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EMBL News archive

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10 September 2024 A brain section is seen in the background, from which a 'highway'emerges, with lit up neurons spaced like cars on the highway.

Follow the cellular road

Science & Technology An AI-enhanced advanced microscopy approach offers promise in better understanding glioblastomas, one of the deadliest brain cancers.

2024

science-technology

5 September 2024 Male scientist standing in front of a set of stairs.

Promoting impact-driven science

People & Perspectives PROMETHEUS is an EMBL-born grassroots initiative to promote and optimise impact-driven science.

2024

people-perspectives

4 September 2024

What I’ve learned: Alvis Brazma

People & Perspectives EMBL-EBI alumnus Alvis Brazma reflects on how mathematics and mountaineering have shaped his life and why keeping things simple in bioinformatics is key.

2024

people-perspectivesperspectives

30 August 2024 A multi-coloured donut representing the structure of an NPC.

“Structurally” sound

Science & Technology The function of biological molecules is intimately linked to their structure. In the 50 years since EMBL was established, its researchers and engineers have constantly provided leadership in structural biology research and services, resulting in many scientific breakthroughs and novel insights.

2024

science-technology

27 August 2024 In the foreground is a photoacoustic dye from the red end of the visible spectrum that is ‘turned on’. It produces an ultrasound emission that can be detected and measured. A dye that is ‘turned off’ is shown in the left background.

Seeing into the depths

Science & Technology EMBL scientists applied molecular engineering to build photoacoustic probes to label and visualise neurons deep within brain tissue.

2024

science-technology

23 August 2024

Welcome: David Ocaña

People & Perspectives EMBL-EBI’s new Head of Applications will use his expertise in cloud infrastructure and security to support the institute’s open data resources.

2024

people-perspectivesperspectives

21 August 2024 Three images of the cell at different stages of mitosis. In the left: round navy shape and irregular thick magenta line within it. In the middle: the same round shape with two irregular magenta shapes. On the right: Two round navy shapes connected with each other. Each of them holds shiny magenta-yellow clusters.

The forces behind chromosome repulsion and attraction during cell division

Science & Technology EMBL Heidelberg researchers discovered how a protein switches between repelling and gluing chromosomes during cell division. This helps the mother cell to divide the genome equally into two daughter cells and cluster chromosomes inside the daughter nuclei, ensuring a successful cell division.

2024

science-technology

16 August 2024 Two trucks with EMBL and TREC logos drive along a road next to the seaside, in the background are hills and houses from the suburbs of Athens.

TREC expedition concludes sampling in Greece

Connections The TREC expedition concluded its sampling in Greece and strengthened scientific exchange and collaborative networks with their Greek partners during a political and scientific stakeholder event in Athens.

2024

connections

14 August 2024

Merging passion, collaboration, and serendipity

People & Perspectives EMBL alumnus Thibaut Brunet, recipient of the 2024 John Kendrew Young Scientist Award, shares his scientific journey – from a childhood passion for nature to the discovery of a new species of choanoflagellate.

2024

people-perspectives

1 August 2024 Open Targets logo

Why clinical trials stop: the role of genetics

Science & Technology Using machine learning to analyse the genetic factors behind early clinical trial termination, researchers find a link between genetic evidence and trial outcome.

2024

research-highlightsscience-technology

31 July 2024 Silhouette of gastrointestinal track alongside an illustrator's representation of the carcinogens and antibiotics that seem to be affected by the gut microbiome

Gut microbes implicated in bladder cancer

Science & Technology Study shows that gut bacteria can metabolise carcinogens and cause them to accumulate in distant organs, leading to tumour development.

2024

science-technology

25 July 2024 Colourful arts and craft projects on a table

Science City Day at EMBL Hamburg

Lab Matters A major public engagement event at EMBL Hamburg attracted thousands. A video captures the spirit of the day from participants.

2024

lab-matters

24 July 2024

Sparking the next 50 years of collaborative discovery

Connections EMBL's 50th anniversary symposium brought together its vibrant community, showcased its many scientific contributions, and drove discussion on the future of Europe's leading life sciences laboratory.

2024

connections

10 July 2024

Leveraging expertise across EMBL services

Connections A scientific workshop on flow cytometry was organised at EMBL Rome, taking advantage of the presence of the Advanced Mobile Laboratory, the biggest unit of EMBL’s mobile lab fleet.

2024

connections

8 July 2024

EMBL Annual Report 2023 now online

EMBL Announcements EMBL’s 2023 Annual Report has been published, sharing achievements in its various missions, plus facts & figures from the year.

2024

embl-announcements

2 July 2024

Bulgaria becomes EMBL prospect member state

EMBL Announcements Bulgaria has become the latest EMBL prospect member state, starting a three-year process toward full membership. The prospect membership opens up new opportunities for mutual exchange and collaboration. Including Bulgaria, EMBL is now supported by 29 full member states, one associate member state,…

2024

embl-announcements

2 July 2024

IIT-EMBL: New molecules to modulate gene expression

Science & Technology A new research paper published in Nature Communications lays the groundwork for the development of new drugs specific to genetic mutations or alterations responsible for the onset of tumours or genetic diseases.

2024

science-technology

1 July 2024

EMBL celebrates 50 years of cutting-edge life science research

EMBL Announcements EMBL celebrates 50 years of cutting-edge European research: founded in Heidelberg by the first ten member states, Europe's pioneering Molecular Biology Laboratory (EMBL) is now supported by 29 member states and stands for outstanding open research, scientific services for researchers, innovative…

2024

embl-announcements

27 June 2024

Exploring microbial life in context

Science & Technology EMBL researchers and their partners have been studying microbial functions and interactions for the benefit of human and planetary health for the last two decades.

2024

science-technology

25 June 2024 In the front, a 3D model of three molecules bound together: METTL6 in (orange), serine tRNA synthetase in (shades of lilac) and serine tRNA (black). In the background an illustration of a construction site. Two trucks with ‘UGA’ and ‘AGA’ written on them are visible at the bottom.

An enzyme with a smart friend

Science & Technology EMBL Grenoble’s Kowalinski Group analysed the structure of an enzyme responsible for modifying tRNA molecules to fine-tune protein production. They discovered that to distinguish almost identical, yet different, tRNA molecules, the enzyme uses help from another enzyme – a type of cooperation…

2024

science-technology

21 June 2024

Welcome: Mallory Freeberg

People & Perspectives The new Team Leader for Human Genomics at EMBL-EBI shares how curiosity and maths shaped her career and what it takes to be a community builder.

2024

people-perspectivesperspectives

19 June 2024 In the centre: green angular origami-like shapes stacked on top of each other. Small orange rectangles akin to adhesive tape are placed where the green shapes connect with each other. In the background: a circle in the middle and cancer cells on the left and right.

‘Invisible’ protein keeps cancer at bay

Science & Technology EMBL Hamburg scientists and collaborators discovered a new molecular mechanism in which an unstructured protein disables one of the main cancer-promoting proteins by gluing them into an elongated stack. Data from human patient samples support the role of this mechanism in prostate cancer…

2024

science-technology

18 June 2024 A progression of three images against a blue/purple background. Each image shows a simulated mouse embryo inner cell mass with two types of cells marked in pink and green respectively. From the first to the third image, the pink cells slowly move from the outer edge to the inside of the mass.

Minecraft-ing our way into studying cell sorting

Science & Technology A theoretical model involving tiny Minecraft-like cubes can help us understand dynamic biological processes, such as cell sorting in embryos.

2024

science-technology

17 June 2024

TREC in Italy – sampling from coast to coast

Connections For almost two months, Italy was the stage for the TREC expedition, with a rich programme of events organised across the country attended by the public, scientists, schools, and high-level political stakeholders, including Minister of University and Research Anna Maria Bernini.

2024

connections

12 June 2024 A coffee mug on a table, with photographs nearby. The photos show pictures from the 1970s and 1980s, with a football team and a scientific research team represented.

Looking back: EMBL in the 1970s and 1980s

Lab Matters A special Coffee with EMBL session celebrated EMBL’s 50th anniversary by inviting alumni to reflect on the organisation’s first two decades.

2024

lab-matters

12 June 2024

AI approaches in structural biology and drug discovery

Connections EMBL Grenoble and the ESRF hosted a workshop bringing together representatives from research and industry to discuss the ever-growing role of artificial intelligence in the field of structural biology.

2024

connections

6 June 2024 A schematic of transport of dipeptides (white sticks) by the GLMP–MFSD1 complex. The transporter undergoes the common alternating access mechanism transitioning from outward-open conformation after dipeptide binding in the lysosomal lumen, to the occluded state where both sides of the binding site are closed, to the inward-open conformation enabling dipeptide release to the cytoplasm.

Structure and function of new lysosome transporter revealed

Science & Technology The group of Christian Löw at EMBL Hamburg and CSSB, and collaborators from the Christian-Albrechts-University Kiel and CNRS & Université Paris Cité worked together to reveal the structure and function of a previously unknown lysosome transporter, MFSD1.

2024

science-technology

29 May 2024 Two scientists stand in front of window, talking

12 moments of philanthropy: #5 Friends of EMBL

Connections Starting in 2014, Friends of EMBL engages a diverse range of individuals to support and connect with EMBL research. Through unique events and philanthropic contributions, members play a vital role in fostering a stronger bond between EMBL and society.

2024

connections

28 May 2024 An illustration of cells in a mosaic context, demonstrating the idea of genetic mosaicism in blood stem cells.

Genetic mosaicism more common than thought

Science & Technology Blood stem cells from healthy people carry major chromosomal alterations, a study in Nature Genetics by researchers at the Max Delbrück Center and the European Molecular Biology Laboratory (EMBL) finds. The discovery suggests that we are all genetic mosaics, which may contribute to ageing-related…

2024

science-technology

24 May 2024

Stephen Cusack: what I’ve learned

People & Perspectives Stephen Cusack, world-renowned structural biologist and former Head of EMBL Grenoble, reflects on his early influences, his achievements, and the lessons he’s learned as he embarks on his next adventure

2024

people-perspectives

22 May 2024 A sphere with two separated halves; the left half is blue and depicts chromosomes separating along spindles inside multiple nuclei, while the right half is orange, depicting a single set of chromosomes and a spindle with no nuclear envelope visible.

Exploring diversity in cell division

Science & Technology New research by EMBL scientists shows how different modes of cell division used by animals and fungi might have evolved to support diverse life cycles.

2024

science-technology

16 May 2024

Welcome: Julio Saez-Rodriguez

People & Perspectives EMBL-EBI's new Head of Research shares his plans and priorities.

2024

people-perspectivesperspectives

14 May 2024

Toby Gibson: what I’ve learned

People & Perspectives Toby Gibson reflects on 38 years at EMBL, the scientific tools he built along the way, and the state of science today.

2024

people-perspectives

9 May 2024

An epigenome editing toolkit to dissect the mechanisms of gene regulation

Science & Technology A study from the Hackett group at EMBL Rome led to the development of an epigenetic editing system that allows to precisely program chromatin modifications at any specific position in the genome, to understand their causal role in transcription regulation.

2024

science-technology

1 May 2024 Alt Text: An artistic representation of gut microbes and sperm cells

Father’s gut microbes affect the next generation

Science & Technology Scientists from EMBL Rome and EMBL Heidelberg found that disrupting the gut microbiome of male mice increases the risk of disease in their offspring. Their findings suggest that a father’s pre-conception environment can have lifelong effects on offspring.

2024

science-technology

30 April 2024 Colourful vertical panels each show different microscopic images possible with the high-tech tools in EMBL's Imaging Centre

12 moments of philanthropy: #4 EMBL Imaging Centre

Connections A bold vision to build a centre of excellence for imaging captured the imagination and support from private and public donors to help create the EMBL Imaging Centre.

2024

connections

30 April 2024 Open Targets logo

MSD joins the Open Targets consortium

EMBL Announcements MSD joins as the latest partner in the Open Targets consortium, enhancing the initiative’s collaborative efforts in drug discovery.

2024

announcementsembl-announcements

23 April 2024 This image showcases a processor with neon lights and abstract shapes that represent the flow and integration of spatial omics information. The background shows the analyzed and annotated breast cancer sample.

A universal framework for spatial biology

Science & Technology SpatialData is a tool developed by EMBL scientists in cooperation with multiple research institutions to unify and integrate data from different omics technologies in a spatial environment, providing holistic insights into health and disease. Researchers can now freely access and use SpatialData…

2024

science-technology

22 April 2024 A woman is looking through a book and checking a microscopy image on the screen of a laptop in front of her. On her left, there is the Curiosity microscope, which consists of grey, blue and yellow blocks connected with a red stripe.

Sparking curiosity: the Curiosity microscope

Lab Matters BIOcean5D is an EMBL-coordinated project co-funded by the European Union that unites 31 institutes to address pressing global challenges on marine biodiversity.

2024

lab-matters

18 April 2024 Group picture with a truck-size laboratory on wheels in the background

TREC sets off along the Mediterranean coast

Connections The second phase of the TREC expedition focuses on the Mediterranean coast, with Barcelona, Spain, hosting the first ‘superstop’ of 2024

2024

connections

8 April 2024 Artist’s stylised, semi-abstract representation of artificial intelligence

When AI meets biology

Science & Technology A recent EMBO | EMBL conference provided a forum for researchers to share how AI is making a difference in biology and bioinformatics.

2024

science-technology

4 April 2024

Building the cell’s splicing machine

Science & Technology New study from the Galej group provides deeper structural insight into the assembly of a critical molecular machine, that removes non-coding information from genes during their expression.

2024

science-technology

20 March 2024 4 people are standing in front of a man, Vladimir Benes, who speaks to them

Connecting shores and exploring new avenues for collaboration with Malta

Connections During a visit from high-level representatives of EMBL’s member state Malta, the honourable delegation allowed a peek behind the scenes of their scientific and institutional collaborations, and shared their memories and future aspirations for the partnership.

2024

connectionsevents

11 March 2024 Casting new light on gene regulation in development

Casting new light on gene regulation in development

Science & Technology New research from EMBL Heidelberg shows how cells in developing embryos undergo a major shift in the way they regulate gene expression as they mature and differentiate.

2024

sciencescience-technology

8 March 2024 Collage of six images showing scientists and science professionals during the TREC expedition, with a banner saying “International Women’s Day 2024” and the TREC expedition logo.

Insights and wisdom from the women of TREC

Lab MattersPeople & Perspectives On International Women’s Day 2024, we hear from some of the women who have been working tirelessly in the field and behind the scenes as part of the Traversing European Coastlines (TREC) expedition.

2024

lab-matterspeople-perspectives

6 March 2024 The background shows a render of a suspension of tumour cells, while an inset shows the structures of two proteins – MAGEA4 and RAD18 – marked in green and blue respectively

Studying the relationship between cancer-promoting proteins

Science & Technology A new study from the Bhogaraju Group at EMBL Grenoble reveals how the cancer-promoting MAGE family of proteins bind to their targets, aiding the development of anti-cancer drugs that target these proteins.

2024

sciencescience-technology

1 March 2024 Photographs of two male scientists in round insets against a decorative background

2024 EMBL Alumni Award recipients announced

EMBL Announcements Two former EMBL scientists have been recognised for their outstanding contributions to research and leadership capabilities in the fields of evolutionary cell biology and molecular medicine.

2024

alumniembl-announcements

19 February 2024 Collage of nine pictures with seven photographs showing expedition members sampling and engaging in public outreach activities, and two photos showing EMBL’s new mobile labs.

TREC in 2024: bringing it home

Science & Technology The Traversing European Coastlines (TREC) expedition prepares to begin its next phase of sampling, with stops in Spain, Greece, Italy, and beyond.

2024

sciencescience-technology

12 February 2024 Female scientist stands in front of white shelves filled with vials of fruit flies

Anne Ephrussi: what I’ve learned

Lab MattersPeople & Perspectives After 32 years at EMBL – leading a developmental biology research group and later simultaneously serving as EMBL’s Dean for its PhD programme, Anne Ephrussi has retired, ready to start her life’s next chapter.

2024

lab-matterspeople-perspectives

1 February 2024

We are EMBL: Renato Alves on Bio-IT and stargazing

Lab MattersPeople & Perspectives Renato Alves talks about his time at EMBL, the Bio-IT project, his wishes for EMBL in its anniversary year, and how a passion for night hikes and stargazing led to the creation of EMBL’s astronomy club.

2024

lab-matterspeople-perspectives

29 January 2024 Man leaning against a wall

Welcome: Kyle Morris

Lab MattersPeople & Perspectives Kyle Morris joins EMBL-EBI as Electron Microscopy Data Bank (EMDB) Team Leader.

2024

lab-matterspeople-perspectives

25 January 2024 An oval light blue shape. In the central part, there is a smaller a red object, from which stem many highly branched smaller canals that cover a significant part of the blue surface. The whole sponge image is in placed in a circle. The background around the circle is blue-green.

Ancient ‘relaxant-inflammatory’ response gets sponges moving

Science & Technology Sponges lack muscles and neurons. Yet, they make coordinated movements. Scientists at EMBL Heidelberg have discovered that sponge movement is controlled by an ancient ‘relaxant-inflammatory’ response that is also present in vertebrate blood vessels. The findings shed light on sponge physiology…

2024

sciencescience-technology

23 January 2024 Collage of EMBL historical photos with a 50-year anniversary logo

Reflections for the future during EMBL’s 50th anniversary year

Lab MattersPeople & Perspectives EMBL’s link to other sciences and its tradition of collaborative discovery carry on, providing the model and means to address big challenges, including climate change and biodiversity loss.

2024

lab-matterspeople-perspectives

9 January 2024 Latvian flag comprised of deep red with a horizontal white stripe across the center

Latvia becomes EMBL’s 29th member state

EMBL AnnouncementsLab Matters Latvia’s life sciences sector will benefit from expanded access to the leading European research, services, and training provided by EMBL.

2024

embl-announcementslab-matters

21 December 2023 On the left: image of a protein complex in a shape of a yellow doughnut with blue elements. Above it is a drawing of nucleic acid with arrows connecting nitrogenous bases to different points in the protein complex. On the right: a line with peaks indicating the peaks recorded in mass spectrometry. Above two peaks, there are smaller depictions of the doughnut-shaped complex, one with a blue element and one without.

RNA to rule them all

Science & Technology The Kosinski Group at EMBL Hamburg collaborated with other groups in Hamburg to reveal critical steps in Lassa virus ribonucleoparticle assembly and recruitment, and the crucial role played by RNA in in the Lassa virus life cycle.

2023

sciencescience-technology

19 December 2023 Cartoon showing nanoparticles on a conveyer belt passing through a machine. They are ordered by size and the smallest one pass through the machine before the bigger ones. A ray of light enters the machine, where a nanoparticle is being scanned, and leaves it on the other side. A monitor on top of the scanning machine shows an X-ray of a nanoparticle.

‘X-ray vision’ for investigation of mRNA nanomedicines

Science & Technology EMBL Hamburg, Johannes Gutenberg University Mainz, Postnova Analytics GmbH, and BioNTech SE have developed a new method to quantitatively investigate sizes of nanoparticles containing mRNA. It may become an important part of regular characterisation of mRNA nanomedicines in the future.

2023

sciencescience-technology

14 December 2023 Photo of Selina Storm standing in front of the PETRA III synchrotron storage ring.

We are EMBL: Selina Storm on PETRA IV and new perspectives for EMBL Hamburg

Lab MattersPeople & Perspectives EMBL Hamburg is located at the PETRA III synchrotron, which in the future, will be upgraded to PETRA IV. Selina Storm is theEMBL@PETRA IV Programme Manager. Here, she speaks about her role and the benefits of PETRA IV for EMBL.

2023

lab-matterspeople-perspectives

7 December 2023 Against blue and green background are two faux polaroids, one of an older man holding a coffee cup and the other a man in glasses

Navigating success: an EMBL alumni mentorship story

Lab Matters A recent success story of the Alumni Mentorship Programme is that of Luis Pedro Coelho, a Portuguese former postdoctoral fellow in the Bork Group, and his mentor Frank Gannon, former EMBO Director and EMBL Group Leader and Senior Scientist.

2023

alumnilab-matters

27 November 2023 A man and a woman looking at the camera, parts of a restaurant are visible in the background.

Exploring the universe: Roel Wijnaendts

People & Perspectives EMBL alumnus Roel Wijnaendts looks back at a long career in academic research and entrepreneurship that has left an indelible mark in the fields of instrumentation and optics.

2023

alumnipeople-perspectives

27 November 2023 Photo of two people brainstorming at the table covered with several papers and images related to the research project, such as the structure of the molecule, a map with the Solar Lake marked, photo of EMBL Hamburg, photo of Garo Antranikian looking into a microscope, pages of the manuscript, data graphs, and more.

Hamburg collaboration paves the way to cleaner technologies for industry

Science & Technology An interdisciplinary collaboration between Hamburg scientists has yielded new insights into the structure and function of a heat-resistant enzyme from an exotic microbe. In this interview, EMBL Hamburg’s Matthias Wilmanns and TUHH’s Garo Antranikian discuss how their collaboration developed and…

2023

sciencescience-technology

23 November 2023 Photographs of two scientists on a decorative background

ERC Consolidator Grants awarded to two EMBL researchers

EMBL AnnouncementsLab Matters Alba Diz-Muñoz and Arnaud Krebs from EMBL Heidelberg have received grants to work on projects that aim, respectively, to understand the cellular mechanics that control cell division and investigate the regulatory networks that govern transcription factor function.

2023

embl-announcementslab-matters

22 November 2023 Oliver Stegle passionately drawing work-related content with a green pen on a whiteboard. On the whiteboard, there are coordinates and equations, such as “n=2”.

How AI shapes the life sciences: an interview with Oliver Stegle

Lab MattersPeople & Perspectives EMBL scientist Oliver Stegle explains how AI-based tools have the potential to transform our ability to better understand the complexity of life and how these tools will shape the future of life science exploration.

2023

lab-matterspeople-perspectives

17 November 2023

TREC – Towards the end of the first phase

ConnectionsLab Matters The TREC expedition has come to the end of its first phase. The last superstop of 2023 was hosted by CIIMAR in Porto and, despite the adverse weather conditions, included many scientific and public engagement activities.

2023

connectionslab-matters

16 November 2023

EMBLetc. issue 101 published

EMBL AnnouncementsLab Matters The newest issue of our online magazine dives deep into a critical research direction in developmental biology, structures of promiscuous proteins, EMBL’s newest service offerings in field research, and much, much more.

2023

embl-announcementslab-matters

16 November 2023

New evidence on retinal function

Science & Technology A new study from the Asari group at EMBL Rome shows a different retinal function in awake mice compared to isolated retinal samples. These new insights could help to develop prosthetic devices that can act as a retina in the future.

2023

sciencescience-technology

15 November 2023 Group picture with mountain in the background

Looking back on 20 years of structural biology collaboration in Grenoble

ConnectionsLab Matters On this date (15 November), 21 years ago, the EMBL, ESRF, ILL, and IBS directors signed a memorandum of understanding to create the Partnership for Structural Biology (PSB) on the European Photon and Neutron (EPN) science campus in Grenoble.

2023

connectionslab-matters

14 November 2023 Blue thumbprint-sized ovals cluster together on a black background with white and pink dots sporadically situated on the blue ovals.

Five takeaways from ‘Seeing is believing’ in 2023

Science & Technology A recent EMBO | EMBL symposium brought together leading developers of imaging methods with cutting-edge applications that illustrate how imaging can answer biological questions.

2023

eventsscience-technology

7 November 2023

EMBL in Spain: Molecules to Ecosystems

Connections EMBL in Spain 2023 was held in Bilbao on Friday 9 October, hosted at the Center for Cooperative Research in Biosciences (CIC bioGUNE).

2023

alumniconnections

7 November 2023

Enjoying a science day in Grenoble

ConnectionsLab Matters EMBL Grenoble was once again present for the science outreach event ‘Parvis des Sciences’ on Saturday 14 October 2023.

2023

connectionslab-matters

1 November 2023 Sihyun Sung is standing next to experimental equipment for time-resolved serial X-ray crystallography. The light in the room is pink.

We are EMBL: Sihyun Sung on time-resolved structural biology

Lab MattersPeople & Perspectives In this interview, Sihyun Sung, Postdoctoral Fellow at EMBL Hamburg, talks about making molecular movies with time-resolved serial X-ray crystallography, his sources of inspiration, and the value of forging deeper connections with friends and colleagues.

2023

lab-matterspeople-perspectives

31 October 2023

EMBL’s southern hemisphere connection

ConnectionsLab Matters Ian Smith, Chair of EMBL Australia´s Council, chats about the synergies between the organisations, opportunities for collaboration, and ideas for exciting new programmes arising out of a recent visit to EMBL Heidelberg.

2023

connectionslab-matters

27 October 2023 The image shows a uerine environment made of a jelly-like and transparent material, with a cylindrical 3D structure.

Spotlight: Creating an artificial uterus

Science & Technology EMBL researchers have created an engineered uterus that allows a closer look at a mouse embryo’s development and its interactions with the uterine environment.

2023

picture-of-the-weeksciencescience-technology

26 October 2023 Photographs of three scientists on a decorative blue background

EMBL scientists receive prestigious ERC Synergy Grants

EMBL Announcements Jan Kosinski, Julia Mahamid, and Georg Zeller have received grants to enable ambitious projects aimed at mapping the cellular protein synthesis machinery in context and understanding complex host-microbiome interactions, respectively.

2023

embl-announcementsscience

26 October 2023

A promising target to fight inflammatory bowel diseases

Science & Technology Researchers from the Cusack group at EMBL Grenoble provide structural insights on the XIAP/RIPK2 complex, a promising drug target to fight inflammatory bowel diseases.

2023

sciencescience-technology

20 October 2023 Abstract art shows waves of yellow and green punctuated by pipe-like shapes poking out of the waves.

Six symposium takeaways about human microbiome research

Science & Technology Here are six takeaways from a recent EMBO/EMBL symposium that brought together scientists to discuss the state of research involving the human microbiome and its connection to health and disease.

2023

eventsscience-technology

18 October 2023 Female scientist looks directly at the camera, wearing blue jacket and white top

EMBL’s second Kafatos Lecture this Friday

EMBL Announcements Elena Conti will discuss how cells control the life and death of mRNA molecules at the 2023 annual Kafatos Lecture on 20 October in Munich.

2023

alumniembl-announcements

17 October 2023 Pill icons representing different antibiotic classes are seen exerting their effects on a bacterium, whose cell wall, membrane, and protein synthesis machinery (two different classes) can be seen as potential targets. Curved lines connect the pills to each other, representing synergies in drug interactions. More bacteria can be seen in the background.

Fighting antimicrobial resistance with new drug combinations

Science & Technology In an extensive investigation, EMBL researchers have tested over 10,000 drug combinations against some of the leading pathogenic bacteria carrying antimicrobial resistance and causing mortality. 

2023

sciencescience-technology

13 October 2023 Scientific illustration showing various model organisms used to study developmental plasticity and a series of concentric circles representing adaptability of interactions.

Understanding developmental plasticity in time and space

Lab MattersScience & Technology A two-week practical course introduced participants to the intricacies of studying the dynamic interplay between organisms and their changing environment and how it impacts development and evolution.

2023

lab-mattersscience-technology

9 October 2023

A night to share the wonders of science 

Lab Matters EMBL Rome celebrated the European Researchers’ Night by participating in an event organised at the CNR Campus in Montelibretti.

2023

lab-matters

6 October 2023

We are EMBL: Zuzana Koskova on her experience as a PhD student at EMBL Heidelberg

Lab MattersPeople & Perspectives Zuzana Koskova is a PhD student from Slovakia who, at the age of 19, left her country to pursue her career in biological sciences in Germany. In this interview, she talks about her interests, career aspirations, and recent participation at the Info Day held in Bratislava, where she had the…

2023

lab-matterspeople-perspectives

5 October 2023 A composite image of four 3D micrographs showing the cellular organelles of a phytoplankton marked in different colours.

Spotlight: Seeing into the seas

Science & Technology A new method developed by EMBL scientists can help us identify and investigate plankton species in field samples with greater speed, accuracy, and resolution than ever possible before.

2023

sciencescience-technology

2 October 2023 Outline of a human, purple against red background. Red RNA strand in the background, electrocardiogram across the image. On the right, outline of a Nobel prize medal.

mRNA nanomedicines scoop Nobel Prize in Physiology or Medicine

Science & Technology Pioneers of the mRNA nanomedicines technology receive 2023 Nobel Prize in Physiology or medicine. EMBL is pleased to have supported the development of the application of the mRNA nanomedicine technology through our long-standing collaboration with BioNTech, Johannes Gutenberg University Mainz and…

2023

sciencescience-technology

28 September 2023 Visual of AlphaFold Protein prediction, embedded into a visual of scientific data

EMBL receives German AI prize

EMBL Announcements EMBL receives the German AI prize awarded for outstanding services to the research and development as well as application and commercialisation of artificial intelligence (AI) in life science research.

2023

embl-announcementsscience

27 September 2023 A female scientist with shoulder-length hair and black shirt listens to a male scientist in burgundy shirt and white beard, seated to the right.

Five decades of EMBL visits

ConnectionsLab Matters Structural biologist Shlomo Trachtenberg has made research trips to EMBL from Israel since the late 1970s and reflects on the boost EMBL’s technology provided his research, the ingredients for an ideal research institution, and his ongoing fascination with microscopes.

2023

connectionslab-matters

21 September 2023

Understanding the mechanisms of enzyme catalysis

Science & Technology Enzymes constitute a large fraction of genomes – 20% in humans – which makes them a very important part of life. Despite decades of studies and a rich literature dedicated to understanding the reaction mechanisms of enzymes, the rules of enzyme catalysis are still not fully clear. A new…

2023

science-technologytechnology-and-innovation

21 September 2023 Group photo of the participants of the 12th annual meeting of the Nordic EMBL Partnership for Molecular Medicine in Espoo, Finland.

Forging collaborations across the Nordics

ConnectionsLab Matters The 12th annual meeting of the Nordic EMBL Partnership for Molecular Medicine took place in Espoo, Finland, between 11-14 September 2023.

2023

connectionslab-matters

21 September 2023 Man standing outside

Welcome: David Hulcoop

Lab MattersPeople & Perspectives David Hulcoop discusses how his experience bridging organisational cultures will help address critical challenges in drug discovery and target selection at Open Targets.

2023

announcementslab-matterspeople-perspectives

15 September 2023 Group of scientists attending symposium staring upward to the photographer.

Celebrating Stephen Cusack’s contributions to science

People & Perspectives Researchers from across the globe have gathered in Grenoble to celebrate the remarkable lifelong scientific achievements of Stephen Cusack, the former head of EMBL Grenoble.

2023

eventspeople-perspectives

15 September 2023

Switching off the cytokine storm

Science & Technology EMBL Grenoble and University of Geneva researchers shed light on the molecular activation of the MAP kinase p38α, the final ‘switch’ triggering the inflammatory response.

2023

sciencescience-technology

13 September 2023 Magenta and green sombrero-shaped object with grey lines beyond it sits against a black background

Understanding how cells avoid obstacles

Science & Technology EMBL researchers have identified a novel mechanism that allows cells to sense obstacles in their path and avoid them while navigating complex environments.

2023

sciencescience-technology

13 September 2023

Exploring Nexus Island

Lab Matters Learn more about the game-based workshop that lets participants experience what it feels like to be a researcher on the TREC expedition.

2023

lab-matters

8 September 2023 Female scientist looking into a microscope

TREC: Exploring the ocean’s oxygen supply

Lab MattersScience & Technology As part of the EMBL-led Traversing European Ecosystems (TREC) expedition, scientists are studying plankton to understand biodiversity, health, and our planet’s future.

2023

lab-mattersscience-technology

6 September 2023 A drawing of swordfish and a bubble containing a drawing of a molecular model. Both on blue background representing water.

Swordfish sword under X-rays: SAXS explained

Science & Technology Learn how scientists use bio-SAXS, an experimental X-ray technique, to study the shape and dynamics of proteins and other biomolecules. SAXS can be even used to analyse the structure of mineral particles in the swordfish sword bone, which can help scientists better understand bone ageing.

2023

sciencescience-technology

5 September 2023 Faces of Jordi van Gestel and Maria Zimmermann-Kogadeeva.

ERC starting grants for two EMBL Heidelberg researchers

EMBL AnnouncementsLab Matters Jordi van Gestel and Maria Zimmermann-Kogadeeva each receive 1.5 million EUR funding for research projects on microbial predators and the gut microbiome respectively

2023

embl-announcementslab-matters

31 August 2023 Part of a fruit fly embryo imaged against a dark background, with nuclei stained with DAPI (white), and a cluster of pole cells, marked by Vasa protein (yellow)

Spotlight: Off to the pole

Science & Technology For a fruit fly embryo to develop correctly, key factors need to get to the right place at the right time – a journey that starts in the developing egg, as seen in this image from the Ephrussi Group at EMBL Heidelberg

2023

picture-of-the-weeksciencescience-technology

24 August 2023 Set against a blue background, an illustration of a small paper shredder seemingly works at shredding mRNA, often in the form of origami shapes that float nearby.

Deciding when to destroy mRNA

Science & Technology Elena Conti will discuss how cells control the life and death of mRNA molecules at the next annual Kafatos Lecture on 20 October in Munich.

2023

alumniscience-technology

22 August 2023 Polaroid style shot of Sergiy Avilov, mentioning the years he was at EMBL

After EMBL: Sergiy Avilov

People & Perspectives Ukrainian scientist Sergiy Avilov uses the microscopy skills and scientific network he built at EMBL in his current role heading the Imaging Facility at the Max Planck Institute of Immunobiology and Epigenetics.

2023

alumnipeople-perspectives

18 August 2023 On green-hued multi-coloured background are four circle photographs of scientists working with high-tech equipment

Bringing scientific services together ‘2RISE’

Connections An upcoming EMBL-led infrastructure management training will help formalise information exchange in the Rhine-Neckar region to widen access to technology and scientific services for members of the Health + Life Science Alliance.

2023

connectionsevents

14 August 2023 Man standing in front of a building

Open data to power up the blue economy

People & Perspectives EMBL-EBI Senior Scientist Rob Finn explains why data coordination and sharing are fundamental for a sustainable blue economy.

2023

people-perspectivesperspectivesscience

8 August 2023 Clément Blanchet at the EMBL Hamburg’s P12 beamline’s experimental hutch.

Welcome: Clément Blanchet

Lab MattersPeople & Perspectives Clément Blanchet has been appointed to lead the team working on small-angle X-ray scattering (SAXS) at EMBL Hamburg. In this interview, he talks his ambitions for the future work of the SAXS Team, his passion for science, and a memorable ‘aha’ moment he had in his early career.

2023

lab-matterspeople-perspectives

3 August 2023 A male scientist working inside a trailer fitted with scientific instruments (left). On the right, the mobile lab trailer can be seen outside a large building in Sweden.

Bringing advanced life science technologies to the field

Lab MattersScience & Technology EMBL’s newly deployed Advanced Mobile Laboratory (AML) is bringing cutting-edge technologies to the European coast to help researchers study ‘life in context’.

2023

lab-mattersscience-technology

26 July 2023 Participants listen to the trainer in front of a screen displaying a microscopy image

Imaging-based spatial-omics: EMBO Practical Course at EMBL Rome 

Lab MattersScience & Technology The first EMBO Practical Course on imaging-based spatial-omics was organised at EMBL Rome to explore the latest techniques to visualise RNA transcripts and proteins in their native tissues.

2023

lab-mattersscience-technology

21 July 2023 Three-dimensional cartoon of the hexasome with a chromatin remodeler on DNA.

A glimpse into the hexasome: 40 years on

Science & Technology Research from the Eustermann group at EMBL Heidelberg reveals how the packaging of DNA into hexasomes impacts the function of enzymes involved in gene regulation.

2023

sciencescience-technology

10 July 2023 Green parasites on black background

Spotlight: Shedding light on deadly parasites

Lab MattersScience & Technology This single-celled organism the size of a dust particle is capable of causing deadly tropical diseases in both humans and livestock –Trypanosoma brucei, in an image by Luciano Dolce from EMBL.

2023

lab-matterspicture-of-the-weekscience-technology

7 July 2023 Cartoon of a molecule, formed by sticks and spheres.

Facilitating drug discovery against COVID-19

Science & Technology A collaboration between EMBL Grenoble and EBRIS scientists led to the characterisation of a new compound with promising activity against SARS-CoV-2 variants.

2023

sciencescience-technology

5 July 2023 Man standing in corridor

David Hulcoop appointed as Open Targets Director

EMBL Announcements Coming from a pharmaceutical industry background, David Hulcoop is set to take over as Executive Director of the public-private partnership Open Targets.

2023

announcementsembl-announcements

5 July 2023 Front page of annual report as shown on a tablet.

2022 EMBL Annual Report published

EMBL AnnouncementsLab Matters EMBL’s 2022 Annual Report is now available online, including a downloadable ‘Year in Review’.

2023

embl-announcementslab-matters

4 July 2023 Photos of the three scientists elected as EMBO members on green background.

EMBL scientists elected to EMBO Membership

Lab MattersPeople & Perspectives Three EMBL group leaders and six EMBL alumni were recognised for their contributions to the life sciences.

2023

lab-matterspeople-perspectives

4 July 2023 EMBL logo amended to note its upcoming 50th anniversary

Save the date: 4-5 July 2024!

EMBL Announcements EMBL will celebrate its 50th anniversary in 2024 with a dynamic scientific symposium. The event will share fundamental research that continues to open the way to scientific discoveries.

2023

embl-announcementsevents

3 July 2023 In the foreground: an intrinsically disordered protein, which has a form of a tangled, unstructured string. In the background: a set of parallel curved lines.

Bringing research on disordered proteins to order

Science & Technology A third of all known proteins are either completely or partially unstructured. EMBL scientists contributed to a new set of guidelines – Minimum Information About a Disorder Experiment (MIADE) – that will help researchers share data on unstructured proteins in a more useful way and will enable…

2023

sciencescience-technology

28 June 2023 Serbian flag

Serbia becomes EMBL prospect member

EMBL AnnouncementsLab Matters Starts three-year process toward full membership, opening up new opportunities for mutual exchange and collaboration.

2023

embl-announcementslab-matters

28 June 2023 Female scientist in white lab coat enjoying camaraderie of colleagues.

After EMBL: Urtė Neniškytė

People & Perspectives EMBL Rome alumna Urtė Neniškytė returned to her native Lithuania, helping establish the Vilnius University-EMBL Partnership Institute and advance genome-editing technologies there.

2023

alumnipeople-perspectives

26 June 2023

Connecting scientists, engaging citizens

ConnectionsLab Matters The TREC expedition stop in Sopot offered an opportunity to create connections with Polish scientists and citizens around the topics of planetary biology and ocean science.

2023

connectionslab-matters

22 June 2023 Woman stands in front of railing.

Welcome: Sihem Bennour

Lab MattersPeople & Perspectives Sihem Bennour, new head of HR, foresees a deeper culture of information sharing, listening, and problem solving with EMBL staff.

2023

lab-matterspeople-perspectives

13 June 2023 The conference brought together multiple disciplines from around the world to talk about life in context. Credit: EMBL creative team

An organisation and its environment

Science & Technology A recent EMBL conference brought together scientists from various disciplines to conjoin scientific pursuits studying ‘life in context’.

2023

eventsscience-technology

29 May 2023 group photo of the workshop participants

EMBL and SciLifeLab cooperate on data science

ConnectionsLab Matters The third meeting between EMBL and SciLifeLab communities took place in Uppsala and focused on data science, aiming at further expanding the collaboration

2023

connectionslab-matters

26 May 2023 Female scientist in white lab coat is showing material in a petri dish to EC official in lab coat

Sharing knowledge, widening access across Europe

ConnectionsLab Matters European Commission and EMBL renew commitment, agree on new areas of cooperation, in new EC DG’s first infrastructure visit since appointment.

2023

connectionslab-matters

25 May 2023 Close-up photo of a mother and father with their two young daughters

After EMBL: Heiko Runz and Laurence Ettwiller

People & Perspectives From biking together while at EMBL to assistant professorships at Heidelberg University, two academics soon formed a union that took them to the United States., into various industry positions, and now to a life with two young children.

2023

alumnipeople-perspectives

15 May 2023 Science illustration representing research on organoids, organs-on-chip and human health. The image shows an abstract composition of several elements referring to the tools and some areas of research covered at EMBL Barcelona, featured on the cover of the 100th issue of EMBL etc.

100th issue of EMBLetc. published

EMBL AnnouncementsLab Matters First published in 1999 as a black-and-white printed newsletter for EMBL staff and alumni, EMBLetc. has undergone many transformations in its 24 years of existence.

