17 August - 25 August 2026
Advances in cryo-electron microscopy and 3D image processing
Tanmay Bharat, Svetlana Dodonova, Sebastian Eustermann, Simone Mattei, Kelly Nguyen
Description OverviewSpeakersPreliminary programmePractical informationSponsorsMedia kit Overview Course overview Over the past decade cryo electron microscopy has transformed our understanding of biomolecular structures across multiple spatial scales from atoms to cells Technological advances have provided unprecedented insights from atomic resolution structures of biologically heterogeneous states to the first glimpses into the molecular sociology of a cell Yet emerging breakthroughs such as time resolved approaches novel correlated imaging technologies and AI driven image processing highlight the potential of cryo EM for another leap forward To realise this potential in depth advanced training is essential for driving innovation and developing new technologies to tackle emerging biological challenges This course offers a comprehensive foundation in advanced single particle and cellular tomography techniques covering the entire workflow from sample preparation to data collection and image processing Participants will have the chance to meet the leaders in the field with unique 1 1 meetings and informal social programme Audience Designed for PhD students and postdoctoral researchers with basic experience in cryo EM and 3D image processing the course will equip participants with the expertise to integrate state of the art single particle analysis and tomography into their research It will also prepare them to critically discuss their knowledge with peers and ultimately contribute to the development of novel cryo EM methodologies beyond the current state of the art Modules resources Single particle reconstruction cisTEM Relion cryoSPARC Subtomogram averaging RELION 5 Warp Atomic models model building and integrative modeling Session at the microscopes cryo EM ET and cryo FIB Latest developments in instrumentations Tomogram reconstruction template matching Learning outcomes The course will enable participants to seamlessly integrate single particle analysis and tomography approaches to their cutting edge research disseminate their gained expertise to colleagues and to innovate cryo EM methods beyond the state of the art What past participants say about the course The course was among the best I ve attended on this topic It was an exceptional opportunity for both learning and networking Fernanda Sala UMG and MPI Germany This event has been granted the following EMBO sustainability badge Grade 1 of 3 Speakers Speakers trainers and staff Anastasiia Babenko EMBL Heidelberg Germany Martin Beck Max Planck Institute of Biophysics Germany Tanmay Bharat MRC Laboratory of Molecular Biology United Kingdom Bridget Carragher Biohub Imaging Institute USA Virtual speaker Svetlana Dodonova EMBL Heidelberg Germany Max Dreimann EMBL Heidelberg Germany Johannes Elferich University of Massachusetts Medical School USA Sebastian Eustermann EMBL Heidelberg Germany Friedrich F rster Utrecht University Netherlands Simon Fromm EMBL Heidelberg Germany Nikolaus Grigorieff University of Massachusetts Medical School USA Matthew Hartley EMBL EBI United Kingdom Virtual speaker Thomas Hoffmann EMBL Heidelberg Germany Dominik Hreb k Max Planck Institute of Biochemistry Germany Arjen Jakobi Delft University of Technology Netherlands Kiarash Jamali MRC Laboratory of Molecular Biology United Kingdom Alex Kelleher EMBL Heidelberg Germany Dari Kimanius Chan Zuckerberg Institute for Advanced Biological Imaging USA Virtual speaker Jan Kosinski EMBL Hamburg Germany Wanda Kukulski University of Bern Switzerland Julia Mahamid EMBL Heidelberg Germany Kyle Morris EMBL EBI United Kingdom Virtual speaker Bonnie Murphy Max Planck Institute of Biophysics Germany Kelly Nguyen MRC Laboratory of Molecular Biology United Kingdom Cristina Paulino Heidelberg University Germany J rgen Plitzko Max Planck Institute of Biophysics Germany Euan Pyle EMBL Heidelberg Germany Alexis Rohou Genentech USA Virtual speaker Higor Rosa EMBL Heidelberg Germany Carsten Sachse Forschungszentrum J lich GmbH Germany Sjors Scheres MRC Laboratory of Molecular Biology United Kingdom Virtual speaker Yi Sun EMBL Heidelberg Germany Dimitry Tegunov Genentech USA Bogdan Toader MRC Laboratory of Molecular Biology United Kingdom Davide Torre Max Planck Institute of Biochemistry Germany Sonja Welsch Max Planck Institute of Biophysics Germany Georg Wolff EMBL Heidelberg Germany Zhengyi Yang EMBL Heidelberg Germany Scientific organisers Tanmay Bharat MRC Laboratory of Molecular Biology United Kingdom Svetlana Dodonova EMBL Heidelberg Germany Sebastian Eustermann EMBL Heidelberg Germany Simone Mattei EMBL Heidelberg Germany Kelly Nguyen MRC Laboratory of Molecular Biology United Kingdom Course organisers Catherine Casas Saavedra Course and Conference Manager EMBL Heidelberg Germany Michelle Steinhauer Scientific Training Officer EMBL Heidelberg Germany Preliminary programme Are you on social media Post using EMBOCryoEM and don t forget to tag EMBLEvents Some pre course work such as watching pre recordings and protocol reading with estimated time 0 10 hours will be required and will be shared in advance of the course Some speakers may need to join virtually to give their lecture or Q A and the programme is subject to change Day 1 Monday 17 August 2026 Time Europe Berlin SessionTime13 00 13 15Bus from hotel to EMBL ATC Entrance13 15 13 55Registration and refreshmentsCourtyard Room A B13 55 14 05Introduction and housenote slidesSebastian Eustermann EMBL Heidelberg GermanyCourtyard