how the environment influences early life stages in zebrafish.

2022

lab-matterspeople-perspectives

10 February 2022 Pfizer logo with pipette tips in the background

Pfizer joins the Open Targets consortium

Connections Open Targets, a consortium focused on drug target identification, prioritisation, and validation, announced today that Pfizer has joined as a partner.

2022

announcementsconnectionsscience

9 February 2022 The logos of EMBL and the Latvian Biomedical Research and Study Centre

EMBL and Latvia deepen collaboration

Connections Agreement signed with Latvia’s Biomedical Research and Study Centre will boost academic exchange and collaboration on some of the largest challenges facing human and planetary health.

2022

connectionsevents

1 February 2022 A photograph of the Amazonian lancehead snake Bothrops atrox

Decoding the secrets of snake venom

Science & Technology EMBL Hamburg’s Grzegorz Chojnowski from the Wilmanns Group developed software called findMySequence, which identifies proteins’ amino-acid sequences based on electron cryo-microscopy and X-ray crystallography data. It’s useful for identifying unknown proteins in samples from natural sources.

2022

sciencescience-technology

27 January 2022 A headshot of Mark Daly with dark background behind him.

Fostering excellence, diversity, and mobility in the Nordic EMBL Partnership

ConnectionsLab Matters Ahead of the annual meeting of the Nordic EMBL Partnership for Molecular Medicine, we spoke with its new Speaker, Mark Daly. Mark Daly, FIMM Director, recently accepted the post of Speaker of the Nordic EMBL Partnership. He explains his vision of the future cooperation between EMBL and the Nordics.

2022

connectionseventslab-matters

24 January 2022 Three women are seen in front of a computer, with the electron micrograph of a woodlouse visible on the screens

EMBL Imaging Centre kickstarts training with workshop for undergraduates

Lab Matters The new EMBL Imaging Centre held its first on-site training workshop, introducing undergraduate students to the basics of volume electron microscopy. This marks the first of many opportunities to aid capacity-building in imaging techniques in Europe.

2022

lab-matters

21 January 2022 The cross-section of a cell expressing a green fluorescently tagged protein and illuminated by a blue laser is visible in the foreground, surrounded by a vortex of cells

Cell sorting enters a new dimension

Science & Technology EMBL researchers, in collaboration with BD Biosciences, have demonstrated a new technology that allows rapid image-based sorting of cells. The new technology represents a major upgrade to flow cytometry and has applications in diverse life science fields.

2022

sciencescience-technology

19 January 2022 "From Molecules to Ecosystems" are words on top of a collage of images that span from molecules to ecosystems

A new era for European molecular biology

EMBL AnnouncementsLab Matters EMBL announces details about its next programme, ‘Molecules to Ecosystems’. It will guide studying life across scales and in context with changing environments.

2022

announcementsembl-announcementslab-matters

18 January 2022 Science illustration composed by a photographic film highlighting three-dimensional structures of a protein complex involved in splicing.

Capturing ‘snapshots’ of a crucial step in RNA splicing

Science & Technology The Galej group at EMBL Grenoble has recently obtained high resolution snapshots of a crucial step in RNA splicing involving the U2 snRNP complex, a crucial component of the human spliceosome.

2022

sciencescience-technology

14 January 2022 Woman standing next to a hedge

Welcome: Melissa Harrison

Lab MattersPeople & Perspectives Melissa Harrison joins EMBL-EBI as the new Team Leader of Literature Services. We found out more about her plans for open access publishing and Europe PMC.

2022

lab-matterspeople-perspectives

3 January 2022 Mixture of life science symbols inside a circle set against background of green and blue

The start of a journey

Lab MattersPeople & Perspectives This year marks the beginning of EMBL’s next programme ‘Molecules to Ecosystems’ to advance the understanding of life across scales and in the context of changing environments.

2022

lab-matterspeople-perspectives

22 December 2021 Scientific illustrations of MEG3, a very large RNA involved in cell proliferation. IAB and EMBL logos are located in the center of the illustration.

EMBL-IAB collaboration on the rise

ConnectionsLab Matters The memorandum of understanding (MoU) signed between EMBL and the Institute for Advanced Biosciences (IAB) a year ago has already catalysed new grants for joint research projects related to cancer and infection biology, thereby deepening collaborative activities.

2021

connectionslab-matters

21 December 2021 A model of the doughnut-shaped nuclear pore complex. Individual molecules are marked in various colours.

Observing the secret life of molecules inside the cell

Science & Technology EMBL Hamburg’s Kosinski Group, the Beck Laboratory at the Max Planck Institute of Biophysics, and colleagues at EMBL Heidelberg recorded the nuclear pore complex contracting in living cells. They visualised the movement with an unprecedented level of detail with help of new software called…

2021

sciencescience-technology

20 December 2021 Concentric circles and lines in different colours, representing fingerprints. Text: "Equality, Diversity, and Inclusion Strategy."

Fostering diversity and equality

Lab Matters Showing a continued commitment to providing a diverse and inclusive organisation for conducting leading molecular biology research, EMBL has launched an Equality, Diversity, and Inclusion (EDI) strategy.

2021

lab-matters

20 December 2021 A detailed structure map shows two proteins interacting in the foreground, each shown in a different colour. The background shows small green dots marking bacteria

Solving molecular puzzles to find the perfect fit

Science & Technology Using cryo-EM and structural biology techniques, EMBL researchers have shown how two proteins of Legionella pneumophila interact. This finding sheds light on a mechanism critical to the infection process and could lead to the development of new drugs to treat pneumonia.

2021

sciencescience-technology

15 December 2021 An outline of Earth, covered with depictions of bacteria. The image of Earth is within a the frame of a computer window. There is an “Upload file” button on the bottom left, and a mouse cursor on the right.

Connecting the dots between bacterial genes around the world

Science & Technology Bork Group at EMBL Heidelberg analysed a new global gene database to study how genes emerge and spread across various habitats on our planet. In the future, the group will expand the database and use it for studying microbial gene evolution and dispersal at a finer-grained scale.

2021

sciencescience-technology

9 December 2021 Colourful interwoven coils are displayed against a grid of small black and white photographic images.

A gallery of human RNA polymerases

Science & Technology New structural biology research provides fundamental information critical to understanding enzyme mutations connected to rare diseases and cancers.

2021

sciencescience-technology

9 December 2021 Portrait photo of Eileen Furlong against blue-green background.

Eileen Furlong honoured with Leibniz Prize

EMBL AnnouncementsLab Matters EMBL Senior Scientist and Head of the Genome Biology Unit is among the researchers honoured for outstanding work by the German Research Foundation (Deutsche Forschungsgemeinschaft, DFG).

2021

embl-announcementslab-matters

9 December 2021 Logos of CNRS and EMBL with text “memorandum of understanding”

Strengthening collaborations in France

ConnectionsLab Matters EMBL and the French National Centre for Scientific Research (CNRS) signed a memorandum of understanding.

