Lab Matters, Science A new microscope built by EMBL researchers, based on Brillouin scattering principles, allows scientists to observe the dynamics of mechanical properties inside developing embryos in real time.
2023
lab-mattersscience
Science Using Oxford Nanopore long-read sequencing, EMBL scientists sequenced a primary childhood brain tumour known as a medulloblastoma, uncovering a novel complex mutation pattern.
2023
science
Research highlights, Science EMBL-EBI researchers use UK Biobank data to uncover new information about rare diseases of the eye.
2023
research-highlightsscience
Perspectives, Science As major biodiversity projects ramp up, EMBL-EBI enables genomic data sharing for all species.
2023
perspectivesscience
Perspectives, Science Why open data from model organisms is essential for rare disease research.
2023
perspectivesscience
Research highlights, Science Researchers create a network of interacting proteins – or interactome – to aid drug discovery.
2023
research-highlightsscience
Science In a first-of-its-kind study, EMBL researchers have shown how DNA methylation across the genome contributes to the precise regulation of gene expression.
2023
science
Perspectives, Science Open data played a pivotal role in the development of the AlphaFold AI. The same open principles now apply to AlphaFold predictions.
2023
perspectivesscience
Science EMBL researchers are stepping outside the lab and thinking outside the box to understand the basic principles that underlie the development and evolution of organismal characteristics.
2023
science
Science EMBL Grenoble scientists provide new insights into the function of an essential RNA editing enzyme.
2023
science
Announcements, Science Funding awarded for developing tools to harness marine microbiome data for biotechnological applications and ecosystem services.
2023
announcementsscience
Perspectives, Science Genomic sequencing and big data analysis are two novel technologies driving researchers’ understanding of the complexities of cancer.
2023
perspectivesscience
Science New artificial intelligence tool adds speed and detailed cellular information to analysis of cryo-electron tomography to aid researchers’ understanding of inner cell workings.
2023
science
Science, Technology and innovation Open Targets is using artificial intelligence and machine learning to identify and prioritise drug targets.
2023
sciencetechnology-and-innovation
Perspectives, Science We look back through some of the 2022 highlights from the Darwin Tree of Life project.
2023
perspectivesscience
Science EMBL Grenoble researchers have investigated the interaction between THC and some proteins it might bind to. In a recent study, they showed in vitro that THC inhibits an important human enzyme called autotaxin.
2023
science
Science EMBL Heidelberg researchers and their collaborators reveal how the nuclear pore complex, one of the biggest molecular machines in eukaryotic cells, is assembled one protein at a time.
2023
science
Research highlights, Science A new method developed by EMBL-EBI researchers helps to streamline nanopore sequencing in real-time.
2023
research-highlightsscience
Announcements, Science Open data resources that enable global research and development recognised by the Global Biodata Coalition.
2022
announcementsscience
Research highlights, Science Unveiling a useful tool for understanding human lung development.
2022
research-highlightsscience
Science Recent studies supported by EMBL Grenoble’s expertise in structural biology research and scientific services have identified Altiratinib as a potential drug to stop toxoplasmosis infection and opened up treatment options against malaria.
2022
science
Announcements, Science EMBL-EBI supports new European Commission project set to support the use of genomics in research and healthcare.
2022
announcementsscience
Announcements, Science Open Targets announces that Genentech will become the seventh partner in the drug discovery and validation consortium.
2022
announcementsscience
Perspectives, Science Our experts discuss the importance of open science for food security and preserving global biodiversity.
2022
perspectivesscience
Research highlights, Science Researchers have created a tool that maps in previously unseen detail how breast cancer develops and spreads.
2022
research-highlightsscience
Research highlights, Science Researchers use social media to share findings on how useful AlphaFold predictions are for different applications.
2022
research-highlightsscience
Announcements, Science Researchers across EMBL are helping to make artificial intelligence (AI) models for bioimaging analysis interoperable and openly available to the scientific community.
2022
announcementsscience
Science Plankton parasites provide a zombie story perfect for Halloween. While invading single-celled plankton, these parasites devour the cell’s nucleus and hijack metabolism while the organism remains alive.
2022
science
Announcements, Science NIH BRAIN Initiative to fund brain atlases, network coordination, and knowledge sharing to explore brain function research.
2022
announcementsscience
Science EMBL Barcelona researchers have developed a tool that can use light to control the shape of cells .
2022
science
Announcements, Science EMBL-EBI’s MGnify data resource helps researchers find enzymes for novel applications.
2022
announcementsscience
Science Researchers have combined advanced light microscopy with next-generation sequencing to create a method to study cells directly in the context of their native tissues
2022
science
Announcements, Science European experts gather to launch a project that aims to characterise and conserve life on Earth using DNA data.
2022
announcementsscience
Science New research by EMBL scientists shows at atomic detail how antibiotics affect the process of protein production inside bacteria.
2022
science
Science Researchers have come up with a way to test the efficacy of hundreds of anticancer drug combinations – simultaneously, rapidly, and accurately.
2022
science
Announcements, Science The Federated EGA is set to improve access to sensitive human data in a safe and secure way.
2022
announcementsscience
Science The latest research from EMBL’s Ikmi group employs interdisciplinary approaches to show how sea anemone ‘exercise’ changes their developing size and shape, uncovering an intimate relationship between behaviour and body development
2022
science
Science EMBL researchers used data from over 300 human faecal microbiota transplants to gain an ecological understanding of what happens when two gut microbiomes clash.
2022
science
Science EMBL researchers use a “fearless” computer reconstruction and a two-centuries-old mathematical approach to study limb bud growth.
2022
science
Perspectives, Science Ewan Birney, Deputy Director General of EMBL and Director of EMBL-EBI, reveals the key factors that enabled AlphaFold to change the world of biology.
2022
perspectivesscience
Research highlights, Science A new method for the robust analysis of copy number variation and used UK Biobank data to identify links between genome and disease.
2022
research-highlightsscience
Research highlights, Science International consortium analyses the genetic sequences and antibiotic susceptibility of 10,000 global Mycobacterium tuberculosis isolates.
2022
research-highlightsscience
Science How do gene expression patterns result in the generation of different cell types? Scientists at EMBL Heidelberg used the zebrafish notochord to find out.
2022
science
Science EMBL and UW researchers plus additional collaborators have constructed a complete map of fruit fly embryonic development using machine learning. This research is foundational to better understanding overall embryo development in other species, including humans.
2022
science
Research highlights, Science Machine learning has helped researchers uncover new insights into how bacteria infect host cells.
2022
research-highlightsscience
Science, Technology and innovation AlphaFold database offers a look at 3D protein universe.
2022
sciencetechnology-and-innovation
Science EMBL researchers now understand the function of an elusive small DNA in bacteria and have developed a tool that can be used to better understand what might ‘switch on’ bacterial immune defences.
2022
science
Science Microbial communities play essential roles in ocean ecology and planetary health. A recent publication highlights priorities for understanding and protecting ocean microbiomes.
2022
science
Research highlights, Science Scientists identify previously unexplored gene segments to be added to human genome databases.
2022
research-highlightsscience
Science EMBL research with Enolase 1 (ENO1) points to a possible new way to understand RNA’s leading role in how cells develop.
2022
science
Science Scientists have solved several mysteries around the structure and function of a true molecular giant: the human nuclear pore complex. They created the most complete model of the complex thanks to combining the program AlphaFold2 with cryo-electron tomography, integrative modelling, molecular…
2022
science
Science Researchers have discovered the mechanism by which a family of DNA motor proteins packages loosely arranged strands of DNA into compact individual chromosomes during cell division.
2022
science
Research highlights, Science Researchers discover how DNA mutations change blood cell production and how this relates to ageing and cancer development.
2022
research-highlightsscience
Science, Technology and innovation Researchers in the Ensembl team are making the most of machine learning methods to speed up genome annotation pipelines
2022
sciencetechnology-and-innovation
Science, Technology and innovation How text mining collaborations benefit our research, data resources, and the wider scientific community.
2022
sciencetechnology-and-innovation
Science Researchers at EMBL Heidelberg found that inversions in the human genome are more common than previously thought, which impacts our understanding of certain genetic diseases.
2022
science
Science EMBL researchers revise the old problem of sintering droplets to understand the mechanical properties of tissues.
2022
science
Perspectives, Science Virginie Uhlmann shares her tips for using deep learning for bioimage analysis in the life sciences.
2022
perspectivesscience
Science Scientists at EMBL Barcelona have created for the first time a 3D in vitro model that recapitulates the periodic formation of human somites – structures that give rise to the spinal column.
2022
science
Science Recent studies from the Hackett group at EMBL Rome have revealed new insights on the mechanism regulating transmission of non-genetic information during embryonic development, and inspired a scientific illustration
2022
science
Research highlights, Science Researchers from the MANE collaboration bring you the most comprehensive human genome annotation dataset to date.
2022
research-highlightsscience
Science Condensates are membraneless organelles that control specific functions within a cell. Scientists at EMBL Heidelberg have shown how the physical state of condensates can influence biological function.
2022
science
Perspectives, Science Zamin Iqbal and his team are working with researchers all over the globe to help put a stop to Tuberculosis
2022
perspectivesscience
Announcements, Science Our researchers highlight their contributions to the Darwin Tree of Life project and how new genome annotations helps to further biodiversity research
2022
announcementsscience
Perspectives, Science The African BioGenome Project aims to safeguard biodiversity and build bioinformatics capacity across Africa
2022
perspectivesscience
Science EMBL’s imaging technology helps researchers gain insights in the fungus’ journey from the lung to the brain.
2022
science
Science A molecular signature of 27 microorganisms in stool defines the high-risk population for the most common pancreatic cancer and could be used for early detection of the disease.
2022
science
Perspectives, Science Deep learning models can improve protein annotations and has helped expand the Pfam database.
2022
perspectivesscience
Science Genomes are made up of thousands of individual pieces – genes – which are expressed at different levels. Researchers at EMBL have shed light on how the placement of a gene affects its expression, as well as that of its neighbours.
