EMBL Events

EMBL delivers world-class courses, conferences and workshops at the forefront of molecular life science and its applications.

Browse upcoming events below, or learn more about training at EMBL.

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26 May - 31 May 2024

Whole transcriptome data analysis

26 May 20242024CourseEMBL Heidelberg

Marco Beccuti, Vladimir Benes, Raffaele Calogero, Francesca Cordero

This course will teach the biological researchers how to analyse biological data sets using open source software Most of the analysis will be performed with docker4seq and rCASC packages which was developed to facilitate the use of computing demanding applications in the field of NGS data analysis... OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview Course overview This course will teach the biological researchers how to analyse biological data sets using open-source software. Most of the analysis will be performed with docker4seq and rCASC packages, which was developed to facilitate the use of computing demanding applications in the field of NGS data analysis. Docker4seq and rCASC packages use docker containers that embed demanding computing tasks (e.g. short reads mapping) into isolated containers. This approach provides multiple advantages: the user does not need to install all the software on its local server, the results generated by different containers can be organised in pipelines and reproducible research is guarantee by the possibility of sharing the docker images used for the analysis. Computers for hands-on exercises will be provided along with demo...

Course

EMBL Heidelberg

Registration
Closed

1 June - 8 June 2024

Structural characterisation of macromolecular complexes

1 June 20242024CourseEMBL Grenoble

Ana Casanal, Wojciech Galej, Eva Kowalinski, Carlo Petosa, Montserrat Soler López

OverviewSpeakers and trainersPreliminary programmePractical informationSponsorsMedia kit Overview Course overview Recent developments in cryo EM ET super resolution microscopy and protein structure prediction coupled with increasingly sophisticated methods of sample preparation have revolutionised structural biology Educating the next generation of researchers on how to strategically... OverviewSpeakers and trainersPreliminary programmePractical informationSponsorsMedia kit Overview Course overview Recent developments in cryo-EM/ET, super-resolution microscopy, and protein structure prediction — coupled with increasingly sophisticated methods of sample preparation — have revolutionised structural biology. Educating the next generation of researchers on how to strategically combine these disparate tools is critical for addressing the most challenging structural biology problems of the future. Course participants will receive a comprehensive overview of state-of-the-art structural methods, with a focus on sample preparation, characterisation, and data integration strategies. Key aspects covered by lectures and practicals include multi-subunit protein expression in bacteria, insect, and mammalian cells; isolation of native complexes and in-vitro reconstitution of protein...

EMBO Practical Course

EMBL Grenoble

Registration
Closed

5 June - 8 June 2024

Microtubules: from atoms to complex systems

5 June 20242024ConferenceEMBL Heidelberg, Virtual

Carsten Janke, Thomas Müller-Reichert, Shinsuke Niwa, Kassandra Ori-Mckenney

In recent years interdisciplinary approaches embracing cell biology genetics molecular biology biochemistry biophysics structural biology and mathematical modelling have made a tremendous impact on the microtubule field... OverviewSpeakersProgrammeAboutPractical infomationSponsorsMedia kit Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Symposium overview This symposium, initiated in 2010, has taken place every second year since and brings together early-career and established researchers from all over the world who are interested in microtubule biology and its impact on human health and disease. The microtubule cytoskeleton is essential for a wide variety of cellular functions, such as chromosome segregation, directed vesicle and organelle transport, cell motility, and cell polarity. Impaired microtubule function can lead to human diseases including cancer and neurodegenerative disorders, where microtubules serve as important therapeutic targets. In recent years, interdisciplinary approaches embracing cell biology, genetics, molecular biology,...

EMBO | EMBL Symposium

EMBL Heidelberg, Virtual

Registration (Virtual)
29 May 2024
Registration (On-site)
Closed
Abstract submission
Closed

7 June 2024

AlphaMissense predictions for human genetic variation research

7 June 20242024WebinarVirtual

This webinar will explore AlphaMissense a model based on AlphaFold AlphaMissense is designed to analyse missense variants which are individual amino acid changes in proteins Classifying these variants is crucial for understanding which ones might contribute to disease development Our guest speaker from Google DeepMind will introduce AlphaMissense You ll gain insights into its underlying technology how it analyses variants and what the generated scores represent Importantly all predictions from AlphaMissense are freely available to the scientific community The webinar will then showcase how EMBL EBI resources integrate AlphaMissense data This includes details on how the data is stored displayed and accessed by researchers studying human genetic variations We will conclude by a question and answer session with all the presenters... This webinar will explore AlphaMissense, a model based on AlphaFold. AlphaMissense is designed to analyse missense variants, which are individual amino acid changes in proteins. Classifying these variants is crucial for understanding which ones might contribute to disease development.Our guest speaker from Google DeepMind will introduce AlphaMissense. You'll gain insights into its underlying technology, how it analyses variants, and what the generated scores represent. Importantly, all predictions from AlphaMissense are freely available to the scientific community.The webinar will then showcase how EMBL-EBI resources integrate AlphaMissense data. This includes details on how the data is stored, displayed, and accessed by researchers studying human genetic variations.We will conclude by a question and answer session with all the presenters.

Webinar

Virtual


9 June - 15 June 2024

C. elegans: from genome editing to imaging

9 June 20242024CourseEMBL Heidelberg

Henrik Bringmann, Simone Koehler, Georgia Rapti, Pavak Shah

OverviewSpeakersPreliminary ProgrammePractical informationSponsorsMedia kit Overview Course overview C elegans is a popular experimental model that combines transparency reproducible anatomy traceable cell lineage sequenced genome and facile genetics allowing to dissect animal development physiology and behaviour across scales of genes cells and tissues This 7 day course will... OverviewSpeakersPreliminary ProgrammePractical informationSponsorsMedia kit Overview Course overview C. elegans is a popular experimental model that combines transparency, reproducible anatomy, traceable cell lineage, sequenced genome and facile genetics, allowing to dissect animal development, physiology, and behaviour across scales of genes, cells and tissues. This 7-day course will present experimental practices in C. elegans research, while introducing historic and up-to-date findings in various research topics. Each day includes lectures, practicals, student poster presentations and interactive discussions with faculty. Various methodologies commonly employed in C. elegans research will be presented in parallel practicals with rotating student groups by relevant experts. These experimental techniques span forward and reverse genetics, genome editing, lineaging, imaging approaches...

EMBO Practical Course

EMBL Heidelberg

Registration
Closed

10 June - 14 June 2024

Systems biology: from large datasets to biological insight

10 June 20242024CourseEMBL-EBI

Juanita Riveros

This course covers the use of computational tools to extract biological insight from omics datasets The content will explore a range of approaches ranging from network inference and data integration to machine learning and logic modelling that can be used to extract biological insights from varied data types Together these techniques will provide participants with a useful toolkit for designing new strategies to extract relevant information and understanding from large scale biological data The motivation for running this course is a result of advances in computer science and high performance computing that have led to groundbreaking developments in systems biology model inference With the comparable increase of publicly available large scale biological data the challenge now lies in interpreting them in a biologically valuable manner Likewise machine learning approaches are making a significant impact in our analysis of large omics datasets and the extraction of useful biological knowledge... This course covers the use of computational tools to extract biological insight from omics datasets. The content will explore a range of approaches – ranging from network inference and data integration to machine learning and logic modelling – that can be used to extract biological insights from varied data types. Together these techniques will provide participants with a useful toolkit for designing new strategies to extract relevant information and understanding from large-scale biological data.The motivation for running this course is a result of advances in computer science and high-performance computing that have led to groundbreaking developments in systems biology model inference. With the comparable increase of publicly-available, large-scale biological data, the challenge now lies in interpreting them in a biologically valuable manner. Likewise, machine learning approaches are...

Course

EMBL-EBI

Registration
Closed

17 June - 21 June 2024

Summer school in bioinformatics

17 June 20242024CourseEMBL-EBI

Barbara Etzi

Thank you to those of you who have applied we have now selected our participants and wait list There are no more spaces available Please register your interest for the 2025 course here Details of the 2024 course can be found below This course provides an introduction to the use of bioinformatics in biological research giving you guidance for using bioinformatics in your work whilst also providing hands on training in tools and resources appropriate to your research You will initially be introduced to bioinformatics theory and practice including best practices for undertaking bioinformatics analysis data management and reproducibility You will be required to review some pre recorded material for their group project prior to the start of the course Group projectsA major element of this course is a group project where you ll be placed in small groups to work together on a challenge set by trainers from EMBL EBI and external institutes This allows you to explore the bioinformatics tools and resources available in your area of interest and apply them to a set problem providing you with hands on experience relevant to your own research The group work will culminate in a presentation session involving everyone on the final day of the course giving an opportunity for wider discussion on the benefits and challenges of working with biological data Groups are mentored and supported by the trainers who set the initial challenge but the groups will be responsible for driving their projects forward with all members expected to take an active role Groups are pre organised before the course and all group members will be sent some short homework in preparation for your project work prior to the start of the course Basic outlines of the projects on offer this year are given below In your application you must indicate your first and second choice of project based on which you think would benefit your research most Not all projects may be offered and final decisions on which projects will be run during the course will be made based on the number of applicants per project Most of the projects cover mammalian data sets however in many cases the methods and approaches taught are transferable to data from various species Group project one Genome variation across human populations Natural variation between individuals or between different human populations is a result of genome mutations throughout evolutionary history Some mutations may become fixed because of their beneficial effect while most drift among individuals During this project you will investigate genomic variation between two separate human populations of European and Asian descent Using sequence data from a number of individuals from each population you will use a range of bioinformatics tools to discover variants that exist between them In the second section of the project you will attempt to analyse the functional consequences of the variants you have identified attempting to find clinical association and linking them to phenotypes Project mentor Anu Shivalikanjli EMBL EBI Group project two Interpreting functional information from large scale protein structure dataThis project will introduce you to the wealth of publicly available data in the Protein Data Bank PDB and give you the opportunity to investigate how large subsets of structure data can be used to analyse protein features and determine function In the project you will learn how to identify relevant protein structures collate and interpret functional information and implement this process programmatically Project mentor Marcus Bage EMBL EBI and Joseph Ellaway EMBL EBIGroup project three Modelling cell signalling pathwaysCurating models of biological processes is an effective training in computational systems biology where the curators gain an integrative knowledge of biological systems modelling and bioinformatics You will learn to encode and simulate ordinary differential equation models of signalling pathways from a recent publication using user friendly software such as COPASI even without extensive mathematical background You will learn to perform in silico experiments new predictions and develop hypotheses Furthermore you will learn how to annotate models and re use pre existing models from open repositories such as BioModels Project mentors Rahuman Sheriff EMBL EBI and Krishna Tiwari EMBL EBI Group project four Improving AI based bioimage analysis Artificial Intelligence AI algorithms outperform classical image analysis methods however the performance of these models is highly dependent on the quality of the annotated image datasets used to train them In this project you will explore the application of AI for biological imaging and the relationship between model training data and model performance You will use models stored in the BioImage Model Zoo and data in the BioImage Archive to fine tune and aggregate AI outputs The aim of this project will be to test evaluate and improve model performance on a diverse set of microscopy images and annotations within the BioImage Archive You will learn how to apply train tune and employ the most performant state of the art computer vision models This project serves as a valuable demonstration of how FAIR Findable Accessible Interoperable Reusable data plays an essential role in the training and enhancement of AI models Project mentors Aybuke Kupcu Yoldas EMBL EBI and Craig Russel EMBL EBI Group project five Single cell RNA sequencing analysis with PythonIn this project you will learn how to perform single cell RNA sequencing data analysis to investigate cell type heterogeneity and expression differences across conditions The analysis will be based on the SCANPY framework in Python You will start by collecting the raw count matrix and relevant metadata from the Single cell Expression Atlas After constructing the AnnData objects you will perform quality control preprocessing dimensionality reduction cell type annotation and differential expression analysis We will also explore the batch effect and its correction Project mentors Yuyao Song EMBL EBI and Anna Vathrakokoili Pournara EMBL EBI Group project six Networks and pathwaysThis project will cover typical bioinformatics analysis steps needed to put differentially expressed genes into a wider biological context You will start with gene expression data RNA seq to build an initial interaction network Next you will learn to combine public network datasets identify key regulators of biological pathways and explore biological function through network analysis You will get first hand experience in integration and co visualising with additional data and functional enrichment analysis All this helps to put the initial results into a previously known context and provide hypotheses for potential follow up experiments We will use Cytoscape Expression Atlas g Profiler StringDb among other tools We may also give a few R packages a try Project mentor Priit Adler University of Tartu... Thank you to those of you who have applied, we have now selected our participants and wait list. There are no more spaces available. Please register your interest for the 2025 course here.Details of the 2024 course can be found below.This course provides an introduction to the use of bioinformatics in biological research, giving you guidance for using bioinformatics in your work whilst also providing hands-on training in tools and resources appropriate to your research.You will initially be introduced to bioinformatics theory and practice, including best practices for undertaking bioinformatics analysis, data management, and reproducibility. You will be required to review some pre-recorded material for their group project prior to the start of the course.Group projectsA major element of this course is a group project, where you'll be placed in small groups to work together on a...

Course

EMBL-EBI

Registration
Closed

18 June - 21 June 2024

Innate immunity in host-pathogen interactions

18 June 20242024ConferenceEMBL Heidelberg, Virtual

Gordon Brown, Michaela Gack, Felix Randow, Dominique Soldati-Favre, Cyril Zipfel

OverviewSpeakersPreliminary programmePractical informationSponsorsAboutMedia kit Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Symposium overview This follow up meeting to the successful EMBO EMBL Symposia Innate immunity in Host Pathogen Interactions in 2016 2018 and 2022 will provide a discussion and networking platform for all... OverviewSpeakersPreliminary programmePractical informationSponsorsAboutMedia kit Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Symposium overview This follow-up meeting to the successful EMBO | EMBL Symposia ‘Innate immunity in Host Pathogen Interactions’ in 2016, 2018 and 2022 will provide a discussion and networking platform for all scientists interested in the biology of pathogen infection. The symposium will promote the exchange of conceptual ideas in this rapidly evolving field, and also foster cross-disciplinary collaborations among the scientists. Innate immunity is studied by both microbiologists and immunologists; however, their perspectives differ widely. Microbiologists are necessarily specialists for their pathogen(s) of choice, while immunologists tend to focus on the host response. The goal of the conference is...