2021

connectionslab-matters

8 December 2021 An illustration of the human gut, with coloured shapes representing bacteria. Three different drugs and drug combinations are shown affecting the bacteria, represented by changes in colour

The impact of drugs on gut microbes is greater than we thought

Science & Technology Researchers studying a massive cohort of European patients have found that commonly prescribed drugs for cardiometabolic disorders can have long-term effects on the gut microbiome. Such effects can complicate the understanding of how disease affects the microbiome and must be taken into…

2021

sciencescience-technology

7 December 2021 A cartoon image showing a person's arm and a needle with a vaccine being injected into it. The text on the left reads: "EMBL research: How structural biologists at EMBL Hamburg help to develop and improve RNA vaccines"

How structural biology helps to make RNA vaccines

Science & Technology RNA vaccines, such as the ones for COVID-19, represent a new approach in vaccine technology. Cy Jeffries, faculty staff scientist at EMBL Hamburg, explains the clever technology behind RNA vaccines, and how structural biology contributes to its development. EMBL Hamburg collaborated on several…

2021

sciencescience-technology

29 November 2021 Male scientist in front of blurred woodland background

Welcome: Niccolò Banterle

Lab MattersPeople & Perspectives Using gene editing and three types of microscopy, one of EMBL’s newest group leaders is deciphering the functions of one of the smallest molecules involved in cell division, motility, and signalling, known as a centriole.

2021

lab-matterspeople-perspectives

25 November 2021 Female scientist in front of a background of green plants

Welcome: Maria Zimmermann-Kogadeeva

Lab MattersPeople & Perspectives Maria Zimmermann-Kogadeeva is one of EMBL’s newest group leaders and a computational biologist whose research group applies computational modelling to better understand the metabolism of gut bacteria and their potential to have far-reaching impacts on other organs.

2021

lab-matterspeople-perspectives

24 November 2021 A man standing in front of hedges

Welcome: Tudor Groza

Lab MattersPeople & Perspectives Tudor Groza joins EMBL-EBI as our new Phenomics Team Lead. We found out from Tudor exactly what this new role will entail

2021

lab-matterspeople-perspectives

16 November 2021 Collage showing different species that play an essential part in global food security, including cattle, pollinators and plants

Can data help feed a hungry world?

Science & Technology How genomics, open data, and multidisciplinary science can improve food security.

2021

sciencescience-technology

15 November 2021 3D visualization of the vascularized placenta barrier model on-a-chip.

Building a 3D placenta on a chip

Lab MattersScience & Technology A new model could serve as a platform to investigate critical placenta barrier phenomena, including defence against bacteria, viruses, and parasites.

2021

lab-mattersscience-technology

13 November 2021 close-up of 3 birds

EMBL alum takes DNA sequencing to the field

Science & Technology EMBL alum Lara Urban has developed mobile DNA approaches to monitor impacts upon biodiversity in remote areas of New Zealand and elsewhere.

2021

alumniscience-technology

12 November 2021 Pia Lavriha and Anna Steyer look at cryo-electron microscopic images on a computer screen.

EMBL Imaging Centre welcomes first external user

Lab MattersScience & Technology Correlative microscopy service enables PhD student from Switzerland to study structure and location of proteins cells use to communicate.

2021

lab-mattersscience-technology

10 November 2021 Logo showing an opened padlock and the words “Data Use Ontology” and biomedical samples in background.

DUO: streamlining access to biomedical datasets

Science & Technology The GA4GH Data Use Ontology (DUO) supports a data authorisation and access framework to streamline consent to use biomedical data

2021

sciencescience-technology

10 November 2021 Graphic representations of different types of bacteria.

Making sense of bacterial DNA data

Science & Technology A vast, curated collection of bacterial genomes is now organised, searchable and open to the community.

2021

sciencescience-technology

9 November 2021 students looking a computer monitor and microscope

New horizons for the EIPP

Lab Matters EMBL's PhD and postdoc programmes evolve to the more multidisciplinary way of doing great molecular biology research.

2021

lab-matters

8 November 2021 A scientist is carefully handling capilars at the P12 beamline at EMBL Hamburg.

EMBL Hamburg trains future generations of life scientists in using SAXS

Lab MattersScience & Technology Each year, EMBL Hamburg’s Svergun Group offers practical EMBO courses and lecture courses on biological small-angle X-ray scattering (SAXS). The courses provide young scientists an opportunity to gain hands-on experience by measuring their own samples, and by exploring different aspects of SAXS…

2021

lab-mattersscience-technology

5 November 2021 A headshot photo of Ken Holmes from July 2021

Ken Holmes

People & Perspectives Ken Holmes, outstanding pioneer of structural biology and founder of EMBL´s Hamburg site, died on 2 November 2021 at the age of 87.

2021

alumnipeople-perspectives

5 November 2021 Three-dimensional rendering of sponge neuroid cells (coloured orange) and sponge digestive cells (coloured green).

More than a gut reaction

Science & Technology What can sponges tell us about the evolution of the brain? Sponges have the genes involved in neuronal function in higher animals. But if sponges don’t have brains, what is the role of these? EMBL scientists imaged the sponge digestive chamber to find out.

2021

sciencescience-technology

28 October 2021 female scientist sits in front of building

Welcome: Svetlana Dodonova

Lab MattersPeople & Perspectives Svetlana Dodonova is one of EMBL's newest group leaders, leading a team of researchers who will study how genetic material is organised inside cells using structural biology approaches.

2021

lab-matterspeople-perspectives

26 October 2021

Science for sustainability

ConnectionsLab Matters The engagement of US and European Big Science facilities

2021

connectionslab-matters

26 October 2021 Photo of researcher using MGnify database

Novel enzymes for a Green Economy

Science & Technology Using metagenomic data to find novel enzymes for plastic degradation and beyond

2021

sciencescience-technology

25 October 2021 A collage of the visuals representing each of the three modules of the eSPC platform.

Biophysics analysis made easy with an online tool

Science & Technology EMBL Hamburg’s Sample Preparation and Characterisation (SPC) Facility has released eSPC, an online platform for analysing data from biophysical experiments. The platform enables the scientific community to analyse data from different experiments without the need to travel.

2021

sciencescience-technology

22 October 2021 Oblong shape with two holes and coloured dots inside, representing phytoplankton cells and nitrogen-fixing bacteria

Analysis and sorting with flow cytometry

Lab MattersScience & Technology A technology around since the ‘60s, flow cytometry has increasing applications. New leadership at EMBL’s flow cytometry facilities is looking to ease use, expand training, and encourage more collaboration.

2021

lab-mattersscience-technology

15 October 2021 In the middle, there are two molecules of pUL21. One is blurred, to represent the molecule’s flexibility. In the background are two neuronal scenes. The one on the left is healthy and has a smooth surface. The one on the right is infected, which is represented by several green viral particles.

How herpes seizes proteins’ means of production

Science & Technology The Graham and Crump groups at the University of Cambridge and the Svergun Group at EMBL Hamburg have discovered a mechanism by which the herpes simplex virus takes control of the molecular machinery of human cells. Their work reveals how a dedicated viral protein hijacks key host proteins, forcing…

2021

sciencescience-technology

13 October 2021 Illustration of a community of bacteria. Pills represent an antibiotic that can be used to treat an infection, and a second drug that could protect many gut bacteria from antibiotics.

Tackling the collateral damage from antibiotics

Science & Technology Researchers from EMBL’s Typas group and collaborators have analysed the effects of 144 antibiotics on the wellbeing of gut microbes. The study improves our understanding of antibiotics’ side effects and suggests a new approach to mitigating the adverse effects of antibiotics therapy on gut…

2021

sciencescience-technology

12 October 2021 Man in white and blue t-shirt in outdoor setting

When ‘good’ cells go ‘bad’

Science & Technology If researchers can identify specifically when good cells go bad, they can potentially understand disease better.