2022
science
Science A recent study by EMBL researchers proposes a new method to grow early embryos in the laboratory. With a 3D culture set-up, scientists can closely monitor the changes embryos undergo around the time of implantation.
2022
science
Science Researchers from the Furlong group at EMBL have come up with a way to observe the development of fruit-fly embryos simultaneously at the genetic and cellular levels, generating a high-resolution and integrated view of how different cell lineages form.
2022
science
Announcements, Science Scientists urge the adoption of a sensible international policy for digital sequence information.
2022
announcementsscience
Announcements, Science Open Targets, a consortium focused on drug target identification, prioritisation, and validation, announced today that Pfizer has joined as a partner.
2022
announcementsscience
Science DeepMind visits EMBL Heidelberg to discuss current and future implications of Artificial Intelligence for life science research.
2022
science
Science EMBL Hamburg’s Grzegorz Chojnowski from the Wilmanns Group developed software called findMySequence, which identifies proteins’ amino-acid sequences based on electron cryo-microscopy and X-ray crystallography data. It’s useful for identifying unknown proteins in samples from natural sources.
2022
science
Perspectives, Science An exploration of where in the world genomics methods are applied and where the data are used.
2022
perspectivesscience
Science EMBL researchers, in collaboration with BD Biosciences, have demonstrated a new technology that allows rapid image-based sorting of cells. The new technology represents a major upgrade to flow cytometry and has applications in diverse life science fields.
2022
science
Announcements, Science On track to reach an ambitious goal of 3,000 genomes sequenced by the end of 2022, what’s next for the Earth Biogenome Project?
2022
announcementsscience
Science The Galej group at EMBL Grenoble has recently obtained high resolution snapshots of a crucial step in RNA splicing involving the U2 snRNP complex, a crucial component of the human spliceosome.
2022
science
Science Researchers have identified hundreds of new bacterial species and viruses in the human skin microbiome.
2022
science
Science EMBL Hamburg’s Kosinski Group, the Beck Laboratory at the Max Planck Institute of Biophysics, and colleagues at EMBL Heidelberg recorded the nuclear pore complex contracting in living cells. They visualised the movement with an unprecedented level of detail with help of new software called…
2021
science
Science Using cryo-EM and structural biology techniques, EMBL researchers have shown how two proteins of Legionella pneumophila interact. This finding sheds light on a mechanism critical to the infection process and could lead to the development of new drugs to treat pneumonia.
2021
science
Science A look back at some of the 2021 highlights from the Darwin Tree of Life partner institutes.
2021
science
Science The systematic application of AI in life sciences as in the AlphaFold algorithm for predicting protein structures has been named '2021 Breakthrough of the Year' by Science magazine.
2021
science
Science Bork Group at EMBL Heidelberg analysed a new global gene database to study how genes emerge and spread across various habitats on our planet. In the future, the group will expand the database and use it for studying microbial gene evolution and dispersal at a finer-grained scale.
2021
science
Science New structural biology research provides fundamental information critical to understanding enzyme mutations connected to rare diseases and cancers.
2021
science
Science Researchers studying a massive cohort of European patients have found that commonly prescribed drugs for cardiometabolic disorders can have long-term effects on the gut microbiome. Such effects can complicate the understanding of how disease affects the microbiome and must be taken into…
2021
science
Science RNA vaccines, such as the ones for COVID-19, represent a new approach in vaccine technology. Cy Jeffries, faculty staff scientist at EMBL Hamburg, explains the clever technology behind RNA vaccines, and how structural biology contributes to its development. EMBL Hamburg collaborated on several…
2021
science
Science EMBL structural biology is part of an international collaboration addressing zoonotic disease caused by Lassa virus.
2021
science
Science How genomics, open data, and multidisciplinary science can improve food security.
2021
science
Science The GA4GH Data Use Ontology (DUO) supports a data authorisation and access framework to streamline consent to use biomedical data
2021
science
Science A vast, curated collection of bacterial genomes is now organised, searchable and open to the community.
2021
science
Science What can sponges tell us about the evolution of the brain? Sponges have the genes involved in neuronal function in higher animals. But if sponges don’t have brains, what is the role of these? EMBL scientists imaged the sponge digestive chamber to find out.
2021
science
Science Scientists at EMBL Hamburg determined the molecular structure of Peptide Transporters 1 and 2. The findings will enable developing drugs that more efficiently pass from the gut to target tissues.
2021
science
Science The Darwin Tree of Life project is an unprecedented initiative sequencing 70,000 species
2021
science
Science International project uses biomolecular data to improve animal feed and make meat production more sustainable
2021
science
Science Using metagenomic data to find novel enzymes for plastic degradation and beyond
2021
science
Science EMBL Hamburg’s Sample Preparation and Characterisation (SPC) Facility has released eSPC, an online platform for analysing data from biophysical experiments. The platform enables the scientific community to analyse data from different experiments without the need to travel.
2021
science
Science The BY-COVID project aims to make infectious disease data, including COVID-19, openly available to everyone.
2021
science
Science Profiling M. tuberculosis strains from 27 countries to reveal causes of drug resistance.
2021
science
Science Researchers develop a new high-throughput approach to assess the functional significance of protein phosphosites.
2021
science
Science The Graham and Crump groups at the University of Cambridge and the Svergun Group at EMBL Hamburg have discovered a mechanism by which the herpes simplex virus takes control of the molecular machinery of human cells. Their work reveals how a dedicated viral protein hijacks key host proteins, forcing…
2021
science
Science Largest in-depth analysis of genomic data tracks the spread of SARS-CoV-2 lineages in England.
2021
science
Science Researchers from EMBL’s Typas group and collaborators have analysed the effects of 144 antibiotics on the wellbeing of gut microbes. The study improves our understanding of antibiotics’ side effects and suggests a new approach to mitigating the adverse effects of antibiotics therapy on gut…
2021
science
Science If researchers can identify specifically when good cells go bad, they can potentially understand disease better.
2021
science
Science Structural biology provides insights into the diverse functions of fibrous protein in humans, amphibians, and bacteria.
2021
science
Science EMBL scientists and colleagues have developed an interactive atlas of the entire marine worm Platynereis dumerilii in its larval stage. The PlatyBrowser resource combines high-resolution gene expression data with volume electron microscopy images.
2021
science
Science Scientists in EMBL’s Prevedel Group have developed a pioneering microscopy technique that allows researchers to observe cells hidden within opaque tissues, such as live neurons embedded deep in the brain.
2021
science
Science Some of the most amazing creatures live in the deep blue sea. The Mesoscopic Imaging Facility (MIF) at EMBL Barcelona was recently involved in studying one unique feature of the octopus: the ephemeral structures on the surface of their skin called Kölliker’s organs.
2021
science
Science MOrgAna is an open source, user-friendly, modular software that is able to analyse organoids with machine learning.
2021
science
Research highlights, Science EMBL scientists have found evidence of an unexpected role for retinal cells in pre-processing visual information; their results provide potential opportunity for future prosthetic visual aids.
2021
research-highlightsscience
Science 3D-Beacons Network acts as a one-stop shop for protein structures by combining and standardising data from several providers.
2021
science
Science A research collaboration used machine learning to map tumour molecular make-up, potentially paving way to more customised cancer treatment.
2021
science
Science Packaged for simple installation and free use, the novel method DECODE enables researchers to reduce imaging times and increase localisation density in single-molecule localisation microscopy (SMLM).
2021
science
Science A new collaborative study led by EMBL group leaders Kiran Patil, Nassos Typas, and Peer Bork has found that common medications accumulate in human gut bacteria. This process reduces drug effectiveness and affects the metabolism of common gut microbes, thereby altering the gut microbiome.
2021
science
Science In the Mesoscopic Imaging Facility (MIF) at EMBL Barcelona, researchers study the details of biological systems in the context of organs, body parts, or entire organisms. This image shows OPTiSPIM1, one of the custom light-sheet microscope setups available at the facility.
2021
science
Science Researchers have combined spatial gene expression information with single-cell genomics data to create a high-resolution atlas of mouse organogenesis.
2021
science
Science Analysis of more than 2 million images has boosted understanding of ocean microbes, shedding light on the distribution of nitrogen-fixers at a global level
2021
science
Science A collaboration led by EMBL Hamburg’s Svergun Group used small-angle X-ray scattering (SAXS) at the European XFEL to obtain data on samples containing coronavirus spike proteins and antibodies that bind them.
2021
science
Science Partners use AlphaFold, the AI system recognised last year as a solution to the protein structure prediction problem, to release more than 350,000 protein structure predictions including the entire human proteome to the scientific community.
2021
science
Science DeepMind and EMBL-EBI to make millions of protein structure predictions freely available to the scientific community.
2021
science
Science A discussion of the applications that AlphaFold DB may enable and the possible impact of the resource on science and society.
2021
science
Science Researchers establish a framework for identifying new drugs capable of exploiting a cell’s own machinery.
2021
science
Science EMBL scientists generate a high-resolution crystal structure of the Kinesin-1/aTm1 transport complex in the fruit fly.
2021
science
Science EMBL’s Melissa Graewert and colleagues are taking a structural biologist’s approach to better understanding nanoplastic particles.
2021
science
Science Research in the Typas group uncovers new details of the strategies Salmonella uses to survive in infected cells.
2021
science
Science EMBL Hamburg’s Wilmanns and Kosinski groups have determined the detailed structure of a bacterial protein complex critical for tuberculosis infection.
2021
science
Science After work in antimicrobial resistance, EMBL postdoc Laura Carroll is using machine learning for next-gen antibiotic development.
2021
science
Science Researchers investigate how external factors can influence the persistence of microbe species in the human gut
2021
science
Science New software enables scientists to visualise RNA secondary structures using the world’s largest RNA structure dataset.
2021
science
Science Under the innovative Planetary Biology research theme, EMBL scientists aim to understand life in the context of its environment.
2021
science
Science The largest in-depth analysis of genomic surveillance data mapping out the dynamics of 62 lineages of the SARS-CoV-2 virus.
