EMBL Events

21 October - 26 October 2024

Imaging down to single-molecule resolution: STED & MINFLUX nanoscopy

Clara Gürth, Charlotte Kaplan, Marko Lampe, Ulf Matti, Julia Menzel, Sebastian Schnorrenberg

OverviewSpeakers trainers and staffProgrammePractical informationSponsorsMedia kit Overview Course overview The aim of the course is to train microscopy users in different super resolution microscopy methods Stimulated Emission Depletion STED and MINFLUX nanoscopy Both techniques overcome the diffraction limit of light with the help of a donut shaped laser beam thereby achieving... OverviewSpeakers, trainers, and staffProgrammePractical informationSponsorsMedia kit Overview Course overview The aim of the course is to train microscopy users in different super-resolution microscopy methods: Stimulated Emission Depletion (STED) and MINFLUX nanoscopy. Both techniques overcome the diffraction limit of light with the help of a donut-shaped laser beam, thereby achieving resolutions that are impossible with conventional light microscopy.The course combines scientific lectures by experienced researchers from the super-resolution field with hands-on sessions at the different super-resolution microscopes and in the laboratory. Participants will gain a technical understanding of the methods as well as an overview of different application fields and imaging techniques, sample preparation, and data handling for both STED and MINFLUX. After the course, participants can choose the...

23 October 2024

I made my code open - now what? Steps to a thriving open software project

Sharing your code is a good first step towards building open source software but it is not enough to ensure its success This webinar focuses on practical issues to increase impact of open software projects including maintenance community building discoverability project management documentation licensing and user needs Our speakers will share their experience working with the open source code as part of the CAPITAL project open source tool that uses machine learning to identify biological concepts from text and link them to relevant ontologies They will discuss the challenges they have encountered and potential solutions to address these... Sharing your code is a good first step towards building open source software, but it is not enough to ensure its success. This webinar focuses on practical issues to increase impact of open software projects, including maintenance, community building, discoverability, project management, documentation, licensing, and user needs.  Our speakers will share their experience working with the open source code as part of the CAPITAL project - open source tool that uses machine learning to identify biological concepts from text and link them to relevant ontologies. They will discuss the challenges they have encountered and potential solutions to address these.

29 October - 31 October 2024

Managing a bioinformatics core facility

Barbara Etzi

This knowledge exchange workshop is an opportunity for managers of bioinformatics core facilities to learn from EMBL EBI s service teams and from each other These facilities play an essential role in enabling research in the life sciences The landscape is constantly evolving as new research tools emerge as experiments become increasingly data intensive and as their users experimental researchers become more exposed to the power of data driven biology This course will allow participants to share experiences discuss challenges and solutions that they face and plan ways to cope with the ever changing demands raised by the molecular life science field It will include sessions to learn from bioinformatics service providers hear how others have tackled common problems and work together to design core services resource them and measure their impact A limited number or travel bursaries are available Please see the Additional information tab for conditions... This knowledge exchange workshop is an opportunity for managers of bioinformatics core facilities to learn from EMBL-EBI’s service teams, and from each other. These facilities play an essential role in enabling research in the life sciences. The landscape is constantly evolving as new research tools emerge, as experiments become increasingly data intensive, and as their users – experimental researchers – become more exposed to the power of data-driven biology.This course will allow participants to share experiences, discuss challenges and solutions that they face, and plan ways to cope with the ever changing demands raised by the molecular life science field. It will include sessions to learn from bioinformatics service providers, hear how others have tackled common problems, and work together to design core services, resource them, and measure their impact.A limited number or travel...

31 October 2024

Programmatic access to UniProt using Python

UniProt is a comprehensive expert led publicly available database of protein sequence function and variation information This webinar will give an overview of programmatic access to the UniProt database using Python and cover key aspects of protein entry searches data filtering batch downloads and give examples of further processing of downloaded target data Following a brief introduction to UniProt services where to find relevant documentation and help features the webinar will focus on worked examples These will include how to programmatically search and retrieve protein entries and sequences within the results we will then show how to align orthologous sequences and filter for features of interest The webinar will also cover programmatic examples of the UniProt ID mapping service batch downloads filtering and processing data... UniProt is a comprehensive, expert-led, publicly available database of protein sequence, function and variation information.This webinar will give an overview of programmatic access to the UniProt database using Python and cover key aspects of protein entry searches, data filtering, batch downloads and give examples of further processing of downloaded target data.Following a brief introduction to UniProt services, where to find relevant documentation and help features, the webinar will focus on worked examples. These will include how to programmatically search and retrieve protein entries and sequences, within the results we will then show how to align orthologous sequences and filter for features of interest. The webinar will also cover programmatic examples of the UniProt ID mapping service, batch downloads, filtering, and processing data.

4 November - 8 November 2024

Structural bioinformatics

Juanita Riveros

This course provides a guide to the commonly used methods and tools in structural bioinformatics to analyse and interpret experimentally determined and AI predicted macromolecular structure data Structural biology determining the three dimensional shapes of biomacromolecules and their complexes can tell us a lot about how these molecules function and the roles they play within a cell Data derived from structure determination experiments and Artificial Intelligence AI assisted structure prediction enables life science researchers to address a wide variety of questions This course explores bioinformatics data resources and tools for the investigation analysis and interpretation of both experimentally determined and predicted biomacromolecular structures It will focus on how best to analyse and interpret available structural data to gain useful information given specific research contexts The course content will also cover predicting function and exploring interactions with other macromolecules Successful participants may be sent materials prior to the course These might include pre recorded talks and required reading or online training that will be essential to fully engage with the course... This course provides  a guide to the commonly used methods and tools in structural bioinformatics to analyse and interpret experimentally determined and AI-predicted macromolecular structure data.Structural biology, determining the three-dimensional shapes of biomacromolecules and their complexes, can tell us a lot about how these molecules function and the roles they play within a cell. Data derived from structure determination experiments and Artificial Intelligence (AI)-assisted structure prediction enables life-science researchers to address a wide variety of questions.  This course explores bioinformatics data resources and tools for the investigation, analysis, and interpretation of both experimentally determined and predicted biomacromolecular structures. It will focus on how best to analyse and interpret available structural data to gain useful information...

4 November - 8 November 2024

The fundamentals of high-end cell sorting

Beata Ramasz, Diana Ordonez

OverviewSpeakersPreliminary programmePractical informationSponsorsMedia kit Overview Course overview This course includes a robust theoretical part on the fundamentals of cell sorting delivered by world leading experts and practical sessions on using standard cuvette sorters In addition the course program will include principles applications and hands on sessions on Image Cell Sorting ICS... OverviewSpeakersPreliminary programmePractical informationSponsorsMedia kit Overview Course overview This course includes a robust theoretical part on the fundamentals of cell sorting delivered by world-leading experts and practical sessions on using standard cuvette sorters. In addition, the course program will include principles, applications, and hands-on sessions on Image Cell Sorting (ICS), allowing attendees to get in touch with this exciting technology! Audience The course is intended for Ph.D. students and postdocs who are starting to use or already using cell sorting in their research projects. Applicants with previous active knowledge of basic principles of flow cytometry and regular use of flow cytometers in daily research will profit most from the course content. Modules/Resources The topics that will be covered include; instrument set-up and validation, correct operation to...

5 November - 8 November 2024

DNA replication: from basic biology to disease

Anja Groth, Thanos Halazonetis, Helle Ulrich

OverviewSpeakersProgrammePractical informationSponsorsAboutMedia Kit Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Symposium overview There has been tremendous progress in the past few years regarding our understanding of DNA replication in eukaryotes both yeast and mammals Many important questions in the field are poised to be answered... OverviewSpeakersProgrammePractical informationSponsorsAboutMedia Kit Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Symposium overview There has been tremendous progress in the past few years regarding our understanding of DNA replication in eukaryotes, both yeast and mammals. Many important questions in the field are poised to be answered within the next decade. These include understanding DNA replication at the biochemical and three-dimensional protein structure levels. In addition, studies using high throughput technologies at the cellular and organismal levels are poised to answer how accurate replication of the genome is ensured by controlling origin firing in space and time. Session topics Replisome structure Origin selection, licensing and firing Chromatin replication Replication stress and fork stability Replication in cancer...

6 November 2024

A guide to Job Dispatcher sequence analysis tools and programmatic access

The Job Dispatcher at EMBL EBI provides free access to a variety of bioinformatics tools and biological datasets via web and programmatic interfaces This webinar will provide a comprehensive guide on navigating various sequence analysis tools EMBOSS Clustal Omega NCBI BLAST etc and showcase the newest updates to the website It will also demonstrate how to access these tools programmatically... The Job Dispatcher at EMBL-EBI provides free access to a variety of bioinformatics tools and biological datasets via web and programmatic interfaces. This webinar will provide a comprehensive guide on navigating various sequence analysis tools (EMBOSS, Clustal Omega, NCBI BLAST+, etc.) and showcase the newest updates to the website. It will also demonstrate how to access these tools programmatically.

13 November 2024

MGnify Proteins: a new resource of 2.5 billion proteins for exploring metagenomics sequence space

MGnify is EMBL EBI s microbiome data resource which enables the analysis and exploration of metagenomic metatranscriptomic amplicon and assembly data This webinar will showcase the recently released MGnify Proteins website which provides information regarding the proteins identified through MGnify s analysis pipeline In MGnify Proteins the information about proteins are accompanied by metadata such as underlying biological domains and encountered environments The protein sequence data is further utilised in other MGnify resources such as MGnifams to generate protein families models and structures... MGnify is EMBL-EBI’s microbiome data resource which enables the analysis and exploration of metagenomic, metatranscriptomic, amplicon and assembly data. This webinar will showcase the recently released MGnify Proteins website which provides information regarding the proteins identified through MGnify’s analysis pipeline. In MGnify Proteins the information about proteins are accompanied by metadata such as underlying biological domains and encountered environments. The protein sequence data is further utilised in other MGnify resources such as MGnifams, to generate protein families, models and structures.

14 November - 15 November 2024

The next generation in infection biology

Maria Bernabeu, Jan Kosinski, Eva Kowalinski, John Lees, Lizette de Paula, Nassos Typas

Infectious diseases are among the most prevalent causes of human illness and death in the world Pathogens infect humans and all life forms on Earth being able to cross species barriers thereby adversely impacting human and planetary health Fundamental research in Infection Biology is urgently needed to find therapies for longstanding and emerging infectious diseases... OverviewOrganisers and speakersParticipating organisationsPreliminary programmePractical informationSponsorsMedia kit Overview After the success of the virtual 2022 edition, this conference will return in a virtual format. Conference overview Infectious diseases are among the most prevalent causes of human illness and death in the world. Pathogens infect humans and all life forms on Earth, being able to cross species barriers, thereby adversely impacting human and planetary health. Fundamental research in infection biology is urgently needed to find therapies for longstanding and emerging infectious diseases.   The EMBL Conference ‘The next generation in infection biology’ is a platform for late-stage postdoctoral scientists in the field of infection biology to present their work and connect with the leading European institutions in infection biology. The speakers...