2021

sciencescience-technology

8 October 2021 Logos of Ifremer and EMBL with text: “memorandum of understanding”. Illustrations of marine animals and numbers in the background.

EMBL and Ifremer cooperate to advance ocean sciences

ConnectionsLab Matters The two organisations have signed a memorandum of understanding to support scientific cooperation in the exploration of coastal and oceanic ecosystems.

2021

connectionslab-matters

7 October 2021 students looking a computer monitor and microscope

EMBL welcomes young scientists

Lab Matters This autumn, students begin their PhD in research groups across EMBL’s six sites.

2021

lab-matters

7 October 2021 SARS-CoV-2 and planet Earth are merged together in this illustration

Six Ways to Protect the Planet Against Pandemics*

Science & Technology EMBL will host a conference to look at the state of the pandemic, lessons learned, and ways to improve pandemic preparedness. Here’s a sneak peek into what promises to be another interesting and informative EMBL conference.

2021

eventsscience-technology

5 October 2021 Illustration of a globe with colourful shapes and symbols superimposed.

A cellular atlas of an entire worm

Science & Technology EMBL scientists and colleagues have developed an interactive atlas of the entire marine worm Platynereis dumerilii in its larval stage. The PlatyBrowser resource combines high-resolution gene expression data with volume electron microscopy images.

2021

sciencescience-technology

4 October 2021 Logos of University of Tartu and EMBL with text: “memorandum of understanding”. Illustrations of microorganisms in the background.

EMBL strengthens links with Estonia

ConnectionsLab Matters A memorandum of understanding (MoU) has been signed between EMBL and the University of Tartu, a leading centre of research and training. The MoU aims to strengthen cooperation between EMBL and the life science research community in Estonia.

2021

connectionslab-matters

30 September 2021

New microscopy technique makes deep in vivo brain imaging possible

Science & Technology Scientists in EMBL’s Prevedel Group have developed a pioneering microscopy technique that allows researchers to observe cells hidden within opaque tissues, such as live neurons embedded deep in the brain.

2021

sciencescience-technology

29 September 2021 Female scientist working at a biosafety cabinet, wearing a yellow protective gown and black gloves.

Transferable skills

Lab MattersPeople & Perspectives In the lab, Diënty Hazenbrink works with microbes that live in our guts. In her free time, she enjoys wildlife photography. A shared set of skills facilitates both activities.

2021

lab-matterspeople-perspectives

23 September 2021 Pink and blue dominate a blurry image against a black background that is actually a global image of a 30-day-old Octopus vulgaris

The secret life of baby octopuses

Science & Technology Some of the most amazing creatures live in the deep blue sea. The Mesoscopic Imaging Facility (MIF) at EMBL Barcelona was recently involved in studying one unique feature of the octopus: the ephemeral structures on the surface of their skin called Kölliker’s organs.

2021

sciencescience-technology

22 September 2021 Logos of EMBL and Helmholtz Association on white background, over a green-and-blue pattern in the background.

EMBL and Helmholtz Health join forces

ConnectionsLab Matters EMBL and Helmholtz Association have signed a memorandum of understanding. The expanded collaboration of both institutions will focus on research related to health.

2021

connectionslab-matters

17 September 2021 Artistic representation of the complex cell circuit forming the retina

Vision unveiled: new roles for the retina in visual processing

Science & Technology EMBL scientists have found evidence of an unexpected role for retinal cells in pre-processing visual information; their results provide potential opportunity for future prosthetic visual aids.

2021

research-highlightssciencescience-technology

15 September 2021 A dark blue classic star map view is overlaid upon scientific data

Charting a multi-omic universe

Science & Technology A research collaboration used machine learning to map tumour molecular make-up, potentially paving way to more customised cancer treatment.

2021

sciencescience-technology

9 September 2021 Portrait of former EMBL Director General Iain Mattaj

German Cross of Merit for former EMBL Director General

EMBL Announcements Former EMBL Director General Professor Iain Mattaj was awarded the German Cross of Merit (‘Verdienstkreuz 1. Klasse des Verdienstordens der Bundesrepublik Deutschland’) at a ceremony held at EMBL Heidelberg on 9 September 2021.

2021

alumniembl-announcements

9 September 2021 A student in front of a computer watches a scientist working in a laboratory

New horizons for virtual learning

Lab Matters EMBL's science education department makes the latest scientific research more accessible for teachers and students.

2021

eventslab-matters

8 September 2021 Illustration of two halves of a pill, which releases chemical molecules that are taken up by gut bacteria in the vicinity.

Common medications accumulate in gut bacteria

Science & Technology A new collaborative study led by EMBL group leaders Kiran Patil, Nassos Typas, and Peer Bork has found that common medications accumulate in human gut bacteria. This process reduces drug effectiveness and affects the metabolism of common gut microbes, thereby altering the gut microbiome.

2021

sciencescience-technology

7 September 2021 Close up of the interior of a light-sheet microscope, featuring optical equipment and a transparent cube.

A flip book for biological systems

Science & Technology In the Mesoscopic Imaging Facility (MIF) at EMBL Barcelona, researchers study the details of biological systems in the context of organs, body parts, or entire organisms. This image shows OPTiSPIM1, one of the custom light-sheet microscope setups available at the facility.

2021

sciencescience-technology

6 September 2021 Cells organised according to their transcript data changing to the seqFISH mouse embryo map.

The Spatial Mouse Atlas: new insights into cell fate

Science & Technology Researchers have combined spatial gene expression information with single-cell genomics data to create a high-resolution atlas of mouse organogenesis.

2021

sciencescience-technology

20 August 2021 Liz Duke in front of the PETRA III synchrotron.

Welcome: Liz Duke

Lab MattersPeople & Perspectives The new team leader at EMBL Hamburg talks about her plans to establish biological X-ray imaging and high-throughput tomography.

2021

lab-matterspeople-perspectives

12 August 2021 Edith Heard's photo portrait in a circle in the middle of the image.

Edith Heard elected to the German National Academy of Sciences Leopoldina

EMBL AnnouncementsLab Matters EMBL Director General Edith Heard has been elected a member of the German National Academy of Sciences Leopoldina. Her admission to the ‘Human Genetics and Molecular Medicine’ section recognises her outstanding professional contributions to science.

2021

embl-announcementslab-matters

10 August 2021 Scientist working on an instrument of the MASSIF-1 beamline

MASSIF-1 beamline in Grenoble supports COVID-19 drug discovery

Lab MattersScience & Technology MASSIF-1, run jointly by EMBL Grenoble and the ESRF, is a beamline for macromolecular crystallography. It is used by the research community to study the 3D structure of proteins, which is important for drug development.

2021

lab-mattersscience-technology

4 August 2021 Head shot of male scientist

Supporting EMBL and fundamental research

People & Perspectives EMBL alumnus Angus Lamond reflects on the process of translating the importance of fundamental research – to EMBL and wider society.

2021

alumnipeople-perspectives

3 August 2021 illustration of health care providers around a big heart

All heart

Science & Technology A community of scientists is looking at the estimated three billion heart muscle cells in a human heart to better understand heart disease.