2021
science
Science EMBL scientists support research on malaria by providing freely available data resources and using innovative experimental approaches. Our Course and Conference Office facilitates the exchange of knowledge in the field by hosting the annual BioMalPar conference.
2021
science
Science Researchers at EMBL Hamburg reveal how peg-like proteins clasp and reshape the cell membrane
2021
science
Science EMBL scientists have combined artificial intelligence (AI) algorithms with two cutting-edge microscopy techniques.
2021
science
Science EMBL Hamburg’s integrated structural biology facility has contributed to the success of a large-scale SARS-CoV-2 study
2021
science
Science Researchers reveal the best technology for assembling reference genomes.
2021
science
Science EMBL scientists, together with collaborators from Heidelberg University, have provided further evidence of the gut’s role in COVID-19.
2021
science
Science Researchers identify differences in immune response in asymptomatic COVID-19 cases compared to those with severe symptoms
2021
science
Science Researchers have used a metagenomics approach to piece together the genomes of yeasts found in wild lichens.
2021
science
Science Scientists from the CABANA project explore how open data is benefiting global research efforts.
2021
science
Science Researchers use large-scale human genetic studies to identify drug targets important for managing COVID-19 in its early stages
2021
science
Science Using EMBL Hamburg’s world-class structural biology infrastructure, researchers advance the folding of protein ‘origami’ designed in the lab.
2021
science
Science Researchers have used human medical and genetic data from UK Biobank to investigate the genetics of age-related diseases
2021
science
Science Scientists have determined the structure of Glycine Transporter 1. The finding could open new avenues for developing therapeutics for psychiatric disorders
2021
science
Science Scientists in the Stegle group and colleagues have studied induced pluripotent stem cells from around 1,000 donors to identify correlations between individual genetic variants and altered gene expression. They linked more than 4,000 of the genetic variants responsible for altered expression…
2021
science
Science Thousands of new protein structure models, prected using deep learning, now available to explore
2021
science
Science A new method has the potential to boost international research efforts to find drugs that eradicate cancer at its source.
2021
science
Science A collaboration including EMBL scientists has created the most diverse set of reference human genomes ever assembled.
2021
science
Science Scientists identify more than 140 000 virus species in the human gut; more than half have never been seen before
2021
science
Science Researchers from EMBL and Heidelberg University Hospital combine high-resolution imaging to observe the infection process in cell nuclei, opening the door for new therapeutics.
2021
science
Science A team of EMBL scientists and colleagues have analysed how the novel coronavirus affects proteins in human cells. They identified several human proteins as potential drug targets to prevent viral replication.
2021
science
Science Researchers at EMBL Heidelberg have identified sequences in human proteins that might be used by SARS-CoV-2 to infect cells. They have discovered that the virus might hijack certain cellular processes, and they discuss potentially relevant drugs for treating COVID-19.
2021
science
Science New EMBL research shows where & to what degree a component of cellular machinery known as RNA Pol III is mutated and becomes problematic.
2021
science
Science A new paper from the Galej group at EMBL Grenoble describes the structure of key parts of the Integrator complex, involved in gene expression.
2021
science
Science A new lineage of coronavirus was first identified in the UK, but why is it spreading much more rapidly within the population?
2021
science
Science A note on the coronavirus variant B.1.1.7, which has first been described in the U.K. and has spread to 57 countries. The note summarises epidemiological information about the spread of B.1.1.7 in the U.K. collated and in part conducted by researchers from EMBL-EBI.
2021
science
Science Freshwater sports can cause waterborne infections, but real-time DNA sequencing could help.
2021
science
Science Researchers at the Technion – Israel Institute of Technology and EMBL Hamburg, in collaboration with scientists in Israel and Spain, have discovered remarkable molecular properties of an antimicrobial peptide from the skin of the Australian toadlet. The discovery could inspire the development of…
2021
science
Science Understanding why disagreement is good for COVID science. EMBL Deputy Director General Ewan Birney offers tips for sorting through the discourse.
2021
science
Science Researchers discovered the dominant species of bacteria in kefir grains cannot endure without other species that help the 'team' survive.
2021
science
Science Despite restrictions, 2020 has been a busy year for the Darwin Tree of Life Project. We take a look at some of this year’s achievements and highlights.
2020
science
Science Gene activation requires the cooperative activity of multiple transcription factors. Until now, the mechanism used by these factors to coordinate their actions has been poorly understood. EMBL’s Krebs group presents a DNA footprinting method that makes it possible to determine whether…
2020
science
Science A new paper from EMBL’s Savitski team and Typas group describes their work on E. coli and how it brings a greater understanding of the way genes function and interact.
2020
science
Science While cryo-electron tomography (cryo-ET) was first envisioned in 1968, the advances the Mahamid group are bringing to this 3D method for studying molecules directly inside cells are new, and are likely to greatly expand its use.
2020
science
Science How artificial intelligence can help us solve the mysteries of the protein universe
2020
science
Science Scientists in the Diz-Muñoz group at EMBL Heidelberg are working to build understanding of the role that mechanical properties play in affecting cell behaviour – a young and rapidly developing field of study. They have developed and successfully used a highly specialised technique to manipulate…
2020
science
Science Members of the EMBL community are working to improve our understanding of the parasites that cause malaria and sleeping sickness
2020
science
Science Biotechnology company BioNTech and Johannes Gutenberg University Mainz conduct collaborative research with EMBL scientists at the beamline P12 in Hamburg
2020
science
Science Bioinformaticians at EMBL-EBI and beyond are adapting computational tools to investigate coronavirus genomes and proteins.
2020
science
Science Microbiomes, plastics, and connectivity – AtlantECO aims to understand the fabric of the Atlantic Ocean.
2020
science
Science Researchers have studied SARS-CoV-2 replication in cells and obtained detailed insights into the alterations induced in infected cells. This information is essential to guide the development of urgently needed therapeutic strategies for suppressing viral replication and induced pathology.
2020
science
Science By screening hundreds of sybodies (synthetic mini-antibodies), scientists have identified one that might stop SARS-CoV-2 from infecting human cells. This work, which holds promise for treating COVID-19, was conducted by EMBL Hamburg and collaborators from the Centre for Structural Systems Biology…
2020
science
Science Researchers in the Gross group at EMBL Rome have investigated the mechanism behind defensive behaviour in mice. They have identified a specific area of the brain that encodes both spatial and threat cues to drive location-specific defensive responses.
2020
science
Science Open access data benefits millions of scientists around the world and is essential for a rapid response to the COVID-19 pandemic.
2020
science
Science Scientists from the Beltrao Group at EMBL-EBI and collaborators identified drug targets common to SARS-CoV-2, SARS-CoV-1, and MERS-CoV, three pathogenic coronaviruses. They also found potential drugs that could be repurposed as COVID-19 treatments, and against emerging coronavirus strains in the…
2020
science
Science Researchers from EMBL Heidelberg have established an automated pipeline to create mutations in genomic enhancers, letting them watch evolution unfold before their eyes.
2020
science
Science A group of scientists led by EMBL Hamburg’s Christian Löw provide insights into the molecular structure of proteins involved in the gliding movements through which the parasites causing malaria and toxoplasmosis invade human cells.
2020
science
Science The genome editing tool CRISPR–Cas9 – which plays a critical role in EMBL’s research – was recognised by the Nobel Prize in Chemistry.
2020
science
Science Members of an EMBL-led research group with collaborators in Estonia and Russia have built and trained a deep learning model to better understand how cells grow and divide.
2020
science
Science The internal clock that governs the development of embryos ticks slower for humans than for mice. Differences in the speed of biochemical reactions underlie the differences between species in the tempo of development.
2020
science
Science Researchers have found the cause of dilated cardiomyopathy – a leading cause of heart failure – and identified a potential treatment for it: a drug already used to treat acne.
2020
science
Science The Gerstung Group at EMBL-EBI and collaborators have developed a statistical model that analyses genomic data to predict whether a patient has a high or low risk of developing oesophageal cancer.
2020
science
Science Scientists from the Beck group have studied the 3D structure of nuclear pores in budding yeast. They show how the architecture of the nuclear pore complex differs inside cells compared to its form observed in vitro studies.
2020
science
Science Researchers have uncovered how cells remove unwanted components from the nucleus following mitosis.
2020
science
Science An international group of researchers, led by scientists from EMBL Heidelberg, have discovered that the number of tentacle arms a sea anemone grows depends on the amount of food it eats.
2020
science
Science Starting with computer code and moving on to a more user-friendly graphical interface called PlantSeg, the Kreshuk Group at EMBL and collaborators built a simple open-access method to provide the most accurate and versatile analysis of plant tissue development to date.
2020
science
Science The beamlines run jointly by EMBL Grenoble and the ESRF reopen today, unveiling significant upgrades that exploit the brand new fourth generation ESRF synchrotron source.
2020
science
Science An international team of scientists involving Ewan Birney's group has investigated the function of a complex mesh of muscle fibres that line the inner surface of the heart.
2020
science
Science Discoveries at EMBL will help researchers to interpret one of the most common types of experiments in genomics and medical studies.
2020
science
Science Researchers studied the spike protein on the surface of the SARS-CoV-2 virus. With its spikes, the virus binds to human cells and infects them. The study gave surprising insights into the spike protein, including an unexpected freedom of movement and a protective coat to hide it from antibodies.
2020
science
Science A global team of researchers including the Flicek Team at EMBL-EBI has partnered up with the Māori tribe Ngātiwai to sequence the genome of the tuatara, a rare reptile endemic to New Zealand.
2020
science
Science The human genome harbours about 19 000 protein-coding genes, many of which still have no known function. As scientists unveil the secrets of our DNA, they come across novel genes that they need to refer to using a unique name. The Human Genome Organisation’s Gene Nomenclature Committee (HGNC) at…
2020
science
Science A new approach that allows researchers to see molecular machinery at work inside cells has offered a deeper understanding of how bacteria produce proteins and a unique glimpse into how they respond to antibiotics.
2020
science
Science Europe PMC has begun indexing full-text COVID-19 preprints along with the associated data. The project aims to accelerate research to fight the SARS-CoV-2 virus.