EMBO | EMBL Symposium

EMBL Heidelberg, Virtual

Registration (Virtual)
11 June 2024
Registration (On-site)
Closed
Abstract submission
Closed

24 June - 28 June 2024

Cancer genomics and transcriptomics

24 June 20242024CourseVirtual

Meredith Willmott

This course will focus on the analysis of data from genomic studies of cancer It will also highlight the application of transcriptomic analysis and single cell technologies in cancer Talks and interactive sessions will give an insight into the bioinformatic concepts required to analyse such data whilst practical sessions will enable the participants to apply statistical methods to the analysis of cancer genomics data under the guidance of the trainers Virtual courseParticipants will learn via a mix of pre recorded lectures live presentations and trainer Q A sessions Practical experience will be developed through group activities and trainer led computational exercises Live sessions will be delivered using Zoom with additional support and asynchronous communication via Slack Pre recorded material may be provided before the course starts that participants will need to watch read or work through to gain the most out of the actual training event In the week before the course there will be a brief induction session Computational practicals will run on EMBL EBI s virtual training infrastructure meaning participants will not require access to a powerful computer or install complex software on their own machines Participants will need to be available between the hours of 08 45 17 00 BST each day of the course Trainers will be available to assist answer questions and provide further explanations during these times... This course will focus on the analysis of data from genomic studies of cancer. It will also highlight the application of transcriptomic analysis and single-cell technologies in cancer. Talks and interactive sessions will give an insight into the bioinformatic concepts required to analyse such data, whilst practical sessions will enable the participants to apply statistical methods to the analysis of cancer genomics data under the guidance of the trainers.Virtual courseParticipants will learn via a mix of pre-recorded lectures, live presentations, and trainer Q&A sessions. Practical experience will be developed through group activities and trainer-led computational exercises. Live sessions will be delivered using Zoom with additional support and asynchronous communication via Slack.Pre-recorded material may be provided before the course starts that participants will need to watch,...

Course

Virtual

Registration
Closed

1 July - 5 July 2024

Bioinformatics for immunologists

1 July 20242024CourseEMBL-EBI

Juanita Riveros

This course will provide participants with an introduction to a range of bioinformatics resources and approaches applicable to immunological research Participants will gain experience in analysis pipelines for NGS experiments relevant to immunology including immune receptor sequencing RNA sequencing single cell RNA sequencing and flow cytometry data analysis Additionally participants will be introduced to how data from several sources can be integrated to provide a wider view of their research thereby enabling them to be more confident users of their own data and that from public sources... This course will provide participants with an introduction to a range of bioinformatics resources and approaches applicable to immunological research. Participants will gain experience in analysis pipelines for NGS experiments relevant to immunology including immune receptor sequencing, RNA sequencing, single-cell RNA sequencing, and flow cytometry data analysis.Additionally, participants will be introduced to how data from several sources can be integrated to provide a wider view of their research, thereby enabling them to be more confident users of their own data and that from public sources.

Course

EMBL-EBI

Registration
Closed

4 July - 5 July 2024

From atoms to ecosystems – a new era in life sciences

4 July 20242024ConferenceEMBL Heidelberg, Virtual

Rolf Apweiler, Elena Conti, Anne Ephrussi, Eileen Furlong, Cornelius Gross, Rainer Pepperkok, Pavel Tomancak, Nassos Typas

OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview The symposium will take place at EMBL Heidelberg and is open to EMBL staff and alumni Registration for the onsite event is only via the link in the invitation email The option to join virtually is open to all To take part in the symposium virtually please register via the button on this page Conference overview... OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview The symposium will take place at EMBL Heidelberg and is open to EMBL staff and alumni. Registration for the onsite event is only via the link in the invitation email. The option to join virtually is open to all. To take part in the symposium virtually please register via the button on this page. Conference overview In 2024, EMBL will celebrate its 50th anniversary with a historic two-day scientific symposium. This colloquium, ‘From atoms to ecosystems – a new era in life sciences’, will be held both virtually and in-person at Heidelberg on Thursday 4 – Friday 5 July 2024. The event will celebrate EMBL from the moment of its inception, in 1974 when the proposal to bring a world-class life sciences laboratory to Europe was ratified, through to the exciting and vibrant organisation that EMBL represents today. The...

EMBL 50th Anniversary Scientific Symposium

EMBL Heidelberg, Virtual

Registration
27 June 2024

8 July - 12 July 2024

Time-resolved macromolecular serial crystallography

8 July 20242024CourseEMBL Grenoble

Oskar Aurelius, Shibom Basu, Gisela Brändé, Arwen Pearson, Daniele de Sanctis

OverviewSpeakers and trainersPreliminary programmePractical informationSponsorsMedia kit Overview Course overview The advent of serial crystallography at free electron laser sources and the following adaptation of these methods at 3rd and 4th generation synchrotrons have opened new possibilities to perform room temperature time resolved studies in macromolecular crystallography This... OverviewSpeakers and trainersPreliminary programmePractical informationSponsorsMedia kit Overview Course overview The advent of serial crystallography at free electron laser sources and the following adaptation of these methods at 3rd and 4th generation synchrotrons have opened new possibilities to perform room temperature time resolved studies in macromolecular crystallography. This course aims to train the next generation of researchers ini) sample preparation: Participants will be trained and taught in the best practice to obtain homogenous microcrystals and in characterisation prior to loading using different sample delivery methods,ii) crystal delivery methods and data collection at a 4th generation synchrotron serial crystallography beamline: The new ID29 and similar endstations at other sources, presents experimental setup and data collection protocols that are unique in the...

EMBO Practical Course

EMBL Grenoble

Registration
Closed

8 July - 13 July 2024

Time-resolved STED nanoscopy in life sciences

8 July 20242024CourseEMBL Heidelberg

Marko Lampe, Andrea Mülter, Manuel Gunkel, Julia Roberti

OverviewSpeakersPreliminary ProgrammePractical informationSponsorsMedia kit Overview Course overview This six day comprehensive advanced microscopy course focuses on stimulated emission depletion microscopy STED and its application to biological questions Through lectures tutorials and practical workshops the course provides in depth knowledge on all aspects of STED Nanoscopy It... OverviewSpeakersPreliminary ProgrammePractical informationSponsorsMedia kit Overview Course overview This six-day comprehensive advanced microscopy course focuses on stimulated emission depletion microscopy (STED) and its application to biological questions. Through lectures, tutorials and practical workshops, the course provides in-depth knowledge on all aspects of STED Nanoscopy. It covers the fundamentals of STED microscopy, different technical implementations and has a strong emphasis on sample preparation – including choice of fluorophores and refractive index matching, as well as image acquisition strategies for fixed samples and living cells. Students will have the opportunity for exercises on state-of the art STED microscopes in which they will acquire high quality nanoscopy data. The faculty consists of invited guest researchers, experts from the EMBL and Leica Microsystems....

EMBL Course

EMBL Heidelberg

Registration
Closed

8 July - 9 July 2024

Hands-on Arthropod Bioinformatics Workshop

8 July 20242024CourseOther

Gloria I. Giraldo-Calderón

Join us for a 2 day workshop focused on hands on training on utilising web based data mining resources for arthropods Ensembl Metazoa and VectorBase to analyse both public and private datasets Omics data technologies allow scientists to analyse the genomes transcriptomes proteomes and genetic variability of arthropods These analyses enable the exploration of diverse research inquiries such as host pathogen interactions insecticide resistance diversity and many other aspects of behaviour biology and ecology In this workshop participants will learn to formulate testable hypotheses leveraging the power of these omics technologies To promote the accessibility and reuse of different data types numerous web based bioinformatics resources have been created Notably Ensembl and VectorBase stand out among a select group of essential resources for global research known as the Global Core Biodata Resources GCBRs and the Elixir Core Data Resources CDRs comprising only 31 and 37 members respectively As VectorBase is part of VEuPathDB insights gained can be extended to its other component sites encompassing parasites fungi and vertebrates Similarly within the Ensembl Genome project Ensembl Metazoa has the same type of tools and resources as Ensembl s sister sites... Join us for a 2-day workshop focused on hands-on training on utilising web-based data-mining resources for arthropods: Ensembl Metazoa and VectorBase, to analyse both public and private datasets. Omics data technologies allow scientists to analyse the genomes, transcriptomes, proteomes, and genetic variability of arthropods. These analyses enable the exploration of diverse research inquiries such as host-pathogen interactions, insecticide resistance, diversity, and many other aspects of behaviour, biology, and ecology. In this workshop participants will learn to formulate testable hypotheses, leveraging the power of these omics technologies. To promote the accessibility and reuse of different data types, numerous web-based bioinformatics resources have been created. Notably, Ensembl and VectorBase stand out among a select group of essential resources for...

Course

Other

Registration
Will open shortly

15 July - 19 July 2024

Proteomics bioinformatics

15 July 20242024CourseEMBL-EBI

Barbara Etzi

Thank you to those of you who have applied we have now selected our participants and wait list There are no more spaces available You can however register your interest for the 2025 course here This course provides hands on training in the basics of mass spectrometry MS and proteomics bioinformatics You will receive training on how to use search engines and post processing software quantitative approaches MS data repositories the use of public databases for protein analysis annotation of subsequent protein lists and incorporation of information from molecular interaction and pathway databases The practical elements of the course will take raw data from a proteomics experiment and analyse it You will be able to go from MS spectra to identifying and quantifying peptides and finally to obtaining lists of protein identifiers that can be analysed further using a wide range of resources The final aim is to provide you with the practical bioinformatics knowledge you need to go back to the lab and process your own data when collected This course is organised in association with the Vlaams Instituut voor Biotechnologie VIB the Flemish Institute for Biotechnology Pre recorded material may be provided before the course starts that you will need to watch read or work through to gain the most out of the actual training event In person courseThe course fee is inclusive of four nights of accommodation and catering including dinner We plan to deliver this course in person onsite at our training suite at EMBL EBI Hinxton Please be aware that we are continually evaluating the ongoing pandemic situation and as such may need to change the format of courses at short notice Your safety is paramount to us you can read our COVID guidance policy for more information All information is correct at time of publishing... Thank you to those of you who have applied, we have now selected our participants and wait list. There are no more spaces available. You can however register your interest for the 2025 course here. This course provides hands-on training in the basics of mass spectrometry (MS) and proteomics bioinformatics. You will receive training on how to use search engines and post-processing software, quantitative approaches, MS data repositories, the use of public databases for protein analysis, annotation of subsequent protein lists, and incorporation of information from molecular interaction and pathway databases.The practical elements of the course will take raw data from a proteomics experiment and analyse it. You will be able to go from MS spectra to identifying and quantifying peptides, and finally to obtaining lists of protein identifiers that can be analysed further using a wide range...

Course

EMBL-EBI

Registration
Closed

18 August - 26 August 2024

Advances in cryo-electron microscopy and 3D image processing

18 August 20242024CourseEMBL Heidelberg

Julia Mahamid, Sebastian Eustermann, Simone Mattei, Lori Passmore, Henning Stahlberg

This course provides the theoretical and practical foundations of advanced cryoEM techniques from sample preparation to data collection to image processing... OverviewSpeakersPreliminary programmePractical informationSponsorsMedia kit Overview Course overview Technology advances in cryo-electron microscopy (cryoEM) over the last decade have transformed our understanding of biomolecular structures across different spatial scales. CryoEM has unique capabilities for obtaining structural information in situ, within complex (cellular) environments, and to obtain atomic-level structures of biologically flexible and heterogeneous macromolecular assemblies. With the advent of the cryoEM ‘resolution revolution’, the method has undergone a tremendous growth in user base. Yet, emerging breakthroughs, such as new (correlated) imagine technologies and in AI-based image processing, demonstrate the potential for cryoEM to make another leap forward towards new frontiers. Therefore, in depth advanced training is essential to ensure future...

EMBO Practical Course

EMBL Heidelberg

Registration
26 May 2024

24 August - 27 August 2024

Transcription and chromatin

24 August 20242024ConferenceEMBL Heidelberg, Virtual

Shelley Berger, Eileen Furlong, Luca Giorgetti, Jürg Müller

The meeting brings together leading experts covering all aspects of transcription including cis regulatory function long range regulation 3 dimensional looping the basal transcriptional machinery RNA polymerase regulation and function nucleosome positioning chromatin modifications chromatin remodelling and epigenetic inheritance of transcriptional silencing... OverviewSpeakersPreliminary programmePractical informationSponsorsMedia kit Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Conference overview The EMBL ‘Transcription and chromatin’ conference has a long-standing tradition in shaping the field of transcriptional regulation. The meeting brings together leading experts covering all aspects of transcription including cis-regulatory function, long range regulation, 3-dimensional looping, the basal transcriptional machinery, RNA polymerase regulation and function, nucleosome positioning, chromatin modifications, chromatin remodelling, and epigenetic inheritance of transcriptional silencing. The meeting contains many talks selected from the abstracts that are interspersed with invited speakers, discussing the latest breakthroughs in transcriptional regulation. The conference is...

Conference

EMBL Heidelberg, Virtual

Registration (Virtual)
19 August 2024
Registration (On-site)
15 July 2024
Abstract submission
03 June 2024

1 September - 6 September 2024

Genome engineering: CRISPR/Cas in cells and mice

1 September 20242024CourseEMBL Heidelberg

Neil Humphreys, Kristof Kersse, Birgit Koch, Elisabeth Zielonka

OverviewSpeakersPreliminary programmePractical informationSponsorsMedia kit Overview Course overview This course will provide training in genome editing and cell engineering in mammalian cells and mouse embryos using the highly efficient CRISPR Cas9 system Participants will learn design of CRISPR targets using bioinformatics tools generation of gene knock outs knock ins and target... OverviewSpeakersPreliminary programmePractical informationSponsorsMedia kit Overview Course overview This course will provide training in genome editing and cell engineering in mammalian cells and mouse embryos using the highly efficient CRISPR/Cas9 system. Participants will learn design of CRISPR targets using bioinformatics tools, generation of gene knock-outs/knock-ins, and target validation using the most current technologies. The course will be split into two groups (mammalian cells OR mice) based on participants’ expertise. Please note that all participants are expected to engage in all sessions. Participants should plan for approximately 1 hour extra per day for self paced learning modules. Audience This course is aimed at researchers who are familiar with basic molecular and cell biology techniques and who want to learn how to create an engineered mammalian cell...