2021

alumniscience-technology

29 July 2021 Oblong shape with two holes and coloured dots inside, representing phytoplankton cells and nitrogen-fixing bacteria

What lies beneath: the building blocks of life

Science & Technology Analysis of more than 2 million images has boosted understanding of ocean microbes, shedding light on the distribution of nitrogen-fixers at a global level

2021

sciencescience-technology

20 July 2021 Dark grey bird sitting on a metal lamp post. Grass and rock in the background.

A black redstart visits

Lab Matters Mehdi Khadraoui, a former member of the EMBL Communications team, took this close-up of a black redstart.

2021

lab-matters

13 July 2021 From right to left, Ilaria Piazza and Ken Holmes’ portraits are side by side in circles on a greenish background

EMBL Alumni Awards 2021

People & Perspectives EMBL alumni Ilaria Piazza and Ken Holmes have been recognised for their outstanding contributions, and will receive their awards as part of the celebrations for EMBL World Alumni Day.

2021

alumnipeople-perspectives

12 July 2021 Close-up illustration of the Kinesin-1 protein, intertwined with the aTm1 protein in a helix, next to loopy mRNA molecules.

A model of cooperation for transporting mRNA

Science & Technology EMBL scientists generate a high-resolution crystal structure of the Kinesin-1/aTm1 transport complex in the fruit fly.

2021

sciencescience-technology

9 July 2021 Melissa Graewert stands in front of steely machine

From antibodies to nanoplastics

Science & Technology EMBL’s Melissa Graewert and colleagues are taking a structural biologist’s approach to better understanding nanoplastic particles.

2021

sciencescience-technology

8 July 2021 Two men stand outside in front of a building, holding a document and looking at it.

A hidden medal

People & Perspectives We all like a story about rediscovering treasures, right? Well, that’s just what happened recently at EMBL Grenoble!

2021

alumnipeople-perspectives

5 July 2021

Welcome: Sarah Dyer

Lab MattersPeople & Perspectives EMBL welcomes Sarah Dyer, the new Non-Vertebrate Genomics Team Leader at EMBL-EBI.

2021

lab-matterspeople-perspectives

2 July 2021 Portrait photo of a man in front of trees on a balcony

New head for EMBL’s Developmental Biology Unit

EMBL AnnouncementsLab Matters Dr Alexander Aulehla has been appointed the new Head of EMBL’s Developmental Biology Unit, and will take up the role starting in July 2021.

2021

embl-announcementslab-matters

23 June 2021 Bright blue oblong shape with white hairs on surface on black background.

Starlet sea anemone

Science & Technology EMBL PhD student Anniek Stokkermans captured this side view of a Nematostella vectensis larva during this transition, using instrumentation in the Advanced Light Microscopy Facility at EMBL Heidelberg.

2021

picture-of-the-weekscience-technology

22 June 2021 Woman stands at brown railing in front of trees

Welcome: Anna Erzberger

Lab MattersPeople & Perspectives Anna Erzberger, one of EMBL’s newest group leaders, will provide unique perspective as a theoretical biological physicist.

2021

lab-matterspeople-perspectives

17 June 2021 Three researchers surround microscopy equipment in a dark room with red lighting.

Illuminating protein complexes in cells

Lab MattersPeople & Perspectives EMBL group leaders Julia Mahamid, Anna Kreshuk & Jonas Ries awarded Chan Zuckerberg Initiative grant to advance what we see inside cells.

2021

lab-matterspeople-perspectives

16 June 2021 Microscopy images of bacteria against a backdrop of a crowd of humans.

How our gut microbiome changes over time

Science & Technology Researchers investigate how external factors can influence the persistence of microbe species in the human gut

2021

sciencescience-technology

15 June 2021 Small star-like objects are scattered throughout a black background

Twinkle, twinkle, little nuclear pore complex

Science & Technology As perfect as a summer night sky, these nuclear pores help calibrate a customised super-resolution microscope in EMBL’s Ries group.

2021

picture-of-the-weekscience-technology

9 June 2021 R2DT software for RNA structures

Visualising RNA structures using R2DT

Science & Technology New software enables scientists to visualise RNA secondary structures using the world’s largest RNA structure dataset.

2021

sciencescience-technology

8 June 2021 Two scientists in lab coats working on an instrument in the lab.

EMBL external research community survey

Lab Matters EMBL is conducting an Impact Assessment of our experimental services to understand the value these services have for our external user community. If you have accessed EMBL experimental services at one or more of our facilities to support the conduct of your research, we would like to hear from you.

2021

lab-matters

8 June 2021 Purple, blue and yellow dots on a black background.

Dream team

Science & Technology At EMBL, we have many dream teams – groups of individuals who support each other, innovate, and work together. One of those dream teams bridges two core facilities at EMBL Rome.

2021

picture-of-the-weekscience-technology

4 June 2021 Man in white shirt and blue jeans standing on a terrace in front of trees, facing the camera.

The power of community

Lab MattersPeople & Perspectives EMBL Director Matthias Hentze describes the Environmental Research Initiative: a community effort to solve global environmental challenges.

2021

lab-matterspeople-perspectives

3 June 2021 Illustration of a rocky coastline with sailing boat, mountains, underwater organisms, bridge and factory in the background.

Living laboratories

Science & Technology Under the innovative Planetary Biology research theme, EMBL scientists aim to understand life in the context of its environment.

2021

sciencescience-technology

1 June 2021 Two purple and white spheres against dark background.

Nuclear twins

Science & Technology Captured by EMBL postdoc Arina Rybina, these ‘nuclear twins’ are two daughter nuclei straight after division of a HeLa cell.

2021

picture-of-the-weekscience-technology

31 May 2021 Collage showing injection needle, coronavirus and vaccine vials

Genomic surveillance of SARS-CoV-2 in England

Science & Technology The largest in-depth analysis of genomic surveillance data mapping out the dynamics of 62 lineages of the SARS-CoV-2 virus.

2021

sciencescience-technology

25 May 2021 Microscope image of an engineered human blood vessel, featuring individual cells outlined in pink with blue nuclei.

Barriers against malaria

Science & Technology The Bernabeu Group aims to increase our knowledge of cerebral malaria, using in vitro engineered networks of human blood vessels and brain cells.

2021

picture-of-the-weekscience-technology

21 May 2021 Image of a mosquito on a clear surface

EMBL scientists support malaria research

Science & Technology EMBL scientists support research on malaria by providing freely available data resources and using innovative experimental approaches. Our Course and Conference Office facilitates the exchange of knowledge in the field by hosting the annual BioMalPar conference.

2021

sciencescience-technology

20 May 2021 Male scientist in white coat is laboratory setting

Michael Zimmermann receives FEBS Anniversary Prize

EMBL AnnouncementsLab Matters The Gesellschaft für Biochemie und Molekularbiologie has awarded a FEBS Anniversary Prize to Michael Zimmermann for his gut microbiome research.

2021

embl-announcementslab-matters

18 May 2021 Three bright red orange objects in shapes approximating circles with some protrusions are set against a black background.

Cellular fireball or immune cells?

Science & Technology The EMBL Picture of the Week features a series of Jurkat T cells during different stages of the activation process.

2021

picture-of-the-weekscience-technology

17 May 2021 A selection of screenshots featuring participants at the Emerging Infectious Disease conference.

How can we prepare for future pandemics?

Connections Leading international experts gathered to showcase progress in the fight against COVID-19 and share lessons for the future.

