23 May - 25 May 2022

BioMalPar XVIII: biology and pathology of the malaria parasite

R. Dzikowski, S. Reece, M. Mota, C. Moxon

<div class="vf-tabs"><ul class="vf-tabs__list" data-vf-js-tabs="true"><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-53de8397-0f08-449c-b4a4-0fdca47249f2" data-vf-js-location-nearest-activation-target="">Overview</a></li><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-speakers" data-vf-js-location-nearest-activation-target="">Speakers</a></li><li class="vf-tabs_ OverviewSpeakersProgrammePractical informationSponsors Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Proof of COVID-19 vaccination or recovery is required for on-site attendance. Please see EMBL’s COVID-19">https://www.embl.org/about/info/course-and-conference-office/?page_id=1… terms and conditions. Conference overview Malaria remains one of the most significant global public health challenges, with more than 200 million clinical cases worldwide each year. The lack of a vaccine that provides effective long-term protection and the continual emergence of drug-resistant malaria parasites emphasises the need for new control and prevention strategies. This need for innovation has become even more apparent with the disruption of global malaria control programs due to the COVID-19 pandemic and potential reversal of gains made over the...

24 May - 27 May 2022

Introduction to metabolomics analysis

Meredith Willmott

<p><span><span><span><span><span><span>This course will provide an introduction to metabolomics using publicly available data, software and tools. Participants will become familiar with the current state of experimental design, data acquisition (LC-MS, GC-MS, MS imaging), processing and modelling as well as community standards and sharing in metabolomics, particularly through using the EMBL-EBI’s MetaboLights repository and Galaxy infrastructure. This course will provide an introduction to metabolomics using publicly available data, software and tools. Participants will become familiar with the current state of experimental design, data acquisition (LC-MS, GC-MS, MS imaging), processing and modelling as well as community standards and sharing in metabolomics, particularly through using the EMBL-EBI’s MetaboLights repository and Galaxy infrastructure. There will be a practical component, where participants will learn through hands-on tutorials to use tools available for data analysis and data submission. The course will be completed with an interactive session which will build on the week’s learning to discuss how to employ a metabolomics workflow with a case study. In-person course We plan to deliver this course in an in-person manner onsite at our training suite at EMBL-EBI, Hinxton.  Please be aware that we are continually...

25 May 2022

Exploring sequence alignment tools with Job Dispatcher

Nandana Madhusoodanan

<p><span><span><span><span><span><span>The Job Dispatcher framework at the EBI provides free access to several sequence analysis tools.&nbsp;</span></span></span></span></span></span></p> The Job Dispatcher framework at the EBI provides free access to several sequence analysis tools.  This webinar will introduce a list of sequence alignment resources available in Job Dispatcher. This will include both pairwise and multiple sequence alignment tools and provide some useful tips for using the tools. In addition to accessing these tools via the web browser, this webinar will also demonstrate accessing them by using the API.

26 May - 27 May 2022

EMBL in Italy 2022: Emerging approaches in human health and infectious diseases

EMBL Alumni Relations

<div class="wp-block-group"><div class="wp-block-group__inner-container"></div></div> <p>If you are not redirected automatically, <a href="https://www.embl.org/about/info/alumni/blog/events/embl-in-italy-2022/"… click here to visit the event website </a></p> If you are not redirected automatically, please">https://www.embl.org/about/info/alumni/blog/events/embl-in-italy-2022/"… click here to visit the event website

28 May - 4 June 2022

Characterization of macromolecular complexes by integrative structural biology

<div class="vf-tabs"><ul class="vf-tabs__list" data-vf-js-tabs="true"><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-0ca76819-6802-4cdd-9510-363cc44515b0">Tab 1</a></li></ul><div class="vf-tabs-content" data-vf-js-tabs-content="true"> <section class="vf-tabs__section" id="vf-tabs__section-0ca76819-6802-4cdd-9510-363cc44515b0"><h2>Tab 1</h2></section> </div></div> Tab 1 Tab 1

29 May - 3 June 2022

Whole transcriptome data analysis

Marco Beccuti, Vladimir Benes, Raffaele Calogero, Francesca Cordero

<div class="vf-tabs"><ul class="vf-tabs__list" data-vf-js-tabs="true"><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-53de8397-0f08-449c-b4a4-0fdca47249f2" data-vf-js-location-nearest-activation-target="">Overview</a></li><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-organisers" data-vf-js-location-nearest-activation-target="">Organisers</a></li><li class="vf-t OverviewOrganisersProgrammePractical InformationSponsors Overview Proof of COVID-19 vaccination or recovery is required to attend this on-site course. Please see EMBL’s COVID-19">https://www.embl.org/about/info/course-and-conference-office/?page_id=1… safety policy for on-site events. Course Overview This course will teach the biological researchers how to analyse biological data sets using open-source software. Most of the analysis will be performed with docker4seq package, which was developed to facilitate the use of computing demanding applications in the field of NGS data analysis. Docker4seq package uses docker containers that embed demanding computing tasks (e.g. short reads mapping) into isolated containers. This approach provides multiple advantages: the user does not need to install all the software on its local server, the results generated by different...

30 May 2022

EMBL in the UK 2022: Translating discovery into impact

EMBL Alumni Relations

<div class="wp-block-group"><div class="wp-block-group__inner-container"></div></div> <p>If you are not redirected automatically, <a href="https://www.embl.org/about/info/alumni/blog/events/embl-in-the-uk-2022/… click here to visit the event website. </a></p> If you are not redirected automatically, please">https://www.embl.org/about/info/alumni/blog/events/embl-in-the-uk-2022/… click here to visit the event website.

31 May 2022

Enabling imaging across scales

<div class="vf-tabs"><ul class="vf-tabs__list" data-vf-js-tabs="true"><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-53de8397-0f08-449c-b4a4-0fdca47249f2" data-vf-js-location-nearest-activation-target="">Overview</a></li><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-speakers" data-vf-js-location-nearest-activation-target="">Speakers</a></li><li class="vf-tabs_ OverviewSpeakersProgrammePractical InformationSponsors Overview This conference will take place at EMBL Heidelberg. Proof of COVID-19 vaccination or recovery is required for on-site attendance. Please see EMBL’s COVID-19">https://www.embl.org/about/info/course-and-conference-office/?page_id=1… safety policy for on-site events. Conference Overview The rapid developments of imaging technologies in the last two decades have led the scientific community to achieve biological and medical discoveries at an ever-increasing pace. Today, outstanding advances in electron (EM) and light microscopy (LM) enable us to directly visualise the molecular machinery of life at an unprecedented level of detail. To make the most advanced technologies available to the broad research community, EMBL has established a new service facility at the Heidelberg campus, the EMBL Imaging Centre. A synergistic...

1 June 2022

Computer-assisted functional precision medicine in cancer

Åsmund Flobak

<p>Biological mechanisms provide a link between anti cancer compounds and therapy responses. Insight to biological mechanisms is central for tomorrow’s clinical decision support systems and personalised cancer therapy. I will present the NTNU DrugLogics software that combines cancer signalling prior knowledge and data measurements to provide models that can predict therapy responses. Biological mechanisms provide a link between anti cancer compounds and therapy responses. Insight to biological mechanisms is central for tomorrow’s clinical decision support systems and personalised cancer therapy. I will present the NTNU DrugLogics software that combines cancer signalling prior knowledge and data measurements to provide models that can predict therapy responses. We combine in silico-generated predictions with in vitro observations in the PRESORT project where patient-derived cancer cultures are subjected to drugs and drug combinations predicted for the given patient, to appreciate the efficacy for individual patients. Together with Institut Curie, Charité, BSC, Uppsala University and ProtAtOnce, we test integrated computational and experimental pipelines on historic cohorts of patients treated at the molecular tumour boards at Institut Curie and Charité. Current...

8 June - 10 June 2022

Bioinformatics for principal investigators

Juanita Riveros

<p><span><span><span><span><span><span>This course has been designed to provide Principal Investigators (PI's) working in the life sciences with an introduction to the challenges of working with biological data as a research leader.</span></span></span></span></span></span></p> This course has been designed to provide Principal Investigators (PI's) working in the life sciences with an introduction to the challenges of working with biological data as a research leader. Starting with a look at where bioinformatics and data science fits into their research teams, the course will enable PI’s to take a strategic look at the requirements for undertaking such work and how bioinformatics capacity can be developed from personnel through to computational needs.  It will additionally provide guidance on strategies for managing data, and the importance of data sharing; how to work with computational collaborators and what resources are available across the life sciences to support such work. During this course we will not be teaching hands-on bioinformatics analysis, but we will be signposting appropriate training resources to upskill you and your team. This course is...

8 June - 11 June 2022

Microtubules: from atoms to complex systems

Anna Akhmanova, Carsten Janke, Kassandra Ori-McKenney, Manuel Théry

<div class="vf-tabs"><ul class="vf-tabs__list" data-vf-js-tabs="true"><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-53de8397-0f08-449c-b4a4-0fdca47249f2" data-vf-js-location-nearest-activation-target="">Overview</a></li><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-speakers" data-vf-js-location-nearest-activation-target="">Speakers and Organisers</a></li><li class OverviewSpeakers and OrganisersProgrammePractical InformationSponsorsAbout Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Proof of COVID-19 vaccination or recovery is required for on-site attendance. Please see EMBL’s COVID-19">https://www.embl.org/about/info/course-and-conference-office/?page_id=1… terms and conditions. Symposium Overview The microtubule cytoskeleton is essential for a wide variety of cellular functions, such as chromosome segregation, directed vesicle and organelle transport, cell motility and cell polarity. Impaired microtubule function can lead to human diseases including cancer and neurodegenerative disorders, where microtubules serve as important therapeutic targets. In recent years, interdisciplinary approaches embracing cell biology, genetics, molecular biology, biochemistry, biophysics, structural biology...

