New technique that elucidates how different types of cells are made, could facilitate earlier detection of diseases
Scientists in the Stegle and Marioni groups, in collaboration with scientists at the Babraham Institute and University of Edinburgh, have developed the first single-cell analysis method that allows simultaneously analysis of nucleosome, methylation and transcription. scNMT-seq allows researchers to analyse differences between single cells that could play key roles in both the early stages of life and the first stages of diseases such as cancer.
This image is a composite of lateral pentascolopidial organs, a wing imaginal disc pouch, and an epithelial wound in a Drosophila larva. The organs are arranged here like eyelashes. Cells surrounding an epidermal wound appear as the iris and pupil of this artistic eye.