2021

connectionsevents

10 May 2021 The image shows Inserm and EMBL logos and illustrates the memorandum of understanding signed between both institutions.

EMBL and Inserm to join forces

ConnectionsLab Matters A memorandum of understanding has been signed between EMBL and Inserm to strengthen their scientific cooperation.

2021

connectionslab-matters

5 May 2021 Woman sits at desk in office setting

After the lecture: Zehra Sayers

People & Perspectives Zehra Sayers explains what makes the SESAME synchrotron special, why we should not fear failure, and why curiosity is her biggest driver.

2021

alumnipeople-perspectives

28 April 2021 Artistic representation of brain and DNA

Uniting strengths to expand research

ConnectionsLab Matters The European Molecular Biology Laboratory and the Italian Institute of Technology have signed an agreement to expand the scope of their collaboration to include areas of mutual interest and in the context of EMBL’s 2022-2026 Programme “Molecules to Ecosystems”.

2021

connectionslab-matters

27 April 2021 Three irregular shapes, made up of green, blue, red and pink speckles, are set against a black background.

SARS-CoV-2 curtails immune response in the gut

Science & Technology EMBL scientists, together with collaborators from Heidelberg University, have provided further evidence of the gut’s role in COVID-19.

2021

sciencescience-technology

27 April 2021 Microscope image of liver cells, highlighted in various colours.

Painting liver cells

Science & Technology A page from a biologist’s colouring book? EMBL’s new interior wall design? Not quite – a bunch of liver cells, grown in the lab so that scientists can learn about fatty liver disease, or steatosis.

2021

picture-of-the-weekscience-technology

26 April 2021 Portrait photo of Edith Heard, EMBL Director General

EMBL DG joins WHO Science Council

ConnectionsLab Matters Edith Heard has been appointed to a new World Health Organization advisory council.

2021

connectionslab-matters

20 April 2021 Black-and-white sphere with coronavirus spike protein structures and a two-layered ring of virus membrane superimposed.

Variations on a spike

Science & Technology What does coronavirus’s spike protein look like in 3D? EMBL scientists and colleagues used cryo-electron tomography and molecular dynamics simulations to find out.

2021

picture-of-the-weekscience-technology

13 April 2021 Picture showing MD3, the micro-diffractometer developed by the Instrumentation team, installed at one of the EMBL Hamburg's beamline. Credits: Kinga Lubowiecka/EMBL

Structural biology at EMBL: driving technology development

Lab MattersScience & Technology Florent Cipriani, who recently retired as Head of the Instrumentation Team after a long career at EMBL Grenoble, is one of the pioneers of instrumentation development in this field.

2021

lab-mattersscience-technology

13 April 2021 EMBL Heidelberg's main building, the top of the façade lit up by sunlight.

Morning sun

Lab Matters Throwback to June 2014: While EMBL Heidelberg’s main entrance is still in the dark, the well-known EMBL logo is already lit by the morning sun.

2021

lab-matterspicture-of-the-week

8 April 2021 Genetics of ageing

Linking genetics and age-related diseases

Science & Technology Researchers have used human medical and genetic data from UK Biobank to investigate the genetics of age-related diseases

2021

sciencescience-technology

7 April 2021 Man standing next to painting

Welcome: Matthew Hartley

Lab MattersPeople & Perspectives The challenges and opportunities when setting up a global archive for bioimages

2021

lab-matterspeople-perspectives

6 April 2021 A model of Glycine Transporter 1, which is located in the cell membrane. In its lower-middle part, it is bound by its inhibitor, which is a much smaller molecule. At its top, Glycine Transporter 1 is bound by a synthetic mini-antibody, called a sybody.

New perspectives for treating psychiatric disorders

Science & Technology Scientists have determined the structure of Glycine Transporter 1. The finding could open new avenues for developing therapeutics for psychiatric disorders

2021

sciencescience-technology

6 April 2021 Sea anemone polyp seen through a microscope, cell nuclei and muscles highlighted.

A multifunctional mouth

Science & Technology This image of a young Nematostella vectensis polyp shows two of the characteristic tentacles as well as the gaping mouth of the animal.

2021

picture-of-the-weekscience-technology

30 March 2021 Ana Boskovic sitting in her office

Welcome: Ana Boskovic

Lab MattersPeople & Perspectives The new group leader at EMBL Rome will study how embryos can inherit non-genetic information from their parents that causes stable and heritable effects

2021

lab-matterspeople-perspectives

30 March 2021 A close-up photo of a shiny droplet of liquid that has been placed into one of the wells of a crystallisation plate.

Droplet beauty

Science & Technology Scientists at EMBL Hamburg use droplets of protein solution to grow protein crystals. By exposing the crystals to X-rays, they are able to determine the protein’s molecular structure.

2021

picture-of-the-weekscience-technology

23 March 2021 Man pouring water in a glass bottle to make coffee.

Green coffee at EMBL

Lab Matters The cafeteria at EMBL Heidelberg now offers espresso and cappuccino with a more intense flavour and which are produced in a ‘green’ way.

2021

lab-matterspicture-of-the-week

16 March 2021 Pink blooming tree in front of functional building.

Italian Spring

Lab Matters EMBL’s site in Monterotondo has recently been blessed with blue skies and sunshine, leading to trees blooming early on campus.

2021

lab-matterspicture-of-the-week

11 March 2021 Man in black t-shirt and jeans wearing glasses sits in front of two computer screens.

From mRNA researcher to BioNTech manager

People & Perspectives EMBL alumnus Pawel Masiewicz has transferred skills and experience gained at EMBL to oversee starting materials for mRNA vaccine development.

2021

alumnipeople-perspectives

9 March 2021 Wolfgang Huber faces the camera smiling

Wolfgang Huber becomes ISCB Fellow

EMBL AnnouncementsLab Matters The contribution of EMBL Group Leader and Senior Scientist Wolfgang Huber has been recognised by the International Society for Computational Biology

2021

embl-announcementslab-matters

9 March 2021 This photo shows the European Photon and Neutron (EPN) science campus on the peninsula at the confluence of the Isère and Drac rivers, where EMBL Grenoble is located.

Touch of springtime in Grenoble

Lab Matters This photo shows the European Photon and Neutron (EPN) science campus where EMBL Grenoble is located. A delightful spring breeze in the air melts the last remaining patches of snow in the mountains.

2021

lab-matterspicture-of-the-week

8 March 2021 Head shot of female social scientist with blond curly hair and blue/grey eyes.

After the lecture: Tracey Brown

Lab Matters Tracey Brown from Sense about Science shares her thoughts on the need to empower women to share and access scientific information.

2021

lab-matters

8 March 2021 Two femail scientists facing each other in discussion.

EMBL prepares women postdocs for leadership

Lab Matters Members of EMBL’s Equality, Diversity and Inclusion Committee explain how EMBL is choosing to challenge through its LEAP mentoring programme.

2021

lab-matters

4 March 2021

Induced pluripotent stem cells reveal causes of disease

Science & Technology Scientists in the Stegle group and colleagues have studied induced pluripotent stem cells from around 1,000 donors to identify correlations between individual genetic variants and altered gene expression. They linked more than 4,000 of the genetic variants responsible for altered expression…

2021

sciencescience-technology

2 March 2021 Microscopy image of stem cells in bone marrow

New avenues for eradicating cancer

Science & Technology A new method has the potential to boost international research efforts to find drugs that eradicate cancer at its source.