2023

embl-announcementslab-matters

11 May 2023 An colourful image taken from the World of Molecular Biology exhibition.

The World of Molecular Biology is open 

EMBL AnnouncementsLab Matters EMBL´s new permanent exhibition ‘The World of Molecular Biology’ in Heidelberg is now open for registration. The exhibition takes the visitor on a journey of scales, from genomes to ecosystems, and introduces key imaging technologies.

2023

embl-announcementslab-matters

10 May 2023 Globe with genome data from multiple people

A more diverse human reference genome

Science & Technology The human pangenome – one of the most complete collections of genome sequences released so far – captures rich human diversity.

2023

announcementssciencescience-technology

10 May 2023 Illustration showing a cute humanoid-shaped robot that spits pink droplets at a sheet.

Time-resolved crystallography for the masses

Science & Technology EMBL Hamburg scientists have contributed to the development of the Spitrobot, a ground-breaking experimental setup that will simplify creating molecular movies. The Spitrobot automates the sample preparation for time-resolved crystallography, which is used to create 3D snapshots of protein…

2023

sciencescience-technology

4 May 2023 Man stands in front of board listing corporate partner names

Vizgen joins EMBL science-industry programme

ConnectionsLab Matters Vizgen, the life science company dedicated to improving human health by visualising single-cell spatial genomics information, has joined EMBL’s Corporate Partnership Programme.

2023

connectionslab-matters

28 April 2023 two students wear virtual reality headsets

Building a broader European science community

ConnectionsLab Matters Croatian scientists and students from the Ruđer Bošković Institute and University of Zagreb visited EMBL to exchange ideas with researchers and public outreach experts on ways to increase interest, awareness, and involvement in science.

2023

connectionslab-matters

28 April 2023 Group photograph of people facing the camera holding certificates.

EMBL celebrates 43 new PhDs

Lab Matters On Friday 21 April 2023, EMBL held a graduation ceremony to celebrate its newest group of PhDs who graduated during the last 12 months. The graduating class comprised 43 fellows representing 17 nationalities and all six EMBL sites.

2023

eventslab-matters

20 April 2023 Photo of a human hand introducing a small element into a machine at the SPC Facility.

EMBL Hamburg joins northern European life science consortium

ConnectionsLab Matters EMBL Hamburg partners with the Hanseatic Life Science Research Infrastructure Consortium (HALRIC) to enhance life sciences research in Scandinavia and northern Germany. The consortium builds on the HALOS project to foster collaborations between industry, hospitals, and universities, leveraging…

2023

connectionslab-matters

20 April 2023 White woman with short red hair standing in garden in front of a tree. Picture of Angelika Thomasson. Credits: Marcos Lopez-Marrero/EMBL

We are EMBL: Angelika Thomasson on administrative support to EMBL staff

Lab MattersPeople & Perspectives Angelika Thomasson, administrative assistant at EMBL Grenoble, talks about her role in supporting her colleagues in organising events and travels, what she enjoys about EMBL, and which famous female scientist she would like to have coffee with.

2023

lab-matterspeople-perspectives

18 April 2023 Decorative image showing WormBase ParaSite logo

WormBase ParaSite 18 released

Science & Technology WormBase ParaSite release 18 adds largest number of new genomes and annotations since launch, as well as full integration with AlphaFold.

2023

science-technologyupdates-from-data-resources

17 April 2023 Photo of EMBL alumni in current lab in Spain

After EMBL: Thomas Graf

People & Perspectives Alumnus Thomas Graf reflects on his time at EMBL, offering an update on his whereabouts and advice for young scientists.

2023

alumnipeople-perspectives

12 April 2023 Photo of Eduard Avetisyan smiling and standing next to the servers at EMBL Hamburg.

We are EMBL: Eduard Avetisyan on the role of IT in structural biology

Lab MattersPeople & Perspectives Eduard Avetisyan leads the EMBL Hamburg IT team. He joined EMBL after transitioning from particle physics research to IT. Besides providing standard IT user support, his team also enables smooth processing and computational analysis of structural biology data. Here, he talks about the joys and…

2023

lab-matterspeople-perspectives

11 April 2023 Phylogenetic tree with beams of light to represent data

MAPLE: a phylogenetic tool for pandemic-scale genome data

Science & Technology EMBL-EBI researchers have developed a new tool capable of performing state-of-the-art phylogenetic inference on larger datasets than previously thought possible.

2023

research-highlightssciencescience-technology

11 April 2023

EMBL and Montenegro: boosting cooperation and enhancing awareness

ConnectionsLab Matters Europe’s life sciences laboratory EMBL on 5 April welcomed Council delegates Ivana Lagator and Lidija Vukcevic from the Montenegrin Ministry of Science and Technological Development, and University of Montenegro representative Professor Danilo Mrdak, to discuss expanding research and training…

2023

connectionsembl-member-stateslab-matters

4 April 2023 A mobile lab on a road, with the TREC logo on the side.

TREC is underway!

EMBL Announcements EMBL’s planetary biology flagship TREC expedition has officially started. The new project applies EMBL's expertise and technologies in molecular and cellular biology to current environmental challenges, and connects with a wide range of research disciplines.

2023

embl-announcementseventsscience

4 April 2023 Title slide for the conference, The organism and its environment

Life in context

Science & Technology Upcoming EMBO/EMBL symposium provides a forum to explore how organisms function together, and how they react or adapt to changes at different molecular levels.

2023

eventsscience-technology

3 April 2023 Two male scientists with safety glasses at EMBL Imaging Centre

Dispensing microscopy expertise

Lab MattersScience & Technology Home to some of Europe’s most cutting-edge tools in molecular biology, EMBL has long shared its expertise and access to these tools through an extensive repertoire of courses, conferences, seminars, and other training. And now included in this mix is a job shadowing programme at EMBL Imaging…

2023

lab-mattersscience-technology

30 March 2023 Science illustration representing two embryos imaged using the Brillouin microscopy technique. The embryo in the front is a mouse embryo at 20h and the one in the back a Phallusia mammillata embryo. A laser beam crosses the samples to analyse tissue stiffness (here represented by acoustic waves).

Shining light on the mechanics of embryo development

Lab MattersScience & Technology A new microscope built by EMBL researchers, based on Brillouin scattering principles, allows scientists to observe the dynamics of mechanical properties inside developing embryos in real time.

2023

lab-matterssciencescience-technology

30 March 2023 Profile picture of Cornelius Gross, interim head of EMBL Rome

ERC Advanced Grant awarded to EMBL Rome researcher

EMBL AnnouncementsLab Matters Interim head of EMBL Rome Cornelius Gross has been awarded an Advanced grant from the European Research Council (ERC) for his project TERRITORY, aimed at investigating the neural basis of territorial aggression and fear.

2023

embl-announcementslab-matters

23 March 2023 Portrait of a person looking at the camera. In the background there are trees and a white building

Welcome: Alejandro Torres-Sánchez

Lab MattersPeople & Perspectives The new group leader is setting up the first purely theory-focused research group at EMBL Barcelona. He aims to understand fundamental biological principles using mathematical models and computer simulations, in close collaboration with experimental researchers across EMBL.

2023

lab-matterspeople-perspectives

21 March 2023 Male scientist in blue shirt standing in front of a building with glass doors.

Welcome: Thomas Quail

Lab MattersPeople & Perspectives New group leader Thomas Quail studies the fundamental processes that determine how proteins organise the genome inside a cell.

2023

lab-matterspeople-perspectives

20 March 2023 Team leader Gergely Papp.

Welcome: Gergely Papp

Lab MattersPeople & Perspectives Together with his team, Gergely Papp pushes the frontiers of technology development in the field of structural biology.

2023

lab-matterspeople-perspectives

17 March 2023 Liz Duke standing on the left side of the photo, with EMBL Hamburg's P14 beamline and a big screen on the right.

Molecules to Ecosystems: Liz Duke on X-ray imaging

Lab MattersPeople & Perspectives Biological X-ray imaging is an emerging technology that uses X-rays to image tissues or even entire organisms. It will play an important role in EMBL Hamburg’s future service portfolio, and will allow studying life on multiple scales. Team Leader Liz Duke discusses her plans to establish X-ray…

2023

lab-matterspeople-perspectives

15 March 2023 Image of a group of people behind a large, black table with two cakes on it to celebrate EMBL Barcelona’s fifth anniversary

EMBL Barcelona: Five years down the road

Lab Matters EMBL’s site by the sea completed its fifth year of operations. We look back at some key milestones and achievements since 2017.

2023

lab-matters

7 March 2023 Black and white photograph showing a group of scientists standing in frnot of a building.

Tracing the history of women in science at EMBL

Lab Matters On the occasion of International Women’s Day 2023, EMBL archivist Maria Papanikolaou discusses the traces left by the women in science who have passed through EMBL, irrevocably changing the organisation in small and big ways.

2023

lab-matters

1 March 2023 Moisés Bueno is standing next to the transfer robot. The robot has a form of a yellow robotic arm on a stand. Behind is the CrystalDirect™ Harvester, which is a white cuboid with two transparent dimmed windows for laser protection.

Biology meets engineering

Lab MattersScience & Technology Physicists, engineers and robotics experts work together in EMBL Hamburg’s Instrumentation Team to design instruments that support structural biology research. The team has finished a transfer robot that facilitates automated handling of protein crystals with care and precision. This will help…

2023

lab-mattersscience-technology

23 February 2023 Image showing the pulsed green laser exciting the photoacoustic signal of the sample in the cuvette.

Spotlight: Using light and sound to see into the brain

Lab MattersScience & Technology Researchers in the Prevedel Group use photoacoustic spectroscopy setup to test and optimise probes before their usage in mouse neuroscience.

2023

lab-matterspicture-of-the-weekscience-technology

20 February 2023 The Estonian flag

EMBL welcomes Estonia as full member

EMBL AnnouncementsLab Matters The Baltic nation of Estonia has become a full member of EMBL, joining the organisation as its 28th member state.

2023

embl-announcementslab-matters

16 February 2023

New EU-funded Project: Fragment-Screen

Lab MattersScience & Technology EMBL is one of the partners of this project that aims to accelerate drug discovery and development, bringing in expertise from EMBL Grenoble and EMBL-EBI.

2023

lab-mattersscience-technology

15 February 2023 A photo of a scientist operating one of the instruments at the EMBL SPC Facility.

Supporting scientists across Europe: the SPC Facility at EMBL Hamburg

Lab MattersScience & Technology EMBL Hamburg’s Sample Preparation and Characterisation (SPC) Facility offers scientists access to almost all available biophysics technologies. The facility’s staff provides advice and support with experiments and data analysis. The facility is conveniently located just next to the EMBL…

2023

lab-mattersscience-technology

13 February 2023 Female scientist stands in front of lab bench

Welcome: Hanh Vu

Lab MattersPeople & Perspectives Group Leader Hanh Vu studies ‘immortal’ flatworms that can grow and de-grow to understand better factors that determine organisms’ sizes.

2023

lab-matterspeople-perspectives

11 February 2023 Female student stands in front of a lab bench

Scientific passion that seeds passion

Lab Matters A recent student visitor shares her impressions from visiting EMBL’s Vincent group as we recognise International Day of Women and Girls in Science.

2023

lab-matters

7 February 2023 BII and EMBL logos are on a white band set against a wavy green background

Promoting European innovation in the life sciences

ConnectionsLab Matters One of EMBL’s core missions is the development and transfer of scientific know-how and technologies to academia, industry, and commercial entities to facilitate further research, innovations, and commercialisation for the benefit of society at large. Working across Europe, EMBL has partnerships…

2023

connectionslab-matters

31 January 2023

ERC Consolidator Grant success at EMBL

EMBL AnnouncementsLab Matters EMBL Rome group leader Jamie Hackett receives EUR 2 million for the ModLogic project, aimed at understanding how chromatin modifications impact gene activity.

2023

embl-announcementslab-matters

25 January 2023 A group photo from the BiOcean5D launch meeting

BIOcean5D targets marine biodiversity

ConnectionsLab Matters EMBL hosts inaugural meeting for major interdisciplinary project designed to boost understanding of ocean life

2023

connectionslab-matters

20 January 2023 bright yellow and striped flatworms

Spotlight: A ‘devil’ of a flatworm

Lab MattersScience & Technology Tasmanian flatworms add to an EMBL researcher’s collection as she studies principles that control animal body size.

2023

lab-matterspicture-of-the-weekscience-technology

19 January 2023 Cross sections of mouse colon, with mucus stained in blue and nuclei stained in red. The right section has been treated with a mucolytic agent.

Spotlight: Colours of the colon

Lab MattersScience & Technology Mucus present in the mouse colon can be visualised using Alcian blue staining, as imaged here by EMBL predoctoral fellow Linda Decker.

2023

lab-matterspicture-of-the-weekscience-technology

9 January 2023

New molecular insights on medical cannabis

Science & Technology EMBL Grenoble researchers have investigated the interaction between THC and some proteins it might bind to. In a recent study, they showed in vitro that THC inhibits an important human enzyme called autotaxin.

2023

sciencescience-technology

4 January 2023 Confocal microscopy of dynamic concentration of nucleoporins (top) and 3D model of postmitotic assembly pathway of the nuclear pore complex over a time scope of 60 minutes during cell division.

Step-by-step guide to nuclear pore complex assembly

Science & Technology EMBL Heidelberg researchers and their collaborators reveal how the nuclear pore complex, one of the biggest molecular machines in eukaryotic cells, is assembled one protein at a time.

2023

sciencescience-technology

23 December 2022 Several zebrafish embryos in different colours during gastrulation

Spotlight: Zebrafish embryos to make this season jolly

Lab MattersScience & Technology Zebrafish embryos during gastrulation, a very early stage of development, to study the effect of temperature on vertebrate embryo development.

2022

lab-matterspicture-of-the-weekscience-technology

12 December 2022 A mother and her child looking through a microscope

Celebrating science in Grenoble

ConnectionsLab Matters In October 2022, EMBL Grenoble participated in the annual science outreach event Parvis des Sciences, organised by the GIANT campus under the umbrella of the French science week – La Fête de la science.

2022

connectionslab-matters

8 December 2022 Image of Prof. Peter B. Becker in the laboratory

New chair of EMBL Council

EMBL AnnouncementsLab Matters EMBL alumnus and eminent molecular biologist Peter B. Becker has been named the next chair of EMBL’s Council as of January 2023.

2022

embl-announcementslab-matters

7 December 2022 Two scientists in a lab conversing

Making a great postdoc program even better with our member states

EMBL AnnouncementsLab Matters EMBL’s EIPOD-Learning in Context programme focuses on interdisciplinary research that explores ‘life in context’ and adds a new collaborative dimension with member state organisations.

2022

embl-announcementslab-matters

1 December 2022

Getting closer to stopping toxoplasmosis infection

Science & Technology Recent studies supported by EMBL Grenoble’s expertise in structural biology research and scientific services have identified Altiratinib as a potential drug to stop toxoplasmosis infection and opened up treatment options against malaria.

2022

sciencescience-technology

30 November 2022 Portrait of Talya Dayton propped up on a balcony rail

Welcome to EMBL: Talya Dayton

Lab MattersPeople & Perspectives The new group leader in Barcelona aims to understand how cells behave in health and in disease, and approaches her favourite hobby, cooking, very similarly to her work in the lab.

2022

lab-matterspeople-perspectives

22 November 2022 Image portraying the three scientists who received the ERC Starting grant

EMBL scientists receive prestigious ERC Starting Grant

EMBL AnnouncementsLab Matters Three EMBL scientists received this year’s ERC Starting Grants, and will be awarded €1.5 million over five years to carry out research projects.

2022

embl-announcementslab-matters

21 November 2022 male scientist in green shirt and dark pants stands outside in front of tree

Welcome Jordi van Gestel

Lab MattersPeople & Perspectives Looking to understand microbial predator-prey relationships, EMBL’s newest group leader tackles a molecular ‘arms race’ in his lab.

2022

lab-matterspeople-perspectives

18 November 2022 A molecular illustration in the background showing ribosomes inside a Mycoplasma cell. A banner on top reads 'EMBLetc. Issue 99'

EMBLetc. receives digital-first makeover

EMBL AnnouncementsLab Matters The biannual magazine that highlights EMBL’s research, people, and projects now has a new online home.

2022

embl-announcementslab-matters

3 November 2022 View from above of a small room with several tools, cables and pieces of technology. A rectangular box, a robotic arm and a device are highlighted in green.

Two in one: combining MASSIF-1 and CrystalDirect

Lab MattersScience & Technology Researchers and engineers have integrated a CrystalDirect harvester into the fully automated beamline MASSIF-1, a unique combination of structural biology technologies that is now open to external academic users.

2022

lab-mattersscience-technology

27 October 2022 Male scientist looking towards the camera, against a blurred background

Setting priorities for preprints and open science

Lab MattersPeople & Perspectives Newly appointed member of the ASAPbio Board of Directors, EMBL Group Leader Gautam Dey speaks about preprints, data management, and open science.

2022

lab-matterspeople-perspectives

21 October 2022 A female scientist in a blue dress stands in front of blurred woodsy background

Welcome: Flora Vincent

Lab MattersPeople & Perspectives After a postdoc at Weizmann Institute of Science in Israel, Flora Vincent has joined EMBL’s Developmental Biology unit to further explore the world of phytoplankton.

2022

lab-matterspeople-perspectives

20 October 2022 Two EMBL staff members looking at a piece of equipment

Teaming up to drive forward time-resolved crystallography

Lab MattersScience & Technology The recent construction of the new ID29 beamline in Grenoble is pioneering a new way of doing experiments in time-resolved crystallography and opening up technology transfer possibilities

2022

lab-mattersscience-technology

11 October 2022 EMBL scientists sampling at the coastline of Iceland in August 2022

Examining life along Iceland’s coasts

Lab MattersScience & Technology The final pilot project in Iceland marked the countdown to the ‘Traversing European Coastlines’ (TREC) expedition to study coastal ecosystems and their response to changes in the environment.

2022

lab-mattersscience-technology

29 September 2022 young girl in lab coat

Tools for teachers

Lab Matters EMBL reminds teachers of freely available educational resources and workshops just in time for school.

2022

lab-matters

21 September 2022 Photo of the speakers during the panel discussion. Edith Heard is talking. In front of the panel, there is the audience seen from the back, and behind the panel there are banners with the DESY PETAR IV logos and a slide displaying the names of the panellists.

PETRA IV and future opportunities at EMBL Hamburg beamlines

Lab MattersScience & Technology EMBL joined a kick-off event focusing on the developments related to the upgrade of the PETRA III synchrotron storage ring to PETRA IV at the DESY campus, where EMBL Hamburg is located. PETRA IV could open new possibilities at EMBL Hamburg, contributing to the goals of the EMBL Programme…

2022

lab-mattersscience-technology

20 September 2022 8 representatives of both the Dieter Schwarz Foundation and EMBL are standing in the EMBL Imaging Centre foyer facing the camera

Life Science Alliance starts new chapter

ConnectionsLab Matters Dieter Schwarz Foundation renews 3-year funding to EMBL for the EMBL | Stanford Life Science Alliance, a unique international collaboration bringing together researchers from the two leading institutions to develop transformative technologies and accelerate biomedical research.

2022

connectionslab-matters

15 September 2022 The foreground shows two yellow pipes representing the human gastrointestinal tract coming together, representing the confluence of donor and recipient gut ecosystems. Bacteria can be seen as green shapes inside the pipes and various kinds of interactions between them are shown symbolically as a mixing of colours.

When microbiomes collide

Science & Technology EMBL researchers used data from over 300 human faecal microbiota transplants to gain an ecological understanding of what happens when two gut microbiomes clash.

2022

sciencescience-technology

9 September 2022 A female career advisor at computer participates in webinar

Insights into scientific careers

Lab Matters As the career landscape continues to change for PhDs and postdocs, the EMBL Fellows’ Career Service offers webinars that present professional options in and beyond academia.

2022

eventslab-matters

7 September 2022 Female scientist stands in laboratory setting

Augmenting science

Lab Matters The Scientific Visitor Programme shares EMBL tools and talent with outside researchers in collaborative, multidisciplinary environments.

2022

lab-matters

1 September 2022 4D reconstruction of a mouse limb with lateral and top view.

Building the ideal limb

Science & Technology EMBL researchers use a “fearless” computer reconstruction and a two-centuries-old mathematical approach to study limb bud growth.

2022

sciencescience-technology

31 August 2022 A Physarum polycephalum with different colours, where each colour shows the expansion of the cell at various time points.

Spotlight: A giant in action

Science & Technology Physarum polycephalum, a single, giant cell containing tens of thousands of nuclei is large enough to be photographed with a phone.

2022

picture-of-the-weekscience-technology

24 August 2022 A building with glass facades and courtyard in front.

Spotlight: EMBL Imaging Centre, Heidelberg

Lab Matters EMBL’s imaging centre makes advanced microscopy technologies accessible to the international scientific community.

2022

lab-matterspicture-of-the-week

5 August 2022 A rod-like structure with green and magenta segments representing cellular markers.

Making patterns visible

Science & Technology How do gene expression patterns result in the generation of different cell types? Scientists at EMBL Heidelberg used the zebrafish notochord to find out.

2022

sciencescience-technology

4 August 2022 An illustration provides representation of fingers hovering over a cell phone

Zooming in to get the full picture

Science & Technology EMBL and UW researchers plus additional collaborators have constructed a complete map of fruit fly embryonic development using machine learning. This research is foundational to better understanding overall embryo development in other species, including humans.

2022

sciencescience-technology

1 August 2022

Shining a light on how bacteria interact

Science & Technology Machine learning has helped researchers uncover new insights into how bacteria infect host cells.

2022

research-highlightssciencescience-technology

26 July 2022 Group of around 100 people posing in a terrace in front of the sea.

A summer of scientific exchange in Barcelona

ConnectionsLab Matters EMBL’s site by the sea hosted a trio of conferences this summer, covering topics ranging from vascular biology to engineered living systems to evolution.

2022

connectionslab-matters

20 July 2022 A woman stands in front of shelving filled with notebook binders.

Welcome: Maria Papanikolaou

Lab MattersPeople & Perspectives EMBL’s new archive and records manager, Maria Papanikolaou, explains the dual role she and an additional colleague will have in the Office of Science Information Management.

2022

lab-matterspeople-perspectives

18 July 2022 Large, elongated purple molecule has an on/off switch on it pointed to on.

The retron switch

Science & Technology EMBL researchers now understand the function of an elusive small DNA in bacteria and have developed a tool that can be used to better understand what might ‘switch on’ bacterial immune defences.

2022

sciencescience-technology

14 July 2022 Visualising the ocean below and above surface, showing several species and giving written details on the ocean microbiome composition

Priorities for ocean microbiome research

Science & Technology Microbial communities play essential roles in ocean ecology and planetary health. A recent publication highlights priorities for understanding and protecting ocean microbiomes.

2022

sciencescience-technology

13 July 2022 Decorative image showing a double helix DNA road and with what look like road signs.

Uncharted territories in the human genome

Science & Technology Scientists identify previously unexplored gene segments to be added to human genome databases.

2022

research-highlightssciencescience-technology

5 July 2022 A view of the EMBL Imaging Centre with fields in the background

The EMBL Imaging Centre: making it happen

Connections Creating a cutting-edge facility for the global life science community doesn't happen overnight. We spoke to some of those who worked to turn this dream into a reality.

2022

connectionsevents

29 June 2022 Two scientists are surrounded by an illustration of various types of molecules in pastel colours

EMBL 2021 Annual Report published

EMBL AnnouncementsLab Matters EMBL’s 2021 Annual Report is now available, sharing mission highlights from the year in a new digital-first, sustainable format.

2022

embl-announcementslab-matters

22 June 2022 Edith Heard

The world needs science, and science needs women

Lab MattersPeople & Perspectives EMBL Director General Edith Heard joined other L’Oreal-UNESCO Laureates in Paris for a series of events celebrating these outstanding researchers and their contributions.

2022

lab-matterspeople-perspectives

10 June 2022 A colourful structural model of the doughnut-shaped human nuclear pore complex seen from above.

Puzzling out the structure of a molecular giant

Science & Technology Scientists have solved several mysteries around the structure and function of a true molecular giant: the human nuclear pore complex. They created the most complete model of the complex thanks to combining the program AlphaFold2 with cryo-electron tomography, integrative modelling, molecular…

2022

sciencescience-technology

8 June 2022 Two female scientists shown against a green background

2022 EMBL Alumni Awards Winners announced

EMBL Announcements Two former EMBL staff members have been recognised for their outstanding contributions to research in the fields of brain evolution and cancer.

2022

alumniembl-announcements

7 June 2022 Female scientist photographed in a garden

Welcome: Pascale Cossart

Lab MattersPeople & Perspectives Pascale Cossart, one of the world’s foremost authorities on the biology of Listeria, brings four decades of expertise in intracellular bacterial parasitism to EMBL as a visiting scientist.

2022

lab-matterspeople-perspectives

3 June 2022 he internal structure of a mitotic chromosome is shown with colourful threads representing DNA, one of which is shown being packaged into loops by the condensin protein complex. The background shows mitotic chromosomes in the cellular space

Shaping up the genome for cell division

Science & Technology Researchers have discovered the mechanism by which a family of DNA motor proteins packages loosely arranged strands of DNA into compact individual chromosomes during cell division.

2022

sciencescience-technology

2 June 2022 BII and EMBL logos are on a white band set against a wavy green background

Teamed up to innovate

ConnectionsLab Matters A new formal collaboration agreement enables will help smooth the transition from fundamental science to innovation.

2022

connectionslab-matters

1 June 2022

EMBL in Italy event held at GSK Vaccines in Siena

Connections The GSK Vaccines site in Siena hosted the annual EMBL in Italy event. The hybrid meeting brought together industry leaders, representatives from biotech start-ups, data scientists, and researchers from academia.

2022

alumniconnections

21 May 2022 Portrait photo of Edith Heard

Edith Heard elected as a member of The Royal Danish Academy of Sciences and Letters

EMBL AnnouncementsLab Matters EMBL Director General Edith Heard has been elected as a foreign member of The Royal Danish Academy of Sciences and Letters in recognition of her academic excellence. Heard is among 15 new members of the Academy, which has been advancing basic research and interdisciplinarity for nearly 280 years.

2022

embl-announcementslab-matters

18 May 2022 The visiting group from the Business Academy Aarhus during lunch at the EMBL Hamburg’s terrace

EMBL Hamburg is helping train lab techs of the future

Lab Matters Students from the Business Academy Aarhus visit EMBL Hamburg annually. Many of them return later as trainees to gain experience as lab technicians. EMBL Hamburg offers great opportunities to learn diverse techniques and work with various equipment. This experience helps them in their future jobs in…

2022

lab-matters

11 May 2022 Man standing on a balcony

Peter Harrison – Genome Analysis Team Leader

Lab MattersPeople & Perspectives Peter Harrison discusses the importance of data accessibility and his passion for biodiversity and agricultural genomics.

2022

lab-matterspeople-perspectives

10 May 2022

Royal Society honour for Eileen Furlong

EMBL AnnouncementsLab Matters EMBL’s Head of Genome Biology announced as Fellow of the Royal Society for her exceptional contributions to science.

2022

embl-announcementslab-matters

6 May 2022 Drawing of two chromosomes in which a highlighted area is switched around.

Flip-flop genome

Science & Technology Researchers at EMBL Heidelberg found that inversions in the human genome are more common than previously thought, which impacts our understanding of certain genetic diseases.

2022

sciencescience-technology

5 May 2022 Colourful vertical panels each show different microscopic images possible with the high-tech tools in EMBL's Imaging Centre

Enabling imaging across scales

EMBL Announcements EMBL’s first Imaging Centre Symposium will occur onsite at EMBL and include tours of the new Imaging Centre on 31 May, introducing participants to the facility and its staff and featuring talks on the rapid developments in imaging technologies that have led to notable biological and medical…

2022

embl-announcementsevents

5 May 2022 Microscopy image showing mouse cells in blue on a dark background. The mouse cells look like little blue blobs.

Interpreting bioimages with deep learning

Science & Technology Virginie Uhlmann shares her tips for using deep learning for bioimage analysis in the life sciences.

2022

perspectivessciencescience-technology

28 April 2022 Microsocopy image of Pair of somites. Blue is a nuclear marker (DAPI) and red is an apical marker (ZO-1).

Unravelling the origins of the human spine

Science & Technology Scientists at EMBL Barcelona have created for the first time a 3D in vitro model that recapitulates the periodic formation of human somites – structures that give rise to the spinal column.

2022

sciencescience-technology

27 April 2022 Portrait of Kristina Djinović-Carugo

Next Head of EMBL Grenoble appointed

EMBL AnnouncementsLab Matters Professor Kristina Djinović-Carugo has been appointed as the next head of EMBL Grenoble. She will join EMBL in July from the Max Perutz Laboratories at the University of Vienna, where she is currently Head of the Department of Structural and Computational Biology and full Professor of Structural…

2022

embl-announcementslab-matters

27 April 2022 Kristina Djinović-Carugo sitting at her desk.

Meet the next Head of EMBL Grenoble

Lab MattersPeople & Perspectives Slovenian structural biologist Kristina Djinović-Carugo will join EMBL in July as the new Head of EMBL Grenoble. We spoke to her about her background, research interests, and plans for EMBL Grenoble.

2022

lab-matterspeople-perspectives

12 April 2022

EMBL consolidates ties with Sapienza University

ConnectionsLab Matters EMBL and the Sapienza University of Rome confirm their reciprocal interest in intensifying collaborations and launch new opportunities for exchange of expertise

2022

connectionslab-matters

8 April 2022 a metaphor for the process of epigenetic inheritance

A metaphor for epigenetic inheritance

Science & Technology Recent studies from the Hackett group at EMBL Rome have revealed new insights on the mechanism regulating transmission of non-genetic information during embryonic development, and inspired a scientific illustration

2022

sciencescience-technology

6 April 2022 Portrait photo of Matthias Hentze surrounded by a colourful background

Matthias Hentze receives Centenary Award

EMBL AnnouncementsLab Matters EMBL Heidelberg’s Matthias Hentze receives the Biochemical Society’s Centenary Award for his discoveries in RNA biology.

2022

embl-announcementslab-matters

30 March 2022 Man standing in front of a wall with scientific imagery including protein structures

Welcome: John Lees

Lab MattersPeople & Perspectives John Lees joins EMBL-EBI as a Group Leader in Pathogen informatics and modelling.

2022

lab-matterspeople-perspectives

23 March 2022 Two Drosophila embryos stained with fluorescent dye on a purple background that indicates either solid or liquid state

From liquid to solid to drive development

Science & Technology Condensates are membraneless organelles that control specific functions within a cell. Scientists at EMBL Heidelberg have shown how the physical state of condensates can influence biological function.

2022

sciencescience-technology

20 March 2022 Portrait photo of EMBL Group Leader Judith Zaugg against a green background.

Judith Zaugg from EMBL Heidelberg receives ERC Consolidator Grant

EMBL AnnouncementsLab Matters Judith Zaugg, Group Leader at EMBL Heidelberg, has been awarded an ERC Consolidator Grant of €2 million funded under the European Union’s Horizon Europe research and innovation programme. Over the next five years, the grant will enable her group to study cellular interactions in the human bone…

2022

embl-announcementslab-matters

17 March 2022 EMBL statement visual

EMBL’s statement on the invasion of Ukraine

EMBL AnnouncementsLab Matters EMBL condemns in the strongest terms the unjustified military invasion of Ukraine by the Russian Federation, with the support of Belarus, and the resulting loss of life and human suffering. We express our deepest sympathy to the Ukrainian people and to all the victims of this war.  As an…

2022

embl-announcementslab-matters

16 March 2022 Image of a whole lung piece and its internal delicate structure

Putting Cryptococcus in context

Science & Technology EMBL’s imaging technology helps researchers gain insights in the fungus’ journey from the lung to the brain.

2022

sciencescience-technology

4 March 2022 Colourful shapes are set against a black background and white grid, symbolic of aspects of infection biology.

A postdoc conference spotlighted in tweets

Lab Matters EMBL hosted a futuristic infection biology conference, but it offered even more: an opportunity for postdocs to share their work and network towards future research homes.

2022

eventslab-matters

4 March 2022 Science art expressing the concept of transcriptional neighbourhoods regulating transcript isoform lengths and expression levels.

Understanding genomes, piece by piece

Science & Technology Genomes are made up of thousands of individual pieces – genes – which are expressed at different levels. Researchers at EMBL have shed light on how the placement of a gene affects its expression, as well as that of its neighbours.

2022

sciencescience-technology

4 March 2022 A gloved hand holds a slide with visible wells containing Matrigel immersed in culture medium. A magnified close-up shows a mouse embryo developing over the course of 48 hours

A 3D culture model to study embryo growth

Science & Technology A recent study by EMBL researchers proposes a new method to grow early embryos in the laboratory. With a 3D culture set-up, scientists can closely monitor the changes embryos undergo around the time of implantation.

2022

sciencescience-technology

2 March 2022 woman stands in front of computer in workplace

Academia, industry, or somewhere else?

Lab Matters New study: EMBL PhDs and postdocs develop skills that make them highly employable in roles that drive research and innovation in academia, industry, and other sectors.

2022

alumnilab-matters

2 March 2022 Image composition showing a building with sun reflecting off the glass and microscopy images of microorganisms in multiple colours.

‘The World of Molecular Biology’ exhibition

EMBL AnnouncementsLab Matters The new permanent ‘The World of Molecular Biology’ exhibition will open in mid-2023 at EMBL’s headquarters in Heidelberg. It will encourage people to actively engage with science and its relevance for everyday life.

2022

embl-announcementslab-matters

25 February 2022 Three colourful overlapping circles arranged in a row, a fruit-fly embryo being visible within each. Small circles within the embryos represent cell lineages.

Converging lenses on embryo development

Science & Technology Researchers from the Furlong group at EMBL have come up with a way to observe the development of fruit-fly embryos simultaneously at the genetic and cellular levels, generating a high-resolution and integrated view of how different cell lineages form.

2022

sciencescience-technology

23 February 2022 A photo of the campus of the Aarhus University buildings and green lawn.

Molecular medicine across borders

ConnectionsLab Matters The 11th annual Nordic EMBL Partnership for Molecular Medicine meeting was hosted in virtual format by DANDRITE, the Danish node of the Partnership, from 31 January–2 February 2022. The programme included updates from all partnership nodes, discussions about opportunities for new collaborations,…

2022

connectionslab-matters

23 February 2022 A male scientist in a white shirt stands at a walkway railing.

Welcome: Michael Dorrity

Lab MattersPeople & Perspectives Michael Dorrity, one of EMBL’s newest group leaders, is studying how the environment influences early life stages in zebrafish.

2022

lab-matterspeople-perspectives

10 February 2022 Pfizer logo with pipette tips in the background

Pfizer joins the Open Targets consortium

Connections Open Targets, a consortium focused on drug target identification, prioritisation, and validation, announced today that Pfizer has joined as a partner.

2022

announcementsconnectionsscience

9 February 2022 The logos of EMBL and the Latvian Biomedical Research and Study Centre

EMBL and Latvia deepen collaboration

Connections Agreement signed with Latvia’s Biomedical Research and Study Centre will boost academic exchange and collaboration on some of the largest challenges facing human and planetary health.

2022

connectionsevents

1 February 2022 A photograph of the Amazonian lancehead snake Bothrops atrox

Decoding the secrets of snake venom

Science & Technology EMBL Hamburg’s Grzegorz Chojnowski from the Wilmanns Group developed software called findMySequence, which identifies proteins’ amino-acid sequences based on electron cryo-microscopy and X-ray crystallography data. It’s useful for identifying unknown proteins in samples from natural sources.

2022

sciencescience-technology

27 January 2022 A headshot of Mark Daly with dark background behind him.

Fostering excellence, diversity, and mobility in the Nordic EMBL Partnership

ConnectionsLab Matters Ahead of the annual meeting of the Nordic EMBL Partnership for Molecular Medicine, we spoke with its new Speaker, Mark Daly. Mark Daly, FIMM Director, recently accepted the post of Speaker of the Nordic EMBL Partnership. He explains his vision of the future cooperation between EMBL and the Nordics.

2022

connectionseventslab-matters

24 January 2022 Three women are seen in front of a computer, with the electron micrograph of a woodlouse visible on the screens

EMBL Imaging Centre kickstarts training with workshop for undergraduates

Lab Matters The new EMBL Imaging Centre held its first on-site training workshop, introducing undergraduate students to the basics of volume electron microscopy. This marks the first of many opportunities to aid capacity-building in imaging techniques in Europe.

2022

lab-matters

21 January 2022 The cross-section of a cell expressing a green fluorescently tagged protein and illuminated by a blue laser is visible in the foreground, surrounded by a vortex of cells

Cell sorting enters a new dimension

Science & Technology EMBL researchers, in collaboration with BD Biosciences, have demonstrated a new technology that allows rapid image-based sorting of cells. The new technology represents a major upgrade to flow cytometry and has applications in diverse life science fields.

2022

sciencescience-technology

19 January 2022 "From Molecules to Ecosystems" are words on top of a collage of images that span from molecules to ecosystems

A new era for European molecular biology

EMBL AnnouncementsLab Matters EMBL announces details about its next programme, ‘Molecules to Ecosystems’. It will guide studying life across scales and in context with changing environments.

2022

announcementsembl-announcementslab-matters

18 January 2022 Science illustration composed by a photographic film highlighting three-dimensional structures of a protein complex involved in splicing.

Capturing ‘snapshots’ of a crucial step in RNA splicing

Science & Technology The Galej group at EMBL Grenoble has recently obtained high resolution snapshots of a crucial step in RNA splicing involving the U2 snRNP complex, a crucial component of the human spliceosome.

2022

sciencescience-technology

14 January 2022 Woman standing next to a hedge

Welcome: Melissa Harrison

Lab MattersPeople & Perspectives Melissa Harrison joins EMBL-EBI as the new Team Leader of Literature Services. We found out more about her plans for open access publishing and Europe PMC.

2022

lab-matterspeople-perspectives

3 January 2022 Mixture of life science symbols inside a circle set against background of green and blue

The start of a journey

Lab MattersPeople & Perspectives This year marks the beginning of EMBL’s next programme ‘Molecules to Ecosystems’ to advance the understanding of life across scales and in the context of changing environments.

2022

lab-matterspeople-perspectives

22 December 2021 Scientific illustrations of MEG3, a very large RNA involved in cell proliferation. IAB and EMBL logos are located in the center of the illustration.

EMBL-IAB collaboration on the rise

ConnectionsLab Matters The memorandum of understanding (MoU) signed between EMBL and the Institute for Advanced Biosciences (IAB) a year ago has already catalysed new grants for joint research projects related to cancer and infection biology, thereby deepening collaborative activities.

2021

connectionslab-matters

21 December 2021 A model of the doughnut-shaped nuclear pore complex. Individual molecules are marked in various colours.

Observing the secret life of molecules inside the cell

Science & Technology EMBL Hamburg’s Kosinski Group, the Beck Laboratory at the Max Planck Institute of Biophysics, and colleagues at EMBL Heidelberg recorded the nuclear pore complex contracting in living cells. They visualised the movement with an unprecedented level of detail with help of new software called…

2021

sciencescience-technology

20 December 2021 Concentric circles and lines in different colours, representing fingerprints. Text: "Equality, Diversity, and Inclusion Strategy."

Fostering diversity and equality

Lab Matters Showing a continued commitment to providing a diverse and inclusive organisation for conducting leading molecular biology research, EMBL has launched an Equality, Diversity, and Inclusion (EDI) strategy.

2021

lab-matters

20 December 2021 A detailed structure map shows two proteins interacting in the foreground, each shown in a different colour. The background shows small green dots marking bacteria

Solving molecular puzzles to find the perfect fit

Science & Technology Using cryo-EM and structural biology techniques, EMBL researchers have shown how two proteins of Legionella pneumophila interact. This finding sheds light on a mechanism critical to the infection process and could lead to the development of new drugs to treat pneumonia.

2021

sciencescience-technology

15 December 2021 An outline of Earth, covered with depictions of bacteria. The image of Earth is within a the frame of a computer window. There is an “Upload file” button on the bottom left, and a mouse cursor on the right.

Connecting the dots between bacterial genes around the world

Science & Technology Bork Group at EMBL Heidelberg analysed a new global gene database to study how genes emerge and spread across various habitats on our planet. In the future, the group will expand the database and use it for studying microbial gene evolution and dispersal at a finer-grained scale.

2021

sciencescience-technology

9 December 2021 Colourful interwoven coils are displayed against a grid of small black and white photographic images.

A gallery of human RNA polymerases

Science & Technology New structural biology research provides fundamental information critical to understanding enzyme mutations connected to rare diseases and cancers.

2021

sciencescience-technology

9 December 2021 Portrait photo of Eileen Furlong against blue-green background.

Eileen Furlong honoured with Leibniz Prize

EMBL AnnouncementsLab Matters EMBL Senior Scientist and Head of the Genome Biology Unit is among the researchers honoured for outstanding work by the German Research Foundation (Deutsche Forschungsgemeinschaft, DFG).

