EMBL Events

EMBL delivers world-class courses, conferences and workshops at the forefront of molecular life science and its applications.

Browse upcoming events below, or learn more about training at EMBL.

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27 February - 1 March 2024

Integrative analysis of multi-omics data

27 February 20242024CourseEMBL Heidelberg

Wolfgang Huber, Oliver Stegle, Britta Velten

OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview Course overview Biological and biomedical research is increasingly driven by assays that measure multiple omics data types multi omics at single cell resolution and or with spatial resolution transcriptome proteome genomic variants epigenetic marks metabolome functional assays imaging Joint... OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview Course overview Biological and biomedical research is increasingly driven by assays that measure multiple ‘omics data types (“multi-omics”), at single cell resolution, and/or with spatial resolution: transcriptome, proteome, genomic variants, epigenetic marks, metabolome, functional assays, imaging. Joint mathematical-computational modeling, mechanistic and integrated statistical analysis of such data is an urgent need – one of the major analytical challenges scientists face today. How to discover the important underlying patterns, categories or trends, and to arrive at statistically robust conclusions using explainable models of reasoning? The course’s core objective is to convey conceptual and mathematical foundations that underpin existing and emerging integrative multimodal data strategies and practical...

EMBO Practical Course

EMBL Heidelberg

Registration
Closed

29 February 2024

UniProt for proteomics scientists

29 February 20242024WebinarVirtual

UniProt is a comprehensive expert led publicly available database of protein sequence function and variation information This webinar will give a brief introduction to the UniProt website and then highlight resources available that proteomics scientists or users with large protein datasets may find useful in analysing their data This will encompass our proteomes service how to convert and retrieve ID mappings how to carry out a peptide search and how to visualise new large scale proteomics derived PTM data The webinar will then go on to introduce the UniProt Proteins API which allows researchers to access and download UniProt data alongside large scale genomic proteomics and variation data without needing prior in depth knowledge of programmatic languages Data is available for download and querying in a range of formats including XML FASTA and PEFF The API multi query search functions will be demonstrated and useful features such as searching the database by peptide finding proteomic evidence of post translational modifications and accessing a protein entry to find its peptides will be explained The UniProt Proteins API is available at www ebi ac uk proteins api doc... UniProt is a comprehensive, expert-led, publicly available database of protein sequence, function, and variation information.This webinar will give a brief introduction to the UniProt website and then highlight resources available that proteomics scientists or users with large protein datasets may find useful in analysing their data. This will encompass our proteomes service, how to convert and retrieve ID mappings, how to carry out a peptide search and how to visualise new large scale proteomics-derived PTM data.The webinar will then go on to introduce the UniProt Proteins API which allows researchers to access and download UniProt data alongside large-scale genomic, proteomics and variation data without needing prior in-depth knowledge of programmatic languages. Data is available for download and querying in a range of formats, including XML, FASTA, and PEFF. The API multi-query search...

Webinar

Virtual


4 March - 8 March 2024

Introduction to multi-omics data integration and visualisation

4 March 20242024CourseEMBL-EBI

Meredith Willmott

With the increase in the volume of data across the whole spectrum of biology more opportunities as well as challenges have been created to identify novel perspectives and answer questions in life sciences This may also include public domain data which can provide added value to data derived through researcher s own work and inform experimental design This introductory course will highlight the challenges that researchers face in integrating multi omics data sets using biological examples The course will focus on the use of public data resources and open access tools for enabling integrated working with an emphasis on data visualisation This course will not include systems biology modelling or machine learning A major element of this course is a group project where participants will be placed in small groups to work together on a challenge set by trainers from EMBL EBI data resource and research teams This allows people to explore the bioinformatics tools and resources introduced in the course and to apply these to a set problem providing hands on experience of relevance to their own research The group work will culminate in a presentation session involving all participants on the final day of the course giving an opportunity for wider discussion on the benefits and challenges of integrating data You may refer to the previous group projects that were organised for this course in March 2023... With the increase in the volume of data across the whole spectrum of biology, more opportunities as well as challenges have been created to identify novel perspectives and answer questions in life sciences. This may also include public domain data, which can provide added value to data derived through researcher’s own work and inform experimental design. This introductory course will highlight the challenges that researchers face in integrating multi-omics data sets using biological examples. The course will focus on the use of public data resources and open access tools for enabling integrated working, with an emphasis on data visualisation. This course will not include systems biology modelling or machine learning.A major element of this course is a group project, where participants will be placed in small groups to work together on a challenge set by trainers from EMBL-EBI data...

Course

EMBL-EBI

Registration
Closed

4 March - 8 March 2024

Gene expression at spatial resolution

4 March 20242024CourseEMBL Heidelberg

Vladimir Benes, Dirk Jürgensen, Elisabeth Zielonka

OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview Course overview This interactive course will introduce participants to a new generation of a spatially resolved transcriptomics assay provided by 10x Genomics Objectives The Visium Cytassist Spatial Gene Expression Solution uses probes targeting the whole transcriptome for intact tissue sections in morphological... OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview Course overview This interactive course will introduce participants to a new generation of a spatially resolved transcriptomics assay provided by 10x Genomics. Objectives The Visium Cytassist Spatial Gene Expression Solution uses probes targeting the whole transcriptome for intact tissue sections in morphological context, offering a previously inaccessible view of tissue biology. These two complementary methods to study tissue come together on Visium Cytassist Spatial Gene Expression slides. Through practical work in the lab and theoretical sessions, the participants will learn the entire workflow of sample preparation of fresh-frozen tissue samples, fixation and sequencing library preparation. Utilising the 10x Genomics Loupe Browser pipeline, the participants will also have hands-on training in spatial...

Course

EMBL Heidelberg

Registration
Closed

6 March 2024

Bioinformatic approaches to understand the role of the human microbiome in health and disease

6 March 20242024WebinarVirtual

The human microbiome represents a diverse community of microbes with important roles for the maintenance of human health The wealth of metagenomics data currently available has brought about a new era of research for the human microbiome field The ability to reconstruct high quality microbial genomes purely from metagenomic sequencing data has unlocked our ability to study the hidden microbial universe living alongside us Given there are thousands of human associated bacterial species that cannot yet be experimentally characterised there is a need to develop and apply bioinformatics methods to better understand their role in health and disease This webinar will provide an overview of current metagenomic approaches to study the human microbiome and introduce several statistical methods that can be used to link its composition and function to different human phenotypes and populations... The human microbiome represents a diverse community of microbes with important roles for the maintenance of human health. The wealth of metagenomics data currently available has brought about a new era of research for the human microbiome field. The ability to reconstruct high-quality microbial genomes purely from metagenomic sequencing data has unlocked our ability to study the hidden microbial universe living alongside us. Given there are thousands of human-associated bacterial species that cannot yet be experimentally characterised, there is a need to develop and apply bioinformatics methods to better understand their role in health and disease. This webinar will provide an overview of current metagenomic approaches to study the human microbiome and introduce several statistical methods that can be used to link its composition and function to different human phenotypes and...

Webinar

Virtual


11 March - 15 March 2024

Mathematics of life: modelling molecular mechanisms

11 March 20242024CourseVirtual

Juanita Riveros

This course will provide participants with an introduction and hands on training on modelling approaches tools and resources used in systems biology as well as touch on network analysis Computer models are increasingly used to understand the essential processes of biology Researchers in academic institutions as well as the pharmaceutical industry use mathematical models to generate hypotheses on how complex biomolecular systems work Modelling of biochemical pathways deregulated in disease conditions can offer mechanistic insights into the pathology help to elucidate mechanisms behind drug action and predict the dose required for treatment thus facilitating fundamental research and drug discovery This course will provide a helpful brief introduction to key modelling concepts and hands on training to use popular tools and resources used in this scientific field Virtual courseParticipants will learn via a mix of pre recorded lectures live presentations and trainer Q A sessions Practical experience will be developed through group activities and trainer led computational exercises Live sessions will be delivered using Zoom with additional support and asynchronous communication via Slack Pre recorded material may be provided before the course starts that participants will need to watch read or work through to gain the most out of the actual training event In the week before the course there will be a brief induction session Computational practicals will run on EMBL EBI s virtual training infrastructure meaning participants will not require access to a powerful computer or install complex software on their own machines Participants will need to be available between the hours of 09 00 17 30 GMT each day of the course Trainers will be available to assist answer questions and provide further explanations during these times... This course will provide participants with an introduction and hands-on training on modelling approaches, tools, and resources used in systems biology as well as touch on network analysis.Computer models are increasingly used to understand the essential processes of biology. Researchers in academic institutions as well as the pharmaceutical industry use mathematical models to generate hypotheses on how complex biomolecular systems work. Modelling of biochemical pathways deregulated in disease conditions can offer mechanistic insights into the pathology, help to elucidate mechanisms behind drug action, and predict the dose required for treatment thus facilitating fundamental research and drug discovery. This course will provide a helpful brief introduction to key modelling concepts and hands on training to use popular tools and resources used in this scientific field.Virtual...

Course

Virtual

Registration
Closed

12 March - 15 March 2024

AI and biology

12 March 20242024ConferenceEMBL Heidelberg, Virtual

Mohammed AlQuraishi, Wolfgang Huber, Anna Kreshuk, Emma Lundberg, Oliver Stegle

The aim of this symposium is to catalyse synergistic interactions between AI researchers in different subfields of biology by exploring shared theoretical approaches cross domain experiments and data integration as well as shared topics in dissemination of tools and collaboration with colleagues in experimental labs... OverviewSpeakersProgrammePractical informationSponsorsAboutMedia kit Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Symposium overview Artificial intelligence (AI) is transforming virtually all areas of science, and the life sciences are no exception. AI-based methods are pushing the limits of what is possible in experimental design, data analysis, simulation, and modelling. The aim of this symposium is to catalyse synergistic interactions between AI researchers in different subfields of biology by exploring shared theoretical approaches, cross-domain experiments, and data integration, as well as shared topics in dissemination of tools and collaboration with experimental labs. Furthermore, we will look into the future and discuss how the concerted actions of AI and life science communities can enable both fields to exploit the full...

EMBO | EMBL Symposium

EMBL Heidelberg, Virtual

Registration (Virtual)
05 March 2024
Registration (On-site)
Closed
Abstract submission
Closed

13 March 2024

Strain-resolved approaches for human microbiome studies

13 March 20242024WebinarVirtual

In the last few years the human microbiome has received great attention by the community due to its fundamental role in health and disease Advancements in the field have also been possible due to technological improvements in shotgun metagenomics including the development and application of computational approaches This webinar will introduce metagenomics for characterisation of the human microbiome with focus on computational tools to achieve strain level resolution This will comprise pipelines for generation of profiles as well as extraction of draft genomes It will also present some recent analyses aiming at conducting large scale scenario investigations including the use of machine learning approaches and the integration of human microbiomes with other sources... In the last few years, the human microbiome has received great attention by the community due to its fundamental role in health and disease. Advancements in the field have also been possible due to technological improvements in (shotgun) metagenomics, including the development and application of computational approaches.This webinar will introduce metagenomics for characterisation of the human microbiome with focus on computational tools to achieve strain-level resolution. This will comprise pipelines for generation of profiles as well as extraction of draft genomes. It will also present some recent analyses aiming at conducting large-scale scenario investigations, including the use of machine learning approaches and the integration of human microbiomes with other sources.

Webinar

Virtual


18 March - 22 March 2024

Livestock genomics

18 March 20242024CourseVirtual

Sophie Spencer

This hands on virtual course will introduce participants to methods and approaches for analysing genomic data from common livestock species including cattle pig chicken and sheep During the course participants will learn about the use of sequencing methods in the field of livestock genomics resequencing genomes locating variant data annotating genomes and carrying out GWAS approaches The course will also cover the use of public EMBL EBI resources such as Ensembl EVA and ENA to progress in your research as well as to submit and share your discoveries with the community and will present relevant use cases in the field The course will enable you to harness the wealth of publicly available farmed animal datasets held in EMBL EBI public archives and utilise our free services and tools to for example identify genetic variants associated with disease identify genetic markers associated with desirable breeding traits or use Ensembl Variant Effect Predictor VEP tool to predict the functional impact of genetic variants EMBL EBI is committed to support the livestock research community and industry to improve animal health and welfare increase productivity and reduce environmental impact Virtual courseParticipants will learn via a mix of pre recorded lectures live presentations and trainer led computational exercises Live sessions will be delivered using Zoom with additional support and asynchronous communication via Slack Pre recorded material may be provided before the course starts that participants will need to watch read or work through to gain the most out of the actual training event In the week before the course there will be a brief induction session Computational practicals will run on EMBL EBI s virtual training infrastructure meaning participants will not require access to a powerful computer or install complex software on their own machines Participants will need to be available during the course hours maximum 09 00 18 30 GMT each day of the course Trainers will be available to assist answer questions and provide further explanations during these times... This hands-on virtual course will introduce participants to methods and approaches for analysing genomic data from common livestock species, including cattle, pig, chicken, and sheep. During the course participants will learn about the use of sequencing methods in the field of livestock genomics, resequencing genomes, locating variant data, annotating genomes, and carrying out GWAS approaches. The course will also cover the use of public EMBL-EBI resources such as Ensembl, EVA, and ENA to progress in your research, as well as to submit and share your discoveries with the community, and will present relevant use cases in the field. The course will enable you to harness the wealth of publicly available farmed animal datasets held in EMBL-EBI public archives and utilise our free services and tools to for example, identify genetic variants associated with disease, identify...