EMBL Course

EMBL Heidelberg

Registration
09 June 2024

1 September - 10 September 2024

Current methods in cell biology

1 September 20242024CourseEMBL Heidelberg

Niccolò Banterle, Beth Cimini, Simone Koehler

The course aims to expose researchers with different backgrounds to the diverse cutting edge methods developed for cell biology to showcase how integrated approaches can address the current big questions in cell biology... OverviewSpeakersPreliminary programmePractical informationSponsorsMedia kit Overview Course overview In the past decade, cell biology has undergone transformational changes resulting from improvements in single molecule imaging technologies and in-situ structural biology. At the same time, the emergence of deep learning approaches that have revolutionised the field of image analysis together with techniques that complement imaging approaches to e.g. dissect the mechanical properties of cells have provided a wealth of quantitative high-dimensional data for cell biologists. The wealth of data available to cell biologists also comes with new challenges in data handling, data analysis, and data interpretation. To allow researchers to design appropriate experiments and translate the data into meaningful knowledge requires insight into which techniques are best suited to address a specific...

Course

EMBL Heidelberg

Registration
09 June 2024

2 September - 5 September 2024

Imaging mouse development

2 September 20242024ConferenceEMBL Heidelberg, Virtual

Jan Ellenberg, Kate McDole, Isabel Espinosa Medina, Robert Prevedel, Shankar Srinivas

OverviewSpeakersPreliminary ProgrammePractical informationSponsorsMedia kit Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Conference overview This workshop aims to bring together and help establish an emerging community with the common goal of four dimensional reconstruction of mammalian development A number of long standing questions... OverviewSpeakersPreliminary ProgrammePractical informationSponsorsMedia kit Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Conference overview This workshop aims to bring together and help establish an emerging community with the common goal of four dimensional reconstruction of mammalian development. A number of long­standing questions surrounding the early development of mammals have been inaccessible to molecular research due to technical limitations and poor physical accessibility of these processes. How is the body plan established in the early embryo? How is morphogenesis coordinated with lineage specification? The recent revolutions in advanced light microscopy and bioimage informatics have opened up completely new avenues to address these questions and make fundamental advances in our understanding of the developing mammalian...

EMBO Workshop

EMBL Heidelberg, Virtual

Registration (Virtual)
26 August 2024
Registration (On-site)
22 July 2024
Abstract submission
10 June 2024

9 September - 16 September 2024

Membrane protein expression, purification, and characterisation 3 (mPEPC3)

9 September 20242024CourseEMBL Hamburg

Maria Garcia Alai, Simon Mortensen, Kim Remans, Henning Tidow

OverviewSpeakers and TrainersPreliminary pogrammePractical informationSponsorsMedia kit Overview Course overview This hands on course focuses on training participants on how to work with membrane proteins troubleshooting in the wet lab during solubilisation and reconstitution and conducting experiments at the beamlines and during early stages of cryoEM screening To perform integrated... OverviewSpeakers and TrainersPreliminary pogrammePractical informationSponsorsMedia kit Overview Course overview This hands-on course focuses on training participants on how to work with membrane proteins, troubleshooting in the wet lab during solubilisation and reconstitution, and conducting experiments at the beamlines and during early stages of cryoEM screening. To perform integrated structural biology experiments, well equipped crystallisation and cryo-EM facilities, as well as beamlines for SAXS for time-resolved macromolecular crystallography will be used. Audience Applicants in the early stage of their research careers (mid to end of PhD project or early postdoctoral career) will be given preference based on their application. We also welcome applications from non-academic labs. Modules Transient transfection of mammalian cells for recombinant Integral Membrane Proteins (IMP)...

Course

EMBL Hamburg

Registration
17 June 2024

9 September - 12 September 2024

Chemical biology 2024

9 September 20242024ConferenceEMBL Heidelberg, Virtual

Yimon Aye, Bryan Dickinson, Maja Köhn

OverviewSpeakersPreliminary programmePractical informationSponsorsMedia kit Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Conference overview The conference sets the stage for the dissemination and exchange of new developments in diverse emerging fields within chemical biology It is the largest and longest standing conference in the... OverviewSpeakersPreliminary programmePractical informationSponsorsMedia kit Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Conference overview The conference sets the stage for the dissemination and exchange of new developments in diverse, emerging fields within chemical biology. It is the largest and longest-standing conference in the field, being a platform for inspiration, collaboration, and networking for researchers in academia and industry. We aim to provide the possibility for every chemical biologist to meet and discuss with peers topics ranging from tool development to biological applications, from computational protein design to new drug modalities. Session topics Chemical biology meets drug discovery Chemical biology of posttranslational modifications Non-coding RNA and unusual RNA products Lipids and lipidation Chemical...

EMBO Workshop

EMBL Heidelberg, Virtual

Registration (Virtual)
02 September 2024
Registration (On-site)
29 July 2024
Abstract submission
10 June 2024

15 September - 22 September 2024

Synthetic biology in action: engineering synthetic systems

15 September 20242024CourseEMBL Heidelberg, Virtual

Sven Panke, Vitor Pinheiro, Karen Polizzi, Nico Claassens, Velia Siciliano

OverviewSpeakersPreliminary ProgrammePractical InformationSponsorsMedia kit Overview Course overview Synthetic Biology SynBio has become a rapidly developing area for tackling a large number of challenges in life science research This is due to a combination of foundational advances in technologies such as large scale DNA synthesis and new methods that allow integrating such raw... OverviewSpeakersPreliminary ProgrammePractical InformationSponsorsMedia kit Overview Course overview Synthetic Biology (SynBio) has become a rapidly developing area for tackling a large number of challenges in life science research. This is due to a combination of foundational advances in technologies, such as large-scale DNA synthesis and new methods that allow integrating such raw synthesis power into engineering approaches. Those include genome wide small RNA regulation, dCas9-based regulation, and multiplexed genome engineering. Such fresh approaches fuel new types of biotechnological applications with immense impact on both fundamental science and society. This course will be offered in both onsite and virtual format, with different modules available to each format. It will provide the best and most exciting novelties in the field and focus on exploiting tools and concepts of SynBio...

EMBO Practical Course

EMBL Heidelberg, Virtual

Registration
23 June 2024

17 September - 20 September 2024

Reconstructing the human past: using ancient and modern genomics

17 September 20242024ConferenceEMBL Heidelberg, Virtual

Johannes Krause, Ida Moltke, Maanasa Raghavan, Pontus Skoglund

Combining genome wide data from ancient and modern populations opens new windows into the past Population scale sequencing projects investigating past and present human diversity have already provided us with extraordinary insights into patterns of human variation and mobility through time and space This meeting will involve scientists from population genetics bioinformatics microbiology anthropology archaeology and history and will strengthen future interactions in this young research field that is already changing the way we think about our past and will shape how we study genetic variation in the future... OverviewSpeakersPreliminary programmePractical informationSponsorsAboutMedia kit Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Symposium overview Combining genome-wide data from ancient and modern populations opens new windows into the past and, importantly, their integration with archaeological evidence and historical records elucidates aspects of human history and cultural evolution of past societies. Population-scale sequencing projects investigating past and present human diversity have already provided us with extraordinary insights into patterns of human variation and mobility through time and space. Moreover, genome-wide data from archaic human remains, such as Neandertals and Denisovans, allows to investigate human evolution in action and to provide direct insights into genetic changes that define our own lineage. The available...

EMBO | EMBL Symposium

EMBL Heidelberg, Virtual

Registration (Virtual)
10 September 2024
Registration (On-site)
06 August 2024
Abstract submission
18 June 2024

23 September - 27 September 2024

Metagenomics bioinformatics at MGnify

23 September 20242024CourseVirtual

Meredith Willmott

Learn about the tools processes and analysis approaches used in the field of genome resolved metagenomics This course will cover the use of publicly available resources to manage share analyse and interpret metagenomics data focussing primarily on assembly based approaches The delivered content will involve participants learning via live lectures and presentations followed by live Q As with the trainers Practical experience will be developed in group activities and in computational exercises run using containerised tools on our training infrastructure... Learn about the tools, processes, and analysis approaches used in the field of genome-resolved metagenomics.This course will cover the use of publicly available resources to manage, share, analyse, and interpret metagenomics data, focussing primarily on assembly-based approaches.The delivered content will involve participants learning via live lectures and presentations, followed by live Q&As with the trainers. Practical experience will be developed in group activities and in computational exercises run using containerised tools on our training infrastructure.

Course

Virtual

Registration
09 June 2024

23 September - 27 September 2024

Single-cell RNA-seq analysis with Python

23 September 20242024CourseVirtual

Juanita Riveros

This course covers the analysis of single cell RNA seq data using Python and command line tools Participants will be guided through droplet based single cell RNA seq analysis pipelines from raw reads to cell clusters Furthermore you ll learn how to generate common plots for visualisation and analysis of gene expression data including TSNE UMAP and violin plots Please note that participants will not analyse their own data as part of the course There will however be ample opportunity to discuss their research and ideas with other course participants and trainers Virtual courseParticipants will learn via a mix of pre recorded lectures live presentations and trainer Q A sessions Practical experience will be developed through trainer led computational exercises and group activities Live sessions will be delivered using Zoom with additional support and asynchronous communication via Slack Pre recorded material may be provided before the course starts that participants will need to watch read or work through to gain the most out of the actual training event In the week before the course there will be a brief induction session Computational practicals will run on EMBL EBI s virtual training infrastructure meaning participants will not require access to a powerful computer or install complex software on their own machines Participants will need to be available between the hours of 09 00 17 30 BST each day of the course Trainers will be available to assist answer questions and provide further explanations during these times... This course covers the analysis of single cell RNA-seq data using Python and command line tools. Participants will be guided through droplet-based single cell RNA-seq analysis pipelines from raw reads to cell clusters. Furthermore, you'll learn how to generate common plots for visualisation and analysis of gene expression data, including TSNE, UMAP, and violin plots.Please note that participants will not analyse their own data as part of the course. There will, however, be ample opportunity to discuss their research and ideas with other course participants and trainers.Virtual courseParticipants will learn via a mix of pre-recorded lectures, live presentations, and trainer Q&A sessions. Practical experience will be developed through trainer-led computational exercises and group activities. Live sessions will be delivered using Zoom with additional support and asynchronous...

Course

Virtual

Registration
09 June 2024

30 September - 3 October 2024

Defining and defeating metastasis

30 September 20242024ConferenceEMBL Heidelberg, Virtual

Eduard Batlle, Johanna Joyce, Daniel Klimmeck, Joan Massagué, Samra Turajlic

This symposium will bring together researchers from diverse fields to enhance our understanding of the dissemination and metastatic colonisation of tumour cells It will provide a unique opportunity for interdisciplinary exchange on current approaches and future collaborations on metastasis and its therapeutic challenges... OverviewSpeakersPreliminary programmePractical informationSponsorsAboutMedia kit Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Symposium overview In its second edition, this symposium will cover emerging key concepts of latent metastasis and dissemination of tumour cells including evolution and genetic diversity of metastasis, circulating tumour cells, stemness, dormancy and stromal reprogramming, transcriptional and epigenetic control, motility and invasive signalling, metastatic heterogeneity, EMT and plasticity, immune evasion, and metabolic adaptations. The meeting will provide a unique interdisciplinary exchange on current approaches and future collaborations on metastasis and its therapeutic challenges. Metastasis research is a nexus for several of the most exciting areas and technical developments of current cancer biology and...

EMBO | EMBL Symposium

EMBL Heidelberg, Virtual

Registration (Virtual)
23 September 2024
Registration (On-site)
19 August 2024
Abstract submission
08 July 2024

8 October - 11 October 2024

Molecular mechanisms in evolution and ecology

8 October 20242024ConferenceEMBL Heidelberg, Virtual

Gilles Fischer, Jordi van Gestel, Kimberley Kline, Sara Mitri, Antonis Rokas

This conference series has become known for exploring yeasts as models to study questions of general relevance to evolution and ecology Experts will speak on a range of topics including evolution theory ecology genetics cell biology genomics systems biology metabolic modelling and engineering... OverviewSpeakersPreliminary programmePractical informationSponsorsMedia Kit Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Conference overview Dramatic advances in omics technologies and genetic engineering now enable us to tackle one of biology’s most fascinating problems – how evolution works in life’s communities and ecosystems. Gaining mechanistic insights requires bringing together multiple disciplines and viewpoints. The focus of this workshop series is on interspecies and cell-environment interactions across living organisms, with a special focus on bacteria, microbial eukaryotes, and viruses. The workshop series aims to highlight the latest technological advances, amplify scientific and societal focus on biodiversity, and showcase studies on the vital role of microbes in planetary ecosystems. The 2024 meeting will bring together...

Conference

EMBL Heidelberg, Virtual

Registration (Virtual)
01 October 2024
Registration (On-site)
27 August 2024
Abstract submission
10 July 2024

13 October - 18 October 2024

Metabolite and species dynamics in microbial communities

13 October 20242024CourseEMBL Heidelberg, Other

Sunil Laxman, Kiran Patil, Elisabeth Zielonka, Maria Zimmermann-Kogadeeva

The main goal of the course is to equip the participants with the state of the art concepts in microbial ecosystems and introduce them to the key tools towards gaining mechanistic insights in community dynamics... OverviewSpeakersPreliminary programmePractical informationSponsorsMedia kit Overview This is a two-hub course taking place in parallel at both EMBL Heidelberg, Germany and the Bangalore Life Science Cluster (BLiSC) Campus in Bangalore, India. Applicants can apply for either location and are encouraged to apply for the one that is closest to them. Course overview Metagenomics studies are rapidly uncovering the compositional richness of microbial communities in diverse habitats ranging from the oceans to the human gut. While their fundamental role in our health and environment is undeniable, there is an urgent need for unravelling molecular mechanisms underlying the dynamics of these communities. This requires a combined experimental and computational approach. Recent studies (including those from the organisers’ and speakers’ labs) have underlined the success of such integrative...