17 November - 22 November 2024

Humanized mice: immunotherapy and regenerative medicine

Christian Münz, Estefanía Rodríguez, Jan Jacob Schuringa, Leonard Shultz, Brian Soper, Renata Stripecke

OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview Course overview Humanized mouse models became an integral part of basic and translational biomedical research for the understanding of human pathologies and for development of new therapies Human cells or tissues implanted in mice can reflect human hematopoiesis immunity oncology infections physiology and genetic... OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview Course overview Humanized mouse models became an integral part of basic and translational biomedical research for the understanding of human pathologies and for development of new therapies. Human cells or tissues implanted in mice can reflect human hematopoiesis, immunity, oncology, infections, physiology and genetic polymorphisms. The development of immunotherapeutic drugs, cell and tissue therapies rely on the preclinical testing to assess their potency and safety. “Big pharma” and biotech companies include humanized mice in the non-clinical development portfolio. Humanized mouse models have varied among laboratories regarding the use of new transgenic and knock-out strains, improved handling methods, innovative sources and manipulation techniques of the human graft material and novel technological platforms for...

17 November - 24 November 2024

Integrative structural biology: solving molecular puzzles

Arjen Jakobi, Jan Kosinski, Maya Topf

This practical course offers a hands on introduction to integrative structural biology Participants will delve into the fundamentals of various experimental structure determination techniques including X ray crystallography cryo EM small angle X ray scattering NMR and mass spectrometry through both lectures and practical exercises... OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview Course overview Integrative structural biology has become a key strategy for determining the structure of biological macromolecules and their complexes. This method entails characterising the 3D structure through an array of complementary techniques, subsequently combining the data to form a consensus model using computational methodologies. This practical course offers a hands-on introduction to integrative structural biology. Participants will delve into the fundamentals of various experimental structure determination techniques including X-ray crystallography, cryo-EM, small-angle X-ray scattering, NMR, and mass spectrometry, through both lectures and practical exercises. Experts in the field will guide participants on how to analyse and interpret experimental data, and construct structural models across...

18 November - 22 November 2024

Plant genomes: from data to discovery

Barbara Etzi

This course will take you through a selection of genomic tools and open resources to help you explore plant genomes and answer biological questions Covering a range of omics data including genomic proteomic and imaging data this course will show you where to find relevant data and how to use publicly available tools to connect across resources supporting plant genomic data driven knowledge discovery Throughout the course you will address essential questions such as How can genomic data inform crop breeding strategies Which genetic variations contribute to plant resilience in changing environments How can proteomics enhance agricultural productivity The course instructors will guide you on how to navigate the different resources efficiently You will be shown how to submit your sequence to a public archive explore gene related information and variants within specific genes You will investigate functional conservation and expression patterns within gene families explore protein functional information as well as plant derived metabolomics and lipidomics data and analyse gene expression data Virtual courseParticipants will learn via a mix of pre recorded lectures live presentations and trainer Q A sessions Practical experience will be developed through trainer led computational exercises Live sessions will be delivered using Zoom with additional support and asynchronous communication via Slack Computational practicals will run using online tools meaning participants will not require access to a powerful computer or install complex software on their own machines In the week before the course there will be a brief induction session Participants will need to be available between the hours of 09 00 17 00 GMT each day of the course Trainers will be available to assist answer questions and provide further explanations during these times... This course will take you through a selection of genomic tools and open resources to help you explore plant genomes and answer biological questions. Covering a range of omics data including genomic, proteomic, and imaging data, this course will show you where to find relevant data and how to use publicly available tools to connect across resources supporting plant genomic data-driven knowledge discovery. Throughout the course, you will address essential questions, such as: How can genomic data inform crop breeding strategies? Which genetic variations contribute to plant resilience in changing environments? How can proteomics enhance agricultural productivity? The course instructors will guide you on how to navigate the different resources efficiently. You will be shown how to submit your sequence to a public archive, explore gene-related information and variants...

18 November - 22 November 2024

Genome bioinformatics: from short- to long-read sequencing

Meredith Willmott

A guide to the technology analysis workflows tools and resources for next generation sequencing data analysis This course will provide insights and training into how biological knowledge can be derived from genomics experiments and explain different approaches in analysing such data The main focus will be on introducing sequence informatics re sequencing differences between short and long read sequencing and variant calling during the analysis of higher eukaryotes with an emphasis on human genetic research Throughout the week more advanced topics will introduce genome graphs pangenomics the creation of pipelines automation and the scaling up of analysis experiments Practical sessions will be run on datasets prepared by the trainers not on personal research data Participants will learn how to process these training datasets and to apply appropriate statistical methods in their analyses They will also learn the basics to create their own pipelines and use pipelines openly available... A guide to the technology, analysis workflows, tools, and resources for next-generation sequencing data analysis.This course will provide insights and training into how biological knowledge can be derived from genomics experiments and explain different approaches in analysing such data. The main focus will be on introducing sequence informatics, re-sequencing, differences between short- and long-read sequencing, and variant calling during the analysis of higher-eukaryotes, with an emphasis on human genetic research. Throughout the week, more advanced topics will introduce genome graphs, pangenomics, the creation of pipelines, automation, and the scaling-up of analysis experiments.Practical sessions will be run on datasets prepared by the trainers, not on personal research data. Participants will learn how to process these training datasets and to apply appropriate statistical...

19 November - 22 November 2024

Quantitative biology to molecular mechanisms

Lacramioara Bintu, Hartland Jackson, Arnaud Krebs, Tineke Lenstra, Mikhail Savitski

OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview Late onsite registration is still available Please reach out to events embl org to request it This conference will take place at EMBL Heidelberg with the option to attend virtually and is being organised by EMBL with generous support from the Bayer Foundation Conference overview Recent decades have witnessed a... OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview Late onsite registration is still available. Please reach out to events@embl.org to request it. This conference will take place at EMBL Heidelberg, with the option to attend virtually and is being organised by EMBL with generous support from the Bayer Foundation Conference overview Recent decades have witnessed a profound transformation in molecular biology research, fueled by revolutionary technologies that have greatly enhanced our ability to systematically and quantitatively measure biological molecules. The use of genomics, proteomics, and imaging have become routine, generating vast amounts of high-resolution data that characterise biological systems across multiple scales, ranging from molecules to organisms. This technological leap allows us to describe biological systems in quantitative terms with...

20 November 2024

Investigating gene function and human disease through data on the IMPC portal

The International Mouse Phenotyping Consortium IMPC is a resource created by an international collaborative effort from 21 research institutions aiming to identify the function of every mammalian protein coding gene using the mouse as a model organism Currently the IMPC has generated knockout lines for 8 901 mouse genes and studied them systematically to determine their function in different biological systems and their role in disease This webinar will offer an overview of how IMPC data is generated along with a guided tour of the website showcasing key features and available data We will also explore how phenotype data can be used to investigate Mendelian diseases and how the PhenoDigm algorithm can be applied to identify new models of human disease gene associations... The International Mouse Phenotyping Consortium (IMPC) is a resource created by an international collaborative effort from 21 research institutions, aiming to identify the function of every mammalian protein-coding gene using the mouse as a model organism. Currently, the IMPC has generated knockout lines for 8,901 mouse genes, and studied them systematically to determine their function in different biological systems and their role in disease.This webinar will offer an overview of how IMPC data is generated, along with a guided tour of the website, showcasing key features and available data. We will also explore how phenotype data can be used to investigate Mendelian diseases, and how the PhenoDigm algorithm can be applied to identify new models of human disease-gene associations.

28 November 2024

Small molecule chemistry: from proteins to pathways

Juanita Riveros

Small molecules play an important role in biological systems They provide the precursors to macromolecules have roles in cell signalling and regulation and can be used to treat diseases To understand the role of small molecules we can study their binding interactions with macromolecular targets such as nucleic acids and proteins and the functional impact on the target and biological pathways This six hour virtual workshop will provide participants with an opportunity to gain hands on experience of using EMBL EBI tools and resources to assess the impact of drugs on their protein target and place these interactions within the context of biological pathways During this course we ll explore the biological effects of small molecules using a therapeutic drug as an example We ll consider a workflow that investigates drug binding to a protein target and the downstream pathway effects EMBL EBI tools and resources will be used to identify small molecule drugs evaluate protein binding and investigate pathway effects... Small molecules play an important role in biological systems. They provide the precursors to macromolecules, have roles in cell signalling and regulation, and can be used to treat diseases. To understand the role of small molecules, we can study their binding interactions with macromolecular targets, such as nucleic acids and proteins, and the functional impact on the target and biological pathways. This six-hour virtual workshop will provide participants with an opportunity to gain hands-on experience of using EMBL-EBI tools and resources to assess the impact of drugs on their protein target and place these interactions within the context of biological pathways.During this course, we’ll explore the biological effects of small molecules using a therapeutic drug as an example. We’ll consider a workflow that investigates drug binding to a protein target and the downstream pathway effects....

3 December - 6 December 2024

Hands-on course for sample preparation and data analysis in proteomics

Mandy Rettel, Mikhail Savitski, Frank Stein

OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview Course overview The course will give an introduction to the theoretical aspects of the analysis of proteins peptides by mass spectrometry Participants will get hands on experience in sample preparation for a quantitative comparison across samples and perform a state of the art sample preparation and tandem mass tag... OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview Course overview The course will give an introduction to the theoretical aspects of the analysis of proteins/peptides by mass spectrometry. Participants will get hands-on experience in sample preparation for a quantitative comparison across samples and perform a state of the art sample preparation and tandem mass tag labelling. Samples prepared by the participants will be measured by liquid chromatography-tandem mass spectrometry. In a session focused on bioinformatics analysis, participants will use FragPipe and FragPipe-Analyst in order to process the acquired data. Audience The course is intended for scientists that use or want to use proteomics for their research. Applicants should have an understanding of protein biology and should know the principle of proteomics. Ideally, they have some prior experience with...

27 January - 31 January 2025

Computing skills for reproducible research: software carpentry

Renato Alves, Lisanna Paladin, Christian Schudoma

OverviewSpeakersPreliminary programmePractical informationSponsorsMedia kit Overview Course overview Computation is an integral part of today s research as data has grown too large or too complex to be analysed by hand An ever growing fraction of science is performed computationally but many scientists struggle with this aspect of research as they have not been properly trained in the... OverviewSpeakersPreliminary programmePractical informationSponsorsMedia kit Overview Course overview Computation is an integral part of today’s research as data has grown too large or too complex to be analysed by hand. An ever-growing fraction of science is performed computationally but many scientists struggle with this aspect of research as they have not been properly trained in the necessary set of skills. The result is that too much time is spent doing steps manually or using inefficient tools when progress could be faster. This course provides training in several key tools, with a focus on good development practices that encourage efficient and reproducible research computing. Audience This course is aimed at researchers in the life sciences who wish to use or design analysis pipelines on individual or clusters of computers. The target learner is familiar with some command...