Course

Virtual

Registration
Closed

19 March - 21 March 2024

Metabarcoding and data sharing for environmental DNA

19 March 20242024CourseVirtual

Ajay Mishra

This course will demonstrate applying metabarcoding analysis to eDNA for assessing biodiversity Sequencing DNA barcodes from mixed sources of DNA is being increasingly used to survey biodiversity whether analysing dietary content from faecal derived DNA or monitoring aquatic species from water derived DNA This course will give an overview of metabarcoding with different barcoding genes to target particular taxa Using an example data set we will go from raw sequence data through to assigning taxonomy to the sequence variants and some examples of downstream community analysis Sessions will comprise presentations and self paced computer practicals guided by an online interactive book containing theory and practice code This virtual course will be delivered via live streamed talks on Zoom with support from instructors via Zoom and Slack during the timetabled sessions Computer practicals will run on a virtual training platform so attendees will not need access to a powerful computer or to install any software We are willing to make reasonable adjustments to facilitate learning where possible and will provide clear routes to enable anyone that requires this to discuss this with us ahead of the training... This course will demonstrate applying metabarcoding analysis to eDNA for assessing biodiversity.Sequencing DNA barcodes from mixed sources of DNA is being increasingly used to survey biodiversity, whether analysing dietary content from faecal-derived DNA or monitoring aquatic species from water-derived DNA. This course will give an overview of metabarcoding with different barcoding genes to target particular taxa. Using an example data set we will go from raw sequence data through to assigning taxonomy to the sequence variants and some examples of downstream community analysis.Sessions will comprise presentations and self-paced computer practicals guided by an online interactive book containing theory and practice code.This virtual course will be delivered via live-streamed talks on Zoom with support from instructors via Zoom and Slack during the timetabled sessions. Computer practicals...

Course

Virtual

Registration
01 March 2024

19 March - 22 March 2024

Biological oscillators: rhythms and synchronisation across scales

19 March 20242024ConferenceEMBL Heidelberg, Virtual

Alexander Aulehla, Alan Hastings, Hanspeter Herzel, Carrie Partch

OverviewSpeakersProgrammePractical informationSponsorsAboutMedia Kit Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Symposium overview Are you interested to discuss oscillatory phenomena and biological dynamical systems accross temporal and spatial scales At this symposium multiple disciplines will come together in order to discuss... OverviewSpeakersProgrammePractical informationSponsorsAboutMedia Kit Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Symposium overview Are you interested to discuss oscillatory phenomena and biological dynamical systems, accross temporal and spatial scales? At this symposium, multiple disciplines will come together in order to discuss common themes linked to oscillations, rhythms and synchronization, in a broad range of contexts. The 2024 edition of this established symposium will expand the discussion to the scale of ecological oscillations and willl also highlight the interplay between internal and environmental rhythms. This meeting provides a unique platform to bring together a community working at the interface between quantitative biology, complex oscillatory systems, modelling and theory. As with the editions in 2015, 2018 and...

EMBO | EMBL Symposium

EMBL Heidelberg, Virtual

Registration (Virtual)
12 March 2024
Registration (On-site)
Closed
Abstract submission
Closed

19 March - 22 March 2024

Protein quality control for downstream processes

19 March 20242024CourseEMBL Heidelberg

Karine Lapouge, Kim Remans, Bertrand Raynal

OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview Course overview Purified proteins are used in various types of scientific experiments and fields For example in structural biology insights into the functional mechanisms can be obtained by elucidating the 3D molecular structure of proteins and protein complexes using technologies such as X ray crystallography cryo... OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview Course overview Purified proteins are used in various types of scientific experiments and fields. For example, in structural biology insights into the functional mechanisms can be obtained by elucidating the 3D molecular structure of proteins and protein complexes using technologies such as X-ray crystallography, cryo-EM and NMR. In biochemistry and biophysics, interactions with other proteins, nucleic acids and small molecules can be studied by determining affinities and specificities. Proteins can function as antigens to generate specific antibodies or as reagents in cell biology experiments. Furthermore, recombinant proteins can be used as tool molecules in genomics, chemical biology and microscopy assays. In order for these experiments to produce reliable and biologically relevant results, they must be performed...

Course

EMBL Heidelberg

Registration
Closed

20 March 2024

Microbial biodiversity at schools and its link with children’s health

20 March 20242024WebinarVirtual

There is a wealth of microbial diversity in the environment in soil on plants and in the atmosphere Urbanisation usually involves disturbance and sealing of soil along with a decrease and alteration of vegetation This process drastically reduces natural microbial sources such as soil and phyllosphere leaf surfaces which also contribute to enriching the atmosphere Nevertheless in an urban environment other microbial sources are more common such as wastewater treatment trash and human associated microbes Significant differences have been observed in the environmental microbial communities between urban and non urban environments Several hypotheses highlight the importance of contact with diverse natural microbial communities for human health especially for children In this webinar using a case study of the Belgian B SEBALL project we will illustrate how to investigate microbial biodiversity at school playgrounds and its potential contribution to different aspects of children s health This case study showcases the possibilities and limits of 16S rRNA amplicon sequencing in the context of the biodiversity hypothesis Does microbial diversity benefit human health The answer seems to be more nuanced than expected We will also demonstrate the power of adjusting and generating hypotheses based on field microbiome data... There is a wealth of microbial diversity in the environment, in soil, on plants, and in the atmosphere. Urbanisation usually involves disturbance and sealing of soil, along with a decrease and alteration of vegetation. This process drastically reduces natural microbial sources such as soil and phyllosphere (leaf surfaces), which also contribute to enriching the atmosphere. Nevertheless, in an urban environment, other microbial sources are more common, such as wastewater treatment, trash, and human-associated microbes. Significant differences have been observed in the environmental microbial communities between urban and non-urban environments. Several hypotheses highlight the importance of contact with diverse natural microbial communities for human health, especially for children. In this webinar, using a case study of the Belgian B@SEBALL project, we will illustrate how to...

Webinar

Virtual


27 March 2024

The Pathogens Portal: A gateway to vast biomolecular data for pathogen research

27 March 20242024WebinarVirtual

The COVID 19 pandemic starkly illuminated the crucial role of open biodata in combating infectious diseases EMBL EBI recognising this significance swiftly launched the COVID 19 Data Portal a centralised repository for SARS CoV 2 related biomolecular data Building upon this success the Pathogens Portal emerges as the spiritual successor expanding its scope to encompass a broader spectrum of pathogens The Pathogens Portal serves as a comprehensive resource for researchers clinicians and policymakers seeking access to a wealth of biomolecular data related to a diverse range of pathogens It aims to facilitate rapid knowledge discovery accelerate disease prevention and treatment strategies and foster collaboration across the scientific community This webinar introduces the Pathogens Portal to users demonstrating the why and how it exists how we decide what pathogens are included as well as a tour of the features in the portal It will deepen participants understanding of how to use the portal and introduce features that are part of the broader platform such as the datahubs a system for sharing data in a controlled access environment... The COVID-19 pandemic starkly illuminated the crucial role of open biodata in combating infectious diseases. EMBL-EBI, recognising this significance, swiftly launched the COVID-19 Data Portal, a centralised repository for SARS-CoV-2-related biomolecular data. Building upon this success, the Pathogens Portal emerges as the "spiritual" successor, expanding its scope to encompass a broader spectrum of pathogens.The Pathogens Portal serves as a comprehensive resource for researchers, clinicians, and policymakers seeking access to a wealth of biomolecular data related to a diverse range of pathogens. It aims to facilitate rapid knowledge discovery, accelerate disease prevention and treatment strategies, and foster collaboration across the scientific community.This webinar introduces the Pathogens Portal to users, demonstrating the why and how it exists, how we decide what pathogens are...

Webinar

Virtual


28 March 2024

Explore Human Pangenome Reference Consortium (HPRC) data in Ensembl

28 March 20242024WebinarVirtual

The Human Pangenome Reference Consortium HPRC aims to construct a comprehensive and representative human pangenome reference to better illustrate the genomic landscape of diverse human populations In this webinar we will guide you on how to access HPRC data via the Ensembl genome browser We will explore the available gene annotation and genetic variation data of the sequence assemblies produced by the project... The Human Pangenome Reference Consortium (HPRC) aims to construct a comprehensive and representative human pangenome reference to better illustrate the genomic landscape of diverse human populations. In this webinar, we will guide you on how to access HPRC data via the Ensembl genome browser. We will explore the available gene annotation and genetic variation data of the sequence assemblies produced by the project.

Webinar

Virtual


8 April - 12 April 2024

Data-driven approaches to understanding dementia

8 April 20242024CourseEMBL-EBI

Juanita Riveros

This course provides individuals working in dementia research with the skills to access and analyse dementia data Participants will learn to apply bioinformatics methodologies combine different data types and utilise relevant dementia data resources enhancing their research capabilities in the field... This course provides individuals working in dementia research with the skills to access and analyse dementia data. Participants will learn to apply bioinformatics methodologies, combine different data types, and utilise relevant dementia data resources, enhancing their research capabilities in the field.

Course

EMBL-EBI

Registration
Closed

8 April - 12 April 2024

scATAC-seq: attacking open chromatin in single cells

8 April 20242024CourseEMBL Heidelberg

Vladimir Benes, Ulrike Litzenburger, Judith Zaugg

ATAC Seq stands for Assay of Transposase Accessible Chromatin and is a widespread method to profile open chromatin on a genome scale The goal of this introductory course is to teach the entire workflow of a single cell and bulk ATAC Seq experiment including library preparation sequencing data processing and downstream analysis by addressing a real biological question that will be answered at the end of the course... OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview Course overview ATAC-Seq stands for Assay of Transposase Accessible Chromatin and is a widespread method to profile open chromatin on a genome-scale. The goal of this introductory course is to teach the entire workflow of a single cell ATAC-Seq experiment including library preparation, sequencing, data processing, and downstream analysis by addressing a real biological question that will be answered at the end of the course. We will start with the experimental single cell ATAC-Seq protocol, highlighting the critical steps, potential pitfalls, and the most up-to-date tweaks to improve the quality of the results. After sequencing the samples we will go through the basic quality control and preprocessing steps using multiple analysis tools for next generation sequencing data. Finally, we will perform different types of...

Course

EMBL Heidelberg

Registration
Closed

9 April - 12 April 2024

Diversity of plants: from genomes to metabolism

9 April 20242024ConferenceEMBL Heidelberg, Virtual

Barbara Ann Halkier, Sarah E. O’Connor, Detlef Weigel

OverviewSpeakersPreliminary programmePractical informationSponsorsAboutMedia kit Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Symposium overview This inaugural EMBO EMBL Symposium will showcase the future of plant biology Going beyond the limited number of wild and crop plants that have historically been focused on modern... OverviewSpeakersPreliminary programmePractical informationSponsorsAboutMedia kit Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Symposium overview This inaugural EMBO | EMBL Symposium will showcase the future of plant biology. Going beyond the limited number of wild and crop plants that have historically been focused on, modern comparative approaches are revealing the mechanistic bases and evolutionary forces driving the enormous phenotypic variation among the 400,000 plant species on Earth. This conference is for biologists with an interest in plant diversity at the genomic, (epi)genetic, phenotypic and metabolic level. The major topical threads will be the biology of genomes, evolution of metabolic pathways, and evolution of environment-dependent and -independent phenotypes, which constitute some of the most exciting areas of...