EMBO Practical Course

EMBL Heidelberg, Other

Registration
22 July 2024

15 October - 18 October 2024

The complex life of RNA

15 October 20242024ConferenceEMBL Heidelberg, Virtual

Elena Conti, Olivier Duss, Torben Heick Jensen, Karla Neugebauer

This symposium brings together leaders in the RNA field post docs and students with the aim of disseminating and discussing the most recent findings of information added to mRNAs The programme will include among others sessions on transcription RNA processing and modification mRNA export and localisation mRNA surveillance and decay translation and the control of mRNA expression by microRNAs... OverviewSpeakersProgrammePractical informationSponsorsAboutMedia kit Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Symposium overview Before the genetic information stored in DNA can be used to direct cell growth and metabolism, it has to be transferred into RNA. Messenger RNAs (mRNAs) that code for proteins and noncoding RNAs are key components in the transmission of genetic information in all life forms – from viruses to complex mammalian organisms. Following the great success of the 2022 edition of this long-standing symposium, we are looking forward to returning in 2024, bringing together leaders in the RNA field, post-docs and students, with the aim of disseminating and discussing the most recent results. The programme will include topics on transcription, RNA processing and modification, mRNA export and localisation, mRNA...

EMBO | EMBL Symposium

EMBL Heidelberg, Virtual

Registration (Virtual)
08 October 2024
Registration (On-site)
03 September 2024
Abstract submission
23 July 2024

21 October - 26 October 2024

Imaging down to single-molecule resolution: STED & MINFLUX nanoscopy

21 October 20242024CourseEMBL Heidelberg

Clara Gürth, Charlotte Kaplan, Marko Lampe, Ulf Matti, Julia Menzel, Sebastian Schnorrenberg

OverviewSpeakers trainers and staffPreliminary programmePractical informationSponsorsMedia kit Overview Course overview The aim of the course is to train microscopy users in different super resolution microscopy methods Stimulated Emission Depletion STED and MINFLUX nanoscopy Both techniques overcome the diffraction limit of light with the help of a donut shaped laser beam... OverviewSpeakers, trainers, and staffPreliminary programmePractical informationSponsorsMedia kit Overview Course overview The aim of the course is to train microscopy users in different super-resolution microscopy methods: Stimulated Emission Depletion (STED) and MINFLUX nanoscopy. Both techniques overcome the diffraction limit of light with the help of a donut-shaped laser beam, thereby achieving resolutions that are impossible with conventional light microscopy.The course combines scientific lectures by experienced researchers from the super-resolution field with hands-on sessions at the different super-resolution microscopes and in the laboratory. Participants will gain a technical understanding of the methods as well as an overview of different application fields and imaging techniques, sample preparation, and data handling for both STED and MINFLUX. After the course, participants...

Course

EMBL Heidelberg

Registration
29 July 2024

29 October - 31 October 2024

Managing a bioinformatics core facility

29 October 20242024CourseEMBL-EBI

Barbara Etzi

This knowledge exchange workshop is an opportunity for managers of bioinformatics core facilities to learn from EMBL EBI s service teams and from each other These facilities play an essential role in enabling research in the life sciences The landscape is constantly evolving as new research tools emerge as experiments become increasingly data intensive and as their users experimental researchers become more exposed to the power of data driven biology This course will allow participants to share experiences discuss challenges and solutions that they face and plan ways to cope with the ever changing demands raised by the molecular life science field It will include sessions to learn from bioinformatics service providers hear how others have tackled common problems and work together to design core services resource them and measure their impact A limited number or travel bursaries are available Please see the Additional information tab for conditions... This knowledge exchange workshop is an opportunity for managers of bioinformatics core facilities to learn from EMBL-EBI’s service teams, and from each other. These facilities play an essential role in enabling research in the life sciences. The landscape is constantly evolving as new research tools emerge, as experiments become increasingly data intensive, and as their users – experimental researchers – become more exposed to the power of data-driven biology.This course will allow participants to share experiences, discuss challenges and solutions that they face, and plan ways to cope with the ever changing demands raised by the molecular life science field. It will include sessions to learn from bioinformatics service providers, hear how others have tackled common problems, and work together to design core services, resource them, and measure their impact.A limited number or travel...

Course

EMBL-EBI

Registration
28 July 2024

4 November - 8 November 2024

The fundamentals of high-end cell sorting

4 November 20242024CourseEMBL Heidelberg

Beata Ramasz, Diana Ordonez

OverviewSpeakersPreliminary programmePractical informationSponsorsMedia kit Overview Course overview This course includes a robust theoretical part on the fundamentals of cell sorting delivered by world leading experts and practical sessions on using standard cuvette sorters In addition the course program will include principles applications and hands on sessions on Image Cell Sorting ICS... OverviewSpeakersPreliminary programmePractical informationSponsorsMedia kit Overview Course overview This course includes a robust theoretical part on the fundamentals of cell sorting delivered by world-leading experts and practical sessions on using standard cuvette sorters. In addition, the course program will include principles, applications, and hands-on sessions on Image Cell Sorting (ICS), allowing attendees to get in touch with this exciting technology! Audience The course is intended for Ph.D. students and postdocs who are starting to use or already using cell sorting in their research projects. Applicants with previous active knowledge of basic principles of flow cytometry and regular use of flow cytometers in daily research will profit most from the course content. Modules/Resources The topics that will be covered include; instrument set-up and validation, correct operation to...

EMBO Practical Course

EMBL Heidelberg

Registration
05 August 2024

4 November - 8 November 2024

Structural bioinformatics

4 November 20242024CourseVirtual

Juanita Riveros

This course provides a guide to the commonly used methods and tools in structural bioinformatics to analyse and interpret experimentally determined and AI predicted macromolecular structure data Structural biology determining the three dimensional shapes of biomacromolecules and their complexes can tell us a lot about how these molecules function and the roles they play within a cell Data derived from structure determination experiments and Artificial Intelligence AI assisted structure prediction enables life science researchers to address a wide variety of questions This course explores bioinformatics data resources and tools for the investigation analysis and interpretation of both experimentally determined and predicted biomacromolecular structures It will focus on how best to analyse and interpret available structural data to gain useful information given specific research contexts The course content will also cover predicting function and exploring interactions with other macromolecules Successful participants may be sent materials prior to the course These might include pre recorded talks and required reading or online training that will be essential to fully engage with the course... This course provides  a guide to the commonly used methods and tools in structural bioinformatics to analyse and interpret experimentally determined and AI-predicted macromolecular structure data.Structural biology, determining the three-dimensional shapes of biomacromolecules and their complexes, can tell us a lot about how these molecules function and the roles they play within a cell. Data derived from structure determination experiments and Artificial Intelligence (AI)-assisted structure prediction enables life-science researchers to address a wide variety of questions.  This course explores bioinformatics data resources and tools for the investigation, analysis, and interpretation of both experimentally determined and predicted biomacromolecular structures. It will focus on how best to analyse and interpret available structural data to gain useful information...

Course

Virtual

Registration
28 July 2024

5 November - 8 November 2024

DNA replication: from basic biology to disease

5 November 20242024ConferenceEMBL Heidelberg, Virtual

Anja Groth, Thanos Halazonetis, Helle Ulrich

OverviewSpeakersProgrammePractical informationSponsorsAboutMedia Kit Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Symposium overview There has been tremendous progress in the past few years regarding our understanding of DNA replication in eukaryotes both yeast and mammals Many important questions in the field are poised to be answered... OverviewSpeakersProgrammePractical informationSponsorsAboutMedia Kit Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Symposium overview There has been tremendous progress in the past few years regarding our understanding of DNA replication in eukaryotes, both yeast and mammals. Many important questions in the field are poised to be answered within the next decade. These include understanding DNA replication at the biochemical and three-dimensional protein structure levels. In addition, studies using high throughput technologies at the cellular and organismal levels are poised to answer how accurate replication of the genome is ensured by controlling origin firing in space and time. Session topics Replisome structure Origin selection, licensing and firing Chromatin replication Replication stress and fork stability Replication in cancer...

EMBO | EMBL Symposium

EMBL Heidelberg, Virtual

Registration (Virtual)
08 October 2024
Registration (On-site)
24 September 2024
Abstract submission
13 August 2024

14 November - 15 November 2024

The next generation in infection biology

14 November 20242024ConferenceVirtual

Maria Bernabeu, Jan Kosinski, Eva Kowalinski, John Lees, Lizette de Paula, Nassos Typas

Infectious diseases are among the most prevalent causes of human illness and death in the world Pathogens infect humans and all life forms on Earth being able to cross species barriers thereby adversely impacting human and planetary health Fundamental research in Infection Biology is urgently needed to find therapies for longstanding and emerging infectious diseases... OverviewOrganisers and SpeakersPractical informationSponsorsMedia kit Overview Registration is not yet open for this event. If you are interested in receiving more information please register your interest. After the success of the virtual 2022 edition, this conference will return in a virtual format. Conference overview Infectious diseases are among the most prevalent causes of human illness and death in the world. Pathogens infect humans and all life forms on Earth, being able to cross species barriers, thereby adversely impacting human and planetary health. Fundamental research in infection biology is urgently needed to find therapies for longstanding and emerging infectious diseases.   The EMBL Conference ‘The next generation in infection biology’ is a platform for late-stage postdoctoral scientists in the field of infection biology to present their work and...

EMBL Conference

Virtual

Registration
Will open shortly

17 November - 24 November 2024

Integrative structural biology: solving molecular puzzles

17 November 20242024CourseEMBL Hamburg

Arjen Jakobi, Jan Kosinski, Maya Topf

This practical course offers a hands on introduction to integrative structural biology Participants will delve into the fundamentals of various experimental structure determination techniques including X ray crystallography cryo EM small angle X ray scattering NMR and mass spectrometry through both lectures and practical exercises... OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview Course overview Integrative structural biology has become a key strategy for determining the structure of biological macromolecules and their complexes. This method entails characterising the 3D structure through an array of complementary techniques, subsequently combining the data to form a consensus model using computational methodologies. This practical course offers a hands-on introduction to integrative structural biology. Participants will delve into the fundamentals of various experimental structure determination techniques including X-ray crystallography, cryo-EM, small-angle X-ray scattering, NMR, and mass spectrometry, through both lectures and practical exercises. Experts in the field will guide participants on how to analyse and interpret experimental data, and construct structural models across...

Course

EMBL Hamburg

Registration
25 August 2024

17 November - 22 November 2024

Humanized mice: immunotherapy and regenerative medicine

17 November 20242024CourseEMBL Heidelberg

Christian Münz, Jan Jacob Schuringa, Leonard Shultz, Brian Soper, Renata Stripecke, Anja Wege

OverviewSpeakersPreliminary programmePractical informationSponsorsMedia kit Overview Course overview Humanized mouse models became an integral part of basic and translational biomedical research for the understanding of human pathologies and for development of new therapies Human cells or tissues implanted in mice can reflect human hematopoiesis immunity oncology infections physiology... OverviewSpeakersPreliminary programmePractical informationSponsorsMedia kit Overview Course overview Humanized mouse models became an integral part of basic and translational biomedical research for the understanding of human pathologies and for development of new therapies. Human cells or tissues implanted in mice can reflect human hematopoiesis, immunity, oncology, infections, physiology and genetic polymorphisms. The development of immunotherapeutic drugs, cell and tissue therapies rely on the preclinical testing to assess their potency and safety. “Big pharma” and biotech companies include humanized mice in the non-clinical development portfolio. Humanized mouse models have varied among laboratories regarding the use of new transgenic and knock-out strains, improved handling methods, innovative sources and manipulation techniques of the human graft material and novel technological...

EMBO Practical Course

EMBL Heidelberg

Registration
25 August 2024

18 November - 22 November 2024

Genome bioinformatics: from short- to long-read sequencing

18 November 20242024CourseEMBL-EBI

Meredith Willmott

A guide to the technology analysis workflows tools and resources for next generation sequencing data analysis This course will provide insights and training into how biological knowledge can be derived from genomics experiments and explain different approaches in analysing such data The main focus will be on introducing sequence informatics re sequencing differences between short and long read sequencing and variant calling during the analysis of higher eukaryotes with an emphasis on human genetic research Throughout the week more advanced topics will introduce the creation of pipelines automation and the scaling up of analysis experiments Practical sessions will be run on datasets prepared by the trainers not on personal research data Participants will learn how to process these training datasets and to apply appropriate statistical methods in their analyses This course is currently under development please check back again soon for further details... A guide to the technology, analysis workflows, tools, and resources for next-generation sequencing data analysis. This course will provide insights and training into how biological knowledge can be derived from genomics experiments and explain different approaches in analysing such data. The main focus will be on introducing sequence informatics, re-sequencing, differences between short- and long-read sequencing, and variant calling during the analysis of higher-eukaryotes, with an emphasis on human genetic research. Throughout the week, more advanced topics will introduce the creation of pipelines, automation, and the scaling-up of analysis experiments. Practical sessions will be run on datasets prepared by the trainers, not on personal research data. Participants will learn how to process these training datasets and to apply appropriate statistical methods in their analyses....

Course

EMBL-EBI

Registration
22 July 2024

18 November - 22 November 2024

Plant genomes: from data to discovery

18 November 20242024CourseVirtual

Barbara Etzi

This course will take you through a selection of genomic tools and open resources to help you explore plant genomes and answer biological questions Covering a range of omics data including genomic proteomic and imaging data this course will show you where to find relevant data and how to use publicly available tools to connect across resources supporting plant genomic data driven knowledge discovery Virtual courseParticipants will learn via a mix of pre recorded lectures live presentations and trainer Q A sessions Practical experience will be developed through trainer led computational exercises Live sessions will be delivered using Zoom with additional support and asynchronous communication via Slack Computational practicals will run using online tools meaning participants will not require access to a powerful computer or install complex software on their own machines In the week before the course there will be a brief induction session Participants will need to be available between the hours of 09 00 17 00 GMT each day of the course Trainers will be available to assist answer questions and provide further explanations during these times... This course will take you through a selection of genomic tools and open resources to help you explore plant genomes and answer biological questions. Covering a range of omics data including genomic, proteomic, and imaging data, this course will show you where to find relevant data and how to use publicly available tools to connect across resources supporting plant genomic data-driven knowledge discovery.Virtual courseParticipants will learn via a mix of pre-recorded lectures, live presentations, and trainer Q&A sessions. Practical experience will be developed through trainer-led computational exercises. Live sessions will be delivered using Zoom with additional support and asynchronous communication via Slack.Computational practicals will run using online tools, meaning participants will not require access to a powerful computer or install complex software on their own machines. In...