2020
science
Science EMBL scientists and collaborators help reveal the process by which enormous quantities of DNA are folded into cells.
2020
science
Science Researchers have developed an artificial intelligence algorithm that uses computer vision to analyse tissue samples from cancer patients. The algorithm can distinguish between healthy and cancerous tissues, and can also identify patterns DNA and RNA changes in tumours.
2020
science
Science EMBL scientists have created a new, realistic 3D testbed that could help achieve the goal of stopping cancers before they start by studying cancer cells as they first form.
2020
science
Science An international team of scientists has collated all known bacterial genomes from the human gut microbiome into a single large database. Their work will allow researchers to explore the links between bacterial genes and proteins, and their effects on human health.
2020
science
Science Scientists at EMBL Heidelberg have investigated stem cells and how they differentiate to become neurons. Their approach included an assessment of the complex interplay of molecules during the differentiation process and generated fundamental new insights into the role of a protein called Sox2 in…
2020
science
Science A study conducted by the Hackett group at EMBL Rome has identified key factors controlling the complex system of gene regulation during early embryo development, shedding new light on the mechanisms behind these events and on their evolutionary implications. Their findings are published in Nature…
2020
science
Science To study how SARS-CoV-2 infects cells, the Gene Editing and Embryology Facility (GEEF) at EMBL Rome will generate mice that express a human version of a protein called ACE2. The mouse line will be shared with preclinical research collaborators carrying out vaccine and antibody trials, and with the…
2020
science
Science Researchers evaluate how the new coronavirus rewires human proteins for its own replication, and identify several antiviral drugs ready for clinical trials
2020
science
Science Today we celebrate the 20th anniversary of the first draft of the entire human genome.
2020
science
Science EMBL scientists develop a new molecular tool to prevent SARS-CoV-2 infection in mice. This tool is able to cause targeted epigenetic modifications of specific genes in specific cell populations. They will use it in mice to target airway cells that express the ACE2 protein – the receptor that…
2020
science
Science DNA damage caused by chemical mutagens is not repaired immediately and can create more genetic diversity in tumours.
2020
science
Science While global research on coronaviruses has shed light on the function of many SARS-CoV-2 proteins, the role of some crucial components remains unknown. Researchers at EMBL Grenoble will use a range of structural biology methods to try to solve some of the puzzles of the molecular mechanics of…
2020
science
Science Scientists at EMBL and Heidelberg University Hospital are studying how the novel coronavirus behaves in the gut to try to better understand its epidemiology and prevent its spread. To do this, they are combining advanced imaging and sequencing technologies to study coronavirus in human intestinal…
2020
science
Science Scientists discovered that antihypertensive agent alters the tissue characteristics of colon cancer metastases. This "stiffness" of metastases has an effect on the therapeutic success.
2020
science
Science Scientists at EMBL Rome unveil the mechanism behind the most studied epigenetic modification.
2020
science
Science Researchers in the Marcia group at EMBL Grenoble and the De Vivo lab at the Italian Institute of Technology in Genoa have obtained some of the most detailed ever snapshots of the splicing process in systems known as group II self-splicing introns. The new insights will help scientists to develop…
2020
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Science EMBL researchers are studying COVID-19-related molecules by exposing them to high-brilliance X-ray beams. The Svergun group at EMBL Hamburg is using biological small-angle X-ray scattering (SAXS) as part of a global effort by scientists to elucidate the structural organisation of SARS-CoV-2…
2020
science
Science Scientists including members of EMBL’s Typas group have investigated how immune cells called macrophages respond to infection by the intracellular pathogen Salmonella enterica. They discovered that Salmonella causes newly produced cathepsins to accumulate in the nuclei of infected cells to…
2020
science
Science Scientists at EMBL Heidelberg have developed a new method, called Targeted Perturb-seq (TAP-seq), which increases the scale and precision of functional genomics CRISPR–Cas9 screens by orders of magnitude. Their method overcomes limitations in previous applications of single-cell RNA sequencing,…
2020
science
Science Researchers from EMBL Grenoble have developed a way to visualise large RNAs in 3D using biochemical and structural biology techniques.
2020
science
Science EMBL and the European Synchrotron Radiation Facility (ESRF) restart the activities of the Joint Structural Biology Group in Grenoble to support coronavirus-related projects. A new initiative will allow users to be granted access to the High-Throughput Crystallisation (HTX) lab at EMBL and to a…
2020
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Science EMBL scientists have performed a large-scale analysis of over 4700 SARS-CoV-2 genome sequences. They found that many of the most interesting changes in the SARS-CoV-2 genome that have been reported so far are likely to be technical artefacts, rather than biological mutations.
2020
science
Science Scientists hope that a legacy of the novel coronavirus in recovered COVID-19 patients – antibodies in their blood – could lead to drugs to treat others. The Merten group at EMBL Heidelberg has pivoted its microfluidics platform to support the search for neutralising antibodies that could…
2020
science
Science Researchers in EMBL’s Zaugg group have studied the causes of pulmonary arterial hypertension (PAH), a rare disease that causes high blood pressure in the arteries of the lungs. The study, carried out in collaboration with Stanford University School of Medicine, compared lung cells of patients…
2020
science
Science Researchers from the Sharpe group at EMBL Barcelona have published a method to track the developmental history of a cell using the gene editing tool CRISPR–Cas9, but without the need to create transgenic organisms.
2020
science
Science EMBL scientists will contribute to the new German COVID-19 OMICS Initiative to study the biological mechanisms contributing to coronavirus infections. EMBL group leaders Jan Korbel and Oliver Stegle, who is also affiliated with the DKFZ Heidelberg, will coordinate the set-up of IT infrastructures…
2020
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Science The Sample Preparation and Characterisation Facility (SPC) at EMBL Hamburg reopens to support scientists working on Covid-19 research. The SPC Facility is one of the best equipped facilities in Europe is therefore in high demand from external users. Re-opening the facility also allows experts at…
2020
science
Science DNA mutations are caused by a combination of DNA damage and repair, shows study by EMBL-EBI and collaborators.
2020
science
Science By re-opening the High-Throughput Crystallisation (HTX) lab at EMBL Grenoble, EMBL is supporting structural biology projects to respond to the health threats posed by coronaviruses.
2020
science
Science The Marquez Team has restarted operations at the High-Throughput Crystallisation (HTX) lab at EMBL Grenoble. The team has developed a fully automated protein-to-structure pipeline, which can be operated remotely and provides virtual access to the facilities.
2020
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Science EMBL electron microscopy specialists collaborate with researchers from Heidelberg University Hospital to understand the changes occurring in cell structures upon SARS-CoV-2 infection.
2020
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Science The infectious disease commonly known as flu is caused by the influenza virus. It spreads around the world in seasonal outbreaks, causing millions of infections and hundreds of thousands of deaths each year. Stephen Cusack, Head of EMBL Grenoble, has been studying different aspects of the influenza…
2020
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Science Scientists at EMBL Hamburg and Karolinska Institutet Stockholm aim to find synthetic antibodies – known as nanobodies – that bind a surface protein of the novel SARS-CoV-2 coronavirus. Nanobodies could prevent the virus from entering human cells and causing COVID-19.
2020
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Science EMBL scientists working in the groups of Matthias Hentze and Wolfgang Huber have created RBPbase – a database of RNA-binding proteins – to assist the identification of proteins that interact with the SARS-CoV-2 RNA genome.
2020
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Science In March 2020, planes were grounded, streets went quiet, and our lives changed forever. But while the world came to a halt, many scientists were ramping up their efforts to understand the new virus.
2020
science
Science Researchers from EMBL Heidelberg have created a complete description of early embryo development, accounting for every single cell in the embryo.
2020
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Science The new collaborative space will help scientists, public health and healthcare professionals around the world to fight the coronavirus pandemic.
2020
science
Science EMBL Heidelberg reopens the Cryo-Electron Microscopy Service Platform to support coronavirus structural biology research.
2020
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Science Scientists at EMBL Heidelberg are contributing their expertise in a community effort to develop large-scale testing methods for coronavirus. Their goal is to increase the capacity and speed of testing, which is crucial for containing the pandemic.
2020
science
Science EMBL researchers are studying how drugs that have shown good results against COVID-19 work in living cells
2020
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Science The Protein Expression and Purification Core Facility at EMBL Heidelberg will produce proteins for several coronavirus-related research projects, to assist the development of new strategies to fight the virus.
2020
science
Science EMBL researchers in the Heard group at EMBL Heidelberg explore the interaction between DNA organisation and gene expression in the early embryo
2020
science
Science EMBL scientists examine the molecular causes of a rare hereditary disease of the spine and ribs
2020
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Science The causes of 40 percent of all cases of certain medulloblastoma – dangerous brain tumours affecting children – are hereditary. These are the findings of a recent genetic analysis carried out by scientists from EMBL and numerous colleagues around the world.
2020
science
Science EMBL-EBI set to launch European COVID-19 Data Platform to help store, share, and analyse research data linked to the COVID-19 pandemic.
2020
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Science The Heidelberg-based LeukoSyStem consortium investigates leukaemia stem cells in acute myeloid leukaemia. The German Federal Ministry of Education and Research financially supports this collaboration between Heidelberg University Hospital, HI-STEM gGmbH, the German Cancer Research Center and EMBL.
2020
science
Science EMBL researchers investigate the role of a histone protein in regulating gene expression
2020
science
Science EMBL researchers combine multiple datasets to develop expandable atlas of an entire animal
2020
science
Science New group leader at EMBL Heidelberg employs synthetic chemistry to develop novel tools for biology
2020
science
Science This technique provides a simple but effective way to study the functions of organs in living animals
2020
science
Science Scientists provide important new insights into the molecular basis of X-inactivation
2020
science
Science EMBL co-leads most comprehensive study of genetic causes of cancer
2020
science
Science Cloud computing offers unprecedented opportunities for global-scale research collaborations. It also presents a unique set of challenges in terms of data protection and the ethics of data sharing.
2020
science
Science The largest and most comprehensive catalogue of cancer-specific RNA alterations reveals new insights into the cancer genome.