2021

embl-announcementslab-matters

9 December 2021 Logos of CNRS and EMBL with text “memorandum of understanding”

Strengthening collaborations in France

ConnectionsLab Matters EMBL and the French National Centre for Scientific Research (CNRS) signed a memorandum of understanding.

2021

connectionslab-matters

8 December 2021 An illustration of the human gut, with coloured shapes representing bacteria. Three different drugs and drug combinations are shown affecting the bacteria, represented by changes in colour

The impact of drugs on gut microbes is greater than we thought

Science & Technology Researchers studying a massive cohort of European patients have found that commonly prescribed drugs for cardiometabolic disorders can have long-term effects on the gut microbiome. Such effects can complicate the understanding of how disease affects the microbiome and must be taken into…

2021

sciencescience-technology

7 December 2021 A cartoon image showing a person's arm and a needle with a vaccine being injected into it. The text on the left reads: "EMBL research: How structural biologists at EMBL Hamburg help to develop and improve RNA vaccines"

How structural biology helps to make RNA vaccines

Science & Technology RNA vaccines, such as the ones for COVID-19, represent a new approach in vaccine technology. Cy Jeffries, faculty staff scientist at EMBL Hamburg, explains the clever technology behind RNA vaccines, and how structural biology contributes to its development. EMBL Hamburg collaborated on several…

2021

sciencescience-technology

29 November 2021 Male scientist in front of blurred woodland background

Welcome: Niccolò Banterle

Lab MattersPeople & Perspectives Using gene editing and three types of microscopy, one of EMBL’s newest group leaders is deciphering the functions of one of the smallest molecules involved in cell division, motility, and signalling, known as a centriole.

2021

lab-matterspeople-perspectives

25 November 2021 Female scientist in front of a background of green plants

Welcome: Maria Zimmermann-Kogadeeva

Lab MattersPeople & Perspectives Maria Zimmermann-Kogadeeva is one of EMBL’s newest group leaders and a computational biologist whose research group applies computational modelling to better understand the metabolism of gut bacteria and their potential to have far-reaching impacts on other organs.

2021

lab-matterspeople-perspectives

24 November 2021 A man standing in front of hedges

Welcome: Tudor Groza

Lab MattersPeople & Perspectives Tudor Groza joins EMBL-EBI as our new Phenomics Team Lead. We found out from Tudor exactly what this new role will entail

2021

lab-matterspeople-perspectives

16 November 2021 Collage showing different species that play an essential part in global food security, including cattle, pollinators and plants

Can data help feed a hungry world?

Science & Technology How genomics, open data, and multidisciplinary science can improve food security.

2021

sciencescience-technology

15 November 2021 3D visualization of the vascularized placenta barrier model on-a-chip.

Building a 3D placenta on a chip

Lab MattersScience & Technology A new model could serve as a platform to investigate critical placenta barrier phenomena, including defence against bacteria, viruses, and parasites.

2021

lab-mattersscience-technology

13 November 2021 close-up of 3 birds

EMBL alum takes DNA sequencing to the field

Science & Technology EMBL alum Lara Urban has developed mobile DNA approaches to monitor impacts upon biodiversity in remote areas of New Zealand and elsewhere.

2021

alumniscience-technology

12 November 2021 Pia Lavriha and Anna Steyer look at cryo-electron microscopic images on a computer screen.

EMBL Imaging Centre welcomes first external user

Lab MattersScience & Technology Correlative microscopy service enables PhD student from Switzerland to study structure and location of proteins cells use to communicate.

2021

lab-mattersscience-technology

10 November 2021 Logo showing an opened padlock and the words “Data Use Ontology” and biomedical samples in background.

DUO: streamlining access to biomedical datasets

Science & Technology The GA4GH Data Use Ontology (DUO) supports a data authorisation and access framework to streamline consent to use biomedical data

2021

sciencescience-technology

10 November 2021 Graphic representations of different types of bacteria.

Making sense of bacterial DNA data

Science & Technology A vast, curated collection of bacterial genomes is now organised, searchable and open to the community.

2021

sciencescience-technology

9 November 2021 students looking a computer monitor and microscope

New horizons for the EIPP

Lab Matters EMBL's PhD and postdoc programmes evolve to the more multidisciplinary way of doing great molecular biology research.

2021

lab-matters

8 November 2021 A scientist is carefully handling capilars at the P12 beamline at EMBL Hamburg.

EMBL Hamburg trains future generations of life scientists in using SAXS

Lab MattersScience & Technology Each year, EMBL Hamburg’s Svergun Group offers practical EMBO courses and lecture courses on biological small-angle X-ray scattering (SAXS). The courses provide young scientists an opportunity to gain hands-on experience by measuring their own samples, and by exploring different aspects of SAXS…

2021

lab-mattersscience-technology

5 November 2021 A headshot photo of Ken Holmes from July 2021

Ken Holmes

People & Perspectives Ken Holmes, outstanding pioneer of structural biology and founder of EMBL´s Hamburg site, died on 2 November 2021 at the age of 87.

2021

alumnipeople-perspectives

5 November 2021 Three-dimensional rendering of sponge neuroid cells (coloured orange) and sponge digestive cells (coloured green).

More than a gut reaction

Science & Technology What can sponges tell us about the evolution of the brain? Sponges have the genes involved in neuronal function in higher animals. But if sponges don’t have brains, what is the role of these? EMBL scientists imaged the sponge digestive chamber to find out.

2021

sciencescience-technology

28 October 2021 female scientist sits in front of building

Welcome: Svetlana Dodonova

Lab MattersPeople & Perspectives Svetlana Dodonova is one of EMBL's newest group leaders, leading a team of researchers who will study how genetic material is organised inside cells using structural biology approaches.

2021

lab-matterspeople-perspectives

26 October 2021

Science for sustainability

ConnectionsLab Matters The engagement of US and European Big Science facilities

2021

connectionslab-matters

26 October 2021 Photo of researcher using MGnify database

Novel enzymes for a Green Economy

Science & Technology Using metagenomic data to find novel enzymes for plastic degradation and beyond

2021

sciencescience-technology

25 October 2021 A collage of the visuals representing each of the three modules of the eSPC platform.

Biophysics analysis made easy with an online tool

Science & Technology EMBL Hamburg’s Sample Preparation and Characterisation (SPC) Facility has released eSPC, an online platform for analysing data from biophysical experiments. The platform enables the scientific community to analyse data from different experiments without the need to travel.

2021

sciencescience-technology

22 October 2021 Oblong shape with two holes and coloured dots inside, representing phytoplankton cells and nitrogen-fixing bacteria

Analysis and sorting with flow cytometry

Lab MattersScience & Technology A technology around since the ‘60s, flow cytometry has increasing applications. New leadership at EMBL’s flow cytometry facilities is looking to ease use, expand training, and encourage more collaboration.

2021

lab-mattersscience-technology

15 October 2021 In the middle, there are two molecules of pUL21. One is blurred, to represent the molecule’s flexibility. In the background are two neuronal scenes. The one on the left is healthy and has a smooth surface. The one on the right is infected, which is represented by several green viral particles.

How herpes seizes proteins’ means of production

Science & Technology The Graham and Crump groups at the University of Cambridge and the Svergun Group at EMBL Hamburg have discovered a mechanism by which the herpes simplex virus takes control of the molecular machinery of human cells. Their work reveals how a dedicated viral protein hijacks key host proteins, forcing…

2021

sciencescience-technology

13 October 2021 Illustration of a community of bacteria. Pills represent an antibiotic that can be used to treat an infection, and a second drug that could protect many gut bacteria from antibiotics.

Tackling the collateral damage from antibiotics

Science & Technology Researchers from EMBL’s Typas group and collaborators have analysed the effects of 144 antibiotics on the wellbeing of gut microbes. The study improves our understanding of antibiotics’ side effects and suggests a new approach to mitigating the adverse effects of antibiotics therapy on gut…

2021

sciencescience-technology

12 October 2021 Man in white and blue t-shirt in outdoor setting

When ‘good’ cells go ‘bad’

Science & Technology If researchers can identify specifically when good cells go bad, they can potentially understand disease better.

2021

sciencescience-technology

8 October 2021 Logos of Ifremer and EMBL with text: “memorandum of understanding”. Illustrations of marine animals and numbers in the background.

EMBL and Ifremer cooperate to advance ocean sciences

ConnectionsLab Matters The two organisations have signed a memorandum of understanding to support scientific cooperation in the exploration of coastal and oceanic ecosystems.

2021

connectionslab-matters

7 October 2021 students looking a computer monitor and microscope

EMBL welcomes young scientists

Lab Matters This autumn, students begin their PhD in research groups across EMBL’s six sites.

2021

lab-matters

7 October 2021 SARS-CoV-2 and planet Earth are merged together in this illustration

Six Ways to Protect the Planet Against Pandemics*

Science & Technology EMBL will host a conference to look at the state of the pandemic, lessons learned, and ways to improve pandemic preparedness. Here’s a sneak peek into what promises to be another interesting and informative EMBL conference.

2021

eventsscience-technology

5 October 2021 Illustration of a globe with colourful shapes and symbols superimposed.

A cellular atlas of an entire worm

Science & Technology EMBL scientists and colleagues have developed an interactive atlas of the entire marine worm Platynereis dumerilii in its larval stage. The PlatyBrowser resource combines high-resolution gene expression data with volume electron microscopy images.

2021

sciencescience-technology

4 October 2021 Logos of University of Tartu and EMBL with text: “memorandum of understanding”. Illustrations of microorganisms in the background.

EMBL strengthens links with Estonia

ConnectionsLab Matters A memorandum of understanding (MoU) has been signed between EMBL and the University of Tartu, a leading centre of research and training. The MoU aims to strengthen cooperation between EMBL and the life science research community in Estonia.

2021

connectionslab-matters

30 September 2021

New microscopy technique makes deep in vivo brain imaging possible

Science & Technology Scientists in EMBL’s Prevedel Group have developed a pioneering microscopy technique that allows researchers to observe cells hidden within opaque tissues, such as live neurons embedded deep in the brain.

2021

sciencescience-technology

29 September 2021 Female scientist working at a biosafety cabinet, wearing a yellow protective gown and black gloves.

Transferable skills

Lab MattersPeople & Perspectives In the lab, Diënty Hazenbrink works with microbes that live in our guts. In her free time, she enjoys wildlife photography. A shared set of skills facilitates both activities.

2021

lab-matterspeople-perspectives

23 September 2021 Pink and blue dominate a blurry image against a black background that is actually a global image of a 30-day-old Octopus vulgaris

The secret life of baby octopuses

Science & Technology Some of the most amazing creatures live in the deep blue sea. The Mesoscopic Imaging Facility (MIF) at EMBL Barcelona was recently involved in studying one unique feature of the octopus: the ephemeral structures on the surface of their skin called Kölliker’s organs.

2021

sciencescience-technology

22 September 2021 Logos of EMBL and Helmholtz Association on white background, over a green-and-blue pattern in the background.

EMBL and Helmholtz Health join forces

ConnectionsLab Matters EMBL and Helmholtz Association have signed a memorandum of understanding. The expanded collaboration of both institutions will focus on research related to health.

2021

connectionslab-matters

17 September 2021 Artistic representation of the complex cell circuit forming the retina

Vision unveiled: new roles for the retina in visual processing

Science & Technology EMBL scientists have found evidence of an unexpected role for retinal cells in pre-processing visual information; their results provide potential opportunity for future prosthetic visual aids.

2021

research-highlightssciencescience-technology

15 September 2021 A dark blue classic star map view is overlaid upon scientific data

Charting a multi-omic universe

Science & Technology A research collaboration used machine learning to map tumour molecular make-up, potentially paving way to more customised cancer treatment.

2021

sciencescience-technology

9 September 2021 Portrait of former EMBL Director General Iain Mattaj

German Cross of Merit for former EMBL Director General

EMBL Announcements Former EMBL Director General Professor Iain Mattaj was awarded the German Cross of Merit (‘Verdienstkreuz 1. Klasse des Verdienstordens der Bundesrepublik Deutschland’) at a ceremony held at EMBL Heidelberg on 9 September 2021.

2021

alumniembl-announcements

9 September 2021 A student in front of a computer watches a scientist working in a laboratory

New horizons for virtual learning

Lab Matters EMBL's science education department makes the latest scientific research more accessible for teachers and students.

2021

eventslab-matters

8 September 2021 Illustration of two halves of a pill, which releases chemical molecules that are taken up by gut bacteria in the vicinity.

Common medications accumulate in gut bacteria

Science & Technology A new collaborative study led by EMBL group leaders Kiran Patil, Nassos Typas, and Peer Bork has found that common medications accumulate in human gut bacteria. This process reduces drug effectiveness and affects the metabolism of common gut microbes, thereby altering the gut microbiome.

2021

sciencescience-technology

7 September 2021 Close up of the interior of a light-sheet microscope, featuring optical equipment and a transparent cube.

A flip book for biological systems

Science & Technology In the Mesoscopic Imaging Facility (MIF) at EMBL Barcelona, researchers study the details of biological systems in the context of organs, body parts, or entire organisms. This image shows OPTiSPIM1, one of the custom light-sheet microscope setups available at the facility.

2021

sciencescience-technology

6 September 2021 Cells organised according to their transcript data changing to the seqFISH mouse embryo map.

The Spatial Mouse Atlas: new insights into cell fate

Science & Technology Researchers have combined spatial gene expression information with single-cell genomics data to create a high-resolution atlas of mouse organogenesis.

2021

sciencescience-technology

20 August 2021 Liz Duke in front of the PETRA III synchrotron.

Welcome: Liz Duke

Lab MattersPeople & Perspectives The new team leader at EMBL Hamburg talks about her plans to establish biological X-ray imaging and high-throughput tomography.

2021

lab-matterspeople-perspectives

12 August 2021 Edith Heard's photo portrait in a circle in the middle of the image.

Edith Heard elected to the German National Academy of Sciences Leopoldina

EMBL AnnouncementsLab Matters EMBL Director General Edith Heard has been elected a member of the German National Academy of Sciences Leopoldina. Her admission to the ‘Human Genetics and Molecular Medicine’ section recognises her outstanding professional contributions to science.

2021

embl-announcementslab-matters

10 August 2021 Scientist working on an instrument of the MASSIF-1 beamline

MASSIF-1 beamline in Grenoble supports COVID-19 drug discovery

Lab MattersScience & Technology MASSIF-1, run jointly by EMBL Grenoble and the ESRF, is a beamline for macromolecular crystallography. It is used by the research community to study the 3D structure of proteins, which is important for drug development.

2021

lab-mattersscience-technology

4 August 2021 Head shot of male scientist

Supporting EMBL and fundamental research

People & Perspectives EMBL alumnus Angus Lamond reflects on the process of translating the importance of fundamental research – to EMBL and wider society.

2021

alumnipeople-perspectives

3 August 2021 illustration of health care providers around a big heart

All heart

Science & Technology A community of scientists is looking at the estimated three billion heart muscle cells in a human heart to better understand heart disease.

2021

alumniscience-technology

29 July 2021 Oblong shape with two holes and coloured dots inside, representing phytoplankton cells and nitrogen-fixing bacteria

What lies beneath: the building blocks of life

Science & Technology Analysis of more than 2 million images has boosted understanding of ocean microbes, shedding light on the distribution of nitrogen-fixers at a global level

2021

sciencescience-technology

20 July 2021 Dark grey bird sitting on a metal lamp post. Grass and rock in the background.

A black redstart visits

Lab Matters Mehdi Khadraoui, a former member of the EMBL Communications team, took this close-up of a black redstart.

2021

lab-matters

13 July 2021 From right to left, Ilaria Piazza and Ken Holmes’ portraits are side by side in circles on a greenish background

EMBL Alumni Awards 2021

People & Perspectives EMBL alumni Ilaria Piazza and Ken Holmes have been recognised for their outstanding contributions, and will receive their awards as part of the celebrations for EMBL World Alumni Day.

2021

alumnipeople-perspectives

12 July 2021 Close-up illustration of the Kinesin-1 protein, intertwined with the aTm1 protein in a helix, next to loopy mRNA molecules.

A model of cooperation for transporting mRNA

Science & Technology EMBL scientists generate a high-resolution crystal structure of the Kinesin-1/aTm1 transport complex in the fruit fly.

2021

sciencescience-technology

9 July 2021 Melissa Graewert stands in front of steely machine

From antibodies to nanoplastics

Science & Technology EMBL’s Melissa Graewert and colleagues are taking a structural biologist’s approach to better understanding nanoplastic particles.

2021

sciencescience-technology

8 July 2021 Two men stand outside in front of a building, holding a document and looking at it.

A hidden medal

People & Perspectives We all like a story about rediscovering treasures, right? Well, that’s just what happened recently at EMBL Grenoble!

2021

alumnipeople-perspectives

5 July 2021

Welcome: Sarah Dyer

Lab MattersPeople & Perspectives EMBL welcomes Sarah Dyer, the new Non-Vertebrate Genomics Team Leader at EMBL-EBI.

2021

lab-matterspeople-perspectives

2 July 2021 Portrait photo of a man in front of trees on a balcony

New head for EMBL’s Developmental Biology Unit

EMBL AnnouncementsLab Matters Dr Alexander Aulehla has been appointed the new Head of EMBL’s Developmental Biology Unit, and will take up the role starting in July 2021.

2021

embl-announcementslab-matters

23 June 2021 Bright blue oblong shape with white hairs on surface on black background.

Starlet sea anemone

Science & Technology EMBL PhD student Anniek Stokkermans captured this side view of a Nematostella vectensis larva during this transition, using instrumentation in the Advanced Light Microscopy Facility at EMBL Heidelberg.

2021

picture-of-the-weekscience-technology

22 June 2021 Woman stands at brown railing in front of trees

Welcome: Anna Erzberger

Lab MattersPeople & Perspectives Anna Erzberger, one of EMBL’s newest group leaders, will provide unique perspective as a theoretical biological physicist.

2021

lab-matterspeople-perspectives

17 June 2021 Three researchers surround microscopy equipment in a dark room with red lighting.

Illuminating protein complexes in cells

Lab MattersPeople & Perspectives EMBL group leaders Julia Mahamid, Anna Kreshuk & Jonas Ries awarded Chan Zuckerberg Initiative grant to advance what we see inside cells.

2021

lab-matterspeople-perspectives

16 June 2021 Microscopy images of bacteria against a backdrop of a crowd of humans.

How our gut microbiome changes over time

Science & Technology Researchers investigate how external factors can influence the persistence of microbe species in the human gut

2021

sciencescience-technology

15 June 2021 Small star-like objects are scattered throughout a black background

Twinkle, twinkle, little nuclear pore complex

Science & Technology As perfect as a summer night sky, these nuclear pores help calibrate a customised super-resolution microscope in EMBL’s Ries group.

2021

picture-of-the-weekscience-technology

9 June 2021 R2DT software for RNA structures

Visualising RNA structures using R2DT

Science & Technology New software enables scientists to visualise RNA secondary structures using the world’s largest RNA structure dataset.

2021

sciencescience-technology

8 June 2021 Two scientists in lab coats working on an instrument in the lab.

EMBL external research community survey

Lab Matters EMBL is conducting an Impact Assessment of our experimental services to understand the value these services have for our external user community. If you have accessed EMBL experimental services at one or more of our facilities to support the conduct of your research, we would like to hear from you.

2021

lab-matters

8 June 2021 Purple, blue and yellow dots on a black background.

Dream team

Science & Technology At EMBL, we have many dream teams – groups of individuals who support each other, innovate, and work together. One of those dream teams bridges two core facilities at EMBL Rome.

2021

picture-of-the-weekscience-technology

4 June 2021 Man in white shirt and blue jeans standing on a terrace in front of trees, facing the camera.

The power of community

Lab MattersPeople & Perspectives EMBL Director Matthias Hentze describes the Environmental Research Initiative: a community effort to solve global environmental challenges.

2021

lab-matterspeople-perspectives

3 June 2021 Illustration of a rocky coastline with sailing boat, mountains, underwater organisms, bridge and factory in the background.

Living laboratories

Science & Technology Under the innovative Planetary Biology research theme, EMBL scientists aim to understand life in the context of its environment.

2021

sciencescience-technology

1 June 2021 Two purple and white spheres against dark background.

Nuclear twins

Science & Technology Captured by EMBL postdoc Arina Rybina, these ‘nuclear twins’ are two daughter nuclei straight after division of a HeLa cell.

2021

picture-of-the-weekscience-technology

31 May 2021 Collage showing injection needle, coronavirus and vaccine vials

Genomic surveillance of SARS-CoV-2 in England

Science & Technology The largest in-depth analysis of genomic surveillance data mapping out the dynamics of 62 lineages of the SARS-CoV-2 virus.

2021

sciencescience-technology

25 May 2021 Microscope image of an engineered human blood vessel, featuring individual cells outlined in pink with blue nuclei.

Barriers against malaria

Science & Technology The Bernabeu Group aims to increase our knowledge of cerebral malaria, using in vitro engineered networks of human blood vessels and brain cells.

2021

picture-of-the-weekscience-technology

21 May 2021 Image of a mosquito on a clear surface

EMBL scientists support malaria research

Science & Technology EMBL scientists support research on malaria by providing freely available data resources and using innovative experimental approaches. Our Course and Conference Office facilitates the exchange of knowledge in the field by hosting the annual BioMalPar conference.

2021

sciencescience-technology

20 May 2021 Male scientist in white coat is laboratory setting

Michael Zimmermann receives FEBS Anniversary Prize

EMBL AnnouncementsLab Matters The Gesellschaft für Biochemie und Molekularbiologie has awarded a FEBS Anniversary Prize to Michael Zimmermann for his gut microbiome research.

2021

embl-announcementslab-matters

18 May 2021 Three bright red orange objects in shapes approximating circles with some protrusions are set against a black background.

Cellular fireball or immune cells?

Science & Technology The EMBL Picture of the Week features a series of Jurkat T cells during different stages of the activation process.

2021

picture-of-the-weekscience-technology

17 May 2021 A selection of screenshots featuring participants at the Emerging Infectious Disease conference.

How can we prepare for future pandemics?

Connections Leading international experts gathered to showcase progress in the fight against COVID-19 and share lessons for the future.

2021

connectionsevents

10 May 2021 The image shows Inserm and EMBL logos and illustrates the memorandum of understanding signed between both institutions.

EMBL and Inserm to join forces

ConnectionsLab Matters A memorandum of understanding has been signed between EMBL and Inserm to strengthen their scientific cooperation.

2021

connectionslab-matters

5 May 2021 Woman sits at desk in office setting

After the lecture: Zehra Sayers

People & Perspectives Zehra Sayers explains what makes the SESAME synchrotron special, why we should not fear failure, and why curiosity is her biggest driver.

2021

alumnipeople-perspectives

28 April 2021 Artistic representation of brain and DNA

Uniting strengths to expand research

ConnectionsLab Matters The European Molecular Biology Laboratory and the Italian Institute of Technology have signed an agreement to expand the scope of their collaboration to include areas of mutual interest and in the context of EMBL’s 2022-2026 Programme “Molecules to Ecosystems”.

2021

connectionslab-matters

27 April 2021 Three irregular shapes, made up of green, blue, red and pink speckles, are set against a black background.

SARS-CoV-2 curtails immune response in the gut

Science & Technology EMBL scientists, together with collaborators from Heidelberg University, have provided further evidence of the gut’s role in COVID-19.

2021

sciencescience-technology

27 April 2021 Microscope image of liver cells, highlighted in various colours.

Painting liver cells

Science & Technology A page from a biologist’s colouring book? EMBL’s new interior wall design? Not quite – a bunch of liver cells, grown in the lab so that scientists can learn about fatty liver disease, or steatosis.

2021

picture-of-the-weekscience-technology

26 April 2021 Portrait photo of Edith Heard, EMBL Director General

EMBL DG joins WHO Science Council

ConnectionsLab Matters Edith Heard has been appointed to a new World Health Organization advisory council.

2021

connectionslab-matters

20 April 2021 Black-and-white sphere with coronavirus spike protein structures and a two-layered ring of virus membrane superimposed.

Variations on a spike

Science & Technology What does coronavirus’s spike protein look like in 3D? EMBL scientists and colleagues used cryo-electron tomography and molecular dynamics simulations to find out.

2021

picture-of-the-weekscience-technology

13 April 2021 Picture showing MD3, the micro-diffractometer developed by the Instrumentation team, installed at one of the EMBL Hamburg's beamline. Credits: Kinga Lubowiecka/EMBL

Structural biology at EMBL: driving technology development

Lab MattersScience & Technology Florent Cipriani, who recently retired as Head of the Instrumentation Team after a long career at EMBL Grenoble, is one of the pioneers of instrumentation development in this field.

2021

lab-mattersscience-technology

13 April 2021 EMBL Heidelberg's main building, the top of the façade lit up by sunlight.

Morning sun

Lab Matters Throwback to June 2014: While EMBL Heidelberg’s main entrance is still in the dark, the well-known EMBL logo is already lit by the morning sun.

2021

lab-matterspicture-of-the-week

8 April 2021 Genetics of ageing

Linking genetics and age-related diseases

Science & Technology Researchers have used human medical and genetic data from UK Biobank to investigate the genetics of age-related diseases

2021

sciencescience-technology

7 April 2021 Man standing next to painting

Welcome: Matthew Hartley

Lab MattersPeople & Perspectives The challenges and opportunities when setting up a global archive for bioimages

2021

lab-matterspeople-perspectives

6 April 2021 A model of Glycine Transporter 1, which is located in the cell membrane. In its lower-middle part, it is bound by its inhibitor, which is a much smaller molecule. At its top, Glycine Transporter 1 is bound by a synthetic mini-antibody, called a sybody.

New perspectives for treating psychiatric disorders

Science & Technology Scientists have determined the structure of Glycine Transporter 1. The finding could open new avenues for developing therapeutics for psychiatric disorders

2021

sciencescience-technology

6 April 2021 Sea anemone polyp seen through a microscope, cell nuclei and muscles highlighted.

A multifunctional mouth

Science & Technology This image of a young Nematostella vectensis polyp shows two of the characteristic tentacles as well as the gaping mouth of the animal.

2021

picture-of-the-weekscience-technology

30 March 2021 Ana Boskovic sitting in her office

Welcome: Ana Boskovic

Lab MattersPeople & Perspectives The new group leader at EMBL Rome will study how embryos can inherit non-genetic information from their parents that causes stable and heritable effects

2021

lab-matterspeople-perspectives

30 March 2021 A close-up photo of a shiny droplet of liquid that has been placed into one of the wells of a crystallisation plate.

Droplet beauty

Science & Technology Scientists at EMBL Hamburg use droplets of protein solution to grow protein crystals. By exposing the crystals to X-rays, they are able to determine the protein’s molecular structure.

2021

picture-of-the-weekscience-technology

23 March 2021 Man pouring water in a glass bottle to make coffee.

Green coffee at EMBL

Lab Matters The cafeteria at EMBL Heidelberg now offers espresso and cappuccino with a more intense flavour and which are produced in a ‘green’ way.

2021

lab-matterspicture-of-the-week

16 March 2021 Pink blooming tree in front of functional building.

Italian Spring

Lab Matters EMBL’s site in Monterotondo has recently been blessed with blue skies and sunshine, leading to trees blooming early on campus.

2021

lab-matterspicture-of-the-week

11 March 2021 Man in black t-shirt and jeans wearing glasses sits in front of two computer screens.

From mRNA researcher to BioNTech manager

People & Perspectives EMBL alumnus Pawel Masiewicz has transferred skills and experience gained at EMBL to oversee starting materials for mRNA vaccine development.

2021

alumnipeople-perspectives

9 March 2021 Wolfgang Huber faces the camera smiling

Wolfgang Huber becomes ISCB Fellow

EMBL AnnouncementsLab Matters The contribution of EMBL Group Leader and Senior Scientist Wolfgang Huber has been recognised by the International Society for Computational Biology

2021

embl-announcementslab-matters

9 March 2021 This photo shows the European Photon and Neutron (EPN) science campus on the peninsula at the confluence of the Isère and Drac rivers, where EMBL Grenoble is located.

Touch of springtime in Grenoble

Lab Matters This photo shows the European Photon and Neutron (EPN) science campus where EMBL Grenoble is located. A delightful spring breeze in the air melts the last remaining patches of snow in the mountains.

2021

lab-matterspicture-of-the-week

8 March 2021 Head shot of female social scientist with blond curly hair and blue/grey eyes.

After the lecture: Tracey Brown

Lab Matters Tracey Brown from Sense about Science shares her thoughts on the need to empower women to share and access scientific information.

2021

lab-matters

8 March 2021 Two femail scientists facing each other in discussion.

EMBL prepares women postdocs for leadership

Lab Matters Members of EMBL’s Equality, Diversity and Inclusion Committee explain how EMBL is choosing to challenge through its LEAP mentoring programme.

2021

lab-matters

4 March 2021

Induced pluripotent stem cells reveal causes of disease

Science & Technology Scientists in the Stegle group and colleagues have studied induced pluripotent stem cells from around 1,000 donors to identify correlations between individual genetic variants and altered gene expression. They linked more than 4,000 of the genetic variants responsible for altered expression…

2021

sciencescience-technology

2 March 2021 Microscopy image of stem cells in bone marrow

New avenues for eradicating cancer

Science & Technology A new method has the potential to boost international research efforts to find drugs that eradicate cancer at its source.

2021

sciencescience-technology

2 March 2021

Sleeping beauty

Science & Technology Like caterpillars turning into beautiful butterflies, fruit fly larvae have to go through metamorphosis to finish their development. However, despite the fruit fly Drosophila melanogaster being one of the best studied model organisms in biology, comparatively little attention has been given to this…

2021

picture-of-the-weekscience-technology

26 February 2021 Woman with long brown hair stands in front of snow scene with arms crossed in front of her.

Welcome: Sinem Saka

Lab MattersPeople & Perspectives As one of EMBL’s newest group leaders, Sinem Saka will combine multiple technologies, such as microscopy and single-cell omics, to solve biological puzzles.

2021

lab-matterspeople-perspectives

23 February 2021 Two women's portraits are in circles on a greenish background

Reflecting on allyship as women in science

Lab Matters Being a woman in science takes allies, not just great science. Here, EMBL’s L’Oréal–UNESCO Fellows talk about support networks.

2021

lab-matters

23 February 2021 Greyscale image of a cell with its internal components visible

Seeing through a cell

Science & Technology Liang Xue used cryo-electron tomography to capture this detailed image of a Mycoplasma pneumoniae cell.

2021

picture-of-the-weekscience-technology

22 February 2021

Feldberg Prize for Anne Ephrussi

EMBL AnnouncementsLab Matters Anne Ephrussi has been awarded the German Feldberg Prize 2022 in recognition of her outstanding research.

2021

embl-announcementslab-matters

22 February 2021 A scientist (only their hand is visible) inserting a 96-well plate into a sample dispensing device in the Sample Preparation and Characterisation Facility in Hamburg.

SPC Facility in Hamburg supports a new pan-European consortium

ConnectionsLab Matters The Sample Preparation and Characterisation (SPC) Facility at EMBL Hamburg is one of the founding members of the Molecular-Scale Biophysics Research Infrastructure (MOSBRI). Within this new European initiative, the SPC Facility will offer services related to membrane proteins, protein complexes,…

2021

connectionslab-matters

19 February 2021 New group leader Gautam Dey looks smiling towards the camera,

Welcome to EMBL: Gautam Dey

Lab MattersPeople & Perspectives Gautam Dey is fascinated by the evolutionary origins of the nucleus, and is looking forward to making the most of EMBL's infrastructure.

2021

lab-matterspeople-perspectives

18 February 2021 Phages invading gut bacteria.

The thousands of viruses living in your gut

Science & Technology Scientists identify more than 140 000 virus species in the human gut; more than half have never been seen before

2021

sciencescience-technology

17 February 2021 Illustration of a pink capsule passing through a grey pore in a yellow membrane.

A new piece of the HIV infection puzzle explored

Science & Technology Researchers from EMBL and Heidelberg University Hospital combine high-resolution imaging to observe the infection process in cell nuclei, opening the door for new therapeutics.

2021

sciencescience-technology

16 February 2021 Microscopy images of coronavirus-infected cells in blue and red, arranged on a clockface. Illustrations of virus particles.

Finding coronavirus’s helper proteins

Science & Technology A team of EMBL scientists and colleagues have analysed how the novel coronavirus affects proteins in human cells. They identified several human proteins as potential drug targets to prevent viral replication.

2021

sciencescience-technology

16 February 2021 An assembly of proteins in an enzyme, presented in a cartoon style.

Cellular modern art

Science & Technology This week's Picture of the Week, which could also be a masterpiece of modern art, shows the enzyme RNA polymerase III, an assembly of 17 individual proteins combined into this complex structure.

2021

picture-of-the-weekscience-technology

11 February 2021 Logos of EMBL and the EMBRC.

Understanding Earth’s oceans together

ConnectionsLab Matters EMBL and EMBRC have signed a memorandum of understanding for increased scientific collaboration.

2021

connectionslab-matters

11 February 2021 Maria-Theresa Licka holding a smartphone displaying an app she developed. Vineyards, houses and hills in the background.

Coding between the vines

Lab Matters EMBL Teen Maria-Theresa Licka shares how female scientists guided & inspired her to develop an app to ID vine disease.

2021

lab-matters

9 February 2021 An artistic representation of how bioinformatics allows study of the SARS-CoV-2 infection process. On the left, coronaviruses are approaching a human face contour. On the right, protein structures and a network of connections represent bioinformatic analysis.

Protein sequences provide clues to how SARS-CoV-2 infects cells

Science & Technology Researchers at EMBL Heidelberg have identified sequences in human proteins that might be used by SARS-CoV-2 to infect cells. They have discovered that the virus might hijack certain cellular processes, and they discuss potentially relevant drugs for treating COVID-19.

2021

sciencescience-technology

9 February 2021 Roshni Mooneeram, EMBL Equality, Diversity and Inclusion Officer, strikes the #ChooseToChallenge pose with her hand high, pledging to call out bias and actively question stereotypes.

Opinion: Allyship and Women in Science

Lab Matters Roshni Mooneeram discusses what Equality, Diversity and Inclusion (EDI) is to her, and what the meaning of allyship is.

2021

lab-matters

9 February 2021 Crystal cubes seen through a microscope

Purity, beauty, and perfection

Science & Technology The regular structures of crystals are a source of inspiration and fascination to us humans. While the crystals in this picture were not grown in nature, but instead by Petra Drncova from EMBL Grenoble, they share the same attributes as those found in nature.

2021

picture-of-the-weekscience-technology

8 February 2021 Illustration of a laboratory flask to the left of a microscope against an orange/grey background with a zoomed-in cut-out of the microscope view, which is colourful molecules.

A better look at a human RNA polymerase

Science & Technology New EMBL research shows where & to what degree a component of cellular machinery known as RNA Pol III is mutated and becomes problematic.

2021

sciencescience-technology

5 February 2021 Artistic representation of the structure of the three proteins forming Integrator’s catalytic core.

At the core of the Integrator complex

Science & Technology A new paper from the Galej group at EMBL Grenoble describes the structure of key parts of the Integrator complex, involved in gene expression.

2021

sciencescience-technology

2 February 2021 A bacterial cell with the parts needed for information flow from DNA to messenger RNA to protein highlighted in different colours.

The central dogma of molecular biology

Science & Technology This colourful image shows biological information flow in action: It’s a supramolecular assembly of DNA, RNA and proteins, observed directly inside a bacterial cell while turning genetic information into protein.

2021

picture-of-the-weekscience-technology

29 January 2021 Flags of EMBL, Italy and CNR

Strengthening collaborations in Italy

ConnectionsLab Matters EMBL and CNR have signed a memorandum of understanding to strengthen scientific cooperation. The agreement will foster collaborative projects and integrate them within the European and global scientific landscape.

2021

connectionslab-matters

27 January 2021 Nicoletta Petridou looks towards the camera smiling, whilst standing in a science laboratory

Welcome: Nicoletta Petridou

Lab MattersPeople & Perspectives New group leader Nicoletta Petridou explains her fascination with the complexity of early embryo development, and how the interdisciplinary nature of EMBL will aid her research.

2021

lab-matterspeople-perspectives

26 January 2021 Two X-ray mirrors installed in the macromolecular crystallography beamline P14 at EMBL Hamburg. The mirrors are visible in the photo as dark rectangular crystal blocks, with two metal holders supporting the crystals in a stress-free position. The mirrors are inserted into a vacuum-compatible stainless steel vessel.

Mirror, mirror

Science & Technology Scientists at EMBL Hamburg use specially designed mirrors to reflect and focus X-ray beams onto tiny crystals made of proteins or other biological molecules.

2021

picture-of-the-weekscience-technology

20 January 2021

The SARS-CoV-2 B.1.1.7 lineage

Science & Technology A note on the coronavirus variant B.1.1.7, which has first been described in the U.K. and has spread to 57 countries. The note summarises epidemiological information about the spread of B.1.1.7 in the U.K. collated and in part conducted by researchers from EMBL-EBI.

2021

sciencescience-technology

20 January 2021 Logos of EMBL and the DKFZ

DKFZ and EMBL intensify cooperation

ConnectionsLab Matters EMBL and the German Cancer Research Center in Heidelberg are increasing their already existing collaborations with a Memorandum of Understanding between the two institutions.

2021

connectionslab-matters

19 January 2021 3D rendering of a human cell, attacked by a virus.

Cell under attack

Science & Technology It’s almost a year since the coronavirus outbreak was declared a pandemic, affecting all our lives. While the virus continues its grip on the world, scientists are understanding it better and better, increasing our knowledge about it and opening up new ways to fight it.

2021

picture-of-the-weekscience-technology

18 January 2021 man wearing sweater and glasses stands in front of snow and glassy building

Welcome: Timo Zimmermann

Lab MattersPeople & Perspectives The EMBL Imaging Centre is scheduled to open in 2021 with Timo Zimmermann as Team Leader for advanced light microscopy technology development and service provision.

2021

lab-matterspeople-perspectives

15 January 2021 young man with beard and mustache stands in front of window with blurry background

Welcome: Olivier Duss

Lab MattersPeople & Perspectives One of EMBL’s newest group leaders, Olivier Duss, will explore how RNA folds into functional structures and how it works with proteins to control a diverse range of activities in the cell.

2021

lab-matterspeople-perspectives

14 January 2021 An electron microscopy photo shows two bacterial cells surrounded by several white fibrils of the amphibian peptide.

Toadlet peptide transforms into a deadly weapon against bacteria

Science & Technology Researchers at the Technion – Israel Institute of Technology and EMBL Hamburg, in collaboration with scientists in Israel and Spain, have discovered remarkable molecular properties of an antimicrobial peptide from the skin of the Australian toadlet. The discovery could inspire the development of…

2021

sciencescience-technology

12 January 2021 Three images showing close-ups of different EMBL facilitites.

EMBL becomes newest Instruct Centre

ConnectionsLab Matters EMBL’s sites in Grenoble, Hamburg, and Heidelberg form the newest Instruct Centre. The new centre offers users access to a broad range of state-of-the-art facilities.

2021

connectionslab-matters

12 January 2021 A metallic tool.

Homage to a vital tool

Science & Technology Structural biologists want to study proteins at the atomic level. The device shown in this Picture of the Week is essential for this.

2021

picture-of-the-weekscience-technology

5 January 2021 colourful abstract photo with brilliant yellow-green streaks interspersed with shiny pink yellow and blue dots randomly displayed in photo

It’s like a party in your brain

Science & Technology Fluorescent dyes light up a cellular community of neurons and brain immune cells (microglia), which were derived from stem cells.

2021

picture-of-the-weekscience-technology

4 January 2021 photo of white nodule that is a kefir grain sitting in front of a milk bottle with two inset images -- one looks like yellow and tan circles, and the other is animated versions of the kefir grains

In kefir, microbial teamwork makes the dream work

Science & Technology Researchers discovered the dominant species of bacteria in kefir grains cannot endure without other species that help the 'team' survive.

2021

sciencescience-technology

22 December 2020 Eulalia clavigera. Photo credit: Marine Biological Association

Darwin Tree of Life: looking back on 2020

Science & Technology Despite restrictions, 2020 has been a busy year for the Darwin Tree of Life Project. We take a look at some of this year’s achievements and highlights.

2020

sciencescience-technology

22 December 2020

Cells in the holiday spirit

Science & Technology It is that time of year to get into the holiday spirit, prepare for some time at home and relax after a strange and stressful year. Even the cells in our Picture of the Week are getting into the holiday spirit, forming this colourful Christmas tree.