8 June 2022

Open-access to genetic variation data at the European Variation Archive

Baron Koylass

<p><span><span><span><span><span>The European Variation Archive (EVA) is an open-access database for archival and accessioning of genetic variants from any species. RS ID's are assigned to variants submitted to the EVA and this data is made available periodically. </span></span></span></span></span></p> The European Variation Archive (EVA) is an open-access database for archival and accessioning of genetic variants from any species. RS ID's are assigned to variants submitted to the EVA and this data is made available periodically. This webinar will cover various methods of data access, including bulk download of accessioned variants and a detailed dive into the latest EVA data release 3. This is the first release to contain existing variants updated to a new genome build.

9 June 2022

The PerMedCoE competency framework to guide training and career development

Vera Matser, Marta Lloret Llinares

<p>PerMedCoE aims at providing an efficient and sustainable infrastructure to support personalised medicine, adapting cell-level simulation methods to pre-exascale systems to translate omics data into molecular disease models. One of the activities to achieve this consists of a training programme to educate professionals in life sciences and HPC communities about the capabilities of PerMedCoE developments.</p> PerMedCoE aims at providing an efficient and sustainable infrastructure to support personalised medicine, adapting cell-level simulation methods to pre-exascale systems to translate omics data into molecular disease models. One of the activities to achieve this consists of a training programme to educate professionals in life sciences and HPC communities about the capabilities of PerMedCoE developments. We created a competency framework to define the training needs and, based on them, implement our training programme. A competency is an observable ability of any professional, integrating multiple components such as knowledge, skills and behaviours. The PerMedCoE framework lists the competencies for professionals within the scope of the CoE: developing cell-level simulation tools with the long-term vision of using them in the clinical context. The competency framework enables the...

12 June - 17 June 2022

BioExcel Summer School on Biomolecular Simulations 2022

Jane Reynolds

<p>The summer school will include lectures and hands-on sessions on the following topics:</p> <ul> <li>Molecular dynamics simulations</li> <li>Biomolecular docking</li> <li>Free energy calculations</li> <li>Advanced sampling methods (Metadynamics)</li> <li>BioExcel Building Blocks (BioBB)</li> <li>Quantum mechanics/molecular mechanics (QM/MM)</li> <li>Machine learning</li> </ul> The summer school will include lectures and hands-on sessions on the following topics: Molecular dynamics simulations Biomolecular docking Free energy calculations Advanced sampling methods (Metadynamics) BioExcel Building Blocks (BioBB) Quantum mechanics/molecular mechanics (QM/MM) Machine learning During the hands-on computer practicals you will make use of the BioExcel flagship software and tools: e.g. GROMACS, HADDOCK, PMX, BioBB, and CP2K. The trainers, developers and/or experts in the use of the software, will provide guidance and support. You can find more informatioan about the course on the BioExcel website: https://bioexcel.eu/events/bioexcel-summer-school-on-biomolecular-simulations-2022/https://bioexcel.eu/events/bioexcel-summer-school-on-biomolecular-simul…;

12 June - 17 June 2022

Humanized mice, personalized therapies and big data

Karl-Dimiter Bissig, Ernesto de la Cueva Bueno, Christian Münz, J.J. Schuringa, Leonard Shultz, Brian Soper, Renata Stripecke

<div class="vf-tabs"><ul class="vf-tabs__list" data-vf-js-tabs="true"><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-53de8397-0f08-449c-b4a4-0fdca47249f2" data-vf-js-location-nearest-activation-target="">Overview</a></li><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-speakers" data-vf-js-location-nearest-activation-target="">Speakers and Trainers</a></li><li class=& OverviewSpeakers and TrainersProgrammePractical InformationSponsors Overview Proof of COVID-19 vaccination or recovery is required to attend this on-site course. Please see EMBL’s COVID-19">https://www.embl.org/about/info/course-and-conference-office/?page_id=1… safety policy for on-site events. Course Overview Humanized mouse engraftment models (human immune system and/or human tissue) are an integral part of basic and translational research for the understanding of human diseases and for development of new therapies. The Ebola Virus outbreak has demonstrated the relevance of humanized mouse models for the understanding of emerging diseases and testing new medicines. The same can apply for the Coronavirus (COVID-19) pandemic. “Big pharma” and biotech companies include humanized mice in their pre-clinical development portfolio to test efficacy and safety of anti-cancer...

13 June - 17 June 2022

Summer school in bioinformatics

EMBL-EBI Training team

<p><span><span><span><span><span><span>This course, organised in association with </span></span></span>Wellcome Connecting Science<span><span><span>, provides an introduction to the use of bioinformatics in biological research, giving participants guidance for using bioinformatics in their work whilst also providing hands-on training in tools and resources appropriate to their research.</span></span></span></span></span></span></p> This course, organised in association with Wellcome Connecting Science, provides an introduction to the use of bioinformatics in biological research, giving participants guidance for using bioinformatics in their work whilst also providing hands-on training in tools and resources appropriate to their research. Participants will initially be introduced to bioinformatics theory and practice, including best practices for undertaking bioinformatics analysis, data management, and reproducibility. To enable specific exploration of resources in their particular field of interest, participants will be divided into focused groups to work on a project set by resource and data experts from EMBL-EBI and external collaborating institutes. These projects will end with a presentation from each group on the final day of the course to bring together learnings from all participants. Participants will be...

19 June - 22 June 2022

Defining and defeating metastasis

Johanna Joyce, Daniel Klimmeck, Joan Massagué, Charles Swanton

<div class="vf-tabs"><ul class="vf-tabs__list" data-vf-js-tabs="true"><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-53de8397-0f08-449c-b4a4-0fdca47249f2" data-vf-js-location-nearest-activation-target="">Overview</a></li><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-speakers" data-vf-js-location-nearest-activation-target="">Speakers</a></li><li class="vf-tabs_ OverviewSpeakersPreliminary ProgrammePractical InformationSponsorsAbout Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Proof of COVID-19 vaccination or recovery is required for on-site attendance. Please see EMBL’s COVID-19">https://www.embl.org/about/info/course-and-conference-office/?page_id=1… terms and conditions. Late on-site registration is still possible. For information please contact maria.bacadare@embl.de" data-type="mailto" data-id="mailto: maria.bacadare@embl.de">Maria Bacadare Symposium Overview This symposium will bring together researchers from diverse fields to enhance our understanding of the dissemination and metastatic colonisation of tumour cells. It will provide a unique opportunity for interdisciplinary exchange on current approaches and future collaborations on metastasis and its therapeutic challenges....

20 June - 24 June 2022

Cancer genomics

Jane Reynolds

<p>This course will focus on the analysis of data from genomic studies of cancer.&nbsp; Talks and interactive sessions&nbsp;will give an insight into the bioinformatic concepts required to analyse such data, whilst practical sessions will enable the participants to apply statistical methods to the analysis of cancer genomics data under the guidance of the trainers.</p> <h3>In-person course</h3> This course will focus on the analysis of data from genomic studies of cancer.  Talks and interactive sessions will give an insight into the bioinformatic concepts required to analyse such data, whilst practical sessions will enable the participants to apply statistical methods to the analysis of cancer genomics data under the guidance of the trainers. In-person course We plan to deliver this course in an in-person manner onsite at our training suite at EMBL-EBI, Hinxton.  Please be aware that we are continually evaluating the ongoing pandemic situation and, as such, may need to change the format of courses at short notice. Your safety is paramount to us; you can read our COVID">https://www.ebi.ac.uk/training/covid-policy">COVID guidance policy for more information. All information is correct at time of publishing.

21 June 2022

HPC boosts mathematical models’ promises of personalised medicine

Laurence Calzone, Arnau Montagud

<p>Mathematical models of the biological processes that are deregulated in diseases show a high complexity not only because of the number of genes and pathways involved, but also because of the numerous patients or samples to include in the simulations in order to be predictive. One way to address these issues is to combine High Performance Computer (HPC)-based methods to scale up the power of the computation with mechanistic and statistical modelling approaches.</p> Mathematical models of the biological processes that are deregulated in diseases show a high complexity not only because of the number of genes and pathways involved, but also because of the numerous patients or samples to include in the simulations in order to be predictive. One way to address these issues is to combine High Performance Computer (HPC)-based methods to scale up the power of the computation with mechanistic and statistical modelling approaches. In the context of the PerMedCoE project, we have brought together computer scientists and modellers to define the needs and the methods that need to be developed to optimise the simulations of these computationally-demanding models. Two use cases were defined: the first one describes a workflow that inputs omics data of cancer patients and outputs personalised combinations of drugs per patient based on a model of intracellular...

22 June 2022

An introduction to the COVID-19 Data Portal

Nadim Mahdi Rahman

<p><span><span><span><span><span><span>The </span></span></span></span></span></span><a href="https://www.covid19dataportal.org/"><span><span><span><span><span><span… Data Portal</span></span></span></span></span></span></span></span></a><span>&lt The COVID-19">https://www.covid19dataportal.org/"> Data Portal was launched in April 2020 to bring together relevant datasets and tools for sharing and analysis in an effort to accelerate coronavirus research. It enables researchers to upload, access and analyse COVID-19 related reference data and specialist datasets. This webinar will provide an introduction to the COVID-19 Data Portal, discuss the kind of data that is made available and include a demonstration of how to access data.

29 June - 1 July 2022

Timing mechanisms linking development and evolution

James Briscoe, Megan Davey, Miki Ebisuya, Pierre Vanderhaeghen

<div class="vf-tabs"><ul class="vf-tabs__list" data-vf-js-tabs="true"><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-53de8397-0f08-449c-b4a4-0fdca47249f2" data-vf-js-location-nearest-activation-target="">Overview</a></li><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-speakers" data-vf-js-location-nearest-activation-target="">Speakers</a></li><li class="vf-tabs_ OverviewSpeakersPreliminary ProgrammePractical InformationSponsors Overview This conference will take place at EMBL Barcelona. Proof of COVID-19 vaccination, recovery or negative test is required for on-site attendance. Please see EMBL’s https://www.embl.org/about/info/course-and-conference-office/covid-19-s…; target="_blank">COVID-19 safety policy for on-site events.  Conference Overview Time is inherent to biological processes. It determines the order of events and the speed at which they take place. This is particularly obvious during embryonic development where the sequence and rate of events ensures that structures develop in the right place, at the right time. Modifying the developmental tempo can affect the final size and composition of tissues, as well as their plasticity and function. Strikingly, comparisons between species reveals that, although the order and...