Course

Virtual

Registration
01 September 2024

19 November - 22 November 2024

Quantitative biology to molecular mechanisms

19 November 20242024ConferenceEMBL Heidelberg, Virtual

Lacramioara Bintu, Hartland Jackson, Arnaud Krebs, Tineke Lenstra, Mikhail Savitski

OverviewSpeakersPreliminary programmePractical informationSponsorsMedia kit Overview This conference will take place at EMBL Heidelberg with the option to attend virtually and is being organised by EMBL with generous support from the Bayer Foundation Conference overview Recent decades have witnessed a profound transformation in molecular biology research fueled by revolutionary... OverviewSpeakersPreliminary programmePractical informationSponsorsMedia kit Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually and is being organised by EMBL with generous support from the Bayer Foundation Conference overview Recent decades have witnessed a profound transformation in molecular biology research, fueled by revolutionary technologies that have greatly enhanced our ability to systematically and quantitatively measure biological molecules. The use of genomics, proteomics, and imaging have become routine, generating vast amounts of high-resolution data that characterise biological systems across multiple scales, ranging from molecules to organisms. This technological leap allows us to describe biological systems in quantitative terms with unprecedented resolution and provides a solid foundation for formulating mechanistic models...

Conference

EMBL Heidelberg, Virtual

Registration (Virtual)
12 November 2024
Registration (On-site)
08 October 2024
Abstract submission
27 August 2024

3 December - 6 December 2024

Hands-on course for sample preparation and data analysis in proteomics

3 December 20242024CourseEMBL Heidelberg

Mandy Rettel, Mikhail Savitski, Frank Stein

OverviewSpeakersPreliminary programmePractical informationSponsorsMedia kit Overview Course overview The course will give an introduction to the theoretical aspects of the analysis of proteins peptides by mass spectrometry Participants will get hands on experience in sample preparation for a quantitative comparison across samples and perform a state of the art sample preparation and tandem... OverviewSpeakersPreliminary programmePractical informationSponsorsMedia kit Overview Course overview The course will give an introduction to the theoretical aspects of the analysis of proteins/peptides by mass spectrometry. Participants will get hands-on experience in sample preparation for a quantitative comparison across samples and perform a state of the art sample preparation and tandem mass tag labelling. Samples prepared by the participants will be measured by liquid chromatography-tandem mass spectrometry. In a session focused on bioinformatics analysis, participants will use FragPipe and FragPipe-Analyst in order to process the acquired data. Audience The course is intended for scientists that use or want to use proteomics for their research. Applicants should have an understanding of protein biology and should know the principle of proteomics. Ideally, they have some prior...

EMBL Course

EMBL Heidelberg

Registration
03 September 2024

27 January - 31 January 2025

Computing skills for reproducible research: data carpentry or software carpentry

27 January 20252025CourseEMBL Heidelberg

Renato Alves, Lisanna Paladin

OverviewSponsors Overview Registration is not yet open for this event If you are interested in receiving more information please register your interest Course overview The missing step between data collection and research progress is a lack of training for researchers in crucial skills for effectively managing and analysing data often in large amounts This hands on workshop teaches... OverviewSponsors Overview Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Course overview The missing step between data collection and research progress is a lack of training for researchers in crucial skills for effectively managing and analysing data, often in large amounts. This hands-on workshop teaches researchers the fundamental data skills they need to conduct their work and provides high-quality, domain-specific training covering the full lifecycle of data-driven research. The domain-specific approach allows participants to tailor the data, content, and tools to reflect the specific data and analysis needs of different areas. Audience The course is aimed at graduate students and other researchers in the life sciences who would like to learn good practices in project and data organisation and...

Course

EMBL Heidelberg

Registration
Will open shortly

4 February - 7 February 2025

In-situ structural biology: expanding the toolbox for structural cell biology

4 February 20252025ConferenceEMBL Heidelberg, Virtual

Julia Mahamid, Jonas Ries, Stefano Vanni

This conference will bring together experts and early stage researchers from the separate fields to define what types of biological questions can already be addressed using in situ structural biology and which might be approached in the future... OverviewSponsors Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Event details to be confirmed, pending EMBO funding application Conference overview There is an increasing awareness that mechanistic structural information on molecular machines is ideally generated within the context of intact cells to fully grasp how they function in a complex native environment. Recent technological advances have nurtured the development of such in situ structural biology approaches in several disciplines, including cryo-EM, mass spectrometry, super-resolution microscopy, NMR, computational modelling, and others. This conference will bring together experts and early-stage researchers from separate fields to provide a...

EMBO Workshop

EMBL Heidelberg, Virtual

Registration
Will open shortly

9 February - 14 February 2025

In situ CLEM at room temperature and in cryo

9 February 20252025CourseEMBL Heidelberg

Ori Avinoam, Mandy Bormel, Rachel Mellwig, Martin Schorb

During this course we will focus on a specific method that has been developed at EMBL that enables the localisation of fluorescent proteins with high accuracy at the ultrastructural level The course will cover both the theory and practicals of high precision CLEM as well as opportunities to discuss their research with CLEM experts and receive practical and troubleshooting advice... OverviewSponsors Overview Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Course overview Correlative Light and Electron Microscopy (CLEM) allows precise localisation of an event of interest within cells and tissues. During this course, we will focus on a specific method that has been developed at EMBL that enables the localisation of fluorescent proteins with high accuracy at the ultrastructural level. The course will cover both the theory and practicals of high precision CLEM, as well as opportunities to discuss their research with CLEM experts and receive practical and troubleshooting advice. Audience This course is intended for scientists with experience in EM who want to further develop their skills in high-accuracy correlated microscopy. Modules/resources The course will combine lectures and...

EMBO Practical Course

EMBL Heidelberg

Registration
Will open shortly

17 February - 21 February 2025

Single-cell RNA-seq analysis with Python

17 February 20252025CourseVirtual

EMBL-EBI Training

This course covers the analysis of single cell RNA sequencing scRNA seq data using Python and command line tools Participants will be guided through droplet based scRNA seq analysis pipelines from raw reads to cell clusters You will explore and interpret single cell RNA seq data using Python as well as the Single Cell Expression Atlas Finally you will put their knowledge into practice through a group challenge on the last day Please note that you will not analyse your own data as part of the course There will however be ample opportunity to discuss your research and ideas with other course participants and trainers Virtual courseParticipants will learn via a mix of pre recorded lectures live presentations and trainer Q A sessions Practical experience will be developed through group activities and trainer led computational exercises Live sessions will be delivered using Zoom with additional support and asynchronous communication via Slack Pre recorded material may be provided before the course starts that participants will need to watch read or work through to gain the most out of the actual training event In the week before the course there will be a brief induction session Computational practicals will run on EMBL EBI s virtual training infrastructure meaning you will not require access to a powerful computer or install complex software on your own machines Participants will need to be available between the hours of 09 00 17 30 BST each day of the course Trainers will be available to assist answer questions and provide further explanations during these times This course is currently under construction and so details are subject to change Please note that we will operate this course virtually Hybrid options are not currently available We reserve the right to change the format of this course or cancel it... This course covers the analysis of single cell RNA sequencing (scRNA-seq) data using Python and command line tools. Participants will be guided through droplet-based scRNA-seq analysis pipelines from raw reads to cell clusters. You will explore and interpret single-cell RNA seq data using Python as well as the Single Cell Expression Atlas. Finally, you will put their knowledge into practice through a group challenge on the last day.Please note that you will not analyse your own data as part of the course. There will, however, be ample opportunity to discuss your research and ideas with other course participants and trainers.Virtual courseParticipants will learn via a mix of pre-recorded lectures, live presentations, and trainer Q&A sessions. Practical experience will be developed through group activities and trainer-led computational exercises. Live sessions will be delivered using...

Course

Virtual

Registration
17 November 2024

17 February - 21 February 2025

Deep learning for image analysis

17 February 20252025CourseEMBL Heidelberg

OverviewSponsors Overview Registration is not yet open for this event If you are interested in receiving more information please register your interest Course overview The advent of deep learning has brought a revolution in the field of computer vision including most tasks and research questions concerned with microscopy image analysis Neural networks have been successfully used for... OverviewSponsors Overview Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Course overview The advent of deep learning has brought a revolution in the field of computer vision, including most tasks and research questions concerned with microscopy image analysis. Neural networks have been successfully used for image restoration, classification and segmentation, for the detection of objects and characterisation of their morphology, for high-throughput imaging and large-scale processing in 3D. Despite these advances, training and deployment of such neural networks remains difficult for practitioners of image analysis. The aim of our course is to close this gap and teach the participants – in the most hands-on way possible – to apply deep learning-based methods to their own data and image analysis problems....

Course

EMBL Heidelberg

Registration
Will open shortly

24 February - 28 February 2025

Introduction to RNA-seq and functional interpretation

24 February 20252025CourseVirtual

EMBL-EBI Training

Gain an introduction to the technology data analysis tools and resources used in RNA sequencing and transcriptomics The content will provide a broad overview of the subject area and introduce participants to basic analysis of transcriptomics data using the command line It will also highlight key public data repositories and methodologies that can be used to start the biological interpretation of expression data Topics will be delivered using a mixture of lectures practical exercises and open discussions Computational work during the course will use small example data sets and there will be no opportunity to analyse personal data Virtual courseParticipants will learn via a mix of pre recorded lectures live presentations and trainer Q A sessions Practical experience will be developed through group activities and trainer led computational exercises Live sessions will be delivered using Zoom with additional support and asynchronous communication via Slack Pre recorded material may be provided before the course starts that participants will need to watch read or work through to gain the most out of the actual training event In the week before the course there will be a brief induction session Computational practicals will run on EMBL EBI s virtual training infrastructure meaning participants will not require access to a powerful computer or install complex software on their own machines Participants will need to be available between the hours of 09 00 16 00 hrs GMT each day of the course Trainers will be available to assist answer questions and provide further explanations during these times... Gain an introduction to the technology, data analysis, tools, and resources used in RNA sequencing and transcriptomics. The content will provide a broad overview of the subject area, and introduce participants to basic analysis of transcriptomics data using the command line. It will also highlight key public data repositories and methodologies that can be used to start the biological interpretation of expression data. Topics will be delivered using a mixture of lectures, practical exercises, and open discussions. Computational work during the course will use small, example data-sets; and there will be no opportunity to analyse personal data. Virtual courseParticipants will learn via a mix of pre-recorded lectures, live presentations, and trainer Q&A sessions. Practical experience will be developed through group activities and trainer-led computational exercises. Live sessions...

Course

Virtual

Registration
Will open shortly

3 March - 7 March 2025

Introduction to multi-omics data integration and visualisation

3 March 20252025CourseEMBL-EBI

EMBL-EBI Training

With the increase in the volume of data across the whole spectrum of biology more opportunities as well as challenges have been created to identify novel perspectives and answer questions in life sciences This may also include public domain data which can provide added value to data derived through the researcher s own work and inform experimental design The introductory course will highlight the challenges that researchers face in integrating multi omics data sets using biological examples The course will focus on the use of public data resources and open access tools for enabling integrated working with an emphasis on data visualisation This course will not include systems biology modelling or machine learning A major element of this course is a group project where participants will be placed in small groups to work together on a challenge set by trainers from EMBL EBI data resource and research teams This allows people to explore the bioinformatics tools and resources introduced in the course and to apply these to a set problem providing hands on experience of relevance to their own research The group work will culminate in a presentation session involving all participants on the final day of the course allowing wider discussion on the benefits and challenges of integrating data... With the increase in the volume of data across the whole spectrum of biology, more opportunities, as well as challenges, have been created to identify novel perspectives and answer questions in life sciences. This may also include public domain data, which can provide added value to data derived through the researcher’s own work and inform experimental design. The introductory course will highlight the challenges that researchers face in integrating multi-omics data sets using biological examples. The course will focus on the use of public data resources and open access tools for enabling integrated working, with an emphasis on data visualisation. This course will not include systems biology modelling or machine learning.A major element of this course is a group project, where participants will be placed in small groups to work together on a challenge set by trainers from EMBL-EBI...

Course

EMBL-EBI

Registration
17 November 2024

9 March - 14 March 2025

Quantitative proteomics: Strategies and tools to probe biology

9 March 20252025CourseEMBL Heidelberg

Jeroen Krijgsveld, Christina Ludwig, Mikhail Savitski

OverviewSponsors Overview Registration is not yet open for this event If you are interested in receiving more information please register your interest Course overview Proteomic technologies continue to develop at a rapid pace offering the potential to address imminent questions in a range of biological research areas Mass spectrometry has become widely accessible to many biologists... OverviewSponsors Overview Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Course overview Proteomic technologies continue to develop at a rapid pace, offering the potential to address imminent questions in a range of biological research areas. Mass spectrometry has become widely accessible to many biologists, either through core facilities or scientific collaborations. Because quantitative proteomics includes a variety of specialised technologies and workflows each with specific advantages and limitations, this hands-on practical course aims to train biologists how best integrate these evolving proteomics technologies into their own research. To achieve this, expert tutors shall offer hands-on training in the analysis, interpretation, and statistical evaluation of various types of proteomic data through...

EMBO Practical Course

EMBL Heidelberg

Registration
Will open shortly

11 March - 14 March 2025

The expanding world of RBPs: from posttranscriptional control to riboregulation

11 March 20252025ConferenceEMBL Heidelberg, Virtual

Francesca Cuttruzola, Imed Gallouzi, Matthias Hentze, Narry Kim

OverviewSponsors Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Registration is not yet open for this event If you are interested in receiving more information please register your interest Conference overview Based on recent methodological breakthroughs the number of identified mammalian RNA binding proteins RBPs has skyrocketed... OverviewSponsors Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Conference overview Based on recent methodological breakthroughs, the number of identified mammalian RNA-binding proteins (RBPs) has skyrocketed from around 700 to over 2000. More importantly, completely new classes of proteins (including enzymes, signaling molecules, transporters and channels etc) were recognized as RBPs, posing questions regarding the biological functions of RNA binding. This workshop will bring together leaders in the field of RBPs – classical and newly discovered – and discuss exciting progress on all fronts, from posttranscriptional regulation of RNA expression to the riboregulation of protein functions, facilitated by rapidly...

