Edit

Ring of fire

This Picture of the Week is actually more than just one image: it has been composed from thousands of individual super-resolution microscopy images. This composite image, created by Markus Mund in the Ries Group at EMBL Heidelberg, shows the radial organisation of proteins on the cell membrane during endocytosis.

Endocytosis is the cellular process in which substances are brought inside the cell. The material to be transported is surrounded by an area of cell membrane. This membrane buds into the cell to form a vesicle containing the ingested material.

This super-resolution microscopy image by Mund shows how a set of cytosolic proteins guide actin polymerisation locally. Actin patches will generate the mechanical force required to bend the cell membrane and form endocytic vesicles.

In this image, three proteins are stained: Bbc1 in red, Las17 in blue and Sla1 in yellow. Other colours represent the overlap between different rings. Bbc1 and Sla1 confine Las17 to this well defined blue ring, which triggers actin polymerisation.

Credit: Markus Mund/EMBL

If you have a stunning picture of your science, your lab or your site, you can submit it to: mathias.jaeger@embl.de.

Tags: endocytosis, membrane, Picture of the Week, Protein

More from this category

Picture of the week

Throwback to June 2014: While EMBL Heidelberg’s main entrance is still in the dark, the well-known EMBL logo is already lit by the morning sun.

By  Mathias Jäger

EMBL Heidelberg's main building, the top of the façade lit up by sunlight.

EMBLetc.

Read the latest Issues of our magazine - EMBLetc.

Looking for past print editions of EMBLetc.? Browse our archive, going back 20 years.

EMBLetc. archive

Newsletter archive

Read past editions of our monthly e-newsletter

For press

Contact the Press Office
Edit