Room A B14 05 14 15Course overviewCourtyard Room A B14 15 15 15Participants flash talksCourtyard Room A B15 15 15 45Coffee breakCourtyard Room A B15 45 16 45Participants flash talksCourtyard Room A B16 45 18 00Lecture New technologies for structural cell biologyBridget Carragher Biohub Imaging Institute USA Virtual speaker Courtyard Room A B18 00 19 00DinnerEMBL Canteen19 00Bus to hotel Day 2 Tuesday 18 August 2026 Time Europe Berlin SessionLocation08 20 08 30Bus from hotel to EMBL ATC Entrance08 30 08 35Overview of the dayCourtyard Room A B08 35 09 00Emerging technologies from leading R D industry expertsCourtyard Room A B09 00 10 15Lecture Cryo EM image formation and opticsCarsten Sachse Forschungszentrum J lich GmbH GermanyCourtyard Room A B10 15 10 45Coffee breakCourtyard Room A B10 45 12 00Lecture Next generation microscope hardwareJ rgen Plitzko Max PLanck Institute of Biochemistry GermanyCourtyard Room A B12 00 13 00Lunch breakEMBL Canteen13 00 14 15EMBO Young Investigator Lecture Perspectives on cryoEM single particle sample preparation acquisitionKelly Nguyen MRC Laboratory of Molecular Biology United KingdomCourtyard Room A B14 15 15 30Lecture Perspectives on cryoET sample preparation acquisitionJulia Mahamid EMBL Heidelberg GermanyCourtyard Room A B15 30 16 00Coffee breakCourtyard Room A B16 00 17 15Lecture Fundamentals in cryoEM image processingSjors Scheres MRC Laboratory of Molecular Biology United Kingdom Virtual speaker Courtyard Room A B17 15 18 30EMBO Young Investigator Lecture Fundamentals in cryoET image processingTanmay Bharat MRC Laboratory of Molecular Biology United KingdomCourtyard Room A B18 30 19 30DinnerEMBL Canteen19 30 20 45Lecture Fundamentals in AIDari Kimanius Chan Zuckerberg Institute for Advanced Biological Imaging USA Virtual speaker Courtyard Room A B20 45Bus to hotel Day 3 Wednesday 19 August 2026 Time Europe Berlin SessionLocation08 20 08 30Bus from hotel to EMBL ATC Entrance08 30 08 35Overview of the day08 35 08 55Emerging technologies From cells to molecules How cryo electron microscopy technologies are transforming structural biologyJana m dov TESCAN GroupCourtyard Room A B08 55 10 10Lecture Reconstructing analytical signals for elemental mapping in biological samplesBonnie Murphy Max Planck Institute of Biophysics GermanyCourtyard Room A B10 10 10 40Coffee breakCourtyard Room A B10 40 11 55Lecture Advances in AI based image processing and modelling of supra molecular assembliesMartin Beck Max Planck Institute of Biophysics GermanyCourtyard Room A B11 55 12 55Lunch breakEMBL Canteen12 55 15 25Practical session ASession 1 on Fundamentals in analyzing macromolecular heterogeneity in RELIONSebastian Eustermann EMBL Heidelberg GermanyKelly Nguyen MRC Laboratory of Molecular Biology United KingdomSession 2 on Advanced cryoEM single particle analysis cyroSPARC SPA topicDominik Hreb k Max Planck Institute of Biochemistry GermanyDavide Torre Max Planck Institute of Biochemistry GermanySession 3 on Advanced cryoET subtomogram averaging Relion Tomo topicTanmay Bharat MRC Laboratory of Molecular Biology United KingdomEuan Pyle EMBL Heidelberg GermanyBogdan Toader MRC Laboratory of Molecular Biology United KingdomSession 4 on Advanced cryoET subtomogram averaging WARP M Tomo topicMax Dreimann EMBL Heidelberg GermanyHigor Rosa EMBL Heidelberg GermanyDimitry Tegunov Genentech USASession 5 on Model building refinement and validationArjen Jakobi Delft University of Technology NetherlandsSession 1 Courtyard RoomsSession 2 Flex Lab BSession3 Flex Lab ASession 4 Computer Training LabSession 5 Helix A Seminar Room15 25 15 55Coffee breakCourtyard Room A B15 55 18 25Practical session BSession 1 on Fundamentals in analyzing macromolecular heterogeneity in RELIONSebastian Eustermann EMBL Heidelberg GermanyDari Kimanius Chan Zuckerberg Institute for Advanced Biological Imaging USA Virtual trainer Kelly Nguyen MRC Laboratory of Molecular Biology United KingdomSession 2 on Advanced cryoEM single particle analysis cyroSPARC SPA topicDominik Hreb k Max Planck Institute of Biochemistry GermanyDavide Torre Max Planck Institute of Biochemistry GermanySession 3 on Advanced cryoET subtomogram averaging Relion Tomo topicTanmay Bharat MRC Laboratory of Molecular Biology United KingdomEuan Pyle EMBL Heidelberg GermanyBogdan Toader MRC Laboratory of Molecular Biology United KingdomSession 4 on Advanced cryoET subtomogram averaging WARP M Tomo topicMax Dreimann EMBL Heidelberg GermanyHigor Rosa EMBL Heidelberg GermanyDimitry Tegunov Genentech USASession 5 on Model building refinement and validationArjen Jakobi Delft University of Technology NetherlandsSession 1 Courtyard RoomsSession 2 Flex Lab BSession3 Flex Lab ASession 4 Computer Training LabSession 5 Helix A Seminar Room18 25 19 25DinnerEMBL Canteen19 25 20 40Lecture To be confirmedTo be confirmedCourtyard Room A B20 40 21 10Discussion round Hot topics recent breakthroughs and emerging technologiesCourtyard Room A B21 10Bus to hotel Day 4 Thursday 20 August 2026 Time Europe Berlin SessionLocation08 20 08 30Bus from hotel to EMBL ATC Entrance08 30 08 35Overview of the day08 35 09 50Lecture Advances in cryoET particle identificationFriedrich F rster Utrecht University The NetherlandsCourtyard Room A B09 50 10 20Coffee breakCourtyard Room A B10 20 11 35Lecture High resolution by cryo ET subtomogram averagingDimitry Tegunov Genentech USACourtyard Room A B11 35 12 05Panel discussion Software and image processingPanel leaders Tanmay Bharat MRC Laboratory of Molecular Biology United Kingdom and Sebastian Eustermann EMBL Heidelberg GermanyCourtyard Room A B12 05 13 05Technology Lunchsponsored by PuxanoDelmicATC