4 February - 7 February 2025

In situ structural biology: expanding the toolbox for structural cell biology

Julia Mahamid, Jonas Ries, Stefano Vanni

This conference will bring together experts and early stage researchers from the separate fields to define what types of biological questions can already be addressed using in situ structural biology and which might be approached in the future... OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Conference overview There is an increasing awareness that mechanistic understanding of complex cellular functions and interactions requires structural knowledge of the macromolecules involved. Recent technological advances in several disciplines nurture the development of in situ structural biology approaches, that have separately started to provide structural information on molecules within the context of intact cells in order to fully grasp how they function in their native environment. These include cryo-electron microscopy and tomography (EM/ET), mass spectrometry-based proteomics, fluorescence and super-resolution light microscopy, protein structure prediction, multi-scale computational modelling and others. This conference...

9 February - 14 February 2025

In situ CLEM at room temperature and in cryo

Ori Avinoam, Mandy Bormel, Rachel Mellwig

During this course we will focus on a specific method that has been developed at EMBL that enables the localisation of fluorescent proteins with high accuracy at the ultrastructural level The course will cover both the theory and practicals of high precision CLEM as well as opportunities to discuss their research with CLEM experts and receive practical and troubleshooting advice... OverviewSpeakersPreliminary ProgrammePractical informationSponsorsMedia kit Overview Course overview The course is designed to equip participants with both practical, hands-on skills in Correlative Light and Electron Microscopy (CLEM) and a solid theoretical foundation. This advanced imaging modality enables researchers to precisely locate fluorescent proteins within cellular ultrastructures, a technique pioneered at the European Molecular Biology Laboratory (EMBL). Recognizing the increasing demand for in situ CLEM applications, the training is geared towards enabling attendees to create customized CLEM workflows to address their unique research questions and share this knowledge within their institutions. Our course delves into the specifics of this method, emphasising high-precision localization. Furthermore, it offers significant interaction with CLEM and EM experts, facilitating...

17 February - 21 February 2025

Single-cell RNA-seq analysis with Python

Juanita Riveros

This course covers the analysis of single cell RNA sequencing scRNA seq data using Python and command line tools Participants will be guided through droplet based scRNA seq analysis pipelines from raw reads to cell clusters You will explore and interpret single cell RNA seq data using Python as well as the Single Cell Expression Atlas Finally you will put their knowledge into practice through a group challenge on the last day Please note that you will not analyse your own data as part of the course There will however be ample opportunity to discuss your research and ideas with other course participants and trainers Virtual courseParticipants will learn via a mix of pre recorded lectures live presentations and trainer Q A sessions Practical experience will be developed through group activities and trainer led computational exercises Live sessions will be delivered using Zoom with additional support and asynchronous communication via Slack Pre recorded material may be provided before the course starts that participants will need to watch read or work through to gain the most out of the actual training event In the week before the course there will be a brief induction session Computational practicals will run on EMBL EBI s virtual training infrastructure meaning you will not require access to a powerful computer or install complex software on your own machines Participants will need to be available between the hours of 09 00 17 30 BST each day of the course Trainers will be available to assist answer questions and provide further explanations during these times Please note that we will operate this course virtually Hybrid options are not currently available We reserve the right to change the format of this course or cancel it... This course covers the analysis of single cell RNA sequencing (scRNA-seq) data using Python and command line tools. Participants will be guided through droplet-based scRNA-seq analysis pipelines from raw reads to cell clusters. You will explore and interpret single-cell RNA seq data using Python as well as the Single Cell Expression Atlas. Finally, you will put their knowledge into practice through a group challenge on the last day.Please note that you will not analyse your own data as part of the course. There will, however, be ample opportunity to discuss your research and ideas with other course participants and trainers.Virtual courseParticipants will learn via a mix of pre-recorded lectures, live presentations, and trainer Q&A sessions. Practical experience will be developed through group activities and trainer-led computational exercises. Live sessions will be delivered using...

17 February - 21 February 2025

Advanced deep learning for image analysis

Anna Kreshuk, Florian Jug, Constantin Pape, Martin Weigert

OverviewSpeakersPreliminary programmePractical informationSponsorsMedia kit Overview Course overview The advent of deep learning has brought a revolution in the field of computer vision including most tasks and research questions concerned with microscopy image analysis Neural networks have been successfully used for image restoration classification and segmentation for the detection of... OverviewSpeakersPreliminary programmePractical informationSponsorsMedia kit Overview Course overview The advent of deep learning has brought a revolution in the field of computer vision, including most tasks and research questions concerned with microscopy image analysis. Neural networks have been successfully used for image restoration, classification and segmentation, for the detection of objects and characterisation of their morphology, and for high-throughput imaging and large-scale processing in 3D. Despite these advances, training and deployment of such neural networks remains difficult for practitioners of image analysis. The aim of our course is to close this gap and teach the participants, in the most hands-on way possible, to apply deep learning-based methods to their own data and image analysis problems. This time, we aim not to start from scratch but to address participants...

23 February - 28 February 2025

Extracellular vesicles: from biology to biomedical applications

An Hendrix, Cecilia Lässer, Esther Nolte-T Hoen, Guillaume Van Niel

A rapidly increasing number of researchers aim to purify and identify extracellular vesicles and many methodologies to isolate and analyse these vesicles are available and have been implemented This course will cover the basics possibilities and limitations of different purification and characterisation techniques and will address strategies to understand their role in biomedical applications... OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview Course overview The extracellular vesicle (EV) research field is still growing with many researchers entering the field with a continued strength of demand for such specialized training. As research progresses, it becomes clear that EV’s regulate an increasing number of (Patho)physiological processes and are harnessed in a variety of biomedical applications. Appropriate methodologies to prepare and characterize EV from biofluids are key to understanding the mechanisms that regulate their formation, composition and function. Given the large number of methods used, it is particularly important to provide practical hands-on training to new researchers covering the possibilities and limitations of the most widely used methods. This course will deliver such state-of-the-art training to participants, particularly...

24 February - 28 February 2025

Introduction to RNA-seq and functional interpretation

Barbara Etzi

Gain an introduction to the technology data analysis tools and resources used in RNA sequencing and transcriptomics The content will provide a broad overview of the subject area and introduce participants to basic analysis of transcriptomics data using the command line It will also highlight key public data repositories and methodologies that can be used to start the biological interpretation of expression data Topics will be delivered using a mixture of lectures practical exercises and open discussions Computational work during the course will use small example data sets and there will be no opportunity to analyse personal data Please note that this course covers different topics related to bulk RNA Seq data analysis Other related techniques such as single cell and spatial transcriptomics will not be covered Nonetheless the overview lecture will describe the potentials and limitations of the most commonly used RNA Sequencing analysis techniques and the context in which they are used If you are seeking training on single cell please consider applying to the 2025 Single cell RNA seq analysis with Python virtual course which will run about the same dates Virtual courseParticipants will learn via a mix of pre recorded lectures live presentations and trainer Q A sessions Practical experience will be developed through group activities and trainer led computational exercises Live sessions will be delivered using Zoom with additional support and asynchronous communication via Slack Pre recorded material may be provided before the course starts that participants will need to watch read or work through to gain the most out of the actual training event In the week before the course there will be a brief induction session Computational practicals will run on EMBL EBI s virtual training infrastructure meaning participants will not require access to a powerful computer or install complex software on their own machines Participants will need to be available between the hours of 08 00 18 00 GMT each day of the course Trainers will be available to assist answer questions and provide further explanations during these times... Gain an introduction to the technology, data analysis, tools, and resources used in RNA sequencing and transcriptomics. The content will provide a broad overview of the subject area, and introduce participants to basic analysis of transcriptomics data using the command line. It will also highlight key public data repositories and methodologies that can be used to start the biological interpretation of expression data. Topics will be delivered using a mixture of lectures, practical exercises, and open discussions. Computational work during the course will use small, example data-sets; and there will be no opportunity to analyse personal data.Please note that this course covers different topics related to bulk RNA-Seq data analysis. Other related techniques such as single-cell and spatial transcriptomics will not be covered. Nonetheless, the overview lecture will describe the potentials...

3 March - 7 March 2025

Introduction to multi-omics data integration and visualisation

Meredith Willmott

With the increase in the volume of data across the whole spectrum of biology more opportunities as well as challenges have been created to identify novel perspectives and answer questions in life sciences This may also include public domain data which can provide added value to data derived through the researcher s own work and inform experimental design This introductory course will highlight the challenges that researchers face in integrating multi omics data sets using biological examples The course will focus on the use of public data resources and open access tools for enabling integrated working with an emphasis on data visualisation This course will not include systems biology modelling or machine learning A major element of this course is a group project where participants will be placed in small groups to work together on a challenge set by trainers from EMBL EBI data resource and research teams This allows participants to explore the bioinformatics tools and resources introduced in the course and to apply these to a set problem providing hands on experience of relevance to their own research The group work will culminate in a presentation session involving all participants on the final day of the course allowing wider discussion on the benefits and challenges of integrating data... With the increase in the volume of data across the whole spectrum of biology, more opportunities, as well as challenges, have been created to identify novel perspectives and answer questions in life sciences. This may also include public domain data, which can provide added value to data derived through the researcher’s own work and inform experimental design. This introductory course will highlight the challenges that researchers face in integrating multi-omics data sets using biological examples. The course will focus on the use of public data resources and open access tools for enabling integrated working, with an emphasis on data visualisation. This course will not include systems biology modelling or machine learning.A major element of this course is a group project, where participants will be placed in small groups to work together on a challenge set by trainers from EMBL-EBI...

9 March - 14 March 2025

Quantitative proteomics: strategies and tools to probe biology

Jeroen Krijgsveld, Christina Ludwig, Mikhail Savitski

OverviewSpeakersPreliminary programmePractical informationSponsorsMedia kit Overview Course overview Proteomic technologies continue to develop at a rapid pace offering the potential to address imminent questions in a range of biological research areas Mass spectrometry has become widely accessible to many biologists either through core facilities or scientific collaborations Becaus... OverviewSpeakersPreliminary programmePractical informationSponsorsMedia kit Overview Course overview Proteomic technologies continue to develop at a rapid pace, offering the potential to address imminent questions in a range of biological research areas. Mass spectrometry has become widely accessible to many biologists, either through core facilities or scientific collaborations. Because quantitative proteomics includes a variety of specialised technologies and workflows, each with specific advantages and limitations, this hands-on practical course aims to train biologists on how to best integrate these evolving proteomics technologies into their own research. To achieve this, expert tutors will offer hands-on training in the analysis, interpretation, and statistical evaluation of various types of proteomic data through teaching methodological concepts integrated with software-driven...