2020
science
Science Researchers at EMBL’s European Bioinformatics Institute (EMBL-EBI) and the Francis Crick Institute have analysed the whole genomes of over 2600 tumours from 38 different cancer types to determine the chronology of genomic changes during cancer development.
2020
science
Science Scientists from EMBL present a tool for large-scale analysis of genomic data with cloud computing. Main advantages of the new tool, called Butler, are continuous system monitoring and its ability to self-heal in case of failure, allowing for 43% more efficient data processing than previous…
2020
science
Science Using the dataset from the Pan-Cancer project, scientists has developed methods to group, classify, and describe large rearrangements of the genome that are a key driver of cancer.
2020
science
Science Analysis of whole cancer genomes gives key insights into the role of the non-coding genome in cancer
2020
science
Science Researchers at Harvard Medical School and EMBL-EBI have carried out the largest analysis across cancer types of the newly discovered mutational phenomenon chromothripsis.
2020
science
Science Using the data from the Pan-Cancer project EMBL scientists describe how our genetic background influences cancer development.
2020
science
Science New resource that categorises genes essential for supporting life could be used to identify rare disease mutations
2020
science
Science Strengthening ties between EMBL and Israel through the Scientific Visitor Programme
2020
science
Science New group leader at EMBL Barcelona is investigating how malaria affects the human circulatory system
2020
science
Science EMBL researchers have developed a method to observe interactions between transcription factors
2020
science
Science Kristina Haase brings an engineer’s perspective to vascular disease and regenerative medicine
2020
science
Science EMBL scientists identify drug targets in blood and organs
2020
science
Science Researchers have developed a cheaper and faster method to check for genetic differences in individual cells
2019
science
Science Researchers have developed new methods to reveal the 3D-organisation of bone marrow at a single cell level
2019
science
Science The software diffTF quantifies activity of transcription factors and predicts their mode of action
2019
science
Science Resource has implications for disease research
2019
science
Science A new paper describes a unique mechanism of partner selectivity in transcription factors.
2019
science
Science Exploring the diverse routes by which EMBL scientists are driving forward neurobiology
2019
science
Science Crick and EMBL PhDs talk science over coffee
2019
science
Science Shedding light on the mechanisms that control the fate of embryonic cells
2019
science
Science A new technique in cryo-EM
2019
science
Science EMBL researchers have published two new studies involving the nuclear pore complex
2019
science
Science Children's rights stored in synthetic DNA
2019
science
Science New possibilities for gene therapies
2019
science
Science EMBL’s Genomics Core Facility supports students participating in the annual iGEM competition.
2019
science
Science Funding awarded to EMBL-EBI for tuberculosis monitoring tool
2019
science
Science Researchers from Hamburg simplify time-resolved X-ray crystallography
2019
science
Science Immunotherapy: the role of B cells
2019
science
Science Exploring the cancer genomics labyrinth
2019
science
Science MEG3 adopts a complex three-dimensional structure to fulfil its tumour suppressor function.
2019
science
Science Understanding how ageing works at a molecular level
2019
science
Science Schoolchildren get creative with 3D protein structures
2019
science
Science Eric Karsenti's combined loves of biology and sailing set in motion the Tara Oceans expedition
2019
science
Science Enhancers in Drosophila embryos gather together to preserve phenotypes under stressful conditions
2019
science
Science SidJ enforces a unique modification on human proteins and helps legionella grow.
2019
science
Science Michael Zimmermann's group will investigate how gut microbes affect the body’s response to drugs.
2019
science
Science EMBL scientists collaborate to develop new protocol for screening membrane protein stability
2019
science
Science Does rearranging chromosomes affect their function? EMBL scientists reveal uncoupling of 3D chromatin organisation and gene expression.
2019
science
Science Using cryo-EM, scientists have determined the structure of a large protein complex called Elongator.
2019
science
Science How computer processing of human language is harnessed by EMBL scientists
2019
science
Science What CRISPR may bring for the future of biology, and how it is used at EMBL
2019
science
Science New insights into mechanisms behind embryonic development
2019
science
Science The BioImage Archive - EMBL-EBI's first dedicated imaging data resource
2019
science
Science A conversation about art-science collaborations and the importance of drawing in biology.
2019
science
Science The increasing importance of code in the biological sciences
2019
science
Science Using genomics to help endangered species
2019
science
Science The mystery of how condensin maintains the integrity of the genome during cell division.
2019
science
Science Uncovering new role of fluid pressure in controlling embryo size and cell fate
2019
science
Science Snapshots of the flu virus replication machine in action
2019
science
Science Tara Ocean Foundation launches the exploration of 10 European rivers
2019
science
Science Scientists develop software tools for automated acquisition of electron microscopy data
2019
science
Science A newly developed 3D microscope visualises fast biological processes better than ever.
2019
science
Science Results from the Tara Oceans expedition reveal the Arctic Ocean as a cradle of viral biodiversity
2019
science
Science EMBL scientists have discovered that the proteome is substantially affected by both sex and diet
2019
science
Science Thorough characterisation of structural variants in human genomes
2019
science
Science Large CRISPR screen prioritises hundreds of promising genes for personalised cancer treatment
2019
science
Science Colorectal cancer characterised by consistent changes in gut bacteria across continents, cultures and diets
2019
science
Science EMBL scientists create membraneless organelle to build proteins in living cell
2019
science
Science New EMBL group leader explores what neurobiology can teach us about what it means to be human
2019
science
Science Scientists develop technology to measure how ATP concentration affects protein solubility in cells
2019
science
Science New group leader at EMBL Grenoble is investigating the cellular role of melanoma antigens
2019
science
Science Many microbes traverse the oral-gut barrier
2019
science
Science How organs form in a mouse embryo
2019
science
Science Suicide system in tuberculosis bacteria might hold key to treatment
2019
science
Science EMBL scientists identify RNA regulating protein behaviour in switch of normal roles
2019
science
Science Researchers identify novel gut bacteria species and call for more data from beyond Europe and North America
2019
science
Science A new database of bacteria in the human microbiome is the most comprehensive to date.
2019
science
Science New search engine allows researchers to identify antibiotic resistance genes or mutations in real time
2019
science
Science Scientists develop high-throughput yeast single-cell RNA sequencing method
2019
science
Science Scientists develop structural model that could help in the development of drugs with increased absorption rates
2019
science
Science Federated data sharing will now be possible on an unprecedented scale
2019
science
Science Scientists build self-organising features into robot swarms to study shape formation
2018
science
Science EMBL researchers have found a way to stop itch with light in mice
2018
science
Science Cancer researchers have developed a computer model to predict the course of disease for prostate cancer
2018
science
Science Researchers develop new method to analyse the entire protein-RNA network of the cell
2018
science
Science EMBL-EBI industry case study: Biocatalysts
2018
science
Science New algorithm will enhance understanding of relationship between genotype and environmental factors
2018
science
Science Scientists uncover effects of mutation that can cause autism and intellectual disability
2018
science
Science The De Renzis group investigated invagination, the first step of organ development in embryos.
2018
science
Science Genomes of 66,000 UK species to be sequenced in global effort to sequence all known eukaryotic species
2018
science
Science EMBL scientists investigate the structure of a key protein involved in blood clotting
2018
science
Science The Hentze Lab enhanced a RNA-interactome capture technique to pave the way towards medical progress
2018
science
Science Speeding up time-resolved X-ray crystallography with EMBL beamline P14
2018
science
Science EMBL researchers discover that four organs in a marine worm’s head can sense different chemicals
2018
science
Science New study reveals how to make therapeutic insulins more effective than they currently are
2018
science
Science ERC grantees Wolfgang Huber and Oliver Stegle share their vision for the next 10 years
2018
science
Science How embryonic stem cells develop into the germ line
2018
science
Science EMBL scientists gain mechanistic insights into how cellular signalling controls gene regulation
2018
science
Science Researchers from EMBL and Heidelberg University unveil the molecular mechanisms of ageing
2018
science
Science Retromer’s 3D structure improves understanding of cellular sorting and packaging
2018
science
Science X-ray experiments show that scaffolding protein PDZK1 has a L-shaped conformation
2018
science
Science Real-time tracking of proteins during mitosis is now possible using a 4D computer model
2018
science
Science Complex metabolomics analyses in the cloud
2018
science
Science EMBL scientists discover how a component of the cohesin ring binds DNA
2018
science
Science Large-scale systematic analysis explores how inherited genome affects drug response of cancer cells
2018
science
Science New head of the Mesoscopic Imaging Facility at EMBL Barcelona will help scientists visualise nature
2018
science
Science An engineer’s approach to understanding morphogenesis
2018
science
Science First global survey of soil genomics reveals a war between fungi and bacteria
2018
science
Science EMBL researchers visualise the proteins needed to capture molecules and bring them into a cell
2018
science
Science The Protein Data Bank in Europe celebrates its schools art project with its largest exhibition yet
2018
science
Science Europe PMC adds preprints to its search
2018
science
Science Mammalian life begins differently than we thought
2018
science
Science Scientists show how bacteria and other microorganisms are passed on from mother to child
2018
science
Science Acute myloid leukaemia risk could be detected years before diagnosis
2018
science
Science New group leader at EMBL Barcelona creates artificial biological systems to study animal development
2018
science
Science EMBL scientists investigate how bacteria melt to study their reaction to drugs
2018
science
Science Combining antibiotics with each other, non-antibiotic drugs or food additives can alter their effectiveness
2018
science
Science EMBL scientists reveal NPC architecture of algae
2018
science
Science EMBL scientists investigate how influenza virus responds to new drug treatment
2018
science
Science EMBL researchers develop method that simplifies the isolation of DNA- and RNA- protein complexes
2018
science
Science Combinations of cancer drugs can be quickly and cheaply tested using a novel microfluidic device
2018
science
Science EMBL scientists extend Turing’s theory to help understand how biological patterns are created
2018
science
Science New computational method uses multi-omics analysis for personalised medicine
2018
science
Science EMBL researchers guide the shape of cells and tissues with optogenetics
2018
science
Science Which of our genes will be passed on to our children? Simone Köhler wants to find out
2018
science
Science Of mice and gorillas: using mouse data for conservation
2018
science
Science Scientists at EMBL Hamburg determine shapes of intermediate states in dynamic biological systems
2018
science
Science EMBL’s next Director General reflects on the questions that drive her research
2018
science
Science EMBL group leader Jan Korbel reflects on his scientific origins and current research
2018
science
Science Researchers identify genes that can cause brain tumours in children and other cancers later in life
2018
science
Science New platform transforms CRISPR gene editor into precision tool
2018
science
Science What worms can tell us about cancer
2018
science
Science EMBL scientists uncover large solubility and thermal stability changes of proteins during the cell cycle
2018
science
Science Discover how EMBL scientists are using GPU computing to push biology forward
2018
science
Science Scientists at EMBL Rome develop new method that uses light to manage neuropathic pain in mice
2018
science
Science New Heidelberg group leader creates tools to help biologists work faster and better
2018
science
Science Dog and human gut microbiomes have more similar genes and responses to diet than previously thought
2018
science
Science Open-source software allows standard microscopes to accurately image 3D structures
2018
science
Science EMBL scientists count and locate chromosomal proteins during cell duplication
2018
science
Science Launch of the first free global online catalogue of PDX models
2018
science
Science New EMBL-EBI Group Leader will make sense of bioimaging data
2018
science
Science For the first time, EMBL Rome researchers have captured microglia nibbling on brain synapses on film.