Foyer13 05 15 35Practical session CSession 1 on Fundamentals in analyzing macromolecular heterogeneity in RELIONSebastian Eustermann EMBL Heidelberg GermanyKelly Nguyen MRC Laboratory of Molecular Biology United KingdomSession 2 on Advanced cryoEM single particle analysis cyroSPARC SPA topicDominik Hreb k Max Planck Institute of Biochemistry GermanyDavide Torre Max Planck Institute of Biochemistry GermanySession 3 on Advanced cryoET subtomogram averaging Relion Tomo topicTanmay Bharat MRC Laboratory of Molecular Biology United KingdomEuan Pyle EMBL Heidelberg GermanyBogdan Toader MRC Laboratory of Molecular Biology United KingdomSession 4 on Advanced cryoET subtomogram averaging WARP M Tomo topicMax Dreimann EMBL Heidelberg GermanyHigor Rosa EMBL Heidelberg GermanyDimitry Tegunov Genentech USASession 5 on Model building refinement and validationArjen Jakobi Delft University of Technology NetherlandsSession 1 Courtyard RoomsSession 2 Flex Lab BSession3 Flex Lab ASession 4 Computer Training LabSession 5 Helix A Seminar Room15 35 16 05Coffee breakCourtyard Room A B16 05 18 35Practical session DSession 1 on Fundamentals in analyzing macromolecular heterogeneity in RELIONSebastian Eustermann EMBL Heidelberg GermanyDari Kimanius Chan Zuckerberg Institute for Advanced Biological Imaging USA Virtual trainer Kelly Nguyen MRC Laboratory of Molecular Biology United KingdomSession 2 on Advanced cryoEM single particle analysis cyroSPARC SPA topicDominik Hreb k Max Planck Institute of Biochemistry GermanyDavide Torre Max Planck Institute of Biochemistry GermanySession 3 on Advanced cryoET subtomogram averaging Relion Tomo topicTanmay Bharat MRC Laboratory of Molecular Biology United KingdomEuan Pyle EMBL Heidelberg GermanyBogdan Toader MRC Laboratory of Molecular Biology United KingdomSession 4 on Advanced cryoET subtomogram averaging WARP M Tomo topicMax Dreimann EMBL Heidelberg GermanyHigor Rosa EMBL Heidelberg GermanyDimitry Tegunov Genentech USASession 5 on Model building refinement and validationArjen Jakobi Delft University of Technology NetherlandsSession 1 Courtyard RoomsSession 2 Flex Lab BSession3 Flex Lab ASession 4 Computer Training LabSession 5 Helix A Seminar Room18 35 19 35Pizza dinnerATC Rooftop Lounge19 35 20 35Poster session 1Helix A20 35Bus to hotel Day 5 Friday 21 August 2026 Time Europe Berlin SessionLocation08 20 08 30Bus from hotel to EMBL ATC Entrance08 30 08 35Overview of the day08 35 09 50Lecture Next generation atomic model building refinement and validationArjen Jakobi Delft University of Technology The NetherlandsCourtyard Room A B09 50 11 05Lecture Next generation integrative model buildingJan Kosinski EMBL Hamburg GermanyCourtyard Room A B11 05 11 35Coffee breakCourtyard Room A B11 35 12 50EMDB and EMPIAR data repositoriesMatthew Hartley EMBL EBI United Kingdom virtual speaker Kyle Morris EMBL EBI United Kingdom virtual speaker Courtyard Room A B12 50 13 50Technology Lunchsponsored byCEOS Corrected Electron Optical SystemsLeica MicrosystemsATC Foyer13 50 14 20Panel discussion Validation and FAIR dataPanel leaders Sebastian Eustermann EMBL Heidelberg Germany and Kelly Nguyen MRC Laboratory of Molecular Biology United KingdomCourtyard Room A B13 50 16 20Practical session ESession 1 on Fundamentals in analyzing macromolecular heterogeneity in RELIONSebastian Eustermann EMBL Heidelberg GermanyKelly Nguyen MRC Laboratory of Molecular Biology United KingdomSession 2 on Advanced cryoEM single particle analysis cyroSPARC SPA topicDominik Hreb k Max Planck Institute of Biochemistry GermanyDavide Torre Max Planck Institute of Biochemistry GermanySession 3 on Advanced cryoET subtomogram averaging Relion Tomo topicTanmay Bharat MRC Laboratory of Molecular Biology United KingdomEuan Pyle EMBL Heidelberg GermanyBogdan Toader MRC Laboratory of Molecular Biology United KingdomSession 4 on Advanced cryoET subtomogram averaging WARP M Tomo topicMax Dreimann EMBL Heidelberg GermanyHigor Rosa EMBL Heidelberg GermanyDimitry Tegunov Genentech USASession 5 on Model building refinement and validationArjen Jakobi Delft University of Technology NetherlandsSession 6 on 2D template matchingJohannes Elferich University of Massachusetts Medical School USANikolaus Grigorieff University of Massachusetts Medical School USASession 1 Courtyard RoomsSession 2 Flex Lab BSession3 Flex Lab ASession 4 Computer Training LabSession 5 Helix A Seminar RoomSession 6 Helix B Seminar Room16 20 16 50Coffee breakCourtyard Room A B16 50 18 20Practical session FSession 1 on Fundamentals in analyzing macromolecular heterogeneity in RELIONSebastian Eustermann EMBL Heidelberg GermanyDari Kimanius Chan Zuckerberg Institute for Advanced Biological Imaging USA Virtual trainer Kelly Nguyen MRC Laboratory of Molecular Biology United KingdomSession 2 on Advanced cryoEM single particle analysis cyroSPARC SPA topicDominik Hreb k Max Planck Institute of Biochemistry GermanyDavide Torre Max Planck Institute of Biochemistry GermanySession 3 on Advanced cryoET subtomogram averaging Relion Tomo topicTanmay Bharat MRC Laboratory of Molecular Biology United KingdomEuan Pyle EMBL Heidelberg GermanyBogdan Toader MRC Laboratory of Molecular Biology United KingdomSession 4 on Advanced cryoET subtomogram averaging WARP M Tomo topicMax Dreimann EMBL Heidelberg GermanyHigor Rosa EMBL Heidelberg GermanyDimitry Tegunov Genentech USASession 5 on Model building refinement and validationArjen Jakobi Delft University of Technology NetherlandsSession 6 on 2D template matchingJohannes Elferich University of Massachusetts Medical School USANikolaus Grigorieff University of Massachusetts Medical School USASession 1 Courtyard