2020

picture-of-the-weekscience-technology

18 December 2020

Stronger together

Science & Technology Gene activation requires the cooperative activity of multiple transcription factors. Until now, the mechanism used by these factors to coordinate their actions has been poorly understood. EMBL’s Krebs group presents a DNA footprinting method that makes it possible to determine whether…

2020

sciencescience-technology

15 December 2020 Snowy mountains behind functional buildings. The Moon is up in the sky.

First powder over EMBL Grenoble

Lab Matters The first snowflakes have fallen on the Vercors Mountains, right behind the EMBL Grenoble building, and an almost full moon is showing up during a sunny morning.

2020

lab-matterspicture-of-the-week

11 December 2020 Woman with glasses wearing a parka stands in the snow outside a building at EMBL

EMBL Scientific Visitor Programme opens eyes and doors

EMBL AnnouncementsLab Matters Facilitated by EMBL’s Scientific Visitor Programme in 2019, Silvia Dias Almeida spent a year in the Diz-Muñoz group, helping solidify her career plans and set her up for a competitive PhD programme in biomedical imaging.

2020

embl-announcementslab-matters

9 December 2020 Illustration of a rod-shaped bacterial cell, superimposed on a red and blue background.

Heating proteins to understand how genes work

Science & Technology A new paper from EMBL’s Savitski team and Typas group describes their work on E. coli and how it brings a greater understanding of the way genes function and interact.

2020

sciencescience-technology

8 December 2020 Windowed façade reflecting leafless trees.

Clear views

Lab Matters With the external scaffolding removed, another step in the construction of the EMBL Imaging Centre is complete. Now we get a first glimpse of the final look of this stunning building.

2020

lab-matterspicture-of-the-week

7 December 2020 Female scientist stands in front of electron microscope that is taller than she is

Seeing deeper inside cells

Science & Technology While cryo-electron tomography (cryo-ET) was first envisioned in 1968, the advances the Mahamid group are bringing to this 3D method for studying molecules directly inside cells are new, and are likely to greatly expand its use.

2020

sciencescience-technology

4 December 2020 Haemoglobin protein structure shown over a matrix symbolising artificial intelligence

Solving the protein structure puzzle

Science & Technology How artificial intelligence can help us solve the mysteries of the protein universe

2020

sciencescience-technology

2 December 2020 Dark purple image with flashes of orange, gold, pink and paler purple that look a bit like lightning with a small sun-like image in the upper right section of the image

Chan Zuckerberg Initiative recognises EMBL scientists

EMBL AnnouncementsLab Matters The Chan Zuckerberg Initiative has recognised four EMBL researchers with their most recent awards, showing how tech trailblazers are integral to advancing science and medicine.

2020

embl-announcementslab-matters

2 December 2020 The image is a green coloured cell, with a wild and textured surface which is composed of many different shapes and shadows.

Scratching the surface on cell differentiation

Science & Technology Scientists in the Diz-Muñoz group at EMBL Heidelberg are working to build understanding of the role that mechanical properties play in affecting cell behaviour – a young and rapidly developing field of study. They have developed and successfully used a highly specialised technique to manipulate…

2020

sciencescience-technology

2 December 2020 Curly-shaped trypanosomes, grey with bright specks of green fluorescent protein, against a grey background.

Tackling tropical diseases

Science & Technology Members of the EMBL community are working to improve our understanding of the parasites that cause malaria and sleeping sickness

2020

sciencescience-technology

1 December 2020 The image shows the beamline P12 at EMBL Hamburg. In the centre, several cylindrical elements are connected into a pipe-like structure. In the front, it is connected to a white box-shaped device, and several smaller devices and cables visible around. There is also a grid visible around the beamline.

EMBL facilities support development of RNA vaccines

Science & Technology Biotechnology company BioNTech and Johannes Gutenberg University Mainz conduct collaborative research with EMBL scientists at the beamline P12 in Hamburg

2020

sciencescience-technology

1 December 2020 Rainbow on a cloudy sky above technical buildings.

Rainbow over the Hanseatic city

Lab Matters Hamburg hosts one of EMBL’s six sites. The city is notorious for its windy and rainy weather. Lots of rain also means a high chance of beautiful rainbows!

2020

lab-matterspicture-of-the-week

25 November 2020 The conference key visual shows a variety of species engulfed by fire, reflecting the conference title, ‘Our House Is Burning: Scientific and Societal Responses to Mass Extinction’.

Science and society: global youth activism

People & Perspectives At EMBL’s Science and Society conference, Ugandan campaigner Vanessa Nakate spoke about the need to take action on climate change.

2020

eventspeople-perspectives

24 November 2020 Red loops on a black background are dotted with bright red flecks and pale blue ovals as part of a confocal microscope image of bone marrow cells.

A loopy baseline

Science & Technology Studying cancers means also knowing what healthy cells look like. In this case, mesenchymal stromal cells (MSCs) from healthy bone marrow are a bit ‘loopy’.

2020

picture-of-the-weekscience-technology

23 November 2020 Tube-like structures of a cell at sub-cellular level in red and grey.

Replication cycle of SARS-CoV-2 in 3D

Science & Technology Researchers have studied SARS-CoV-2 replication in cells and obtained detailed insights into the alterations induced in infected cells. This information is essential to guide the development of urgently needed therapeutic strategies for suppressing viral replication and induced pathology.

2020

sciencescience-technology

23 November 2020

Statement on recent paper on mentorships in academia

EMBL AnnouncementsLab Matters EMBL’s Eileen Furlong, Chair of the Equality and Diversity Committee and Head of the Genome Biology Unit, responds to the recent Nature Comms paper on the potential effects of mentor–mentee relationships.

2020

embl-announcementslab-matters

20 November 2020 The Reichstag building (left) and Paul-Löbe-Haus (right) in Berlin, as seen in daylight from across the Spree river.

Sharing our vision for the future

ConnectionsLab Matters EMBL Director General Edith Heard introduced EMBL’s future plans during a parliamentary event at the Paul-Löbe-Haus of the German Bundestag in Berlin. She shared examples of EMBL’s research and outlined how EMBL’s activities will develop.

2020

connectionslab-matters

17 November 2020 Internal structures of the lower portion of a mouse lung display as a conical shape, displaying a variety of brilliant colours.

ARISE fellowship programme readying for applications

Lab Matters Ever-evolving technology and related budgetary, regulatory, and management challenges prompted EMBL to establish its new ARISE fellowship programme, which begins accepting applicants in December.

2020

lab-matters

17 November 2020 Car parking rooftop with a solar power plant under construction on it.

Solar power

Lab Matters Despite the cold autumn weather, workers are busy on the rooftop of the parking garage at EMBL Heidelberg. The 2176 m² rooftop is getting transformed into a combination of a green roof and a photovoltaic plant. The planted green roof will retain rainwater, while the solar panels – installed in…

2020

lab-matterspicture-of-the-week

10 November 2020 Green coloured brain cells next to a microfluidic network.

Understanding malaria

Science & Technology To help understand cerebral malaria the Bernabeu group has created in vitro engineered networks of human blood vessels.

2020

picture-of-the-weekscience-technology

4 November 2020 SARS-CoV-2 is represented as a sphere with spike proteins poking out of its surface, which give it a corona-like appearance. The spike proteins resemble triangular ‘bushes’ with three tips at the top. In the background, a cell surface is visible with ACE2 proteins poking out of it in many places. The virus is about to attach to the cell surface. The sybodies, represented as tiny V-shaped structures, bind to the viral spike proteins at their tips.

Scientists identify synthetic mini-antibody to combat COVID-19

Science & Technology By screening hundreds of sybodies (synthetic mini-antibodies), scientists have identified one that might stop SARS-CoV-2 from infecting human cells. This work, which holds promise for treating COVID-19, was conducted by EMBL Hamburg and collaborators from the Centre for Structural Systems Biology…

2020

sciencescience-technology

3 November 2020 Rainbow above the EMBL building in Heidelberg, surrounded by woods.

Under the rainbow

Science & Technology On autumn days without Heidelberg’s characteristic fog, the woods present themself in beautiful colours. You may even capture a rainbow.

2020

picture-of-the-weekscience-technology

28 October 2020 A brain hovers over a chess board, lines flow from the hypothalamus to the pieces, symbolising control over reactions to an aggressor and territory.

Should I run, or should I not? The neural basis of aggression and flight

Science & Technology Researchers in the Gross group at EMBL Rome have investigated the mechanism behind defensive behaviour in mice. They have identified a specific area of the brain that encodes both spatial and threat cues to drive location-specific defensive responses.

2020

sciencescience-technology

27 October 2020 Microscopic image of a cell, nucleus visible in bright green, cell membrane stained with a purple dye against black background.

Party at the nucleus?

Science & Technology The nucleus of this cell fluoresces in bright green thanks to GFP-labelled nucleoporin proteins. EMBL scientists use engineered nucleoporins as 3D reference standards to improve super-resolution microscopy.

2020

picture-of-the-weekscience-technology

23 October 2020 Futuristic image of deep learning schema superimposed on computer code

Bringing AI out of the black box

Lab MattersScience & Technology Why should researchers make artificial intelligence more transparent and how can they do it?

2020

lab-mattersscience-technology

22 October 2020 An artistic image of colorful wires connected to a could database.

EOSC: shaping Europe’s digital future

ConnectionsLab Matters EMBL’s Rupert Lück is engaged in developing the European Open Science Cloud (EOSC): the infrastructure that will support the future of data sharing and analysis in Europe.

2020

connectionslab-matters

20 October 2020 Open access COVID-19 data sharing

Open data sharing accelerates COVID-19 research

Science & Technology Open access data benefits millions of scientists around the world and is essential for a rapid response to the COVID-19 pandemic.

2020

sciencescience-technology

20 October 2020 Greyscale image of two sheep grazing.

Ecological lawn mowers

Lab Matters In 2012, EMBL used ecological lawn mowers to keep the grass short around the Advanced Training Centre at EMBL Heidelberg.

2020

lab-matterspicture-of-the-week

19 October 2020 Green background with white sphere bearing the logos of the two MoU signors, EMBL and CIML

EMBL forms new collaborations in France

ConnectionsLab Matters EMBL and CIML have signed a memorandum of understanding that will open up new scientific opportunities.

2020

connectionslab-matters

16 October 2020 Abstract graphic with big waves of black, white and grey somewhat like yin and yang, with two brain-shaped leaves in the upper right and lower left quadrants, one of which is green and more leafy-looking.

Taking charge by seeking ways to achieve gender balance

Lab Matters A three-day virtual conference, ‘Gender Roles and their Impact in Academia’, explored how biology, social structures, and unconscious bias shape gender roles, and discussed ways to achieve equal opportunities for men and women in academia.

2020

eventslab-matters

16 October 2020 Meytal Landau is standing next to a lab bench. On the bench, laboratory equipment is visible, such as pipettes, flasks, bottles with reagents, a calculator, and more.

Welcome: Meytal Landau

Lab MattersPeople & Perspectives New associate group leader at EMBL Hamburg investigates the structure of functional amyloids in bacteria and in human disease

2020

lab-matterspeople-perspectives

15 October 2020 Four blue circular objects are surrounded with green structures, and the central blue circle with pink structures. The blue circles are human cell nuclei, and pink and green structures are proteins.

Repurposing drugs for a pan-coronavirus treatment

Science & Technology Scientists from the Beltrao Group at EMBL-EBI and collaborators identified drug targets common to SARS-CoV-2, SARS-CoV-1, and MERS-CoV, three pathogenic coronaviruses. They also found potential drugs that could be repurposed as COVID-19 treatments, and against emerging coronavirus strains in the…

2020

sciencescience-technology

15 October 2020 Dr. Maria Arruda looks towards the camera with a serious but kind expression

Respecting diversity: the role of the scientist

Lab Matters Maria Arruda is on a mission to make scientists think more about the role they play in society. After a career in academia and the life sciences, she is trying to help others see the bigger picture when it comes to the responsibility of the scientist.

2020

eventslab-matters

14 October 2020

Seeing evolution happening before your eyes

Science & Technology Researchers from EMBL Heidelberg have established an automated pipeline to create mutations in genomic enhancers, letting them watch evolution unfold before their eyes.

2020

sciencescience-technology

13 October 2020 Molecular structure of essential light chain protein in Plasmodium glideosome. The atoms connected by bonds are symbolised by short connected lines. They are surrounded by electrons – the electron density is depicted as shapes resembling clouds. Water molecules are visible in several places as red spots. The data used to create this 3D model were obtained using X-ray crystallography at Petra III beamline, at EMBL Hamburg.

How deadly parasites ‘glide’ into human cells

Science & Technology A group of scientists led by EMBL Hamburg’s Christian Löw provide insights into the molecular structure of proteins involved in the gliding movements through which the parasites causing malaria and toxoplasmosis invade human cells.

2020

sciencescience-technology

13 October 2020 Edith Heard and Rosa Menéndez in front of the Spanish and the European flag, wearing face masks. Institute logos of EMBL and CSIC. Text: Memorandum of Understanding.

EMBL strengthens collaboration with Spanish research

ConnectionsLab Matters On 9 October, EMBL and the Spanish National Research Council (CSIC) signed a Memorandum of Understanding that paves the way for stronger collaboration between these two leading research institutions.

2020

connectionslab-matters

13 October 2020 Sea anemone polyp in side view showing two arms.

Crazy arms

Science & Technology Sea anemones are amazing creatures. Despite their plant-like appearance and their tendency to remain fixed in one spot, they are actually animals.

2020

picture-of-the-weekscience-technology

8 October 2020 Alvaro Crevenna, heads EMBL Rome’s Microscopy Facility. Credit: EMBL

Beyond the lens – microscopy at EMBL Rome

Lab MattersScience & Technology Research facilities play a crucial role in the advancement of science by supporting scientists with specialised expertise and state-of-the-art equipment. The Microscopy Facility at EMBL Rome exemplifies this role by making a wide variety of light microscopy technologies available to its researchers…

2020

lab-mattersscience-technology

6 October 2020 A series of images demonstrates the cell cycle trajectory, the first frame in each row shows a cell’s nucleus in grey. As it moves through its life cycle and enters new phases, markers change colour from red to green to pinpoint progression.

Deep learning captures cell cycle

Science & Technology Members of an EMBL-led research group with collaborators in Estonia and Russia have built and trained a deep learning model to better understand how cells grow and divide.

2020

sciencescience-technology

6 October 2020 A filmstrip showing the healing process of a wound on cellular level.

Time heals all wounds

Science & Technology We’ve all had wounds at certain times in our lives. But they heal due to the self-repairing mechanisms in the body.

2020

picture-of-the-weekscience-technology

5 October 2020 EMBL and Vilnius University logos on a background of genomic data

New partnership in Lithuania

ConnectionsLab Matters On 8 September, EMBL and Vilnius University Life Sciences Center signed a framework agreement for the establishment of the VU LSC–EMBL Partnership for Genome Editing Technologies.

2020

connectionslab-matters

1 October 2020 A group of people in an office are holding a videoconference. Some of the participants are wearing masks and gloves

Boosting the life sciences through alumni networks

Connections EMBL’s network of alumni plays a vital role in advancing the life sciences globally. EMBL provides research, services, and infrastructure that help former staff to do this effectively. For several years EMBL has been discovering more avenues to help the life sciences across Europe. A key part of…

2020

connectionsevents

29 September 2020 Oliver Billker, Director of MIMS, is standing at the podium in front of a microphone. Behind him, a projected slide says “Welcome to Umeå University”.

The Nordic EMBL Partnership: supporting national research

Connections The partnership between EMBL and four Nordic research institutions aims to stimulate scientific exchange and inspire scientific collaborations. This year’s conference of the Nordic EMBL Partnership for Molecular Medicine included many talks by EMBL researchers and a presentation by EMBL’s…

2020

connectionsevents

29 September 2020 A metal rack holding glass test tubes with yellow and red solutions in them.

Colourful test tubes

Science & Technology To study the effect of commonly used drugs on bacterial envelopes, EMBL scientists applied a biochemical assay using a colour reaction. The deeper the red, the stronger the disruptive effect of the drug.

2020

picture-of-the-weekscience-technology

24 September 2020 The conference key visual shows a variety of species engulfed by fire, reflecting the conference title, ‘Our House Is Burning: Scientific and Societal Responses to Mass Extinction’.

Dinosaurs, dodos, and the future of life on Earth

Science & Technology EMBL’s 21st Science and Society Conference will address scientific and societal responses to mass extinctions. Ahead of his keynote speech, renowned palaeontologist Mike Benton explains how looking into the deep past can give us vital insights into the future of life on Earth.

2020

eventsscience-technology

22 September 2020 Black and white electron microscope image of Anopheles mosquito gametes, looking much like feathery fern leaf stencils

A bloom of crystals

Science & Technology How does your crystal garden grow? EMBL's Electron Microscopy Core Facility was able to capture this garden of blooming crystals as they studied mosquito reproductive cells.

2020

picture-of-the-weekscience-technology

18 September 2020 Composite image of mouse cells and human cells showing different levels of luminescence, indicated as different colours.

Human and mouse cells run at different speeds

Science & Technology The internal clock that governs the development of embryos ticks slower for humans than for mice. Differences in the speed of biochemical reactions underlie the differences between species in the tempo of development.

2020

sciencescience-technology

17 September 2020 Colorful illustration conveys the balancing act women in science face, going between family and work responsibilities and wanting to succeed in both roles.

Indirect impacts of a pandemic on women in science

Lab Matters The EMBL conference that explored direct and indirect impacts from the current pandemic on women in science allowed for information and story sharing both in the form of lectures but also via online platforms like Slack and social media that included Twitter.

2020

eventslab-matters

15 September 2020 Fluorescent microscopic image of fruit fly larva with tubular heart cells in gold and the remainder of image in magenta

Fruit fly with a heart of gold

Science & Technology Not just another pretty fruit fly. This magenta and golden drosophila larva is lit up with a fluorescent molecule to help researchers study heart formation.

2020

picture-of-the-weekscience-technology

10 September 2020 Two researchers at EMBL's state-of-the-art Electron Microscopy Core Facility (EMCF). A female scientist is using a binocular microscope, a male scientist is standing next to her.

Level up!

Lab Matters ARISE fellowships to offer first-ever comprehensive training for bioscience infrastructure operations

2020

lab-matters

8 September 2020

Fighting cardiovascular disease with acne drug

Science & Technology Researchers have found the cause of dilated cardiomyopathy – a leading cause of heart failure – and identified a potential treatment for it: a drug already used to treat acne.

2020

sciencescience-technology

8 September 2020 This image shows sections of the brain organoids that have been derived from pluripotent stem cells. The increasing use of organoids like this one be key to advancing personalised medicine.

Achieving personalised therapeutics

Lab MattersScience & Technology A decadal roadmap points the way to cell-based medicine for Europe

2020

lab-mattersscience-technology

8 September 2020 A network of tubes and cells in red and blue.

Not a galaxy far, far away

Science & Technology While this may seem like a nebula made up of interstellar clouds of dust and ionised gases, this image isn’t of a galaxy beyond the Milky Way.

2020

picture-of-the-weekscience-technology

7 September 2020 Human silhouette showing internal organs including oesophagus and stomach. Circle with DNA bases A,T, C and G superimposed.

Genome sequencing accelerates cancer detection

Science & Technology The Gerstung Group at EMBL-EBI and collaborators have developed a statistical model that analyses genomic data to predict whether a patient has a high or low risk of developing oesophageal cancer.

2020

sciencescience-technology

7 September 2020 science diplomacy

Looking forward

ConnectionsLab Matters Two EMBL speakers gave presentations that looked toward the future and at ways to trailblaze on the endless frontier of science.

2020

connectionslab-matters

4 September 2020 Portrait picture of Erin Tranfield, member of the EMBL Alumni Association Board, against a blue-green background.

Supporting the alumni community

People & Perspectives Erin Tranfield recently joined the EMBL Alumni Association Board as one of 15 newly elected members. Here, she talks about her new role on the board and reflects on how a life-changing event made her refocus her perspective on work and life.

2020

alumnipeople-perspectives

3 September 2020 Left: Slice of a cell in grey. Right: Two 3D reconstructions of parts of the slice, showing the internal structure.

Nuclear pores in their natural context

Science & Technology Scientists from the Beck group have studied the 3D structure of nuclear pores in budding yeast. They show how the architecture of the nuclear pore complex differs inside cells compared to its form observed in vitro studies.

2020

sciencescience-technology

2 September 2020 Microscopy image of cerebral organoid cross section

An organoid cell atlas to enhance biomedical research

EMBL AnnouncementsLab Matters EMBL-EBI is one of the eight European institutes involved in the Humanoid Cell Atlas initiative, a new open-access platform that combines single-cell profiling and organoid technology

2020

embl-announcementslab-matters

2 September 2020 Four different evolutionary steps showing the formation and grow of tentacle arms.

Eat more to grow more arms…if you’re a sea anemone

Science & Technology An international group of researchers, led by scientists from EMBL Heidelberg, have discovered that the number of tentacle arms a sea anemone grows depends on the amount of food it eats.

2020

sciencescience-technology

1 September 2020 EMBL Fellow's Career Service

EMBL Fellows’ Career Service celebrates first birthday

EMBL AnnouncementsLab Matters As the EMBL Fellows' Career Service program reaches a milestone, it reflects on its first year and looks forward to ways to improve its offerings to EMBL postdocs and predocs.

2020

embl-announcementslab-matters

1 September 2020 larval fruit fly cells

A luminous larval love light

Science & Technology Those heart-shaped cells aren't just for show. They help tell the story of two proteins working together

2020

picture-of-the-weekscience-technology

31 August 2020 3D image of plant cells. The ones identified by the algorithm are brightly coloured.

Intelligent software tackles plant cell jigsaw

Science & Technology Starting with computer code and moving on to a more user-friendly graphical interface called PlantSeg, the Kreshuk Group at EMBL and collaborators built a simple open-access method to provide the most accurate and versatile analysis of plant tissue development to date.

2020

sciencescience-technology

26 August 2020 Colorful illustration conveys the balancing act women in science face, going between family and work responsibilities and wanting to succeed in both roles.

COVID-19’s indirect attack on women

Science & Technology More than 500 people have registered for an EMBL conference, "The impact of the COVID-19 crisis on women in science: Challenges and solutions." Scheduled for 9 September, the conference is free and open to all. Pre-registration is still available and required to attend.

2020

eventsscience-technology

25 August 2020

Training the next generation of molecular biologists

EMBL AnnouncementsLab Matters The EMBL International PhD Programme is one of EMBL’s flagship training programmes. It forms part of our efforts to train and inspire talented scientists to become skilled and creative future leaders. Submission of applications for the current PhD student recruitment round is now possible.

2020

embl-announcementslab-matters

25 August 2020 Circular beamline building, surrounded by illuminated Grenoble city in the evening and the alps in the background.

Upgraded beamlines at EMBL Grenoble unveiled

EMBL Announcements The beamlines run jointly by EMBL Grenoble and the ESRF reopen today, unveiling significant upgrades that exploit the brand new fourth generation ESRF synchrotron source.

2020

embl-announcementsscience

25 August 2020 Fruit fly larval cells looking like blue lightning

Breathing beneath the skin

Science & Technology Beautiful flashes of blue colour help light the way for researchers to study cells in fruit fly larva that provide oxygen to tissues.

2020

picture-of-the-weekscience-technology

24 August 2020 Simone Mattei, the new team leader in electron microscopy service and technology development

Welcome: Simone Mattei

Lab MattersPeople & Perspectives The new team leader offering services in electron microscopy discusses his hopes and plans for the forthcoming EMBL Imaging Centre

2020

lab-matterspeople-perspectives

20 August 2020 A portrait photo of Geetika Malhotra, new Head of Web Development at EMBL-EBI.

Welcome: Geetika Malhotra

Lab MattersPeople & Perspectives The Web Development team provides a central source of web design and development for EMBL’s European Bioinformatics Institute (EMBL-EBI). In July, Geetika Malhotra joined the team as their new Head.

2020

lab-matterspeople-perspectives

19 August 2020 A human heart sits at the centre of the illustration. The left ventricle is see-through, showing patterns of trabeculae. Around the heart are some notes from Leonardo da Vinci.

New clues to a 500-year old mystery about the human heart

Science & Technology An international team of scientists involving Ewan Birney's group has investigated the function of a complex mesh of muscle fibres that line the inner surface of the heart.

2020

sciencescience-technology

19 August 2020 An embryo of the fruit fly Drosophila.

Predicting how gene expression varies

Science & Technology Discoveries at EMBL will help researchers to interpret one of the most common types of experiments in genomics and medical studies.

2020

sciencescience-technology

18 August 2020 Three cells, each looking like a face.

Three little ghosts

Science & Technology Despite their ghostly appearance, these are very real cell nuclei infected with Influenza A virus – the only influenza virus known to cause pandemics.

2020

picture-of-the-weekscience-technology

11 August 2020 Different parts of a fruit fly arranged into an artificial green eye.

The eye of science

Science & Technology This image is a composite of lateral pentascolopidial organs, a wing imaginal disc pouch, and an epithelial wound in a Drosophila larva. The organs are arranged here like eyelashes. Cells surrounding an epidermal wound appear as the iris and pupil of this artistic eye.

2020

picture-of-the-weekscience-technology

7 August 2020 Black and white photo of Phil Avner sitting in his office and looking at his smartphone. a large stack of papers on his desk

Arrivederci Phil!

Lab MattersPeople & Perspectives As he enters retirement, Head of EMBL Rome Phil Avner reflects on his scientific career and memories from his time as Head of EMBL’s site in Italy

2020

lab-matterspeople-perspectives

6 August 2020 Logo of the European Laboratory for Learning and Intelligent Systems. Left: A chalkboard drawing of Europe. Right: the letters E L L I S in different colours.

Bridging artificial intelligence and the life sciences – launch of ELLIS Heidelberg

Lab MattersScience & Technology Researchers from all life science disciplines – from fundamental biological research to medical applications – generate immense datasets. Analysing these datasets and gaining new knowledge from them is a growing challenge for scientists. The fields of artificial intelligence (AI) and machine…

2020

lab-mattersscience-technology

5 August 2020 The tuatara, an iguana-like reptile with a crest of spikes, sits on a forest floor.

The curious genome of the tuatara, an ancient reptile in peril

Science & Technology A global team of researchers including the Flicek Team at EMBL-EBI has partnered up with the Māori tribe Ngātiwai to sequence the genome of the tuatara, a rare reptile endemic to New Zealand.

2020

sciencescience-technology

4 August 2020 A long string of cells - red in the centre, yellow at the border.

Fish close-up

Science & Technology This group of cells represents an interesting example of organ formation where cells simultaneously move and change their shapes in a highly coordinated manner.

2020

picture-of-the-weekscience-technology

3 August 2020 A woman with glasses holds a book. The book cover says "Gene naming rules". Thought bubbles float around her head and display gene symbols like BRCA1.

Bagpipe and Pokemon, or how not to name a human gene

Science & Technology The human genome harbours about 19 000 protein-coding genes, many of which still have no known function. As scientists unveil the secrets of our DNA, they come across novel genes that they need to refer to using a unique name. The Human Genome Organisation’s Gene Nomenclature Committee (HGNC) at…

2020

sciencescience-technology

31 July 2020 This visual representation shows the newly identified architecture (left) of the coupled molecular machines responsible for transcription (green; DNA in magenta) and translation (blue and yellow), accompanied by the protein interaction network from mass spectrometry (centre) and the cryo-electron tomography data (right) from Mycoplasma pneumoniae that was used to model the structure. Credit: Liang Xue and Julia Mahamid/EMBL

Visualising the cell’s molecular machinery in action

Science & Technology A new approach that allows researchers to see molecular machinery at work inside cells has offered a deeper understanding of how bacteria produce proteins and a unique glimpse into how they respond to antibiotics.

2020

sciencescience-technology

29 July 2020 Screenshot from the online SAXS course. Clement Blanchet, a senior scientist in the Svergun group at EMBL Hamburg, is presenting the P12 SAXS beamline at Petra III to the participants.

EMBL releases online course on solution scattering from biological macromolecules

EMBL Announcements The Svergun group at EMBL Hamburg has released the course ‘Solution Scattering from Biological Macromolecules’ in an online format for the first time. The course explores different aspects of small-angle X-ray scattering (SAXS) for studying the structure of macromolecules.

2020

embl-announcementsevents

28 July 2020 Atomic model of the entire condensin complex

Understanding chromosome organisation

Science & Technology EMBL scientists and collaborators help reveal the process by which enormous quantities of DNA are folded into cells.

2020

sciencescience-technology

28 July 2020 Small dots. Some in bright yellow.

An ocean of droplets

Science & Technology Bacterial cells are embedded in microfluidic droplets in oil. The fluorescence indicates the presence of the targeted DNA strain with the help of a characteristic DNA sequence.

2020

picture-of-the-weekscience-technology

27 July 2020 Mosaic of microscopy images of tumour, forming two broken DNA molecules

Artificial intelligence finds patterns of mutations and survival in tumour images

Science & Technology Researchers have developed an artificial intelligence algorithm that uses computer vision to analyse tissue samples from cancer patients. The algorithm can distinguish between healthy and cancerous tissues, and can also identify patterns DNA and RNA changes in tumours.

2020

sciencescience-technology

21 July 2020 A row of ceiling windows

A bright view of the future

Science & Technology The image shows one of the four rows of roof lights above the atrium, which is the main public space of the Imaging Centre.

2020

picture-of-the-weekscience-technology

21 July 2020 Top row: The evolution of tumour cells (green) within a normal organoid (grey) shown in three panels. Lower row: Surface rendition of tumour cells and labels new cells that arise from a single cell in the same colour.

A tool to improve cancer research

Science & Technology EMBL scientists have created a new, realistic 3D testbed that could help achieve the goal of stopping cancers before they start by studying cancer cells as they first form.

2020

sciencescience-technology

20 July 2020 A magnifying glass hovers over the human gut, revealing its biodiversity.

Unparalleled inventory of the human gut ecosystem

Science & Technology An international team of scientists has collated all known bacterial genomes from the human gut microbiome into a single large database. Their work will allow researchers to explore the links between bacterial genes and proteins, and their effects on human health.

2020

sciencescience-technology

16 July 2020 A collage of portrait photos of Jessica Vamathevan, Jan Korbel, and Nassos Typas.

Changes in senior roles at EMBL

EMBL AnnouncementsLab Matters Three changes in senior staff positions have been confirmed at EMBL today. Jessica Vamathevan becomes Head of Strategy, Jan Korbel becomes Head of Data Science for EMBL Heidelberg, and Nassos Typas becomes Senior Scientist.

2020

embl-announcementslab-matters

14 July 2020 The image shows a larva of Platynereis dumerilii, a marine worm. The body of the worm is shown in grey. Muscle strands are coloured in red. The muscles of one individual strand are highlighted in different, brighter colours.

Muscular worm larva

Science & Technology The image shows a larva of Platynereis dumerilii, a marine worm. The image here was produced by Constantin Pape, a visiting predoctoral fellow in the Kreshuk group at EMBL Heidelberg.

2020

picture-of-the-weekscience-technology

13 July 2020 scientists teaching about the microbiome

Applications for virtual learning lab open

Lab Matters The European Learning Laboratory for the Life Sciences (ELLS), EMBL’s education facility, invites secondary school science teachers to participate in a virtual training course this autumn entitled ‘Introducing your microbiome’.

2020

lab-matters

8 July 2020 The national flag of Latvia: A carmine field bisected by a narrow white stripe (one-fifth the width of the flag)

Latvia becomes EMBL prospect member state

EMBL AnnouncementsLab Matters Latvia has joined EMBL as a prospect member, starting a three-year process toward full membership.

2020

embl-announcementslab-matters

8 July 2020 Alexander Aulehla on the left and Paul Flicek on the Right

Two EMBL scientists become EMBO Members

EMBL AnnouncementsLab Matters This year, EMBO elected 63 new members, including Alexander Aulehla, Group Leader and Senior Scientist at EMBL Heidelberg, and Paul Flicek, Associate Director of EMBL-EBI Services, Senior Scientist, Group and Team Leader at EMBL-EBI.

2020

embl-announcementslab-matters

8 July 2020 The Logo of the ALPX company.

ALPX – smart crystallography

Lab Matters The CrystalDirect® technology, combined with the web-based CRIMS software enable a fully automated, remote-controlled protein-to-structure pipeline.

2020

lab-matters

8 July 2020 Artwort illustrating various aspects of infection research. The centre of the image shows a cartoon representation of a coronavirus. The spheric shape has been overlaid with a map of the world to illustrate the global spread of viruses. The edges of the artwork feature images of potential virus hosts (bats, poultry, dromedary), a group of humans, a microscope, pills, a syringe and vaccine vial, protein structures, and an illustration of a human lung. The background is set in yellow and red colour.

What COVID-19 is teaching us

Science & Technology The virtual EMBL Conference ‘SARS-CoV-2: Towards a New Era in Infection Research’ explored the importance of fundamental research, collaboration, and data science in containing the SARS-CoV-2 pandemic, and discussed opportunities to improve our response to pandemics in the future.

2020

eventsscience-technology

7 July 2020 The rainbow pride flag hanging in front of the Advanced Training Centre at EMBL Heidelberg. Picture taken in summer 2020.

Pride at EMBL

Lab Matters EMBL brings together more than 1700 people from all over the world, from a variety of academic and cultural backgrounds. This creates an environment in which there is constant exchange of both scientific knowledge and cultural heritage. While it seems obvious that EMBL, as an international…

2020

lab-matterspicture-of-the-week

6 July 2020 EMBL Director General Edith Heard standing at a laboratory work bench, facing the camera. Edith Heard on the left side, lab bench with pipettes and equipment on the right. Photo taken by érôme Brébion at Institut Curie, Paris.

Edith Heard elected senator of the Max Planck Society

EMBL AnnouncementsLab Matters EMBL Director General Edith Heard has been elected a senator of the Max Planck Society, one of Germany’s leading scientific research organisations. She joins the Senate along with Nobel Laureates and EMBL alumni Christiane Nüsslein-Volhard and Stefan W. Hell, as well as nine additional new…

2020

embl-announcementslab-matters

3 July 2020 stem cells neurons differentiation

From stem cells to neurons

Science & Technology Scientists at EMBL Heidelberg have investigated stem cells and how they differentiate to become neurons. Their approach included an assessment of the complex interplay of molecules during the differentiation process and generated fundamental new insights into the role of a protein called Sox2 in…

2020

sciencescience-technology

2 July 2020 Edith Heard

Restructure of senior management

EMBL AnnouncementsLab Matters The governing Council of EMBL has approved Director General Edith Heard’s restructure of senior management with effect from 1 July 2020.

2020

embl-announcementslab-matters

2 July 2020 epigenetic reprogramming, epigenetic memory, Hackett group

Unravelling epigenetic reprogramming

Science & Technology A study conducted by the Hackett group at EMBL Rome has identified key factors controlling the complex system of gene regulation during early embryo development, shedding new light on the mechanisms behind these events and on their evolutionary implications. Their findings are published in Nature…

2020

sciencescience-technology

1 July 2020 New Informatics Science Director at Open Targets, Ellie McDonagh

Welcome: Ellie McDonagh

Lab MattersPeople & Perspectives Open Targets welcomes new Informatics Science Director

2020

lab-matterspeople-perspectives

30 June 2020

EMBL boosts national and international sharing of genomic data

ConnectionsLab Matters A national consortium including EMBL and the DKFZ is set to launch the German Human Genome–Phenome Archive, creating an invaluable bridge between fundamental biomedical research and applied healthcare.

2020

connectionslab-matters

30 June 2020 Beekeeper checking one of the hives near the Adacned Training Centre at EMBL Heidelberg.

Busy bees at the ATC

Lab Matters Local beekeeper Jörg Staffel has set up three bee colonies on the grass slope in front of the ATC building.

2020

lab-matterspicture-of-the-week

29 June 2020 Gene Editing and Embryology Facility at EMBL Rome

Editing the mouse genome to study SARS-CoV-2 infection

Science & Technology To study how SARS-CoV-2 infects cells, the Gene Editing and Embryology Facility (GEEF) at EMBL Rome will generate mice that express a human version of a protein called ACE2. The mouse line will be shared with preclinical research collaborators carrying out vaccine and antibody trials, and with the…

2020

sciencescience-technology

26 June 2020 Key visual for ‘Life Science Across the Globe’

Sharing our passion for science with the world

Lab Matters EMBL is joining the virtual seminar series ‘Life Science Across the Globe’ – a timely initiative to foster international scientific exchange across countries and continents, starting on 1 July.

2020

lab-matters

25 June 2020 Scientists in the Hackett group at EMBL Rome doing lab work

Silencing the SARS-CoV-2 receptor with epigenetic modifications

Science & Technology EMBL scientists develop a new molecular tool to prevent SARS-CoV-2 infection in mice. This tool is able to cause targeted epigenetic modifications of specific genes in specific cell populations. They will use it in mice to target airway cells that express the ACE2 protein – the receptor that…

2020

sciencescience-technology

24 June 2020 Artist's impression of DNA lesions. Credit: Petra Korlevic

Unpicking the complexity of DNA mutations

Science & Technology DNA damage caused by chemical mutagens is not repaired immediately and can create more genetic diversity in tumours.

2020

sciencescience-technology

23 June 2020 EMBL's Equality and Diversity Officers. Zac O'Sullivan (left) and Luisa Vieites Rodrigues (right)

Equality and diversity at EMBL

Lab Matters EMBL is striving to make its labs and offices a welcoming and inclusive environment for all. To achieve this goal, EMBL's Equality and Diversity Officers, Luisa Vieites Rodrigues and Zac O'Sullivan, are working closely with leadership and the EMBL community. In this interview, they share their…

2020

lab-matters

23 June 2020

Delicious science

Lab Matters Elisa Kreibich from EMBL’s Krebs group baked an EMBL cake for the farewell of Alexandra Martitz, the first master student in their lab.

2020

lab-matterspicture-of-the-week

18 June 2020 Illustration of gender balances in academia

Closing the gender gap

EMBL Announcements To explore the origins of gender imbalances in academia and possible ways of overcoming them, international experts will meet for the virtual EMBL | EMBO | HHMI conference ‘Gender Roles and their Impact in Academia’ from 13–15 Oct 2020. The conference’s outcomes will be integrated into a…

2020

embl-announcementsevents

17 June 2020 Crystal selection for X-ray diffraction experiments.

Investigating the structure and mechanisms of coronavirus biomolecules

Science & Technology While global research on coronaviruses has shed light on the function of many SARS-CoV-2 proteins, the role of some crucial components remains unknown. Researchers at EMBL Grenoble will use a range of structural biology methods to try to solve some of the puzzles of the molecular mechanics of…

2020

sciencescience-technology

16 June 2020 Tissue culture plates in an incubator.

Understanding how SARS-CoV-2 behaves in the gut

Science & Technology Scientists at EMBL and Heidelberg University Hospital are studying how the novel coronavirus behaves in the gut to try to better understand its epidemiology and prevent its spread. To do this, they are combining advanced imaging and sequencing technologies to study coronavirus in human intestinal…

2020

sciencescience-technology

16 June 2020 Composite image of fly larvae organs making up a flower

From fly to flower

Science & Technology In this composite image, visual artist Mona Kakanj assembled three different biological structures in fly larvae into a flower. The original images were taken as part of a research project by Parisa Kakanj in Maria Leptin’s group.

2020

picture-of-the-weekscience-technology

15 June 2020 Arise logo

Life sciences open their doors for engineers

Lab Matters The European Molecular Biology Laboratory has secured 6.8 million Euros funding from the European Commission to launch a unique training programme. The ARISE Programme will train and develop Europe’s next generation leadership for research infrastructures in the life sciences.

2020

lab-matters

15 June 2020 Key visual for the virtual EMBL conference ‘SARS-CoV-2: Towards a New Era in Infection Research’. Credits: Aleksandra Krolik/EMBL

Improving our response to emerging pandemics

EMBL Announcements The emergence of previously unknown pathogens, such as the novel coronavirus SARS-CoV-2, raises many questions. To explore these questions in an international scientific forum, EMBL will host the virtual conference ‘SARS-CoV-2: Towards a New Era in Infection Research’ on 3 July. Invited…

2020

embl-announcementsevents

12 June 2020

Blood pressure drug improves response to cancer therapy

Science & Technology Scientists discovered that antihypertensive agent alters the tissue characteristics of colon cancer metastases. This "stiffness" of metastases has an effect on the therapeutic success.

2020

sciencescience-technology

9 June 2020 This image shows the structure of a bacterial group II intron

Genetic cut and paste at atomic resolution

Science & Technology Researchers in the Marcia group at EMBL Grenoble and the De Vivo lab at the Italian Institute of Technology in Genoa have obtained some of the most detailed ever snapshots of the splicing process in systems known as group II self-splicing introns. The new insights will help scientists to develop…

2020

sciencescience-technology

9 June 2020 Beamline Hamburg

Shining high-brilliance beams on coronavirus structure

Science & Technology EMBL researchers are studying COVID-19-related molecules by exposing them to high-brilliance X-ray beams. The Svergun group at EMBL Hamburg is using biological small-angle X-ray scattering (SAXS) as part of a global effort by scientists to elucidate the structural organisation of SARS-CoV-2…

2020

sciencescience-technology

9 June 2020 Mouse embryonic fibroblasts and their cell skeletons

Glow-in-the-dark cell skeletons

Science & Technology This image shows mouse embryonic fibroblasts (MEFs), their cell skeletons (green) and nuclei (blue) under a confocal microscope, photographed by Julia Hansen in the lab of Matthieu Boulard at EMBL Rome.