2021

sciencescience-technology

2 March 2021

Sleeping beauty

Science & Technology Like caterpillars turning into beautiful butterflies, fruit fly larvae have to go through metamorphosis to finish their development. However, despite the fruit fly Drosophila melanogaster being one of the best studied model organisms in biology, comparatively little attention has been given to this…

2021

picture-of-the-weekscience-technology

26 February 2021 Woman with long brown hair stands in front of snow scene with arms crossed in front of her.

Welcome: Sinem Saka

Lab MattersPeople & Perspectives As one of EMBL’s newest group leaders, Sinem Saka will combine multiple technologies, such as microscopy and single-cell omics, to solve biological puzzles.

2021

lab-matterspeople-perspectives

23 February 2021 Two women's portraits are in circles on a greenish background

Reflecting on allyship as women in science

Lab Matters Being a woman in science takes allies, not just great science. Here, EMBL’s L’Oréal–UNESCO Fellows talk about support networks.

2021

lab-matters

23 February 2021 Greyscale image of a cell with its internal components visible

Seeing through a cell

Science & Technology Liang Xue used cryo-electron tomography to capture this detailed image of a Mycoplasma pneumoniae cell.

2021

picture-of-the-weekscience-technology

22 February 2021

Feldberg Prize for Anne Ephrussi

EMBL AnnouncementsLab Matters Anne Ephrussi has been awarded the German Feldberg Prize 2022 in recognition of her outstanding research.

2021

embl-announcementslab-matters

22 February 2021 A scientist (only their hand is visible) inserting a 96-well plate into a sample dispensing device in the Sample Preparation and Characterisation Facility in Hamburg.

SPC Facility in Hamburg supports a new pan-European consortium

ConnectionsLab Matters The Sample Preparation and Characterisation (SPC) Facility at EMBL Hamburg is one of the founding members of the Molecular-Scale Biophysics Research Infrastructure (MOSBRI). Within this new European initiative, the SPC Facility will offer services related to membrane proteins, protein complexes,…

2021

connectionslab-matters

19 February 2021 New group leader Gautam Dey looks smiling towards the camera,

Welcome to EMBL: Gautam Dey

Lab MattersPeople & Perspectives Gautam Dey is fascinated by the evolutionary origins of the nucleus, and is looking forward to making the most of EMBL's infrastructure.

2021

lab-matterspeople-perspectives

18 February 2021 Phages invading gut bacteria.

The thousands of viruses living in your gut

Science & Technology Scientists identify more than 140 000 virus species in the human gut; more than half have never been seen before

2021

sciencescience-technology

17 February 2021 Illustration of a pink capsule passing through a grey pore in a yellow membrane.

A new piece of the HIV infection puzzle explored

Science & Technology Researchers from EMBL and Heidelberg University Hospital combine high-resolution imaging to observe the infection process in cell nuclei, opening the door for new therapeutics.

2021

sciencescience-technology

16 February 2021 Microscopy images of coronavirus-infected cells in blue and red, arranged on a clockface. Illustrations of virus particles.

Finding coronavirus’s helper proteins

Science & Technology A team of EMBL scientists and colleagues have analysed how the novel coronavirus affects proteins in human cells. They identified several human proteins as potential drug targets to prevent viral replication.

2021

sciencescience-technology

16 February 2021 An assembly of proteins in an enzyme, presented in a cartoon style.

Cellular modern art

Science & Technology This week's Picture of the Week, which could also be a masterpiece of modern art, shows the enzyme RNA polymerase III, an assembly of 17 individual proteins combined into this complex structure.

2021

picture-of-the-weekscience-technology

11 February 2021 Logos of EMBL and the EMBRC.

Understanding Earth’s oceans together

ConnectionsLab Matters EMBL and EMBRC have signed a memorandum of understanding for increased scientific collaboration.

2021

connectionslab-matters

11 February 2021 Maria-Theresa Licka holding a smartphone displaying an app she developed. Vineyards, houses and hills in the background.

Coding between the vines

Lab Matters EMBL Teen Maria-Theresa Licka shares how female scientists guided & inspired her to develop an app to ID vine disease.

2021

lab-matters

9 February 2021 An artistic representation of how bioinformatics allows study of the SARS-CoV-2 infection process. On the left, coronaviruses are approaching a human face contour. On the right, protein structures and a network of connections represent bioinformatic analysis.

Protein sequences provide clues to how SARS-CoV-2 infects cells

Science & Technology Researchers at EMBL Heidelberg have identified sequences in human proteins that might be used by SARS-CoV-2 to infect cells. They have discovered that the virus might hijack certain cellular processes, and they discuss potentially relevant drugs for treating COVID-19.

2021

sciencescience-technology

9 February 2021 Roshni Mooneeram, EMBL Equality, Diversity and Inclusion Officer, strikes the #ChooseToChallenge pose with her hand high, pledging to call out bias and actively question stereotypes.

Opinion: Allyship and Women in Science

Lab Matters Roshni Mooneeram discusses what Equality, Diversity and Inclusion (EDI) is to her, and what the meaning of allyship is.

2021

lab-matters

9 February 2021 Crystal cubes seen through a microscope

Purity, beauty, and perfection

Science & Technology The regular structures of crystals are a source of inspiration and fascination to us humans. While the crystals in this picture were not grown in nature, but instead by Petra Drncova from EMBL Grenoble, they share the same attributes as those found in nature.

2021

picture-of-the-weekscience-technology

8 February 2021 Illustration of a laboratory flask to the left of a microscope against an orange/grey background with a zoomed-in cut-out of the microscope view, which is colourful molecules.

A better look at a human RNA polymerase

Science & Technology New EMBL research shows where & to what degree a component of cellular machinery known as RNA Pol III is mutated and becomes problematic.

2021

sciencescience-technology

5 February 2021 Artistic representation of the structure of the three proteins forming Integrator’s catalytic core.

At the core of the Integrator complex

Science & Technology A new paper from the Galej group at EMBL Grenoble describes the structure of key parts of the Integrator complex, involved in gene expression.

2021

sciencescience-technology

2 February 2021 A bacterial cell with the parts needed for information flow from DNA to messenger RNA to protein highlighted in different colours.

The central dogma of molecular biology

Science & Technology This colourful image shows biological information flow in action: It’s a supramolecular assembly of DNA, RNA and proteins, observed directly inside a bacterial cell while turning genetic information into protein.

2021

picture-of-the-weekscience-technology

29 January 2021 Flags of EMBL, Italy and CNR

Strengthening collaborations in Italy

ConnectionsLab Matters EMBL and CNR have signed a memorandum of understanding to strengthen scientific cooperation. The agreement will foster collaborative projects and integrate them within the European and global scientific landscape.

2021

connectionslab-matters

27 January 2021 Nicoletta Petridou looks towards the camera smiling, whilst standing in a science laboratory

Welcome: Nicoletta Petridou

Lab MattersPeople & Perspectives New group leader Nicoletta Petridou explains her fascination with the complexity of early embryo development, and how the interdisciplinary nature of EMBL will aid her research.

2021

lab-matterspeople-perspectives

26 January 2021 Two X-ray mirrors installed in the macromolecular crystallography beamline P14 at EMBL Hamburg. The mirrors are visible in the photo as dark rectangular crystal blocks, with two metal holders supporting the crystals in a stress-free position. The mirrors are inserted into a vacuum-compatible stainless steel vessel.