EMBO | EMBL Symposium

EMBL Heidelberg, Virtual

Registration (Virtual)
02 April 2024
Registration (On-site)
Closed
Abstract submission
Closed

15 April - 19 April 2024

Ultrastructure expansion microscopy

15 April 20242024CourseEMBL Heidelberg

Niccolo Banterle, Gautam Dey, Paul Guichard, Virginie Hamel, Marine Laporte

Expansion microscopy ExM physically magnifies specimens allowing to obtain super resolution images using a conventional diffraction limited microscope such as confocal microscopy This powerful technique is easy to implement but it requires some hands on training... OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview Course overview Expansion microscopy (ExM) physically magnifies specimens, allowing to obtain super-resolution images using a conventional diffraction-limited microscope such as confocal microscopy. This powerful technique is easy to implement but it requires some hands-on training. The gain in resolution can be further enhanced with the use of super-resolution microscopes such as STED. This course centered on the Ultrastructure Expansion Microscopy (U-ExM) based techniques applied to mammalian cells aims at disseminating and discussing expansion microscopy protocols and is intended for cell biologists, parasitologists, etc, with applications ranging from tissue to cells. Audience This course is intended for researchers ranging from PhD students to post-docs and senior scientists as well as staff from bioimaging...

EMBO Practical Course

EMBL Heidelberg

Registration
Closed

15 April - 18 April 2024

The mechanics of life: from development to disease

15 April 20242024ConferenceEMBL Heidelberg, Virtual

Prisca Liberali, Nicoletta Petridou, Amy Shyer, Andela Saric, Xavier Trepat

OverviewSpeakersPreliminary programmePractical informationSponsorsAboutMedia kit Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Symposium overview The building blocks of life macromolecules cells tissues and organs act on each other via physical forces This interplay of physical forces between the units of life gives rise to... OverviewSpeakersPreliminary programmePractical informationSponsorsAboutMedia kit Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Symposium overview The building blocks of life – macromolecules, cells, tissues, and organs – act on each other via physical forces. This interplay of physical forces between the units of life gives rise to complex behaviour — enables motility, transport, growth, division, response to environmental cues, and allows the exertion of forces on the environment, bridging biological scales. The alteration of forces and mechanical properties is associated with inflammation, cancer, and ageing. This comprehensive symposium will study the interplay of the physical forces — the mechanics — between the fundamental building blocks of life, from molecules to organs. It will cover how these physical forces enable development...

EMBO | EMBL Symposium

EMBL Heidelberg, Virtual

Registration (Virtual)
08 April 2024
Registration (On-site)
04 March 2024
Abstract submission
Closed

17 April 2024

Statistical thinking for microbial ecology

17 April 20242024WebinarVirtual

Most microbial ecologists understand the importance of rigorous statistical analysis for conducting a replicable study However formal courses in the statistical analysis of high dimensional ecological data are rare and traditional courses in applied statistics may not teach skills applicable to modern microbiome analysis This webinar will introduce foundational concepts in statistics with a focus on applying these concepts to the analysis of modern microbiome datasets To illustrate these concepts we will use the field of differential abundance as a case study We will contrast popular differential abundance parameters and estimators specifically focusing on estimating meaningful contrasts using high throughput sequencing data... Most microbial ecologists understand the importance of rigorous statistical analysis for conducting a replicable study. However, formal courses in the statistical analysis of high-dimensional ecological data are rare, and traditional courses in applied statistics may not teach skills applicable to modern microbiome analysis.This webinar will introduce foundational concepts in statistics, with a focus on applying these concepts to the analysis of modern microbiome datasets. To illustrate these concepts, we will use the field of "differential abundance" as a case study. We will contrast popular differential abundance parameters and estimators, specifically focusing on estimating meaningful contrasts using high-throughput sequencing data.

Webinar

Virtual


22 April - 26 April 2024

Fundamentals of widefield and confocal microscopy and imaging

22 April 20242024CourseEMBL Heidelberg

Heiko Gaethje, Jens Marquard

This course will provide the participants with an overview of the basics of microscopy light and optics contrast techniques and imaging... OverviewSpeakersPreliminary programmePractical informationSponsorsMedia kit Overview Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Course overview Light microscopy is the most widely used form of microscopy for life science research. The correct handling of the microscope and optimising image quality (e.g. contrast, resolution) as well as experimental design according to different applications are crucial to obtain the best results. This course will provide the participants with an overview of the basics of microscopy (light and optics, contrast techniques and imaging). The confocal part will include multicolour, 3D, and time-lapse imaging as well as spectral imaging, introduction to photobleaching and photoactivation techniques. Basic image analysis tools including measurement functions, colocalisation,...

Course

EMBL Heidelberg

Registration
Closed

22 April - 26 April 2024

Microscopy data analysis: machine learning and the BioImage Archive

22 April 20242024CourseVirtual

Meredith Willmott

This virtual course will show how public bioimaging data resources centred around the BioImage Archive enable and enhance machine learning based image analysis The content will explore a variety of data types including electron and light microscopy and miscellaneous or multi modal imaging data at the cell and tissue scale Participants will cover contemporary biological image analysis with an emphasis on machine learning methods as well as how to access and use images from databases Further instruction will be offered using applications such as ZeroCostDL4Mic ilastik the BioImage Model Zoo and CellProfiler Virtual course This course will be a virtual event delivered via a mixture of live streamed sessions pre recorded lectures and tutorials with live support We will be using Zoom to run the live sessions all fully password protected with automated English closed captioning and transcription with support and both scientific and social networking opportunities provided by Slack and other methods taking different time zones into account In order to make the most out of the course you should make sure to have a stable internet connection throughout the week and are available between 08 00 18 00 BST each day In the week before the course there will be a brief induction session Computational practicals will run on EMBL EBI s virtual training infrastructure meaning participants will not require access to a powerful computer or install complex software on their own machines Selected participants may be sent materials prior to the course These might include pre recorded talks and required reading or online training that will be essential to fully engage with the course... This virtual course will show how public bioimaging data resources, centred around the BioImage Archive, enable and enhance machine learning based image analysis. The content will explore a variety of data types including electron and light microscopy and miscellaneous or multi-modal imaging data at the cell and tissue scale. Participants will cover contemporary biological image analysis with an emphasis on machine learning methods, as well as how to access and use images from databases. Further instruction will be offered using applications such as ZeroCostDL4Mic, ilastik, the BioImage Model Zoo, and CellProfiler. Virtual course This course will be a virtual event delivered via a mixture of live-streamed sessions, pre-recorded lectures, and tutorials with live support. We will be using Zoom to run the live sessions (all fully password protected with automated English closed captioning...

Course

Virtual

Registration
Closed

23 April - 26 April 2024

Organismal physiology

23 April 20242024ConferenceEMBL Heidelberg, Virtual

Gerard Karsenty, Irene Miguel-Aliaga, Asya Rolls, Miguel Soares

This symposium aims to provide a high visibility platform to scientists from multiple disciplines who use molecular genetic tools to probe inter organ communication signals that maintain homeostasis It will also directly address a fundamental and long term goal of the study of physiology how can recent developments in whole organism physiology pave the way to novel adapted and efficient therapies for multiple degenerative diseases... OverviewSpeakersPreliminary programmePractical informationSponsorsAbout Overview We regret to inform you that this event has been cancelled. Please have a look at our other upcoming events here. Symposium overview “Like a machine, any organism, even the simplest, is a functional unit, coherent and integrated. We are far from having elucidated, in complex organisms, the entire structure of these functional units”. A major outcome of research using model organisms has been to address this central question of biology that was stated so clearly and candidly by J. Monod in 1969. Genetic studies in model organism have first revealed that we are far from knowing all the functions fulfilled by various organs in vertebrates or invertebrates. In doing so, this body of work has nonetheless led to unprecedented progress in our understanding of how homeostasis of an entire organism is maintained. As...

EMBO | EMBL Symposium

EMBL Heidelberg, Virtual

Registration
Will open shortly

1 May 2024

Harmony in diversity: exploring the rich microbiomes of South American wildlife

1 May 20242024WebinarVirtual

Colombia and northern South America is known as a biodiversity hotspot but at the basis of that diversity is the microbial communities With recent advances in metagenomics the microbial communities and genomic composition has started to be characterised by unveiling a whole new world that is highly interconnected with macro organisms and the environment This webinar will illustrate the intricate world of microbial communities associated with diverse South American fauna From the high altitude realms of neotropical bumblebees to the depths of coral reefs we ll journey through the microbiome landscapes of beings like spectacled bears woolly monkeys lichens shrimps among others Discover the unseen connections shaping the health and resilience of these unique ecosystems... Colombia and northern South America is known as a biodiversity hotspot, but at the basis of that diversity is the microbial communities. With recent advances in metagenomics, the microbial communities and genomic composition has started to be characterised by unveiling a whole new world that is highly interconnected with macro-organisms and the environment.This webinar will illustrate the intricate world of microbial communities associated with diverse South American fauna. From the high-altitude realms of neotropical bumblebees to the depths of coral reefs, we'll journey through the microbiome landscapes of beings like spectacled bears, woolly monkeys, lichens, shrimps, among others. Discover the unseen connections shaping the health and resilience of these unique ecosystems.

Webinar

Virtual


6 May - 8 May 2024

Building networks 2024: engineering in vascular biology

6 May 20242024ConferenceEMBL Barcelona

Maria Bernabeu, Claudio Franco, Stephan Huveneers, Milica Radisic

In this meeting we intend to bring together vascular biologists and bioengineers from across the world to build research synergies to tackle long standing questions in the field of vascular biology... OverviewSpeakersPreliminary programmePractical informationSponsorsMedia kit Overview This conference will take place at EMBL Barcelona. Conference overview Blood vessels are essential for the formation and maintenance of larger tissues and organs. The vascular system regulates exchange of oxygen, nutrients and immune cells – the dysfunction of which can cause severe pathologies. Mouse models, genetics and histology of human samples, coupled with recent advances in imaging, single-cell approaches and computational modelling, have provided significant knowledge to the field of vascular biology. Yet, in vivo models are highly complex and often need to be combined with simpler in vitro studies to get mechanistic and molecular insights. Growth of in vitro blood vessels presents numerous research challenges due to their complex 3D geometry, and a strong coupling between biology and...

EMBO Workshop

EMBL Barcelona

Registration (Virtual)
29 April 2024
Registration (On-site)
25 March 2024
Abstract submission
Closed

8 May 2024

Wine yeasts as a model system in community ecology

8 May 20242024WebinarVirtual

Wine fermentation constitutes a transient microbial ecosystem wherein numerous yeast species originating from the grape surface engage in interactions This leads to an ecological succession anticipated to culminate in the ultimate dominance of Saccharomyces cerevisiae The diversity of yeast species found in grape musts has a direct impact on the final chemical and aroma complexity of the resulting wines Understanding the molecular and ecological interaction patterns between wine yeast communities is essential to harness diverse yeast functionalities with the final aim of producing tailored high quality wines In this seminar we will introduce the expectable phylogenetic and functional diversity in wine yeast communities we will discuss how to engineer wine yeast communities top down and bottom up and we will finally conclude about the necessity of adopting the adequate theoretical framework to address challenging questions in applied ecology and to finally improve microbiome based industrial processes... Wine fermentation constitutes a transient microbial ecosystem wherein numerous yeast species, originating from the grape surface, engage in interactions. This leads to an ecological succession anticipated to culminate in the ultimate dominance of Saccharomyces cerevisiae. The diversity of yeast species found in grape musts has a direct impact on the final chemical and aroma complexity of the resulting wines. Understanding the molecular and ecological interaction patterns between wine yeast communities is essential to harness diverse yeast functionalities, with the final aim of producing tailored high-quality wines. In this seminar we will introduce the expectable phylogenetic and functional diversity in wine yeast communities, we will discuss how to engineer wine yeast communities (top-down and bottom-up), and we will finally conclude about the necessity of adopting the adequate...

Webinar

Virtual


12 May - 17 May 2024

Advanced fluorescence imaging techniques

12 May 20242024CourseEMBL Heidelberg

Manuel Gunkel, Aliaksandr Halavatyi, Debora Keller-Olivier Joana Delgado Martins, Irina Rakotoson

This practical course will cover advanced light microscopy techniques and participants will learn how to derive qualitative and quantitative insights on molecular mechanisms in cells and developing organisms Invited guest researchers together with experts from the EMBL and microscopy professionals will foster an intense information flow with a balance of lectures and practical workshops The focus of the course will be on the use of fluorescence microscopy to obtain information about protein localisation dynamics and functions at different spatial scales... OverviewSpeakersPreliminary programmePractical informationSponsorsMedia Kit Overview Course overview This practical course will cover advanced light microscopy techniques and participants will learn how to derive qualitative and quantitative insights on molecular mechanisms in cells and developing organisms. Invited guest researchers together with microscopy experts from EMBL will foster an intense information flow with a balance of lectures and practical workshops. The focus of the course will be on the use of fluorescence microscopy to obtain information about localisation and functions of proteins and other bio-molecules at different spatial scales. Audience This course is directed towards researchers in the life sciences with access to light microscopy equipment, who have an immediate need to apply the techniques they will learn to solve biological problems at the cellular and...