RoomsSession 2 Flex Lab BSession3 Flex Lab ASession 4 Computer Training LabSession 5 Helix A Seminar RoomSession 6 Helix B Seminar Room18 20 19 35Lecture Next generation 2D template matching and beyondNikolaus Grigorieff University of Massachusetts Medical School USACourtyard Room A B19 35 20 35Tapas dinnerATC Rooftop Lounge20 35 21 35Poster session 2Helix A21 35Bus to hotel Day 6 Saturday 22 August 2026 Time Europe Berlin SessionLocation08 55 09 05Bus from hotel to EMBL ATC Entrance09 05 09 10Overview of the day09 10 10 25Lecture High throughput and resolution data collectionSonja Welsch Max Planck Institute of Biophysics GermanyCourtyard Room A B10 25 11 40Lecture Correlative light and electron microscopy for structural cell biologyWanda Kukulski University of Bern SwitzerlandCourtyard Room A B11 40 12 10Coffee breakCourtyard Room A B12 10 12 40Panel discussion Data acquisitionPanel leader Simone Mattei EMBL Heidelberg GermanyCourtyard Room A B12 40 13 40Lunch breakEMBL Canteen13 40 16 10Practical session GSession 1 on Fundamentals in analyzing macromolecular heterogeneity in RELIONSebastian Eustermann EMBL Heidelberg GermanyKelly Nguyen MRC Laboratory of Molecular Biology United KingdomSession 2 on Advanced cryoEM single particle analysis cyroSPARC SPA topicDominik Hreb k Max Planck Institute of Biochemistry GermanyDavide Torre Max Planck Institute of Biochemistry GermanySession 3 on Advanced cryoET subtomogram averaging Relion Tomo topicTanmay Bharat MRC Laboratory of Molecular Biology United KingdomEuan Pyle EMBL Heidelberg GermanyBogdan Toader MRC Laboratory of Molecular Biology United KingdomSession 4 on Advanced cryoET subtomogram averaging WARP M Tomo topicMax Dreimann EMBL Heidelberg GermanyHigor Rosa EMBL Heidelberg GermanyDimitry Tegunov Genentech USASession 5 on Model building refinement and validationArjen Jakobi Delft University of Technology NetherlandsSession 6 on 2D template matchingJohannes Elferich University of Massachusetts Medical School USANikolaus Grigorieff University of Massachusetts Medical School USASession 1 Courtyard RoomsSession 2 Flex Lab BSession3 Flex Lab ASession 4 Computer Training LabSession 5 Helix A Seminar RoomSession 6 Helix B Seminar Room16 10 16 40Coffee breakCourtyard Room A B16 40 19 10Practical session HSession 1 on Fundamentals in analyzing macromolecular heterogeneity in RELIONSebastian Eustermann EMBL Heidelberg GermanyDari Kimanius Chan Zuckerberg Institute for Advanced Biological Imaging USA Virtual trainer Kelly Nguyen MRC Laboratory of Molecular Biology United KingdomSession 2 on Advanced cryoEM single particle analysis cyroSPARC SPA topicDominik Hreb k Max Planck Institute of Biochemistry GermanyDavide Torre Max Planck Institute of Biochemistry GermanySession 3 on Advanced cryoET subtomogram averaging Relion Tomo topicTanmay Bharat MRC Laboratory of Molecular Biology United KingdomEuan Pyle EMBL Heidelberg GermanyBogdan Toader MRC Laboratory of Molecular Biology United KingdomSession 4 on Advanced cryoET subtomogram averaging WARP M Tomo topicMax Dreimann EMBL Heidelberg GermanyHigor Rosa EMBL Heidelberg GermanyDimitry Tegunov Genentech USASession 5 on Model building refinement and validationArjen Jakobi Delft University of Technology NetherlandsSession 6 on 2D template matchingJohannes Elferich University of Massachusetts Medical School USANikolaus Grigorieff University of Massachusetts Medical School USASession 1 Courtyard RoomsSession 2 Flex Lab BSession3 Flex Lab ASession 4 Computer Training LabSession 5 Helix A Seminar RoomSession 6 Helix B Seminar Room19 10 20 10DinnerEMBL Canteen20 10 20 55Lecture cryoEM careers in academia and pharmaAlexis Rohou Genentech USA Virtual speaker Courtyard Room A B20 55 21 40Discussion round Career pathsATC Rooftop Lounge21 40Bus to hotel Day 7 Sunday 23 August 2026 Time Europe Berlin SessionLocation08 55 09 05Bus from hotel to EMBL ATC Entrance09 05 09 10Overview of the dayCourtyard Room A B09 10 11 10Practical Session I Drop in sessionSession 1 on Fundamentals in analyzing macromolecular heterogeneity in RELIONSebastian Eustermann EMBL Heidelberg GermanyKelly Nguyen MRC Laboratory of Molecular Biology United KingdomSession 2 on Advanced cryoEM single particle analysis cyroSPARC SPA topicDominik Hreb k Max Planck Institute of Biochemistry GermanyDavide Torre Max Planck Institute of Biochemistry GermanySession 3 on Advanced cryoET subtomogram averaging Relion Tomo topicTanmay Bharat MRC Laboratory of Molecular Biology United KingdomEuan Pyle EMBL Heidelberg GermanyBogdan Toader MRC Laboratory of Molecular Biology United KingdomSession 4 on Advanced cryoET subtomogram averaging WARP M Tomo topicMax Dreimann EMBL Heidelberg GermanyHigor Rosa EMBL Heidelberg GermanyDimitry Tegunov Genentech USASession 5 on Model building refinement and validationArjen Jakobi Delft University of Technology NetherlandsSession 6 on 2D template matchingJohannes Elferich University of Massachusetts Medical School USANikolaus Grigorieff University of Massachusetts Medical School USASession 7 on Cryo TEMSimon Fromm EMBL Heidelberg GermanySession 8 on Cryo LMZhengyi Yang EMBL Heidelberg GermanySession 9 on HPF Waffle prepGeorg Wolff EMBL Heidelberg GermanySession 10 on FIB SEMAnastasiia Babenko EMBL Heidelberg GermanySession 1 Courtyard RoomsSession 2 Flex Lab BSession3 Flex Lab ASession 4 Computer Training LabSession 5 Helix A Seminar RoomSession 6 Helix B Seminar RoomSession 7 8 9 10 Imaging Center11 10 11 40Coffee breakEMBL Canteen11 40 13 40Practical Session J Drop in sessionSession 1 on Fundamentals in analyzing macromolecular heterogeneity in RELIONSebastian Eustermann EMBL Heidelberg