4 July - 15 July 2022

Visualising life – interdisciplinary approaches to biology

4 July - 8 July 2022

Systems biology: from large datasets to biological insight

Meredith Willmott

<p><span><span><span><span><span><span>This course covers the use of computational tools to extract biological insight from omics datasets. The content will explore a range of approaches - ranging from network inference and data integration to machine learning and logic modelling - that can be used to extract biological insights from varied data types. This course covers the use of computational tools to extract biological insight from omics datasets. The content will explore a range of approaches - ranging from network inference and data integration to machine learning and logic modelling - that can be used to extract biological insights from varied data types. Together these techniques will provide participants with a useful toolkit for designing new strategies to extract relevant information and understanding from large-scale biological data. The motivation for running this course is a result of advances in computer science and high-performance computing that have led to groundbreaking developments in systems biology model inference. With the comparable increase of publicly-available, large-scale biological data, the challenge now lies in interpreting them in a biologically valuable manner. Likewise, machine learning approaches are...

8 July - 15 July 2022

Super-resolution microscopy: time-resolved STED nanoscopy

Marco Lampe, Rainer Pepperkok, Ulf Schwarz

<div class="vf-tabs"><ul class="vf-tabs__list" data-vf-js-tabs="true"><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-53de8397-0f08-449c-b4a4-0fdca47249f2" data-vf-js-location-nearest-activation-target="">Overview</a></li><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-3d54115b-d5b4-44de-b390-a0fc833b1f12" data-vf-js-location-nearest-activation-target="">Speakers</a></li&gt OverviewSpeakersPreliminary ProgrammePractical InformationSponsors Overview EMBL is committed to sharing research advances and sustaining scientific interaction throughout the coronavirus pandemic. We are delighted to announce that the course is going virtual and invite you to join us online. Course Overview This six-day comprehensive microscopy course focuses on stimulated emission depletion microscopy (STED) and its application to biological questions. Through lectures, tutorials, demonstrations and practical workshops, the course provides in-depth knowledge on all aspects of STED Nanoscopy. It covers the fundamentals of STED microscopy, different technical implementations and has a strong emphasis on sample preparation – including choice of fluorophores and refractive index matching, as well as image acquisition strategies for fixed samples and living cells. Students will have the...

10 July - 14 July 2022

Bioinformatics for T-Cell immunology

Sophie Spencer

<p><span><span><span><span><span><span>This course will introduce and explore a number of key bioinformatics tools and resources that can be applied to T-cell immunological research. Targeted at life scientists with a wet-lab focus, it will provide participants with an overview of best-practice methods in applying bioinformatics approaches and enable them to become confident users of their own and public domain data. This course will introduce and explore a number of key bioinformatics tools and resources that can be applied to T-cell immunological research. Targeted at life scientists with a wet-lab focus, it will provide participants with an overview of best-practice methods in applying bioinformatics approaches and enable them to become confident users of their own and public domain data. The resources introduced during the course will cover a variety of data types, from genomic data to computational models, and biological pathways. Participants will gain experience of the analysis pipelines for RNA-Seq and flow cytometry experiments as well as data integration of -omics data and basics concepts of machine learning approaches.This course has been developed in collaboration with the ENLIGHT-TEN+http://www.enlight-ten.eu/">ENLIGHT…; project, a consortium focused on developing early-stage research...

11 July - 13 July 2022

Microfluidics 2022

Amy Herr, Christoph Merten, Angela Wu

<div class="vf-tabs"><ul class="vf-tabs__list" data-vf-js-tabs="true"><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-53de8397-0f08-449c-b4a4-0fdca47249f2" data-vf-js-location-nearest-activation-target="">Overview</a></li><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-speakers" data-vf-js-location-nearest-activation-target="">Speakers</a></li><li class="vf-tabs_ OverviewSpeakersPreliminary programmePractical InformationSponsors Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Proof of COVID-19 vaccination or recovery is required for on-site attendance. Please see EMBL’s COVID-19">https://www.embl.org/about/info/course-and-conference-office/?page_id=1… terms and conditions.  For late poster submission please contact Iva">mailto:iva.gavran@embl.de">Iva Gavran. Conference Overview Microfluidic tools have made recent biological and biomedical research leaps possible. At the physics, engineering, chemistry and biology interface, innovation in microfluidic approaches has positively impacted areas as diverse as nucleotide sequencing, functional genomics, single-cell and single-molecule studies, and biomedical diagnostics. Many of these applications – including next-generation sequencing...

17 July - 23 July 2022

C. elegans: from genome editing to imaging

Henrik Bringmann, Simone Köhler, Georgia Rapti, Pavak Shah

<div class="vf-tabs"><ul class="vf-tabs__list" data-vf-js-tabs="true"><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-53de8397-0f08-449c-b4a4-0fdca47249f2" data-vf-js-location-nearest-activation-target="">Overview</a></li><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-speakers" data-vf-js-location-nearest-activation-target="">Speakers and Trainers</a></li><li class=& OverviewSpeakers and TrainersPreliminary ProgrammePractical Information Overview Proof of COVID-19 vaccination or recovery is required to attend this on-site course. Please see EMBL’s COVID-19">https://www.embl.org/about/info/course-and-conference-office/?page_id=1… safety policy for on-site events. Course Overview C. elegans is a popular experimental model that combines transparency, reproducible anatomy, traceable cell lineage, sequenced genome and facile genetics, allowing to dissect animal development, physiology, and behaviour across scales of genes, cells and tissues. This 7-day course will present experimental practices in C. elegans research, while introducing historic and up-to-date findings in various research topics. Each day includes lectures, practicals, students flash-talks and interactive discussions with faculty. A series of methodologies commonly employed in C....

17 July - 21 July 2022

Proteomics bioinformatics

Juanita Riveros

<p>This course provides hands-on training in the basics of mass spectrometry (MS) and proteomics bioinformatics, search engines and post-processing software, quantitative approaches, MS data repositories, the use of public databases for protein analysis, annotation of subsequent protein lists, and incorporation of information from molecular interaction and pathway databases.</p> <p>This course is organised in association with the Vlaams Instituut voor Biotechnologie (VIB).</p> <h3>In-person course</h3> This course provides hands-on training in the basics of mass spectrometry (MS) and proteomics bioinformatics, search engines and post-processing software, quantitative approaches, MS data repositories, the use of public databases for protein analysis, annotation of subsequent protein lists, and incorporation of information from molecular interaction and pathway databases. This course is organised in association with the Vlaams Instituut voor Biotechnologie (VIB). In-person course We plan to deliver this course in an in-person manner onsite at our training suite at EMBL-EBI, Hinxton.  Please be aware that we are continually evaluating the ongoing pandemic situation and, as such, may need to change the format of courses at short notice. Your safety is paramount to us; you can read our COVID">https://www.ebi.ac.uk/training/covid-policy">COVID guidance policy for more...

17 July - 20 July 2022

Innate immunity in host-pathogen interactions

Bernhard Hube, Julie Pfeiffer, Felix Randow, Feng Shao, Cyril Zipfel

<div class="vf-tabs"><ul class="vf-tabs__list" data-vf-js-tabs="true"><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-53de8397-0f08-449c-b4a4-0fdca47249f2" data-vf-js-location-nearest-activation-target="">Overview</a></li><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-speakers" data-vf-js-location-nearest-activation-target="">Speakers</a></li><li class="vf-tabs_ OverviewSpeakersPreliminary ProgrammePractical InformationSponsorsAbout Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Proof of COVID-19 vaccination or recovery is required for on-site attendance. Please see EMBL’s COVID-19">https://www.embl.org/about/info/course-and-conference-office/?page_id=1… terms and conditions.  Symposium Overview This symposium provides a discussion platform for all scientists interested in the biology of infection. Cell biologists, microbiologists and immunologists will discuss in joint sessions recent progress in our understanding of host-pathogen interactions. Talks will focus on common processes, rather than particular infectious agents or host cell types, and the strategies of all major types of pathogens in their interaction with plants and animals will be covered. A better understanding of...

21 August - 29 August 2022

Advances in cryo-electron microscopy and 3D image processing

Julia Mahamid, Sebastian Eustermann, Simone Mattei, Lori Passmore, Henning Stahlberg

<div class="vf-tabs"><ul class="vf-tabs__list" data-vf-js-tabs="true"><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-53de8397-0f08-449c-b4a4-0fdca47249f2" data-vf-js-location-nearest-activation-target="">Overview</a></li><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-speakers" data-vf-js-location-nearest-activation-target="">Speakers and Trainers</a></li><li class=& OverviewSpeakers and TrainersPreliminary ProgrammePractical InformationSponsors Overview Proof of COVID-19 vaccination or recovery is required to attend this on-site course. Please see EMBL’s https://www.embl.org/about/info/course-and-conference-office/?page_id=1…; data-type="URL" data-id="COVID-19">https://www.embl.org/about/info/course-and-conference-office/?page_id=1… safety policy for on-site events. Course Overview Cryo-electron microscopy (cryoEM) has become the method of choice for determining atomic-level structures of large and flexible macromolecular assemblies that are notoriously difficult to study by other techniques. In addition, it has unique capabilities for obtaining structural information in situ, within complex (cellular) environments, and to deal with biologically heterogeneous samples. With the advent of the cryoEM “resolution revolution”, the method has...

27 August - 30 August 2022

Transcription and chromatin

Karen Adelman, Eileen Furlong, Jürg Müller, Peter Verrijzer

<div class="vf-tabs"><ul class="vf-tabs__list" data-vf-js-tabs="true"><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-53de8397-0f08-449c-b4a4-0fdca47249f2" data-vf-js-location-nearest-activation-target="">Overview</a></li><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-speakers" data-vf-js-location-nearest-activation-target="">Speakers</a></li><li class="vf-tabs_ OverviewSpeakersPreliminary ProgrammePractical InformationSponsors Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Proof of COVID-19 vaccination or recovery is required for on-site attendance. Please see EMBL’s COVID-19">https://www.embl.org/about/info/course-and-conference-office/?page_id=1… terms and conditions. Conference Overview The EMBL Transcription and Chromatin meeting has a long-standing tradition in shaping the field of transcriptional regulation. The meeting brings together leading experts covering all aspects of transcription including cis-regulatory function, long range regulation, 3-dimensional looping, the basal transcriptional machinery, RNA polymerase regulation and function, nucleosome positioning, chromatin modifications, chromatin remodelling and epigenetic inheritance of transcriptional silencing. The meeting...