EMBL Conference

EMBL Heidelberg, Virtual

Registration
Will open shortly

17 March - 21 March 2025

Gene-environment interactions in human health and disease

17 March 20252025CourseEMBL-EBI

EMBL-EBI Training

This introductory course explores the complex interplay between genes and the environment in shaping human phenotypes Participants will gain knowledge of cohort datasets environmental readouts and computational resources to investigate gene environment interactions Ethical and legal frameworks related to data privacy consent and genetic discrimination will be discussed The course also covers computational modelling techniques for integrating genotype and environmental effects By the end attendees will be equipped to analyse cohort datasets make use of computational resources and interpret the results Please note that you will not analyse your own data as part of the course There will however be ample opportunity to discuss your research and ideas with other course participants and trainers... This introductory course explores the complex interplay between genes and the environment in shaping human phenotypes. Participants will gain knowledge of cohort datasets, environmental readouts, and computational resources to investigate gene-environment interactions. Ethical and legal frameworks related to data privacy, consent, and genetic discrimination will be discussed. The course also covers computational modelling techniques for integrating genotype and environmental effects. By the end, attendees will be equipped to analyse cohort datasets, make use of computational resources, and interpret the results. Please note that you will not analyse your own data as part of the course. There will, however, be ample opportunity to discuss your research and ideas with other course participants and trainers

Course

EMBL-EBI

Registration
05 January 2025

18 March - 21 March 2025

Mechanisms of drug resistance and tolerance in bacteria, fungi and cancer

18 March 20252025ConferenceEMBL Heidelberg, Virtual

Judith Berman, Markus Ralser, Luiz Carvalho, Marina Rodnina

OverviewSpeakersSponsorsAboutMedia kit Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Registration is not yet open for this event If you are interested in receiving more information please register your interest Symposium overview Resilience to antimicrobial drugs is a rapidly increasing problem of global health Similarly cancer... OverviewSpeakersSponsorsAboutMedia kit Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Symposium overview Resilience to antimicrobial drugs is a rapidly increasing problem of global health. Similarly, cancer cells that become drug-resistant or tolerant affect therapy outcomes, for instance during cancer chemotherapy. The underlying biological mechanisms of tolerance, resistance, and persistence are increasingly being studied and reveal a complex interplay between (cellular) evolution, biochemistry, and metabolism. Understanding these mechanisms holds the long-term promise of developing new therapeutic strategies less prone to drug resistance and, in the short term, enhances our understanding of clonal evolution...

EMBO | EMBL Symposium

EMBL Heidelberg, Virtual

Registration
Will open shortly

31 March - 4 April 2025

Microscopy data analysis: machine learning and the BioImage Archive

31 March 20252025CourseVirtual

EMBL-EBI Training

This virtual course will show how public bioimaging data resources centred around the BioImage Archive enable and enhance machine learning based image analysis The content will explore a variety of data types including electron and light microscopy and miscellaneous or multi modal imaging data at the cell and tissue scale Participants will cover contemporary biological image analysis with an emphasis on machine learning methods as well as how to access and use images from databases Further instruction will be offered using applications such as ZeroCostDL4Mic ilastik the BioImage Model Zoo and CellProfiler Virtual course This course will be a virtual event delivered via a mixture of live streamed sessions pre recorded lectures and tutorials with live support We will be using Zoom to run the live sessions all fully password protected with automated English closed captioning and transcription with support and both scientific and social networking opportunities provided by Slack and other methods taking different time zones into account In order to make the most out of the course you should make sure to have a stable internet connection throughout the week and are available between 08 00 18 00 BST each day In the week before the course there will be a brief induction session Computational practicals will run on EMBL EBI s virtual training infrastructure meaning participants will not require access to a powerful computer or install complex software on their own machines Selected participants may be sent materials prior to the course These might include pre recorded talks and required reading or online training that will be essential to fully engage with the course... This virtual course will show how public bioimaging data resources, centred around the BioImage Archive, enable and enhance machine learning based image analysis. The content will explore a variety of data types including electron and light microscopy and miscellaneous or multi-modal imaging data at the cell and tissue scale. Participants will cover contemporary biological image analysis with an emphasis on machine learning methods, as well as how to access and use images from databases. Further instruction will be offered using applications such as ZeroCostDL4Mic, ilastik, the BioImage Model Zoo, and CellProfiler. Virtual course This course will be a virtual event delivered via a mixture of live-streamed sessions, pre-recorded lectures, and tutorials with live support. We will be using Zoom to run the live sessions (all fully password protected with automated English closed captioning...

Course

Virtual

Registration
05 January 2025

8 April - 11 April 2025

Wild frontiers of model organisms

8 April 20252025ConferenceEMBL Heidelberg, Virtual

Gautam Dey, Michael Dorrity, Nicole Dubilier, Susana Coelho, Flora Vincent

OverviewSpeakersSponsorsAbout Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Registration is not yet open for this event If you are interested in receiving more information please register your interest Symposium overview The scientific community has long relied on a small number of model organisms to study larger themes in biology... OverviewSpeakersSponsorsAbout Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Symposium overview The scientific community has long relied on a small number of model organisms to study larger themes in biology, with the assumption that gained insights can be extrapolated to most other organisms. However, recent advances in our ability to study organisms in the context of their natural environments have revealed that Jacques Monod’s famous quote, ‘What is true for E. coli is true for the elephant’ does not do justice to the vast diversity of life on our planet. This conference will showcase how a combination of lab- and field-based approaches applied to model and non-model organisms is increasing our understanding...

EMBO | EMBL Symposium

EMBL Heidelberg, Virtual

Registration
Will open shortly

4 May - 9 May 2025

Analysis and integration of transcriptome and proteome data

4 May 20252025CourseEMBL Heidelberg

Vladimir Benes, Raffaele Calogero, Daria Fijalkowska, Jeroen Krijgsveld, Lennard Martens

OverviewSponsors Overview Registration is not yet open for this event If you are interested in receiving more information please register your interest Course overview Systems biology is a still expanding field of research aiming to understand at the molecular level how cells tissues and organisms operate in their biological context Among the key technologies driving this forward are... OverviewSponsors Overview Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Course overview Systems biology is a still expanding field of research aiming to understand at the molecular level how cells, tissues and organisms operate in their biological context. Among the key technologies driving this forward are next-generation sequencing and proteomics, as they provide powerful means to determine global expression levels of genes and proteins. Both fields have matured to a degree that they have now become accessible to researchers in many areas of biology. During this course, participants will gain theoretical insight in the structure of sequencing and proteomic data, and they will receive training in data analysis for the annotation, quantification, and statistical analysis of gene and protein expression using...

EMBL Course

EMBL Heidelberg

Registration
Will open shortly

6 May - 9 May 2025

Theory and concepts in biology

6 May 20252025ConferenceEMBL Heidelberg, Virtual

Alexander Aulehla, Christina Hueschen, Jordi Garcia-Ojalvo, Sriram Ramaswamy, Kirsty Wan

The goal of this symposium is to assemble an interdisciplinary community and to provide a platform to discuss perspectives on the role of theory in biology and importantly also vice versa the impact that biology can have on theory... OverviewSponsorsAbout Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Symposium overview Recent progress in biology has led to an explosion of factual knowledge about the living world over a huge range of scales in space and time. Yet, many questions about how to make sense of this data remain across the entire diversity of the living world from the smallest bacterium to the ecosystems of the Serengeti. This meeting aims to bring together a diverse collection of researchers interested in finding ways to parlay this ever-increasing factual knowledge into a corresponding array of conceptual knowledge. The goal of this symposium is to assemble an interdisciplinary community and to provide a platform to discuss...

EMBO | EMBL Symposium

EMBL Heidelberg, Virtual

Registration
Will open shortly

12 May - 16 May 2025

Cancer genomics and transcriptomics

12 May 20252025CourseVirtual

EMBL-EBI Training

This course will focus on the analysis of data from genomic studies of cancer It will also highlight the application of transcriptomic analysis and single cell technologies in cancer Talks and interactive sessions will give an insight into the bioinformatic concepts required to analyse such data whilst practical sessions will enable the participants to apply statistical methods to the analysis of cancer genomics data under the guidance of the trainers Virtual courseParticipants will learn via a mix of pre recorded lectures live presentations and trainer Q A sessions Practical experience will be developed through group activities and trainer led computational exercises Live sessions will be delivered using Zoom with additional support and asynchronous communication via Slack Pre recorded material may be provided before the course starts that participants will need to watch read or work through to gain the most out of the actual training event In the week before the course there will be a brief induction session Computational practicals will run on EMBL EBI s virtual training infrastructure meaning participants will not require access to a powerful computer or install complex software on their own machines Participants will need to be available between the hours of 08 45 17 00 BST each day of the course Trainers will be available to assist answer questions and provide further explanations during these times... This course will focus on the analysis of data from genomic studies of cancer. It will also highlight the application of transcriptomic analysis and single-cell technologies in cancer. Talks and interactive sessions will give an insight into the bioinformatic concepts required to analyse such data, whilst practical sessions will enable the participants to apply statistical methods to the analysis of cancer genomics data under the guidance of the trainers.Virtual courseParticipants will learn via a mix of pre-recorded lectures, live presentations, and trainer Q&A sessions. Practical experience will be developed through group activities and trainer-led computational exercises. Live sessions will be delivered using Zoom with additional support and asynchronous communication via Slack.Pre-recorded material may be provided before the course starts that participants will need to watch,...

Course

Virtual

Registration
09 February 2025

13 May - 16 May 2025

Chromatin and epigenetics

13 May 20252025ConferenceEMBL Heidelberg, Virtual

Asifa Akhtar, Amanda Fisher, Dirk Schubeler, Bing Ren

Epigenetics refers to heritable changes in gene expression that do not involve changes to the underlying DNA sequence At least three systems including DNA methylation histone modifications and non coding RNAs ncRNA are considered to play fundamental roles in epigenetic regulation Research over the last two decades has uncovered the role of epigenetics in a variety of human disorders and fatal diseases Moreover influence of age environment lifestyle and disease state on epigenetic states is being increasingly appreciated and actively studied This conference provides an international forum for cutting edge research in chromatin and epigenetics It provides the focal hub for people to present their research and exchange ideas in a virtual format Renowned speakers will cover the latest advances in the field... OverviewSpeakersSponsorsMedia kit Overview Registration is not yet open for this event. If you are interested in receiving more information please register your interest. This conference will take place at EMBL Heidelberg, with the option to attend virtually. Conference overview Epigenetics refers to heritable changes in gene expression that do not involve changes to the underlying DNA sequence. At least three systems including DNA methylation, histone modifications and non-coding RNAs (ncRNA) are considered to play fundamental roles in epigenetic regulation. Research over the last two decades has uncovered the role of epigenetics in a variety of human disorders and fatal diseases. Moreover influence of age, environment, lifestyle, and disease state on epigenetic states is being increasingly appreciated and actively studied. This conference provides an international forum for cutting...

EMBL Conference

EMBL Heidelberg, Virtual

Registration
Will open shortly

18 May - 23 May 2025

Advanced fluorescence imaging techniques

18 May 20252025CourseEMBL Heidelberg

Manuel Gunkel, Aliaksandr Halavatyi, Joana Delgado Martins, Stefan Marawske

This practical course will cover advanced light microscopy techniques and participants will learn how to derive qualitative and quantitative insights on molecular mechanisms in cells and developing organisms Invited guest researchers together with experts from the EMBL and microscopy professionals will foster an intense information flow with a balance of lectures and practical workshops The focus of the course will be on the use of fluorescence microscopy to obtain information about protein localisation dynamics and functions at different spatial scales... OverviewSponsorsMedia Kit Overview Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Course overview This practical course will cover advanced light microscopy techniques and participants will learn how to derive qualitative and quantitative insights on molecular mechanisms in cells and developing organisms. Invited guest researchers together with microscopy experts from EMBL will foster an intense information flow with a balance of lectures and practical workshops. The focus of the course will be on the use of fluorescence microscopy to obtain information about localisation and functions of proteins and other bio-molecules at different spatial scales. Audience This course is directed towards researchers in the life sciences with access to light microscopy equipment, who have an immediate need to apply the...

EMBL Course

EMBL Heidelberg

Registration
Will open shortly

20 May - 23 May 2025

Introduction to metabolomics analysis

20 May 20252025CourseEMBL-EBI

EMBL-EBI Training

This course will provide an introduction to metabolomics through lectures and hands on sessions using publicly available data software and tools Participants will become familiar with standardised workflows as well as with the current state of experimental design data acquisition LC MS MS imaging processing and modelling In addition they will learn about community standards and sharing in metabolomics particularly through the use of EMBL EBI s MetaboLights repository and Galaxy infrastructure Participants will learn through hands on tutorials to use tools available for data analysis and data submission Additionally case studies will be discussed to show how to employ the week s learning... This course will provide an introduction to metabolomics through lectures and hands-on sessions, using publicly available data, software, and tools. Participants will become familiar with standardised workflows as well as with the current state of experimental design, data acquisition (LC-MS, MS imaging), processing, and modelling. In addition, they will learn about community standards and sharing in metabolomics, particularly through the use of EMBL-EBI’s MetaboLights repository and Galaxy infrastructure. Participants will learn through hands-on tutorials to use tools available for data analysis and data submission. Additionally, case studies will be discussed to show how to employ the week’s learning.

Course

EMBL-EBI

Registration
02 February 2025

26 May - 28 May 2025

Infection: pathogens, hosts and microbiomes

26 May 20252025ConferenceEMBL Heidelberg, Virtual

Maria Bernabeu, Pascale Cossart,Hiten Madhani, Kim Orth, Michael Way

OverviewSpeakersSponsors Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Registration is not yet open for this event If you are interested in receiving more information please register your interest Symposium overview Infectious diseases are among the most prevalent causes of human illness and death in the world Epidemics... OverviewSpeakersSponsors Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Symposium overview Infectious diseases are among the most prevalent causes of human illness and death in the world. Epidemics & pandemics have shaped human evolution and history, and although for a while there were considered a solved problem for the developed world, the recent past has showed us all why this is not the case. Antimicrobial resistance, global warming, human population size increase, modern lifestyles (urbanization, traveling), decrease of wild-life habitats for pathogen reservoirs all contribute to creating an ideal setting for infectious diseases becoming an even greater challenge in the future. This symposium will bring...