EMBL Course

EMBL Heidelberg

Registration
Closed

14 May - 17 May 2024

Introduction to metabolomics analysis

14 May 20242024CourseEMBL-EBI

Meredith Willmott

This course will provide an introduction to metabolomics through lectures and hands on sessions using publicly available data software and tools Participants will become familiar with standardised workflows as well as with the current state of experimental design data acquisition LC MS MS imaging processing and modelling In addition they will learn about community standards and sharing in metabolomics particularly through the use of EMBL EBI s MetaboLights repository and Galaxy infrastructure Participants will learn through hands on tutorials to use tools available for data analysis and data submission Additionally case studies will be discussed to show how to employ the week s learning... This course will provide an introduction to metabolomics through lectures and hands-on sessions, using publicly available data, software, and tools. Participants will become familiar with standardised workflows as well as with the current state of experimental design, data acquisition (LC-MS, MS imaging), processing, and modelling. In addition, they will learn about community standards and sharing in metabolomics, particularly through the use of EMBL-EBI’s MetaboLights repository and Galaxy infrastructure. Participants will learn through hands-on tutorials to use tools available for data analysis and data submission. Additionally, case studies will be discussed to show how to employ the week’s learning.

Course

EMBL-EBI

Registration
Closed

14 May - 17 May 2024

Cellular mechanisms driven by phase separation

14 May 20242024ConferenceEMBL Heidelberg, Virtual

Simon Alberti, Sara Cuylen-Häring, Dorothee Dormann, Alex Holehouse

This conference will bring together scientists from soft matter polymer physics molecular biology structural biology and cell and developmental biology to study condensates in biology and disease... OverviewSpeakersPreliminary programmePractical informationSponsorsAboutMedia kit Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Symposium overview Phase separation is emerging as a common biophysical principle underlying many important cellular functions. This conference will bring together scientists from cell biology, biophysics, biochemistry, molecular biology, structural biology, developmental biology, polymer physics, and soft matter physics to study condensates in biology and disease. The goals of this symposium are to: increase our understanding of the physiological relevance of condensates in many biological processes explore the large repertoire of new tools and methods that can be applied to study the phenomenon of biological condensates provide transdisciplinary training to tackle the role of condensates in biology Session...

EMBO | EMBL Symposium

EMBL Heidelberg, Virtual

Registration (Virtual)
07 May 2024
Registration (On-site)
02 April 2024
Abstract submission
Closed

21 May - 23 May 2024

BioMalPar XX: biology and pathology of the malaria parasite

21 May 20242024ConferenceEMBL Heidelberg, Virtual

Sabrina Absalon, Jess Bryant, Fredros Okumu, Taco Kooij

OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview This conference will take place at EMBL Heidelberg with the option to attend virtually The deadline to apply for financial assistance for on site participation with abstract is 13 February 2024 Conference overview Malaria remains a major global public health challenge The emergence and spread of resistance to... OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. The deadline to apply for financial assistance for on-site participation with abstract is 13 February 2024. Conference overview Malaria remains a major global public health challenge. The emergence and spread of resistance to existing antimalarial drugs further complicates the fight against this ancient foe. As the BioMalPar Conference marks its 20th anniversary, we would like to take a moment to reflect on the critical mission of understanding the biology of the Plasmodium parasite, its interactions with hosts and vectors, and the urgent need to develop effective intervention strategies. This year, we will focus on enhancing our research community by forging new connections. We recognize that meaningful progress in combating...

EMBL Conference

EMBL Heidelberg, Virtual

Registration (Virtual)
14 May 2024
Registration (On-site)
09 April 2024
Abstract submission
05 March 2024

26 May - 31 May 2024

Whole transcriptome data analysis

26 May 20242024CourseEMBL Heidelberg

Marco Beccuti, Vladimir Benes, Raffaele Calogero, Francesca Cordero

This course will teach the biological researchers how to analyse biological data sets using open source software Most of the analysis will be performed with docker4seq and rCASC packages which was developed to facilitate the use of computing demanding applications in the field of NGS data analysis... OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview Course overview This course will teach the biological researchers how to analyse biological data sets using open-source software. Most of the analysis will be performed with docker4seq and rCASC packages, which was developed to facilitate the use of computing demanding applications in the field of NGS data analysis. Docker4seq and rCASC packages use docker containers that embed demanding computing tasks (e.g. short reads mapping) into isolated containers. This approach provides multiple advantages: the user does not need to install all the software on its local server, the results generated by different containers can be organised in pipelines and reproducible research is guarantee by the possibility of sharing the docker images used for the analysis. Computers for hands-on exercises will be provided along with demo...

Course

EMBL Heidelberg

Registration
03 March 2024

1 June - 8 June 2024

Structural characterisation of macromolecular complexes

1 June 20242024CourseEMBL Grenoble

Ana Casanal, Wojciech Galej, Eva Kowalinski, Carlo Petosa, Montserrat Soler López

OverviewSpeakers and trainersPreliminary programmePractical informationSponsorsMedia kit Overview Course overview Recent developments in cryo EM ET super resolution microscopy and protein structure prediction coupled with increasingly sophisticated methods of sample preparation have revolutionised structural biology Educating the next generation of researchers on how to... OverviewSpeakers and trainersPreliminary programmePractical informationSponsorsMedia kit Overview Course overview Recent developments in cryo-EM/ET, super-resolution microscopy, and protein structure prediction — coupled with increasingly sophisticated methods of sample preparation — have revolutionised structural biology. Educating the next generation of researchers on how to strategically combine these disparate tools is critical for addressing the most challenging structural biology problems of the future. Course participants will receive a comprehensive overview of state-of-the-art structural methods, with a focus on sample preparation, characterisation, and data integration strategies. Key aspects covered by lectures and practicals include multi-subunit protein expression in bacteria, insect, and mammalian cells; isolation of native complexes and in-vitro reconstitution of protein...

EMBO Practical Course

EMBL Grenoble

Registration
10 March 2024

5 June - 8 June 2024

Microtubules: from atoms to complex systems

5 June 20242024ConferenceEMBL Heidelberg, Virtual

Carsten Janke, Thomas Müller-Reichert, Shinsuke Niwa, Kassandra Ori-Mckenney

In recent years interdisciplinary approaches embracing cell biology genetics molecular biology biochemistry biophysics structural biology and mathematical modelling have made a tremendous impact on the microtubule field... OverviewSpeakersPreliminary ProgrammeAboutPractical infomationSponsorsMedia kit Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Symposium overview This symposium, initiated in 2010, has taken place every second year since and brings together early-career and established researchers from all over the world who are interested in microtubule biology and its impact on human health and disease. The microtubule cytoskeleton is essential for a wide variety of cellular functions, such as chromosome segregation, directed vesicle and organelle transport, cell motility, and cell polarity. Impaired microtubule function can lead to human diseases including cancer and neurodegenerative disorders, where microtubules serve as important therapeutic targets. In recent years, interdisciplinary approaches embracing cell biology, genetics, molecular biology,...

EMBO | EMBL Symposium

EMBL Heidelberg, Virtual

Registration (Virtual)
29 May 2024
Registration (On-site)
24 April 2024
Abstract submission
13 March 2024

9 June - 15 June 2024

C. elegans: from genome editing to imaging

9 June 20242024CourseEMBL Heidelberg

Henrik Bringmann, Simone Koehler, Georgia Rapti, Pavak Shah

OverviewSpeakersPreliminary ProgrammePractical informationSponsorsMedia kit Overview Course overview C elegans is a popular experimental model that combines transparency reproducible anatomy traceable cell lineage sequenced genome and facile genetics allowing to dissect animal development physiology and behaviour across scales of genes cells and tissues This 7 day course will... OverviewSpeakersPreliminary ProgrammePractical informationSponsorsMedia kit Overview Course overview C. elegans is a popular experimental model that combines transparency, reproducible anatomy, traceable cell lineage, sequenced genome and facile genetics, allowing to dissect animal development, physiology, and behaviour across scales of genes, cells and tissues. This 7-day course will present experimental practices in C. elegans research, while introducing historic and up-to-date findings in various research topics. Each day includes lectures, practicals, student poster presentations and interactive discussions with faculty. Various methodologies commonly employed in C. elegans research will be presented in parallel practicals with rotating student groups by relevant experts. These experimental techniques span forward and reverse genetics, genome editing, lineaging, imaging approaches...

EMBO Practical Course

EMBL Heidelberg

Registration
17 March 2024

10 June - 14 June 2024

Systems biology: from large datasets to biological insight

10 June 20242024CourseEMBL-EBI

Juanita Riveros

This course covers the use of computational tools to extract biological insight from omics datasets The content will explore a range of approaches ranging from network inference and data integration to machine learning and logic modelling that can be used to extract biological insights from varied data types Together these techniques will provide participants with a useful toolkit for designing new strategies to extract relevant information and understanding from large scale biological data The motivation for running this course is a result of advances in computer science and high performance computing that have led to groundbreaking developments in systems biology model inference With the comparable increase of publicly available large scale biological data the challenge now lies in interpreting them in a biologically valuable manner Likewise machine learning approaches are making a significant impact in our analysis of large omics datasets and the extraction of useful biological knowledge... This course covers the use of computational tools to extract biological insight from omics datasets. The content will explore a range of approaches – ranging from network inference and data integration to machine learning and logic modelling – that can be used to extract biological insights from varied data types. Together these techniques will provide participants with a useful toolkit for designing new strategies to extract relevant information and understanding from large-scale biological data.The motivation for running this course is a result of advances in computer science and high-performance computing that have led to groundbreaking developments in systems biology model inference. With the comparable increase of publicly-available, large-scale biological data, the challenge now lies in interpreting them in a biologically valuable manner. Likewise, machine learning approaches are...