4 September - 13 September 2022

Current methods in cell biology

Sara Cuylen-Häring, Simone Köhler

<div class="vf-tabs"><ul class="vf-tabs__list" data-vf-js-tabs="true"><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-53de8397-0f08-449c-b4a4-0fdca47249f2" data-vf-js-location-nearest-activation-target="">Overview</a></li><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-speakers" data-vf-js-location-nearest-activation-target="">Speakers and Trainers </a></li><li class= OverviewSpeakers and Trainers Preliminary ProgrammePractical InformationSponsors Overview Proof of COVID-19 vaccination or recovery is required to attend this on-site course. Please see EMBL’s https://www.embl.org/about/info/course-and-conference-office/?page_id=1…; data-type="URL" data-id="COVID-19">https://www.embl.org/about/info/course-and-conference-office/?page_id=1… safety policy for on-site events. Course Overview Experience modern cell biology at work: not only see but also try out in practice how cutting-edge technologies can be used to answer questions at the frontiers of cell biology. It is a tradition that the entire faculty of the Cell Biology and Biophysics Unit of EMBL teaches the course to cover a broad spectrum of techniques. The course also provides an excellent opportunity for participants and course faculty to discuss current and future challenges in cell...

5 September - 12 September 2022

Membrane protein expression, purification and characterization (mPEPC2)

<div class="vf-tabs"><ul class="vf-tabs__list" data-vf-js-tabs="true"></ul><div class="vf-tabs-content" data-vf-js-tabs-content="true"></div></div> If you are not automatically redirected, please click">https://meetings.embo.org/event/22-mpepc2">click here to visit the event website.

5 September - 8 September 2022

Chemical biology 2022

Yimon Aye, Claire Deo, Kai Johnsson, Edward Lemke

<div class="vf-tabs"><ul class="vf-tabs__list" data-vf-js-tabs="true"><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-53de8397-0f08-449c-b4a4-0fdca47249f2" data-vf-js-location-nearest-activation-target="">Overview</a></li><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-speakers" data-vf-js-location-nearest-activation-target="">Speakers</a></li><li class="vf-tabs_ OverviewSpeakersPreliminary ProgrammePractical InformationSponsors Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Proof of COVID-19 vaccination or recovery is required for on-site attendance. Please see EMBL’s COVID-19">https://www.embl.org/about/info/course-and-conference-office/?page_id=1… terms and conditions. Conference Overview The conference sets the stage for the dissemination and exchange of new developments in diverse, hot fields within chemical biology. It is the largest and longest standing conference in the field, being a platform for inspiration, collaboration and networking for researchers in academia and industry. We aim to provide the possibility for every chemical biologist to meet and discuss with peers topics ranging from tool development to biological applications, from computational drug design to...

11 September - 18 September 2022

Synthetic biology in action: beyond standard metabolism

Sven Panke, Vitor Pinheiro, Karen Polizzi, Elisabeth Zielonka

<div class="vf-tabs"><ul class="vf-tabs__list" data-vf-js-tabs="true"><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-53de8397-0f08-449c-b4a4-0fdca47249f2" data-vf-js-location-nearest-activation-target="">Overview</a></li><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-speakers" data-vf-js-location-nearest-activation-target="">Speakers and Trainers</a></li><li class=& OverviewSpeakers and TrainersPreliminary ProgrammePractical InformationSponsors Overview Proof of COVID-19 vaccination or recovery is required to attend this on-site course. Please see EMBL’s COVID-19">https://www.embl.org/about/info/course-and-conference-office/?page_id=1… safety policy for on-site events. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Course Overview Synthetic Biology (SynBio) has become a rapidly developing area for tackling a large number of challenges in life science research. This is due to a combination of foundational advances in technologies such as large-scale DNA synthesis and new methods that allow integrating such raw synthesis power into engineering approaches, including genome wide small RNA regulation, dCas9-based regulation, and multiplexed genome engineering. Such...

11 September - 12 September 2022

Organisation and utilisation of hologenomic datasets

Charlotte Pearton

<p>This course will cover the generation and application of large-scale holo-omic data sets, such as those produced within the <a href="https://www.holofood.eu/">HoloFood</a&gt; project.</p> This course will cover the generation and application of large-scale holo-omic data sets, such as those produced within the HoloFoodhttps://www.holofood.eu/">HoloFood; project. There is an increasing recognition that organisms do not exist in isolation, but are actually holobionts, composed of the host and the many microorganisms found on or in the individual. The HoloFood project has developed significant multi-omics datasets for both chicken and salmon, with a view to understanding how different feeds impact the gut microbiota, and in turn animal productivity. This course covers how to access and utilise both raw and derived data products, the workflow to achieve genome-resolved metagenomics, analysis of host variation, generation and interpretation of metabolomic data, and approaches to multi-omic integration to understand links between traits and genomic information. The HoloFood...

12 September - 16 September 2022

Mathematics of life: modelling molecular mechanisms

Juanita Riveros

<p><span><span><span><span>This course will provide participants with an introduction and hands-on training on modelling approaches, tools and resources used in systems biology as well as touch on network analysis.</span></span></span></span></p> This course will provide participants with an introduction and hands-on training on modelling approaches, tools and resources used in systems biology as well as touch on network analysis. Computer models are increasingly used to understand the essential processes of biology. Researchers in academic institutions as well as the pharmaceutical industry use mathematical models to generate hypotheses on how complex biomolecular systems work. Modelling of biochemical pathways deregulated in disease conditions can offer mechanistic insights into the pathology, help to elucidate mechanisms behind drug action, and predict the dose required for treatment thus facilitating fundamental research and drug discovery. This course will provide a helpful brief introduction to key modelling concepts and hands on training to use popular tools and resources used in this scientific field. In-person course We...

13 September - 16 September 2022

Reconstructing the human past: using ancient and modern genomics

Johannes Krause, Anna-Sapfo Malaspinas, Ida Moltke, David Reich

<div class="vf-tabs"><ul class="vf-tabs__list" data-vf-js-tabs="true"><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-53de8397-0f08-449c-b4a4-0fdca47249f2" data-vf-js-location-nearest-activation-target="">Overview</a></li><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-speakers" data-vf-js-location-nearest-activation-target="">Speakers and Organisers</a></li><li class OverviewSpeakers and OrganisersPreliminary ProgrammePractical InformationSponsorsAbout Overview Symposium Overview Combining genome-wide data from ancient and modern populations opens new windows into the past. Population-scale sequencing projects investigating past and present human diversity have already provided us with extraordinary insights into patterns of human variation and mobility through time and space. The available dataset of genome-wide data from modern humans has approximately tripled since the first edition of ‘Reconstructing the human past: using ancient and modern genomics’ in 2019, and the ability to carry out further large-scale studies on the scale of whole cemeteries and deeply sampled time transects makes it now possible to ask and answer questions that were simply impossible to address before. The integration of archaeological evidence and historical...

19 September - 24 September 2022

Imaging down to single-molecule resolution: STED and MINFLUX nanoscopy

Marko Lampe, Julia Menzel, Christian Wurm, Timo Zimmermann

<div class="vf-tabs"><ul class="vf-tabs__list" data-vf-js-tabs="true"><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-53de8397-0f08-449c-b4a4-0fdca47249f2" data-vf-js-location-nearest-activation-target="">Overview</a></li><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-speakers" data-vf-js-location-nearest-activation-target="">Speakers and Trainers</a></li><li class=& OverviewSpeakers and TrainersPreliminary Programme Practical Information Overview Proof of COVID-19 vaccination or recovery is required to attend this on-site course. Please see EMBL’s COVID-19">https://www.embl.org/about/info/course-and-conference-office/?page_id=1… safety policy for on-site events. Course overview The course aims to train biological microscopy users in two forms of super-resolution light microscopy, Stimulated Emission Depletion (STED) Microscopy and Minimal photon fluxes (MINFLUX). Both techniques require technical understanding of the process and instrumentation, training in the method specific requirements of sample preparation and in the acquisition procedures and an understanding of how to further analyze the acquired image data. It is the aim of the course to provide the tools for the successful execution of nanoscopy experiments with these two distinct...

20 September - 23 September 2022

Integrative analysis of multi-omics data

Wolfgang Huber, Oliver Stegle, Britta Velten

<div class="vf-tabs"><ul class="vf-tabs__list" data-vf-js-tabs="true"><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-53de8397-0f08-449c-b4a4-0fdca47249f2" data-vf-js-location-nearest-activation-target="">Overview</a></li><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-speakers" data-vf-js-location-nearest-activation-target="">Speakers and Trainers</a></li><li class=& OverviewSpeakers and TrainersProgrammePractical InformationSponsors Overview Proof of COVID-19 vaccination or recovery is required to attend this on-site course. Please see EMBL’s COVID-19">https://www.embl.org/about/info/course-and-conference-office/?page_id=1… safety policy for on-site events. This course has been postponed from February 2022 and the selection process is finalised. Applications will not be re-opened. Course Overview Multi-omics studies that combine genomics, transcriptome, proteome and other modalities are increasingly common in fundamental biology research and biomedicine. Using multi-omics experimental designs at bulk or single-cell resolution can help identifying novel biomarkers or reveal insights into biological mechanisms. This course addresses the conceptual and mathematical foundations of state-of-the-art methods for analyzing the data that results from...