GermanyKelly Nguyen MRC Laboratory of Molecular Biology United KingdomSession 2 on Advanced cryoEM single particle analysis cyroSPARC SPA topicDominik Hreb k Max Planck Institute of Biochemistry GermanyDavide Torre Max Planck Institute of Biochemistry GermanySession 3 on Advanced cryoET subtomogram averaging Relion Tomo topicTanmay Bharat MRC Laboratory of Molecular Biology United KingdomEuan Pyle EMBL Heidelberg GermanyBogdan Toader MRC Laboratory of Molecular Biology United KingdomSession 4 on Advanced cryoET subtomogram averaging WARP M Tomo topicMax Dreimann EMBL Heidelberg GermanyHigor Rosa EMBL Heidelberg GermanyDimitry Tegunov Genentech USASession 5 on Model building refinement and validationArjen Jakobi Delft University of Technology NetherlandsSession 6 on 2D template matchingJohannes Elferich University of Massachusetts Medical School USANikolaus Grigorieff University of Massachusetts Medical School USASession 7 on Cryo TEMSimon Fromm EMBL Heidelberg GermanySession 8 on Cryo LMZhengyi Yang EMBL Heidelberg GermanySession 9 on HPF Waffle prepGeorg Wolff EMBL Heidelberg GermanySession 10 on FIB SEMAnastasiia Babenko EMBL Heidelberg GermanySession 1 Courtyard RoomsSession 2 Flex Lab BSession3 Flex Lab ASession 4 Computer Training LabSession 5 Helix A Seminar RoomSession 6 Helix B Seminar RoomSession 7 8 9 10 Imaging Center13 40 14 40Lunch breakCourtyard Room A B14 40 16 40Practical Session K Drop in sessionSession 1 on Fundamentals in analyzing macromolecular heterogeneity in RELIONSebastian Eustermann EMBL Heidelberg GermanyKelly Nguyen MRC Laboratory of Molecular Biology United KingdomSession 2 on Advanced cryoEM single particle analysis cyroSPARC SPA topicDominik Hreb k Max Planck Institute of Biochemistry GermanyDavide Torre Max Planck Institute of Biochemistry GermanySession 3 on Advanced cryoET subtomogram averaging Relion Tomo topicTanmay Bharat MRC Laboratory of Molecular Biology United KingdomEuan Pyle EMBL Heidelberg GermanyBogdan Toader MRC Laboratory of Molecular Biology United KingdomSession 4 on Advanced cryoET subtomogram averaging WARP M Tomo topicMax Dreimann EMBL Heidelberg GermanyHigor Rosa EMBL Heidelberg GermanyDimitry Tegunov Genentech USASession 5 on Model building refinement and validationArjen Jakobi Delft University of Technology NetherlandsSession 6 on 2D template matchingJohannes Elferich University of Massachusetts Medical School USANikolaus Grigorieff University of Massachusetts Medical School USASession 7 on Cryo TEMSimon Fromm EMBL Heidelberg GermanySession 8 on Cryo LMZhengyi Yang EMBL Heidelberg GermanySession 9 on HPF Waffle prepGeorg Wolff EMBL Heidelberg GermanySession 10 on FIB SEMAnastasiia Babenko EMBL Heidelberg GermanySession 1 Courtyard RoomsSession 2 Flex Lab BSession3 Flex Lab ASession 4 Computer Training LabSession 5 Helix A Seminar RoomSession 6 Helix B Seminar RoomSession 7 8 9 10 Imaging Center16 40 18 40Bus to downtown and free time18 40 20 40Downtown dinnerKulturbrauerei Heidelberg Day 8 Monday 24 August 2026 Time Europe Berlin SessionLocation08 50 09 00Bus from hotel to EMBL ATC Entrance09 00 09 05Overview of the dayCourtyard Room A B09 05 10 20Lecture Hot topics in cryo ETSvetlana Dodonova EMBL Heidelberg GermanyCourtyard Room A B10 20 12 20Practical Session L Drop in sessionSession 1 on Fundamentals in analyzing macromolecular heterogeneity in RELIONSebastian Eustermann EMBL Heidelberg GermanyKelly Nguyen MRC Laboratory of Molecular Biology United KingdomSession 2 on Advanced cryoEM single particle analysis cyroSPARC SPA topicDominik Hreb k Max Planck Institute of Biochemistry GermanyDavide Torre Max Planck Institute of Biochemistry GermanySession 3 on Advanced cryoET subtomogram averaging Relion Tomo topicTanmay Bharat MRC Laboratory of Molecular Biology United KingdomEuan Pyle EMBL Heidelberg GermanyBogdan Toader MRC Laboratory of Molecular Biology United KingdomSession 4 on Advanced cryoET subtomogram averaging WARP M Tomo topicMax Dreimann EMBL Heidelberg GermanyHigor Rosa EMBL Heidelberg GermanyDimitry Tegunov Genentech USASession 5 on Model building refinement and validationArjen Jakobi Delft University of Technology NetherlandsSession 6 on 2D template matchingJohannes Elferich University of Massachusetts Medical School USANikolaus Grigorieff University of Massachusetts Medical School USASession 7 on Cryo TEMSimon Fromm EMBL Heidelberg GermanySession 8 on Cryo LMZhengyi Yang EMBL Heidelberg GermanySession 9 on HPF Waffle prepGeorg Wolff EMBL Heidelberg GermanySession 10 on FIB SEMAnastasiia Babenko EMBL Heidelberg GermanySession 1 Courtyard RoomsSession 2 Flex Lab BSession3 Flex Lab ASession 4 Computer Training LabSession 5 Helix A Seminar RoomSession 6 Helix B Seminar RoomSession 7 8 9 10 Imaging Center12 20 13 20Lunch breakEMBL Canteen13 20 15 20Practical Session M Drop in sessionSession 1 on Fundamentals in analyzing macromolecular heterogeneity in RELIONSebastian Eustermann EMBL Heidelberg GermanyKelly Nguyen MRC Laboratory of Molecular Biology United KingdomSession 2 on Advanced cryoEM single particle analysis cyroSPARC SPA topicDominik Hreb k Max Planck Institute of Biochemistry GermanyDavide Torre Max Planck Institute of Biochemistry GermanySession 3 on Advanced cryoET subtomogram averaging Relion Tomo topicTanmay Bharat MRC Laboratory of Molecular Biology United KingdomEuan Pyle EMBL Heidelberg GermanyBogdan Toader MRC Laboratory of Molecular Biology United KingdomSession 4 on Advanced cryoET subtomogram averaging WARP M Tomo topicMax Dreimann EMBL Heidelberg GermanyHigor Rosa EMBL Heidelberg GermanyDimitry Tegunov Genentech USASession 5 on Model building refinement and validationArjen