Mirror, mirror

Science & Technology Scientists at EMBL Hamburg use specially designed mirrors to reflect and focus X-ray beams onto tiny crystals made of proteins or other biological molecules.

2021

picture-of-the-weekscience-technology

20 January 2021

The SARS-CoV-2 B.1.1.7 lineage

Science & Technology A note on the coronavirus variant B.1.1.7, which has first been described in the U.K. and has spread to 57 countries. The note summarises epidemiological information about the spread of B.1.1.7 in the U.K. collated and in part conducted by researchers from EMBL-EBI.

2021

sciencescience-technology

20 January 2021 Logos of EMBL and the DKFZ

DKFZ and EMBL intensify cooperation

ConnectionsLab Matters EMBL and the German Cancer Research Center in Heidelberg are increasing their already existing collaborations with a Memorandum of Understanding between the two institutions.

2021

connectionslab-matters

19 January 2021 3D rendering of a human cell, attacked by a virus.

Cell under attack

Science & Technology It’s almost a year since the coronavirus outbreak was declared a pandemic, affecting all our lives. While the virus continues its grip on the world, scientists are understanding it better and better, increasing our knowledge about it and opening up new ways to fight it.

2021

picture-of-the-weekscience-technology

18 January 2021 man wearing sweater and glasses stands in front of snow and glassy building

Welcome: Timo Zimmermann

Lab MattersPeople & Perspectives The EMBL Imaging Centre is scheduled to open in 2021 with Timo Zimmermann as Team Leader for advanced light microscopy technology development and service provision.

2021

lab-matterspeople-perspectives

15 January 2021 young man with beard and mustache stands in front of window with blurry background

Welcome: Olivier Duss

Lab MattersPeople & Perspectives One of EMBL’s newest group leaders, Olivier Duss, will explore how RNA folds into functional structures and how it works with proteins to control a diverse range of activities in the cell.

2021

lab-matterspeople-perspectives

14 January 2021 An electron microscopy photo shows two bacterial cells surrounded by several white fibrils of the amphibian peptide.

Toadlet peptide transforms into a deadly weapon against bacteria

Science & Technology Researchers at the Technion – Israel Institute of Technology and EMBL Hamburg, in collaboration with scientists in Israel and Spain, have discovered remarkable molecular properties of an antimicrobial peptide from the skin of the Australian toadlet. The discovery could inspire the development of…

2021

sciencescience-technology

12 January 2021 Three images showing close-ups of different EMBL facilitites.

EMBL becomes newest Instruct Centre

ConnectionsLab Matters EMBL’s sites in Grenoble, Hamburg, and Heidelberg form the newest Instruct Centre. The new centre offers users access to a broad range of state-of-the-art facilities.

2021

connectionslab-matters

12 January 2021 A metallic tool.

Homage to a vital tool

Science & Technology Structural biologists want to study proteins at the atomic level. The device shown in this Picture of the Week is essential for this.

2021

picture-of-the-weekscience-technology

5 January 2021 colourful abstract photo with brilliant yellow-green streaks interspersed with shiny pink yellow and blue dots randomly displayed in photo

It’s like a party in your brain

Science & Technology Fluorescent dyes light up a cellular community of neurons and brain immune cells (microglia), which were derived from stem cells.

2021

picture-of-the-weekscience-technology

4 January 2021 photo of white nodule that is a kefir grain sitting in front of a milk bottle with two inset images -- one looks like yellow and tan circles, and the other is animated versions of the kefir grains

In kefir, microbial teamwork makes the dream work

Science & Technology Researchers discovered the dominant species of bacteria in kefir grains cannot endure without other species that help the 'team' survive.

2021

sciencescience-technology

22 December 2020 Eulalia clavigera. Photo credit: Marine Biological Association

Darwin Tree of Life: looking back on 2020

Science & Technology Despite restrictions, 2020 has been a busy year for the Darwin Tree of Life Project. We take a look at some of this year’s achievements and highlights.

2020

sciencescience-technology

22 December 2020

Cells in the holiday spirit

Science & Technology It is that time of year to get into the holiday spirit, prepare for some time at home and relax after a strange and stressful year. Even the cells in our Picture of the Week are getting into the holiday spirit, forming this colourful Christmas tree.

2020

picture-of-the-weekscience-technology

18 December 2020

Stronger together

Science & Technology Gene activation requires the cooperative activity of multiple transcription factors. Until now, the mechanism used by these factors to coordinate their actions has been poorly understood. EMBL’s Krebs group presents a DNA footprinting method that makes it possible to determine whether…

2020

sciencescience-technology

15 December 2020 Snowy mountains behind functional buildings. The Moon is up in the sky.

First powder over EMBL Grenoble

Lab Matters The first snowflakes have fallen on the Vercors Mountains, right behind the EMBL Grenoble building, and an almost full moon is showing up during a sunny morning.

2020

lab-matterspicture-of-the-week

11 December 2020 Woman with glasses wearing a parka stands in the snow outside a building at EMBL

EMBL Scientific Visitor Programme opens eyes and doors

EMBL AnnouncementsLab Matters Facilitated by EMBL’s Scientific Visitor Programme in 2019, Silvia Dias Almeida spent a year in the Diz-Muñoz group, helping solidify her career plans and set her up for a competitive PhD programme in biomedical imaging.

2020

embl-announcementslab-matters

9 December 2020 Illustration of a rod-shaped bacterial cell, superimposed on a red and blue background.

Heating proteins to understand how genes work

Science & Technology A new paper from EMBL’s Savitski team and Typas group describes their work on E. coli and how it brings a greater understanding of the way genes function and interact.

2020

sciencescience-technology

8 December 2020 Windowed façade reflecting leafless trees.

Clear views

Lab Matters With the external scaffolding removed, another step in the construction of the EMBL Imaging Centre is complete. Now we get a first glimpse of the final look of this stunning building.

2020

lab-matterspicture-of-the-week

7 December 2020 Female scientist stands in front of electron microscope that is taller than she is

Seeing deeper inside cells

Science & Technology While cryo-electron tomography (cryo-ET) was first envisioned in 1968, the advances the Mahamid group are bringing to this 3D method for studying molecules directly inside cells are new, and are likely to greatly expand its use.

2020

sciencescience-technology

4 December 2020 Haemoglobin protein structure shown over a matrix symbolising artificial intelligence

Solving the protein structure puzzle

Science & Technology How artificial intelligence can help us solve the mysteries of the protein universe

2020

sciencescience-technology

2 December 2020 Dark purple image with flashes of orange, gold, pink and paler purple that look a bit like lightning with a small sun-like image in the upper right section of the image

Chan Zuckerberg Initiative recognises EMBL scientists

EMBL AnnouncementsLab Matters The Chan Zuckerberg Initiative has recognised four EMBL researchers with their most recent awards, showing how tech trailblazers are integral to advancing science and medicine.

2020

embl-announcementslab-matters

2 December 2020 The image is a green coloured cell, with a wild and textured surface which is composed of many different shapes and shadows.

Scratching the surface on cell differentiation

Science & Technology Scientists in the Diz-Muñoz group at EMBL Heidelberg are working to build understanding of the role that mechanical properties play in affecting cell behaviour – a young and rapidly developing field of study. They have developed and successfully used a highly specialised technique to manipulate…

2020

sciencescience-technology

2 December 2020 Curly-shaped trypanosomes, grey with bright specks of green fluorescent protein, against a grey background.