27 September - 30 September 2022

Bioinformatics and functional genomics in zebrafish

Meredith Willmott

<p><span><span><span><span><span><span>Zebrafish are widely used to study development, toxicity and disease, and functional genomics is used throughout the field to identify new pathways and mechanisms, and for comparison to other model systems and humans. In this hands-on course, participants will learn how to design functional genomics experiments, manage and analyse RNA-seq datasets from zebrafish, and compare results to other species. Zebrafish are widely used to study development, toxicity and disease, and functional genomics is used throughout the field to identify new pathways and mechanisms, and for comparison to other model systems and humans. In this hands-on course, participants will learn how to design functional genomics experiments, manage and analyse RNA-seq datasets from zebrafish, and compare results to other species. The aim of the course is to equip researchers with tools to carry out functional analysis and data visualisation of RNA-seq data that has already been mapped to the genome and been analysed for differential gene expression. The course will be relevant to researchers working on a wide range of topics and will use real datasets from our lab for hands-on analysis. Please note that this course will not teach the initial steps of RNA-seq analysis but instead start at the point that you have a...

3 October - 7 October 2022

Single-cell RNA-seq analysis using R

Jane Reynolds

<p>This course covers the analysis of scRNA-seq data using R and command line tools. Participants will be guided through droplet-based&nbsp;scRNA-seq analysis pipelines from raw reads to cell clusters. They will explore and interpret data using R as well as the <a href="https://www.ebi.ac.uk/gxa/sc/home">Single Cell Expression Atlas</a>. Finally, participants will put their knowledge into practice through a group challenge on the last two days of the course.</p> This course covers the analysis of scRNA-seq data using R and command line tools. Participants will be guided through droplet-based scRNA-seq analysis pipelines from raw reads to cell clusters. They will explore and interpret data using R as well as the Single">https://www.ebi.ac.uk/gxa/sc/home">Single Cell Expression Atlas. Finally, participants will put their knowledge into practice through a group challenge on the last two days of the course. Please note that participants will not analyse their own data as part of the course. There will, however, be ample opportunity to discuss their research and ideas with other course participants and trainers. Virtual course Participants will learn via a mix of pre-recorded lectures, live presentations, and trainer Q&A sessions. Practical experience will be developed through group activities and trainer-led computational exercises....

5 October - 8 October 2022

Molecular mechanisms in evolution and ecology

Gianni Liti, Sara Mitri, Kiran Patil, Kimberley Kline, Antonis Rokas

<div class="vf-tabs"><ul class="vf-tabs__list" data-vf-js-tabs="true"><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-53de8397-0f08-449c-b4a4-0fdca47249f2" data-vf-js-location-nearest-activation-target="">Overview</a></li><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-speakers" data-vf-js-location-nearest-activation-target="">Speakers</a></li><li class="vf-tabs_ OverviewSpeakersPreliminary ProgrammePractical InformationSponsors Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Proof of COVID-19 vaccination or recovery is required for on-site attendance. Please see EMBL’s COVID-19">https://www.embl.org/about/info/course-and-conference-office/?page_id=1… safety policy for on-site events.  Conference Overview This conference series has become known for exploring yeasts as models to study questions of general relevance to evolution and ecology. Experts will speak on a range of topics, including evolution theory, ecology, genetics, cell biology, genomics, systems biology, metabolic modelling and engineering. The focus of this conference will be on comparative and experimental strategies to explore evolutionary questions, from field studies to computer simulations to comparative genomics....

9 October - 14 October 2022

Genome engineering: CRISPR/Cas from cells to mice

N. Humphreys, B. Koch, P. Rajakannu, E. Zielonka

<div class="vf-tabs"><ul class="vf-tabs__list" data-vf-js-tabs="true"><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-53de8397-0f08-449c-b4a4-0fdca47249f2" data-vf-js-location-nearest-activation-target="">Overview</a></li><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-sponsors" data-vf-js-location-nearest-activation-target="">Sponsors</a></li></ul><div class=&q OverviewSponsors Overview Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Course Overview This course will provide training in genome editing and cell engineering in mammalian cells and mouse embryos using the highly efficient CRISPR/Cas9 system. Participants will learn design of CRISPR targets using bioinformatics tools, generation of gene knock-outs/knock-ins, and target validation using the most current technologies. The course will be split into two groups (mammalian cells OR mice) based on participants’ expertise. Please note that all participants are expected to engage in all sessions. Particpants should plan for approximately 1 hour extra per day for self paced learning modules. Audience This course is aimed at researchers who are familiar with basic molecular and cell biology...

12 October - 15 October 2022

The complex life of RNA

Anne Ephrussi, Wendy V. Gilbert, Torben Heick Jensen, Ramesh Pillai

<div class="vf-tabs"><ul class="vf-tabs__list" data-vf-js-tabs="true"><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-53de8397-0f08-449c-b4a4-0fdca47249f2" data-vf-js-location-nearest-activation-target="">Overview</a></li><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-c09bd6fc-0bf9-4be9-981e-461103679a9b" data-vf-js-location-nearest-activation-target="">Speakers</a></li&gt OverviewSpeakersProgrammePractical InformationSponsorsAbout Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Proof of COVID-19 vaccination or recovery is required for on-site attendance. Please see EMBL’s COVID-19">https://www.embl.org/about/info/course-and-conference-office/?page_id=1… safety policy for on-site events.  Conference Overview Before the genetic information stored in DNA can be used to direct cell growth and metabolism, it has to be transferred into RNA. Messenger RNAs (mRNAs) that code for proteins and noncoding RNAs are key components in the transmission of genetic information in all life forms – from viruses to complex mammalian organisms. Exciting recent findings now reveal a new layer of information added to RNAs in the form of chemical marks (the epitranscriptome) that play a critical role in gene...

16 October - 21 October 2022

Metabolite and species dynamics in microbial communities

Sandeep Krishna, Sunil Krishna, Kiran Patil, Elisabeth Zielonka, Maria Zimmermann

<div class="vf-tabs"><ul class="vf-tabs__list" data-vf-js-tabs="true"><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-53de8397-0f08-449c-b4a4-0fdca47249f2" data-vf-js-location-nearest-activation-target="">Overview</a></li><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-speakers" data-vf-js-location-nearest-activation-target="">Speakers and Trainers</a></li><li class=& OverviewSpeakers and TrainersPreliminary ProgrammePractical InformationSponsors Overview Course Overview Metagenomics studies are rapidly uncovering the compositional richness of microbial communities in diverse habitats ranging from the oceans to the human gut. While their fundamental role in our health and environment is undeniable, there is an urgent need for unravelling molecular mechanisms underlying the dynamics of these communities. This requires a combined experimental and computational approach. Recent studies (including those from the organisers’ and speakers’ labs) have underlined the success of such integrative approaches. For example, emergence of cell subpopulations (Varahan et al. eLife 2019, 2020), and long-term stability (Blasche, Kim et al. Nat Microbiol. 2021) through metabolic cross-feeding. As researchers world-wide map species dynamics in the ecosystems of their...

17 October - 21 October 2022

Bioinformatics approaches to viruses

Sophie Spencer

<p>This workshop will provide training on the use of bioinformatics tools to understand viral pathogens’ sequencing data. Trainees will receive training on viral genome assembly, comparative viral genomics, phylogenomics, metaviromics, and downstream applications of this data in research and applied contexts.</p> This workshop will provide training on the use of bioinformatics tools to understand viral pathogens’ sequencing data. Trainees will receive training on viral genome assembly, comparative viral genomics, phylogenomics, metaviromics, and downstream applications of this data in research and applied contexts.

17 October - 21 October 2022

Structural bioinformatics

Juanita Riveros

<p>A guide to the commonly used methods and tools in structural bioinformatics to analyse and interpret experimentally determined and AI-predicted macromolecular structure data.</p> A guide to the commonly used methods and tools in structural bioinformatics to analyse and interpret experimentally determined and AI-predicted macromolecular structure data. Structural biology, determining the three-dimensional shapes of biomacromolecules and their complexes, can tell us a lot about how these molecules function and the roles they play within a cell. Data derived from structure determination experiments and Artificial Intelligence (AI)-assisted structure prediction enables life-science researchers to address a wide variety of questions.   This virtual course explores bioinformatics data resources and tools for the investigation, analysis, and interpretation of both experimentally determined and predicted biomacromolecular structures. It will focus on how best to analyse and interpret available structural data to gain useful information given specific research...

26 October - 29 October 2022

Plasticity across scales: from molecules to phenotypes

Ehab Abouheif, Alexander Aulehla, Axel Meyer, Sonia Sultan

<div class="vf-tabs"><ul class="vf-tabs__list" data-vf-js-tabs="true"><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-53de8397-0f08-449c-b4a4-0fdca47249f2" data-vf-js-location-nearest-activation-target="">Overview</a></li><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-speakers" data-vf-js-location-nearest-activation-target="">Speakers</a></li><li class="vf-tabs_ OverviewSpeakersPreliminary ProgrammePractical InformationSponsorsAbout Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Proof of COVID-19 vaccination or recovery is required for on-site attendance. Please see EMBL’s COVID-19">https://www.embl.org/about/info/course-and-conference-office/?page_id=1… terms and conditions. Symposium Overview This symposium aims to bring together a diverse group of scientists to discuss phenotypic, developmental and transgenerational plasticity from a wide range of disciplines and perspectives, focusing on its underlying molecular mechanisms and its role in driving evolutionary novelty. The meeting is designed to provide an interactive platform for scientists who share a common interest in plasticity but usually do not meet, within an intensive conference setting.  Speakers...

30 October - 4 November 2022

The fundamentals of high-end cell sorting

Derek Davis, Andrew Filby, Diana Ordoñez-Rueda, Malte Paulsen, Steffen Schmitt

<div class="vf-tabs"><ul class="vf-tabs__list" data-vf-js-tabs="true"><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-53de8397-0f08-449c-b4a4-0fdca47249f2" data-vf-js-location-nearest-activation-target="">Overview</a></li><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-sponsors" data-vf-js-location-nearest-activation-target="">Sponsors</a></li></ul><div class=&q OverviewSponsors Overview Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Course Overview This course on the fundamentals of high-end cell sorting will enable scientists to properly use the global upstream technology of cell sorting with high confidence. Cell sorting is essential to many studies, but researchers outside of core facilities have very limited knowledge how exactly sorting works and unknowingly produce erroneous samples or even scientifically crippling data. Audience The course is intended for PhD students and postdocs who are starting to use, or already using flow cytometry based cell sorting in their research projects. Applicants with some previous active knowledge of basic principles of flow cytometry and a regular use of flow cytometers in daily research will profit most from the content of...