Jakobi Delft University of Technology NetherlandsSession 6 on 2D template matchingJohannes Elferich University of Massachusetts Medical School USANikolaus Grigorieff University of Massachusetts Medical School USASession 7 on Cryo TEMSimon Fromm EMBL Heidelberg GermanySession 8 on Cryo LMZhengyi Yang EMBL Heidelberg GermanySession 9 on HPF Waffle prepGeorg Wolff EMBL Heidelberg GermanySession 10 on FIB SEMAnastasiia Babenko EMBL Heidelberg GermanySession 1 Courtyard RoomsSession 2 Flex Lab BSession3 Flex Lab ASession 4 Computer Training LabSession 5 Helix A Seminar RoomSession 6 Helix B Seminar RoomSession 7 8 9 10 Imaging Center15 20 15 50Coffee breakCourtyard Room A B15 50 17 50Practical Session N Drop in sessionSession 1 on Fundamentals in analyzing macromolecular heterogeneity in RELIONSebastian Eustermann EMBL Heidelberg GermanyKelly Nguyen MRC Laboratory of Molecular Biology United KingdomSession 2 on Advanced cryoEM single particle analysis cyroSPARC SPA topicDominik Hreb k Max Planck Institute of Biochemistry GermanyDavide Torre Max Planck Institute of Biochemistry GermanySession 3 on Advanced cryoET subtomogram averaging Relion Tomo topicTanmay Bharat MRC Laboratory of Molecular Biology United KingdomEuan Pyle EMBL Heidelberg GermanyBogdan Toader MRC Laboratory of Molecular Biology United KingdomSession 4 on Advanced cryoET subtomogram averaging WARP M Tomo topicMax Dreimann EMBL Heidelberg GermanyHigor Rosa EMBL Heidelberg GermanyDimitry Tegunov Genentech USASession 5 on Model building refinement and validationArjen Jakobi Delft University of Technology NetherlandsSession 6 on 2D template matchingJohannes Elferich University of Massachusetts Medical School USANikolaus Grigorieff University of Massachusetts Medical School USASession 7 on Cryo TEMSimon Fromm EMBL Heidelberg GermanySession 8 on Cryo LMZhengyi Yang EMBL Heidelberg GermanySession 9 on HPF Waffle prepGeorg Wolff EMBL Heidelberg GermanySession 10 on FIB SEMAnastasiia Babenko EMBL Heidelberg GermanySession 1 Courtyard RoomsSession 2 Flex Lab BSession3 Flex Lab ASession 4 Computer Training LabSession 5 Helix A Seminar RoomSession 6 Helix B Seminar RoomSession 7 8 9 10 Imaging Center17 50 19 05Poster session All participants Helix A19 05 20 05DinnerEMBL Canteen20 05Bus to hotel Day 9 Tuesday 25 August 2026 Time Europe Berlin SessionLocation08 30 08 40Bus from hotel to EMBL ATC Entrance08 40 08 45Overview of the dayCourtyard Room A B08 45 10 00Lecture Hot topics cryoEMCristina Paulino Heidelberg University GermanyCourtyard Room A B10 00 10 30Coffee breakCourtyard Room A B10 30 11 45Lecture To be confirmedKiarash Jamali MRC Laboratory of Molecular Biology United KingdomCourtyard Room A B11 45 12 15Wrap up practicals highlights presented by participantsCourtyard Room A B12 15 13 15Final panel discussion Wrap up with emphasis on the future of cryoEM responsible practice reporting and validation standardsCourtyard Room A B13 15 13 30Packed lunch and departureCourtyard Room A B13 30Bus to hotel and main train station Practical information Registration fees The course is limited to 24 participants For selection purposes please note that your application will not be considered without a letter of motivation Registration fees Your registration for the event includes Admission to the event Meals and coffee breaks Course materials Access to the e learning platform A letter to support your visa application for more information check the Travel and accommodation tab For this EMBO course the fees include accommodation twin room and transportation to and from the ISG Hotel to the venue Academia 550PhD Student 550Industry 1100 Confirmation and payment The registration fee should be paid only after acceptance to the course The results will be announced approximately 2 3 weeks after the application deadline Cancellation policy If you are no longer able to take part in the course please inform your course contact responsible for this event Your registration and the submitted motivation letter will be deleted Please also check our Terms and Conditions for the cancellation policy Submitting a motivation letter After you have logged in and successfully registered you will receive an email asking you to submit your motivation letter Click on the link provided and enter your motivation letter in the text box provided Alternatively you can submit your motivation letter by clicking on the link on the confirmation page directly after registering Instructions Include your relevant skills experience and qualifications showing why you would be suitable for the course Explain why you would like to attend including what you can contribute and how you think you will benefit from the course Please note The limit of 2 000 characters refers to manually typed text and 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Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Travel grant The travel grant will cover the cost of travel airfare train bus taxi and visa and or registration fees and is provided up to specified caps which are normally as follows up to 500 for any participant travelling to an EMBO Practical Course up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Practical Course The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grants There is the possibility to apply for a childcare grant to offset child care costs incurred by participants speakers trainers and organisers when attending a course Eligible costs include but are not limited to fees for a babysitter child care facility or travel costs for a caregiver Please note that priority will be given to early stage researchers There is a limited amount