2018
science
Science What does a cell's location tell us?
2018
science
Science The new head of facility at EMBL Hamburg will help users solve protein puzzles
2018
science
Science EMBL scientists discover how blood vessel cells become blood stem cells during embryonic development
2018
science
Science One in four drugs with human targets inhibit the growth of bacteria in the human gut, and may promote antibiotic resistance, EMBL researchers report in Nature
2018
science
Science EMBL scientists show how to grow a wide range of gut bacteria in the lab
2018
science
Science EMBL scientists unravel the molecular basis of a major antibiotic resistance transfer mechanism
2018
science
Science Scientists at EMBL and Cellzome develop technology to monitor the effects of drug treatments on protein degradation and synthesis
2018
science
Science EMBL scientists show how chromatin usage in individual cells reveals developmental trajectories
2018
science
Science EMBL scientists discover how two guidance cues work together when neurons project axons across the midline
2018
science
Science Is depression in your genes?
2018
science
Science Join us in our new editorial theme as we ask how everything began
2018
science
Science New technique offers insight into early cell life
2018
science
Science Access to state-of-the-art microscopes and outstanding expertise
2018
science
Science Researchers from Delft University and EMBL crack the mystery of condensin’s neat DNA loop extrusion
2018
science
Science EMBL scientists show that the rhythm between Wnt and Notch waves enables patterning in embryos.
2018
science
Science EMBL scientists discover how a molecule’s role changes from simple metabolite to instructive signal
2018
science
Science New EMBL group leader explores biophysical properties of chromosomes and other cellular assemblies
2018
science
Science EMBL scientists create a turnover catalogue of almost 10.000 proteins from primary cells
2018
science
Science Network of genes linked to development of diabetes
2018
science
Science How Darwin’s work revealed the intimate relationship between orchids and insects
2018
science
Science EMBL’s new group leader studies how gene expression is controlled
2018
science
Science EMBL scientists show that some promoters can act as enhancers and vice versa
2018
science
Science Nick Goldman of EMBL-EBI issued a challenge in 2015. In 2018, a winner emerged just in time.
2018
science
Science EMBL researchers uncover how a key enzyme that helps cells make new proteins starts its work
2018
science
Science New EMBL group leader investigates the mystery of heritable gene silencing
2018
science
Science New group leader studies sea anemones to investigate why some animals regenerate better than others
2018
science
Science EMBL researchers solve a decades-long debate on a key process for brain and embryo-development
2018
science
Science EMBL scientists unveil how 3D chromatin structure affects RNA splicing
2017
science
Science Molecule mapping method raises interest in forensics, agriculture and microbiome studies
2017
science
Science What are the strangest genomes in EMBL-EBI's Ensembl?
2017
science
Science ERC grantee Stephen Cusack shares his vision for the next ten years
2017
science
Science New research reveals that two different mechanisms are responsible for chromosome folding
2017
science
Science EMBL scientists superimpose structures of two-metal-ion enzymes and reveal new potential drug targets
2017
science
Science New research shows how pores form in the membrane that surrounds a cell’s nucleus
2017
science
Science High resolution 3D protein structures in a giffy with PDBe
2017
science
Science New group leader based in Grenoble aims to unveil the mechanisms of RNA editing
2017
science
Science New BioModels infrastructure supports significantly more model formats and offers improved search
2017
science
Science New method for 3D imaging microorganisms lends insight into the creatures that inhabit our oceans
2017
science
Science The Mahamid group studies meso-scale molecular assemblies in intact cells and model organisms at molecular resolution
2017
science
Science Insights into the reproduction of Plasmodium parasites in mosquitoes reveal rapid and broad activity
2017
science
Science EMBL researchers create highest resolution 3D model of important structure within Ebola virus
2017
science
Science Inside the Centre for Structural Systems Biology
2017
science
Science A summary of recent research highlights from EMBL
2017
science
Science As a new cryo-EM facility is inaugurated, EMBL’s Michael Hons describes his role in the project
2017
science
Science How open data is changing our pursuit of discovery
2017
science
Science A talent for organisation has taken EMBL’s Steffi Kandels-Lewis across the globe
2017
science
Science Five things researchers have learned from bizarre fruit flies
2017
science
Science Find out how curiosity is driving some of the work we do here at EMBL
2017
science
Science EMBL researchers and collaborators unravel how chromosomes form
2017
science
Science EMBL alumnus recognised for cryo-electron microscopy work
2017
science
Science EMBL’s new group leader based in Hamburg aims to create models of infection cycles
2017
science
Science Q&A with EMBL-EBI's Head of Chemical Biology data services
2017
science
Science How microbes can create niches for each other
2017
science
Science New study by Paola Kuri and Maria Leptin shows how inflammation happens in zebrafish in real time
2017
science
Science Newly opened European X-Ray Free-Electron Laser celebrates start of user operations
2017
science
Science How patient-derived computational models can help researchers understand cancer
2017
science
Science Meet Justin Crocker, EMBL’s new group leader in gene regulation during evolution and development
2017
science
Science A new group at EMBL-EBI aims to decipher cell signalling networks
2017
science
Science The Iqbal research group hopes to build a 'Google of bacteria' to help better interpret the genome
2017
science
Science Genetic data from a major cohort now distributed via EMBL-EBI
2017
science
Science EMBL’s Iain Mattaj, the new Chair of EIROforum, on EIROforum’s role
2017
science
Science IMPC explains how much the sex of animals is misdirecting research results
2017
science
Science EMBL-EBI and IMPC characterised over 3000 mouse genes, revealing new gene associations with disease
2017
science
Science The Image Data Resource - prototype of the first open repository linking imaging and molecular data
2017
science
Science EMBL’s Cornelius Gross wants to understand fear responses and the brain circuitry that governs them
2017
science
Science EMBL researchers complete a molecular atlas showing gene expression in all cells in an entire animal
2017
science
Science Two EMBL researchers are exploring new ways to filter out noise and get to the data they need
2017
science
Science EMBL’s Hiroki Asari investigates how our internal state can change the way our eyes work
2017
science
Science Meet the head of EMBL's new Barcelona site, James Sharpe
2017
science
Science An EMBL collaboration devises a new method that could speed up vaccine development for HIV
2017
science
Science Hallmarks of residual breat cancer cells suggest new approaches for preventing relapse
2017
science
Science Introducing one of the largest collections of high-quality human induced pluripotent stem cells
2017
science
Science Meet Monterotondo’s new group leader for epigenetic reprogramming and inheritance, Jamie Hackett
2017
science
Science ERC grantee Maja Köhn shares her vision for the next ten years
2017
science
Science EMBL researchers develop an optical method for measuring the release of insulin from single cells
2017
science
Science EMBL scientists detect important function of genetic sequence our ancestors assimilated from a virus
2017
science
Science EMBL-EBI researchers identify mouse epigenetic clock that could help scientists understand ageing
2017
science
Science EMBL scientists add crucial knowledge to understanding of the bacterium that causes tuberculosis
2017
science
Science Study by EMBL and DKFZ researchers means origins of myeloid leukaemias may need rethinking
2017
science
Science Researchers use single-cell sequencing to understand how cells age
2017
science
Science ERC grantee Edward Lemke shares his vision for the next ten years
2017
science
Science ERC grantee Detlev Arendt shares his vision for the next ten years
2017
science
Science ERC grantee Eileen Furlong shares her vision for the next ten years
2017
science
Science Keeping bacterial chromosomes tangled could lead to new approaches to treatment
2017
science
Science Reconstructing T-cell development in high resolution
2017
science
Science EMBL researchers develop a computer model to explore the movement of nuclei in a multinuclear cell
2017
science
Science Differentiated and undifferentiated cells get energy in different ways, sensor made at EMBL shows
2017
science
Science A new technique developed at EMBL reveals the way fats interact with other molecules in cells
2017
science
Science EMBL scientists discovered that common mutations can change the shape of gene promoters
2017
science
Science Healing and anxiety are influenced by the genetics of one’s social partners
2017
science
Science New group leader Wojciech Galej investigates RNA-protein complexes involved in gene expression
2017
science
Science New mechanism revealed
2017
science
Science EMBL scientists find out how the prefrontal cortex puts a break on instinctive behaviours
2017
science
Science Understanding how the flu virus steals host RNA offers hope of new drugs
2016
science
Science Inducible mechanism found by EMBL scientists links receptor degradation and replenishment
2016
science
Science EMBL scientists use new techniques to describe the architecture of conical HIV capsids
2016
science
Science Research on the effect of nerve cell stiffness on sensitivity to touch could lead to new painkillers
2016
science
Science Paul Nurse’s failed experiment inspired a career that would uncover key mechanisms of cell division
2016
science
Science New method combines signalling pathway data resources to improve systems biology research
2016
science
Science How Christian Löw’s failed experiment led to an unexpected scientific journey
2016
science
Science Exploring what it would take to regrow a lost limb, and what we might learn along the way
2016
science
Science Parasite’s method of rewiring our immune response leads to novel tool for drug tests
2016
science
Science BLUEPRINT: EMBL-EBI and the push to decipher the blood epigenome
2016
science
Science Cryo EM reconstruction of RNA Polymerase I reveals details of how molecule binds and transcribes DNA
2016
science
Science Open source bioinformatics method for finding metabolites makes experiments comparable across labs
2016
science
Science Where design meets bioinformatics, new scientific perspectives abound.