Tackling tropical diseases

Science & Technology Members of the EMBL community are working to improve our understanding of the parasites that cause malaria and sleeping sickness

2020

sciencescience-technology

1 December 2020 The image shows the beamline P12 at EMBL Hamburg. In the centre, several cylindrical elements are connected into a pipe-like structure. In the front, it is connected to a white box-shaped device, and several smaller devices and cables visible around. There is also a grid visible around the beamline.

EMBL facilities support development of RNA vaccines

Science & Technology Biotechnology company BioNTech and Johannes Gutenberg University Mainz conduct collaborative research with EMBL scientists at the beamline P12 in Hamburg

2020

sciencescience-technology

1 December 2020 Rainbow on a cloudy sky above technical buildings.

Rainbow over the Hanseatic city

Lab Matters Hamburg hosts one of EMBL’s six sites. The city is notorious for its windy and rainy weather. Lots of rain also means a high chance of beautiful rainbows!

2020

lab-matterspicture-of-the-week

25 November 2020 The conference key visual shows a variety of species engulfed by fire, reflecting the conference title, ‘Our House Is Burning: Scientific and Societal Responses to Mass Extinction’.

Science and society: global youth activism

People & Perspectives At EMBL’s Science and Society conference, Ugandan campaigner Vanessa Nakate spoke about the need to take action on climate change.

2020

eventspeople-perspectives

24 November 2020 Red loops on a black background are dotted with bright red flecks and pale blue ovals as part of a confocal microscope image of bone marrow cells.

A loopy baseline

Science & Technology Studying cancers means also knowing what healthy cells look like. In this case, mesenchymal stromal cells (MSCs) from healthy bone marrow are a bit ‘loopy’.

2020

picture-of-the-weekscience-technology

23 November 2020 Tube-like structures of a cell at sub-cellular level in red and grey.

Replication cycle of SARS-CoV-2 in 3D

Science & Technology Researchers have studied SARS-CoV-2 replication in cells and obtained detailed insights into the alterations induced in infected cells. This information is essential to guide the development of urgently needed therapeutic strategies for suppressing viral replication and induced pathology.

2020

sciencescience-technology

23 November 2020

Statement on recent paper on mentorships in academia

EMBL AnnouncementsLab Matters EMBL’s Eileen Furlong, Chair of the Equality and Diversity Committee and Head of the Genome Biology Unit, responds to the recent Nature Comms paper on the potential effects of mentor–mentee relationships.

2020

embl-announcementslab-matters

20 November 2020 The Reichstag building (left) and Paul-Löbe-Haus (right) in Berlin, as seen in daylight from across the Spree river.

Sharing our vision for the future

ConnectionsLab Matters EMBL Director General Edith Heard introduced EMBL’s future plans during a parliamentary event at the Paul-Löbe-Haus of the German Bundestag in Berlin. She shared examples of EMBL’s research and outlined how EMBL’s activities will develop.

2020

connectionslab-matters

17 November 2020 Internal structures of the lower portion of a mouse lung display as a conical shape, displaying a variety of brilliant colours.

ARISE fellowship programme readying for applications

Lab Matters Ever-evolving technology and related budgetary, regulatory, and management challenges prompted EMBL to establish its new ARISE fellowship programme, which begins accepting applicants in December.

2020

lab-matters

17 November 2020 Car parking rooftop with a solar power plant under construction on it.

Solar power

Lab Matters Despite the cold autumn weather, workers are busy on the rooftop of the parking garage at EMBL Heidelberg. The 2176 m² rooftop is getting transformed into a combination of a green roof and a photovoltaic plant. The planted green roof will retain rainwater, while the solar panels – installed in…

2020

lab-matterspicture-of-the-week

10 November 2020 Green coloured brain cells next to a microfluidic network.

Understanding malaria

Science & Technology To help understand cerebral malaria the Bernabeu group has created in vitro engineered networks of human blood vessels.

2020

picture-of-the-weekscience-technology

4 November 2020 SARS-CoV-2 is represented as a sphere with spike proteins poking out of its surface, which give it a corona-like appearance. The spike proteins resemble triangular ‘bushes’ with three tips at the top. In the background, a cell surface is visible with ACE2 proteins poking out of it in many places. The virus is about to attach to the cell surface. The sybodies, represented as tiny V-shaped structures, bind to the viral spike proteins at their tips.

Scientists identify synthetic mini-antibody to combat COVID-19

Science & Technology By screening hundreds of sybodies (synthetic mini-antibodies), scientists have identified one that might stop SARS-CoV-2 from infecting human cells. This work, which holds promise for treating COVID-19, was conducted by EMBL Hamburg and collaborators from the Centre for Structural Systems Biology…

2020

sciencescience-technology

3 November 2020 Rainbow above the EMBL building in Heidelberg, surrounded by woods.

Under the rainbow

Science & Technology On autumn days without Heidelberg’s characteristic fog, the woods present themself in beautiful colours. You may even capture a rainbow.

2020

picture-of-the-weekscience-technology

28 October 2020 A brain hovers over a chess board, lines flow from the hypothalamus to the pieces, symbolising control over reactions to an aggressor and territory.

Should I run, or should I not? The neural basis of aggression and flight

Science & Technology Researchers in the Gross group at EMBL Rome have investigated the mechanism behind defensive behaviour in mice. They have identified a specific area of the brain that encodes both spatial and threat cues to drive location-specific defensive responses.

2020

sciencescience-technology

27 October 2020 Microscopic image of a cell, nucleus visible in bright green, cell membrane stained with a purple dye against black background.

Party at the nucleus?

Science & Technology The nucleus of this cell fluoresces in bright green thanks to GFP-labelled nucleoporin proteins. EMBL scientists use engineered nucleoporins as 3D reference standards to improve super-resolution microscopy.

2020

picture-of-the-weekscience-technology

23 October 2020 Futuristic image of deep learning schema superimposed on computer code

Bringing AI out of the black box

Lab MattersScience & Technology Why should researchers make artificial intelligence more transparent and how can they do it?

2020

lab-mattersscience-technology

22 October 2020 An artistic image of colorful wires connected to a could database.

EOSC: shaping Europe’s digital future

ConnectionsLab Matters EMBL’s Rupert Lück is engaged in developing the European Open Science Cloud (EOSC): the infrastructure that will support the future of data sharing and analysis in Europe.

2020

connectionslab-matters

20 October 2020 Open access COVID-19 data sharing

Open data sharing accelerates COVID-19 research

Science & Technology Open access data benefits millions of scientists around the world and is essential for a rapid response to the COVID-19 pandemic.

2020

sciencescience-technology

20 October 2020 Greyscale image of two sheep grazing.

Ecological lawn mowers

Lab Matters In 2012, EMBL used ecological lawn mowers to keep the grass short around the Advanced Training Centre at EMBL Heidelberg.

2020

lab-matterspicture-of-the-week

19 October 2020 Green background with white sphere bearing the logos of the two MoU signors, EMBL and CIML

EMBL forms new collaborations in France

ConnectionsLab Matters EMBL and CIML have signed a memorandum of understanding that will open up new scientific opportunities.

2020

connectionslab-matters