11 March - 14 March 2025

The expanding world of RBPs: from posttranscriptional control to riboregulation

Francesca Cuttruzola, Imed Gallouzi, Matthias Hentze, V. Narry Kim

OverviewSpeakersPreliminary programmePractical InformationSponsorsMedia kit Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Conference overview Based on recent methodological breakthroughs the number of identified mammalian RNA binding proteins RBPs has skyrocketed from around 700 to over 2000 More importantly completely new classes... OverviewSpeakersPreliminary programmePractical InformationSponsorsMedia kit Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Conference overview Based on recent methodological breakthroughs, the number of identified mammalian RNA-binding proteins (RBPs) has skyrocketed from around 700 to over 2000. More importantly, completely new classes of proteins (including enzymes, signaling molecules, transporters and channels etc.) were recognized as RBPs, posing questions regarding the biological functions of RNA binding. This meeting will bring together leaders in the field of RBPs – classical and newly discovered – and discuss exciting progress on all fronts, from posttranscriptional regulation of RNA expression to the riboregulation of protein functions, facilitated by rapidly emerging experimental technologies and data analysis tools....

17 March - 21 March 2025

Gene-environment interactions in human health and disease

Juanita Riveros

This introductory course explores the complex interplay between genes and the environment in shaping human phenotypes Participants will gain knowledge of cohort datasets environmental readouts and computational resources to investigate gene environment interactions Ethical and legal frameworks related to data privacy and consent will be discussed The course also covers computational modelling techniques for integrating genotype and environmental effects By the end attendees will be equipped to analyse cohort datasets make use of computational resources and interpret the results Please note that you will not analyse your own data as part of the course There will however be ample opportunity to discuss your research and ideas with other course participants and trainers... This introductory course explores the complex interplay between genes and the environment in shaping human phenotypes. Participants will gain knowledge of cohort datasets, environmental readouts, and computational resources to investigate gene-environment interactions. Ethical and legal frameworks related to data privacy and consent will be discussed. The course also covers computational modelling techniques for integrating genotype and environmental effects. By the end, attendees will be equipped to analyse cohort datasets, make use of computational resources, and interpret the results. Please note that you will not analyse your own data as part of the course. There will, however, be ample opportunity to discuss your research and ideas with other course participants and trainers

18 March - 21 March 2025

Mechanisms of drug resistance and tolerance in bacteria, fungi, and cancer

Judith Berman, Markus Ralser, Luiz Carvalho, Marina Rodnina

OverviewSpeakersAboutPreliminary ProgrammePractical informationSponsorsMedia kit Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Symposium overview Resilience to antimicrobial drugs is a rapidly increasing problem of global health Similarly cancer cells that become drug resistant or tolerant affect therapy outcomes for instance during... OverviewSpeakersAboutPreliminary ProgrammePractical informationSponsorsMedia kit Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Symposium overview Resilience to antimicrobial drugs is a rapidly increasing problem of global health. Similarly, cancer cells that become drug-resistant or tolerant affect therapy outcomes, for instance during cancer chemotherapy. The underlying biological mechanisms of tolerance, resistance, and persistence are increasingly being studied and reveal a complex interplay between (cellular) evolution, biochemistry, and metabolism. Understanding these mechanisms holds the long-term promise of developing new therapeutic strategies less prone to drug resistance and, in the short term, enhances our understanding of clonal evolution and single-cell biology. With this new symposium, we aim to gather a highly...

23 March - 28 March 2025

Measuring translational dynamics by ribosome profiling

Pasha Baranov, Jan Medenbach, Sebastian Leidel, Elisabeth Zielonka

Quantitative assessment of mRNA translation is critical to understanding gene expression in many biological settings In this practical course we will summarise the state of the art in the theoretical sessions combined with hands on experiments and computational analyses Participants will learn a robust protocol and how to adapt it to different experimental systems and also learn the key steps of computational quality control... OverviewSpeakers, trainers and staffPreliminary ProgrammePractical informationSponsorsMedia kit Overview Course overview Regulation of translation is key in the control of gene expression, playing a critical role in many biological and pathophysiological settings. In the last decade, methodological advances have provided comprehensive insights into cellular transcriptomes and proteomes, however, the systems-wide analysis of translation remained an unsolved experimental challenge. The advent of ‘ribosome-profiling’ provided the methodological basis for comprehensive transcriptome-wide analyses of translation at sub-codon resolution by the precise and high-throughput determination of ribosomal positions on mRNA. Its application in a variety of organisms yielded novel insights into protein synthesis and its dynamic regulation, significantly advancing our understanding of the...

31 March - 2 April 2025

AI in one health

Oliver Billker, Lionel Christiaen, Anna Kreshuk, Giancarlo Russo, Sameer Velankar, Qi Zhang

OverviewScientific OrganisersYoung Investigators MeetingPractical InformationSponsorsMedia kit Overview Registration is not yet open for this event If you are interested in receiving more information please register your interest Overview The 5th EMBL Partnership Conference will be held in Heidelberg from 31 March 02 April 2025 The conference brings together EMBL and its partner... OverviewScientific OrganisersYoung Investigators MeetingPractical InformationSponsorsMedia kit Overview Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Overview The 5th EMBL Partnership Conference will be held in Heidelberg from 31 March – 02 April 2025. The conference brings together EMBL and its partner institutes to enable the exchange of expertise and build new collaborations and research networks.  The programme will focus on the impact of the recent advances in artificial intelligence (AI) on topics related to Health and related life science areas across 3 different sessions. Session topics Molecular medicine and precision health Genetics and genomics Technology and imaging Scientific Organisers Oliver Billker The Laboratory for Molecular Infection Medicine Sweden (MIMS) Sweden Lionel Christiaen...

31 March - 4 April 2025

Microscopy data analysis: machine learning and the BioImage Archive

Meredith Willmott

This virtual course will show how public bioimaging data resources centred around the BioImage Archive enable and enhance machine learning based image analysis The content will explore a variety of data types including electron and light microscopy and miscellaneous or multi modal imaging data at the cell and tissue scale Participants will cover contemporary biological image analysis with an emphasis on machine learning methods as well as how to access and use images from databases Virtual courseThis course will be a virtual event delivered via a mixture of live streamed sessions pre recorded lectures and tutorials with live support We will be using Zoom to run the live sessions all fully password protected with automated English closed captioning and transcription with support and both scientific and social networking opportunities provided by Slack and other methods taking different time zones into account In order to make the most out of the course you should make sure to have a stable internet connection throughout the week and are available between 08 00 18 00 BST each day In the week before the course there will be a brief induction session Computational practicals will run on EMBL EBI s virtual training infrastructure meaning participants will not require access to a powerful computer or install complex software on their own machines Selected participants may be sent materials prior to the course These might include pre recorded talks and required reading or online training that will be essential to fully engage with the course... This virtual course will show how public bioimaging data resources, centred around the BioImage Archive, enable and enhance machine learning based image analysis. The content will explore a variety of data types including electron and light microscopy and miscellaneous or multi-modal imaging data at the cell and tissue scale. Participants will cover contemporary biological image analysis with an emphasis on machine learning methods, as well as how to access and use images from databases. Virtual courseThis course will be a virtual event delivered via a mixture of live-streamed sessions, pre-recorded lectures, and tutorials with live support. We will be using Zoom to run the live sessions (all fully password protected with automated English closed captioning and transcription) with support and both scientific and social networking opportunities provided by Slack and other methods,...

7 April - 14 April 2025

Microbial metagenomics: a 360º approach

Vladimir Benes, Giuseppe D´Auria, José Eduardo González-Pastor, Elisabeth Zielonka

OverviewSpeakers trainers and staffPreliminary programmePractical informationSponsorsMedia kit Overview Course overview This course will provide a global overview of the different metagenomic approaches to study microbial communities covering methods for the functional search of genes sequencing of metagenomes using the most recent technologies and in silico methods for sequence analysis... OverviewSpeakers, trainers, and staffPreliminary programmePractical informationSponsorsMedia kit Overview Course overview This course will provide a global overview of the different metagenomic approaches to study microbial communities, covering methods for the functional search of genes, sequencing of metagenomes using the most recent technologies and in silico methods for sequence analysis. During the course, participants will receive an overview of state-of-the-art genomic technologies and bioinformatic tools. A balanced approach of lectures and practical sessions will provide a general background and the latest advancements in the field as well as its relationship with other disciplines. The course will begin with experimental training in functional metagenomics by preparing metagenomic libraries for gene searching. Metagenomic DNA will be isolated from soil samples to analyze...

8 April - 11 April 2025

Wild frontiers of model organisms

Susana Coelho, Gautam Dey, Michael Dorrity, Nicole Dubilier, Flora Vincent

OverviewSpeakersPreliminary programmePractical informationSponsorsAboutMedia kit Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Symposium overview The scientific community relies on a small number of model organisms to study larger themes in biology with the assumption that gained insights can be extrapolated to most other organisms... OverviewSpeakersPreliminary programmePractical informationSponsorsAboutMedia kit Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Symposium overview The scientific community relies on a small number of model organisms to study larger themes in biology, with the assumption that gained insights can be extrapolated to most other organisms. However, recent advances in our ability to study organisms in the context of their natural environments have revealed that Jacques Monod’s famous quote, ‘What is true for E. coli is true for the elephant’ does not do justice to the vast diversity of life on our planet. We will highlight research that challenges classical model organisms by looking at fluctuating, natural environments as a rich, relevant inspiration for new experiments in the lab and explore the challenges associated with the establishment...

4 May - 9 May 2025

Analysis and integration of transcriptome and proteome data

Vladimir Benes, Raffaele Calogero, Daria Fijalkowska, Jeroen Krijgsveld, Lennard Martens

OverviewSponsorsMedia kit Overview Registration is not yet open for this event If you are interested in receiving more information please register your interest Course overview Systems biology is a still expanding field of research aiming to understand at the molecular level how cells tissues and organisms operate in their biological context Among the key technologies driving this... OverviewSponsorsMedia kit Overview Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Course overview Systems biology is a still expanding field of research aiming to understand at the molecular level how cells, tissues and organisms operate in their biological context. Among the key technologies driving this forward are next-generation sequencing and proteomics, as they provide powerful means to determine global expression levels of genes and proteins. Both fields have matured to a degree that they have now become accessible to researchers in many areas of biology. During this course, participants will gain theoretical insight in the structure of sequencing and proteomic data, and they will receive training in data analysis for the annotation, quantification, and statistical analysis of gene and protein...