Course

EMBL-EBI

Registration
03 March 2024

17 June - 21 June 2024

Summer school in bioinformatics

17 June 20242024CourseEMBL-EBI

Sophie Spencer

This course provides an introduction to the use of bioinformatics in biological research giving you guidance for using bioinformatics in your work whilst also providing hands on training in tools and resources appropriate to your research You will initially be introduced to bioinformatics theory and practice including best practices for undertaking bioinformatics analysis data management and reproducibility You will be required to review some pre recorded material for their group project prior to the start of the course Group projectsA major element of this course is a group project where you ll be placed in small groups to work together on a challenge set by trainers from EMBL EBI and external institutes This allows you to explore the bioinformatics tools and resources available in your area of interest and apply them to a set problem providing you with hands on experience relevant to your own research The group work will culminate in a presentation session involving everyone on the final day of the course giving an opportunity for wider discussion on the benefits and challenges of working with biological data Groups are mentored and supported by the trainers who set the initial challenge but the groups will be responsible for driving their projects forward with all members expected to take an active role Groups are pre organised before the course and all group members will be sent some short homework in preparation for your project work prior to the start of the course Basic outlines of the projects on offer this year are given below In your application you must indicate your first and second choice of project based on which you think would benefit your research most Not all projects may be offered and final decisions on which projects will be run during the course will be made based on the number of applicants per project Most of the projects cover mammalian data sets however in many cases the methods and approaches taught are transferable to data from various species Group project one Genome variation across human populations Natural variation between individuals or between different human populations is a result of genome mutations throughout evolutionary history Some mutations may become fixed because of their beneficial effect while most drift among individuals During this project you will investigate genomic variation between two separate human populations of European and Asian descent Using sequence data from a number of individuals from each population you will use a range of bioinformatics tools to discover variants that exist between them In the second section of the project you will attempt to analyse the functional consequences of the variants you have identified attempting to find clinical association and linking them to phenotypes Project mentor Anu Shivalikanjli EMBL EBI Group project two Interpreting functional information from large scale protein structure dataThis project will introduce you to the wealth of publicly available data in the Protein Data Bank PDB and give you the opportunity to investigate how large subsets of structure data can be used to analyse protein features and determine function In the project you will learn how to identify relevant protein structures collate and interpret functional information and implement this process programmatically Project mentor Marcus Bage EMBL EBI and Joseph Ellaway EMBL EBIGroup project three Modelling cell signalling pathwaysCurating models of biological processes is an effective training in computational systems biology where the curators gain an integrative knowledge of biological systems modelling and bioinformatics You will learn to encode and simulate ordinary differential equation models of signalling pathways from a recent publication using user friendly software such as COPASI even without extensive mathematical background You will learn to perform in silico experiments new predictions and develop hypotheses Furthermore you will learn how to annotate models and re use pre existing models from open repositories such as BioModels Project mentors Rahuman Sheriff EMBL EBI and Krishna Tiwari EMBL EBI Group project four Improving AI based bioimage analysis Artificial Intelligence AI algorithms outperform classical image analysis methods however the performance of these models is highly dependent on the quality of the annotated image datasets used to train them In this project you will explore the application of AI for biological imaging and the relationship between model training data and model performance You will use models stored in the BioImage Model Zoo and data in the BioImage Archive to fine tune and aggregate AI outputs The aim of this project will be to test evaluate and improve model performance on a diverse set of microscopy images and annotations within the BioImage Archive You will learn how to apply train tune and employ the most performant state of the art computer vision models This project serves as a valuable demonstration of how FAIR Findable Accessible Interoperable Reusable data plays an essential role in the training and enhancement of AI models Project mentors Aybuke Kupcu Yoldas EMBL EBI and Craig Russel EMBL EBI Group project five Single cell RNA sequencing analysis with PythonIn this project you will learn how to perform single cell RNA sequencing data analysis to investigate cell type heterogeneity and expression differences across conditions The analysis will be based on the SCANPY framework in Python You will start by collecting the raw count matrix and relevant metadata from the Single cell Expression Atlas After constructing the AnnData objects you will perform quality control preprocessing dimensionality reduction cell type annotation and differential expression analysis We will also explore the batch effect and its correction Project mentors Yuyao Song EMBL EBI and Anna Vathrakokoili Pournara EMBL EBI Group project six Networks and pathwaysThis project will cover typical bioinformatics analysis steps needed to put differentially expressed genes into a wider biological context You will start with gene expression data RNA seq to build an initial interaction network Next you will learn to combine public network datasets identify key regulators of biological pathways and explore biological function through network analysis You will get first hand experience in integration and co visualising with additional data and functional enrichment analysis All this helps to put the initial results into a previously known context and provide hypotheses for potential follow up experiments We will use Cytoscape Expression Atlas g Profiler StringDb among other tools We may also give a few R packages a try Project mentor Priit Adler University of Tartu... This course provides an introduction to the use of bioinformatics in biological research, giving you guidance for using bioinformatics in your work whilst also providing hands-on training in tools and resources appropriate to your research.You will initially be introduced to bioinformatics theory and practice, including best practices for undertaking bioinformatics analysis, data management, and reproducibility. You will be required to review some pre-recorded material for their group project prior to the start of the course.Group projectsA major element of this course is a group project, where you'll be placed in small groups to work together on a challenge set by trainers from EMBL-EBI and external institutes. This allows you to explore the bioinformatics tools and resources available in your area of interest and apply them to a set problem, providing you with hands-on experience...

Course

EMBL-EBI

Registration
Closed

18 June - 21 June 2024

Innate immunity in host-pathogen interactions

18 June 20242024ConferenceEMBL Heidelberg, Virtual

Gordon Brown, Michaela Gack, Felix Randow, Dominique Soldati-Favre, Cyril Zipfel

OverviewSpeakersPreliminary programmePractical informationSponsorsAboutMedia kit Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Symposium overview This follow up meeting to the successful EMBO EMBL Symposia Innate immunity in Host Pathogen Interactions in 2016 2018 and 2022 will provide a discussion and networking platform for all... OverviewSpeakersPreliminary programmePractical informationSponsorsAboutMedia kit Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Symposium overview This follow-up meeting to the successful EMBO | EMBL Symposia ‘Innate immunity in Host Pathogen Interactions’ in 2016, 2018 and 2022 will provide a discussion and networking platform for all scientists interested in the biology of pathogen infection. The symposium will promote the exchange of conceptual ideas in this rapidly evolving field, and also foster cross-disciplinary collaborations among the scientists. Innate immunity is studied by both microbiologists and immunologists; however, their perspectives differ widely. Microbiologists are necessarily specialists for their pathogen(s) of choice, while immunologists tend to focus on the host response. The goal of the conference is...

EMBO | EMBL Symposium

EMBL Heidelberg, Virtual

Registration (Virtual)
11 June 2024
Registration (On-site)
07 May 2024
Abstract submission
26 March 2024

24 June - 28 June 2024

Cancer genomics and transcriptomics

24 June 20242024CourseVirtual

Meredith Willmott

This course will focus on the analysis of data from genomic studies of cancer It will also highlight the application of transcriptomic analysis and single cell technologies in cancer Talks and interactive sessions will give an insight into the bioinformatic concepts required to analyse such data whilst practical sessions will enable the participants to apply statistical methods to the analysis of cancer genomics data under the guidance of the trainers Virtual courseParticipants will learn via a mix of pre recorded lectures live presentations and trainer Q A sessions Practical experience will be developed through group activities and trainer led computational exercises Live sessions will be delivered using Zoom with additional support and asynchronous communication via Slack Pre recorded material may be provided before the course starts that participants will need to watch read or work through to gain the most out of the actual training event In the week before the course there will be a brief induction session Computational practicals will run on EMBL EBI s virtual training infrastructure meaning participants will not require access to a powerful computer or install complex software on their own machines Participants will need to be available between the hours of 08 45 17 00 BST each day of the course Trainers will be available to assist answer questions and provide further explanations during these times... This course will focus on the analysis of data from genomic studies of cancer. It will also highlight the application of transcriptomic analysis and single-cell technologies in cancer. Talks and interactive sessions will give an insight into the bioinformatic concepts required to analyse such data, whilst practical sessions will enable the participants to apply statistical methods to the analysis of cancer genomics data under the guidance of the trainers.Virtual courseParticipants will learn via a mix of pre-recorded lectures, live presentations, and trainer Q&A sessions. Practical experience will be developed through group activities and trainer-led computational exercises. Live sessions will be delivered using Zoom with additional support and asynchronous communication via Slack.Pre-recorded material may be provided before the course starts that participants will need to watch,...

Course

Virtual

Registration
31 March 2024

1 July - 5 July 2024

Bioinformatics for immunologists

1 July 20242024CourseEMBL-EBI

Juanita Riveros

This course will provide participants with an introduction to a range of bioinformatics resources and approaches applicable to immunological research Participants will gain experience in analysis pipelines for NGS experiments relevant to immunology including immune receptor sequencing RNA sequencing single cell RNA sequencing and flow cytometry data analysis Additionally participants will be introduced to how data from several sources can be integrated to provide a wider view of their research thereby enabling them to be more confident users of their own data and that from public sources... This course will provide participants with an introduction to a range of bioinformatics resources and approaches applicable to immunological research. Participants will gain experience in analysis pipelines for NGS experiments relevant to immunology including immune receptor sequencing, RNA sequencing, single-cell RNA sequencing, and flow cytometry data analysis.Additionally, participants will be introduced to how data from several sources can be integrated to provide a wider view of their research, thereby enabling them to be more confident users of their own data and that from public sources.

Course

EMBL-EBI

Registration
17 March 2024

8 July - 12 July 2024

Time-resolved macromolecular serial crystallography

8 July 20242024CourseEMBL Grenoble

Oskar Aurelius, Shibom Basu, Gisela Brändé, Arwen Pearson, Daniele de Sanctis

OverviewSpeakers and trainersPreliminary programmePractical informationSponsorsMedia kit Overview Course overview The advent of serial crystallography at free electron laser sources and the following adaptation of these methods at 3rd and 4th generation synchrotrons have opened new possibilities to perform room temperature time resolved studies in macromolecular crystallography This... OverviewSpeakers and trainersPreliminary programmePractical informationSponsorsMedia kit Overview Course overview The advent of serial crystallography at free electron laser sources and the following adaptation of these methods at 3rd and 4th generation synchrotrons have opened new possibilities to perform room temperature time resolved studies in macromolecular crystallography. This course aims to train the next generation of researchers ini) sample preparation: Participants will be trained and taught in the best practice to obtain homogenous microcrystals and in characterisation prior to loading using different sample delivery methods,ii) crystal delivery methods and data collection at a 4th generation synchrotron serial crystallography beamline: The new ID29 and similar endstations at other sources, presents experimental setup and data collection protocols that are unique in the...

EMBO Practical Course

EMBL Grenoble

Registration
15 April 2024

8 July - 13 July 2024

Time-resolved STED nanoscopy in life sciences

8 July 20242024CourseEMBL Heidelberg

Marko Lampe, Andrea Mülter, Manuel Gunkel, Julia Roberti

OverviewSpeakersPreliminary ProgrammePractical informationSponsorsMedia kit Overview Course overview This six day comprehensive advanced microscopy course focuses on stimulated emission depletion microscopy STED and its application to biological questions Through lectures tutorials and practical workshops the course provides in depth knowledge on all aspects of STED Nanoscopy It... OverviewSpeakersPreliminary ProgrammePractical informationSponsorsMedia kit Overview Course overview This six-day comprehensive advanced microscopy course focuses on stimulated emission depletion microscopy (STED) and its application to biological questions. Through lectures, tutorials and practical workshops, the course provides in-depth knowledge on all aspects of STED Nanoscopy. It covers the fundamentals of STED microscopy, different technical implementations and has a strong emphasis on sample preparation – including choice of fluorophores and refractive index matching, as well as image acquisition strategies for fixed samples and living cells. Students will have the opportunity for exercises on state-of the art STED microscopes in which they will acquire high quality nanoscopy data. The faculty consists of invited guest researchers, experts from the EMBL and Leica Microsystems....

EMBL Course

EMBL Heidelberg

Registration
15 April 2024

15 July - 19 July 2024

Proteomics bioinformatics

15 July 20242024CourseEMBL-EBI

Sophie Spencer

This course provides hands on training in the basics of mass spectrometry MS and proteomics bioinformatics You will receive training on how to use search engines and post processing software quantitative approaches MS data repositories the use of public databases for protein analysis annotation of subsequent protein lists and incorporation of information from molecular interaction and pathway databases The practical elements of the course will take raw data from a proteomics experiment and analyse it You will be able to go from MS spectra to identifying and quantifying peptides and finally to obtaining lists of protein identifiers that can be analysed further using a wide range of resources The final aim is to provide you with the practical bioinformatics knowledge you need to go back to the lab and process your own data when collected This course is organised in association with the Vlaams Instituut voor Biotechnologie VIB the Flemish Institute for Biotechnology Pre recorded material may be provided before the course starts that you will need to watch read or work through to gain the most out of the actual training event In person courseThe course fee is inclusive of four nights of accommodation and catering including dinner We plan to deliver this course in person onsite at our training suite at EMBL EBI Hinxton Please be aware that we are continually evaluating the ongoing pandemic situation and as such may need to change the format of courses at short notice Your safety is paramount to us you can read our COVID guidance policy for more information All information is correct at time of publishing... This course provides hands-on training in the basics of mass spectrometry (MS) and proteomics bioinformatics. You will receive training on how to use search engines and post-processing software, quantitative approaches, MS data repositories, the use of public databases for protein analysis, annotation of subsequent protein lists, and incorporation of information from molecular interaction and pathway databases.The practical elements of the course will take raw data from a proteomics experiment and analyse it. You will be able to go from MS spectra to identifying and quantifying peptides, and finally to obtaining lists of protein identifiers that can be analysed further using a wide range of resources. The final aim is to provide you with the practical bioinformatics knowledge you need to go back to the lab and process your own data when collected.This course is organised in association...

Course

EMBL-EBI

Registration
07 April 2024

18 August - 26 August 2024

Advances in cryo-electron microscopy and 3D image processing

18 August 20242024CourseEMBL Heidelberg

Julia Mahamid, Sebastian Eustermann, Simone Mattei, Lori Passmore, Henning Stahlberg

This course provides the theoretical and practical foundations of advanced cryoEM techniques from sample preparation to data collection to image processing... OverviewSpeakersSponsorsPractical informationMedia kit Overview Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Course overview Cryo-electron microscopy (cryoEM) has become the method of choice for determining atomic-level structures of large and flexible macromolecular assemblies that are notoriously difficult to study by other techniques. In addition, it has unique capabilities for obtaining structural information in situ, within complex (cellular) environments, and to deal with biologically heterogeneous samples. With the advent of the cryoEM “resolution revolution”, the method has undergone a tremendous growth in user base. Yet, the underlying methods are complex and under constant development. Therefore, in depth advanced training is essential to ensure future generations can adapt emerging technologies...