2020

picture-of-the-weekscience-technology

8 June 2020 Microscopic image showing a macrophage that has been infected with Salmonella (green), causing cellular cathepsins (red) to locate to the nucels (blue).

Re-trafficking proteins to fight Salmonella infections

Science & Technology Scientists including members of EMBL’s Typas group have investigated how immune cells called macrophages respond to infection by the intracellular pathogen Salmonella enterica. They discovered that Salmonella causes newly produced cathepsins to accumulate in the nuclei of infected cells to…

2020

sciencescience-technology

2 June 2020

Organelles in space

Science & Technology This image is a 3D-rendering of the automatic segmentation of a HeLa cell, made by Julian Hennies from the Schwab team at EMBL Heidelberg.

2020

picture-of-the-weekscience-technology

1 June 2020 An illustration of single-cell RNA sequencing (scRNA-seq)

Enabling functional genomics studies in individual cells

Science & Technology Scientists at EMBL Heidelberg have developed a new method, called Targeted Perturb-seq (TAP-seq), which increases the scale and precision of functional genomics CRISPR–Cas9 screens by orders of magnitude. Their method overcomes limitations in previous applications of single-cell RNA sequencing,…

2020

sciencescience-technology

27 May 2020 Automated sample changer and diffractometer at the ID30B X-ray crystallography beamline at ESRF Grenoble.

Facilitating COVID-19 structural biology research

Connections EMBL and the European Synchrotron Radiation Facility (ESRF) restart the activities of the Joint Structural Biology Group in Grenoble to support coronavirus-related projects. A new initiative will allow users to be granted access to the High-Throughput Crystallisation (HTX) lab at EMBL and to a…

2020

connectionsscience

26 May 2020 Bioinformatic analysis of over 4700 SARS-CoV-2 genomes revealed that many of the most interesting changes in the SARS-CoV-2 genome that have been reported so far are likely to be technical artefacts, rather than biological mutations.

Distinguishing coronavirus genome mutations from inadvertent errors

Science & Technology EMBL scientists have performed a large-scale analysis of over 4700 SARS-CoV-2 genome sequences. They found that many of the most interesting changes in the SARS-CoV-2 genome that have been reported so far are likely to be technical artefacts, rather than biological mutations.

2020

sciencescience-technology

26 May 2020

Underwater butterfly

Science & Technology In the Leptin Group, Eva Hasel investigates the innate immune system in Japanese rice fish.

2020

picture-of-the-weekscience-technology

22 May 2020

The hunt for neutralising antibodies against SARS-CoV-2

Science & Technology Scientists hope that a legacy of the novel coronavirus in recovered COVID-19 patients – antibodies in their blood – could lead to drugs to treat others. The Merten group at EMBL Heidelberg has pivoted its microfluidics platform to support the search for neutralising antibodies that could…

2020

sciencescience-technology

22 May 2020

EMBL scientists investigate rare lung disease

Science & Technology Researchers in EMBL’s Zaugg group have studied the causes of pulmonary arterial hypertension (PAH), a rare disease that causes high blood pressure in the arteries of the lungs. The study, carried out in collaboration with Stanford University School of Medicine, compared lung cells of patients…

2020

sciencescience-technology

19 May 2020 EMBL group leader Georgia Rapti

Welcome: Georgia Rapti

Lab MattersPeople & Perspectives The nervous system has fascinated Georgia Rapti ever since her first introduction to biology. Her research group in the Developmental Biology unit will focus on understanding the early biological events involved in the nervous system’s formation.

2020

lab-matterspeople-perspectives

19 May 2020

The birth of tentacles

Science & Technology The image shown here, taken by Anniek Stokkermans from EMBL’s Ikmi Group, shows a larva of Nematostella vectensis.

2020

picture-of-the-weekscience-technology

15 May 2020 Cell division

Tracing the origins of cells

Science & Technology Researchers from the Sharpe group at EMBL Barcelona have published a method to track the developmental history of a cell using the gene editing tool CRISPR–Cas9, but without the need to create transgenic organisms.

2020

sciencescience-technology

14 May 2020 NetApp logo

EMBL welcomes NetApp in its Corporate Partner Programme

ConnectionsLab Matters EMBL welcomes NetApp, a leader in cloud data services empowering global organisations to change their world with data, as member of the Corporate Partnership Programme of the EMBL Advanced Training Centre.

2020

connectionslab-matters

13 May 2020 Close-up photograph of servers at EMBL Heidelberg's data centre.

Understanding the role of our genes in SARS-CoV-2 infections

Science & Technology EMBL scientists will contribute to the new German COVID-19 OMICS Initiative to study the biological mechanisms contributing to coronavirus infections. EMBL group leaders Jan Korbel and Oliver Stegle, who is also affiliated with the DKFZ Heidelberg, will coordinate the set-up of IT infrastructures…

2020

sciencescience-technology

12 May 2020

Shine like an underwater star

Science & Technology This image of the starlet sea anemone was taken by Petrus Steenbergen using a stereoscope.

2020

picture-of-the-weekscience-technology

11 May 2020

EMBL SPC facility supports COVID-19 projects

Science & Technology The Sample Preparation and Characterisation Facility (SPC) at EMBL Hamburg reopens to support scientists working on Covid-19 research. The SPC Facility is one of the best equipped facilities in Europe is therefore in high demand from external users. Re-opening the facility also allows experts at…

2020

sciencescience-technology

6 May 2020

Wings without wings

Science & Technology The image shown here, taken by Daniel Rios-Barrera from the Leptin Group shows the cells of the early wing tissue of the fly during larval development.

2020

picture-of-the-weekscience-technology

5 May 2020 Liquid handling robot transfering protein crystalisation solutions

Responding to health threats posed by coronaviruses

Science & Technology By re-opening the High-Throughput Crystallisation (HTX) lab at EMBL Grenoble, EMBL is supporting structural biology projects to respond to the health threats posed by coronaviruses.

2020

sciencescience-technology

4 May 2020

Nordic EMBL Partnership awarded €210,000 funding

ConnectionsLab Matters The Nordic EMBL Partnership for Molecular Medicine has been awarded 210,000 euros. The funds will be used to train the next generation of specialists and research leaders in molecular medicine in the Nordic countries.

2020

connectionslab-matters

29 April 2020 The Influenza virus

Understanding the influenza virus

Science & Technology The infectious disease commonly known as flu is caused by the influenza virus. It spreads around the world in seasonal outbreaks, causing millions of infections and hundreds of thousands of deaths each year. Stephen Cusack, Head of EMBL Grenoble, has been studying different aspects of the influenza…

2020

sciencescience-technology

28 April 2020

Dancing chromosomes

Science & Technology In human cells, the genetic material is packaged into 23 different DNA molecules, the chromosomes. Each chromosome is present in two copies, one inherited from the paternal sperm, and the other from the maternal egg. During most of the cell’s life, chromosomes take the shape of long,…

2020

picture-of-the-weekscience-technology

28 April 2020 Close-up view of the interior of a protein analytics system

Exploring synthetic antibodies to stop coronavirus

Science & Technology Scientists at EMBL Hamburg and Karolinska Institutet Stockholm aim to find synthetic antibodies – known as nanobodies – that bind a surface protein of the novel SARS-CoV-2 coronavirus. Nanobodies could prevent the virus from entering human cells and causing COVID-19.

2020

sciencescience-technology

27 April 2020 Artistic rendering of an RNA-binding protein interacting with an RNA molecule.

Helping researchers identify host proteins used by coronavirus

Science & Technology EMBL scientists working in the groups of Matthias Hentze and Wolfgang Huber have created RBPbase – a database of RNA-binding proteins – to assist the identification of proteins that interact with the SARS-CoV-2 RNA genome.

2020

sciencescience-technology

24 April 2020 Collage of images representing wet and dry lab research and healthcare

Why share data during a pandemic?

Science & Technology In March 2020, planes were grounded, streets went quiet, and our lives changed forever. But while the world came to a halt, many scientists were ramping up their efforts to understand the new virus.

2020

sciencescience-technology

23 April 2020 Key visual for the EMBO | EMBL symposium ‘The Four-Dimensional Genome’

EMBL hosts its first virtual conference

Lab Matters The virtual EMBO | EMBL symposium ‘The Four-Dimensional Genome’ brought together 470 participants. Here, Jürgen Deka, Head of External Scientific Training, discusses how he and his team overcame the organisational challenges.

2020

eventslab-matters

22 April 2020 Earth Day 2020 logo

EMBL statement on Earth Day 2020

EMBL AnnouncementsLab Matters To address global challenges, we need to better understand life in the context of environmental change, says EMBL Director General Edith Heard

2020

embl-announcementslab-matters

22 April 2020 Portrait photo of Brendan Rouse, EMBL's Environmental Officer

Welcome: Brendan Rouse

Lab MattersPeople & Perspectives Brendan Rouse came to Heidelberg in March as EMBL’s Environmental Officer, tasked with monitoring the organisation’s environmental impact and promoting sustainable practices. Here, he discusses his plans for the new role.

2020

lab-matterspeople-perspectives

21 April 2020

Evolution of the eye

Science & Technology This Picture of the Week shows a stained cryosection of a retina – the light-sensitive part of the eye – of an ancient fish, the lamprey.

2020

picture-of-the-weekscience-technology

20 April 2020 A 4D visualisation of single-cell expression patterns. Credit: Hanna Sladitschek/EMBL

Unprecedented single-cell studies in virtual embryo

Science & Technology Researchers from EMBL Heidelberg have created a complete description of early embryo development, accounting for every single cell in the embryo.

2020

sciencescience-technology

20 April 2020 COVID-19 Data Portal logo on globe background

EMBL-EBI launches COVID-19 Data Portal

Science & Technology The new collaborative space will help scientists, public health and healthcare professionals around the world to fight the coronavirus pandemic.

2020

sciencescience-technology

16 April 2020 Micropipette tips in a liquid-handling robot

Helping to scale up coronavirus testing

Science & Technology Scientists at EMBL Heidelberg are contributing their expertise in a community effort to develop large-scale testing methods for coronavirus. Their goal is to increase the capacity and speed of testing, which is crucial for containing the pandemic.

2020

sciencescience-technology

15 April 2020 Purified proteins on an SDS-polyacrylamide gel

Producing proteins for coronavirus research

Science & Technology The Protein Expression and Purification Core Facility at EMBL Heidelberg will produce proteins for several coronavirus-related research projects, to assist the development of new strategies to fight the virus.

2020

sciencescience-technology

14 April 2020

Gazing at healing wounds

Science & Technology What may look like a branch of a tree with the first flower buds emerging after winter are, in fact, tracheal cells of a fruit fly larva and their nuclei.

2020

picture-of-the-weekscience-technology

9 April 2020 3D reconstruction of parental chromosomes in the mouse embryo

How chromosome structure influences development

Science & Technology EMBL researchers in the Heard group at EMBL Heidelberg explore the interaction between DNA organisation and gene expression in the early embryo

2020

sciencescience-technology

7 April 2020

Exciting science!

Science & Technology EMBL is all about exciting science, through which we aim to achieve a fundamental understanding of biological processes.

2020

picture-of-the-weekscience-technology

2 April 2020 Map showing institutes involved with EMBL in Twinning projects

EMBL shares expertise with four European institutes

ConnectionsLab Matters Three international teams involving EMBL Heidelberg have been granted funding from the European Commission for three Twinning projects with institutes in Portugal and the Czech Republic.

2020

connectionslab-matters

1 April 2020

Understanding brain tumours in children

Science & Technology The causes of 40 percent of all cases of certain medulloblastoma – dangerous brain tumours affecting children – are hereditary. These are the findings of a recent genetic analysis carried out by scientists from EMBL and numerous colleagues around the world.

2020

sciencescience-technology

31 March 2020 Portrait of Bastian Drees, Head of Library

Welcome: Bastian Drees

Lab MattersPeople & Perspectives Bastian Drees is a biophysicist turned librarian, who joined EMBL in January as the new Head of Library. Here, he discusses the changing role of libraries and how they can help scientists organise and share their results.

2020

lab-matterspeople-perspectives

31 March 2020

Artistic life sciences

Science & Technology Paola Bertucci, from the Arendt Group at EMBL Heidelberg, studies the evolution of Platynereis dumerilii – a species of annelid polychaete worm.

2020

picture-of-the-weekscience-technology

24 March 2020

Springtime in Heidelberg

Lab Matters The iconic ATC – celebrating its 10 year anniversary this year – reflects the blue sky, the clouds and the rays of the Sun.

2020

lab-matterspicture-of-the-week

17 March 2020

Wrapped in purple

Science & Technology The medaka shown in this Picture of the Week was captured by Eva Hasel, a postdoc in the Leptin group at EMBL Heidelberg.

2020

picture-of-the-weekscience-technology

11 March 2020 Leukaemia stem cells are located in a patient’s bone marrow (shown here in blue) in the so-called stem cell niche. The green structure is the bone itself. Credit: Dr. Raphael Lutz, Haas Lab

€2.45 m to investigate leukaemia causes and therapies

EMBL Announcements The Heidelberg-based LeukoSyStem consortium investigates leukaemia stem cells in acute myeloid leukaemia. The German Federal Ministry of Education and Research financially supports this collaboration between Heidelberg University Hospital, HI-STEM gGmbH, the German Cancer Research Center and EMBL.

2020

embl-announcementsscience

10 March 2020

It’s Lab Ski Day!

Lab Matters This image, taken by Raphaël Cohen-Aberdam from the Cipriani team, shows that the weather for the Grenoble Lab Ski Day 2020 was just perfect!

2020

lab-matterspicture-of-the-week

5 March 2020

New insights into gene regulation

Science & Technology EMBL researchers investigate the role of a histone protein in regulating gene expression

2020

sciencescience-technology

3 March 2020

Snowy day

Lab Matters Colder winter weather has finally arrived EMBL-EBI. It’s the first time the site has seen snow this winter.

2020

lab-matterspicture-of-the-week

25 February 2020

Accidental beauty

Science & Technology In the Trivedi Group at EMBL Barcelona, Krisztina Arató and Jia Le Lim study the early development of zebrafish embryos.

2020

picture-of-the-weekscience-technology

20 February 2020 lucia-von-bredow

Welcome: Lucia von Bredow

Lab MattersPeople & Perspectives EMBL’s new Science and Society Manager shares her plans for fostering multidisciplinary dialogue

2020

lab-matterspeople-perspectives

19 February 2020 Claire Deo

Welcome: Claire Deo

People & Perspectives New group leader at EMBL Heidelberg employs synthetic chemistry to develop novel tools for biology

2020

people-perspectivesscience

18 February 2020

Mapping space inside the cell

Science & Technology In this image, Julian Hennies from the Schwab Team has reconstructed the 3D structure of a human cell's organelles.

2020

picture-of-the-weekscience-technology

11 February 2020

Breathe in, breathe out

Science & Technology This image shows the tracheal system of a live fruit fly larva. Daniel Rios from the Leptin Group and Dimitri Kromm from the Hufnagel Group used this advanced microscope to investigate the dynamics of tracheal cells during development.

2020

picture-of-the-weekscience-technology

5 February 2020

The Pan-Cancer project

Science & Technology EMBL co-leads most comprehensive study of genetic causes of cancer

2020

sciencescience-technology

5 February 2020

Protecting data in the cloud

Science & Technology Cloud computing offers unprecedented opportunities for global-scale research collaborations. It also presents a unique set of challenges in terms of data protection and the ethics of data sharing.

2020

sciencescience-technology

5 February 2020

Characterising RNA alterations in cancer

Science & Technology The largest and most comprehensive catalogue of cancer-specific RNA alterations reveals new insights into the cancer genome.

2020

sciencescience-technology

5 February 2020

Cancer mutations occur decades before diagnosis

Science & Technology Researchers at EMBL’s European Bioinformatics Institute (EMBL-EBI) and the Francis Crick Institute have analysed the whole genomes of over 2600 tumours from 38 different cancer types to determine the chronology of genomic changes during cancer development.

2020

sciencescience-technology

5 February 2020

Analysis of human genomes in the cloud

Science & Technology Scientists from EMBL present a tool for large-scale analysis of genomic data with cloud computing. Main advantages of the new tool, called Butler, are continuous system monitoring and its ability to self-heal in case of failure, allowing for 43% more efficient data processing than previous…

2020

sciencescience-technology

5 February 2020

Studying DNA rearrangement to understand cancer

Science & Technology Using the dataset from the Pan-Cancer project, scientists has developed methods to group, classify, and describe large rearrangements of the genome that are a key driver of cancer.

2020

sciencescience-technology

5 February 2020

Chromothripsis in human cancer

Science & Technology Researchers at Harvard Medical School and EMBL-EBI have carried out the largest analysis across cancer types of the newly discovered mutational phenomenon chromothripsis.

2020

sciencescience-technology

5 February 2020

Finding genetic cancer risks

Science & Technology Using the data from the Pan-Cancer project EMBL scientists describe how our genetic background influences cancer development.

2020

sciencescience-technology

4 February 2020 Mouse genetic data identifies rare disease genes

Pinpointing rare disease mutations

Science & Technology New resource that categorises genes essential for supporting life could be used to identify rare disease mutations

2020

sciencescience-technology

4 February 2020

From cosmetics to blood cells

Science & Technology Morgan Oatley and her colleagues in Christophe Lancrin’s group investigated how haematopoietic stem cells emerge from the endothelium in developing mouse embryos.

2020

picture-of-the-weekscience-technology

31 January 2020

Statement on Brexit

EMBL AnnouncementsLab Matters Today marks the next chapter in the UK’s relationship with Europe. While we wait to see what a future relationship brings, researchers will continue to work across borders to tackle society’s most pressing problems, such as climate change, ageing, and disease.

2020

embl-announcementslab-matters

28 January 2020

Injured lung

Science & Technology Muzamil Majid Khan, a postdoc in the Pepperkok team at EMBL Heidelberg, studied the piece of tissue visible in this image.

2020

picture-of-the-weekscience-technology

27 January 2020 Maria Bernabeu

Welcome: Maria Bernabeu

People & Perspectives New group leader at EMBL Barcelona is investigating how malaria affects the human circulatory system

2020

people-perspectivesscience

24 January 2020

Hungarian Minister visits EMBL

Connections László Palkovics, Hungarian Minister for Innovation and Technology, visited EMBL Heidelberg

2020

connectionsevents

22 January 2020

Antibody engineering for therapy and diagnosis

Lab MattersScience & Technology The new EMBL spinoff company Araxa Biosciences GmbH aims to set new standards for the development of antibody-based therapeutics and diagnostics

2020

lab-mattersscience-technology

21 January 2020 Janet Thornton EMBL Insight Lecture

Ageing and disease

Science & Technology Dame Janet Thornton presents the 2019 EMBL Insight Lecture: Ageing and disease – what is the link?

2020

eventsscience-technology

21 January 2020 Kristina Haase

Welcome: Kristina Haase

People & Perspectives Kristina Haase brings an engineer’s perspective to vascular disease and regenerative medicine

2020

people-perspectivesscience

21 January 2020

Judith Reichmann receives Paul Ehrlich prize

EMBL AnnouncementsLab Matters Judith Reichmann will receive this year’s Paul Ehrlich and Ludwig Darmstaedter Prize for Young Researchers

2020

embl-announcementslab-matters

21 January 2020

Look at these curves!

Science & Technology The image shown here is a 3D-rendering created by Julian Hennies from the Schwab team.

2020

picture-of-the-weekscience-technology

20 January 2020

Science in School #49 available

EMBL AnnouncementsLab Matters The latest issue of the free magazine, Science in School, is now available for teachers worldwide.

2020

embl-announcementslab-matters

15 January 2020

Bridging Excellence Fellowships

EMBL AnnouncementsLab Matters The call for applications for Bridging Excellence Fellowships is now open

2020

embl-announcementslab-matters

14 January 2020

Ring of fire

Science & Technology This image has been composed from thousands of individual super-resolution microscopy images. It was created by Markus Mund in the Ries Group.

2020

picture-of-the-weekscience-technology

7 January 2020

Skittles for science

Science & Technology What might also be an artistic representation of a scattered bowl of Skittles is actually a 3D reconstruction of a high-pressure frozen HeLa cell.

2020

picture-of-the-weekscience-technology

31 December 2019

Tumour takeover

Science & Technology Breast cancer is the second leading cause of cancer-related deaths in women. It is so deadly because tumours often return after successful cancer treatment. This recurrence is caused by individual dormant cancer cells remaining inside the breast. These cells can develop into active cancer cells…

2019

picture-of-the-weekscience-technology

24 December 2019

Launching proteins

Science & Technology What looks like a photo-series of an explosive eruption are actually uptaking proteins, captured by Markus Mund from the Ries Group at EMBL Heidelberg. The images were made in an attempt to learn how the different proteins that take up molecules into the cells via endocytosis – the cellular…

2019

picture-of-the-weekscience-technology

19 December 2019 Before a biological sample reaches the beamline, a lot of work is put into its preparation. Scientists can use the wide range of services and resources at EMBL to prepare their biological samples for structural studies at the X-ray beamlines in Grenoble and Hamburg. Photo: Marietta Schupp/EMBL

Empowering European structural biology

EMBL AnnouncementsLab Matters EU funding for iNEXT-Discovery consortium unlocks key technologies for structural biology

2019

embl-announcementslab-matters

17 December 2019

Building Euro-BioImaging

Lab Matters EMBL’s Jan Ellenberg reflects on the process of forming a European research infrastructure

2019

lab-matters

17 December 2019

Reshaping our DNA

Science & Technology DNA is present in each cell of our body. If all the DNA from one human cell was removed and aligned in a single strand, it would in theory add up to a total length of about two metres. In order to fit into the nucleus of a cell, DNA has to be compressed by […]

2019

picture-of-the-weekscience-technology

13 December 2019

Graduation Ceremony 2019

Lab Matters Forty-seven PhD students from all of EMBL’s six sites were celebrated during EMBL’s 2019 Graduation Ceremony on Friday 13 December

2019

lab-matters

10 December 2019

Birth of two HeLa stars

Science & Technology This picture of the week, taken by Arina Rybina in the Ellenberg group at EMBL Heidelberg, shows a high-resolution 3D microscopy image of living human cells: HeLa cells. In this fascinating fluorescing microspace, two newly formed daughter nuclei are captured to study the assembly of nuclear pore…

2019

picture-of-the-weekscience-technology

9 December 2019

New chair of EMBL Council

EMBL AnnouncementsLab Matters Professor Eiríkur Steingrímsson will commence his initial one-year term as Chair of EMBL Council on 1 January 2020.

2019

embl-announcementslab-matters

3 December 2019 Black and blue hexagon shapes with some yellow and red hot spots

Skin mosaic

Science & Technology This beautiful mosaic of mostly hexagonal cells is the outer skin layer of a zebrafish larva as seen under a microscope. Each skin cell exhibits a unique pattern of actin ridges. Actin is a family of globular multifunctional proteins found in almost all eukaryotic cells. Actin forms microfilaments,…

2019

picture-of-the-weekscience-technology

29 November 2019 Choanocyte chamber of sponge, with neuroid cell

Neural pathways

Science & Technology Exploring the diverse routes by which EMBL scientists are driving forward neurobiology

2019

sciencescience-technology

26 November 2019

EMBL makes insulin visible

Science & Technology The hormone insulin helps to remove sugar from the blood after a meal. This is important, as in the long term high blood sugar levels damage our bodies. Diabetes of type 1 or type 2 is a direct consequence of a failure to produce sufficient insulin or to release it from the cells in which […]

2019

picture-of-the-weekscience-technology

25 November 2019 Phd student microscope

Careers after EMBL

Lab Matters For many students in the life sciences, finishing a PhD marks a professional crossroads

2019

lab-matters

19 November 2019

Formation of a brain

Science & Technology The brain is the most complex organ in the human body. Yet despite it being the organ that makes us conscious beings – and despite the fact that researchers have been studying it for generations – it’s still a constant source of surprise. To help lift the veil on some of its mystery, Lina…

2019

picture-of-the-weekscience-technology

18 November 2019

Fostering links with Montenegro

Connections Two recent events have expanded EMBL’s collaboration with one of its newest member states

2019

connectionsevents

15 November 2019 Fluorescence microscopy images of differentiated human hepatocytes

ATTRACT: funding innovation in imaging

EMBL AnnouncementsLab Matters EMBL is a collaborator in four of the projects funded in the first phase of ATTRACT.

2019

embl-announcementslab-matters

14 November 2019

New perspectives on nuclear pores

Science & Technology EMBL researchers have published two new studies involving the nuclear pore complex

2019

sciencescience-technology

5 November 2019

Edith’s inauguration

EMBL Announcements Edith Heard is inaugurated as EMBL Director General

2019

embl-announcementsevents

5 November 2019

A mix of sensations

Science & Technology Traditionally, we talk about having five senses: sight, hearing, taste, smell and touch. In reality, our bodies are capable of much more. Sitting right under our skin are a variety of sensory neurons, which are specialised in detecting light touch, pain, temperature, itch or the body’s position.…

2019

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30 October 2019

Fallingwater filled with mice

People & Perspectives Nadia Rosenthal describes how she built EMBL Rome’s mouse house

2019

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29 October 2019

Inside out, and grub becomes fly

Science & Technology The three bluish blobs shown in the top right corner of this image may not resemble the sphere of noodles that is the human brain, but they are still essential – at least for the fruit fly. This Picture of the Week shows the brain lobes of Drosophila. It’s an insect so tiny and so […]

2019

picture-of-the-weekscience-technology

23 October 2019 Steffen Lemke and Jakob Keck Genomics Core Facility

Engineering bacteria to fight diabetes

Science & Technology EMBL’s Genomics Core Facility supports students participating in the annual iGEM competition.

2019

sciencescience-technology

22 October 2019

A perfect model

Science & Technology Is it a fungus or a strange plant? Actually it’s the larval form of Platynereis – a group of marine ringed worms. Scientists have been using them in their studies for the past 70 years, and they are among the preferred lab organisms. They are easy to keep in the lab, and under temperature and…

2019

picture-of-the-weekscience-technology

18 October 2019

A tool to monitor tuberculosis

Science & Technology Funding awarded to EMBL-EBI for tuberculosis monitoring tool

2019

sciencescience-technology

15 October 2019

Bringing life science to you

Lab Matters EMBL not only produces excellent science and innovative technologies; it also shares its knowledge and experience with partners from around the world – and with the public. As well as offering teacher training in the European Learning Laboratory for the Life Sciences, science movie nights, and…

2019

lab-matterspicture-of-the-week

10 October 2019 Lars Steinmetz and Georgios Skiniotis

EMBL in the USA: future facing

People & Perspectives Scientists will discuss the challenges ahead for international science at the EMBL in the USA event.

2019

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9 October 2019

Science for everyone

Lab Matters During the Nacht der Forschung 2019, everyone was able to become a scientist for a day at EMBL

2019

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8 October 2019

The zebrafish earned its stripes

Science & Technology Despite missing the characteristic stripes one would expect from a zebra – or a zebrafish – the fractals in this Picture of the Week show a zebrafish; or at least some cells in a zebrafish embryo, a few hours after fertilisation. Zebrafish are not only popular aquarium fish, they are also an…

2019

picture-of-the-weekscience-technology

3 October 2019

EMBL and Tara: Barcelona

EMBL Announcements EMBL joins Tara in Barcelona to promote science and interdisciplinarity

2019

embl-announcementsevents

1 October 2019

The evolution of the eye

Science & Technology Model organisms are species that are studied extensively to understand particular biological phenomena and processes, with the expectation that discoveries made in the model organism will provide insight into the workings of other organisms. The small marine ringed worm Platynereis dumerilii gained…

2019

picture-of-the-weekscience-technology

26 September 2019 The Old Port of Marseille.

EMBL and Tara: Marseille

EMBL Announcements From 27–30 September, Tara will be docked in the port of Marseille, France’s second largest city.

2019

embl-announcementsevents

25 September 2019

A giant called dumpy

Science & Technology Fruit flies have something that we don’t have: they produce a protein called dumpy. This protein is the largest created by insects, and is comparable in size to the largest human protein – titin. While titin is vital for our muscle function, dumpy connects the soft cells of the insect’s…

2019

picture-of-the-weekscience-technology

17 September 2019

The end of a productive day

Lab Matters It’s evening and the Sun is setting over the mountains surrounding the city of Grenoble – home to one of EMBL’s six sites – bathing the mountaintops in fiery red light. The Picture of the Week, taken by Zuzanna Kaczmarska shows the lab she worked in after a long and busy day. Bottles…

2019

lab-matterspicture-of-the-week

12 September 2019 Tara stopover in Rome

EMBL and Tara: Rome

EMBL Announcements The next stop on Tara’s journey will be at the mouth of the Tiber

2019

embl-announcementsevents

10 September 2019

Tracking the beginning of life

Science & Technology All mammalian life starts with the fusion of egg and sperm, resulting in the creation of a single cell called a zygote. This develops into an embryo through a series of cell divisions, in which the number of cells doubles at each step. Todays’ Picture of the Week was taken by Manuel Eguren of the…

2019

picture-of-the-weekscience-technology

6 September 2019 EMBL-EBI celebrated its 25 anniversary on 1 September 2019. Credit: Spencer Phillips

25 years of EMBL-EBI

Lab Matters EMBL-EBI celebrated its 25 anniversary on 1 September 2019

2019

eventslab-matters

3 September 2019

A robust allrounder

Science & Technology This gorgeous image of a stained adult marine worm was created by former EMBL postdoc Hernando Martinez using structured microscopy. The worm itself was captured during plankton extraction off the coast of Sweden. There are over 10 000 species of these swimming worms, and they have adapted to every…

2019

picture-of-the-weekscience-technology

27 August 2019

Where science meets art

Lab Matters The most basic building blocks of life are the biological molecules in our cells. While these molecules are too small to see with most microscopes, they have incredibly complex and beautiful structures. Therefore, the Protein Data Bank in Europe (PDBe), The Art Society CANTAB and The Art Society…

2019

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26 August 2019

From rodents to roadsters

People & Perspectives Klaus Rajewsky recalls the pioneering spirit of EMBL Rome’s first years

2019

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20 August 2019

When life takes shape

Science & Technology Today’s picture of the week is not only a colourful one, it is also a snapshot of the vast number of shapes that the cells inside an animal body can adopt. How this variety comes about is investigated in the Leptin group at EMBL Heidelberg.  To understand the shapes of the cells in fruit fly…

2019

picture-of-the-weekscience-technology

13 August 2019

Have fun, be protected

People & Perspectives Working in a lab very often requires some kind of protection: gloves, safety goggles, lab coat, hearing protection. Sandra – now at BASF in Ludwigshafen – had fun getting ready for her work in the medicinal chemistry lab at EMBL! Here, she is about to grind potassium permanganate and copper…

2019

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12 August 2019

Obituary: Bernd-Uwe Jahn

EMBL Announcements Bernd-Uwe Jahn, former EMBL Administrative Director, Ministerialrat and Jurist has passed away

2019

alumniembl-announcements

6 August 2019

The muscles that regulate blood pressure

Science & Technology Low blood pressure (hypotension) or high blood pressure (hypertension) are risk factors for many diseases and affect more than 20% of the global population. How blood pressure is regulated is part of the research done in the Heppenstall group at EMBL Rome.  In today’s Picture of the…

2019

picture-of-the-weekscience-technology

2 August 2019 Eric Karsenti in Hamburg

We all come from the ocean

People & Perspectives Eric Karsenti's combined loves of biology and sailing set in motion the Tara Oceans expedition

2019

people-perspectivesscience

30 July 2019

Swiss day!

People & Perspectives The 1700 people working at EMBL’s six sites come from more than 80 different countries. Many of them haven’t come straight from their home country to one of the EMBL sites but have also lived in other countries in between. While all of them are proud to work at EMBL they are also proud of…

2019

people-perspectivespicture-of-the-week

29 July 2019 Dr Cristian D. Magnus

The challenge of diversity

People & Perspectives Dr Cristian D. Magnus discusses LGBTQ+ issues and diversity in science

2019

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26 July 2019 Lab day 2019

EMBL Lab Day 2019

Lab Matters EMBL Lab Day 2019 filled the ATC with art and games

2019

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23 July 2019 Manfred Lautenschläger

The donor’s code

People & Perspectives The main funder of the EMBL Lautenschläger Summer School reflects on codes of conduct around giving

2019

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23 July 2019

Muscle games

Science & Technology Every single moment of our life we use our muscles – most of the time without even thinking about it. Some muscles, like our heart, we cannot even control at all. How our brain communicates with our muscles is still not fully understood. The communication between our brain and our skeletal…

2019

picture-of-the-weekscience-technology

22 July 2019 Michael Zimmermann in the ATC.

Welcome: Michael Zimmermann

People & Perspectives Michael Zimmermann's group will investigate how gut microbes affect the body’s response to drugs.

2019

people-perspectivesscience

18 July 2019 Heatmap representing the stability of an integral membrane proteins

First results from CSSB

Science & Technology EMBL scientists collaborate to develop new protocol for screening membrane protein stability

2019

sciencescience-technology

16 July 2019

The birth of new cells – when two become four

Science & Technology This colourful picture, taken by EMBL postdoc Arina Rybina using a confocal fluorescence microscope, shows human cells in the process of cell division. Eventually, each mother cell brings into existence two identical daughter cells. To visualise the process by light microscopy, different cell…

2019

picture-of-the-weekscience-technology

15 July 2019 The pyramids represent chromatin domains in the wild-type situation. The reflection in the water below represents the rearrangements in the mutant fruit fly chromosomes. At first glance the (regulatory) landscapes look very similar, but there are lots of changes to the topology, and yet these have little impact on the nature of the landscape (gene expression). IMAGE: Beata Edyta Mierzwa in collaboration with EMBL.

Rearranging chromosomes

Science & Technology Does rearranging chromosomes affect their function? EMBL scientists reveal uncoupling of 3D chromatin organisation and gene expression.

2019

sciencescience-technology

12 July 2019 Suzanne Eaton, former EMBL staff scientist from 1993–2001. PHOTO: EMBL

In remembrance of Suzanne Eaton

EMBL Announcements The life science community is deeply saddened by the death of Suzanne Eaton

2019

alumniembl-announcements

11 July 2019 Structure of the Elongator complex

A tRNA modifier at work

Science & Technology Using cryo-EM, scientists have determined the structure of a large protein complex called Elongator.

2019

sciencescience-technology

10 July 2019 A word cloud displaying the most frequently used words in issue 93 of the EMBLetc. magazine

Programming: language

Science & Technology How computer processing of human language is harnessed by EMBL scientists

2019

sciencescience-technology

9 July 2019 A model of CRISPR/Cas9

Wielding the genetic scissors

Science & Technology What CRISPR may bring for the future of biology, and how it is used at EMBL

2019

sciencescience-technology

9 July 2019

Working with a view

Lab Matters EMBL has six sites in Europe and the newest is EMBL Barcelona. It opened in October 2017 and is still growing. Eventually, it will be home to eight research groups, all of them working to discover how tissues and organs function and develop. EMBL Barcelona is located in the Barcelona Biomedical…

2019

lab-matterspicture-of-the-week

5 July 2019 Picture of a fern gametophyte

Fun with fern photography

EMBL Announcements EMBL alumna Jennifer Deegan built a prize-winning system for photographing ferns

2019

alumniembl-announcements

5 July 2019 Alessandro Ori in the lab

Decoding ageing

People & Perspectives The naked mole-rat as a model organism in ageing research

2019

alumnipeople-perspectives

2 July 2019 BioImage Archive Logo

A new home for biological images

Science & Technology The BioImage Archive - EMBL-EBI's first dedicated imaging data resource

2019

sciencescience-technology

2 July 2019

Cell duplication

Science & Technology What looks like a pair of scary alien eyes is actually the final stage in the duplication of a cell. Cell duplication is preceded by a process called mitosis, in which the replicated chromosomes are separated into two new nuclei. Mitosis is the prerequisite for a cell to divide into two identical…

2019

picture-of-the-weekscience-technology

1 July 2019 The dynamic process of cell division.

Drawing knowledge

People & Perspectives A conversation about art-science collaborations and the importance of drawing in biology.

2019

people-perspectivesscience

28 June 2019 EIPOD4 logo banner showing the 4 available tracks, research, industrial, clinical and academic.

EIPOD4: 2019 applications are open

EMBL AnnouncementsLab Matters EIPOD4 will prepare researchers for the increasing interdisciplinarity of scientific career paths

2019

embl-announcementslab-matters

25 June 2019

A colourful day at EMBL-EBI

Lab Matters EMBL is an intergovernmental organisation, currently supported by 26 member states, one prospect and two associate member states. There are more than 1700 people working at EMBL, who come from more than 80 countries, creating a multicultural environment. EMBL also operates from six sites in Europe:…

2019

lab-matterspicture-of-the-week

19 June 2019 The ELLS team

Building engagement

Lab Matters The team at ELLS use Lego to teach children the fundamentals of DNA.

2019

lab-matters

18 June 2019

A no-brainer

Lab Matters Have you ever wondered what reflex testing is about? Why does your doctor tap the space below your knee with a hammer to see if your leg kicks forward? At the centre of this involuntary reaction is the muscle spindle, of which you can see a close-up in today’s Picture of the Week. Muscle spindles…

2019

lab-matterspicture-of-the-week

17 June 2019 A photo of the Hamburg harbour at dusk

EMBL and Tara: Hamburg

EMBL Announcements EMBL Hamburg and Tara raise awareness of the risks of microplastic pollution and global infection

2019

embl-announcementsevents

13 June 2019 Photo of James Sharpe

James Sharpe elected EMBO Member

Lab MattersPeople & Perspectives The head of EMBL’s Barcelona site joins a prestigious group of more than 1800 scientists worldwide

2019

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11 June 2019 Lithuanian flag

Sveika, Lietuva!

EMBL AnnouncementsLab Matters Lithuania becomes EMBL’s 27th member state

2019

embl-announcementslab-matters

11 June 2019

Rainbow lab

Lab Matters Laboratories all over the world are often chaotic, a bit messy and look grey and unwelcoming. Not so in this lab, pictured by EMBL staff member Emily Savage. The differently coloured fluids, arranged in a row, bring vivid colours into the more subdued environment of the lab. The picture was taken…

2019

lab-matterspicture-of-the-week

6 June 2019 Photo of University of Cambridge professor Tim Lewens

Editing the ethical code

Lab Matters Professor Tim Lewens challenges the human genome’s unique place in bioethics

2019

eventslab-matters

4 June 2019

Colourful yeast

Lab Matters Most of us love brewer’s yeast, or at least the food that it’s helped us to produce since ancient times. Without Saccharomyces cerevisiae (its Latin name) we couldn’t enjoy wine, beer or most types of bread. Besides its role in food production, S. cerevisiae is also an important model…

2019

lab-matterspicture-of-the-week

31 May 2019 EMBL scientists in a bar for the event Pint of Science

A thirst for science

Lab Matters EMBL got together with the global science festival Pint of Science to explain and celebrate science.

2019

eventslab-matters

28 May 2019

A fiery end to a productive day

Lab Matters EMBL’s sites provide spectacular views, such as this fiery sunset at the Wellcome Genome Campus in Hinxton. The campus, in the heart of the Cambridgeshire countryside, is home to several institutes and organisations working on genomics and computational biology. Among them is EMBL’s European…

2019

lab-matterspicture-of-the-week

21 May 2019

From fruit flies to cancer treatment

Science & Technology This image – resembling a network of rivers and canals – actually shows the tracheal tip cell of a fruit fly. Fruit flies are heavily used in research and they are a common model organism in developmental biology. Researchers at EMBL use the larvae of fruit flies to study tracheal cell…

2019

picture-of-the-weekscience-technology

14 May 2019

Walking on DNA

Science & Technology EMBL is a world-leading organisation for life science research. Its scientists work in diverse research fields spanning the whole of molecular biology. While the molecules the researchers are working on are often microscopic and impossible to see with the naked eye, one research topic clearly…

2019

picture-of-the-weekscience-technology

7 May 2019

EMBL sees it all

Lab Matters The hexagons visible in this Picture of the Week are the eyes of an ordinary housefly, visualised with a scanning electron microscope. Former staff member Anna Steyer, who captured this brilliant image, has coloured seven of the receptor areas of the eye to create a stylised version…

2019

lab-matterspicture-of-the-week

29 April 2019 This illustration, based on real data shows the heart of a Japanese rice fish. The green and blue laser beams demonstrate how the newly developed 3D imaging microscope is scanning the heart.