6 May - 9 May 2025

Theory and concepts in biology

Alexander Aulehla, Christina Hueschen, Jordi Garcia-Ojalvo, Sriram Ramaswamy, Kirsty Wan

The goal of this symposium is to assemble an interdisciplinary community and to provide a platform to discuss perspectives on the role of theory in biology and importantly also vice versa the impact that biology can have on theory... OverviewSpeakersPreliminary ProgrammePractical informationSponsorsAboutMedia kit Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Symposium overview Recent progress in biology has led to an explosion of factual knowledge about the living world over a huge range of scales in space and time. Yet, many questions about how to make sense of this data remain across the entire diversity of the living world from the smallest bacterium to the ecosystems of the Serengeti. This meeting is the 2nd edition in a series of symposia aiming to bring together a diverse community of researchers interested in finding ways to transform into conceptual knowledge the ever-increasing amount of factual knowledge produced by biological research. The goal is to provide a platform to discuss perspectives on the role of theory in biology, and importantly also vice...

12 May - 16 May 2025

Cancer genomics and transcriptomics

EMBL-EBI Training

This course will focus on the analysis of data from genomic studies of cancer It will also highlight the application of transcriptomic analysis and single cell technologies in cancer Talks and interactive sessions will give an insight into the bioinformatic concepts required to analyse such data whilst practical sessions will enable the participants to apply statistical methods to the analysis of cancer genomics data under the guidance of the trainers Virtual courseParticipants will learn via a mix of pre recorded lectures live presentations and trainer Q A sessions Practical experience will be developed through group activities and trainer led computational exercises Live sessions will be delivered using Zoom with additional support and asynchronous communication via Slack Pre recorded material may be provided before the course starts that participants will need to watch read or work through to gain the most out of the actual training event In the week before the course there will be a brief induction session Computational practicals will run on EMBL EBI s virtual training infrastructure meaning participants will not require access to a powerful computer or install complex software on their own machines Participants will need to be available between the hours of 08 45 17 00 BST each day of the course Trainers will be available to assist answer questions and provide further explanations during these times... This course will focus on the analysis of data from genomic studies of cancer. It will also highlight the application of transcriptomic analysis and single-cell technologies in cancer. Talks and interactive sessions will give an insight into the bioinformatic concepts required to analyse such data, whilst practical sessions will enable the participants to apply statistical methods to the analysis of cancer genomics data under the guidance of the trainers.Virtual courseParticipants will learn via a mix of pre-recorded lectures, live presentations, and trainer Q&A sessions. Practical experience will be developed through group activities and trainer-led computational exercises. Live sessions will be delivered using Zoom with additional support and asynchronous communication via Slack.Pre-recorded material may be provided before the course starts that participants will need to watch,...

13 May - 16 May 2025

Chromatin and epigenetics

Asifa Akhtar, Amanda Fisher, Dirk Schubeler, Bing Ren

Epigenetics refers to heritable changes in gene expression that do not involve changes to the underlying DNA sequence At least three systems including DNA methylation histone modifications and non coding RNAs ncRNA are considered to play fundamental roles in epigenetic regulation Research over the last two decades has uncovered the role of epigenetics in a variety of human disorders and fatal diseases Moreover influence of age environment lifestyle and disease state on epigenetic states is being increasingly appreciated and actively studied This conference provides an international forum for cutting edge research in chromatin and epigenetics It provides the focal hub for people to present their research and exchange ideas in a virtual format Renowned speakers will cover the latest advances in the field... OverviewSpeakersPractical informationSponsorsMedia kit Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Conference overview Epigenetics refers to heritable changes in gene expression that do not involve changes to the underlying DNA sequence. At least three systems, including DNA methylation, histone modifications, and non-coding RNAs (ncRNA), are considered to play fundamental roles in epigenetic regulation. Research over the last two decades has uncovered the role of epigenetics in a variety of human disorders and fatal diseases. Moreover, influence of age, environment, lifestyle, and disease state on epigenetic states is being increasingly appreciated and actively studied. This conference provides an international forum for cutting-edge research in chromatin and epigenetics. It provides the ‘focal hub’ for scientists to...

18 May - 23 May 2025

Advanced fluorescence imaging techniques

Manuel Gunkel, Aliaksandr Halavatyi, Joana Delgado Martins, Stefan Marawske

This practical course will cover advanced light microscopy techniques and participants will learn how to derive qualitative and quantitative insights on molecular mechanisms in cells and developing organisms Invited guest researchers together with experts from the EMBL and microscopy professionals will foster an intense information flow with a balance of lectures and practical workshops The focus of the course will be on the use of fluorescence microscopy to obtain information about protein localisation dynamics and functions at different spatial scales... OverviewSponsorsMedia kit Overview Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Course overview This practical course will cover advanced light microscopy techniques and participants will learn how to derive qualitative and quantitative insights on molecular mechanisms in cells and developing organisms. Invited guest researchers together with microscopy experts from EMBL will foster an intense information flow with a balance of lectures and practical workshops. The focus of the course will be on the use of fluorescence microscopy to obtain information about localisation and functions of proteins and other bio-molecules at different spatial scales. Audience This course is directed towards researchers in the life sciences with access to light microscopy equipment, who have an immediate need to apply the...

20 May - 22 May 2025

BioMalPar XXI: biology and pathology of the malaria parasite

Yaw Aniweh, Liliana Mancio-Silva, Wiebke Nahrendorf, Stuart Ralph

OverviewSpeakersPreliminary ProgrammePractical InformationSponsors Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Registration is not yet open for this event If you are interested in receiving more information please register your interest Conference overview Malaria remains a significant global public health challenge with... OverviewSpeakersPreliminary ProgrammePractical InformationSponsors Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Conference overview Malaria remains a significant global public health challenge, with increasing drug resistance, COVID interruptions to interventions, and rising malaria deaths confounding our efforts against this persistent disease. BioMalPar reaffirms our commitment to understanding the Plasmodium parasite and its interactions with hosts and vectors. Despite the challenges, there are promising developments: new drug combinations are showing efficacy, and we now have two approved vaccines that offer hope for the future. Meeting for the 21st time, BioMalPar 2025 focusses on strengthening our global...

20 May - 23 May 2025

Introduction to metabolomics analysis

Juanita Riveros

This course will provide an introduction to metabolomics through lectures and hands on sessions using publicly available data software and tools Participants will become familiar with standardised workflows as well as with the current state of experimental design data acquisition LC MS MS imaging processing and modelling In addition they will learn about community standards and sharing in metabolomics particularly through the use of EMBL EBI s MetaboLights repository and Galaxy infrastructure Participants will learn through hands on tutorials to use tools available for data analysis and data submission Additionally case studies will be discussed to show how to employ the week s learning... This course will provide an introduction to metabolomics through lectures and hands-on sessions, using publicly available data, software, and tools. Participants will become familiar with standardised workflows as well as with the current state of experimental design, data acquisition (LC-MS, MS imaging), processing, and modelling. In addition, they will learn about community standards and sharing in metabolomics, particularly through the use of EMBL-EBI’s MetaboLights repository and Galaxy infrastructure. Participants will learn through hands-on tutorials to use tools available for data analysis and data submission. Additionally, case studies will be discussed to show how to employ the week’s learning.

26 May - 28 May 2025

Infection: pathogens, hosts, and microbiomes

Maria Bernabeu, Pascale Cossart, Hiten Madhani, Kim Orth, Michael Way

OverviewSpeakersProgrammePractical informationSponsorsAboutMedia kit Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Symposium overview Infectious diseases are among the most prevalent causes of human illness and death in the world Epidemics pandemics have shaped human evolution and history and although for a while they were... OverviewSpeakersProgrammePractical informationSponsorsAboutMedia kit Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Symposium overview Infectious diseases are among the most prevalent causes of human illness and death in the world. Epidemics & pandemics have shaped human evolution and history, and although for a while they were considered a solved problem for the developed world, the recent past has showed us all why this is not the case. Antimicrobial resistance, global warming, human population size increase, modern lifestyles (urbanization, traveling), decrease of wild-life habitats for pathogen reservoirs all contribute to creating an ideal setting for infectious diseases becoming an even greater challenge in the future. This symposium will bring together experts working on different pathogens (viruses, bacteria, fungi, and...

1 June - 6 June 2025

Whole transcriptome data analysis

Marco Beccuti, Vladimir Benes, Raffaele Calogero, Francesca Cordero

This course will teach the biological researchers how to analyse biological data sets using open source software Most of the analysis will be performed with docker4seq and rCASC packages which was developed to facilitate the use of computing demanding applications in the field of NGS data analysis... OverviewSponsorsMedia kit Overview Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Course overview This course will teach the biological researchers how to analyse biological data sets using open-source software. Most of the analysis will be performed with docker4seq and rCASC packages, which was developed to facilitate the use of computing demanding applications in the field of NGS data analysis. Docker4seq and rCASC packages use docker containers that embed demanding computing tasks (e.g. short reads mapping) into isolated containers. This approach provides multiple advantages: the user does not need to install all the software on its local server, the results generated by different containers can be organised in pipelines and reproducible research is guarantee by the possibility of sharing the docker...

3 June - 6 June 2025

25th international meeting of the European Light Microscopy Initiative

Elisa D’Este, Ulrike Engel, Elisa May, Rainer Pepperkok, Stefan Terjung, Timo Job Kristian Zimmermann

The primary goals of this conference are to advocate for light microscopy as an essential research tool in the life sciences and to enhance communication among researchers core facilities and the industry... OverviewPreliminary programmeIndustry workshopsExhibitionSponsorship Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Conference overview Founded in 2001, the European Light Microscopy Initiative (ELMI) was established to create a pivotal communication network among European scientists involved in light microscopy and equipment manufacturers. Its primary goals are to advocate for light microscopy as an essential research tool in the life sciences and to enhance communication among researchers, core facilities, and the industry. The 2025 edition of the European Light Microscopy Initiative 2025 Conference sees a return to the European Molecular Biology Laboratory (EMBL) in Heidelberg, for the first time since 2010....

10 June - 13 June 2025

The ageing genome: from mechanisms to disease

George Garinis, Jaqueline Jacobs, Björn Schumacher, Agnel Sfeir

OverviewSpeakersPreliminary ProgrammePractical InformationSponsorsAboutMedia kit Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Symposium overview Ageing is often considered a complex phenotype that affects multiple organs and tissues in a time dependent manner This may result in the aged population consuming a myriad of medications... OverviewSpeakersPreliminary ProgrammePractical InformationSponsorsAboutMedia kit Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Symposium overview Ageing is often considered a complex phenotype that affects multiple organs and tissues in a time-dependent manner. This may result in the aged population consuming a myriad of medications, each aimed to treat, but not cure, the affected tissue. Recent studies have demonstrated that the “Primary Hallmarks of Ageing” are a set of five molecular mechanisms that malfunction, independent of tissue type, and drive ageing. Hence, focusing on these five hallmarks simplifies the efforts to understand ageing-associated disease. This, the second edition of this symposium will bring together an all-new, international line-up of speakers to continue the exchange on the basic/mechanistic aspects of...

