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Science

Cell division

Tracing the origins of cells

Researchers from the Sharpe group at EMBL Barcelona have published a method to track the developmental history of a cell using the gene editing tool CRISPR–Cas9, but without the need to create transgenic organisms.…

By Fabian Oswald

Science

Close-up photograph of servers at EMBL Heidelberg's data centre.

Understanding the role of our genes in SARS-CoV-2 infections

EMBL scientists will contribute to the new German COVID-19 OMICS Initiative to study the biological mechanisms contributing to coronavirus infections. EMBL group leaders Jan Korbel and Oliver Stegle, who is also affiliated with the DKFZ Heidelberg, will coordinate the set-up of IT infrastructures…

By Marius Bruer

Science

EMBL SPC facility supports COVID-19 projects

The Sample Preparation and Characterisation Facility (SPC) at EMBL Hamburg reopens to support scientists working on Covid-19 research. The SPC Facility is one of the best equipped facilities in Europe is therefore in high demand from external users. Re-opening the facility also allows experts at…

By Sara Verstraeten

Science

DNA damage and repair jointly leave mutational signatures in the genome.

DNA damage and faulty repair jointly cause mutations

DNA mutations are caused by a combination of DNA damage and repair, shows study by EMBL-EBI and collaborators.…

By Mehdi Khadraoui

Science

Liquid handling robot transfering protein crystalisation solutions

Responding to health threats posed by coronaviruses

By re-opening the High-Throughput Crystallisation (HTX) lab at EMBL Grenoble, EMBL is supporting structural biology projects to respond to the health threats posed by coronaviruses.…

By Sara Verstraeten

Science

Crystallization reagents being prepared by a pipetting robot at the HTX lab.

Remote access to EMBL structural biology pipelines to support research on SARS-CoV-2

The Marquez Team has restarted operations at the High-Throughput Crystallisation (HTX) lab at EMBL Grenoble. The team has developed a fully automated protein-to-structure pipeline, which can be operated remotely and provides virtual access to the facilities.…

By Sara Verstraeten

Science

Laboratory Officer Nicole Schieber working in EMBL's Electron Microscopy Core Facility. PHOTO: Viola Oorschot/EMBL

Taking a closer look at infected cells to better understand COVID-19

EMBL electron microscopy specialists collaborate with researchers from Heidelberg University Hospital to understand the changes occurring in cell structures upon SARS-CoV-2 infection.…

By Anne-Marie Alleaume

Science

The Influenza virus

Understanding the influenza virus

The infectious disease commonly known as flu is caused by the influenza virus. It spreads around the world in seasonal outbreaks, causing millions of infections and hundreds of thousands of deaths each year. Stephen Cusack, Head of EMBL Grenoble, has been studying different aspects of the influenza…

By Fabian Oswald

Science

Close-up view of the interior of a protein analytics system

Exploring synthetic antibodies to stop coronavirus

Scientists at EMBL Hamburg and Karolinska Institutet Stockholm aim to find synthetic antibodies – known as nanobodies – that bind a surface protein of the novel SARS-CoV-2 coronavirus. Nanobodies could prevent the virus from entering human cells and causing COVID-19.…

By Marius Bruer

Science

Artistic rendering of an RNA-binding protein interacting with an RNA molecule.

Helping researchers identify host proteins used by coronavirus

EMBL scientists working in the groups of Matthias Hentze and Wolfgang Huber have created RBPbase – a database of RNA-binding proteins – to assist the identification of proteins that interact with the SARS-CoV-2 RNA genome.…

By Marius Bruer

Science

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