2016
science
Science What happens when plant's leaf-placing feedback loop isn't quite right
2016
science
Science Robert Prevedel develops deep-tissue microscopy for scientists to peer deep inside living organisms
2016
science
Science New platform useful for studies of protein binding, human tissue and more
2016
science
Science A rapid, versatile mechanism that modifies proteins is revealed to be crucial for the evolutionary process
2016
science
Science EMBL scientists investigate how leaves grow flat to efficiently capture sunlight
2016
science
Science IMPC study identifies 410 genes essential to life in the mouse, providing a window on human disease
2016
science
Science Side-effects of leukaemia drug explained, reveal possibility of repurposing to treat other diseases
2016
science
Science New head of Proteomics Core Facility also runs stability proteomics lab
2016
science
Science Puzzle of nuclear pore formation in growing nuclei solved
2016
science
Science EMBL researchers help to design a lead compound active against four different pathogens
2016
science
Science Collaborating to take crystallography into a new time dimension
2016
science
Science 3D printing, gaming, virtual reality and lenticular posters bring new perspectives to research
2016
science
Science Emmanuelle Charpentier sheds light on how CRISPR–Cas9 went from side project to global revolution
2016
science
Science EMBL and ESRF scientists and mechanics work together on upgrade for one of Europe’s big X-ray sources
2016
science
Science 'The PDB plays a crucial role in structural biology research and development'
2016
science
Science Team leader investigates how the gut microbiome could relate to human diseases
2016
science
Science Storage of pre-made nuclear pores allows for rapid cell division in fruit fly embryos
2016
science
Science Detailed structure paves the way for more effective cancer therapies
2016
science
Science Strength of contraction determines whether cells become embryo or placenta
2016
science
Science Molecular messengers synthesised to help study how cells respond to outside stimuli
2016
science
Science New technique reveals uncharted docking sites in RNA-binding proteins
2016
science
Science Study provides insights into workings of new HIV drugs and how virus becomes resistant
2016
science
Science Core Technologies in Life Sciences (CTLS) association will be key resource for facility professionals
2016
science
Science “Like getting hold of a microscope for the first time”
2016
science
Science Collaborations shorten distance between EMBL Heidelberg, Germany, and CEITEC in Brno, Czech Republic
2016
science
Science New group leader combines physics and biology to answer the 'hows' of cell movement
2016
science
Science Studying at EMBL in Grenoble helps Japanese postdoc see her native country through different eyes
2016
science
Science How cells eliminate protein deposits that can lead to neurodegenerative disorders
2016
science
Science Establishing a programme of research, development and user services for time-resolved crystallography
2016
science
Science What's a microbiome? How on Earth do they work?
2016
science
Science Dozens of postdocs boosted their careers with a voyage aboard the Tara Oceans research schooner
2016
science
Science New method enables scientists to use light to direct where cancer cells go
2016
science
Science From shared interests at a conference to a surprising discovery
2016
science
Science Unexpected results: structure of DAPK enzyme reveals dual-purpose loop
2016
science
Science A perfect match: behaviourist Takefumi Kikusui visits the Gross group to explore animal attraction
2016
science
Science Largest-ever study of breast cancer genomes reveals new genes and mutations
2016
science
Science Stool transplants: finding the right match important, EMBL study shows
2016
science
Science How EMBL scientists are discovering and understanding the waves and rhythms inside us
2016
science
Science Florent Cipriani talks about his passion for developing beamline instrumentation
2016
science
Science EMBL PhD project puts development in a new light
2016
science
Science CrystalDirect, developed at EMBL, automates crystal preparation for X-ray analysis
2016
science
Science First detailed structural description of all the rings of nuclear pores
2016
science
Science Why does a cookie look different depending on how hungry you are? Neuroscientist Asari wants to find out
2016
science
Science Information on structure of molecule used for genome engineering yields increased efficiency
2016
science
Science Subtle genetic differences destine cells to placenta or animal, very early in embryo development
2016
science
Science How an EMBL team is making and sharing tools to explore tuberculosis protein structures
2016
science
Science Commentary in Nature Methods introduces the EMPIAR resource and gives glimpse of future developments
2016
science
Science 1st real-time video of starfish egg cell eliminating crucial structures, to ensure embryo viability
2016
science
Science New technique uses X-rays to find landmarks when combining fluorescence and electron microscopy
2016
science
Science Neural mechanisms in mouse brains indicate that we actively forget as we learn
2016
science
![A new tool for single-cell genomics helps us better understand differences between T cell populations. [Illustration: Spencer Phillips, EMBL-EBI]](https://www.embl.org/news/wp-content/uploads/2016/03/TCell_news_EMBL-e1457443531496-300x205.jpg)
Science TraCeR: new method for studying T cells opens up opportunities to explore immune responses
2016
science
Science Structural insights into how cohesin keeps DNA together during the cell cycle
2016
science
Science First detailed atlas of start points for genes expression in malaria-causing parasite
2016
science
Science “It’s a bit like drawing a picture of an intricate object just by looking at its shadow on the wall."
2016
science
Science How stem cells resist change
2016
science
Science What do cells in an embryo have in common with schools of fish, swarms of fireflies, and applauding audiences?
2016
science
Science How transcription factors interact to create a heart
2016
science
Science Plankton network linked to ocean's biological carbon pump revealed
2016
science
Science Protein screens developed at EMBL Hamburg now commercially available
2016
science
Science Hamburg collaborators analyse protein crystals inside the cells that made them.
2016
science
Science Further insights into how viral enzymes degrade the cell walls of Clostridia bacteria.
2016
science
Science New method is first to enable parallel profiling of the transcriptome and epigenome of a single cell.
2016
science
Science From initial development to a start-up company: Selective Plane Illumination Microscopy (SPIM) at EMBL.
2015
science
Science New microscope can record the first days of a mouse embryo’s life
2015
science
Science Making it easier to visualise, understand and predict how proteins combine to drive biological processes.
2015
science
Science Commonly used diabetes drug metformin impacts gut bacteria more than disease itself
2015
science
Science CryoEM solves 3D atomic structure of largest and most elusive RNA polymerase.
2015
science
Science From jumping genes to organ transplants, the non-human features that make us human.
2015
science
Science Using lasers to shed light on how tissues get into shape
2015
science
Science Embryology, genomics and bioinformatics combine to identify factors regulating mammalian pluripotency.
2015
science
Science Fibres that pull membrane to form a vesicle exert a force that’s 2500 times a yeast cell’s own weight
2015
science
Science Findings help demonstrate the evolutionary basis for allergy.
2015
science
Science Enzyme Portal makes it easier to explore all enzyme-related data in EMBL-EBI’s public resources.
2015
science
Science Evaluation of MinION™ sequencer finds performance and reliability consistently good.
2015
science
Science Study of mouse embryonic stem cells reveals new genes involved in the stem-cell regulatory network.
2015
science
Science Spaghetti-like proteins are surprisingly effective 'keys'
2015
science
Science 1000 Genomes Project pushed technologies and knowledge forward to understand what is 'normal' human genetic variation
2015
science
Science From the role of diatoms to how life evolved - scientists' pressing questions about life in the sea.
2015
science
Science Missing a gene may not be a big deal – a conclusion from global catalogue of genetic changes.
2015
science
Science A nuclear pore riddle: how can you use the same number of pieces to form two rings that fit inside each other?
2015
science
Science MASSIF-1 processes its 10,000th crystal, less than one year after the beamline became operational.
2015
science
Science Multifaceted approach reveals how brain and liver age, helps explain why ageing brain loses plasticity.
2015
science
Science New computational method to study biological signalling networks in healthy and cancer cells.
2015
science
Science Theodore Alexandrov is using mathematics to analyse the countless molecules produced by our cells.
2015
science
Science A journalist who spent six weeks aboard Tara reflects on the expedition’s extraordinary outcomes.
2015
science
Science EMBL scientists map ‘switches’ for distant control of gene expression.
2015
science
Science Collaboration between scientists reveals collaboration between lipids.
2015
science
Science Crowd sourcing initiative to predict effects of toxic compounds: results of 2013 DREAM Challenge.
2015
science
Science A mathematician who got ‘sucked in’ to biological problems, meet new team leader Theodore Alexandrov.
2015
science
Science Multidisciplinary research provides clues to new treatments for deadly form of leukaemia in children
2015
science
Science How T-cells are trained on what not to kill
2015
science
Science Iron regulatory proteins play important role in combatting infection, protecting against Salmonella.
2015
science
Science 3D structure of Oskar protein gives first molecular insight into how it functions.
2015
science
Science 3D imaging unravels COPI coat of cells' transport vesicles.
2015
science
Science Jan Korbel and colleagues publish commentary on risks and rewards of genome cloud computing.
2015
science
Science European team identify mechanism for producing piRNAs that silence jumping genes in germline cells.
2015
science
Science Behaviour of clathrin proteins, crucial for endocytosis, is clarified using new imaging techniques.
2015
science
Science A puzzling peculiarity resolved by Hamburg’s Sample Preparation and Characterisation facility.
2015
science
Science Researchers at EMBL-EBI speed up complex GWAS analyses with new method and algorithm.
2015
science
Science Cells 'dance' as they draw together during early embryo development.
2015
science
Science Decaying RNA molecules tell a story that could add more chapters to the study of ribosomes.