New 3D microscope

Science & Technology A newly developed 3D microscope visualises fast biological processes better than ever.

2019

sciencescience-technology

25 April 2019 The proteotype of an individual is substantially affected by both its sex and its diet.

Sex and diet affect proteotype

Science & Technology EMBL scientists have discovered that the proteome is substantially affected by both sex and diet

2019

sciencescience-technology

18 April 2019

Edith and Iain in conversation

Lab Matters The current and previous Directors General discuss what it means to lead an organisation like EMBL

2019

lab-matters

11 April 2019 group photo of Janna Saarela, Mark Daly, EMBL Director General Edith Heard, former EMBL Director General Iain Mattaj, Poul Nissen, Oliver Billker

Partners in the north

Lab Matters The Nordic EMBL Partnership directors discuss the value of collaborating across borders

2019

lab-matters

8 April 2019 New head of Office of Resource Development at EMBL, Joana WItkowski, stands inside the ATC building at EMBL Heidelberg

Welcome: Joana Witkowski

Lab Matters New head of ORD will build and expand the partnerships that help EMBL achieve its ambitions

2019

lab-matters

5 April 2019 IMAGE: EMBL

The Crick and EMBL join forces

Lab Matters The Francis Crick Institute and EMBL have agreed to work together to strengthen European science

2019

lab-matters

26 March 2019 BRAINCITY is an independent unit at the Nencki Institute of Experimental Biology in Warsaw, Poland. PHOTO: Michalj2 (CC BY-SA 4.0)

EMBL partners with BRAINCITY

ConnectionsLab Matters EMBL begins partnership with Polish centre of excellence for neural plasticity and brain disorders

2019

connectionslab-matters

18 March 2019 A smiling Santiago Rompani, new group leader at EMBL Rome, stands in front of a vine covered wall

Welcome: Santiago Rompani

People & Perspectives New EMBL group leader explores what neurobiology can teach us about what it means to be human

2019

people-perspectivesscience

14 March 2019 Guest looking at a panel at the REMIX exhibition produced for the European Researchers’ Night 2018

Advancing science and new perspectives

People & Perspectives On 20 February, over 250 local supporters and friends met Edith Heard to celebrate a successful year

2019

eventspeople-perspectives

11 March 2019 A visualisation of a membraneless organelle in the green-yellow style of the data presented in the Nature Communications paper

ATP affects proteome-wide solubility

Science & Technology Scientists develop technology to measure how ATP concentration affects protein solubility in cells

2019

sciencescience-technology

8 March 2019 Sagar Bhogaraju portrait photo

Welcome: Sagar Bhogaraju

Science & Technology New group leader at EMBL Grenoble is investigating the cellular role of melanoma antigens

2019

sciencescience-technology

21 February 2019 Tanmay Bharat and Patrick Baeuerle, winners of the EMBL's 2019 alumni awards

2019 alumni awards

People & Perspectives Scientists honoured for contributions in cancer immunotherapy and structural biology

2019

alumnipeople-perspectives

6 February 2019 Poland becomes EMBL’s 26th member state

Witamy, Polsko!

ConnectionsLab Matters On 5 February 2019, EMBL welcomed Poland as its 26th member state

2019

connectionslab-matters

18 December 2018

Design thinking

Lab MattersPeople & Perspectives EMBL’s Design Team Lead on translating scientific discoveries into visual designs

2018

lab-matterspeople-perspectives

17 December 2018 Mouse skin samples of the rare genetic skin disease amyloidosis, before light treatment (left) and after treatment (right). The arrows indicate aggregates of debris, which cause the skin to become rough and uncomfortable. Upon treatment these aggregates are reduced, allowing the skin to heal. IMAGES: Paul Heppenstall and Linda Nocchi / EMBL

Using light to stop itch

Science & Technology EMBL researchers have found a way to stop itch with light in mice

2018

sciencescience-technology

17 December 2018 Stephan Schiffels is a group leader at the Max Planck Institute for the Science of Human History in Jena, Germany. PHOTO: MPI-SHH

Reconstructing the human past

People & Perspectives What genetics can tell us about the structure of ancient human populations

2018

eventspeople-perspectives

10 December 2018 artistic impression of the double helix structure of DNA

Model to predict prostate cancer progress

Science & Technology Cancer researchers have developed a computer model to predict the course of disease for prostate cancer

2018

sciencescience-technology

5 December 2018 Silke Schumacher, EMBL Director of International Relations, and Tamás Bíró, HCEMM Director General, at the signing of the Partnership Agreement. PHOTO: NRDI Office, Hungary

New EMBL Partnership in Hungary

ConnectionsLab Matters EMBL partners with the Hungarian Centre of Excellence for Molecular Medicine

2018

connectionslab-matters

28 November 2018 EIPOD postdocs work together as part of the Corporate Summer School.

Science in industry

Lab Matters EMBL postdocs discover industry-led research opportunities at the Corporate Summer School

2018

eventslab-matters

26 November 2018 Sarah Butcher EMBL-EBI Technical Team Leader

Welcome: Sarah Butcher

Lab Matters Building bridges between scientists and software developers

2018

lab-matters

22 November 2018 Portrait of Nina Kathe

Ambition and talent

Lab Matters Nina Kathe, Winner of the EU Contest for Young Scientists visits EMBL

2018

eventslab-matters

15 November 2018 Top view picture of modified and natural invagination in a tissue

Controlling organ growth with light

Science & Technology The De Renzis group investigated invagination, the first step of organ development in embryos.

2018

sciencescience-technology

2 November 2018 RNA-binding protein

Catching up on protein dynamics

Science & Technology The Hentze Lab enhanced a RNA-interactome capture technique to pave the way towards medical progress

2018

sciencescience-technology

31 October 2018 Internal anatomy of the marine worm’s head.

A worm’s sense of the world

Science & Technology EMBL researchers discover that four organs in a marine worm’s head can sense different chemicals

2018

sciencescience-technology

30 October 2018 Sanofi logo on blue background

Sanofi joins Open Targets

ConnectionsLab Matters Pharmaceutical company Sanofi strengthens drug targets discovery collaboration Open Targets

2018

connectionslab-matters

29 October 2018 James Sharpe, the head of EMBL Barcelona, speaks at the Inauguration Symposium.

¡Hola, Barcelona!

Connections EMBL Barcelona invites locals to celebrate its Inauguration Symposium

2018

connectionsevents

22 October 2018 An 88% complete model of human hemoglobin (PDB id 5ni1) built de novo by ARP/wARP into a 3.2 Å cryo-EM map. IMAGE: Victor Lamzin/EMBL

ARP/wARP 8.0 released

Lab MattersScience & Technology Researchers at EMBL Hamburg have released the next generation of their ARP/wARP software

2018

lab-mattersscience-technology

19 October 2018 A group of young students in front of the EMBL site in Hamburg.

Guiding young scientists

Connections 17 young scientists experienced hands-on training at EMBL Hamburg.

2018

connectionsevents

9 October 2018 Wendy Bickmore. PHOTO: Massimo Del Prete

EMBL in the UK: Wendy Bickmore

People & Perspectives Meet Wendy Bickmore, Director of the MRC Human Genetics Unit, who spoke at the EMBL in the UK event

2018

alumnipeople-perspectives

8 October 2018 Gareth Griffiths and Rein Aasland at the CASE awards.

Excellent alumni

Connections EMBL alumni Gareth Griffiths and Rein Aasland receive the 2018 “Volunteer of the Year” award

2018

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4 October 2018 Lola Ledesma. PHOTO: Jose Antonio Pérez/CBMSO

EMBL in Spain: Lola Ledesma

Connections EMBL alumni and researchers working throughout Spain met in Madrid

2018

alumniconnections

17 September 2018 The retromer complex

Solving the structure of retromer

Science & Technology Retromer’s 3D structure improves understanding of cellular sorting and packaging

2018

sciencescience-technology

29 August 2018 During cell division, cohesin directly engages DNA (purple) and holds the replicated chromosome together. IMAGE: Nasser Rusan/National Institutes of Health

Cohesin: a glue for DNA

Science & Technology EMBL scientists discover how a component of the cohesin ring binds DNA

2018

sciencescience-technology

27 August 2018 Robbert Dijkgraaf, director of the Institute for Advanced Study in Princeton, US

The usefulness of useless knowledge

People & Perspectives Theoretical physicist Robbert Dijkgraaf discusses the importance of curiosity-based research

2018

eventspeople-perspectives

22 August 2018

Welcome: Jim Swoger

People & Perspectives New head of the Mesoscopic Imaging Facility at EMBL Barcelona will help scientists visualise nature

2018

people-perspectivesscience

14 August 2018 EMBL lab day 2018 - Key visual for Iain Mattaj's staff farewell event

Celebrating science

Lab Matters The EMBL community, past and present, gather for special events around Lab Day 2018

2018

eventslab-matters

7 August 2018 Group picture of the students and coordinators of the second edition of ‘Summer in Science’ at EMBL Rome. PHOTO: Berta Carreño/EMBL

Summer in Science 2018

Lab Matters EMBL Rome opens its labs for students to get their first real taste of science

2018

eventslab-matters

3 August 2018 Optical section of a ‘gastruloid’ – an embryonic organoid made from mouse embryonic stem cells and stained for E-Cadherin (red), marking cell outlines and nuclei (blue). IMAGE: Vikas Trivedi/EMBL

Welcome: Vikas Trivedi

People & Perspectives An engineer’s approach to understanding morphogenesis

2018

people-perspectivesscience

2 August 2018 Humans of EMBL: Outreach

Humans of EMBL: Outreach

Lab MattersPeople & Perspectives Discover how EMBLers across all sites share their passion for science

2018

lab-matterspeople-perspectives

26 July 2018

The proteins behind hungry cells

Science & Technology EMBL researchers visualise the proteins needed to capture molecules and bring them into a cell

2018

sciencescience-technology

26 July 2018 Acrylic painting of couple made of proteins

Art meets structural biology

Lab Matters The Protein Data Bank in Europe celebrates its schools art project with its largest exhibition yet

2018

lab-mattersscience

9 July 2018 Miki Ebisuya at EMBL Barcelona

Welcome: Miki Ebisuya

People & Perspectives New group leader at EMBL Barcelona creates artificial biological systems to study animal development

2018

people-perspectivesscience

27 June 2018 PHOTO: Photolab/EMBL

Powering up

People & Perspectives Alumni share how joining EMBL’s IT team was a career upgrade

2018

alumnipeople-perspectives

20 June 2018 EMBL scientists extend Turing’s theory to help understand how biological patterns are created. IMAGE - Xavier Diego, EMBL

New insights into Turing patterns

Science & Technology EMBL scientists extend Turing’s theory to help understand how biological patterns are created

2018

sciencescience-technology

19 June 2018 Kristina Havas-Cavalletti

EMBL in Italy: Kristina Havas-Cavalletti

People & Perspectives More than 80 attendees gathered at the EMBL in Italy event at the FIRC Institute of Molecular Oncology (IFOM) in Milan

2018

alumnipeople-perspectives

8 June 2018 A stylised birds eye view of the EMBL Heidelberg Campus in green, black and white.

EMBL in six objects

Lab Matters A history of EMBL in six objects from the EMBL Archive

2018

lab-matters

4 June 2018 New EMBL group leader Simone Köhler.

Welcome: Simone Köhler

People & Perspectives Which of our genes will be passed on to our children? Simone Köhler wants to find out

2018

people-perspectivesscience

1 June 2018 EMBL researchers and collaborators enjoy their EMBL pints.

A pint of EMBL science

Lab Matters EMBL and Pint of Science join forces to entertain and educate

2018

eventslab-matters

24 May 2018 Daniel Elias Martin Herranz EMBL-EBI

PhD goals: why not start a company?

Lab MattersPeople & Perspectives EMBL-EBI PhD student launches start-up focusing on epigenetics and wellbeing

2018

lab-matterspeople-perspectives

23 May 2018 As a cell prepares to divide, the chromosomes (shown here in pink) condense, becoming more tightly coiled and easier to observe under the microscope. The faint structure in the centre is a cell nucleus in which the chromosomes are in their usual decondensed state.

Exploring genetic variation

Science & Technology EMBL group leader Jan Korbel reflects on his scientific origins and current research

2018

sciencescience-technology

14 May 2018 EMBL alumna Elisa Izaurralde.

Obituary: Elisa Izaurralde

People & Perspectives Elisa Izaurralde, EMBL alumna, has passed away

2018

alumnipeople-perspectives

11 May 2018 Iain Mattaj has been elected as a foreign associate of the National Academy of Sciences (NAS) of the United States of America.

Iain Mattaj elected NAS foreign associate

EMBL AnnouncementsLab Matters EMBL’s Director General has been elected to the National Academy of Sciences of the United States

2018

embl-announcementslab-matters

9 May 2018 Benito-Gutiérrez searching for cephalochordates on board the dhoni boat

Ocean origins

Lab MattersPeople & Perspectives EMBL alumna, Èlia Benito-Gutiérrez, on how her research and career evolved after searching the seas

2018

lab-matterspeople-perspectives

4 May 2018 Celgene logo on white background

Celgene joins Open Targets

ConnectionsLab Matters New partner strengthens drug discovery collaboration

2018

connectionslab-matters

24 April 2018

Managing chronic pain with light

Science & Technology Scientists at EMBL Rome develop new method that uses light to manage neuropathic pain in mice

2018

sciencescience-technology

23 April 2018

International science: Sanja Damjanović

ConnectionsLab Matters Montenegro’s Minister of Science discusses the importance of international collaboration in research

2018

connectionslab-matters

20 April 2018 Anna Kreshuk

Welcome: Anna Kreshuk

People & Perspectives New Heidelberg group leader creates tools to help biologists work faster and better

2018

people-perspectivesscience

28 March 2018 Virginie Uhlmann on EPFL campus

Welcome: Virginie Uhlmann

People & Perspectives New EMBL-EBI Group Leader will make sense of bioimaging data

2018

people-perspectivesscience

22 March 2018

LifeTime – a visionary proposal for an EU Flagship

ConnectionsLab Matters Following the completion of the Human Genome Project  in 2001, scientists and the media described the genome as “the book of life”, holding the answers to the way genes are linked to disease. Yet, seventeen years later, we are still deciphering how cells interpret this book. Since…

2018

connectionslab-matters

21 March 2018 Maria Garcia Alai at the Sample Preparation and Characterisation Facility at EMBL Hamburg. PHOTO: EMBL/Joanna Pieprzyk

Welcome: Maria Garcia Alai

People & Perspectives The new head of facility at EMBL Hamburg will help users solve protein puzzles

2018

people-perspectivesscience

20 March 2018 A heatmap graph displaying high (red) or low (blue) levels of gene expressions in different cells.

From blood vessels to blood stem cells

Science & Technology EMBL scientists discover how blood vessel cells become blood stem cells during embryonic development

2018

sciencescience-technology

19 March 2018 Commonly used drugs affect our gut bacteria.

Commonly used drugs affect our gut bacteria

Science & Technology One in four drugs with human targets inhibit the growth of bacteria in the human gut, and may promote antibiotic resistance, EMBL researchers report in Nature

2018

sciencescience-technology

15 March 2018 How drugs affect the life and death of proteins. IMAGE: Cell

How drugs affect the life and death of proteins

Science & Technology Scientists at EMBL and Cellzome develop technology to monitor the effects of drug treatments on protein degradation and synthesis

2018

sciencescience-technology

14 March 2018

DNA replication stress in cancer

Science & Technology Thanos Halazonetis discusses the EMBO/EMBL Symposium: DNA Replication: From Basic Biology to Disease

2018

eventsscience-technology

12 March 2018 Robert Prevedel talks about EMBL and microscopy at the Internationale Gesamtschule Heidelberg. PHOTO: EMBL/Hugo Neves

Science in a suitcase

Lab Matters School students build fluorescence microscopes designed by members of the Prevedel group and ELLS

2018

eventslab-matters

8 March 2018 Netrin-1 bound to Draxin

Axon guidance and bundling are linked

Science & Technology EMBL scientists discover how two guidance cues work together when neurons project axons across the midline

2018

sciencescience-technology

7 March 2018 EMBL spinoff Velabs Therapeutics to help antibody discovery. IMAGE: Velabs Therapeutics

EMBL spinoff to help antibody discovery

Lab MattersScience & Technology New EMBL spinoff company Velabs Therapeutics aims to speed up discovery of therapeutic antibodies

2018

lab-mattersscience-technology

5 March 2018 Maria Leptin, EMBO Director and EMBL group leader

A chance to make scientists’ voices heard

Lab MattersPeople & Perspectives Maria Leptin reflects on how to create a research environment that serves the needs of the community

2018

lab-matterspeople-perspectives

28 February 2018

Origins at EMBL

Science & Technology Join us in our new editorial theme as we ask how everything began

2018

sciencescience-technology

23 February 2018 Meet some of the Humans of EMBL

Humans of EMBL: Past lives

Lab MattersPeople & Perspectives Discover the past lives and journeys that brought people to EMBL

2018

lab-matterspeople-perspectives

16 February 2018 New EMBL group leader Sara Cuylen-Häring will explore biophysical properties of chromosomes and other cellular assemblies.

Welcome: Sara Cuylen-Häring

People & Perspectives New EMBL group leader explores biophysical properties of chromosomes and other cellular assemblies

2018

people-perspectivesscience

15 February 2018 School visit on the International Day of Women and Girls in Science

Women in Science Day: school event

Lab Matters EMBL Barcelona organises first school activity to coincide with the International Day of Women in Science

2018

eventslab-matters

15 February 2018 Architecture dependent turnover of the nuclear pore subunits. Top row shows the nuclear pore subunits seen from top, bottom row shows subunits of the nuclear pore cut in half.

Life and death of proteins

Science & Technology EMBL scientists create a turnover catalogue of almost 10.000 proteins from primary cells

2018

sciencescience-technology

12 February 2018 Charles Darwin portrait gravure - Darwin’s studies of orchids firmly established the idea that many types of flowers are pollinated by insects. PHOTO: iStock

On the orchids of Darwin

Science & Technology How Darwin’s work revealed the intimate relationship between orchids and insects

2018

sciencescience-technology

9 February 2018 Arnaud Krebs, EMBL’s new group leader studies how gene expression is controlled

Welcome: Arnaud Krebs

People & Perspectives EMBL’s new group leader studies how gene expression is controlled

2018

people-perspectivesscience

29 January 2018 General view of the ID23-2 sample environment showing the MD3-Up diffractometer and FlexHCD sample changer. PHOTO: EMBL/J. Sinoir

Beamline ID23-2 tools up for ESRF upgrade

Lab MattersScience & Technology EMBL instrumentation teams adapting tech to run biological experiments on the synchrotron after its upgrade

2018

lab-mattersscience-technology

15 January 2018 This mouse ovary and these immature eggs (in blue), can be used to study patterns of DNA methylation that affect only females.

Welcome: Matthieu Boulard

People & Perspectives New EMBL group leader investigates the mystery of heritable gene silencing

2018

people-perspectivesscience

8 January 2018 A photo of new EMBL Heidelberg group leader Aissam Ikmi.

Welcome: Aissam Ikmi

People & Perspectives New group leader studies sea anemones to investigate why some animals regenerate better than others

2018

people-perspectivesscience

4 January 2018 Schematic reconstruction of the Robo1 structure. IMAGE: Andrew McCarthy / Structure

One way crossing across the midline

Science & Technology EMBL researchers solve a decades-long debate on a key process for brain and embryo-development

2018

sciencescience-technology

22 December 2017 John Kendrew, c. 1978, visits the site of the EMBL main laboratory in Heidelberg. Photo taken by Frieda Glockner (EMBL Archive / DE 2324 P-GLO)

Molecular biology as a force for peace

Lab MattersPeople & Perspectives Historian Soraya de Chadarevian explores how EMBL’s first Director General shaped molecular biology

2017

lab-matterspeople-perspectives

21 December 2017

Your favourite reads of 2017

Lab Matters A look back at some of the most read stories on EMBL’s news website this year

2017

lab-matters

20 December 2017 The most curious genomes in Ensebl. Credit: Spencer Phillips/EMBL-EBI

Curious genomes

Science & Technology What are the strangest genomes in EMBL-EBI's Ensembl?

2017

sciencescience-technology

20 December 2017 In this representation of influenza polymerase, a molecule (white) that strongly inhibits the enzyme’s activity is shown bound to the region of the enzyme (red) that usually binds the cap section of mRNA. IMAGE: EMBL/Cusack Group

Futures: Unravelling influenza

Science & Technology ERC grantee Stephen Cusack shares his vision for the next ten years

2017

sciencescience-technology

14 December 2017 Illustration of complicated datasets

The future of training

Lab Matters EMBL experts outline the trends shaping scientific training in the coming years

2017

eventslab-matters

14 December 2017 Philipp Keller’s work imaged the early development of a zebrafish embryo using light sheet microscopy

A physical revolution

People & Perspectives EMBL physicist-turned-biologist alumni win 2017 Kendrew and Phillipson awards

2017

alumnipeople-perspectives

5 December 2017 Lab manager Anna Cyrklaff takes a tray of fly specimens to be transferred into new vials

Behind the scenes in the Fly Room

Lab MattersPeople & Perspectives Curious about what goes on in EMBL’s Fly Room? Prepare to be a fly on the wall

2017

lab-matterspeople-perspectives

4 December 2017 A photo of Eva Kowalinski

Welcome: Eva Kowalinski

People & Perspectives New group leader based in Grenoble aims to unveil the mechanisms of RNA editing

2017

people-perspectivesscience

30 November 2017 Portrait of Edith Heard

Edith Heard awarded Grand Prix Inserm 2017

EMBL AnnouncementsLab Matters EMBL Director General elect, Edith Heard, awarded 2017’s Grand Prix Inserm for her work in epigenetics

2017

embl-announcementslab-matters

29 November 2017 Collage of photos of some humans of EMBL discussed in this article

Humans of EMBL: Curiosity

Lab Matters EMBLers across all sites share how their curiosity about the world shapes their everyday life

2017

lab-matters

24 November 2017 Cryo-electron tomograms of intact cells reveal molecular landscapes.

Welcome: Julia Mahamid

People & Perspectives The Mahamid group studies meso-scale molecular assemblies in intact cells and model organisms at molecular resolution

2017

people-perspectivesscience

23 November 2017 Floating approximately 400 km above the Earth, the International Space Station provides a platform for scientific research in space.

Science in space

People & Perspectives EMBL alumna Sigrid Reinsch trained as a cell biologist – now she helps run experiments in space

2017

alumnipeople-perspectives

21 November 2017 Fotis was EMBL's third Director-General. PHOTO: EMBL

Obituary: Fotis Kafatos

People & Perspectives Former EMBL Director General Fotis Kafatos passes away

2017

alumnipeople-perspectives

20 November 2017

#EMBLcurious

Lab MattersPeople & Perspectives Six curious questions and the EMBL community's answers. Check back each week for the next question

2017

lab-matterspeople-perspectives

16 November 2017 Photo of Jacques Dubochet giving a talk

A curious case of serendipity

People & Perspectives Jacques Dubochet, Nobel laureate and former EMBL group leader, reflects on a key aha moment

2017

alumnipeople-perspectives

13 November 2017

Research highlights

Science & Technology A summary of recent research highlights from EMBL

2017

sciencescience-technology

25 October 2017 A hand lifting a curtain, revealing a blue eye behind the curtain

What is EMBL curious about?

Science & Technology Find out how curiosity is driving some of the work we do here at EMBL

2017

sciencescience-technology

25 October 2017

To laugh, and then think

Science & Technology Meet Ig Nobel emcee Marc Abrahams, an EMBL Science and Society speaker in December

2017

eventsscience-technology

25 October 2017 Midnight at Aurora Basin North in Antarctica. PHOTO: Simon Sheldon

Science from ice

People & Perspectives Working on scientific instruments has taken EMBL alumnus Simon Sheldon to the ends of the Earth

2017

alumnipeople-perspectives

19 October 2017 Margret Suckale kicking off the Women’s Night in the rooftop lounge at EMBL. credits: Marietta Schupp/EMBL

EMBL Women’s Night in Heidelberg

Lab Matters Women from academia, industry and politics met at EMBL to fuel career growth and opportunities

2017

eventslab-matters

3 October 2017 The structure of the nuclear pore complex obtained by integrative modelling

Welcome: Jan Kosinski

People & Perspectives EMBL’s new group leader based in Hamburg aims to create models of infection cycles

2017

people-perspectivesscience

29 September 2017 Photo of Andrew Leach, Head of Chemical Biology data services at EMBL-EBI

Welcome, Andrew Leach

People & Perspectives Q&A with EMBL-EBI's Head of Chemical Biology data services

2017

people-perspectivesscience

22 September 2017 Aerial view of EMBL-EBI Training Symposium 2017

Ten years of training at EMBL-EBI

Lab Matters International experts gather at EMBL-EBI to reflect on the future of bioinformatics training

2017

eventslab-matters

21 September 2017

Fish on fire

Science & Technology New study by Paola Kuri and Maria Leptin shows how inflammation happens in zebrafish in real time

2017

sciencescience-technology

7 September 2017 Thomas Schwarzl and Ina Huppertz in cool sunglasses at the Science Movie Night

Science + X: The science behind the Matrix movie

Lab MattersPeople & PerspectivesScience & Technology EMBL researchers separated facts from fiction at a Friends of EMBL Science Movie Night

2017

lab-matterspeople-perspectivesscience-technology

25 August 2017

Opinion: Archives for Science

Lab MattersPeople & Perspectives Biologists Sydney Brenner and Richard J. Roberts addressed the importance of scientific archives

2017

lab-matterspeople-perspectives

11 August 2017

Welcome: Justin Crocker

People & Perspectives Meet Justin Crocker, EMBL’s new group leader in gene regulation during evolution and development

2017

people-perspectivesscience

9 August 2017 Photo of Evangelia Petsalaki by Mary Todd Bergman, EMBL-EBI

Welcome: Evangelia Petsalaki

People & Perspectives A new group at EMBL-EBI aims to decipher cell signalling networks

2017

people-perspectivesscience

1 August 2017 EMBL-EBI group leader Zamin Iqbal

Welcome: Zamin Iqbal

People & Perspectives The Iqbal research group hopes to build a 'Google of bacteria' to help better interpret the genome

2017

people-perspectivesscience

24 July 2017 Map of Latin America

Bioinformatics in Latin America

ConnectionsLab Matters EMBL-EBI supports bioinformatics training and capacity in Latin America

2017

connectionslab-matters

11 July 2017

New name for EMBL’s site in Italy

EMBL AnnouncementsLab Matters EMBL’s unit in Italy changes name to better reflect new research focuses and highlight its location

2017

embl-announcementslab-matters

6 July 2017

CSSB opens its doors

ConnectionsLab Matters On 29 June, at a ceremony in front of 700 guests, the Centre for Structural Systems Biology (CSSB) in Hamburg, was officially opened. At the event on the Deutsches Elektronen-Synchrotron (DESY) Campus in Hamburg, Helmut Dosch, Chairman of the DESY Board of Directors, presented Head of EMBL Hamburg…

2017

connectionslab-matters

26 June 2017 Is the sex of animals misdirecting research?

The sexual dimorphism dilemma

Science & Technology IMPC explains how much the sex of animals is misdirecting research results

2017

sciencescience-technology

26 June 2017 Mouse disease models

Mouse genes could help decipher disease

Science & Technology EMBL-EBI and IMPC characterised over 3000 mouse genes, revealing new gene associations with disease

2017

sciencescience-technology

15 June 2017 Revathi Nathaniel, UX expert at EMBL-EBI.

UX toolkit aids industry R&D

Science & Technology Exploring the potential of user experience for life sciences through industry workshops

2017

eventsscience-technology

14 June 2017 Image Data Resource

Open imaging data for biology

Science & Technology The Image Data Resource - prototype of the first open repository linking imaging and molecular data

2017

sciencescience-technology

13 June 2017

Senses: Fathoming fear

Science & Technology EMBL’s Cornelius Gross wants to understand fear responses and the brain circuitry that governs them

2017

sciencescience-technology

9 June 2017

Mapping gene expression, cell by cell

Science & Technology EMBL researchers complete a molecular atlas showing gene expression in all cells in an entire animal

2017

sciencescience-technology

6 June 2017

Senses: Silencing noise

Science & Technology Two EMBL researchers are exploring new ways to filter out noise and get to the data they need

2017

sciencescience-technology

1 June 2017 Human Cell Atlas logo and motif

Human Cell Atlas data platform kicks off

Lab MattersScience & Technology EMBL-EBI, the Broad and UCSC Genomics Institute to build Data Coordination Platform with CZI support

2017

lab-mattersscience-technology

31 May 2017

Senses: What you see is how you feel

Science & Technology EMBL’s Hiroki Asari investigates how our internal state can change the way our eyes work

2017

sciencescience-technology

29 May 2017

Welcome: James Sharpe

People & Perspectives Meet the head of EMBL's new Barcelona site, James Sharpe

2017

people-perspectivesscience

25 May 2017

Sorting out HIV

Science & Technology An EMBL collaboration devises a new method that could speed up vaccine development for HIV

2017

sciencescience-technology

24 May 2017

Humans of EMBL: Senses

Lab MattersPeople & Perspectives People across EMBL’s sites reflect on the ways they perceive their world

2017

lab-matterspeople-perspectives

11 May 2017 HipSci stem cells

HipSci: The human stem cell bank

Science & Technology Introducing one of the largest collections of high-quality human induced pluripotent stem cells

2017

sciencescience-technology

8 May 2017

Obituary: Riccardo Cortese

People & Perspectives The life science community is deeply saddened by the loss of EMBL alumnus Riccardo Cortese

2017

alumnipeople-perspectives

5 May 2017

Welcome: Jamie Hackett

People & Perspectives Meet Monterotondo’s new group leader for epigenetic reprogramming and inheritance, Jamie Hackett

2017

people-perspectivesscience

3 May 2017

Futures: Phosphatases

Science & Technology ERC grantee Maja Köhn shares her vision for the next ten years

2017

sciencescience-technology

2 May 2017

Hungary becomes EMBL member state

EMBL AnnouncementsLab Matters EMBL welcomes its 23rd member state, with a promising collaboration already in place

2017

embl-announcementslab-matters

27 April 2017

Illuminating insulin release

Science & Technology EMBL researchers develop an optical method for measuring the release of insulin from single cells

2017

sciencescience-technology

25 April 2017

Embryos use ancient viral DNA

Science & Technology EMBL scientists detect important function of genetic sequence our ancestors assimilated from a virus

2017

sciencescience-technology

13 April 2017 Artist's interpretation of the mouse epigenetic clock.

A race against the ageing clock

Science & Technology EMBL-EBI researchers identify mouse epigenetic clock that could help scientists understand ageing

2017

sciencescience-technology

12 April 2017

Obituary: Konrad Müller

Lab MattersPeople & Perspectives EMBL alumnus Konrad Müller has sadly passed away

2017

lab-matterspeople-perspectives

11 April 2017

Experience life in the lab!

Lab Matters Call for applications for school students to join ‘Summer in Science’ in Monterotondo

2017

lab-matters

5 April 2017

When science meets management

Lab Matters New Master's programme for research infrastructure managers – set to launch autumn 2017

2017

eventslab-matters

29 March 2017

Obituary: Anna Tramontano

Lab MattersPeople & Perspectives Anna Tramontano, bioinformatics pioneer and EMBL alumna, has passed away

2017

lab-matterspeople-perspectives

29 March 2017

A tribute to Anna Tramontano

Lab MattersPeople & Perspectives Janet Thornton reflects on the contributions of EMBL alumna Anna Tramontano

2017

lab-matterspeople-perspectives

24 March 2017

John Kendrew’s legacy

Lab MattersPeople & Perspectives “Without John Kendrew there would have been no EMBL,” wrote Ken Holmes

2017

lab-matterspeople-perspectives

24 March 2017

Futures: The dark proteome

Science & Technology ERC grantee Edward Lemke shares his vision for the next ten years

2017

sciencescience-technology

21 March 2017

Welcome: Monika Lachner

Lab MattersPeople & Perspectives EMBL’s new Academic Coordinator and Dean of Graduate Studies Monika Lachner leads programmes that help young scientists to flourish

2017

lab-matterspeople-perspectives

13 March 2017

Futures: Brain evolution

Science & Technology ERC grantee Detlev Arendt shares his vision for the next ten years

2017

sciencescience-technology

13 March 2017

Futures: Genome regulation

Science & Technology ERC grantee Eileen Furlong shares her vision for the next ten years

2017

sciencescience-technology

6 March 2017

Pathways: Life science investment

People & Perspectives EMBL alumnus Joep Muijrers talks about making the transition from science into business

2017

alumnipeople-perspectives

2 March 2017

Metabolism matters

Science & Technology Differentiated and undifferentiated cells get energy in different ways, sensor made at EMBL shows

2017

sciencescience-technology

28 February 2017

SESAME: a light in the desert

People & Perspectives EMBL alumna Zehra Sayers key driver of the Middle East’s first synchrotron project

2017

alumnipeople-perspectives

23 February 2017

Building labs with flies

People & Perspectives Flies can do a lot for science, inside and outside the lab. EMBL alumna Isabel Palacios explains how

2017

alumnipeople-perspectives

16 February 2017

New EMBL and GSK collaboration

ConnectionsLab Matters GSK and EMBL have signed an agreement to enhance understanding of disease and drug mechanisms

2017

connectionslab-matters

16 February 2017

Beamline 14’s legacy

Lab MattersScience & Technology Beamline BM14 in Grenoble shuts down, continues collaboration with India

2017

lab-mattersscience-technology

14 February 2017

Lipids in real time

Science & Technology A new technique developed at EMBL reveals the way fats interact with other molecules in cells

2017

sciencescience-technology

13 February 2017

Genetic switches can change shape

Science & Technology EMBL scientists discovered that common mutations can change the shape of gene promoters

2017

sciencescience-technology

31 January 2017 John Kendrew with model of myoglobin in progress. © MRC Laboratory of Molecular Biology

Reflections by Sir John Kendrew

Lab MattersPeople & Perspectives In this interview from the EMBL Archive, Sir John Kendrew reflects on his time leading 'the Lab'.

2017

lab-matterspeople-perspectives

26 January 2017

Degrees of excellence

Lab Matters Helke Hillebrand on leaving EMBL after 9 years as Academic Coordinator and Dean of Graduate Studies

2017

lab-matters

25 January 2017 Wojciech Galej, new group leader at EMBL

Welcome: Wojciech Galej

People & Perspectives New group leader Wojciech Galej investigates RNA-protein complexes involved in gene expression

2017

people-perspectivesscience

21 December 2016

How flu steals your RNA

Science & Technology Understanding how the flu virus steals host RNA offers hope of new drugs

2016

sciencescience-technology

21 December 2016 fluorescence image of receptor degredation

New insights into receptor balancing

Science & Technology Inducible mechanism found by EMBL scientists links receptor degradation and replenishment

2016

sciencescience-technology

20 December 2016 A 3D print-out of beta-galactosidase

Happy anniversary, PDBe!

Lab MattersScience & Technology Ewan Birney's nine "Structures of Christmas" celebrate 20 years of PDBe

2016

lab-mattersscience-technology

20 December 2016

Opinion: Fail again, fail better

Lab MattersPeople & Perspectives Iain Mattaj on failure, adventure, determination and the Scientific Method

2016

lab-matterspeople-perspectives

19 December 2016 The 2016 intake of EMBL PhD students

First year PhDs complete their training

Lab Matters For the past two months EMBL Heidelberg has hosted around 60 first year PhD students from EMBL’s International PhD Programme (EIPP). From thousands of applicants, the students were selected from over 40 countries to work on their PhD research at one of EMBL’s five sites – Grenoble, Hamburg,…

2016

lab-matters

14 December 2016

New Crystallography platform inaugurated

EMBL AnnouncementsLab Matters A new crystallography platform in Grenoble opens the door to new technological developments

2016

embl-announcementslab-matters

13 December 2016

Study offers approach to treating pain

Science & Technology Research on the effect of nerve cell stiffness on sensitivity to touch could lead to new painkillers

2016

sciencescience-technology

8 December 2016

10th PEPC course in Hamburg

Connections The PEPC course celebrated its 10th anniversary in Hamburg from the 12 – 20 September this year

2016

connectionsevents

7 December 2016

Cycle of life

Science & Technology Paul Nurse’s failed experiment inspired a career that would uncover key mechanisms of cell division

2016

sciencescience-technology

5 December 2016 OmniPath cover image Nature Methods 2016

Omnipath for signalling pathways

Science & Technology New method combines signalling pathway data resources to improve systems biology research

2016

sciencescience-technology

2 December 2016

Catching the chaperone in the act

Science & Technology How Christian Löw’s failed experiment led to an unexpected scientific journey

2016

sciencescience-technology

1 December 2016

Design for life

Lab MattersPeople & Perspectives EMBL’s Petra Riedinger retires after 40 years producing posters, graphics, artwork and more

2016

lab-matterspeople-perspectives

29 November 2016

Capturing life in perspective

Lab MattersScience & Technology How a team of scientists and artists at EMBL transformed microscopy data into stunning 3D images

2016

lab-mattersscience-technology

24 November 2016

What would it take to regrow an arm?

Science & Technology Exploring what it would take to regrow a lost limb, and what we might learn along the way

2016

sciencescience-technology

24 November 2016 SPIM image of Medaka juveniles. Photo: EMBL/Philipp Keller

Thinking in 3D

People & Perspectives Ernst Stelzer earns 2016 Lennart Philipson award for advances in light sheet microscopy

2016

alumnipeople-perspectives

24 November 2016

Chromatin cartographer

People & Perspectives EMBL alumnus Jop Kind reflects on the questions that led him to this year’s John Kendrew Award

2016

alumnipeople-perspectives

22 November 2016

New mechanism for cancer gene activation

Lab MattersScience & Technology EMBL study finds that rearranging how DNA packs the nucleus can activate cancer genes

2016

lab-mattersscience-technology

18 November 2016 Artist interpretation of a human epigenome.

BLUEPRINT project delivers

Science & Technology BLUEPRINT: EMBL-EBI and the push to decipher the blood epigenome

2016

sciencescience-technology

17 November 2016

New insights into RNA Polymerase I

Science & Technology Cryo EM reconstruction of RNA Polymerase I reveals details of how molecule binds and transcribes DNA

2016

sciencescience-technology

11 November 2016

Big data, cool servers

Lab Matters Upgraded server room is ready to take the heat at EMBL Grenoble

2016

lab-matters

10 November 2016

Review: Lab Girl

Lab MattersPeople & Perspectives Hope Jahren’s autobiography educates and delights

2016

lab-matterspeople-perspectives

4 November 2016 Sequence bundles: screen shot

Collaboration is beautiful

Science & Technology Where design meets bioinformatics, new scientific perspectives abound.

2016

sciencescience-technology

3 November 2016

Spiral growth

Science & Technology What happens when plant's leaf-placing feedback loop isn't quite right

2016

sciencescience-technology

27 October 2016

Welcome to EMBL: Robert Prevedel

People & Perspectives Robert Prevedel develops deep-tissue microscopy for scientists to peer deep inside living organisms

2016

people-perspectivesscience

20 October 2016

Diving into Autumn

Connections Participants learn about EMBL’s ocean biodiversity research at the Fall Gala

2016

connectionsevents

17 October 2016

Opinion: Is your mind playing tricks on you?