31 October - 4 November 2022

Genome-resolved metagenomics bioinformatics

Meredith Willmott

<p><span><span><span><span><span><span>Learn about the tools, processes and analysis approaches used in the field of genome-resolved metagenomics.</span></span></span></span></span></span></p> Learn about the tools, processes and analysis approaches used in the field of genome-resolved metagenomics. This course will cover the use of publicly available resources to manage, share, analyse and interpret metagenomics data, focussing primarily on assembly-based approaches. The virtually-delivered content will involve participants learning via pre-recorded lectures and live presentations, followed by live Q&As with the trainers. Practical experience will be developed in group activities and in computational exercises run using containerised tools on our virtual training infrastructure.   Participants will need to be available between the hours of 09:00-17:00 GMT each day of the course.

4 November 2022

EMBL in Spain 2022

EMBL Alumni Relations

<div class="wp-block-group"><div class="wp-block-group__inner-container"></div></div> <p>If you are not redirected automatically, <a href="https://www.embl.org/about/info/alumni/blog/events/embl-in-spain-2022/"… click here to visit the event website. </a></p> If you are not redirected automatically, please">https://www.embl.org/about/info/alumni/blog/events/embl-in-spain-2022/"… click here to visit the event website.

7 November - 10 November 2022

The neurovascular interface

Amparo Acker-Palmer, Ralf Adams, Chenghua Gu

<div class="vf-tabs"><ul class="vf-tabs__list" data-vf-js-tabs="true"><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-53de8397-0f08-449c-b4a4-0fdca47249f2" data-vf-js-location-nearest-activation-target="">Overview</a></li><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-speakers" data-vf-js-location-nearest-activation-target="">Speakers</a></li><li class="vf-tabs_ OverviewSpeakersPreliminary ProgrammePractical InformationSponsorsAbout Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Proof of COVID-19 vaccination or recovery is required for on-site attendance. Please see EMBL’s COVID-19">https://www.embl.org/about/info/course-and-conference-office/?page_id=1… terms and conditions. Symposium Overview Neurovascular biology is a young, emerging field that aims to unravel the molecular communication between the nervous system and the vasculature. Both the nervous system and the vascular system share striking conceptual similarities in the assembly of cellular networks through guided growth and branching processes. Vascular and neural cells work together to form a number of functional tissue compartments. Endothelial cells, certain mural support cells (i.e., pericytes), astrocytes and neurons...

11 November - 13 November 2022

Practical integrative structural biology

<div class="vf-tabs"><ul class="vf-tabs__list" data-vf-js-tabs="true"><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-0ca76819-6802-4cdd-9510-363cc44515b0" data-vf-js-location-nearest-activation-target="">Tab 1</a></li></ul><div class="vf-tabs-content" data-vf-js-tabs-content="true"> Tab 1 Tab 1

13 November - 18 November 2022

Single-cell omics: deeper to genomics

Qiaolin Deng, Jan O. Korbel, Anders Ståhlberg, Elisabeth Zielonka

<div class="vf-tabs"><ul class="vf-tabs__list" data-vf-js-tabs="true"><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-53de8397-0f08-449c-b4a4-0fdca47249f2" data-vf-js-location-nearest-activation-target="">Overview</a></li><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-sponsors" data-vf-js-location-nearest-activation-target="">Sponsors</a></li></ul><div class=&q OverviewSponsors Overview Proof of COVID-19 vaccination or recovery is required to attend this on-site course. Please see EMBL’s COVID-19">https://www.embl.org/about/info/course-and-conference-office/?page_id=1… safety policy for on-site events. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Course Overview Single-cell analysis is a rapidly evolving approach and is increasingly implemented in various research fields. The numerous workflows contain several critical and challenging steps from cell sampling over working with minute amounts of sample to data analysis and integration. This hands-on course will cover latest cutting-edge techniques in single cell genomics (Strand-Seq), single cell epigenetics (single-cell bisulfite sequencing) and microdroplet based single-cell transcriptomics (scRNA-Seq)...

14 November - 18 November 2022

Genome bioinformatics: resequencing and variant calling

Jane Reynolds

<p><span><span><span><span><span><span>A guide to the technology, analysis workflows, tools, and resources for next generation sequencing data analysis.</span></span></span></span></span></span></p> A guide to the technology, analysis workflows, tools, and resources for next generation sequencing data analysis. This virtual course will provide insights and training into how biological knowledge can be derived from genomics experiments and explain different approaches in analysing such data. The main focus will be on introducing sequence informatics, re-sequencing, and variant calling during the analysis of higher-eukaryotes, with an emphasis on human genetic research. Throughout the week, more advanced topics will introduce the creation of pipelines, automation, and the scaling-up of analysis experiments. Practical sessions will enable participants to process training datasets and apply appropriate statistical methods in their analyses. There will be no opportunity to work with personal research data during the course. Virtual course Participants will learn via a mix of pre-recorded...

15 November - 18 November 2022

From functional genomics to systems biology

Arnaud Krebs, Prisca Liberali, Mikhail Savitski, Georg Seelig

<div class="vf-tabs"><ul class="vf-tabs__list" data-vf-js-tabs="true"><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-53de8397-0f08-449c-b4a4-0fdca47249f2" data-vf-js-location-nearest-activation-target="">Overview</a></li><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-speakers" data-vf-js-location-nearest-activation-target="">Speakers</a></li><li class="vf-tabs_ OverviewSpeakersPreliminary ProgrammePractical InformationSponsors Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Proof of COVID-19 vaccination or recovery is required for on-site attendance. Please see EMBL’s COVID-19">https://www.embl.org/about/info/course-and-conference-office/?page_id=1… safety policy for on-site events.  Conference Overview Genomics, proteomics and quantitative imaging are rapidly moving fields with technological innovations and new biological insights occurring on an almost monthly basis. For example, mass spectrometry-based proteomics is now able to quantitatively assess close to 80% of the proteome which can nowadays be obtained from very low cell numbers. An even greater jump in sensitivity has recently revolutionized genomics with the rapid spread of measurements at the resolution of single...

23 November - 25 November 2022

Managing a bioinformatics core facility

Sophie Spencer

<p><span><span><span><span><span><span>This knowledge exchange workshop is an opportunity for managers of bioinformatics core facilities to learn from EMBL-EBI’s service teams, and from each other. These facilities play an essential role in enabling research in the molecular life sciences. This knowledge exchange workshop is an opportunity for managers of bioinformatics core facilities to learn from EMBL-EBI’s service teams, and from each other. These facilities play an essential role in enabling research in the molecular life sciences. The landscape is constantly evolving as new research tools emerge, as experiments become increasingly data intensive, and as their clients – experimental researchers – become more exposed to the power of data-driven biology. This course will allow participants to share experiences, discuss challenges and solutions that they face, and plan ways to cope with the ever changing demands raised by the molecular life science field. It will include sessions to learn from data providers at EMBL-EBI, hear how others have tackled common problems, and work together to design core services.

29 November - 2 December 2022

Protein quality control for downstream processes

Karine Lapouge, Kim Remans

<div class="vf-tabs"><ul class="vf-tabs__list" data-vf-js-tabs="true"><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-53de8397-0f08-449c-b4a4-0fdca47249f2" data-vf-js-location-nearest-activation-target="">Overview</a></li><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-speakers" data-vf-js-location-nearest-activation-target="">Speakers and Trainers</a></li><li class=& OverviewSpeakers and TrainersPreliminary ProgrammePractical InformationSponsors Overview Proof of COVID-19 vaccination or recovery is required to attend this on-site course. Please see EMBL’s COVID-19">https://www.embl.org/about/info/course-and-conference-office/?page_id=1… safety policy for on-site events. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Course Overview Purified proteins are used in various types of scientific experiments and fields. For example, in structural biology insights into the functional mechanisms can be obtained by elucidating the 3D molecular structure of proteins and protein complexes using technologies such as X-ray crystallography, cryo-EM and NMR. In biochemistry and biophysics, interactions with other proteins, nucleic acids and small molecules can be studied by...

7 December 2022

EMBL in Israel 2022

EMBL Alumni Relations

<div class="wp-block-group"><div class="wp-block-group__inner-container"></div></div> If you are not redirected automatically, please">https://www.embl.org/about/info/alumni/blog/events/embl-in-israel-2022/… click here to visit the event website.https://www.embl.org/about/info/alumni/blog/events/embl-in-spain-2022/"…;

24 January - 27 January 2023

Computing skills for reproducible research: data carpentry

Renato Alves, Lisanna Paladin, Fotis Psomopoulos, Christian Schudoma

<div class="vf-tabs"><ul class="vf-tabs__list" data-vf-js-tabs="true"><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-53de8397-0f08-449c-b4a4-0fdca47249f2" data-vf-js-location-nearest-activation-target="">Overview</a></li><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-sponsors" data-vf-js-location-nearest-activation-target="">Sponsors</a></li></ul><div class=&q OverviewSponsors Overview Proof of COVID-19 vaccination or recovery is required to attend this on-site course. Please see EMBL’s COVID-19">https://www.embl.org/about/info/course-and-conference-office/?page_id=1… safety policy for on-site events. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Course overview The missing step between data collection and research progress is a lack of training for researchers in crucial skills for effectively managing and analysing large amounts of data. This hands-on workshop teaches researchers the fundamental data skills they need to conduct their work and provides high-quality, domain-specific training covering the full lifecycle of data-driven research. The domain-specific approach allows participants to tailor the data, content, and tools to reflect the specific...

8 February - 11 February 2023

In situ structural biology: from cryo-EM to integrative modelling

Martin Beck, Jan Kosinski, Julia Mahamid, Suliana Manley

<div class="vf-tabs"><ul class="vf-tabs__list" data-vf-js-tabs="true"><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-53de8397-0f08-449c-b4a4-0fdca47249f2" data-vf-js-location-nearest-activation-target="">Overview</a></li><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-sponsors" data-vf-js-location-nearest-activation-target="">Sponsors</a></li></ul><div class=&q OverviewSponsors Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Proof of COVID-19 vaccination or recovery is required for on-site attendance. Please see EMBL’s COVID-19">https://www.embl.org/about/info/course-and-conference-office/?page_id=1… safety policy for on-site events. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Conference overview There is an increasing awareness that mechanistic structural information on molecular machines is ideally generated within the context of intact cells in order to fully grasp how they function in a complex native environment. Recent technological advances have nurtured the development of such in situ structural biology approaches in several disciplines, including cryo-EM, mass spectrometry,...