of funding available for the childcare grants and funds will be distributed amongst eligible applicants Boehringer Ingelheim Fonds travel grant Applies to selected courses only Availability will be indicated during the abstract or motivation letter submission process This grant covers costs related to your attendance to the course registration travel and accommodation costs The grant is restricted to PhD students and postdocs who conduct basic biomedical research Whether you are eligible to apply for a travel grant depends on when you received your university entrance qualification e g Abitur A Levels High School Diploma Final State Examination for PhD and MD students as well as graduates the university entrance qualification must not have been obtained more than 11 years ago at the time of the envisaged course for postdocs the university entrance qualification must not have been obtained more than 13 years ago at the time of the envisaged course EMBO accessibility grant For EMBO Practical Course participants with accessibility needs there is the possibility to apply for an accessibility grant to offset costs incurred by participants or speakers when participating at a course Eligible costs include costs incurred for equipment or adaptations to the course environment or travel costs for an event companion to assist the participant or speaker during the course where necessary While we do our best to accommodate needs please note that extensive changes to the course environment might not be possible Priority will be given to early stage researchers A maximum amount of 500 can be awarded per participant applying for an EMBO accessibility grant In order to apply for this grant for EMBO Practical Courses you must be registered by the application deadline Application Whether you are attending onsite or virtually to apply for financial assistance please follow the steps in the application system During the process of submitting your motivation letter to the system you will be asked which type of grant you want to apply for Applications for financial support will not affect the outcome of your selection results Information about the grant will be sent out shortly after the motivation letter deadline Results Grant allocations are announced by email to all applicants after the selection results Allocation results do not impact your selection to the course Selection for financial assistance is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Please note that for childcare grants priority will be given to early stage researchers Further details Check out this list of external funding opportunities For further information about financial assistance please refer to the FAQ page Participant selection The selection results will be announced by email to all applicants We aim to announce 3 weeks 21 days after the motivation letter submission deadline but delays may occur Travel and accommodation Visa We can send you a registration confirmation to support your visa procedure not an official invitation letter Please contact the Conference Officer responsible for your event Read our FAQ for more information Travel If you are travelling to Heidelberg via aeroplane train car or long distance bus you can find useful information on our travel information page Accommodation Accommodation in twin rooms with breakfast included in the registration fee Accommodation will be booked for the selected participants at ISG Hotel for the default dates of 16 to 25 August 2026 8 nights In case you would like to have a single room please let the hotel know and please note that you will be required to pay a surcharge per night availability of single rooms may be limited This should be paid by you directly to the Hotel during your stay We recommend that all course participants stay at the ISG Hotel for the course Local transportation Course shuttle buses Shuttle buses will go from the ISG Hotel to EMBL and back mornings and evenings A bus schedule and location of the bus stops will be made available prior to the meeting Other local transportation In addition to the shuttle busses there is also the public bus 28 that serves the EMBL campus and taxis can be easily booked at any time For more information please refer to the local transportation RNV website You may also walk from the ISG Hotel to EMBL takes up to 30 minutes Map to walk from ISG Hotel to EMBL Further details Address EMBL Heidelberg Meyerhofstra e 1 69117 Heidelberg Germany For more information about accommodation and travel please refer to the FAQ page On site information Here you will find useful information for when you are onsite at the event Catering All meals and coffee breaks are included in the registration fee Our catering staff will prepare a variety of vegetarian meals meat and fish dishes soups pasta fresh fruit and vegetables as well as a variety of desserts Please wear your badge at all times when serving yourself No food or drinks are allowed in the laboratories Internet Wi Fi is available on campus using the EMBL Events network and the event specific password which will be provided on site The eduroam network secure worldwide roaming access service developed for the international research and education community is also available Photography During the course a member of the Marketing Team may be taking photos If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Charging stations There are lockers available next to the stairs leading down into the Auditorium You will find some of those equipped with sockets to charge your smartphone tablet etc In most places the electricity is 220 volts AC 50 cycles An adaptor and