Lab MattersPeople & Perspectives We catch up with neuroscientist Craig Stark, speaker at the EMBL/EMBO Science and Society Conference

2016

lab-matterspeople-perspectives

14 October 2016 Global Alliance for Genomics and Health logo

Ewan Birney to lead Global Alliance

EMBL AnnouncementsLab Matters Global Alliance for Genomics and Health chose Birney to lead efforts to bring genomics to the clinic

2016

embl-announcementslab-matters

4 October 2016

In pursuit of flat growth in leaves

Science & Technology EMBL scientists investigate how leaves grow flat to efficiently capture sunlight

2016

sciencescience-technology

29 September 2016

EMBL at NatureJobs careers fair

ConnectionsLab Matters EMBL recently attended the Naturejobs Career Expo, advising scientists about their career options

2016

connectionslab-matters

27 September 2016 CORBEL supports scientists working on advanced research projects in areas from advanced imaging, high-throughput screening and mouse mutant phenotyping. IMAGE: CORBEL

Accelerate your research with CORBEL

Lab MattersScience & Technology CORBEL Open Call launches October 2016, for access to 15 facilities and 8 research infrastructures

2016

lab-mattersscience-technology

27 September 2016 EMBL events offer some of the best training and development for life researchers in the world. PHOTO: EMBL Course and Conference Office

Become an EMBL events reporter

Lab Matters Take part in an EMBL conference or symposium for free as an EMBL events reporter

2016

eventslab-matters

26 September 2016

Turning up the heat on drug side effects

Science & Technology Side-effects of leukaemia drug explained, reveal possibility of repurposing to treat other diseases

2016

sciencescience-technology

26 September 2016 Mikhail Savitski. PHOTO: Marietta Schupp/EMBL Photolab

Welcome to EMBL: Mikhail Savitski

People & Perspectives New head of Proteomics Core Facility also runs stability proteomics lab

2016

people-perspectivesscience

21 September 2016

Powering proteomics progress

People & Perspectives EMBL alumnus Angus Lamond is driving forward new ways to explore the proteome

2016

alumnipeople-perspectives

20 September 2016 Inauguration of the Szilárd Library in the late 1970s, led by John Kendrew (right). PHOTO: EMBL

Szilárd Library: An open book

People & Perspectives Past meets present as Library head Ioanna Ydraiou interviews EMBL’s first librarian

2016

alumnipeople-perspectives

13 September 2016

New drug candidate unleashed for TB

Science & Technology EMBL researchers help to design a lead compound active against four different pathogens

2016

sciencescience-technology

13 September 2016

Opinion: 2006, a year of champagne

Lab MattersPeople & Perspectives Stephen Cusack looks back on the early days of his collaboration with Anacor developing anti-infectives

2016

lab-matterspeople-perspectives

13 September 2016 BioStudies logo

BioStudies: The Data Bento Box

Lab MattersScience & Technology A new repository helps identify emerging trends in data-driven science.

2016

lab-mattersscience-technology

30 August 2016 Data by Natalia Wesolowska has been visualised in 3D stereoscopic view, as an anaglyph and a 3D lenticular poster by Stefan Günther & Gustavo de Medeiros at EMBL

See data in a new light

Science & Technology 3D printing, gaming, virtual reality and lenticular posters bring new perspectives to research

2016

sciencescience-technology

30 August 2016 Francesco Iorio, an EMBL-EBI/Sanger Interdisciplinary Postdoc and now a senior bioinformatician at EMBL-EBI, strives to be "a great dad, as well as a great researcher". PHOTO: Robert Slowley

Postdocs of EMBL

Lab MattersPeople & Perspectives Turning the spotlight on the diverse universe of EMBL’s 200-strong postdoc community

2016

lab-matterspeople-perspectives

30 August 2016

Gene editing 3.0

Science & Technology Emmanuelle Charpentier sheds light on how CRISPR–Cas9 went from side project to global revolution

2016

sciencescience-technology

30 August 2016

Swimming against the tide

People & Perspectives "If I have an aim, I’ll find a solution" – meet EMBL alumnus Jochen Wittbrodt

2016

alumnipeople-perspectives

30 August 2016 European Commissioner Carlos Moedas. PHOTO: European Commission

From potential to policy

Lab MattersPeople & Perspectives Integration, collaboration and openness on agenda for Carlos Moedas, European Commissioner for Research

2016

lab-matterspeople-perspectives

30 August 2016

Atomic proportions

Connections EMBL and ESRF scientists and mechanics work together on upgrade for one of Europe’s big X-ray sources

2016

connectionsscience

30 August 2016

Fundraising dimensions

Connections Alumnus and entrepreneur Marc Zabeau speaks at inaugural Life Science Funders and Foundations event

2016

connectionsevents

30 August 2016 IMAGE: EMBL/Spencer Phillips

Form follows function

Science & Technology 'The PDB plays a crucial role in structural biology research and development'

2016

sciencescience-technology

30 August 2016 Bruce Alberts, formerly President of the National Academy of Sciences, Editor-in-Chief of Science, and US Science Envoy; now a Chancellor’s Leadership Chair at the University of California. PHOTO: The University of California/Tom Kochel

Inspire change in science

Lab MattersPeople & Perspectives Bruce Alberts on fixing the broken academic career pipeline

2016

lab-matterspeople-perspectives

30 August 2016

Pathways: Community management

People & Perspectives Scientific community manager, alumnus Aidan Budd, connects people with shared interests, values, goals

2016

alumnipeople-perspectives

29 August 2016

Awards & Honours

EMBL AnnouncementsLab Matters EMBL scientists regularly receive prestigious awards – meet the latest honourees.

2016

embl-announcementslab-matters

26 August 2016 EMBL team leader Georg Zeller. PHOTO: EMBL/Marietta Schupp

Welcome: Georg Zeller

Science & Technology Team leader investigates how the gut microbiome could relate to human diseases

2016

sciencescience-technology

10 August 2016 Paris at night. IMAGE: NASA (M. Justin Wilkinson, Texas State University, Jacobs Contract at NASA-JSC)

Life in the periphery

Science & Technology Storage of pre-made nuclear pores allows for rapid cell division in fruit fly embryos

2016

sciencescience-technology

4 August 2016 45 pupils from Saarland, Germany visit EMBL-EBI

Just try!

Lab Matters German students visit EMBL-EBI on a tour to explore a new culture and different career paths

2016

lab-matters

28 July 2016 Landline vs. smartphone: the RNA-binding domain lets proteins do more than just talk to other proteins

Discovering protein smartphones

Science & Technology New technique reveals uncharted docking sites in RNA-binding proteins

2016

sciencescience-technology

7 July 2016

Mapping early development

Science & Technology “Like getting hold of a microscope for the first time”

2016

sciencescience-technology

30 June 2016

Scientific twins

Science & Technology Collaborations shorten distance between EMBL Heidelberg, Germany, and CEITEC in Brno, Czech Republic

2016

sciencescience-technology

30 June 2016 European Union flag. PHOTO: MPD01605 (CC BY-SA 2.0)

Key facts about the impact of Brexit on EMBL

Lab MattersPeople & Perspectives In a time of great uncertainty, key facts about EMBL's status, collaborations, funding and recruitment

2016

lab-matterspeople-perspectives

29 June 2016 Alba Diz-Muñoz. PHOTO: Hugo Neves/EMBL Photolab

Welcome: Alba Diz-Muñoz

People & Perspectives New group leader combines physics and biology to answer the 'hows' of cell movement

2016

people-perspectivesscience

24 June 2016

Bork lab peers gather

Lab Matters 27 former Bork lab members joined Peer for a full-day get-together this summer

2016

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16 June 2016 Emiko Uchikawa in her lab at EMBL in Grenoble. IMAGE: Isabelle Kling/EMBL

Found in translation

Science & Technology Studying at EMBL in Grenoble helps Japanese postdoc see her native country through different eyes

2016

sciencescience-technology

14 June 2016

How cells bag their rubbish

Science & Technology How cells eliminate protein deposits that can lead to neurodegenerative disorders

2016

sciencescience-technology

9 June 2016

Behind the scenes: Audiovisual

Lab Matters Meet the secret timekeepers of EMBL events: AV technicians Sean Nightingale and Jan Abda

2016

eventslab-matters

27 May 2016 Italy-based alumni gathered for the ‘EMBL in Italy’ event on 27 May to learn about the focus of researchers at EMBL’s Monterotondo site. PHOTO: EMBL/Isabelle Kling

Italian interconnections

Connections Marco Tripoldi and Valeria Carola join colleagues and peers at gathering of Italy-based alumni

2016

alumniconnections

23 May 2016 UK-based EMBL alumni gather at Trinity Hall, Cambridge in May 2016. PHOTO: Robert Slowley

Making business in Britain

Connections Abel Ureta-Vidal and Louise Modis join colleagues and peers at gathering of UK-based alumni

2016

alumniconnections

20 May 2016 Hugo Sarmento aboard Tara. PHOTO: Tara Oceans/Hugo Sarmento

Supporting science at sea

People & Perspectives Dozens of postdocs boosted their careers with a voyage aboard the Tara Oceans research schooner

2016

people-perspectivesscience

10 May 2016 A small loop (green) of the atomic structure of DAPK shown to be crucial for dimer formation and binding with its signaling partner Calmodulin. IMAGE: Petra Riedinger/EMBL

Enzyme with a dual-purpose loop

Science & Technology Unexpected results: structure of DAPK enzyme reveals dual-purpose loop

2016

sciencescience-technology

9 May 2016 Kikusui spent 10 days this March in the Gross lab at EMBL brainstorming the neural mechanisms of social behaviour. PHOTO: Cornelius Gross

The pheromones behind romance

Science & Technology A perfect match: behaviourist Takefumi Kikusui visits the Gross group to explore animal attraction

2016

sciencescience-technology

21 April 2016 EMBL scientists are discovering and understanding the waves and rhythms inside us. ILLUSTRATION: Aad Goudappel, Rotterdam

The rhythms in life

Science & Technology How EMBL scientists are discovering and understanding the waves and rhythms inside us

2016

sciencescience-technology

21 April 2016 Florent Cipriani (right) developed CrystalDirect™ together with Josan Marquez (left) PHOTO: EMBL

The man behind the machine

Science & Technology Florent Cipriani talks about his passion for developing beamline instrumentation

2016

sciencescience-technology

21 April 2016 Giorgia Guglielmi 's PhD project puts development in a new light. PHOTO: EMBL Photolab/Marietta Schupp

Light control

Science & Technology EMBL PhD project puts development in a new light

2016

sciencescience-technology

21 April 2016 Neuroscientist and stand-up comic Sophie Scott presented a EMBL Science and Society Forum lecture on laughter. PHOTO: University College London

Branches: Laughing matter

People & Perspectives Neuroscientist and comedian Sophie Scott explains the complexity and social importance of laughter

2016

eventspeople-perspectives

21 April 2016

Reviews: Life’s Blueprint

Lab Matters Review of 'Life’s Blueprint: The Science and Art of Embryo Creation' by Benny Shilo

2016

lab-matters

21 April 2016 Keith Williamson retires after 14 years at EMBL. PHOTO: EMBL/Udo Ringeisen

Admin ability

People & Perspectives EMBL's ninth administrative director Keith Williamson looks back at 14 years at the Laboratory

2016

alumnipeople-perspectives

21 April 2016 An extract from Edmond Baudoin's original artwork – see the complete image. IMAGE: Edmond Baudoin / Cédric Villani / EMBL archive DE 2324 P-BAU -1

From the Archive: The Moon Dreamers

Lab MattersPeople & Perspectives Illustrator Edmond Baudoin donates an original artwork to the EMBL Archive

2016

lab-matterspeople-perspectives

21 April 2016 Both the John Kendrew and Lennart Philipson Awards consist of a gold medal and a cash prize of €5,000, presented in recognition of the very special work of alumni. PHOTO: EMBL Photolab

Alumni awards

EMBL Announcements EMBL rewards the special work of alumni through the John Kendrew and Lennart Philipson awards.

2016

alumniembl-announcements

21 April 2016 Anne Ephrussi wears the medal of the Order of Légion d’Honneur, the highest distinction in France. PHOTO: EMBL Photolab/Marietta Schupp

Awards & Honours

Lab Matters EMBL scientists regularly receive prestigious awards – meet the latest honourees.

2016

lab-matters

21 April 2016 Jozef Ševcik at the X13 beamline at the DORIS ring in Hamburg. PHOTO: Rostislav Skrabana

Slovakian synergies

People & Perspectives Meet a driving force behind collaborations with the Slovak Republic, alumnus Jozef Ševčik

2016

alumnipeople-perspectives

21 April 2016 New Chair of the EMBL Alumni Association Gareth Griffiths. Photo: EMBL/Mehrnoosh Rayner

Close association

People & Perspectives Gareth Griffiths, new Chair of the Alumni Association, reveals his many perspectives of EMBL

2016

alumnipeople-perspectives

21 April 2016 CrystalDirect robot control software: signal from a video camera monitoring the laser working area within a microplate (centre), used to locate the aperture (green trace) and cutting shape (red line), and to select final position of pin tip relative to the crystal (red oval). IMAGE: Zander, U, et al.

Crystals in the beamlight

Science & Technology CrystalDirect, developed at EMBL, automates crystal preparation for X-ray analysis

2016

sciencescience-technology

14 April 2016

Taking science to new dimensions

People & Perspectives Alumna Angela Relogio tells us about her passion for science, communication and mentoring

2016

alumnipeople-perspectives

7 April 2016

Welcome: Hiroki Asari

People & Perspectives Why does a cookie look different depending on how hungry you are? Neuroscientist Asari wants to find out

2016

people-perspectivesscience

31 March 2016 The insights should improve therapies where T-cells (green and red) are modified to attack cancer cells (blue, center). IMAGE: NICHD/J. Lippincott-Schwartz

Designing gene therapy

Science & Technology Information on structure of molecule used for genome engineering yields increased efficiency

2016

sciencescience-technology

24 March 2016 Zernicka-Goetz lab, University of Cambridge

Foetus, or placenta?

Science & Technology Subtle genetic differences destine cells to placenta or animal, very early in embryo development

2016

sciencescience-technology

21 March 2016 EMPIAR

Supporting the bioimaging revolution

Science & Technology Commentary in Nature Methods introduces the EMPIAR resource and gives glimpse of future developments

2016

sciencescience-technology

21 March 2016 First complete, real-time recording of starfish egg cell eliminating centrioles shows it handles mature ‘mother’ centrioles (green) and immature ‘daughter’ centrioles (purple) differently.

Mothers and daughters

Science & Technology 1st real-time video of starfish egg cell eliminating crucial structures, to ensure embryo viability

2016

sciencescience-technology

21 March 2016

Finding the way with X-Ray

Science & Technology New technique uses X-rays to find landmarks when combining fluorescence and electron microscopy

2016

sciencescience-technology

18 March 2016

Forgetting to learn

Science & Technology Neural mechanisms in mouse brains indicate that we actively forget as we learn

2016

sciencescience-technology

8 March 2016 PHOTO: Pixabay (CC0 Public Domain)

Childcare at EMBL events

Lab Matters EMBL PlayLab now available at 22 conferences hosted in Heidelberg

2016

eventslab-matters

7 March 2016 During cell division, DNA (purple) must be correctly grouped and divided between daughter cells. IMAGE: Nasser Rusan, National Institutes of Health (NIH)

A cohesive structure

Science & Technology Structural insights into how cohesin keeps DNA together during the cell cycle

2016

sciencescience-technology

3 March 2016 Colorised scanning electron micrograph of red blood cell infected with malaria parasites (blue); uninfected cells with a smooth red surface. IMAGE: (CC BY 2.0)

Mapping malaria

Science & Technology First detailed atlas of start points for genes expression in malaria-causing parasite

2016

sciencescience-technology

16 February 2016 The stem cell equivalent of an anti-wrinkle cream advert. Credit: EMBL/Hanna Sladitschek

Forever young

Science & Technology How stem cells resist change

2016

sciencescience-technology

12 February 2016 Cells formed circles where blinking happened in a wave, rolling outwards from the centre. IMAGE: EMBL/C.Tsiairis

In sync

Science & Technology What do cells in an embryo have in common with schools of fish, swarms of fireflies, and applauding audiences?

2016

sciencescience-technology

11 February 2016 The 3D structure shows how two transcription factors influence one another’s binding to a specific stretch of DNA – an interaction that is crucial for a heart to develop healthily. IMAGE: EMBL/C.Müller

True Love

Science & Technology How transcription factors interact to create a heart

2016

sciencescience-technology

11 February 2016 Report on the value and impact of EMBL-EBI underscores profound utility of open data

What is the value of open data?

Lab Matters Independent analysis of EMBL-EBI underscores the value and impact of open data in the life sciences

2016

lab-matters

10 February 2016 Plankton plays an important role in sequestering carbon in the ocean. IMAGE: Christian Sardet/Tara Océans/CNRS Photothèque

The carbon hijacking network

Science & Technology Plankton network linked to ocean's biological carbon pump revealed

2016

sciencescience-technology

8 February 2016 Biogen joins the CTTV

Biogen joins CTTV

ConnectionsLab Matters Pioneering target validation collaboration expands to accelerate drug discovery research.

2016

connectionslab-matters

4 February 2016 Rob Meijers and Stephane Boivin at the Sample Preparation and Characterisation facility. PHOTO: EMBL/Rosemary Wilson

How to make a protein happy

Science & Technology Protein screens developed at EMBL Hamburg now commercially available

2016

sciencescience-technology

28 January 2016 Bernard Jacrot in the late 1960s. IMAGE: ILL

Obituary: Bernard Jacrot

People & Perspectives Former Head of EMBL Grenoble passed away on 21 January 2016 at the age of 89

2016

alumnipeople-perspectives

25 January 2016 Kim Remans heads EMBL's Protein Expression and Purification Core Facility. PHOTO: EMBL Photolab/Marietta Schupp

Welcome: Kim Remans

Lab MattersPeople & Perspectives "We’re open! We’re open to working with everybody, we’re open to new things."

2016

lab-matterspeople-perspectives

18 January 2016 A peroxisome containing protein crystals is hit by a free-electron laser. IMAGE: EMBL/CFEL, Thomas Seine

The cellular crystal factory

Science & Technology Hamburg collaborators analyse protein crystals inside the cells that made them.

2016

sciencescience-technology

15 January 2016 Full length CTP1L protein (green) in complex with truncated C-terminal domain (violet). IMAGE: Rob Meijers

One gene, two proteins, one complex

Science & Technology Further insights into how viral enzymes degrade the cell walls of Clostridia bacteria.

2016

sciencescience-technology

13 January 2016 Vasily Sysoev, right, hosts Prakash Balasubramanian and Lars Steinmetz at Science Tonight.

Playing with science

People & Perspectives Scientist and showman: PhD student Vasily Sysoev shares his passion for outreach.

2016

eventspeople-perspectives

17 December 2015 Digital zebrafish embryo provided the first complete developmental blueprint of a vertebrate in 2008. IMAGE: EMBL/Keller et al.

SPIM doctors

Science & Technology From initial development to a start-up company: Selective Plane Illumination Microscopy (SPIM) at EMBL.

2015

sciencescience-technology

17 December 2015

What’s on in 2016

Connections With 28 conferences and 57 courses, 2016 will be EMBL’s most eventful year to date.

2015

connectionsevents

14 December 2015 Scientists can now view and track the first days of a mouse embryo’s life. IMAGE: EMBL/ Julius Hossain

Turning point of a lifetime

Science & Technology New microscope can record the first days of a mouse embryo’s life

2015

sciencescience-technology

11 December 2015 Periodic Table of Protein Complexes, Ahnert et al., Science 2015

Periodic table of protein complexes

Science & Technology Making it easier to visualise, understand and predict how proteins combine to drive biological processes.

2015

sciencescience-technology

9 December 2015 Standing room only at the second EMBL Movie Night. PHOTO: EMBL/Marietta Schupp

Dinosaurs, DNA and Dolly

Lab Matters Two PhD students sink their teeth into the science and speculations of Jurassic Park.

2015

eventslab-matters

2 December 2015 Gut bacteria are more affected by metformin than by the type-2 diabetes it is prescribed to treat. IMAGE: Courtesy of Pacific Northwest National Laboratory (BY-NC-SA)

Drugging bacteria

Science & Technology Commonly used diabetes drug metformin impacts gut bacteria more than disease itself

2015

sciencescience-technology

30 November 2015 on course - the comprehensive catalogue for biomedical training in Europe

Toolkit for trainers

Lab Matters The new Toolkit for Trainers, an online resource hosted at EMBL-EBI, helps biomedical science trainers create and explore new ways of teaching.

2015

lab-matters

30 November 2015 Malte Paulsen. PHOTO: EMBL Photlab/Marietta Schupp

Welcome: Malte Paulsen

Lab MattersPeople & Perspectives "There’s nothing nicer than seeing a user leave the facility happy"

2015

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25 November 2015

Humans of EMBL

Lab MattersPeople & Perspectives Compelling short stories that shine light on the life and work of EMBL staff.

2015

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25 November 2015 Roland Block, Head of Human Resources at EMBL. PHOTO: EMBL Photolab/Marietta Schupp

Walking the talk in HR

Lab MattersPeople & Perspectives Roland Block, EMBL's Head of HR, on emphasising the ‘human’ in human resources.

2015

lab-matterspeople-perspectives

25 November 2015 IMAGE: EMBL-EBI/Spencer Phillips

What makes us human? Or not…

Science & Technology From jumping genes to organ transplants, the non-human features that make us human.

2015

sciencescience-technology

25 November 2015 Agustín Fuentes. PHOTO: Lawrence Smith/Fairfax media

Branches: What makes humans tick?

People & PerspectivesScience & Technology What really sets humans apart? Forming societies, teaching and compassion, says Agustin Fuentes.

2015

people-perspectivesscience-technology

25 November 2015 ILLUSTRATION: Aad Goudappel

Using humans as a model organism

Lab MattersPeople & Perspectives Ewan Birney on the risks, rewards and realities of studying humans as a model species.

2015

lab-matterspeople-perspectives

25 November 2015 Halldór Stefánsson, EMBL Science & Society Programme Manager. PHOTO: EMBL/Adam Gristwood

Of humans and animals

Lab Matters Halldór Stefánsson on the long history of complex interactions between humans and animals.

2015

lab-matters

25 November 2015 EMBL Heidelberg hosted a day's discussion on what makes us human. PHOTO: Jörg Langowski

Being human beings

People & Perspectives Highlights from the 'What makes us human?' symposium at EMBL Heidelberg.

2015

eventspeople-perspectives

25 November 2015 Reviews of two of the best popular science books of 2014, exploring the unreasonable rise of Homo sapiens.

Reviews: Homo sapiens

Lab MattersPeople & Perspectives Postdoc Thibaut Brunet reviews two popular science books that explore the rise of Homo sapiens.

2015

lab-matterspeople-perspectives

25 November 2015 Question mark

Q&A: Biophysics

Lab MattersPeople & Perspectives What does a physicist do in a biology lab?

2015

lab-matterspeople-perspectives

24 November 2015

Awards & Honours

EMBL AnnouncementsLab Matters EMBL scientists regularly receive prestigious awards – meet the latest honourees.

2015

embl-announcementslab-matters

24 November 2015 Sybrand van der Zwaag is scientific director of the Delft Centre for Materials in the Netherlands. PHOTO: Photo: Delft University of Technology

Pathways: Open letter to young scientists

Lab MattersPeople & Perspectives Sybrand van der Zwaag gives his five top tips for young researchers thinking about their next move.

2015

lab-matterspeople-perspectives

24 November 2015 No coincidence: organisers of this year’s PhD Symposium gather at EMBL Heidelberg 22–24 October for Just by Chance? Randomness and variability shaping biology. PHOTO: EMBL Photolab/Marietta Shupp

EMBL in pictures

Lab Matters A snapshot of the many activities and events that took place in the world of EMBL this Autumn.

2015

eventslab-matters

23 November 2015 More than 600 'diplomas' were awarded to budding crystallographers for successfully fishing crystals! PHOTO: DESY 2015

High-throughput event

Lab Matters Energy, enthusiasm and endurance on tap as thousands attend 12-hour Hamburg Night of Science.

2015

eventslab-matters

19 November 2015 When illuminated with a laser, individual cells (bright yellow) within the fruit fly embryo cannot contract. This novel optogenetic approach helped to get insights into how tissues bend.

Lighting up development

Science & Technology Using lasers to shed light on how tissues get into shape

2015

sciencescience-technology

12 November 2015 Visitors folding a microscope from paper. PHOTO: EMBL/Angela Michel

Enlightening experiments

Lab Matters From paper microscopes to zebrafish embryos, EMBL Science Days stand had something for everyone.

2015

eventslab-matters

9 November 2015 Bertone and Smith: Unpacking embryonic pluripotency

Unpacking embryonic pluripotency

Science & Technology Embryology, genomics and bioinformatics combine to identify factors regulating mammalian pluripotency.

2015

sciencescience-technology

6 November 2015 EMBL staff, alumni and their networks gather for the first Swiss chapter meeting. PHOTO: EMBL/Mehrnoosh rayner

Alumni meet in Switzerland

Connections Behind the scenes of the EMBL alumni chapter meeting in Zürich, Switzerland.

2015

alumniconnections

4 November 2015

Shaking hands with starfish

Lab Matters Science met business and strangers became friends at the first Friends of EMBL Ladies Night.

2015

eventslab-matters

30 October 2015

One hard pull

Science & Technology Fibres that pull membrane to form a vesicle exert a force that’s 2500 times a yeast cell’s own weight

2015

sciencescience-technology

29 October 2015 Enzyme Portal relaunched

Enzyme research made easier

Science & Technology Enzyme Portal makes it easier to explore all enzyme-related data in EMBL-EBI’s public resources.

2015

sciencescience-technology

26 October 2015

A whole new ball game

Lab Matters Hamburg researchers have a ball creating game to explain transporter protein mechanism.

2015

lab-matters

23 October 2015 EMBL Benelux alumni event involved speakers and participants from Belgium, the Netherlands and Luxembourg. PHOTO: EMBL/Mehrnoosh Rayner

Alumni meet in Belgium

Connections Behind the scenes of the EMBL-VIB alumni Benelux meeting.

2015

alumniconnections

15 October 2015 MinION™ USB-attached miniature sensing device.

Mini DNA sequencer tests true

Science & Technology Evaluation of MinION™ sequencer finds performance and reliability consistently good.

2015

sciencescience-technology

14 October 2015 single-cell transcriptomics reveals biologically relevant heterogeneity in expression

A snapshot of stem cell expression

Science & Technology Study of mouse embryonic stem cells reveals new genes involved in the stem-cell regulatory network.

2015

sciencescience-technology

14 October 2015

Lighting the way

Lab MattersScience & Technology A microscopy technique is poised to shine new light on biological questions: as sheets of light can scan everything from developing embryos to single cells or functioning brains, a technique called light-sheet microscopy is gaining traction. It enables scientists to observe living cells in three…

2015

lab-mattersscience-technology

9 October 2015 The ultrafast and yet selective binding allows the receptor (gold) to rapidly travel through the pore filled with disordered proteins (blue) into the nucleus, while any unwanted molecules are kept outside. IMAGE: Mercadante /HITS

Floppy but fast

Science & Technology Spaghetti-like proteins are surprisingly effective 'keys'

2015

sciencescience-technology

5 October 2015

Nobel connections

ConnectionsLab Matters Amidst the excitement of Nobel Week, behind the scenes of the annual Lindau Nobel Laureate Meetings.

2015

connectionslab-matters

2 October 2015 The 1000 Genomes Project: a timeline

A lasting legacy

Science & Technology 1000 Genomes Project pushed technologies and knowledge forward to understand what is 'normal' human genetic variation

2015

sciencescience-technology

1 October 2015 What do diatoms really do? Chris Bowler would like to know. IMAGE: Sebastien Colin

Marine mysteries

Science & Technology From the role of diatoms to how life evolved - scientists' pressing questions about life in the sea.

2015

sciencescience-technology

1 October 2015

Behind the scenes: Event management

People & Perspectives Long-time events pro Antje Seeck gives us her take on how to organise a successful conference.

2015

eventspeople-perspectives

30 September 2015 The 1000 Genomes Project tracked genetic variation across the globe. EMBL-EBI/Spencer Phillips

Finding links and missing genes

Science & Technology Missing a gene may not be a big deal – a conclusion from global catalogue of genetic changes.

2015

sciencescience-technology

29 September 2015 Lithuanian flag

Lithuania, new prospect member state

EMBL AnnouncementsLab Matters Sveiki Lietuva! Lithuania becomes EMBL’s fourth prospect member state.

2015

embl-announcementslab-matters

29 September 2015

Joining forces for events

Connections EMBL-Wellcome Genome Campus events collaboration showcases open, application-based science.

2015

connectionsevents

29 September 2015

Karsenti wins CNRS gold

EMBL AnnouncementsLab Matters Gold medal celebrates Eric Karsenti’s exceptional career and outstanding contributions to biology.

2015

embl-announcementslab-matters

29 September 2015 More than 170 representatives of EMBL and its four Nordic partnerships attending the annual meeting in September.

Northern highlights

ConnectionsLab Matters Renewals and reunions: EMBL’s Nordic partners look to the future.

2015

connectionslab-matters

28 September 2015

EMBL-EBI training news

EMBL Announcements Highlights from EMBL-EBI’s Training Programme: Open Day, revamped webpages, free webinar series.

2015

embl-announcementsevents

23 September 2015

Checkpoint architecture

Science & Technology A nuclear pore riddle: how can you use the same number of pieces to form two rings that fit inside each other?

2015

sciencescience-technology

22 September 2015

MASSIFly efficient

Science & Technology MASSIF-1 processes its 10,000th crystal, less than one year after the beamline became operational.

2015

sciencescience-technology

17 September 2015 The scientists combined data from a variety of techniques to better understand how rats – and humans – age. IMAGE: Brandon Toyama/Salk Institute

Ages apart

Science & Technology Multifaceted approach reveals how brain and liver age, helps explain why ageing brain loses plasticity.

2015

sciencescience-technology

14 September 2015 Erica Valentini. PHOTO: EMBL/Rosemary Wilson

From side-project to valuable resource

Lab MattersScience & Technology Introducing the Small Angle Scattering Biological Data Bank, developed at EMBL Hamburg.

2015

lab-mattersscience-technology

14 September 2015 Tara expeditions docks in London, September 2015, on its way to the UN Climate Change Conference in Paris. [PHOTO: Robert Slowley]

EMBL onboard Tara, London 2015

Connections Tara Oceans research vessel welcomes aboard scientists, policymakers and funders.

2015

connectionsevents

13 September 2015 A mosaic of portraits of former and present lab members. IMAGE: Pavel Tomancak

Ephrussi reunion: face-to-face

Lab Matters Ephrussi group alumni reunite in Heidelberg for a surprise birthday celebration.

2015

alumnilab-matters

11 September 2015

Driving science in Denmark

Connections Alumni Rune Linding and Guillermo Montoya join colleagues and peers at the first Danish chapter meeting.

2015

alumniconnections

10 September 2015 New method to study biological signalling networks

Clearing a path for cancer research

Science & Technology New computational method to study biological signalling networks in healthy and cancer cells.

2015

sciencescience-technology

9 September 2015 Vinton Cerf, Google Chief Internet Evangelist, and a "fathers of the Internet".

From packets to planets

People & Perspectives Insights from the evangelical Vint Cerf, a “founding father of the Internet”, during a visit to EMBL.

2015

eventspeople-perspectives

7 September 2015 Janosch Hennig. PHOTO: EMBL Photolab/Marietta Schupp

Welcome: Janosch Hennig

Lab MattersPeople & Perspectives “A structure alone is not so interesting, you need the biology too,” says new NMR-focused group leader

2015

lab-matterspeople-perspectives

7 September 2015 The 6th EMBO Meeting took place at the ICC in Birmingham from the 5–8 September, and there were plenty of ways for participants to network. PHOTO: Martyn Hicks

Uniting alumni at The EMBO Meeting

Connections Genevieve Almouzni and Nicolas Le Novère share their insights at alumni chapter meeting hosted in the UK.

2015

alumniconnections

3 September 2015 Moritz Gerstung

Welcome: Moritz Gerstung

Lab MattersPeople & Perspectives New group explores why patients with same cancer exhibit unique constellations of genetic mutations.

2015

lab-matterspeople-perspectives

26 August 2015 Hands-on sessions were a crucial part of the course. PHOTO: EMBL Photolab/Marietta Schupp

Super impressions

Connections "It's like living a review!" Participants of recent super-resolution microscopy course share their highlights

2015

connectionsevents

25 August 2015 Maja Köhn. PHOTO: EMBL Photolab/Marietta Schupp

Chemical bonds

Lab MattersPeople & Perspectives Maja Köhn’s lab is ideal to learn what life is like working at the interface of disciplines.

2015

lab-matterspeople-perspectives

24 August 2015

Celebrating excellence

People & Perspectives EMBL rewards the special work of alumni through the John Kendrew and Lennart Philipson awards.

2015

alumnipeople-perspectives

24 August 2015

Molecular momentum

People & Perspectives Andrew Miller, first head of EMBL Grenoble, reflects on four decades at the Outstation.

2015

alumnipeople-perspectives

24 August 2015 Janet Thornton. Photo: Robert Slowley

Transitions

Lab MattersPeople & Perspectives Janet Thornton reflects on her time as Director of one of Europe’s fastest growing research institutes.

2015

lab-matterspeople-perspectives

24 August 2015

Alumni board meeting

EMBL Announcements EMBL Alumni Association board meets for the last time in their current constellation.

2015

alumniembl-announcements

24 August 2015 Twelve members make up the EMBL Alumni Association board, taking up office in 2016

New board from 2016

EMBL Announcements Results are in for the EMBL Alumni Association board election – the board takes up office in 2016.

2015

alumniembl-announcements

24 August 2015 Researchers are developing a clearer picture of the molecular environment of our skin’s surface. IMAGE: Theodore Alexandrov

It’s the economy, stupid

Science & Technology Theodore Alexandrov is using mathematics to analyse the countless molecules produced by our cells.

2015

sciencescience-technology

24 August 2015

Cellular synergy

People & Perspectives Alumnus Thomas Vaccari reflects on the first joint symposium with EMBL Monterotondo, in Milan.

2015

eventspeople-perspectives

24 August 2015

Awards & Honours

EMBL AnnouncementsLab Matters EMBL scientists regularly receive prestigious awards – meet the latest honourees.

2015

embl-announcementslab-matters

24 August 2015 Fay Christodoulou, together with EMBL’s Vladimir Benes and Miroculus’ João Pereira de Lima

Decoding disease

Science & Technology Behind the scenes of start-up Miroculus, developing a non-invasive test for early-stage disease.

2015

alumniscience-technology

24 August 2015

An ocean odyssey

Science & Technology A journalist who spent six weeks aboard Tara reflects on the expedition’s extraordinary outcomes.

2015

sciencescience-technology

24 August 2015

Reviews: Summer reading

Lab Matters What’s on your Summer reading list? Here are some favourites of staff in the Lab.

2015

lab-matters

24 August 2015

Stick out your tongue!

People & Perspectives Alumnus Luis Bejarano asked Spanish students to stick out their tongues to analyse their microbiome.

2015

alumnipeople-perspectives

24 August 2015 Healthy Tasmanian devil in its natural habitat.

Branches: Sympathy for the devil

Lab Matters A contagious cancer threatens the Tasmanian devil – extract from Science in School journal.

2015

eventslab-matters

24 August 2015

EMBL Grenoble: Alumni stories

People & Perspectives Alumni Reuben Leberman, Jeremy Smith, Elena Seiradake, and Winfried Weissenhorn share their stories.

2015

alumnipeople-perspectives

24 August 2015 Maria Kamper at the her desk.

Pathways: Culture of care

ConnectionsLab Matters Maria Kamber, who heads the mouse facility, ensures “dignity, compassion and respect” for her charges.

2015

connectionslab-matters

20 August 2015

Life in 3D

Science & Technology EMBL scientists map ‘switches’ for distant control of gene expression.

2015

sciencescience-technology

20 August 2015

First, find your membrane

Science & Technology Collaboration between scientists reveals collaboration between lipids.

2015

sciencescience-technology

20 August 2015

The French connection

ConnectionsLab Matters EMBL Core Facilities collaborate with French research programme Signalife to revive training visit.

2015

connectionslab-matters

12 August 2015 Organiser Lars Steinmetz invites young researchers to the conference. PHOTO: EMBL Photolab/Claudiu Grozea

Make it personal

Connections Leading scientists will gather in Heidelberg this November to discuss the potential of personalised health.

2015

connectionsevents

10 August 2015 DREAM challenges

Life is but a DREAM

Science & Technology Crowd sourcing initiative to predict effects of toxic compounds: results of 2013 DREAM Challenge.

2015

sciencescience-technology

6 August 2015

Welcome: Theodore Alexandrov

People & Perspectives A mathematician who got ‘sucked in’ to biological problems, meet new team leader Theodore Alexandrov.

2015

people-perspectivesscience

4 August 2015 Healthy bone marrow (left) vs. bone marrow of leukaemia patient (right). IMAGE: MEDIZINISCHEN HOCHSCHULE HANNOVER

From patients to the lab (and back)

Science & Technology Multidisciplinary research provides clues to new treatments for deadly form of leukaemia in children

2015

sciencescience-technology

3 August 2015 To train T-cells to recognise our own body, cells in the thymus express different combinations of 'extra' genes. IMAGE: EMBL/P.RIEDINGER

Know your cells

Science & Technology How T-cells are trained on what not to kill

2015

sciencescience-technology

28 July 2015

Union makes success

ConnectionsLab Matters Molecular Medicine Partnership Unit (MMPU) with the University of Heidelberg, renewed until 2025.

2015

connectionslab-matters

28 July 2015

Political science

Lab MattersPeople & Perspectives Alumnus Damian Brunner revisits EMBL in a very special capacity, as Swiss delegate on EMBL’s Council.

2015

lab-matterspeople-perspectives

17 July 2015

Science of Spider-Man

Lab Matters Web of lies? Science Movie Night reveals science behind the most famous spider bite in film history.

2015

eventslab-matters

16 July 2015

Iron regulators join war on pathogens

Science & Technology Iron regulatory proteins play important role in combatting infection, protecting against Salmonella.

2015

sciencescience-technology

16 July 2015

Oskar’s structure revealed

Science & Technology 3D structure of Oskar protein gives first molecular insight into how it functions.

2015

sciencescience-technology

13 July 2015

EIPOD goes cubic

EMBL AnnouncementsLab Matters EI3POD: flagship interdisciplinary postdoc programme opens its doors to academia and industry.

2015

embl-announcementslab-matters

9 July 2015

The genome in the cloud

Science & Technology Jan Korbel and colleagues publish commentary on risks and rewards of genome cloud computing.

2015

sciencescience-technology

9 July 2015

DNA protection, inch by inch

Science & Technology European team identify mechanism for producing piRNAs that silence jumping genes in germline cells.

2015

sciencescience-technology

9 July 2015

The germ of a network biologist

Lab MattersPeople & Perspectives “Interactions: that’s what I like the most in biology” – meet Lukáš Janošík, EUCYS 2014 prize winner.

2015

lab-matterspeople-perspectives

9 July 2015 One from Many

One from Many

Lab MattersPeople & Perspectives Database administrator's photo essay reflects internationality and personality of the Genome Campus.

2015

lab-matterspeople-perspectives

3 July 2015

Sky’s the limit

Lab MattersScience & Technology Academic community clouds take cancer research towards a brighter future.

2015

lab-mattersscience-technology

30 June 2015 Timeline cake

Janet Thornton steps down

Lab Matters Staff gather to celebrate Janet Thorton's 14 years as Director of EMBL-EBI.

2015

lab-matters

10 June 2015 CERN openlab

EMBL-EBI joins CERN openlab

Lab Matters CERN openlab enters a new phase, expanding to include EMBL-EBI and other public research organisations.

2015

lab-matters

3 June 2015 What is ORCID? A sketchnote

Why you need an ORCID

Lab Matters Jenny Cham blogs about how ORCID helps distinguish her from all the other Jenny Chams in the world.

2015

lab-matters

2 June 2015 HMMER algorithm now available through EMBL-EBI

A powerful HMMER for data mining

Lab Matters HMMER – a fast, sensitive search tool – helps find sequence relationships deep in evolutionary time.

2015

lab-matters

27 May 2015

ELIXIR accelerates

Lab Matters ELIXIR receives major Horizon 2020 funding to ‘EXCELERATE' activities over the next four years.

2015

lab-matters

5 May 2015 PDBe launches a new, responsive, interactive website for structural biology

PDBe launches new website

Lab Matters In their quest to make structural biology more accessible, PDBe launches a new website.

2015

lab-matters

29 April 2015

History in the making

Lab Matters EMBL’s new Archivist will help chronicle the twists and turns, ups and downs of life at the Lab.

2015

lab-matters

29 April 2015

Pathways: In the prime of life

Lab Matters Karin Sasaki is helping bridge the gap between quantitative and life science at EMBL.

2015

lab-matters

11 March 2015

New Joint Directors of EMBL-EBI

Lab Matters Rolf Apweiler and Ewan Birney appointed Joint Directors of EMBL-EBI, as Janet Thornton steps down.

2015

lab-matters

8 March 2015 Sex in Science Award 2015

Supporting women in science

Lab Matters Wellcome Genome Campus gives first Best Practice Award for Supporting Women in Science.

2015

lab-matters

27 February 2015 Dr Jeffrey Barrett

Jeffrey Barrett to lead CTTV

Lab Matters Jeffrey Barrett appointed Director of CTTV, the GSK, EMBL-EBI and Sanger Institute partnership.

2015

lab-matters

28 January 2015 Dawn Johnson

Moving 20 Petabytes

Lab Matters A blog extract by Ewan Birney reflects on the challenges of moving a massive data-centre.

2015

lab-matters

26 January 2015

40 questions, answered

Lab Matters Find answers to 40 of your questions about life, the Lab and everything!

2015

lab-matters

26 January 2015

Awards & Honours

Lab Matters EMBL scientists regularly receive prestigious awards – meet the latest honourees.