12 February - 17 February 2023

High-accuracy CLEM: application at room temperature and in cryo

Ori Avinoam, Rachel Mellwig, Martin Schorb

<div class="vf-tabs"><ul class="vf-tabs__list" data-vf-js-tabs="true"><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-53de8397-0f08-449c-b4a4-0fdca47249f2" data-vf-js-location-nearest-activation-target="">Overview</a></li><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-sponsors" data-vf-js-location-nearest-activation-target="">Sponsors</a></li></ul><div class=&q OverviewSponsors Overview Proof of COVID-19 vaccination or recovery is required to attend this on-site course. Please see EMBL’s COVID-19">https://www.embl.org/about/info/course-and-conference-office/?page_id=1… safety policy for on-site events. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Course overview Correlative Light and Electron Microscopy (CLEM) allows precise localisation of an event of interest within cells and tissues. During this course, we will focus on a specific method that has been developed at EMBL that enables the location of fluorescent proteins with high accuracy at the ultrastructural level. The course will cover both the theory and practicals of high precision CLEM, as well as opportunities to discuss their research with CLEM experts and receive practical and...

26 February - 3 March 2023

Analysis and integration of transcriptome and proteome data

Vladimir Benes, Raffaele Calogero, Jeroen Krijgsveld, Lennart Martens

<div class="vf-tabs"><ul class="vf-tabs__list" data-vf-js-tabs="true"><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-53de8397-0f08-449c-b4a4-0fdca47249f2" data-vf-js-location-nearest-activation-target="">Overview</a></li><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-sponsors" data-vf-js-location-nearest-activation-target="">Sponsors</a></li></ul><div class=&q OverviewSponsors Overview Proof of COVID-19 vaccination or recovery is required to attend this on-site course. Please see EMBL’s COVID-19">https://www.embl.org/about/info/course-and-conference-office/?page_id=1… safety policy for on-site events. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Course overview Systems biology is a still expanding field of research aiming to understand at the molecular level how cells, tissues and organisms operate in their biological context. Among the key technologies driving this forward are next-generation sequencing and proteomics, as they provide powerful means to determine global expression levels of genes and proteins. Both fields have matured to a degree that they have now become accessible to researchers in many areas of biology. During this course, participants...

12 March - 17 March 2023

Extracellular vesicles: from biology to biomedical applications

An Hendrix, Cecilia Lässer, Esther Noltet Hoen, Guillaume Van Niel

<div class="vf-tabs"><ul class="vf-tabs__list" data-vf-js-tabs="true"><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-53de8397-0f08-449c-b4a4-0fdca47249f2" data-vf-js-location-nearest-activation-target="">Overview</a></li><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-sponsors" data-vf-js-location-nearest-activation-target="">Sponsors</a></li></ul><div class=&q OverviewSponsors Overview Proof of COVID-19 vaccination or recovery is required to attend this on-site course. Please see EMBL’s COVID-19">https://www.embl.org/about/info/course-and-conference-office/?page_id=1… safety policy for on-site events. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Course overview A rapidly increasing number of researchers aim to purify and identify extracellular vesicles and many methodologies to isolate and analyse these vesicles are available and have been implemented. This course will cover the basics, possibilities and limitations of different purification and characterisation techniques and will address strategies to understand their role in biomedical applications. Audience This course is intended for PhD students and Postdoctoral researchers who are interested in...

26 March - 1 April 2023

Measuring translational dynamics by ribosome profiling

Pavel Baranov, Sebastian Leidel, Jan Medenbach, Elisabeth Zielonka

<div class="vf-tabs"><ul class="vf-tabs__list" data-vf-js-tabs="true"><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-53de8397-0f08-449c-b4a4-0fdca47249f2" data-vf-js-location-nearest-activation-target="">Overview</a></li><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-sponsors" data-vf-js-location-nearest-activation-target="">Sponsors</a></li></ul><div class=&q OverviewSponsors Overview Proof of COVID-19 vaccination or recovery is required to attend this on-site course. Please see EMBL’s COVID-19">https://www.embl.org/about/info/course-and-conference-office/?page_id=1… safety policy for on-site events. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Course overview Regulation of translation is key in the control of gene expression, playing a critical role in many biological and pathophysiological settings. In the last decade, methodological advances have provided comprehensive insights into cellular transcriptomes and proteomes, however, the systems-wide analysis of translation remained an unsolved experimental challenge. The advent of ‘ribosome-profiling’ provided the methodological basis for comprehensive transcriptome-wide analyses of translation at...

25 April - 28 April 2023

Brain genome: regulation, evolution and function

Roberto Bonasio, Matthieu Boulard, Magdalena Götz, Kyung-Min Noh

<div class="vf-tabs"><ul class="vf-tabs__list" data-vf-js-tabs="true"><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-53de8397-0f08-449c-b4a4-0fdca47249f2" data-vf-js-location-nearest-activation-target="">Overview</a></li><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-sponsors" data-vf-js-location-nearest-activation-target="">Sponsors</a></li><li class="vf-tabs_ OverviewSponsorsAbout Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Proof of COVID-19 vaccination or recovery is required for on-site attendance. Please see EMBL’s COVID-19">https://www.embl.org/about/info/course-and-conference-office/?page_id=1… safety policy for on-site events. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Symposium overview This symposium will explore how the brain genome is regulated in order to support neural function and neural plasticity. We will consider various viewpoints on this question in the form of topical sessions in order to best cover the most exciting research being done at the moment in this area. We will explore how genome evolution has contributed to speciation, how genome architecture impacts neural plasticity,...

15 May - 18 May 2023

Chromatin and epigenetics

<div class="vf-tabs"><ul class="vf-tabs__list" data-vf-js-tabs="true"><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-53de8397-0f08-449c-b4a4-0fdca47249f2" data-vf-js-location-nearest-activation-target="">Overview</a></li><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-sponsors" data-vf-js-location-nearest-activation-target="">Sponsors</a></li></ul><div class=&q OverviewSponsors Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Proof of COVID-19 vaccination or recovery is required for on-site attendance. Please see EMBL’s COVID-19">https://www.embl.org/about/info/course-and-conference-office/?page_id=1… safety policy for on-site events. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Conference overview Epigenetics refers to heritable changes in gene expression that do not involve changes to the underlying DNA sequence. At least three systems including DNA methylation, histone modifications and non-coding RNAs (ncRNA) are considered to play fundamental roles in epigenetic regulation. Research over the last two decades has uncovered the role of epigenetics in a variety of human disorders and fatal diseases....

23 May - 25 May 2023

BioMalPar XIX: biology and pathology of the malaria parasite

<div class="vf-tabs"><ul class="vf-tabs__list" data-vf-js-tabs="true"><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-53de8397-0f08-449c-b4a4-0fdca47249f2" data-vf-js-location-nearest-activation-target="">Overview</a></li><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-sponsors" data-vf-js-location-nearest-activation-target="">Sponsors</a></li></ul><div class=&q OverviewSponsors Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Proof of COVID-19 vaccination or recovery is required for on-site attendance. Please see EMBL’s COVID-19">https://www.embl.org/about/info/course-and-conference-office/?page_id=1… safety policy for on-site events. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Conference overview Malaria remains one of the most significant global public health challenges, with more than 200 million clinical cases worldwide each year. The lack of a vaccine that provides effective long-term protection and the continual emergence of drug-resistant malaria parasites emphasises the need for new control and prevention strategies. This need for innovation has become even more apparent with the disruption of global...

4 June - 7 June 2023

The ageing genome: from mechanisms to disease

Jacqueline Jacobs, Gaëlle Legube, Brian Luke, Björn Schumacher

<div class="vf-tabs"><ul class="vf-tabs__list" data-vf-js-tabs="true"><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-53de8397-0f08-449c-b4a4-0fdca47249f2" data-vf-js-location-nearest-activation-target="">Overview</a></li><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-sponsors" data-vf-js-location-nearest-activation-target="">Sponsors</a></li><li class="vf-tabs_ OverviewSponsorsAbout Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Proof of COVID-19 vaccination or recovery is required for on-site attendance. Please see EMBL’s COVID-19">https://www.embl.org/about/info/course-and-conference-office/?page_id=1… safety policy for on-site events. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Symposium overview This symposium will explore the central position of the genome and the maintenance of its integrity in the multifaceted phenomenon that we know as ageing.  Sponsors Sponsorship opportunities We offer a variety of event sponsoring possibilities, with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget. Discounts are available for...

12 June - 15 June 2023

Life at the periphery: mechanobiology of the cell surface

Alba Diz Muñoz, Zemer Gitai, KC Huang, Ewa Paluch

<div class="vf-tabs"><ul class="vf-tabs__list" data-vf-js-tabs="true"><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-53de8397-0f08-449c-b4a4-0fdca47249f2" data-vf-js-location-nearest-activation-target="">Overview</a></li><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-sponsors" data-vf-js-location-nearest-activation-target="">Sponsors</a></li><li class="vf-tabs_ OverviewSponsorsAbout Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Proof of COVID-19 vaccination or recovery is required for on-site attendance. Please see EMBL’s COVID-19">https://www.embl.org/about/info/course-and-conference-office/?page_id=1… safety policy for on-site events. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Symposium overview The cell surface – comprising the plasma membrane, the underlying cortical cytoskeleton and in many cell types a cell wall – is a central integrator of cell form and function. Its physico-chemical properties are rapidly modulated to accommodate or drive changes in shape or behaviour and to exchange matter and information with the environment. This symposium will bring together researchers from different...