EMBO | EMBL Symposium

EMBL Heidelberg, Virtual

Registration
Will open shortly

1 June - 6 June 2025

Whole transcriptome data analysis

1 June 20252025CourseEMBL Heidelberg

Marco Beccuti, Vladimir Benes, Raffaele Calogero, Francesca Cordero

This course will teach the biological researchers how to analyse biological data sets using open source software Most of the analysis will be performed with docker4seq and rCASC packages which was developed to facilitate the use of computing demanding applications in the field of NGS data analysis... OverviewSponsors Overview Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Course overview This course will teach the biological researchers how to analyse biological data sets using open-source software. Most of the analysis will be performed with docker4seq and rCASC packages, which was developed to facilitate the use of computing demanding applications in the field of NGS data analysis. Docker4seq and rCASC packages use docker containers that embed demanding computing tasks (e.g. short reads mapping) into isolated containers. This approach provides multiple advantages: the user does not need to install all the software on its local server, the results generated by different containers can be organised in pipelines and reproducible research is guarantee by the possibility of sharing the docker images used...

Course

EMBL Heidelberg

Registration
Will open shortly

10 June - 13 June 2025

The ageing genome: from mechanisms to disease

10 June 20252025ConferenceEMBL Heidelberg, Virtual

George Garinis, Jaqueline Jacobs, Björn Schumacher, Agnel Sfeir

OverviewSpeakersSponsorsAboutMedia kit Overview Registration is not yet open for this event If you are interested in receiving more information please register your interest This conference will take place at EMBL Heidelberg with the option to attend virtually Symposium overview Ageing is often considered a complex phenotype that affects multiple organs and tissues in a time... OverviewSpeakersSponsorsAboutMedia kit Overview Registration is not yet open for this event. If you are interested in receiving more information please register your interest. This conference will take place at EMBL Heidelberg, with the option to attend virtually. Symposium overview Ageing is often considered a complex phenotype that affects multiple organs and tissues in a time-dependent manner. This may result in the aged population consuming a myriad of medications, each aimed to treat, but not cure, the affected tissue. Recent studies have demonstrated that the “Primary Hallmarks of Ageing” are a set of five molecular mechanisms that malfunction, independent of tissue type, and drive ageing. Hence, focusing on these five hallmarks simplifies the efforts to understand ageing-associated disease. This, the second edition of this symposium will bring together an all-new, international...

EMBO | EMBL Symposium

EMBL Heidelberg, Virtual

Registration
Will open shortly

16 June - 20 June 2025

Summer school in bioinformatics

16 June 20252025CourseEMBL-EBI

EMBL-EBI Training

This course provides an introduction to the use of bioinformatics in biological research giving you guidance for using bioinformatics in your work whilst also providing hands on training in tools and resources appropriate to your research You will initially be introduced to bioinformatics theory and practice including best practices for undertaking bioinformatics analysis data management and reproducibility You will be required to review some pre recorded material for their group project prior to the start of the course Group projectsA major element of this course is a group project where you ll be placed in small groups to work together on a challenge set by trainers from EMBL EBI and external institutes This allows you to explore the bioinformatics tools and resources available in your area of interest and apply them to a set problem providing you with hands on experience relevant to your own research The group work will culminate in a presentation session involving everyone on the final day of the course giving an opportunity for wider discussion on the benefits and challenges of working with biological data Groups are mentored and supported by the trainers who set the initial challenge but the groups will be responsible for driving their projects forward with all members expected to take an active role Groups are pre organised before the course and all group members will be sent some short homework in preparation for your project work prior to the start of the course Basic outlines of the projects on offer this year are given below In your application you must indicate your first and second choice of project based on which you think would benefit your research most Not all projects may be offered and final decisions on which projects will be run during the course will be made based on the number of applicants per project Most of the projects cover mammalian data sets however in many cases the methods and approaches taught are transferable to data from various species The projects are currently under development... This course provides an introduction to the use of bioinformatics in biological research, giving you guidance for using bioinformatics in your work whilst also providing hands-on training in tools and resources appropriate to your research.You will initially be introduced to bioinformatics theory and practice, including best practices for undertaking bioinformatics analysis, data management, and reproducibility. You will be required to review some pre-recorded material for their group project prior to the start of the course.Group projectsA major element of this course is a group project, where you'll be placed in small groups to work together on a challenge set by trainers from EMBL-EBI and external institutes. This allows you to explore the bioinformatics tools and resources available in your area of interest and apply them to a set problem, providing you with hands-on experience...

Course

EMBL-EBI

Registration
02 March 2025

16 June - 17 June 2025

In science we trust?

16 June 20252025ConferenceEMBL Heidelberg

Lucia von Bredow

This conference will analyse the importance of public trust in science in a post truth society from public involvement in science to implications on funding and resource allocation and the political consequences of losing societal trust and buy in Above all it will ask what we role we can all play in shaping the future path of increased societal trust in science... OverviewSponsors Overview This conference will take place as in-person meeting onsite at EMBL Heidelberg. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Conference overview We live in an era characterised by dazzling scientific and technological progress on an unprecedented scale. From the application of new gene editing techniques, pioneering stem cell research, or rapid vaccine development to emerging technologies such as AI or organoid research, advances in life sciences offer a myriad of potential benefits to society.  However, these scientific endeavours exist against a backdrop of misinformation and disinformation in the scientific arena, which have the potential to cast a shadow on the public perception of science. From attitudes surrounding scientific issues in the pandemic, highly publicised...

EMBL Science and Society Conference

EMBL Heidelberg

Registration
Will open shortly

24 June - 26 June 2025

Data visualisation for biology

24 June 20252025CourseEMBL-EBI

EMBL-EBI Training

This course will give insights into and practical experience in data visualisation for exploring complex and multi dimensional biological data Biological and life sciences data often consists of multiple dimensions a combination of numerical values ordered data categories and time series To make sense of this data simple plots like scatterplots barcharts and boxplots are often not enough Still visualisation is critical in gaining deep insight into the data This is why many custom visualisations originated in the biological field In this course we will dive into the topic of visualisation of complex biological data and how it can be used to gain insight into and get a feel for a dataset so that targeted analyses can be defined It will be delivered through a mixture of lectures and workshop sessions and will provide hands on experience in developing visualisations The course will focus on working with omics e g genomics transcriptomics data rather than e g imaging data... This course will give insights into, and practical experience in, data visualisation for exploring complex and multi-dimensional biological data.Biological and life sciences data often consists of multiple dimensions: a combination of numerical values, ordered data, categories, and time-series. To make sense of this data, simple plots like scatterplots, barcharts, and boxplots are often not enough. Still, visualisation is critical in gaining deep insight into the data. This is why many custom visualisations originated in the biological field.In this course, we will dive into the topic of visualisation of complex biological data and how it can be used to gain insight into and get a "feel" for a dataset, so that targeted analyses can be defined. It will be delivered through a mixture of lectures and workshop sessions, and will provide hands-on experience in developing visualisations. The...

Course

EMBL-EBI

Registration
09 March 2025

24 June - 27 June 2025

New approaches and concepts in microbiology

24 June 20252025ConferenceEMBL Heidelberg, Virtual

Pascale Cossart, Sophie Helaine, KC Huang, Michael Laub, Nassos Typas

This symposium will cover a broad range of topics in microbiology including antibiotic related research bacterial communities and microbiome cell biology regulation signalling pathogenesis and evolution Emphasis will be placed on novel approaches and technologies from systems based to single cell that drive each field or have the potential to revolutionise future research in microbiology... OverviewSponsorsMedia kitAbout Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Symposium overview This symposium is the seventh edition of a successful series started in 2013 and held biannually since, establishing itself as a must-attend fixture in the calendar for scientists working with bacteria and new technologies. The meeting covers a broad range of cutting-edge topics in microbiology, featuring diverse research. Emphasis is placed on novel approaches and technologies (from systems-based to single-cell) that drive each field or have the potential to revolutionize future research in microbiology. The meeting is always oversubscribed and manages to bring together scientists from different areas, who normally...

EMBO | EMBL Symposium

EMBL Heidelberg, Virtual

Registration
Will open shortly

7 July - 11 July 2025

Systems biology: from large datasets to biological insight

7 July 20252025CourseEMBL-EBI

EMBL-EBI Training

This course covers the use of computational tools to extract biological insight from omics datasets The content will explore a range of approaches ranging from network inference and data integration to machine learning and logic modelling that can be used to extract biological insights from varied data types Together these techniques will provide participants with a useful toolkit for designing new strategies to extract relevant information and understanding from large scale biological data The motivation for running this course is a result of advances in computer science and high performance computing that have led to groundbreaking developments in systems biology model inference With the comparable increase of publicly available large scale biological data the challenge now lies in interpreting them in a biologically valuable manner Likewise machine learning approaches are making a significant impact in our analysis of large omics datasets and the extraction of useful biological knowledge... This course covers the use of computational tools to extract biological insight from omics datasets. The content will explore a range of approaches – ranging from network inference and data integration to machine learning and logic modelling – that can be used to extract biological insights from varied data types. Together these techniques will provide participants with a useful toolkit for designing new strategies to extract relevant information and understanding from large-scale biological data.The motivation for running this course is a result of advances in computer science and high-performance computing that have led to groundbreaking developments in systems biology model inference. With the comparable increase of publicly-available, large-scale biological data, the challenge now lies in interpreting them in a biologically valuable manner. Likewise, machine learning approaches are...

Course

EMBL-EBI

Registration
16 March 2025

14 July - 18 July 2025

Proteomics bioinformatics

14 July 20252025CourseEMBL-EBI

EMBL-EBI Training

This course provides hands on training in the basics of mass spectrometry MS and proteomics bioinformatics You will receive training on how to use search engines and post processing software quantitative approaches MS data repositories the use of public databases for protein analysis annotation of subsequent protein lists and incorporation of information from molecular interaction and pathway databases The practical elements of the course will take raw data from a proteomics experiment and analyse it You will be able to go from MS spectra to identifying and quantifying peptides and finally to obtaining lists of protein identifiers that can be analysed further using a wide range of resources The final aim is to provide you with the practical bioinformatics knowledge you need to go back to the lab and process your own data when collected This course is organised in association with the Vlaams Instituut voor Biotechnologie VIB the Flemish Institute for Biotechnology Pre recorded material may be provided before the course starts that you will need to watch read or work through to gain the most out of the actual training event... This course provides hands-on training in the basics of mass spectrometry (MS) and proteomics bioinformatics. You will receive training on how to use search engines and post-processing software, quantitative approaches, MS data repositories, the use of public databases for protein analysis, annotation of subsequent protein lists, and incorporation of information from molecular interaction and pathway databases.The practical elements of the course will take raw data from a proteomics experiment and analyse it. You will be able to go from MS spectra to identifying and quantifying peptides, and finally to obtaining lists of protein identifiers that can be analysed further using a wide range of resources. The final aim is to provide you with the practical bioinformatics knowledge you need to go back to the lab and process your own data when collected.This course is organised in association...

Course

EMBL-EBI

Registration
06 April 2025

3 September - 7 September 2025

Protein synthesis and translational control

3 September 20252025ConferenceEMBL Heidelberg, Virtual

Alfredo Castello, Fátima Gebauer

This conference focuses on the process of protein synthesis from the molecular and structural understanding of the translational machinery to its regulation its implications in cell and organismal biology and its alteration in disease... OverviewSponsors Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Conference overview Mechanisms that shape cellular proteomes are critical for life. This conference focuses on the process of protein synthesis, from the molecular and structural understanding of the translational machinery to its regulation, its implications in cell and organismal biology, and its alteration in disease. The regulation of mRNA translation is critical to maintaining cell homeostasis and mediates cellular responses to environmental, physiological, and pathological cues. Given the central importance of protein synthesis, it is unsurprising that dysregulation or defects in mRNA translation are widely linked to disease, including cancer,...

Conference

EMBL Heidelberg, Virtual

Registration
Will open shortly

9 September - 12 September 2025

Developmental metabolism: flows of energy, matter, and information

9 September 20252025ConferenceEMBL Heidelberg, Virtual

Alexander Aulehla, Heather Christofk, Heidi Lempradl, Jonathan Rodenfels

This meeting will create an intellectual space to exchange ideas across disciplines and help form a vibrant diverse community at the interphase between developmental biology molecular metabolism mathematics and physics... OverviewSponsors Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Event details to be confirmed, pending EMBO funding application. Conference overview The fundamental question of the role of metabolism in development has seen a revival in interest. This is fueled by recent work, shedding new light onto previously unrecognised roles of metabolism. This work revealed the intricate relationship between energy flux, spatial and temporal control of metabolites, the environment and embryogenesis. This emerging view is stimulating research designed to answer fundamental questions including: How does the cellular machinery process information linked to the flow of energy and matter? How does metabolic activity impact and...

Conference

EMBL Heidelberg, Virtual

Registration
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16 September - 19 September 2025

The human microbiome

16 September 20252025ConferenceEMBL Heidelberg, Virtual

Mani Arumugam, Ami Bhatt, Peer Bork, Nicola Segata

OverviewSponsorsAbout Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Registration is not yet open for this event If you are interested in receiving more information please register your interest Symposium overview Human microbiota the collection of microbes living in and on our body have a significant impact on human health and... OverviewSponsorsAbout Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Symposium overview Human microbiota – the collection of microbes living in and on our body – have a significant impact on human health and well-being. They have been associated with numerous diseases, yet we are still far from understanding their role in the context of lifestyle and genetics. Various initiatives are underway around the world to survey the human microbiota at several body sites, characterise them, understand their interactions with the human hosts, elucidate their role in diseases, and design possible therapeutic or dietary interventions. There is a new wave of studies mining the human microbiota for health-relevant bioactive...