2015

lab-matters

26 January 2015

Reviews: Illuminating stories

Lab Matters Which tales have illuminated something important to you? Staff from the Lab provide their favourite.

2015

lab-matters

26 January 2015

Meet the Dean

Lab Matters Meet Dean of Graduate Studies, Helke Hillebrand.

2015

lab-matters

23 January 2015 Silvia Rohr. PHOTO: EMBL PHOTOLAB/MARIETTA SCHUPP

Let there be light

Lab Matters PhD student Silvia Rohr on studying eyes – and talking about it for a general audience.

2015

lab-matters

20 January 2015 COMPARE project

Beyond COMPARE

Lab Matters New project aims to speed up detection and response to disease outbreaks using genome technology.

2015

lab-matters

16 January 2015

Christian Boulin Fellowship

Lab Matters New Christian Boulin Fellowship: 15 awards of up to €1500 for visitors to EMBL’s Core Facilities.

2015

lab-matters

8 January 2015 yourgenome.org

Relaunching YourGenome.org

Lab Matters EMBL-EBI supports relaunch of yourgenome.org, to bring genetics advances to a wider audience.

2015

lab-matters

15 December 2014

Luxembourg collaboration

Lab Matters Third round of calls for joint research projects between EMBL and Luxembourg in 2015

2014

lab-matters

11 December 2014

Dinner with a Nobel Laureate

Lab Matters The day EMBL Hamburg predocs and postdocs invited Nobel Prize Winner Ada Yonath to dinner.

2014

lab-matters

27 November 2014

Argentina: EMBL in action

Lab Matters Workshops, seminars and honorary lectures – strong start for EMBL’s newest associate member state.

2014

lab-matters

4 November 2014

Big (Protein) Data to Knowledge

Lab Matters 'Big Data to Knowledge' project by UCLA, Scripps and EMBL-EBI to transform protein data to knowledge.

2014

lab-matters

27 October 2014 The pollen trap used by Arkadiusz to collect pollen. PHOTO: ARKADIUSZ JANKIEWICZ

Looking for the beauty in science

Lab Matters How the author of a prize-winning project on bee travel ended up at a stem cells and cancer conference

2014

lab-matters

21 October 2014 Map of EMBL-EBI users

Job dispatched

Lab Matters How does EMBL-EBI run millions of jobs for its users while moving its two large data centres?

2014

lab-matters

17 October 2014 Nick Goldman and Charlotte Davies

Music of the spheres

Lab Matters Music, bubbles and DNA: a collaborative project brings artist and scientist together

2014

lab-matters

17 October 2014 Sarah Teichmann. PHOTO: UNIVERSITY OF CAMBRIDGE

Awards & Honours

Lab Matters EMBL scientists regularly receive prestigious awards - meet the latest honourees

2014

lab-matters

17 October 2014

100 different stories

Lab Matters Drumming, drama, dancing and discovery in a diary of art and science event, Roche Continents.

2014

lab-matters

17 October 2014

Reviews: Inspiring stories

Lab Matters Bibliophiles from the Lab pick out the stories that have inspired them at work and elsewhere.

2014

lab-matters

17 October 2014

Source of inspiration

Lab Matters PhD student Charles breeze found inspiration at this year's Lindau Nobel Laureate meeting.

2014

lab-matters

9 October 2014

Blog roundup: September

Lab Matters Pathfinding – poetic and practical – was a common theme in blogs from the EMBL network.

2014

lab-matters

8 September 2014

Obituary: Andrew D. Robertson

Lab Matters Andrew D Robertson, scientific coordinator of EICAT between 2011–12, died on 14 August 2014.

2014

lab-matters

5 September 2014

Scientists for a day

Lab Matters Tschira-Jugendakademie pupils get hands-on during day of DNA barcoding

2014

lab-matters

27 August 2014

Nordic networks

Lab Matters Nordic partners focus on "enhancing research enterprise", says Kjetil Taskén

2014

lab-matters

18 August 2014 Artist Stephen John Wright

Art inspired by data science

Lab Matters Artist Stephen Wright gifts artwork inspired by DNA storage research to EMBL-EBI.

2014

lab-matters

31 July 2014 Global Alliance for Genomics and Health

New genomics API

Lab Matters New genomics API allows researchers to share anonymised genetic data seamlessly across platforms.

2014

lab-matters

16 July 2014

Ask EMBL… anything!

Lab Matters Have a pressing question? EMBL experts are standing by to answer! Submit yours today.

2014

lab-matters

15 July 2014

Czech-ing out EMBL Council

Lab Matters Czech delegate Jana Bystřická represents EMBL's 21st member state at her first Council Meeting.

2014

lab-matters

1 July 2014 Vasily Sysoev

Back to school

Lab Matters School ambassadors show next generation that scientists are more ‘role model’ than ‘mad professor’

2014

lab-matters

1 July 2014 Matthias Wilmanns receives his membership certificate

Awards & Honours

Lab Matters EMBL scientists regularly receive prestigious awards - meet the latest honourees

2014

lab-matters

1 July 2014

In our DNA

Lab Matters To photographer Horst Hamann, it's the people, not the science, that make EMBL unique

2014

lab-matters

1 July 2014 Back to the Future, Part II (1989) PHOTO: UNIVERSAL STUDIOS

Reviews: Science on screen

Lab Matters Film enthusiasts from the Lab review their favourite science movies, one for each EMBL decade

2014

lab-matters

1 July 2014

Obituary: Christian Boulin

Lab Matters Christian Boulin, EMBL’s Director of Core Facilities and Services, died on 27 April 2014

2014

lab-matters

1 July 2014 Silke Schumacher

Still growing at 40

Lab Matters Busy times for EMBL keep Director of International Relations Silke Schumacher on the move

2014

lab-matters

1 July 2014 Illustration: Aad Goudappel, Rotterdam

Five for the future

Lab Matters Scientists from EMBL's five sites reflect on the opportunities and challenges that might lie ahead

2014

lab-matters

1 July 2014 Question mark

Q&A

Lab Matters Which scientific breakthroughs would EMBL scientists most like to see in the next 40 years?

2014

lab-matters

25 June 2014

On target

ConnectionsLab Matters A new EMBL-EBI biomedical initiative works to determine the best target proteins for new drugs.

2014

connectionslab-matters

25 June 2014

Chain reactions

Science & Technology Scientists determine the structure of auxin response factors: daisy-chains that regulate gene expression

2014

sciencescience-technology

25 June 2014

Taken out of context

Science & Technology Enabling neighbours: intact genes can cause cancer when placed near "enhancing" regions of DNA

2014

sciencescience-technology

21 June 2014 Ocean Sampling Day 2014

Capturing marine biodiversity

Science & Technology Data from first ever worldwide Ocean Sampling Day will be shared via EMBL-EBI resources this autumn.

2014

sciencescience-technology

10 June 2014

Czech Republic becomes EMBL’s 21st member state

Connections Forty years after its foundation, EMBL announces its 21st member state: the Czech Republic. Building on a successful bilateral relationship, the Czech Republic’s membership grants Czech scientists access to EMBL’s state-of-the-art instruments, facilities and world-class training…

2014

connectionsevents

25 May 2014

Insights into genetics of cleft lip

Science & Technology How a DNA stretch influences face formation and contributes to common congenital malformations

2014

sciencescience-technology

18 May 2014

First, catch your DNA

Science & Technology DNA-coralling protein complex in an unexpected bind

2014

sciencescience-technology

9 May 2014

How immune cells use steroids

Science & Technology Genome Campus researchers discover that some immune cells turn themselves off by producing a steroid.

2014

sciencescience-technology

8 May 2014 Microscopy image

Remodelling the cell

Science & Technology The balance behind membrane changes that turn one cell into 6000 as a fruit fly embryo develops

2014

sciencescience-technology

24 April 2014

Tsetse fly genome sequenced

Science & Technology Tsetse fly genome sequenced; scientists hope to find new ways to control sleeping sickness.

2014

sciencescience-technology

22 April 2014

Argentina joins EMBL as associate member state

Connections At a signing ceremony today, Argentina joins the European Molecular Biology Laboratory (EMBL) as an associate member state. The move strengthens the ties between the European and Latin American life science communities. It grants Argentinian scientists access to EMBL’s world-class facilities and…

2014

connectionsevents

27 March 2014

Where do you start when developing a new medicine?

ConnectionsLab Matters A pioneering public-private research initiative between GSK, the European Bioinformatics Institute (EMBL-EBI) and the Wellcome Trust Sanger Institute is to harness the power of ‘big data’ and genome sequencing to improve the success rate for discovering new medicines. The new Centre for…

2014

connectionslab-matters

7 March 2014

Slovak Republic becomes EMBL Prospect Member State

Connections The European Molecular Biology Laboratory (EMBL) welcomes the Slovak Republic as the first country to join its new Prospect Member scheme. In a Statement of Intent signed last month, the Slovak Republic and EMBL agree to explore the possibilities for long-term cooperation, with a view to the…

2014

connectionsevents

24 February 2014

Pan-European imaging infrastructure gains momentum

ConnectionsLab Matters Europe is uniting to make state-of-the-art imaging technologies accessible to biomedical researchers throughout the continent in a concerted manner. The European Molecular Biology Laboratory (EMBL) and seven countries (Belgium, Finland, Italy, Poland, Slovakia, the Netherlands, the United Kingdom)…

2014

connectionslab-matters

2 February 2014

Making your brain social

Science & Technology In many people with autism and other neurodevelopmental disorders, different parts of the brain don’t talk to each other very well. Scientists have now identified, for the first time, a way in which this decreased functional connectivity can come about. In a study published online today…

2014

sciencescience-technology

10 November 2013

What are you scared of?

Science & Technology What do bullies and sex have in common? Based on work by scientists at the European Molecular Biology Laboratory (EMBL) in Monterotondo, Italy, it seems that the same part of the brain reacts to both. In a study published today in Nature Neuroscience, the researchers found that – at least in…

2013

sciencescience-technology

23 October 2013

Bigger, better, faster

Science & Technology The molecular machine that makes essential components of ribosomes – the cell’s protein factories – is like a Swiss-army knife, researchers at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, and the Centro de Investigaciones Biológicas in Madrid, Spain, have found.…

2013

sciencescience-technology

13 October 2013

Choreographed origami

Science & Technology An important step in building ribosomes – the cell’s protein factories – is like a strictly choreographed dance, scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have discovered. To build these factories, other ‘machines’ inside the cell have to…

2013

sciencescience-technology

25 September 2013

Without a trace

Science & Technology Migrating cells, it seems, cover their tracks not for fear of being followed, but to keep moving forward. Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have now shown that cells in a zebrafish embryo determine which direction they move in by effectively…

2013

sciencescience-technology

12 September 2013

Potential new drug target for cystic fibrosis

Science & Technology Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg and Regensburg University, both in Germany, and the University of Lisboa, in Portugal, have discovered a promising potential drug target for cystic fibrosis. Their work, published online today in Cell, also uncovers a…

2013

sciencescience-technology

11 August 2013

From fireman to arsonist

Science & Technology Like a fireman who becomes an arsonist, a protein that prevents cells becoming cancerous can also cause tumours, scientists at the European Molecular Biology Laboratory (EMBL) in Grenoble, France, have discovered. The finding, published today in Nature Structural and Molecular Biology, stems…

2013

sciencescience-technology

11 August 2013

PS: It’s not cholesterol

Science & Technology How our body processes cholesterol has a well-known impact on our health, but it turns out that another ‘fat molecule’ – or lipid – may be at the heart of some diseases which were thought to involve cholesterol. A group of proteins linked to conditions such as metabolic syndrome and some…

2013

sciencescience-technology

7 August 2013

Cells eat themselves into shape

Science & Technology The process cells use to ‘swallow’ up nutrients, hormones and other signals from their environment – called endocytosis – can play a crucial role in shaping the cells themselves, scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have found. The study,…

2013

sciencescience-technology

11 July 2013

How to build your gate

Science & Technology It’s a parent’s nightmare: opening a Lego set and being faced with 500 pieces, but no instructions on how to assemble them into the majestic castle shown on the box. Thanks to a new approach by scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany,…

2013

sciencescience-technology

14 May 2013

But what does it do?

Science & Technology Although we know the tool’s general purpose, it can sometimes be difficult to tell if a specific pair of precision tweezers belongs to a surgeon or a master jeweller. It is now easier to solve similar conundrums about a type of protein that allows cells to react to their environment, thanks to…

2013

sciencescience-technology

24 April 2013

Pushing the boundaries of transcription

Science & Technology Like musicians in an orchestra who have the same musical score but start and finish playing at different intervals, cells with the same genes start and finish transcribing them at different points in the genome. For the first time, researchers at EMBL have described the striking diversity of…

2013

sciencescience-technology

27 March 2013

Become a member of Euro-BioImaging

ConnectionsLab Matters Euro-BioImaging, the pan-European open access research infrastructure for biological and medical imaging technologies, invites leading European imaging facilities to submit proposals to participate. Applications to become a Euro-BioImaging node will be reviewed by a board of independent…

2013

connectionslab-matters

11 March 2013

Havoc in biology’s most-used human cell line

Science & Technology HeLa cells are the world’s most commonly used human cell lines, and have served as a standard for understanding many fundamental biological processes. In a study published today in G3: Genes, Genomes and Genetics online, scientists at the European Molecular Biology Laboratory in…

2013

sciencescience-technology

5 March 2013

Denmark joins the Nordic EMBL Partnership for Molecular Medicine

ConnectionsLab Matters Today, the Nordic EMBL Partnership for Molecular Medicine celebrates two important milestones: the renewal of the partnership agreement for an extended period of 10 years, and the expansion of the Nordic EMBL network with the official opening of the Danish Research Institute of Translational…

2013

connectionslab-matters

28 February 2013

DNA’s twisted communication

Science & Technology During embryo development, genes are dynamically, and very precisely, switched on and off to confer different properties to different cells and build a well-proportioned and healthy animal. Fgf8 is one of the key genes in this process, controlling in particular the growth of the limbs and…

2013

sciencescience-technology

28 February 2013

Zeroing in on heart disease

Science & Technology Studies screening the genome of hundreds of thousands of individuals (known as Genome-wide association studies or GWAS) have linked more than 100 regions in the genome to the risk of developing cardiovascular disease. Researchers from the European Molecular Biology Laboratory (EMBL) and the…

2013

sciencescience-technology

11 February 2013

One disease, two mechanisms

Science & Technology While prostate cancer is the most common cancer in elderly Western men it also, but more rarely, strikes patients aged between 35 and 50. Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, in collaboration with several other research teams in Germany*, have…

2013

sciencescience-technology

4 February 2013

Learning from the linker

Science & Technology Mature cells can be reprogrammed to pluripotency and thus regain the ability to divide and differentiate into specialized cell types. Although these so-called induced pluripotent stem cells (iPS cells) represent a milestone in stem cell research, many of the biochemical processes that underlie…

2013

sciencescience-technology

31 January 2013

The mutation police

Science & Technology Scientists at the EMBL-European Bioinformatics Institute (EMBL-EBI) and the MRC Laboratory of Molecular Biology in the UK have discovered how our genome keeps the effects of mutations in check. The discovery, published in the journal Cell, will help in the study of diseases such as cancer and…

2013

sciencescience-technology

23 January 2013

EMBL-EBI researchers make DNA storage a reality

Science & Technology Researchers at the EMBL-European Bioinformatics Institute (EMBL-EBI) have created a way to store data in the form of DNA – a material that lasts for tens of thousands of years. The new method, published today in the journal Nature, makes it possible to store at least 100 million hours of…

2013

sciencescience-technology

17 January 2013

The cell that isn’t

Science & Technology This may look like yet another video of a dividing cell, but there’s a catch. You are looking at chromosomes (red) being pulled apart by the mitotic spindle (green), but it’s not a cell, because there’s no cell membrane. Like a child sucking an egg out of its shell, Ivo Telley from the…

2013

sciencescience-technology

6 January 2013

Protein production: going viral

Science & Technology A research team of scientists from EMBL Grenoble and the IGBMC in Strasbourg, France, have, for the first time, described in molecular detail the architecture of the central scaffold of TFIID: the human protein complex essential for transcription from DNA to mRNA. The study, published today…

2013

sciencescience-technology

19 December 2012

Sync to grow

Science & Technology Gene expression wave in the lower part of the future vertebrae column of a mammalian embryo. As the wave goes forward, new pre-vertebrae are formed and the future vertebrae column elongates. (Image and video credit: Nature) In a nutshell: The size of pre-vertebrae in a mammalian embryo is…

2012

sciencescience-technology

5 December 2012

My microbes

Science & Technology In a nutshell : The gut metagenome is the collection of all the genomes of all the microbes  in the human intestinal tract : it is specific to each human, like a second genetic signature At least in healthy humans, this personal metagenome is stable over time The gut metagenome is…

2012

sciencescience-technology

31 October 2012

Spot the difference

Science & Technology In a nutshell: 1st map combining human genetic variation at different scales – from single letters to large chunks Based on genomes of 1092 healthy people from Europe, the Americas and East Asia Could help identify genetic causes of disease, rather than just links Data made freely available in…

2012

sciencescience-technology

27 September 2012 Diagram showing looping DNA

Loop the loop, DNA style

Science & Technology In a nutshell: Looping and unlooping DNA adjusts readout from gene and spread of regulation throughout the genome When a gene forms a loop, its output increases, as the transcription machinery that reads it is trapped into moving only along that gene When the gene loop is undone, transcription…

2012

sciencescience-technology

23 September 2012 Cartoon showing cell communication

Cellular eavesdropping made easy

Science & Technology In a nutshell: New method allows precise analysis of proteins released by cells over time (distinguishes them from proteins in the cells’ culture serum) Advantages: cells don’t have to be starved: avoids bias and allows more cell types to be studied; can follow fast reactions like immune…

2012

sciencescience-technology

5 September 2012 ENCODE researchers found that most of our DNA has a function: controlling when and where genes are turned on and off.

Fast forward for biomedical research

Science & Technology Today, an international team of researchers reveal that much of what has been called ‘junk DNA’ in the human genome is actually a massive control panel with millions of switches regulating the activity of our genes. Without these switches, genes would not work – and mutations in these regions…

2012

sciencescience-technology

2 August 2012 Different inhibitors (yellow, grey) fill the cave-like active site of the cap-snatching protein (the endonuclease, in green) differently, even though they all bind to the active site’s two metal ions (magenta).

Catching the cap-snatcher

Science & Technology Researchers at the European Molecular Biology Laboratory (EMBL) in Grenoble, France, have determined the detailed 3-dimensional structure of part of the flu virus’ RNA polymerase, an enzyme that is crucial for influenza virus replication. This important finding is published today in PLoS…

2012

sciencescience-technology

19 July 2012 The female (left) fruit fly, Drosophila melanogaster, is larger than the male (right). Image credit: EMBL.

Of flies and men

Science & Technology What do you get when you dissect 10 000 fruit-fly larvae? A team of researchers led by the EMBL- European Bioinformatics Institute (EMBL-EBI) in the UK and the Max Planck Institute of Immunobiology and Epigenetics (MPI) in Germany has discovered a way in which cells can adjust the activity of many…

2012

sciencescience-technology

12 July 2012

Italy pledges to be part of ELIXIR research infrastructure

Connections Italy has pledged to participate in ELIXIR, a major undertaking to safeguard the results of life science research in Europe. With one of Europe’s larger economies now demonstrating its commitment to ELIXIR, this burgeoning research infrastructure is well placed to continue its excellent progress.…

2012

connectionsscience

5 July 2012

Stop and go

Science & Technology A traffic policeman standing at a busy intersection directing the flow of vehicles may be a rare sight these days, but a similar scene appears to still frequently play out in our cells. A protein called Lem4 directs a crucial step of cell division by preventing the progress of one molecule while…

2012

sciencescience-technology

21 June 2012

Flu fighters

Science & Technology Savira pharmaceuticals GmbH, a spin-off of the European Molecular Biology Laboratory (EMBL) based in Vienna, Austria, has signed a collaboration and license agreement with Roche, thus further strengthening the links between fundamental research and major pharmaceutical development companies. This…

2012

sciencescience-technology

3 June 2012

Shape-shifting shell

Science & Technology As a retrovirus matures, the two parts of its shell protein (red and blue or yellow and blue) dramatically rearrange themselves, twisting and moving away from each other. (Credit: EMBL/T.Bharat) Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have for the…

2012

sciencescience-technology

3 June 2012

Video Release: Filming life in the fast lane

Science & Technology “This video shows a fruit fly embryo from when it was about two-and-a-half hours old until it walked away from the microscope as a larva, 20 hours later,” says Lars Hufnagel, from the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany. “It shows all the hallmarks of fruit fly…

2012

sciencescience-technology

3 June 2012 Silenced genes in a cell

Export extravaganza

Science & Technology Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have conducted the first comprehensive census of human cells’ export workers. In a study published online today in Nature Cell Biology, they found an unexpected variety of genes involved in transporting…

2012

sciencescience-technology

31 May 2012 Word cloud of proteins

The cell’s ‘New World’

Science & Technology In one of the most famous faux pas of exploration, Columbus set sail for India and instead ‘discovered’ America. Similarly, when scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, set out to find enzymes – the proteins that carry out chemical…

2012

sciencescience-technology

24 May 2012 Cell vesicles serve as transport pods to ferry cargo around the cell.

Picture Release: More than meets the eye

Science & Technology These spheres may look almost identical, but subtle differences between them revealed a molecular version of the robots from Transformers. Each sphere is a vesicle, a pod that cells use to transport materials between different compartments. The images, produced by Marco Faini from John…

2012

picture-of-the-weekscience-technology

24 May 2012 Microglial cells

Locating ground zero

Science & Technology Like emergency workers rushing to a disaster scene, cells called microglia speed to places where the brain has been injured, to contain the damage by ‘eating up’ any cellular debris and dead or dying neurons. Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany,…

2012

sciencescience-technology

22 April 2012 Abstract image showing DNA code

A matter of priorities

Science & Technology Just as banks store away only the most valuable possessions in the most secure safes, cells prioritise which genes they guard most closely, researchers at the European Molecular Biology Laboratory’s European Bioinformatics Institute (EMBL-EBI) have found. The study, published online today…

2012

sciencescience-technology

20 March 2012 A slice through the tails of mouse sperm.

Picture release: Spring tails

Science & Technology As spring arrives, flowers seem to bloom everywhere – even under the microscopes at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany. But the ‘flowers’ in this picture actually help an animal, not a plant, to pass on its genes. The image, which has been false-coloured…

2012

picture-of-the-weekscience-technology

18 March 2012

Need for speed

Science & Technology Like any law-abiding train passenger, a molecule called oskar RNA carries a stamped ticket detailing its destination and form of transport, scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have found. They show that for this molecule, moving in the…

2012

sciencescience-technology

1 March 2012

Flying high in Europe

Science & Technology Today a consortium of leading IT providers and three of Europe’s biggest research centres (CERN, EMBL and ESA) announced a partnership to launch a European cloud computing platform. ‘Helix Nebula ‐ the Science Cloud’, will support the massive IT requirements of European…

2012

sciencescience-technology

28 February 2012

Making the most of what you have

Science & Technology The bacterium Mycoplasma pneumoniae, which causes atypical pneumonia, is helping scientists uncover how cells make the most of limited resources. By measuring all the proteins this bacterium produces, scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, and…

2012

sciencescience-technology

23 February 2012

New distributed research infrastructure for structural biology

Science & Technology Breakthroughs in biomedical science are a step closer today, with the launch of a new distributed research infrastructure for the science of structural biology: Instruct. The launch of Instruct will give academic and commercial scientists across Europe access to a full portfolio of integrated…

2012

sciencescience-technology

19 February 2012 Diagram of the Elongator protein

Trapped in a ring

Science & Technology In fairy tales, magic rings endow their owners with special abilities: the ring makes the wearer invisible, fulfils his wishes, or otherwise helps the hero on the path to his destiny.  Similarly, a ring-like structure found in a protein complex called ‘Elongator’ has led researchers at the…

2012

sciencescience-technology

14 February 2012

Stretching helices help keep muscles together

Science & Technology Myomesin stretching to 2.5 times its length. Credit: EMBL/Wilmanns. In this video, a protein called myomesin does its impression of Mr. Fantastic, the leader of the Fantastic Four of comic book fame, who performed incredible feats by stretching his body. Scientists at the European Molecular Biology…

2012

sciencescience-technology

2 February 2012 Fruit fly embryo showing the cells that will become the gut and heart

Collective action

Science & Technology If you wanted to draw your family tree, you could start by searching for people who share your surname. Cells, of course, don’t have surnames, but scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have found that genetic switches called enhancers, and the…

2012

sciencescience-technology

19 January 2012 Artist's impression of a chromosome exploding

Rigged to explode?

Science & Technology An inherited mutation in a gene known as the guardian of the genome is likely the link between exploding chromosomes and some particularly aggressive types of cancer, scientists at the European Molecular Biology Laboratory (EMBL), the German Cancer Research Centre (DKFZ) and the University…

2012

sciencescience-technology

12 January 2012

Evolution by ‘copy-paste’

Science & Technology A team of geneticists and computational biologists at the European Molecular Biology Laboratory’s European Bioinformatics Institute (EMBL-EBI), the Wellcome Trust Sanger Institute and Cancer Research UK reveal how an ancient mechanism is involved in gene control and continues to drive genome…

2012

sciencescience-technology

8 January 2012 Diagram of chromatin enhancers

Tracking genes’ remote controls

Science & Technology As an embryo develops, different genes are turned on in different cells, to form muscles, neurons and other bodily parts. Inside each cell’s nucleus, genetic sequences known as enhancers act like remote controls, switching genes on and off. Scientists at the European Molecular Biology Laboratory…

2012

sciencescience-technology

14 September 2011

Five countries and EMBL sign Memorandum of Understanding to make ELIXIR a reality

Lab Matters Today marks an important step for ELIXIR, Europe’s emerging research infrastructure for life-science information, as five countries plus the European Molecular Biology Laboratory (EMBL) have signed a Memorandum of Understanding to catalyse the implementation and construction of ELIXIR. The…

2011

lab-matters

5 July 2011 Lennart Philipson, 1929-2011.

Obituary – Lennart Philipson

Lab Matters Lennart Philipson, who served as EMBL’s second Director General, has passed away. Lennart headed EMBL for over a decade between 1982-93, a crucial time for molecular biology when different scientific disciplines in the life sciences were becoming increasingly interlinked. He reorganised the…

2011

lab-matters

4 March 2011 Máire Geoghegan-Quinn, European Commissioner for Research, Innovation and Science, and Iain Mattaj, Director-General of EMBL, signing the Memorandum of Understanding.

European Commission and EMBL renew cooperation

Lab Matters In a Memorandum of Understanding signed today, the European Commission (EC) and the European Molecular Biology Laboratory (EMBL) formalise their desire to maintain and further develop their cooperation. “I am delighted to sign the renewed and strengthened Memorandum of Understanding between the…

2011

lab-matters

8 November 2010 Signing the declaration of accession to the EIROforum: Massimo Altarelli, Chairman of the XFEL Management Board (left) and Francesco Romanelli, Chairman of the EIROforum (right). In the back (left to right): Francesco Sette (ESRF), Felicitas Pauss (CERN), Iain Mattaj (EMBL), Richard Wagner (ILL), Rowena Sirey (ESO) and David Southwood (ESA)

European XFEL joins EIROforum

Lab Matters At the Autumn 2010Council meeting of the EIROforum, a partnership of seven European intergovernmental research organisations with large research infrastructures, the Directors General unanimously accepted the European X-Ray Free-Electron Laser Facility (European XFEL), based in Hamburg, Germany, to…

2010

lab-matters

9 March 2010 The new EMBL Advanced Training Centre in Heidelberg, Germany. PHOTO: Hugo Nevers/EMBL

New training and conference centre for the life sciences at EMBL in Heidelberg

Lab Matters Today, the German Minister for Education and Research, Annette Schavan, officially opens the new training and conference centre for the life sciences on the campus of the European Molecular Biology Laboratory (EMBL) in Heidelberg. “This new centre in Heidelberg will form a central European…

2010

lab-matters

22 June 2009 EMBL Rome

European centre of excellence for mouse biology celebrates its 10th anniversary

Lab Matters Mice are one of biology’s most important model organisms, because 98% of their genes and many of their traits and diseases are similar to ours. Researchers at the Mouse Biology Unit of the European Molecular Biology Laboratory (EMBL) take advantage of these similarities and use mice to study…

2009

lab-matters

12 December 2008

Leica Microsystems to become Founder Partner of EMBL Advanced Training Centre

Lab Matters Microscope designer Leica Microsystems and the European Molecular Biology Laboratory (EMBL) signed a corporate partnership agreement today whereby Leica Microsystems becomes a founder partner of the EMBL Advanced Training Centre scheduled to be completed in September 2009. Besides its financial…

2008

lab-matters

16 October 2008

Researchers establish international human microbiome consortium

Lab Matters Today at a meeting organised by the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, scientists from around the globe announced the formation of the International Human Microbiome Consortium (IHMC), an effort that will enable researchers to characterise the relationship of the…

2008

lab-matters

23 July 2008

Open access to large-scale drug discovery data

Lab Matters The Wellcome Trust has awarded £4.7 million (€5.8 million) to EMBL’s European Bioinformatics Institute (EMBL-EBI) to support the transfer of a large collection of information on the properties and activities of drugs and a large set of drug-like small molecules from the publicly listed…

2008

lab-matters

28 May 2008

Securing the future of Europe’s biological data resources

Lab Matters In a contract signed today, the European Commission has awarded €4.5 million to a pan-European consortium to decide upon the best way to unite Europe’s biological data resources into a sustainable, integrative bioinformatics network for the life sciences. The European Life-science…

2008

lab-matters

22 January 2008

International consortium announces the 1000 Genomes Project

Lab Matters Drawing on the expertise of multi-disciplinary research teams, the map developed by the 1000 Genomes Project will provide a view of biomedically relevant DNA variations at a resolution unmatched by current resources. The European Bioinformatics Institute (EBI), working with long-term collaborator…

2008

lab-matters

11 December 2007

ArrayExpress database doubles in size to 100,000 hybridisations

Lab Matters ArrayExpress, the publicly available database of transcriptomics data at the European Molecular Biology Laboratory’s European Bioinformatics Institute (EMBL-EBI), has doubled in size in 2007, reaching the 100,000-hybridisation milestone. The database now holds snapshots of gene expression…

2007

lab-matters

12 November 2007

Luxembourg joins EMBL

Lab Matters Today, the European Molecular Biology Laboratory (EMBL) announces Luxembourg as the new member of its international community. Accepted by EMBL’s council and ratified by the parliament of Luxembourg, the Grand-Duchy has officially joined the institute as the 20th member state. “EMBL is…

2007

lab-matters

23 October 2007

The East Wing and a new dawn for the EMBL-EBI

Lab Matters The European Molecular Biology Laboratory’s European Bioinformatics Institute (EMBL-EBI) officially opens its new East Wing today with a reception for prominent guests. The East Wing will be jointly opened by Ian Pearson, Minister of State for Science and Innovation, UK, and Robert-Jan Smits,…

2007

lab-matters

3 October 2007

EMBL reaches north

Lab Matters Today the European Molecular Biology Laboratory (EMBL), the University of Helsinki, Finland, the University of Oslo, Norway, and Umeå University, Sweden, officially launch their new Nordic EMBL Partnership for Molecular Medicine. The agreement will encourage scientific exchange and collaborations…

2007

lab-matters

28 August 2007

Minimum Information Standards ─ all for one and one for all

Lab Matters Three papers published by EMBL scientists and their collaborators will make it much easier to share and compare information from large-scale proteomics data. The papers are published in Nature Biotechnology on 8 and 26 August. As the quantity of available biological information and the use of…

2007

lab-matters

11 July 2007

EMBL expands to Australia

Lab Matters Today, delegates representing the 19 member states of the European Molecular Biology Laboratory (EMBL) offered Australia associate membership in EMBL’s international community. The membership is planned to start officially in January 2008 and will initially last for seven years. “EMBL…

2007

lab-matters

22 May 2007

The first public nucleotide sequence database turns 25

Lab Matters It was the world’s earliest public database of DNA and RNA sequences and remains Europe’s primary nucleotide sequence resource. The database is maintained by EMBL’s European Bioinformatics Institute in Hinxton (UK) in collaboration with its US and Japanese counterparts GenBank and…

2007

lab-matters

8 January 2007

UK PubMed Central launched

Lab Matters From today scientists will be able to access a vast collection of biomedical research and to submit their own published results for inclusion in a new online resource. Based on a model currently used by the US National Institute of Health, UK PubMed Central (UKPMC) will provide free access to a…

2007

lab-matters

14 December 2006

Magna Carta for Researchers

Lab Matters Today, Janez Potočnik, European Commissioner for Science and Research, received a statement of support for the European Charter for Researchers and the Code of Conduct for the Recruitment of Researchers from EIROforum. “The EIROforum partners warmly welcome this valuable initiative by…

2006

lab-matters

11 December 2006

Better, faster, easier

Lab Matters Today the European Molecular Biology Laboratory’s European Bioinformatics Institute (EMBL-EBI) launches its new, faster and easier website with an exhaustive search engine at its centre. The web interface has been streamlined on the basis of user feedback from a recent extensive…

2006

lab-matters

27 November 2006

CiteXplore

Lab Matters Today the European Molecular Biology Laboratory’s European Bioinformatics Institute (EMBL-EBI) launches CiteXplore, a new freely accessible literature resource service. Biological researchers require two crucial sources of information: scientific literature published in peerreviewed…

2006

lab-matters

6 October 2006

Giving European science a headstart through training

Lab Matters Today, the German Minister for Education and Research, Annette Schavan, breaks ground for the new training and conference centre for the life sciences that will be built on the EMBL campus in Heidelberg. The German Ministry for Education and Research (BMBF), the Klaus Tschira…

2006

lab-matters

7 September 2006

New EMBL/CRG Research Unit for Systems Biology launched today

Lab Matters Today the European Molecular Biology Laboratory (EMBL), the Centre for Genomic Regulation (CRG) and the Spanish Ministry for Education and Science (MEC) officially launch their new joint EMBL/CRG Research Unit in Systems Biology on the campus of the Barcelona Biomedical Research Park. The Spanish…

2006

lab-matters

9 August 2006

EMBL scientists found start-up company to develop anti-cancer drugs

Lab Matters Today EMBL scientists, EMBL’s commercial affiliate, EMBL Enterprise Management Technology Transfer GmbH (EMBLEM) and EMBL’s venture vehicle, EMBL Ventures GmbH, announce the foundation of Elara Pharmaceuticals GmbH, a start-up company that will translate basic research findings into new…

2006

lab-matters

31 July 2006

EMBL-EBI and collaborators win bid to run UK PubMed Central

Lab Matters Scientists will be able to access a vast collection of biomedical research at the touch of a button thanks to a major new initiative that aims to promote the free transfer of ideas in a bid to speed up scientific discovery. Based on a model currently used in the United States, UK PubMed Central…

2006

lab-matters

11 July 2006

Mapping the protein world

Lab Matters In the early days of X-ray crystallography obtaining a three-dimensional model of a protein required wire models, screws, bolts and years of tedious calculations by hand. Today macromolecular models are built by computers – thanks to sophisticated software and in particular a package called…

2006

lab-matters

29 June 2006

Croatia becomes EMBL’s 19th Member State

Lab Matters Croatia has officially joined the European Molecular Biology Laboratory (EMBL) as the organisation’s 19th Member State. The Croatian parliament ratified its membership after EMBL’s council had accepted the country’s application. “Joining EMBL is a very important step…

2006

lab-matters

25 April 2006

A brighter future for Europe’s favourite molecular biology software package

Lab Matters EMBOSS, the European Molecular Biology Open Software Suite, has received a vital funding boost from the UK Biotechnology and Biological Sciences Research Council (BBSRC) that will guarantee its continued maintenance under an open source license for the next three years. This ends two years of…

2006

lab-matters

10 April 2006

Getting to the heart of cardiovascular diseases

Lab Matters Today three research organisations announce the merging of their expertise to fight cardiovascular diseases, which are among the most common health problems and causes of death in the world. The Magdi Yacoub Institute (MYI) at the UK’s Harefield Heart Science Centre, Imperial College London,…

2006

lab-matters

28 March 2006

Bringing science out of the lab into the classroom

Lab Matters Science is moving more rapidly than ever; one groundbreaking discovery chases the next at an incredible speed. School teachers have trouble keeping up with the pace, and many pupils call science classes “boring”. Today, Europe’s major research organisations launch Science in…

2006

lab-matters

10 January 2006

A major European Centre for Structural Biology inaugurated in Grenoble

Lab Matters On Friday, 13 January 2006, the new Carl-Ivar Brändén Building (CIBB) will be inaugurated on the Polygone Scientifique Campus in Grenoble, France. The CIBB will be operated as a collaboration between major international and national partners based in Grenoble and is a further step in the…

2006

lab-matters

6 December 2005

Setting the standard for computer models of life

Lab Matters In the December 6 issue of Nature Biotechnology, scientists from 14 different organizations around the world, including the EMBL-European Bioinformatics Institute, propose a new quality standard for biochemical models. MIRIAM [for Minimum information requested in the annotation of biochemical…

2005

lab-matters

31 October 2005

ENFIN! Computational systems biology comes to a lab bench near you

Lab Matters The Commission of the European Union has awarded EUR 9 million over five years for a new Network of Excellence that will make computational systems biology accessible to bench scientists throughout Europe and beyond. ENFIN, which stands for ‘Experimental Network for Functional…

2005

lab-matters

29 August 2005

EBI and Ghent University launch PRIDE

Lab Matters The European Bioinformatics Institute and Flanders Interuniversity Institute for Biotechnology (VIB) – Ghent University have launched the PRoteomics IDEntifications database (PRIDE). PRIDE allows researchers who work in the field of proteomics – the large-scale study of proteins – to…

2005

lab-matters

22 August 2005

Public collections of DNA and RNA sequence reach 100 gigabases

Lab Matters The world’s three leading public repositories for DNA and RNA sequence information have reached 100 gigabases (100,000,000,000 bases; the ‘letters’ of the genetic code) of sequence. Thanks to their data exchange policy, which has paved the way for the global exchange of many types…

2005

lab-matters

18 July 2005

Molecular Medicine Partnership Unit initiates second phase

Lab Matters The first rate research from the Molecular Medicine Partnership Unit (MMPU) is now set to continue for the long-term. The European Molecular Biology Laboratory (EMBL) and the Medical Faculty of University of Heidelberg, who formed the joint venture in 2002, have announced their plans to initiate a…

2005

lab-matters

12 July 2005

Hunt for human genes involved in cell division under way

Lab Matters A systematic search through human genes has begun at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany. Working within the MitoCheck consortium that includes 10 other institutes throughout Europe, the EMBL scientists will silence all human genes, one-by-one, to find those…

2005

lab-matters

1 May 2005

EMBL’s fourth Director-General, Dr Iain Mattaj, takes office

Lab Matters Dr. Iain Mattaj today took over the leadership of the European Molecular Biology Laboratory [EMBL], a prominent basic research and training institute with laboratories in France, Germany, Italy and the UK. “The pace of progress in the life sciences is remarkable. I see my job as ensuring that…

2005

lab-matters

31 March 2005

The transparent organism

Lab Matters A novel high-tech microscope will be brought to the marketplace, giving laboratories everywhere fascinating new insights into living organisms. EMBLEM Technology Transfer GmbH (EMBLEM), the commercial entity of the European Molecular Biology Laboratory (EMBL), announced today that it has signed a…

2005

lab-matters

28 February 2005

Double recognition of EBI scientists by the ISCB

Lab Matters The International Society for Computational Biology has named two scientists from the European Bioinformatics Institute as the winners of its awards for 2005. Janet Thornton wins the Senior Scientist Accomplishment Award while the Overton Prize goes to Ewan Birney. Thomas Lengauer, the ISCB’s…

2005

lab-matters

3 February 2005

Biology in four dimensions

Science & Technology Most things that happen in the cell are the work of ‘molecular machines’ – complexes of proteins that carry out important cellular functions. Until now, scientists didn’t have a clear idea of when proteins form these machines – are these complexes pre-fabricated or put…

2005

sciencescience-technology

1 February 2005

European bioinformatics grid receives 8 million Euro

Lab Matters The Commission of the European Union has awarded 8.3 million Euro to a pan-European task force who will improve access to biological information for scientists throughout and beyond Europe. The EMBRACE Network of Excellence, which encompasses computational biologists from 17 institutes in 11…

2005

lab-matters

25 January 2005

How do cells travel through our bodies?

Science & Technology One of the most basic yet least understood processes in our bodies is how cells crawl along tissues. This behavior is essential to the formation of an embryo and other processes, but it must be tightly controlled. A disturbance can lead to the spread of cancer cells or diseases like Spina…

2005

sciencescience-technology

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