14 June - 20 June 2025

Computational modelling of multicellular systems

Katie Bentley, James Sharpe, Alejandro Torres-Sanchez

This practical course teaches the basics of multicellular modelling to any researcher wishing to enter the field particularly experimentalists with no prior experience of computational modelling... OverviewSpeakersSponsorsMedia kit Overview Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Course overview This practical course teaches the basics of multicellular modelling to any researcher wishing to enter the field, particularly experimentalists with no prior experience of computational modelling. It is a “hands-on” course with 60% of the time devoted to students working on laptops performing exercises designed to give a practical familiarity with different types of computational modelling. The course focuses on the dynamics of multicellular systems- from embryos to organoids, covering both the molecular side (how gene regulatory networks perform pattern formation) and also the mechanical side in 2D and 3D (how the movements and activities of many cells together leads to tissue-level morphogenesis and...

15 June - 20 June 2025

Imaging-based spatial-omics

Alvaro Crevenna, Andrea Radtke, Emerald Perlas, Sinem Saka,

OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview Registration is not yet open for this event If you are interested in receiving more information please register your interest Course overview Spatial biology is a rapidly evolving scientific topic with frequent and novel technological advances that have powerful application potential in the context of basic and... OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Course overview Spatial biology is a rapidly evolving scientific topic with frequent and novel technological advances that have powerful application potential in the context of basic and translational research. The aim of the course is to provide participants a comprehensive conceptual introduction and intensive hands-on practical training on the main techniques of Imaging-based spatial-omics, i.e. multiplex immunofluorescence and spatial transcriptomics. We will provide a general overview of the field through lectures from scientific experts, assist the participants on how to choose and implement the right method for their scientific needs, and finally also share practical tips and...

16 June - 17 June 2025

In science we trust?

Lucia von Bredow

This conference will analyse the importance of public trust in science in a post truth society from public involvement in science to implications on funding and resource allocation and the political consequences of losing societal trust and buy in Above all it will ask what we role we can all play in shaping the future path of increased societal trust in science... OverviewSpeakersPreliminary programmeSponsors Overview This conference will take place as in-person meeting onsite at EMBL Heidelberg. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Conference overview We live in an era characterised by dazzling scientific and technological progress on an unprecedented scale. From the application of new gene editing techniques, pioneering stem cell research, or rapid vaccine development to emerging technologies such as AI or organoid research, advances in life sciences offer a myriad of potential benefits to society. However, these scientific endeavours exist against a backdrop of misinformation and disinformation in the scientific arena, which have the potential to cast a shadow on the public perception of science. From attitudes surrounding scientific issues in the...

16 June - 21 June 2025

Data science for life scientists

EMBL-EBI Training

This course will introduce life scientists to practical data science topics such as data visualisation image analysis application of AI and use of publicly available databases This course is currently under development please check back again soon for further details... This course will introduce life scientists to practical data science topics such as data visualisation, image analysis, application of AI, and use of publicly available databases. This course is currently under development, please check back again soon for further details.

16 June - 20 June 2025

Summer school in bioinformatics

EMBL-EBI Training

This course provides an introduction to the use of bioinformatics in biological research giving you guidance for using bioinformatics in your work whilst also providing hands on training in tools and resources appropriate to your research You will initially be introduced to bioinformatics theory and practice including best practices for undertaking bioinformatics analysis data management and reproducibility You will be required to review some pre recorded material for their group project prior to the start of the course Group projectsA major element of this course is a group project where you ll be placed in small groups to work together on a challenge set by trainers from EMBL EBI and external institutes This allows you to explore the bioinformatics tools and resources available in your area of interest and apply them to a set problem providing you with hands on experience relevant to your own research The group work will culminate in a presentation session involving everyone on the final day of the course giving an opportunity for wider discussion on the benefits and challenges of working with biological data Groups are mentored and supported by the trainers who set the initial challenge but the groups will be responsible for driving their projects forward with all members expected to take an active role Groups are pre organised before the course and all group members will be sent some short homework in preparation for your project work prior to the start of the course Basic outlines of the projects on offer this year are given below In your application you must indicate your first and second choice of project based on which you think would benefit your research most Not all projects may be offered and final decisions on which projects will be run during the course will be made based on the number of applicants per project Most of the projects cover mammalian data sets however in many cases the methods and approaches taught are transferable to data from various species The projects are currently under development... This course provides an introduction to the use of bioinformatics in biological research, giving you guidance for using bioinformatics in your work whilst also providing hands-on training in tools and resources appropriate to your research.You will initially be introduced to bioinformatics theory and practice, including best practices for undertaking bioinformatics analysis, data management, and reproducibility. You will be required to review some pre-recorded material for their group project prior to the start of the course.Group projectsA major element of this course is a group project, where you'll be placed in small groups to work together on a challenge set by trainers from EMBL-EBI and external institutes. This allows you to explore the bioinformatics tools and resources available in your area of interest and apply them to a set problem, providing you with hands-on experience...

24 June - 27 June 2025

New approaches and concepts in microbiology

Pascale Cossart, Sophie Helaine, KC Huang, Michael Laub, Nassos Typas

This symposium will cover a broad range of topics in microbiology including antibiotic related research bacterial communities and microbiome cell biology regulation signalling pathogenesis and evolution Emphasis will be placed on novel approaches and technologies from systems based to single cell that drive each field or have the potential to revolutionise future research in microbiology... OverviewSpeakersPreliminary programmePractical informationSponsorsMedia kitAbout Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Symposium overview This symposium is the seventh edition of a successful series started in 2013 and held biannually since. It has established itself as a must-attend fixture in the calendar for scientists working with bacteria and new technologies. The meeting covers a broad range of cutting-edge topics in microbiology, featuring diverse research. Emphasis is placed on novel approaches and technologies (from systems-based to single-cell) that drive each field or have the potential to revolutionise future microbiology research. The meeting is always oversubscribed and manages to bring together scientists from different areas, who usually don’t meet, creating a highly interactive and dynamic atmosphere. Session...

24 June - 26 June 2025

Data visualisation for biology

EMBL-EBI Training

This course will give insights into and practical experience in data visualisation for exploring complex and multi dimensional biological data Biological and life sciences data often consists of multiple dimensions a combination of numerical values ordered data categories and time series To make sense of this data simple plots like scatterplots barcharts and boxplots are often not enough Still visualisation is critical in gaining deep insight into the data This is why many custom visualisations originated in the biological field In this course we will dive into the topic of visualisation of complex biological data and how it can be used to gain insight into and get a feel for a dataset so that targeted analyses can be defined It will be delivered through a mixture of lectures and workshop sessions and will provide hands on experience in developing visualisations The course will focus on working with omics e g genomics transcriptomics data rather than e g imaging data... This course will give insights into, and practical experience in, data visualisation for exploring complex and multi-dimensional biological data.Biological and life sciences data often consists of multiple dimensions: a combination of numerical values, ordered data, categories, and time-series. To make sense of this data, simple plots like scatterplots, barcharts, and boxplots are often not enough. Still, visualisation is critical in gaining deep insight into the data. This is why many custom visualisations originated in the biological field.In this course, we will dive into the topic of visualisation of complex biological data and how it can be used to gain insight into and get a "feel" for a dataset, so that targeted analyses can be defined. It will be delivered through a mixture of lectures and workshop sessions, and will provide hands-on experience in developing visualisations. The...

7 July - 11 July 2025

Systems biology: from large datasets to biological insight

EMBL-EBI Training

This course covers the use of computational tools to extract biological insight from omics datasets The content will explore a range of approaches ranging from network inference and data integration to machine learning and logic modelling that can be used to extract biological insights from varied data types Together these techniques will provide participants with a useful toolkit for designing new strategies to extract relevant information and understanding from large scale biological data The motivation for running this course is a result of advances in computer science and high performance computing that have led to groundbreaking developments in systems biology model inference With the comparable increase of publicly available large scale biological data the challenge now lies in interpreting them in a biologically valuable manner Likewise machine learning approaches are making a significant impact in our analysis of large omics datasets and the extraction of useful biological knowledge... This course covers the use of computational tools to extract biological insight from omics datasets. The content will explore a range of approaches – ranging from network inference and data integration to machine learning and logic modelling – that can be used to extract biological insights from varied data types. Together these techniques will provide participants with a useful toolkit for designing new strategies to extract relevant information and understanding from large-scale biological data.The motivation for running this course is a result of advances in computer science and high-performance computing that have led to groundbreaking developments in systems biology model inference. With the comparable increase of publicly-available, large-scale biological data, the challenge now lies in interpreting them in a biologically valuable manner. Likewise, machine learning approaches are...

14 July - 18 July 2025

Proteomics bioinformatics

EMBL-EBI Training

This course provides hands on training in the basics of mass spectrometry MS and proteomics bioinformatics You will receive training on how to use search engines and post processing software quantitative approaches MS data repositories the use of public databases for protein analysis annotation of subsequent protein lists and incorporation of information from molecular interaction and pathway databases The practical elements of the course will take raw data from a proteomics experiment and analyse it You will be able to go from MS spectra to identifying and quantifying peptides and finally to obtaining lists of protein identifiers that can be analysed further using a wide range of resources The final aim is to provide you with the practical bioinformatics knowledge you need to go back to the lab and process your own data when collected This course is organised in association with the Vlaams Instituut voor Biotechnologie VIB the Flemish Institute for Biotechnology Pre recorded material may be provided before the course starts that you will need to watch read or work through to gain the most out of the actual training event... This course provides hands-on training in the basics of mass spectrometry (MS) and proteomics bioinformatics. You will receive training on how to use search engines and post-processing software, quantitative approaches, MS data repositories, the use of public databases for protein analysis, annotation of subsequent protein lists, and incorporation of information from molecular interaction and pathway databases.The practical elements of the course will take raw data from a proteomics experiment and analyse it. You will be able to go from MS spectra to identifying and quantifying peptides, and finally to obtaining lists of protein identifiers that can be analysed further using a wide range of resources. The final aim is to provide you with the practical bioinformatics knowledge you need to go back to the lab and process your own data when collected.This course is organised in association...

14 July - 18 July 2025

Fluorescence imaging beyond intensity

Luis Alvarez, Manuel Gunkel, Andrea Mülter

As fluorescence lifetime based readouts become more accessible this course aims to provide a broad understanding of how the lifetime based information can be leveraged to solve biological questions... OverviewSponsors Overview Registration is not yet open for this event. If you are interested in receiving more information please register your interest. This course is organised in cooperation with Leica Microsystems. Course overview As fluorescence lifetime-based readouts become more accessible, this course aims to provide a broad understanding of how the lifetime-based information can be leveraged to solve biological questions. This application-centred course will provide insights into how this additional dimension of fluorescence information can help unveil functional and mechanistic information. Audience This course is aimed at PhD students and postdocs with experience in fluorescence microscopy. It will enable them to better apply confocal fluorescence microscopy and in particular lifetime-based readouts to their cutting-edge research, disseminate their gained expertise to...