EMBO | EMBL Symposium

EMBL Heidelberg, Virtual

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6 October - 10 October 2025

Metagenomics bioinformatics at MGnify

6 October 20252025CourseEMBL-EBI

EMBL-EBI Training

Learn about the tools processes and analysis approaches used by MGnify in the field of genome resolved metagenomics This course will cover the use of publicly available resources to manage share analyse and interpret metagenomics data focussing primarily on the assembly based approaches used in MGnify analysis The delivered content will involve participants learning via live lectures and presentations followed by live Q As with the trainers Practical experience will be developed in group activities and in computational exercises run using containerised tools on our training infrastructure This course is currently under development please check back again soon for further details... Learn about the tools, processes, and analysis approaches used by MGnify in the field of genome-resolved metagenomics. This course will cover the use of publicly available resources to manage, share, analyse, and interpret metagenomics data, focussing primarily on the assembly-based approaches used in MGnify analysis. The delivered content will involve participants learning via live lectures and presentations, followed by live Q&As with the trainers. Practical experience will be developed in group activities and in computational exercises run using containerised tools on our training infrastructure. This course is currently under development, please check back again soon for further details.

Course

EMBL-EBI

Registration
22 June 2025

8 October - 11 October 2025

Seeing is believing: imaging the molecular processes of life

8 October 20252025ConferenceEMBL Heidelberg, Virtual

Jan Ellenberg, Jennifer Lippincott-Schwartz, Satyajit Mayor, Atsushi Miyawaki

OverviewSponsors Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Registration is not yet open for this event If you are interested in receiving more information please register your interest Conference overview The molecular processes of life are naturally dynamic in space and time from the atomic to the organismal level The rapid... OverviewSponsors Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Conference overview The molecular processes of life are naturally dynamic in space and time from the atomic to the organismal level. The rapid development of imaging methods across the full scale of biological organisation is revolutionising our ability to visualise the inner workings of macromolecular complexes, organelles, cells, tissues, organs and whole organisms. Being able to see biological processes unfold in real time allows us to understand the mechanisms of life as well as disease.The symposium will bring together the leading developers of imaging methods with cutting-edge applications that illustrate how imaging can answer biological...

Conference

EMBL Heidelberg, Virtual

Registration
Will open shortly

13 October - 17 October 2025

Liquid biopsies

13 October 20252025CourseEMBL Heidelberg

Anders Stahlberg, Martin Dalin

OverviewSponsors Overview Registration is not yet open for this event If you are interested in receiving more information please register your interest Course Overview There is an increasing interest and need to analyse biomarkers in liquid biopsies including basic research and clinical applications Liquid biopsies have several advantages including being minimally invasive allowing... OverviewSponsors Overview Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Course Overview There is an increasing interest and need to analyse biomarkers in liquid biopsies, including basic research and clinical applications. Liquid biopsies have several advantages including being minimally invasive, allowing repeated sampling and sampling is often clinical routine. This course will provide an overview of the several techniques to detect and analyse liquid biopsy-based analytes such as circulating tumour cells, cell-free tumor-DNA (ctDNA), miRNA, extracellular vesicles, mRNA, carbohydrates and proteins. Participants will be introduced to all aspects ranging from proper sampling through analyte analysis and final data analysis. Experimentally, we will demonstrate ultrasensitive ctDNA analysis using sequencing...

EMBL Course

EMBL Heidelberg

Registration
Will open shortly

22 October - 25 October 2025

Organoids: model organism development and discovery in 3D

22 October 20252025ConferenceEMBL Heidelberg, Virtual

Meritxell Huch, Karl R. Koehler, Madeline Lancaster, Esther Schnapp

The aim of this meeting is to bring together researchers from different fields to enhance our understanding of how organoids can be formed and maintained how they can be used to study disease and how we might eventually use them to regenerate and replace human organ tissue... OverviewSponsorsAbout Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Symposium overview The ability to grow tissues from stem cells in 3D culture to generate so-called organoids has revolutionised the study of tissue biology, especially human biology. This exciting technology has great potential for drug discovery and regenerative medicine. Because organoids model a variety of tissues with remarkably high fidelity, they allow for new discoveries in human development, homeostasis, regeneration, and disease. This symposium will bring together the leading researchers in this field, representing the premier conference for this research community, and providing a much-anticipated program that demonstrates how this...

EMBO | EMBL Symposium

EMBL Heidelberg, Virtual

Registration
Will open shortly

27 October - 31 October 2025

Structural bioinformatics

27 October 20252025CourseVirtual

EMBL-EBI Training

This course provides a guide to the commonly used methods and tools in structural bioinformatics to analyse and interpret experimentally determined and AI predicted macromolecular structure data Structural biology determining the three dimensional shapes of biomacromolecules and their complexes can tell us a lot about how these molecules function and the roles they play within a cell Data derived from structure determination experiments and Artificial Intelligence AI assisted structure prediction enables life science researchers to address a wide variety of questions This course explores bioinformatics data resources and tools for the investigation analysis and interpretation of both experimentally determined and predicted biomacromolecular structures It will focus on how best to analyse and interpret available structural data to gain useful information given specific research contexts The course content will also cover predicting function and exploring interactions with other macromolecules This course is currently under development please check back again soon for further details... This course provides a guide to the commonly used methods and tools in structural bioinformatics to analyse and interpret experimentally determined and AI-predicted macromolecular structure data. Structural biology, determining the three-dimensional shapes of biomacromolecules and their complexes, can tell us a lot about how these molecules function and the roles they play within a cell. Data derived from structure determination experiments and Artificial Intelligence (AI)-assisted structure prediction enables life-science researchers to address a wide variety of questions.   This course explores bioinformatics data resources and tools for the investigation, analysis, and interpretation of both experimentally determined and predicted biomacromolecular structures. It will focus on how best to analyse and interpret available structural data to gain useful information given...

Course

Virtual

Registration
27 July 2025

28 October - 30 October 2025

The epitranscriptome

28 October 20252025ConferenceEMBL Heidelberg, Virtual

Michaela Frye, Tsutomiu Suzuki, Chengqi Yi

OverviewSponsors Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Registration is not yet open for this event If you are interested in receiving more information please register your interest Event details to be confirmed pending EMBO funding application Conference Overview The regulation of the transcriptome is key to cellular... OverviewSponsors Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Event details to be confirmed, pending EMBO funding application. Conference Overview The regulation of the transcriptome is key to cellular processes that underpin cell biology, development and tissue function. All classes of cellular RNA are subject to post-transcriptional modification, be it by direct chemical modification, editing or non-templated nucleotide additions. Now in its fourth edition, the ‘Epitranscriptome’ meeting first held at EMBL in 2016 (and repeated in 2018 then in 2022 as a virtual conference) was the first RNA modification-dedicated meeting with the focus on mammalian systems. It is now established that biochemical...

EMBL Conference

EMBL Heidelberg, Virtual

Registration
Will open shortly

4 November - 7 November 2025

The mobile genome: genetic and physiological impacts of transposable elements

4 November 20252025ConferenceEMBL Heidelberg, Virtual

Deborah Bourc'his, Josefa Gonzalez Perez, Joseph Peters, Julius Brennecke

OverviewSponsors Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Registration is not yet open for this event If you are interested in receiving more information please register your interest Event details to be confirmed pending EMBO funding application Conference overview Disparaged as selfish DNA for decades it s now clear... OverviewSponsors Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Event details to be confirmed, pending EMBO funding application. Conference overview Disparaged as “selfish DNA” for decades, it’s now clear that transposable elements (TEs) underlie the remarkably dynamic nature of bacterial, plant, and animal genomes. This conference builds on the highly successful 2021 and 2023 Mobile Genome EMBO workshops and has emerged as the major European venue in this ever-growing cross-disciplinary research field. The 2025 Mobile Genome conference will assemble recognized experts from diverse disciplines (e.g., genomics, epigenetics, structural biology, evolutionary biology, and developmental biology), as...

Conference

EMBL Heidelberg, Virtual

Registration
Will open shortly

11 November - 14 November 2025

Cancer genomics

11 November 20252025ConferenceEMBL Heidelberg, Virtual

Isidro Cortes Ciriano, Young Seok Ju

OverviewSponsors Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Registration is not yet open for this event If you are interested in receiving more information please register your interest Conference overview This meeting will provide an opportunity to learn about and keep up to date with the rapidly progressing area of cancer... OverviewSponsors Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Conference overview This meeting will provide an opportunity to learn about and keep up to date with the rapidly progressing area of cancer genomics. We aim to bring together scientists from across several disciplines connected with cancer research, for a unique opportunity to interact and stimulate further integration of these efforts. What past participants say about the conference “The EMBL ‘Cancer genomics’ conference was an exceptional experience, perfectlysynthesizing scientific and technical innovation guided by leading scientists and researchers in the field. It provided a great opportunity to learn and network with...

EMBL Conference

EMBL Heidelberg, Virtual

Registration
Will open shortly

17 November - 21 November 2025

Genome bioinformatics: from short- to long-read sequencing

17 November 20252025CourseEMBL-EBI

EMBL-EBI Training

A guide to the technology analysis workflows tools and resources for next generation sequencing data analysis This course will provide insights and training into how biological knowledge can be derived from genomics experiments and explain different approaches in analysing such data The main focus will be on introducing sequence informatics re sequencing differences between short and long read sequencing and variant calling during the analysis of higher eukaryotes with an emphasis on human genetic research Throughout the week more advanced topics will introduce the creation of pipelines automation and the scaling up of analysis experiments Practical sessions will be run on datasets prepared by the trainers not on personal research data Participants will learn how to process these training datasets and to apply appropriate statistical methods in their analyses This course is currently under development please check back again soon for further details... A guide to the technology, analysis workflows, tools, and resources for next-generation sequencing data analysis. This course will provide insights and training into how biological knowledge can be derived from genomics experiments and explain different approaches in analysing such data. The main focus will be on introducing sequence informatics, re-sequencing, differences between short- and long-read sequencing, and variant calling during the analysis of higher-eukaryotes, with an emphasis on human genetic research. Throughout the week, more advanced topics will introduce the creation of pipelines, automation, and the scaling-up of analysis experiments. Practical sessions will be run on datasets prepared by the trainers, not on personal research data. Participants will learn how to process these training datasets and to apply appropriate statistical methods in their analyses....

Course

EMBL-EBI

Registration
04 August 2025

18 November - 21 November 2025

Cell biology of the nucleus

18 November 20252025ConferenceEMBL Heidelberg, Virtual

Simone Koehle, Patrick Lusk, Thomas Quail, Sara Wickström

OverviewSponsors Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Registration is not yet open for this event If you are interested in receiving more information please register your interest Conference overview The nucleus lies at the literal and figurative heart of the cell as the one organelle that all eukaryotes share it is over... OverviewSponsors Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Conference overview The nucleus lies at the literal and figurative heart of the cell – as the one organelle that all eukaryotes share, it is over 2 billion years old and integrated with every aspect of cellular function, from mechanosensing and genome regulation to membrane trafficking and cell division. Although the role of the nucleus in organising, housing and protecting the genome frequently takes centre stage, much remains to be discovered about the cellular physiology of this unique organelle studied in its own right rather than just as a passive scaffold for chromatin. This meeting will bring together a group of scientists spanning the fields...

Conference

EMBL Heidelberg, Virtual

Registration
Will open shortly

25 November - 27 November 2025

Managing a bioinformatics core facility

25 November 20252025CourseEMBL-EBI

EMBL-EBI Training

This knowledge exchange workshop is an opportunity for managers of bioinformatics core facilities to learn from EMBL EBI s service teams and from each other These facilities play an essential role in enabling research in the molecular life sciences The landscape is constantly evolving as new research tools emerge as experiments become increasingly data intensive and as their clients experimental researchers become more exposed to the power of data driven biology This course will allow participants to share experiences discuss challenges and solutions that they face and plan ways to cope with the ever changing demands raised by the molecular life science field It will include sessions to learn from bioinformatics service providers hear how others have tackled common problems and work together to design core services resource them and measure their impact This course is currently under development please check back again soon for further details... This knowledge exchange workshop is an opportunity for managers of bioinformatics core facilities to learn from EMBL-EBI’s service teams, and from each other. These facilities play an essential role in enabling research in the molecular life sciences. The landscape is constantly evolving as new research tools emerge, as experiments become increasingly data-intensive, and as their clients – experimental researchers – become more exposed to the power of data-driven biology. This course will allow participants to share experiences, discuss challenges and solutions that they face, and plan ways to cope with the ever-changing demands raised by the molecular life science field. It will include sessions to learn from bioinformatics service providers, hear how others have tackled common problems, and work together to design core services, resource them, and measure their impact. This course is...

Course

EMBL-EBI

Registration
10 August 2025

2 December - 5 December 2025

Computational structural biology

2 December 20252025ConferenceEMBL Heidelberg, Virtual

Rommie Amaro, Charlotte Deane, Jan Kosinski, Christine Orengo, Sameer Velankar

This conference will update on the impact of AI based structure prediction provide a forum to present new methods and applications build a wider community by integrating the new scientists now massively joining the field and open a platform to discuss future directions and opportunities... OverviewSponsors Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Event details to be confirmed, pending EMBO funding application. Conference overview The field of computational structural biology is undergoing a revolution. AlphaFold, a program based on Artificial Intelligence (AI), has transformed the structural modelling of proteins and protein complexes by reaching accuracy similar to experimental structures. Over 200 million structural models have already been released in AlphaFold Database. Following AlphaFold, other protein modelling programs proliferated from researchers worldwide. AI has started advancing RNA modeling too. The wealth of protein models has sparked an explosion of new tools for structural...

Conference

EMBL Heidelberg, Virtual

Registration
Will open shortly

7 December - 12 December 2025

Genome engineering: CRISPR/Cas in cells and mice

7 December 20252025CourseEMBL Heidelberg

Silke Deckert, Neil Humphreys, Kristof Kersse, Birgit Koch, Elisabeth Zielonka

OverviewSponsorsMedia kit Overview Registration is not yet open for this event If you are interested in receiving more information please register your interest Course overview This course will provide training in genome editing and cell engineering in mammalian cells and mouse embryos using the highly efficient CRISPR Cas9 system Participants will learn design of CRISPR targets using... OverviewSponsorsMedia kit Overview Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Course overview This course will provide training in genome editing and cell engineering in mammalian cells and mouse embryos using the highly efficient CRISPR/Cas9 system. Participants will learn design of CRISPR targets using bioinformatics tools, generation of gene knock-outs/knock-ins, and target validation using the most current technologies. The course will be split into two groups (mammalian cells OR mice) based on participants’ expertise. Please note that all participants are expected to engage in all sessions. Participants should plan for approximately 1 hour extra per day for self paced learning modules. Audience This course is aimed at researchers who are familiar with basic molecular and cell biology...

EMBL Course

EMBL Heidelberg

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