EMBO Practical Course

EMBL Heidelberg

Registration
Will open shortly

24 August - 27 August 2024

Transcription and chromatin

24 August 20242024ConferenceEMBL Heidelberg, Virtual

Shelley Berger, Eileen Furlong, Luca Giorgetti, Jürg Müller

The meeting brings together leading experts covering all aspects of transcription including cis regulatory function long range regulation 3 dimensional looping the basal transcriptional machinery RNA polymerase regulation and function nucleosome positioning chromatin modifications chromatin remodelling and epigenetic inheritance of transcriptional silencing... OverviewSpeakersPreliminary programmePractical informationSponsorsMedia kit Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Conference overview The EMBL ‘Transcription and chromatin’ conference has a long-standing tradition in shaping the field of transcriptional regulation. The meeting brings together leading experts covering all aspects of transcription including cis-regulatory function, long range regulation, 3-dimensional looping, the basal transcriptional machinery, RNA polymerase regulation and function, nucleosome positioning, chromatin modifications, chromatin remodelling, and epigenetic inheritance of transcriptional silencing. The meeting contains many talks selected from the abstracts that are interspersed with invited speakers, discussing the latest breakthroughs in transcriptional regulation. The conference is...

Conference

EMBL Heidelberg, Virtual

Registration (Virtual)
19 August 2024
Registration (On-site)
15 July 2024
Abstract submission
03 June 2024

1 September - 10 September 2024

Current methods in cell biology

1 September 20242024CourseEMBL Heidelberg

Niccolò Banterle, Beth Cimini, Simone Koehler

The course aims to expose researchers with different backgrounds to the diverse cutting edge methods developed for cell biology to showcase how integrated approaches can address the current big questions in cell biology... OverviewSpeakersPreliminary programmePractical informationSponsorsMedia kit Overview Course overview In the past decade, cell biology has undergone transformational changes resulting from improvements in single molecule imaging technologies and in-situ structural biology. At the same time, the emergence of deep learning approaches that have revolutionised the field of image analysis together with techniques that complement imaging approaches to e.g. dissect the mechanical properties of cells have provided a wealth of quantitative high-dimensional data for cell biologists. The wealth of data available to cell biologists also comes with new challenges in data handling, data analysis, and data interpretation. To allow researchers to design appropriate experiments and translate the data into meaningful knowledge requires insight into which techniques are best suited to address a specific...

Course

EMBL Heidelberg

Registration
09 June 2024

1 September - 6 September 2024

Genome engineering: CRISPR/Cas in cells and mice

1 September 20242024CourseEMBL Heidelberg

Neil Humphreys, Kristof Kersse, Birgit Koch, Elisabeth Zielonka

OverviewSpeakersPreliminary programmePractical informationSponsorsMedia kit Overview Course overview This course will provide training in genome editing and cell engineering in mammalian cells and mouse embryos using the highly efficient CRISPR Cas9 system Participants will learn design of CRISPR targets using bioinformatics tools generation of gene knock outs knock ins and target... OverviewSpeakersPreliminary programmePractical informationSponsorsMedia kit Overview Course overview This course will provide training in genome editing and cell engineering in mammalian cells and mouse embryos using the highly efficient CRISPR/Cas9 system. Participants will learn design of CRISPR targets using bioinformatics tools, generation of gene knock-outs/knock-ins, and target validation using the most current technologies. The course will be split into two groups (mammalian cells OR mice) based on participants’ expertise. Please note that all participants are expected to engage in all sessions. Participants should plan for approximately 1 hour extra per day for self paced learning modules. Audience This course is aimed at researchers who are familiar with basic molecular and cell biology techniques and who want to learn how to create an engineered mammalian cell...

EMBL Course

EMBL Heidelberg

Registration
09 June 2024

2 September - 5 September 2024

Imaging mouse development

2 September 20242024ConferenceEMBL Heidelberg, Virtual

Jan Ellenberg, Kate McDole, Isabel Espinosa Medina, Robert Prevedel, Shankar Srinivas

OverviewSpeakersPreliminary ProgrammePractical informationSponsorsMedia kit Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Conference overview This workshop aims to bring together and help establish an emerging community with the common goal of four dimensional reconstruction of mammalian development A number of long standing... OverviewSpeakersPreliminary ProgrammePractical informationSponsorsMedia kit Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Conference overview This workshop aims to bring together and help establish an emerging community with the common goal of four dimensional reconstruction of mammalian development. A number of long­standing questions surrounding the early development of mammals have been inaccessible to molecular research due to technical limitations and poor physical accessibility of these processes. How is the body plan established in the early embryo? How is morphogenesis coordinated with lineage specification? The recent revolutions in advanced light microscopy and bioimage informatics have opened up completely new avenues to address these questions and make fundamental advances in our understanding of the developing mammalian...

EMBO Workshop

EMBL Heidelberg, Virtual

Registration (Virtual)
26 August 2024
Registration (On-site)
22 July 2024
Abstract submission
10 June 2024

9 September - 12 September 2024

Chemical biology 2024

9 September 20242024ConferenceEMBL Heidelberg, Virtual

Yimon Aye, Bryan Dickinson, Maja Köhn

OverviewSpeakersPreliminary programmePractical informationSponsorsMedia kit Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Conference overview The conference sets the stage for the dissemination and exchange of new developments in diverse emerging fields within chemical biology It is the largest and longest standing conference in the... OverviewSpeakersPreliminary programmePractical informationSponsorsMedia kit Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Conference overview The conference sets the stage for the dissemination and exchange of new developments in diverse, emerging fields within chemical biology. It is the largest and longest-standing conference in the field, being a platform for inspiration, collaboration, and networking for researchers in academia and industry. We aim to provide the possibility for every chemical biologist to meet and discuss with peers topics ranging from tool development to biological applications, from computational protein design to new drug modalities. Session topics Chemical biology meets drug discovery Chemical biology of posttranslational modifications Non-coding RNA and unusual RNA products Lipids and lipidation Chemical...

EMBO Workshop

EMBL Heidelberg, Virtual

Registration (Virtual)
02 September 2024
Registration (On-site)
29 July 2024
Abstract submission
10 June 2024

9 September - 16 September 2024

Membrane protein expression, purification, and characterisation 3 (mPEPC3)

9 September 20242024CourseEMBL Hamburg

Maria Garcia Alai, Simon Mortensen, Kim Remans, Henning Tidow

OverviewSpeakers and TrainersProgrammeSponsorsMedia kitPractical information Overview Course overview This hands on course focuses on training participants on how to work with membrane proteins how to troubleshoot in the wet lab during solubilisation and reconstitution and how to conduct experiments at the beamlines and during early stages of cryoEM screening The presence of a... OverviewSpeakers and TrainersProgrammeSponsorsMedia kitPractical information Overview Course overview This hands-on course focuses on training participants on how to work with membrane proteins, how to troubleshoot in the wet lab during solubilisation and reconstitution, and how to conduct experiments at the beamlines and during early stages of cryoEM screening. The presence of a crystallisation and cryo-EM facility as well as beamlines for SAXS and for time-resolved macromolecular crystallography at the venue will be employed to perform integrated structural biology experiments. Audience Applicants in the early stage of their research careers (mid to end of PhD project or early postdoctoral career) will be given preference based on their application and letters of reference. We also welcome applications from non-academic labs. Modules Transient transfection of mammalian cells for...

Course

EMBL Hamburg

Registration
17 June 2024

15 September - 22 September 2024

Synthetic biology in action: engineering synthetic systems

15 September 20242024CourseEMBL Heidelberg, Virtual

Sven Panke, Vitor Pinheiro, Karen Polizzi, Nico Claassens, Velia Siciliano

OverviewSpeakersPreliminary ProgrammePractical InformationSponsorsMedia kit Overview Course overview Synthetic Biology SynBio has become a rapidly developing area for tackling a large number of challenges in life science research This is due to a combination of foundational advances in technologies such as large scale DNA synthesis and new methods that allow integrating such raw... OverviewSpeakersPreliminary ProgrammePractical InformationSponsorsMedia kit Overview Course overview Synthetic Biology (SynBio) has become a rapidly developing area for tackling a large number of challenges in life science research. This is due to a combination of foundational advances in technologies, such as large-scale DNA synthesis and new methods that allow integrating such raw synthesis power into engineering approaches. Those include genome wide small RNA regulation, dCas9-based regulation, and multiplexed genome engineering. Such fresh approaches fuel new types of biotechnological applications with immense impact on both fundamental science and society. This course will be offered in both onsite and virtual format, with different modules available to each format. It will provide the best and most exciting novelties in the field and focus on exploiting tools and concepts of SynBio...

EMBO Practical Course

EMBL Heidelberg, Virtual

Registration
23 June 2024

17 September - 20 September 2024

Reconstructing the human past: using ancient and modern genomics

17 September 20242024ConferenceEMBL Heidelberg, Virtual

Johannes Krause, Ida Moltke, Maanasa Raghavan, Pontus Skoglund

Combining genome wide data from ancient and modern populations opens new windows into the past Population scale sequencing projects investigating past and present human diversity have already provided us with extraordinary insights into patterns of human variation and mobility through time and space This meeting will involve scientists from population genetics bioinformatics microbiology anthropology archaeology and history and will strengthen future interactions in this young research field that is already changing the way we think about our past and will shape how we study genetic variation in the future... OverviewSpeakersPreliminary programmePractical informationSponsorsAboutMedia kit Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Symposium overview Combining genome-wide data from ancient and modern populations opens new windows into the past and, importantly, their integration with archaeological evidence and historical records elucidates aspects of human history and cultural evolution of past societies. Population-scale sequencing projects investigating past and present human diversity have already provided us with extraordinary insights into patterns of human variation and mobility through time and space. Moreover, genome-wide data from archaic human remains, such as Neandertals and Denisovans, allows to investigate human evolution in action and to provide direct insights into genetic changes that define our own lineage. The available...

EMBO | EMBL Symposium

EMBL Heidelberg, Virtual

Registration (Virtual)
10 September 2024
Registration (On-site)
06 August 2024
Abstract submission
18 June 2024

23 September - 27 September 2024

Metagenomics bioinformatics at MGnify

23 September 20242024CourseVirtual

Meredith Willmott

Learn about the tools processes and analysis approaches used by MGnify in the field of genome resolved metagenomics This course will cover the use of publicly available resources to manage share analyse and interpret metagenomics data focussing primarily on the assembly based approaches used in MGnify analysis The delivered content will involve participants learning via live lectures and presentations followed by live Q As with the trainers Practical experience will be developed in group activities and in computational exercises run using containerised tools on our training infrastructure This course is currently under development please check back again soon for further details... Learn about the tools, processes, and analysis approaches used by MGnify in the field of genome-resolved metagenomics. This course will cover the use of publicly available resources to manage, share, analyse, and interpret metagenomics data, focussing primarily on the assembly-based approaches used in MGnify analysis. The delivered content will involve participants learning via live lectures and presentations, followed by live Q&As with the trainers. Practical experience will be developed in group activities and in computational exercises run using containerised tools on our training infrastructure. This course is currently under development, please check back again soon for further details.

Course

Virtual

Registration
09 June 2024

23 September - 27 September 2024

Single-cell RNA-seq analysis with Python

23 September 20242024CourseVirtual

Juanita Riveros

This course covers the analysis of single cell RNA sequencing scRNA seq data using Python and command line tools Participants will be guided through droplet based scRNA seq analysis pipelines from raw reads to cell clusters You will explore and interpret single cell RNA seq data using Python as well as the Single Cell Expression Atlas Finally you will put their knowledge into practice through a group challenge on the last day Please note that you will not analyse your own data as part of the course There will however be ample opportunity to discuss your research and ideas with other course participants and trainers This course is currently under development please check back again soon for further details... This course covers the analysis of single-cell RNA sequencing (scRNA-seq) data using Python and command line tools. Participants will be guided through droplet-based scRNA-seq analysis pipelines from raw reads to cell clusters. You will explore and interpret single-cell RNA seq data using Python as well as the Single Cell Expression Atlas. Finally, you will put their knowledge into practice through a group challenge on the last day. Please note that you will not analyse your own data as part of the course. There will, however, be ample opportunity to discuss your research and ideas with other course participants and trainers. This course is currently under development, please check back again soon for further details.