a plug that fits the German socket may be needed for your appliances laptop i e American Japanese etc Printing We can help to print your boarding pass train ticket Please send it to events embl de and collect your print outs at the registration desk Luggage There are lockers available on site to store your luggage which require a 2 EURO coin to operate There is another luggage room on level E0 which is free to use but remains unlocked during the course Lost and found Lost and Found items are kept at the main reception Nursing room There is a nursing room available in the ATC Rooftop Lounge on level A29 Room for prayers meditation and yoga There is a room for prayer yoga and meditation located on level E0 behind the Auditorium Please be respectful of others using the room EMBL campus map Health and safety notes Please take a moment to read our health and safety policy Do not smoke in any EMBL building Eating and drinking is prohibited in the Auditorium and all laboratories Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required The first aid room is located next to the ATC Registration Desk room 10 205 Dial the Emergency number 222 from any EMBL internal phone only Be prepared to answer the following questions Where is the accident What happened How many injured Emergency number 06221 387 7821 from mobile phones Please report all accidents to the conference officer at the registration desk In case of fire Press the nearest fire alarm button or the Emergency number 222 from any internal phone A loud fire alarm will go off if an evacuation is required On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting points Do not use the lifts Beyond first aid The Heidelberg University Hospital or Universit tsklinikum has a 24 hour accident and emergency facility and is at Im Neuenheimer Feld 672 It is a 8km or a 20 minute taxi ride away from EMBL In a medical emergency the ambulance service generally transports patients to this hospital Please remember to bring your own medication if needed to the conference Note that the next pharmacy is a 4 minute drive from the EMBL but for many medications you will be required to see a doctor to get a prescription Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg The EMBL course and conference office team are able to advise you on where to turn for emergency or non emergency medical treatment in Heidelberg and can assist you in making appointments and or arranging transport to get to the pharmacy or a doctor of your choice if necessary Please note we are not however permitted to personally accompany you off campus Sightseeing A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing Technical requirements and event software delete if no technical requirements for this course Technical requirements Below you will find the software and technical requirements for this course You will need admin rights to be able to install the software on your computer and we recommend you try this before the course If you do not have admin rights please contact your technical support team in advance to make sure the software can be installed Additional software The EMBL eCampus learning platform will be used to collaborate communicate and network with all of the course participants All participants will receive information on how to join shortly before the course We recommend using Chrome Safari or Mozilla Firefox browsers for eCampus Zoom will be used for the live talks and Q A sessions More information will be provided closer to the start of the course Other information While using the software during the course please make sure you have nothing else using your bandwidth We recommend using a wired connection Additional information Please find additional information including FAQs and terms and conditions on our Information for Participants page Sponsors Event sponsors Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other events or contact sponsorship embl org for further information Request a sponsorship brochure Warning EMBL advises sponsors to beware of fraudulent schemes falsely offering sponsorship opportunities All legitimate communication about sponsorship for EMBL conferences symposia and courses comes directly from EMBL via official EMBL email accounts EMBL does not use third parties for sponsorship acquisition EMBL does not sell attendee lists EMBL will never ask for credit card details or direct payments All payments are processed by invoice only If you receive a suspicious message claiming to be from or on behalf of EMBL please report it to sponsorship embl org Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1350 Social 1600 900 PPT Slide 16 9... OverviewSpeakersPreliminary programmePractical informationSponsorsMedia kit Overview Course overview Over the past decade, cryo-electron microscopy has transformed our understanding of biomolecular structures across multiple spatial scales from atoms to cells. Technological advances have provided unprecedented insights, from atomic-resolution structures of biologically heterogeneous states to the first glimpses into the molecular sociology of a cell. Yet, emerging breakthroughs, such as time-resolved approaches, novel (correlated) imaging technologies, and AI-driven image processing, highlight the potential of cryo-EM for another leap forward. To realise this potential, in-depth advanced training is essential for driving innovation and developing new technologies to tackle emerging biological challenges. This course offers a comprehensive foundation in advanced single-particle and...
EMBO Practical Course
EMBL Heidelberg
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