15 July - 18 July 2025

Gene regulation: one molecule at a time

Stirling Churchman, Arnaud Krebs, Mounia Lagha, Daniel Larson

OverviewSponsors Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Registration is not yet open for this event If you are interested in receiving more information please register your interest Conference overview In the last 20 years genomics has revolutionised our understanding of genome organisation and its regulation It led to near... OverviewSponsors Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Conference overview In the last 20 years, genomics has revolutionised our understanding of genome organisation and its regulation. It led to near complete annotation of the genome and the factors regulating expression of our genes. Yet, almost all of this knowledge arises from experiments that sample millions of regulatory events to create an average static picture that fails to capture the mechanistic steps and the dynamics that underlie these complex processes. The last decade has seen the independent emergence in the field of microscopy and genomics of technologies able to study gene regulatory processes at the resolution of individual DNA...

3 September - 7 September 2025

Protein synthesis and translational control

Alfredo Castello, Christopher Fraser, Fatima Gebauer, Christian Spahn

This conference focuses on the process of protein synthesis from the molecular and structural understanding of the translational machinery to its regulation its implications in cell and organismal biology and its alteration in disease... OverviewSpeakersSponsorsProgrammePractical information Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Conference overview Mechanisms that shape cellular proteomes are critical for life. This conference focuses on the process of protein synthesis, from the molecular and structural understanding of the translational machinery to its regulation, its implications in cell and organismal biology, and its alteration in disease. The regulation of mRNA translation is critical to maintaining cell homeostasis and mediates cellular responses to environmental, physiological, and pathological cues. Given the central importance of protein synthesis, it is unsurprising that dysregulation or defects in mRNA translation are...

9 September - 12 September 2025

Developmental metabolism: flows of energy, matter, and information

Alexander Aulehla, Heather Christofk, Heidi Lempradl, Jonathan Rodenfels

This meeting will create an intellectual space to exchange ideas across disciplines and help form a vibrant diverse community at the interphase between developmental biology molecular metabolism mathematics and physics... OverviewSponsors Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Conference overview The fundamental question of the role of metabolism in development has seen a revival in interest over recent years, creating the need for the first edition of this workshop in 2023. This second edition is set to reunite the community two years on, and to ensure the ongoing interactions that can propel progress in developmental metabolism. In this rapidly advancing field, metabolomic methods play a crucial role in unraveling complex processes. The workshop will again aim to bring together researchers from diverse backgrounds: developmental biology, genetics, epigenetics, ecology, physics and math, to provide the developmental...

14 September - 19 September 2025

Advanced methods in bioimage analysis

Ignacio Arganda-Carreras, Anna Klemm, Perrine Paul-Gilloteaux, Christian Tischer

OverviewTrainers speakers staffSponsorsMedia kit Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Registration is not yet open for this event If you are interested in receiving more information please register your interest Course overview Microscopy is a key methodology in life science research where the reliability of... OverviewTrainers, speakers, staffSponsorsMedia kit Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Course overview Microscopy is a key methodology in life science research, where the reliability of scientific findings based on data generated on microscopes rely on substantiated qualitative and quantitative image data analysis. Due to the complexity of the data, without expert guidance, it is very likely that image analysis algorithms may be applied incorrectly, possibly even producing erroneous results. Moreover, the diversity of imaging modalities, analysis algorithms and software solutions is growing so rapidly that even experts are overwhelmed.  This course aims to promote excellence in bioimage analysis,...

15 September - 19 September 2025

Methods for infectious disease modelling using genomics

Barbara Etzi

The course will introduce concepts methods and tools for carrying out infectious disease modelling as well as for developing models further by leveraging the power of genomics... The course will introduce concepts, methods, and tools for carrying out infectious disease modelling, as well as for developing models further by leveraging the power of genomics.

16 September - 19 September 2025

The human microbiome

Mani Arumugam, Ami Bhatt, Peer Bork, Nicola Segata

OverviewSponsorsAbout Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Registration is not yet open for this event If you are interested in receiving more information please register your interest Symposium overview Human microbiota the collection of microbes living in and on our body have a significant impact on human health and... OverviewSponsorsAbout Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Symposium overview Human microbiota – the collection of microbes living in and on our body – have a significant impact on human health and well-being. They have been associated with numerous diseases, yet we are still far from understanding their role in the context of lifestyle and genetics. Various initiatives are underway around the world to survey the human microbiota at several body sites, characterise them, understand their interactions with the human hosts, elucidate their role in diseases, and design possible therapeutic or dietary interventions. There is a new wave of studies mining the human microbiota for health-relevant bioactive...

29 September - 2 October 2025

NicE-RNA sequencing for multiomics on open chromatin and transcription

Vladimir Benes, Björn Textor

OverviewSponsorsMedia kit Overview Course overview This course will focus on the latest state of the art novel library preparation protocols We will start with experimental design focusing on hands on library preparation including best practices standards and potential pitfalls concluding with sequencing of libraries bioinformatic evaluation best practices Multiomic data in... OverviewSponsorsMedia kit Overview Course overview This course will focus on the latest state-of-the-art novel library preparation protocols. We will start with experimental design, focusing on hands-on library preparation (including best practices, standards, and potential pitfalls), concluding with sequencing of libraries, bioinformatic evaluation & best practices. Multiomic data in scientific projects have become more and more important. NicE-Seq is a novel method enabling detection of open chromatin in fixed low numbers of cells without any additional instrumentation. Combining open chromatin with transcriptome information is crucial for interpretation of cellular states. Therefore, the course participants will also prepare mRNA libraries from the same cell populations.  Participants will carry out a complete workflow, from isolation of DNA & RNA from fixed cells,...

6 October - 10 October 2025

Metagenomics bioinformatics at MGnify

EMBL-EBI Training

Learn about the tools processes and analysis approaches used by MGnify in the field of genome resolved metagenomics This course will cover the use of publicly available resources to manage share analyse and interpret metagenomics data focussing primarily on the assembly based approaches used in MGnify analysis The delivered content will involve participants learning via live lectures and presentations followed by live Q As with the trainers Practical experience will be developed in group activities and in computational exercises run using containerised tools on our training infrastructure This course is currently under development please check back again soon for further details... Learn about the tools, processes, and analysis approaches used by MGnify in the field of genome-resolved metagenomics. This course will cover the use of publicly available resources to manage, share, analyse, and interpret metagenomics data, focussing primarily on the assembly-based approaches used in MGnify analysis. The delivered content will involve participants learning via live lectures and presentations, followed by live Q&As with the trainers. Practical experience will be developed in group activities and in computational exercises run using containerised tools on our training infrastructure. This course is currently under development, please check back again soon for further details.

8 October - 11 October 2025

Seeing is believing: imaging the molecular processes of life

Jan Ellenberg, Jennifer Lippincott-Schwartz, Satyajit Mayor, Atsushi Miyawaki

OverviewSponsorsSpeakersProgrammePractical informationMedia kit Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Registration is not yet open for this event If you are interested in receiving more information please register your interest Conference overview The molecular processes of life are naturally dynamic in space and time from... OverviewSponsorsSpeakersProgrammePractical informationMedia kit Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Conference overview The molecular processes of life are naturally dynamic in space and time from the atomic to the organismal level. The rapid development of imaging methods across the full scale of biological organisation is revolutionising our ability to visualise the inner workings of macromolecular complexes, organelles, cells, tissues, organs and whole organisms. Being able to see biological processes unfold in real time allows us to understand the mechanisms of life as well as disease.The symposium will bring together the leading developers of imaging methods with cutting-edge applications that...

13 October - 17 October 2025

Liquid biopsies

Anders Ståhlberg, Martin Dalin

OverviewSponsors Overview Registration is not yet open for this event If you are interested in receiving more information please register your interest Course Overview There is an increasing interest and need to analyse biomarkers in liquid biopsies including basic research and clinical applications Liquid biopsies have several advantages including being minimally invasive allowing... OverviewSponsors Overview Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Course Overview There is an increasing interest and need to analyse biomarkers in liquid biopsies, including basic research and clinical applications. Liquid biopsies have several advantages including being minimally invasive, allowing repeated sampling and sampling is often clinical routine. This course will provide an overview of the several techniques to detect and analyse liquid biopsy-based analytes such as circulating tumour cells, cell-free tumor-DNA (ctDNA), miRNA, extracellular vesicles, mRNA, carbohydrates and proteins. Participants will be introduced to all aspects ranging from proper sampling through analyte analysis and final data analysis. Experimentally, we will demonstrate ultrasensitive ctDNA analysis using sequencing...

22 October - 25 October 2025

Organoids: modelling organ development and disease in 3D

Meritxell Huch, Karl R. Koehler, Madeline Lancaster, Esther Schnapp

The aim of this meeting is to bring together researchers from different fields to enhance our understanding of how organoids can be formed and maintained how they can be used to study disease and how we might eventually use them to regenerate and replace human organ tissue... OverviewSpeakersSponsorsAbout Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Symposium overview The ability to grow tissues from stem cells in 3D culture to generate so-called organoids has revolutionised the study of tissue biology, especially human biology. This exciting technology has great potential for drug discovery and regenerative medicine. Because organoids model a variety of tissues with remarkably high fidelity, they allow for new discoveries in human development, homeostasis, regeneration, and disease. This symposium will bring together the leading researchers in this field, representing the premier conference for this research community, and providing a much-anticipated program that demonstrates how...

27 October - 31 October 2025

Structural bioinformatics

EMBL-EBI Training

This course provides a guide to the commonly used methods and tools in structural bioinformatics to analyse and interpret experimentally determined and AI predicted macromolecular structure data Structural biology determining the three dimensional shapes of biomacromolecules and their complexes can tell us a lot about how these molecules function and the roles they play within a cell Data derived from structure determination experiments and Artificial Intelligence AI assisted structure prediction enables life science researchers to address a wide variety of questions This course explores bioinformatics data resources and tools for the investigation analysis and interpretation of both experimentally determined and predicted biomacromolecular structures It will focus on how best to analyse and interpret available structural data to gain useful information given specific research contexts The course content will also cover predicting function and exploring interactions with other macromolecules This course is currently under development please check back again soon for further details... This course provides a guide to the commonly used methods and tools in structural bioinformatics to analyse and interpret experimentally determined and AI-predicted macromolecular structure data. Structural biology, determining the three-dimensional shapes of biomacromolecules and their complexes, can tell us a lot about how these molecules function and the roles they play within a cell. Data derived from structure determination experiments and Artificial Intelligence (AI)-assisted structure prediction enables life-science researchers to address a wide variety of questions.   This course explores bioinformatics data resources and tools for the investigation, analysis, and interpretation of both experimentally determined and predicted biomacromolecular structures. It will focus on how best to analyse and interpret available structural data to gain useful information given...