2015
science
Science Tara Oceans results reveal climate change insights, and a treasure trove of novel species and genes.
2015
science
Science Detailed structural study shows distantly related viruses share a common machinery for replication.
2015
science
Science EMBL scientists demonstrate that spatial constraints are a key factor in determining nucleus size.
2015
science
Science New research shows that some proteins domains can function even with big parts missing.
2015
science
Science Not all embryonic macrophages are the same, and only some are destined to become microglia.
2015
science
Science Unveiling the shape of... the 'molecular bin man' – cryoEM helps reveals p62 polymer in 3D.
2015
science
Science Stanford University biophysicist KC Huang on his collaboration with the Typas group in Heidelberg.
2015
science
Science Cooperate or compete? Microbes show us that getting along is the better choice for communities.
2015
science
Science Radiocarbon studies are helping researchers shine light on how neurons stay stable yet adaptable.
2015
science
Science Ground-breaking microscopy technique gives unprecedented insight into endocytosis.
2015
science
Science New single-cell genomics techniques bring ‘omics to evolution and development research.
2015
science
Science Coin toss inspires CorMap: a new statistical test that sidesteps need for error estimation.
2015
science
Science Go Team Genome! New method reveals genetic teamwork in drosophila genome.
2015
science
Science New fully automated technique enables scientists to chart complex protein networks in living cells.
2015
science
Science Combining three different kinds of microscopy to determine how molecules move during endocytosis.
2015
science
Science How strong does a spindle need to be? Videos put cell’s chromosome-separating machinery to the test
2015
science
Science Hamburg-led tuberculosis study demonstrates the power of collaboration.
2015
science
Science Tried and tested do's and don'ts of crowdsource writing.
2015
science
Science New way mice starve pathogens raises alternative approach to treatments for anaemia of chronic disease
2015
science
Science New microscopy-based method goes beyond gene sequencing, pinpointing the cause of disease.
2015
science
Science How repurposing non-coding elements in the genome gave rise to the great ‘mammalian radiation’.
2015
science
Science New Bar-ChIP method makes it easier to search for epigenetic marks in many samples at once
2015
science
Science First experimental proof that a key cellular machine forms by uniting pre-assembled modules.
2015
science
Science A brief history of microscopes, from van Leeuwenhoek to Betzig, Hell and Moerner.
2015
science
Science As EMBL Hamburg celebrates 40 years, we explore the past, present and future of crystallography.
2015
science
Science From using light to control brain activity to illuminating fruit fly development and mice’s sense of touch
2015
science
Science New statistical method for RNA-seq analysis creates order out of seeming chaos.
2015
science
Science New group leader Marco Marcia aims to broaden horizons while mapping molecules.
2015
science
Science Research led by Teichmann group identifies fundamental mechanism for controlling protein function.
2015
science
Science How do E.coli and similar bacteria grow safely? By using barrel-plugs as sensors.
2014
science
Science Compound that can restore the function of poorly working mitochondria, with therapeutic potential.
2014
science
Science Unprecedented detail in images of mouse neurons thanks to new SNAP-tagging microscopy technique.
2014
science
Science Genome-based insights into evolution of malaria-carrying Anopheles mosquitoes.
2014
science
Science In two months, 2.3 million diffraction images collected on new, fully automated ESRF/EMBL beamline.
2014
science
Science Largest collection of helminth genomic data ever assembled, in new open-access WormBase ParaSite.
2014
science
Science First complete picture of flu virus polymerase. A story of two decades of blood, sweat and sneezes.
2014
science
Science The important thing is forming good biological questions, says new group leader in Genome Biology.
2014
science
Science Whether it’s information or people, the art of connecting is key to new group leader Judith Zaugg
2014
science
Science EMPIAR lets researchers take a closer look at the images used to build 3D molecular structures.
2014
science
Science Unprecedented detail on HIV structure continues virus’ string of surprises.
2014
science
Science New, open repository helps researchers share computational models of disease.
2014
science
Science Kidney cancer linked to exposure to aristolochic acid, an ingredient in some herbal remedies.
2014
science
Science Like sports teams, cells can huddle to communicate in secret and organise group behaviour
2014
science
Science Growth factor IGF-1 boosts natural defence against type-1 diabetes and multiple sclerosis
2014
science
Science European Variation Archive makes it easier to explore detailed information about genetic variation.
2014
science
Science How Nobel-winning work by alumnus Stefan Hell shapes and inspires current EMBL scientists' research.
2014
science
Science From anemones to starfish, sea creatures are helping understand development, evolution and more.
2014
science
Science Flow cytometry: finding needles in haystacks
2014
science
Science From vitamin C to safe matches, a sample of notable scientists from our newest prospect member state.
2014
science
Science How plankton gets jet lagged: the same hormone governs our sleep patterns and a daily marine migration.
2014
science
Science Evolutionary surprise: notochord likely evolved from muscle, earlier than assumed.
2014
science
Science Researchers produce pristine stem cells, which can be precisely changed into clinically relevant cell types.
2014
science
Science Gibbon genome gives insights into evolution of this singing, swinging, tree-dwelling ape.
2014
science
Science RNAcentral is the first unified resource for all types of non-coding RNA data.
2014
science
Science Bronwen Aken discusses what research into the rabbit genome reveals about animal domestication.
2014
science
Science Vasa protein preserves pieces of 'enemy' DNA to help protect the genes of future generations.
2014
science
Science How a single molecule can attract and repel growing brain connections
2014
science
Science Ensembl has incorporated a vast amount of knowledge into a fully annotated reference human genome
2014
science
Science A rare form of an iron overload disorder kills pancreatic function, Heidelberg scientists find
2014
science
Science How fruit flies beat the cold, plus the value of precisely controlled experiments and detailed analysis
2014
science
Science Edward Lemke edits special issue of ChemBioChem on boom of technology for genetic code expansion
2014
science
Science Molecular switch enables viruses to destroy C.diff bacteria – potential alternative to antibiotics
2014
science
Science Marmoset genome provides insights into chimerism: data available in Ensembl genome explorer
2014
science
Science Cell biologists "underestimate the complexity" of protein interactions, says Toby Gibson.
2014
science
Science Embed chemists in biology departments, asking their own biological questions, says Carsten Schultz
2014
science
Science Surprising finding: enhancers find their targets long before activation in Drosophila embryos
2014
science
Science Surprising protein from a flu-like virus is 10 000th ESRF structure
2014
science
Science Focusing on basic research is crucial for the development of more advanced genetics techniques
2014
science
Science New ways of handling and distributing data at PDBe to tackle ever larger and more complex proteins
2014
science
Science Scientists determine the structure of auxin response factors: daisy-chains that regulate gene expression
2014
science
Science Enabling neighbours: intact genes can cause cancer when placed near "enhancing" regions of DNA
2014
science
Science Data from first ever worldwide Ocean Sampling Day will be shared via EMBL-EBI resources this autumn.
2014
science
Science Reference sheep genome, published by International Sheep Genomics Consortium, available in Ensembl
2014
science
Science A kaleidoscope of molecules is needed to clean up dead brain cells, and failure can have disastrous consequences
2014
science
Science How a DNA stretch influences face formation and contributes to common congenital malformations
2014
science
Science High-resolution structure reveals crucial interactions for HIV maturation
2014
science
Science DNA-coralling protein complex in an unexpected bind
2014
science
Science Genome Campus researchers discover that some immune cells turn themselves off by producing a steroid.
2014
science
Science The balance behind membrane changes that turn one cell into 6000 as a fruit fly embryo develops
2014
science
Science Tsetse fly genome sequenced; scientists hope to find new ways to control sleeping sickness.
2014
science
Science In many people with autism and other neurodevelopmental disorders, different parts of the brain don’t talk to each other very well. Scientists have now identified, for the first time, a way in which this decreased functional connectivity can come about. In a study published online today…
2014
science
Science What do bullies and sex have in common? Based on work by scientists at the European Molecular Biology Laboratory (EMBL) in Monterotondo, Italy, it seems that the same part of the brain reacts to both. In a study published today in Nature Neuroscience, the researchers found that – at least in…
2013
science
Science The molecular machine that makes essential components of ribosomes – the cell’s protein factories – is like a Swiss-army knife, researchers at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, and the Centro de Investigaciones Biológicas in Madrid, Spain, have found.…
2013
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Science An important step in building ribosomes – the cell’s protein factories – is like a strictly choreographed dance, scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have discovered. To build these factories, other ‘machines’ inside the cell have to…
2013
science
Science Migrating cells, it seems, cover their tracks not for fear of being followed, but to keep moving forward. Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have now shown that cells in a zebrafish embryo determine which direction they move in by effectively…
2013
science
Science Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg and Regensburg University, both in Germany, and the University of Lisboa, in Portugal, have discovered a promising potential drug target for cystic fibrosis. Their work, published online today in Cell, also uncovers a…
2013
science
Science Like a fireman who becomes an arsonist, a protein that prevents cells becoming cancerous can also cause tumours, scientists at the European Molecular Biology Laboratory (EMBL) in Grenoble, France, have discovered. The finding, published today in Nature Structural and Molecular Biology, stems…
2013
science
Science How our body processes cholesterol has a well-known impact on our health, but it turns out that another ‘fat molecule’ – or lipid – may be at the heart of some diseases which were thought to involve cholesterol. A group of proteins linked to conditions such as metabolic syndrome and some…
2013
science
Science The process cells use to ‘swallow’ up nutrients, hormones and other signals from their environment – called endocytosis – can play a crucial role in shaping the cells themselves, scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have found. The study,…
2013
science
Science It’s a parent’s nightmare: opening a Lego set and being faced with 500 pieces, but no instructions on how to assemble them into the majestic castle shown on the box. Thanks to a new approach by scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany,…
2013
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Science Although we know the tool’s general purpose, it can sometimes be difficult to tell if a specific pair of precision tweezers belongs to a surgeon or a master jeweller. It is now easier to solve similar conundrums about a type of protein that allows cells to react to their environment, thanks to…
2013
science