Course

Virtual

Registration
09 June 2024

30 September - 3 October 2024

Defining and defeating metastasis

30 September 20242024ConferenceEMBL Heidelberg, Virtual

Eduard Batlle, Johanna Joyce, Daniel Klimmeck, Joan Massagué, Samra Turajlic

This symposium will bring together researchers from diverse fields to enhance our understanding of the dissemination and metastatic colonisation of tumour cells It will provide a unique opportunity for interdisciplinary exchange on current approaches and future collaborations on metastasis and its therapeutic challenges... OverviewSpeakersPreliminary programmePractical informationSponsorsAboutMedia kit Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Symposium overview In its second edition, this symposium will cover emerging key concepts of latent metastasis and dissemination of tumour cells including evolution and genetic diversity of metastasis, circulating tumour cells, stemness, dormancy and stromal reprogramming, transcriptional and epigenetic control, motility and invasive signalling, metastatic heterogeneity, EMT and plasticity, immune evasion, and metabolic adaptations. The meeting will provide a unique interdisciplinary exchange on current approaches and future collaborations on metastasis and its therapeutic challenges. Metastasis research is a nexus for several of the most exciting areas and technical developments of current cancer biology and...

EMBO | EMBL Symposium

EMBL Heidelberg, Virtual

Registration (Virtual)
23 September 2024
Registration (On-site)
19 August 2024
Abstract submission
08 July 2024

8 October - 11 October 2024

Molecular mechanisms in evolution and ecology

8 October 20242024ConferenceEMBL Heidelberg, Virtual

Gilles Fischer, Jordi van Gestel, Kimberley Kline, Sara Mitri, Antonis Rokas

This conference series has become known for exploring yeasts as models to study questions of general relevance to evolution and ecology Experts will speak on a range of topics including evolution theory ecology genetics cell biology genomics systems biology metabolic modelling and engineering... OverviewSpeakersPreliminary programmePractical informationSponsorsMedia Kit Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Conference overview Dramatic advances in omics technologies and genetic engineering now enable us to tackle one of biology’s most fascinating problems – how evolution works in life’s communities and ecosystems. Gaining mechanistic insights requires bringing together multiple disciplines and viewpoints. The focus of this workshop series is on interspecies and cell-environment interactions across living organisms, with a special focus on bacteria, microbial eukaryotes, and viruses. The workshop series aims to highlight the latest technological advances, amplify scientific and societal focus on biodiversity, and showcase studies on the vital role of microbes in planetary ecosystems. The 2024 meeting will bring together...

Conference

EMBL Heidelberg, Virtual

Registration (Virtual)
01 October 2024
Registration (On-site)
27 August 2024
Abstract submission
10 July 2024

13 October - 18 October 2024

Metabolite and species dynamics in microbial communities

13 October 20242024CourseEMBL Heidelberg, Other

Sunil Laxman, Kiran Patil, Elisabeth Zielonka, Maria Zimmermann-Kogadeeva

The main goal of the course is to equip the participants with the state of the art concepts in microbial ecosystems and introduce them to the key tools towards gaining mechanistic insights in community dynamics... OverviewSpeakersPreliminary programmeSponsorsMedia kit Overview Course overview Metagenomics studies are rapidly uncovering the compositional richness of microbial communities in diverse habitats ranging from the oceans to the human gut. While their fundamental role in our health and environment is undeniable, there is an urgent need for unravelling molecular mechanisms underlying the dynamics of these communities. This requires a combined experimental and computational approach. Recent studies (including those from the organisers’ and speakers’ labs) have underlined the success of such integrative approaches. For example, emergence of cell subpopulations (Varahan et al. eLife 2019, 2020), and long-term stability (Blasche, Kim et al. Nat Microbiol. 2021) through metabolic cross-feeding. As researchers world-wide map species dynamics in the ecosystems of their interest, this course will...

EMBO Practical Course

EMBL Heidelberg, Other

Registration
22 July 2024

15 October - 18 October 2024

The complex life of RNA

15 October 20242024ConferenceEMBL Heidelberg, Virtual

Elena Conti, Olivier Duss, Torben Heick Jensen, Karla Neugebauer

This symposium brings together leaders in the RNA field post docs and students with the aim of disseminating and discussing the most recent findings of information added to mRNAs The programme will include among others sessions on transcription RNA processing and modification mRNA export and localisation mRNA surveillance and decay translation and the control of mRNA expression by microRNAs... OverviewSpeakersProgrammePractical informationSponsorsAboutMedia kit Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Symposium overview Before the genetic information stored in DNA can be used to direct cell growth and metabolism, it has to be transferred into RNA. Messenger RNAs (mRNAs) that code for proteins and noncoding RNAs are key components in the transmission of genetic information in all life forms – from viruses to complex mammalian organisms. Following the great success of the 2022 edition of this long-standing symposium, we are looking forward to returning in 2024, bringing together leaders in the RNA field, post-docs and students, with the aim of disseminating and discussing the most recent results. The programme will include topics on transcription, RNA processing and modification, mRNA export and localisation, mRNA...

EMBO | EMBL Symposium

EMBL Heidelberg, Virtual

Registration (Virtual)
08 October 2024
Registration (On-site)
03 September 2024
Abstract submission
23 July 2024

21 October - 26 October 2024

Imaging down to single-molecule resolution: STED & MINFLUX nanoscopy

21 October 20242024CourseEMBL Heidelberg

Clara Gürth, Marko Lampe, Julia Menzel, Sebastian Schnorrenberg

OverviewSponsorsSpeakersMedia kit Overview Registration is not yet open for this event If you are interested in receiving more information please register your interest Course overview The course aims to train biological microscopy users in two forms of super resolution light microscopy Stimulated Emission Depletion STED Microscopy and Minimal photon fluxes MINFLUX Both... OverviewSponsorsSpeakersMedia kit Overview Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Course overview The course aims to train biological microscopy users in two forms of super-resolution light microscopy, Stimulated Emission Depletion (STED) Microscopy and Minimal photon fluxes (MINFLUX). Both techniques require technical understanding of the process and instrumentation, training in the method specific requirements of sample preparation and in the acquisition procedures and an understanding of how to further analyze the acquired image data. It is the aim of the course to provide the tools for the successful execution of nanoscopy experiments with these two distinct methods. The course should also allow the participants to understand the specific benefits of the different techniques and thus help them in...

Course

EMBL Heidelberg

Registration
Will open shortly

29 October - 31 October 2024

Managing a bioinformatics core facility

29 October 20242024CourseEMBL-EBI

Sophie Spencer

This knowledge exchange workshop is an opportunity for managers of bioinformatics core facilities to learn from EMBL EBI s service teams and from each other These facilities play an essential role in enabling research in the molecular life sciences The landscape is constantly evolving as new research tools emerge as experiments become increasingly data intensive and as their clients experimental researchers become more exposed to the power of data driven biology This course will allow participants to share experiences discuss challenges and solutions that they face and plan ways to cope with the ever changing demands raised by the molecular life science field It will include sessions to learn from bioinformatics service providers hear how others have tackled common problems and work together to design core services resource them and measure their impact This course is currently under development please check back again soon for further details... This knowledge exchange workshop is an opportunity for managers of bioinformatics core facilities to learn from EMBL-EBI’s service teams, and from each other. These facilities play an essential role in enabling research in the molecular life sciences. The landscape is constantly evolving as new research tools emerge, as experiments become increasingly data-intensive, and as their clients – experimental researchers – become more exposed to the power of data-driven biology. This course will allow participants to share experiences, discuss challenges and solutions that they face, and plan ways to cope with the ever-changing demands raised by the molecular life science field. It will include sessions to learn from bioinformatics service providers, hear how others have tackled common problems, and work together to design core services, resource them, and measure their impact. This course is...

Course

EMBL-EBI

Registration
14 July 2024

4 November - 8 November 2024

The fundamentals of high-end cell sorting

4 November 20242024CourseEMBL Heidelberg

Beata Ramasz, Diana Ordonez

OverviewSpeakersPreliminary programmePractical informationSponsorsMedia kit Overview Course overview This course includes a robust theoretical part on the fundamentals of cell sorting delivered by world leading experts and practical sessions on using standard cuvette sorters In addition the course program will include principles applications and hands on sessions on Image Cell Sorting ICS... OverviewSpeakersPreliminary programmePractical informationSponsorsMedia kit Overview Course overview This course includes a robust theoretical part on the fundamentals of cell sorting delivered by world-leading experts and practical sessions on using standard cuvette sorters. In addition, the course program will include principles, applications, and hands-on sessions on Image Cell Sorting (ICS), allowing attendees to get in touch with this exciting technology! Audience The course is intended for Ph.D. students and postdocs who are starting to use or already using cell sorting in their research projects. Applicants with previous active knowledge of basic principles of flow cytometry and regular use of flow cytometers in daily research will profit most from the course content. Modules/Resources The topics that will be covered include; instrument set-up and validation, correct operation to...

EMBO Practical Course

EMBL Heidelberg

Registration
05 August 2024

4 November - 8 November 2024

Structural bioinformatics

4 November 20242024CourseVirtual

Juanita Riveros

This course provides a guide to the commonly used methods and tools in structural bioinformatics to analyse and interpret experimentally determined and AI predicted macromolecular structure data Structural biology determining the three dimensional shapes of biomacromolecules and their complexes can tell us a lot about how these molecules function and the roles they play within a cell Data derived from structure determination experiments and Artificial Intelligence AI assisted structure prediction enables life science researchers to address a wide variety of questions This course explores bioinformatics data resources and tools for the investigation analysis and interpretation of both experimentally determined and predicted biomacromolecular structures It will focus on how best to analyse and interpret available structural data to gain useful information given specific research contexts The course content will also cover predicting function and exploring interactions with other macromolecules This course is currently under development please check back again soon for further details... This course provides a guide to the commonly used methods and tools in structural bioinformatics to analyse and interpret experimentally determined and AI-predicted macromolecular structure data. Structural biology, determining the three-dimensional shapes of biomacromolecules and their complexes, can tell us a lot about how these molecules function and the roles they play within a cell. Data derived from structure determination experiments and Artificial Intelligence (AI)-assisted structure prediction enables life-science researchers to address a wide variety of questions.   This course explores bioinformatics data resources and tools for the investigation, analysis, and interpretation of both experimentally determined and predicted biomacromolecular structures. It will focus on how best to analyse and interpret available structural data to gain useful information given...

Course

Virtual

Registration
21 July 2024

5 November - 8 November 2024

DNA replication: from basic biology to disease

5 November 20242024ConferenceEMBL Heidelberg, Virtual

Anja Groth, Thanos Halazonetis, Helle Ulrich

OverviewSpeakersProgrammePractical informationSponsorsAboutMedia Kit Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Symposium overview There has been tremendous progress in the past few years regarding our understanding of DNA replication in eukaryotes both yeast and mammals Many important questions in the field are poised to be... OverviewSpeakersProgrammePractical informationSponsorsAboutMedia Kit Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Symposium overview There has been tremendous progress in the past few years regarding our understanding of DNA replication in eukaryotes, both yeast and mammals. Many important questions in the field are poised to be answered within the next decade. These include understanding DNA replication at the biochemical and three-dimensional protein structure levels. In addition, studies using high throughput technologies at the cellular and organismal levels are poised to answer how accurate replication of the genome is ensured by controlling origin firing in space and time. Session topics Replisome structure Origin selection, licensing and firing Chromatin replication Replication stress and fork stability Replication in cancer...

EMBO | EMBL Symposium

EMBL Heidelberg, Virtual

Registration (Virtual)
08 October 2024
Registration (On-site)
24 September 2024
Abstract submission
13 August 2024

14 November - 15 November 2024

The next generation in infection biology

14 November 20242024ConferenceVirtual

Maria Bernabeu, Jan Kosinski, Eva Kowalinski, John Lees, Lizette de Paula, Nassos Typas

Infectious diseases are among the most prevalent causes of human illness and death in the world Pathogens infect humans and all life forms on Earth being able to cross species barriers thereby adversely impacting human and planetary health Fundamental research in Infection Biology is urgently needed to find therapies for longstanding and emerging infectious diseases... OverviewPractical informationSponsorsMedia kit Overview Registration is not yet open for this event. If you are interested in receiving more information please register your interest. After the success of the virtual 2022 edition, this conference will return in a virtual format. Conference overview Infectious diseases are among the most prevalent causes of human illness and death in the world. Pathogens infect humans and all life forms on Earth, being able to cross species barriers, thereby adversely impacting human and planetary health. Fundamental research in infection biology is urgently needed to find therapies for longstanding and emerging infectious diseases.   The EMBL Conference ‘The next generation in infection biology’ is a platform for late-stage postdoctoral scientists in the field of infection biology to present their work and connect with the leading...