27 June - 30 June 2023

New approaches and concepts in microbiology

Pascale Cossart, Sophie Helaine, K.C. Huang, Michael Laub, Nassos Typas

<div class="vf-tabs"><ul class="vf-tabs__list" data-vf-js-tabs="true"><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-53de8397-0f08-449c-b4a4-0fdca47249f2" data-vf-js-location-nearest-activation-target="">Overview</a></li><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-sponsors" data-vf-js-location-nearest-activation-target="">Sponsors</a></li></ul><div class=&q OverviewSponsors Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Proof of COVID-19 vaccination or recovery is required for on-site attendance. Please see EMBL’s COVID-19">https://www.embl.org/about/info/course-and-conference-office/?page_id=1… safety policy for on-site events. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Symposium overview This symposium will cover a broad range of topics in microbiology, including antibiotic-related research, bacterial communities and microbiome, cell biology, regulation & signalling, pathogenesis and evolution. Emphasis will be placed on novel approaches and technologies (from systems-based to single-cell) that drive each field or have the potential to revolutionise future research in microbiology. This meeting...

11 July - 14 July 2023

Predicting evolution

Justin Crocker

<div class="vf-tabs"><ul class="vf-tabs__list" data-vf-js-tabs="true"><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-53de8397-0f08-449c-b4a4-0fdca47249f2" data-vf-js-location-nearest-activation-target="">Overview</a></li><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-sponsors" data-vf-js-location-nearest-activation-target="">Sponsors</a></li></ul><div class=&q OverviewSponsors Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Proof of COVID-19 vaccination or recovery is required for on-site attendance. Please see EMBL’s COVID-19">https://www.embl.org/about/info/course-and-conference-office/?page_id=1… safety policy for on-site events. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Conference overview Advances in genome sequencing and gene editing tools are providing unprecedented insights into biological mechanisms and evolutionary processes. In parallel, computational and theoretical approaches are providing new insights into our understanding of these new data. A goal for this conference is to unite people across theoretical and experimental backgrounds into a coherent focus on “predicting evolution”. The...

16 July - 21 July 2023

Drosophila genetics and genomics

Casey Bergman, Justin Crocker

<div class="vf-tabs"><ul class="vf-tabs__list" data-vf-js-tabs="true"><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-53de8397-0f08-449c-b4a4-0fdca47249f2" data-vf-js-location-nearest-activation-target="">Overview</a></li><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-sponsors" data-vf-js-location-nearest-activation-target="">Sponsors</a></li></ul><div class=&q OverviewSponsors Overview Proof of COVID-19 vaccination or recovery is required to attend this on-site course. Please see EMBL’s COVID-19">https://www.embl.org/about/info/course-and-conference-office/?page_id=1… safety policy for on-site events. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Course overview The fruit fly Drosophila has played a leading role in the discovery and dissection of basic biological processes, uncovering general principles of development, evolution and disease. Almost a century of research has generated a powerful genetic toolbox that provides a unique arsenal of methods that can tackle almost any biological question. This, combined with exciting new technologies developed in recent years have changed the way Drosophila research is conducted, enabling biologists to address...

20 September - 23 September 2023

The human microbiome

<div class="vf-tabs"><ul class="vf-tabs__list" data-vf-js-tabs="true"><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-53de8397-0f08-449c-b4a4-0fdca47249f2" data-vf-js-location-nearest-activation-target="">Overview</a></li><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-sponsors" data-vf-js-location-nearest-activation-target="">Sponsors</a></li></ul><div class=&q OverviewSponsors Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Proof of COVID-19 vaccination or recovery is required for on-site attendance. Please see EMBL’s COVID-19">https://www.embl.org/about/info/course-and-conference-office/?page_id=1… safety policy for on-site events. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Symposium overview Human microbiota – the collection of microbes living in and on our body – have a significant impact on human health and well-being. They have been associated with numerous diseases, yet we have barely understood their role in the context of life-style and genetics. Various initiatives are underway around the world to survey the human microbiota at several body sites, characterise them, understand their...

4 October - 7 October 2023

Seeing is believing: imaging the molecular processes of life

Jan Ellenberg, Jennifer Lippincott-Schwartz, Atsushi Miyawaki

<div class="vf-tabs"><ul class="vf-tabs__list" data-vf-js-tabs="true"><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-53de8397-0f08-449c-b4a4-0fdca47249f2" data-vf-js-location-nearest-activation-target="">Overview</a></li><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-sponsors" data-vf-js-location-nearest-activation-target="">Sponsors</a></li><li class="vf-tabs_ OverviewSponsorsAbout Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Proof of COVID-19 vaccination or recovery is required for on-site attendance. Please see EMBL’s COVID-19">https://www.embl.org/about/info/course-and-conference-office/?page_id=1… safety policy for on-site events. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Symposium overview The molecular processes of life are naturally dynamic in space and time from the atomic to the organismal level. The rapid development of imaging methods across the full scale of biological organisation is revolutionising our ability to visualise the inner workings of macromolecular complexes, organelles, cells, tissues, organs and whole organisms. Being able to see biological processes unfold in real time...

11 October - 14 October 2023

The non-coding genome

Marc Buehler, Anna Eulalio, Joshua Mendell, Gisela Storrz, Igor Ulitsky

<div class="vf-tabs"><ul class="vf-tabs__list" data-vf-js-tabs="true"><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-53de8397-0f08-449c-b4a4-0fdca47249f2" data-vf-js-location-nearest-activation-target="">Overview</a></li><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-sponsors" data-vf-js-location-nearest-activation-target="">Sponsors</a></li><li class="vf-tabs_ OverviewSponsorsAbout Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Proof of COVID-19 vaccination or recovery is required for on-site attendance. Please see EMBL’s COVID-19">https://www.embl.org/about/info/course-and-conference-office/?page_id=1… safety policy for on-site events. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Symposium overview This symposium will explore the diverse, dynamic and multifaceted roles of RNA across a spectrum of cellular processes. It will provide an interdisciplinary discussion of the roles of non-coding RNAs in both prokaryotes and eukaryotes, with the aim of enhancing our understanding of gene regulation and function. In the 50 years since RNA was identified as a central component in the flow of genetic information,...

25 October - 27 October 2023

Proteomics in cell biology and disease mechanisms

<div class="vf-tabs"><ul class="vf-tabs__list" data-vf-js-tabs="true"><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-53de8397-0f08-449c-b4a4-0fdca47249f2" data-vf-js-location-nearest-activation-target="">Overview</a></li><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-sponsors" data-vf-js-location-nearest-activation-target="">Sponsors</a></li></ul><div class=&q OverviewSponsors Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Proof of COVID-19 vaccination or recovery is required for on-site attendance. Please see EMBL’s COVID-19">https://www.embl.org/about/info/course-and-conference-office/?page_id=1… safety policy for on-site events. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Conference overview The 6th Proteomics in Cell Biology and Disease Mechanisms conference will again be held in association with EMBL-EBI and the Wellcome Genome Campus. The field of proteomics continues to develop rapidly due to technological and computational advances in high-throughput methods and multi-omics big data integration. This year’s programme will focus on medical and clinical applications of proteomics,...

8 November - 11 November 2023

The mobile genome: genetic and physiological impacts of transposable elements

<div class="vf-tabs"><ul class="vf-tabs__list" data-vf-js-tabs="true"><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-53de8397-0f08-449c-b4a4-0fdca47249f2" data-vf-js-location-nearest-activation-target="">Overview</a></li><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-sponsors" data-vf-js-location-nearest-activation-target="">Sponsors</a></li></ul><div class=&q OverviewSponsors Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Proof of COVID-19 vaccination or recovery is required for on-site attendance. Please see EMBL’s COVID-19">https://www.embl.org/about/info/course-and-conference-office/?page_id=1… safety policy for on-site events. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Conference overview This conference is assembling world-leading experts from diverse fields including genomics, epigenetics, structural biology, developmental biology, immunology, cancer biology and neurobiology, to discuss the broad impacts of TEs on organismal biology. This conference provides a venue for cross-disciplinary discussions, with the goal of catalysing inter-disciplinary collaborations to address emerging questions in...

13 November - 17 November 2023

Hands-on flow cytometry: learning by doing!

Andrew Filby, Diana Ordonez, Malte Paulsen, Steffen Schmitt

<div class="vf-tabs"><ul class="vf-tabs__list" data-vf-js-tabs="true"><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-53de8397-0f08-449c-b4a4-0fdca47249f2" data-vf-js-location-nearest-activation-target="">Overview</a></li><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-sponsors" data-vf-js-location-nearest-activation-target="">Sponsors</a></li></ul><div class=&q OverviewSponsors Overview Proof of COVID-19 vaccination or recovery is required to attend this on-site course. Please see EMBL’s COVID-19">https://www.embl.org/about/info/course-and-conference-office/?page_id=1… safety policy for on-site events. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Course overview ShFlow Cytometry is one of the most powerful single cell analysis methods used throughout the life sciences and medicine. By utilising Flow Cytometry we can identify and quantify specific cell populations from heterogeneous samples, analyse the cell cycle or proliferation state or simply detect the expression of fluorescent reporters. In line with the suggestions from our course in 2019, we will significantly enhance the number of analysis sessions together with our partners from FlowJo. We will...

15 November - 17 November 2023

Cancer genomics

<div class="vf-tabs"><ul class="vf-tabs__list" data-vf-js-tabs="true"><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-53de8397-0f08-449c-b4a4-0fdca47249f2" data-vf-js-location-nearest-activation-target="">Overview</a></li><li class="vf-tabs__item"><a class="vf-tabs__link" href="#vf-tabs__section-sponsors" data-vf-js-location-nearest-activation-target="">Sponsors</a></li></ul><div class=&q OverviewSponsors Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Proof of COVID-19 vaccination or recovery is required for on-site attendance. Please see EMBL’s COVID-19">https://www.embl.org/about/info/course-and-conference-office/?page_id=1… safety policy for on-site events. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Conference overview This conference will provide an opportunity to learn about and keep up to date with the rapidly progressing area of cancer genomics. It will cover presentations from cancer genome projects, the areas of cancer functional genomics, systems biology, cancer immunogenomics and epigenomics, cancer mouse models and the translation and clinical impact of obtained scientific results. The meeting will bring together leading...