28 October - 30 October 2025

The epitranscriptome

Michaela Frye, Tsutomiu Suzuki, Chengqi Yi

OverviewSpeakersSponsors Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Registration is not yet open for this event If you are interested in receiving more information please register your interest Conference Overview The regulation of the transcriptome is key to cellular processes that underpin cell biology development and tissue... OverviewSpeakersSponsors Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Conference Overview The regulation of the transcriptome is key to cellular processes that underpin cell biology, development, and tissue function. All classes of cellular RNA are subject to post-transcriptional modification, be it by direct chemical modification, editing, or non-templated nucleotide additions. Now, in its fourth edition, ‘The epitranscriptome’ meeting first held at EMBL in 2016 (and repeated in 2018, then in 2022 as a virtual conference) was the first RNA modification-dedicated meeting with a focus on mammalian systems. It is now established that biochemical modifications of nucleotides regulate RNA metabolism,...

4 November - 7 November 2025

The mobile genome: genetic and physiological impacts of transposable elements

Deborah Bourc'his, Josefa Gonzalez Perez, Joseph Peters, Julius Brennecke

OverviewSponsors Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Registration is not yet open for this event If you are interested in receiving more information please register your interest Event details to be confirmed pending EMBO funding application Conference overview Disparaged as selfish DNA for decades it s now clear... OverviewSponsors Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Event details to be confirmed, pending EMBO funding application. Conference overview Disparaged as “selfish DNA” for decades, it’s now clear that transposable elements (TEs) underlie the remarkably dynamic nature of bacterial, plant, and animal genomes. This conference builds on the highly successful 2021 and 2023 Mobile Genome EMBO workshops and has emerged as the major European venue in this ever-growing cross-disciplinary research field. The 2025 Mobile Genome conference will assemble recognized experts from diverse disciplines (e.g., genomics, epigenetics, structural biology, evolutionary biology, and developmental biology), as...

10 November - 14 November 2025

Hands-on flow cytometry: learning by doing!

Daniel Gimenes, Diana Ordonez, Steffen Schmitt

This course aims to provide a comprehensive understanding of the underlying principles of flow cytometry while also emphasising practical considerations related to the most frequently used assays... OverviewSponsors Overview Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Course overview Flow cytometry is a highly effective method for analysing individual cells that has become widely used in the fields of life sciences and medicine. By utilising flow cytometry, researchers can accurately identify and measure specific cell populations within complex mixtures, as well as assess cell cycle progression, proliferation status, and expression of fluorescent markers. Our course aims to provide a comprehensive understanding of the underlying principles of flow cytometry, while also emphasising practical considerations related to the most frequently used assays. Through a combination of theoretical instruction and hands-on training, students will gain the knowledge and skills necessary to effectively design,...

11 November - 14 November 2025

Cancer genomics

Kathleen Burns, Isidro Cortés Ciriano, Mariam Jamal-Hanjani, Young Seok Ju

OverviewSponsors Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Registration is not yet open for this event If you are interested in receiving more information please register your interest Conference overview This meeting will provide an opportunity to learn about and keep up to date with the rapidly progressing area of cancer... OverviewSponsors Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Conference overview This meeting will provide an opportunity to learn about and keep up to date with the rapidly progressing area of cancer genomics. We aim to bring together scientists from across several disciplines connected with cancer research, for a unique opportunity to interact and stimulate further integration of these efforts. What past participants say about the conference “The EMBL ‘Cancer genomics’ conference was an exceptional experience, perfectlysynthesizing scientific and technical innovation guided by leading scientists and researchers in the field. It provided a great opportunity to learn and network with...

17 November - 21 November 2025

Genome bioinformatics: from short- to long-read sequencing

EMBL-EBI Training

A guide to the technology analysis workflows tools and resources for next generation sequencing data analysis This course will provide insights and training into how biological knowledge can be derived from genomics experiments and explain different approaches in analysing such data The main focus will be on introducing sequence informatics re sequencing differences between short and long read sequencing and variant calling during the analysis of higher eukaryotes with an emphasis on human genetic research Throughout the week more advanced topics will introduce the creation of pipelines automation and the scaling up of analysis experiments Practical sessions will be run on datasets prepared by the trainers not on personal research data Participants will learn how to process these training datasets and to apply appropriate statistical methods in their analyses This course is currently under development please check back again soon for further details... A guide to the technology, analysis workflows, tools, and resources for next-generation sequencing data analysis. This course will provide insights and training into how biological knowledge can be derived from genomics experiments and explain different approaches in analysing such data. The main focus will be on introducing sequence informatics, re-sequencing, differences between short- and long-read sequencing, and variant calling during the analysis of higher-eukaryotes, with an emphasis on human genetic research. Throughout the week, more advanced topics will introduce the creation of pipelines, automation, and the scaling-up of analysis experiments. Practical sessions will be run on datasets prepared by the trainers, not on personal research data. Participants will learn how to process these training datasets and to apply appropriate statistical methods in their analyses....

18 November - 21 November 2025

Cell biology of the nucleus

Simone Koehler, Patrick Lusk, Thomas Quail, Sara Wickström

OverviewSpeakersPractical informationSponsors Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Registration is not yet open for this event If you are interested in receiving more information please register your interest Conference overview The nucleus lies at the literal and figurative heart of the cell as the one organelle that all... OverviewSpeakersPractical informationSponsors Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Conference overview The nucleus lies at the literal and figurative heart of the cell – as the one organelle that all eukaryotes share, it is over 2 billion years old and integrated with every aspect of cellular function, from mechanosensing and genome regulation to membrane trafficking and cell division. Although the role of the nucleus in organising, housing and protecting the genome frequently takes centre stage, much remains to be discovered about the cellular physiology of this unique organelle studied in its own right rather than just as a passive scaffold for chromatin. This meeting will bring together a group of...

25 November - 27 November 2025

Managing a bioinformatics core facility

EMBL-EBI Training

This knowledge exchange workshop is an opportunity for managers of bioinformatics core facilities to learn from EMBL EBI s service teams and from each other These facilities play an essential role in enabling research in the molecular life sciences The landscape is constantly evolving as new research tools emerge as experiments become increasingly data intensive and as their clients experimental researchers become more exposed to the power of data driven biology This course will allow participants to share experiences discuss challenges and solutions that they face and plan ways to cope with the ever changing demands raised by the molecular life science field It will include sessions to learn from bioinformatics service providers hear how others have tackled common problems and work together to design core services resource them and measure their impact This course is currently under development please check back again soon for further details... This knowledge exchange workshop is an opportunity for managers of bioinformatics core facilities to learn from EMBL-EBI’s service teams, and from each other. These facilities play an essential role in enabling research in the molecular life sciences. The landscape is constantly evolving as new research tools emerge, as experiments become increasingly data-intensive, and as their clients – experimental researchers – become more exposed to the power of data-driven biology. This course will allow participants to share experiences, discuss challenges and solutions that they face, and plan ways to cope with the ever-changing demands raised by the molecular life science field. It will include sessions to learn from bioinformatics service providers, hear how others have tackled common problems, and work together to design core services, resource them, and measure their impact. This course is...

2 December - 5 December 2025

Computational structural biology

Rommie Amaro, Charlotte Deane, Jan Kosinski, Christine Orengo, Sameer Velankar

This conference will update on the impact of AI based structure prediction provide a forum to present new methods and applications build a wider community by integrating the new scientists now massively joining the field and open a platform to discuss future directions and opportunities... OverviewSponsors Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Conference overview The rapid evolution of computational structural biology, driven by AI, continues to revolutionise our understanding of biomolecular structures, functions, and interactions. This follow-up to the 2023 first edition of the workshop responds to the field’s swift advancements and the pressing need for a forum that not only aligns with this progress but also foresees future shifts. The conference aims to advance computational structural biology, promote the adoption of innovative methodologies, and enhance interdisciplinary research and collaborations. Capturing the latest advancements in this vibrant field, this second edition...

7 December - 12 December 2025

Genome engineering: CRISPR/Cas in cells and mice

Silke Deckert, Neil Humphreys, Kristof Kersse, Birgit Koch, Elisabeth Zielonka

OverviewSponsorsMedia kit Overview Registration is not yet open for this event If you are interested in receiving more information please register your interest Course overview This course will provide training in genome editing and cell engineering in mammalian cells and mouse embryos using the highly efficient CRISPR Cas9 system Participants will learn design of CRISPR targets using... OverviewSponsorsMedia kit Overview Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Course overview This course will provide training in genome editing and cell engineering in mammalian cells and mouse embryos using the highly efficient CRISPR/Cas9 system. Participants will learn design of CRISPR targets using bioinformatics tools, generation of gene knock-outs/knock-ins, and target validation using the most current technologies. The course will be split into two groups (mammalian cells OR mice) based on participants’ expertise. Please note that all participants are expected to engage in all sessions. Participants should plan for approximately 1 hour extra per day for self paced learning modules. Audience This course is aimed at researchers who are familiar with basic molecular and cell biology...

24 February - 27 February 2026

Collectivity in living systems: emergence, function, and evolution

Tomás Alarcón, Bernat Corominas-Murtra, Jordi van Gestel, Nicoletta Petridou, Allyson Sgro

OverviewSponsorsAboutMedia kit Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Registration is not yet open for this event If you are interested in receiving more information please register your interest Symposium overview Many of life s most fascinating phenomena emerge from interactions among its building blocks The initiation of a... OverviewSponsorsAboutMedia kit Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Symposium overview Many of life’s most fascinating phenomena emerge from interactions among its building blocks. The initiation of a heartbeat, the formation of bird flocks or the appearance of several pathologies can be explained with surprising accuracy through simple and universal principles arising from the interactions of the microscopic constituents of the system. Understanding how collective behaviour propagates across levels in biological systems – from cells, tissues, organs, organisms to animal groups – becomes, in consequence, a key and pressing issue lying at the core of the understanding of living systems. This symposium...

27 April - 30 April 2026

Sex differences in health and disease

Brian Aguado, Kristina Haase, Edith Heard, Irene Miguel-Aliaga

OverviewSponsorsAboutMedia kit Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Registration is not yet open for this event If you are interested in receiving more information please register your interest Symposium overview Sex differences range from distinct dimorphisms in appearance and physiology to behaviour variations across males... OverviewSponsorsAboutMedia kit Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Symposium overview Sex differences range from distinct dimorphisms in appearance and physiology to behaviour variations across males and females of the same species. These differences are numerous and varied and are often driven by combinations of genetic, hormonal and environmental factors. These differences also appear in manifestations of infectious disease, ageing and age-related diseases (cancer, cardiovascular and neurodegenerative diseases). Response to treatments can also vary drastically between females and males. Despite these wide-spread differences between sexes observed across species, the underlying mechanisms are poorly...