EMBL Conference

Virtual

Registration
Will open shortly

17 November - 22 November 2024

Humanized mice: immunotherapy and regenerative medicine

17 November 20242024CourseEMBL Heidelberg

Christian Münz, Jan Jacob Schuringa, Leonard Shultz, Brian Soper, Renata Stripecke, Anja Wege

OverviewSpeakersPreliminary programmeSponsorsMedia kit Overview Registration is not yet open for this event If you are interested in receiving more information please register your interest Course overview Humanized mouse models became an integral part of basic and translational biomedical research for the understanding of human pathologies and for development of new therapies Human... OverviewSpeakersPreliminary programmeSponsorsMedia kit Overview Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Course overview Humanized mouse models became an integral part of basic and translational biomedical research for the understanding of human pathologies and for development of new therapies. Human cells or tissues implanted in mice can reflect human hematopoiesis, immunity, oncology, infections, physiology and genetic polymorphisms. The development of immunotherapeutic drugs, cell and tissue therapies rely on the preclinical testing to assess their potency and safety. “Big pharma” and biotech companies include humanized mice in the non-clinical development portfolio. Humanized mouse models have varied among laboratories regarding the use of new transgenic and knock-out strains, improved handling...

EMBO Practical Course

EMBL Heidelberg

Registration
Will open shortly

17 November - 24 November 2024

Integrative structural biology: solving molecular puzzles

17 November 20242024CourseEMBL Hamburg

Arjen Jakobi, Jan Kosinski, Maya Topf

This practical course offers a hands on introduction to integrative structural biology Participants will delve into the fundamentals of various experimental structure determination techniques including X ray crystallography cryo EM small angle X ray scattering NMR and mass spectrometry through both lectures and practical exercises... OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Course overview Integrative structural biology has become a key strategy for determining the structure of biological macromolecules and their complexes. This method entails characterising the 3D structure through an array of complementary techniques, subsequently combining the data to form a consensus model using computational methodologies. This practical course offers a hands-on introduction to integrative structural biology. Participants will delve into the fundamentals of various experimental structure determination techniques including X-ray crystallography, cryo-EM, small-angle X-ray scattering, NMR, and mass spectrometry, through both lectures and practical exercises. Experts in the...

Course

EMBL Hamburg

Registration
Will open shortly

18 November - 22 November 2024

Plant genomes: from data to discovery

18 November 20242024CourseVirtual

Sophie Spencer

This course will take you through a selection of genomic tools and open resources to help you explore plant genomes Covering genomic genetic variation expression and protein data this course will show you where to find relevant data and how to use publicly available tools to connect across resources supporting plant genomic data driven knowledge discovery This course is currently under development please check back again soon for further details... This course will take you through a selection of genomic tools and open resources to help you explore plant genomes. Covering genomic, genetic variation, expression, and protein data, this course will show you where to find relevant data and how to use publicly available tools to connect across resources supporting plant genomic data-driven knowledge discovery.This course is currently under development, please check back again soon for further details.

Course

Virtual

Registration
04 August 2024

18 November - 22 November 2024

Genome bioinformatics: from short- to long-read sequencing

18 November 20242024CourseEMBL-EBI

Meredith Willmott

A guide to the technology analysis workflows tools and resources for next generation sequencing data analysis This course will provide insights and training into how biological knowledge can be derived from genomics experiments and explain different approaches in analysing such data The main focus will be on introducing sequence informatics re sequencing differences between short and long read sequencing and variant calling during the analysis of higher eukaryotes with an emphasis on human genetic research Throughout the week more advanced topics will introduce the creation of pipelines automation and the scaling up of analysis experiments Practical sessions will be run on datasets prepared by the trainers not on personal research data Participants will learn how to process these training datasets and to apply appropriate statistical methods in their analyses This course is currently under development please check back again soon for further details... A guide to the technology, analysis workflows, tools, and resources for next-generation sequencing data analysis. This course will provide insights and training into how biological knowledge can be derived from genomics experiments and explain different approaches in analysing such data. The main focus will be on introducing sequence informatics, re-sequencing, differences between short- and long-read sequencing, and variant calling during the analysis of higher-eukaryotes, with an emphasis on human genetic research. Throughout the week, more advanced topics will introduce the creation of pipelines, automation, and the scaling-up of analysis experiments. Practical sessions will be run on datasets prepared by the trainers, not on personal research data. Participants will learn how to process these training datasets and to apply appropriate statistical methods in their analyses....

Course

EMBL-EBI

Registration
04 August 2024

19 November - 22 November 2024

Quantitative biology to molecular mechanisms

19 November 20242024ConferenceEMBL Heidelberg, Virtual

Lacramioara Bintu, Hartland Jackson, Arnaud Krebs, Tineke Lenstra, Mikhail Savitski

OverviewSpeakersPractical informationSponsorsMedia kit Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Conference overview Recent decades have witnessed a profound transformation in molecular biology research fueled by revolutionary technologies that have greatly enhanced our ability to systematically and quantitatively measure... OverviewSpeakersPractical informationSponsorsMedia kit Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Conference overview Recent decades have witnessed a profound transformation in molecular biology research, fueled by revolutionary technologies that have greatly enhanced our ability to systematically and quantitatively measure biological molecules. The use of genomics, proteomics, and imaging have become routine, generating vast amounts of high-resolution data that characterise biological systems across multiple scales, ranging from molecules to organisms. This technological leap allows us to describe biological systems in quantitative terms with unprecedented resolution and provides a solid foundation for formulating mechanistic models that elucidate the intricacies of biological functions. ‘Quantitative biology to molecular...

Conference

EMBL Heidelberg, Virtual

Registration (Virtual)
12 November 2024
Registration (On-site)
08 October 2024
Abstract submission
27 August 2024

3 December - 6 December 2024

Hands-on course for sample preparation and data analysis in proteomics

3 December 20242024CourseEMBL Heidelberg

Mandy Rettel, Mikhail Savitski, Frank Stein

OverviewSpeakersPreliminary programmePractical informationSponsors Overview Registration is not yet open for this event If you are interested in receiving more information please register your interest Course overview The course will give an introduction to the theoretical aspects of the analysis of proteins peptides by mass spectrometry Participants will get hands on experience in... OverviewSpeakersPreliminary programmePractical informationSponsors Overview Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Course overview The course will give an introduction to the theoretical aspects of the analysis of proteins/peptides by mass spectrometry. Participants will get hands-on experience in sample preparation for a quantitative comparison across samples and perform a state of the art sample preparation and tandem mass tag labelling. Samples prepared by the participants will be measured by liquid chromatography-tandem mass spectrometry. In a session focused on bioinformatics analysis, participants will use FragPipe and FragPipe-Analyst in order to process the acquired data. Audience The course is intended for scientists that use or want to use proteomics for their research. Applicants should...

EMBL Course

EMBL Heidelberg

Registration
Will open shortly

24 February - 28 February 2025

Introduction to RNA-seq and functional interpretation

24 February 20252025CourseVirtual

EMBL-EBI Training

Gain an introduction to the technology data analysis tools and resources used in RNA sequencing and transcriptomics The content will provide a broad overview of the subject area and introduce participants to basic analysis of transcriptomics data using the command line It will also highlight key public data repositories and methodologies that can be used to start the biological interpretation of expression data Topics will be delivered using a mixture of lectures practical exercises and open discussions Computational work during the course will use small example data sets and there will be no opportunity to analyse personal data Virtual courseParticipants will learn via a mix of pre recorded lectures live presentations and trainer Q A sessions Practical experience will be developed through group activities and trainer led computational exercises Live sessions will be delivered using Zoom with additional support and asynchronous communication via Slack Pre recorded material may be provided before the course starts that participants will need to watch read or work through to gain the most out of the actual training event In the week before the course there will be a brief induction session Computational practicals will run on EMBL EBI s virtual training infrastructure meaning participants will not require access to a powerful computer or install complex software on their own machines Participants will need to be available between the hours of 09 00 16 00 hrs GMT each day of the course Trainers will be available to assist answer questions and provide further explanations during these times... Gain an introduction to the technology, data analysis, tools, and resources used in RNA sequencing and transcriptomics. The content will provide a broad overview of the subject area, and introduce participants to basic analysis of transcriptomics data using the command line. It will also highlight key public data repositories and methodologies that can be used to start the biological interpretation of expression data. Topics will be delivered using a mixture of lectures, practical exercises, and open discussions. Computational work during the course will use small, example data-sets; and there will be no opportunity to analyse personal data. Virtual courseParticipants will learn via a mix of pre-recorded lectures, live presentations, and trainer Q&A sessions. Practical experience will be developed through group activities and trainer-led computational exercises. Live sessions...

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Virtual

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18 March - 21 March 2025

Mechanisms of drug resistance and tolerance in bacteria, fungi and cancer

18 March 20252025ConferenceEMBL Heidelberg, Virtual

Judith Berman, Markus Ralser, Luiz Carvalho, Marina Rodnina

OverviewSpeakersSponsorsAboutMedia kit Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Registration is not yet open for this event If you are interested in receiving more information please register your interest Resilience to antimicrobial drugs is a rapidly increasing problem of global health Similarly cancer cells that become drug... OverviewSpeakersSponsorsAboutMedia kit Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Resilience to antimicrobial drugs is a rapidly increasing problem of global health. Similarly, cancer cells that become drug-resistant or tolerant affect therapy outcomes, for instance during cancer chemotherapy. The underlying biological mechanisms of tolerance, resistance, and persistence are increasingly being studied and reveal a complex interplay between (cellular) evolution, biochemistry, and metabolism. Understanding these mechanisms holds the long-term promise of developing new therapeutic strategies less prone to drug resistance and, in the short term, enhances our understanding of clonal evolution and single-cell...

EMBO | EMBL Symposium

EMBL Heidelberg, Virtual

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13 May - 16 May 2025

Chromatin and epigenetics

13 May 20252025ConferenceEMBL Heidelberg, Virtual

Asifa Akhtar, Amanda Fisher, Dirk Schubeler, Bing Ren

Epigenetics refers to heritable changes in gene expression that do not involve changes to the underlying DNA sequence At least three systems including DNA methylation histone modifications and non coding RNAs ncRNA are considered to play fundamental roles in epigenetic regulation Research over the last two decades has uncovered the role of epigenetics in a variety of human disorders and fatal diseases Moreover influence of age environment lifestyle and disease state on epigenetic states is being increasingly appreciated and actively studied This conference provides an international forum for cutting edge research in chromatin and epigenetics It provides the focal hub for people to present their research and exchange ideas in a virtual format Renowned speakers will cover the latest advances in the field... OverviewSpeakersSponsorsMedia kit Overview Registration is not yet open for this event. If you are interested in receiving more information please register your interest. This conference will take place at EMBL Heidelberg, with the option to attend virtually. Conference overview Epigenetics refers to heritable changes in gene expression that do not involve changes to the underlying DNA sequence. At least three systems including DNA methylation, histone modifications and non-coding RNAs (ncRNA) are considered to play fundamental roles in epigenetic regulation. Research over the last two decades has uncovered the role of epigenetics in a variety of human disorders and fatal diseases. Moreover influence of age, environment, lifestyle, and disease state on epigenetic states is being increasingly appreciated and actively studied. This conference provides an international forum for cutting...

EMBL Conference

EMBL Heidelberg, Virtual

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26 May - 28 May 2025

Infection: pathogens, hosts and microbiomes

26 May 20252025ConferenceEMBL Heidelberg, Virtual

Maria Bernabeu, Pascale Cossart,Hiten Madhani, Kim Orth, Michael Way

OverviewSpeakersSponsors Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Registration is not yet open for this event If you are interested in receiving more information please register your interest Infectious diseases are among the most prevalent causes of human illness and death in the world Epidemics pandemics have shaped human... OverviewSpeakersSponsors Overview This conference will take place at EMBL Heidelberg, with the option to attend virtually. Registration is not yet open for this event. If you are interested in receiving more information please register your interest. Infectious diseases are among the most prevalent causes of human illness and death in the world. Epidemics & pandemics have shaped human evolution and history, and although for a while there were considered a solved problem for the developed world, the recent past has showed us all why this is not the case. Antimicrobial resistance, global warming, human population size increase, modern lifestyles (urbanization, traveling), decrease of wild-life habitats for pathogen reservoirs all contribute to creating an ideal setting for infectious diseases becoming an even greater challenge in the future. This symposium will bring together experts...

EMBO | EMBL Symposium

EMBL Heidelberg, Virtual

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For past events see the archive.

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