Genomic Data Infrastructure – integrating genomics into healthcare
Announcements, Science EMBL-EBI supports new European Commission project set to support the use of genomics in research and healthcare.
2022
announcementsscience
Unleashing the biotechnology potential of euglenoids
Announcements An ambitious project to sequence the genomes of all known species of euglenoids will drive research on biofuels and sustainable foods.
2022
announcements
BioModels competition: Showcase your model of the year
Updates from data resources Competition celebrates importance of robust theoretical modelling for systems biology
2022
updates-from-data-resources
Open Targets consortium welcomes Genentech as newest member
Announcements, Science Open Targets announces that Genentech will become the seventh partner in the drug discovery and validation consortium.
2022
announcementsscience
Open science for climate justice
Perspectives, Science Our experts discuss the importance of open science for food security and preserving global biodiversity.
2022
perspectivesscience
New molecular microscopy uncovers how breast cancer spreads
Research highlights, Science Researchers have created a tool that maps in previously unseen detail how breast cancer develops and spreads.
2022
research-highlightsscience
AlphaFold applications – a community assessment
Research highlights, Science Researchers use social media to share findings on how useful AlphaFold predictions are for different applications.
2022
research-highlightsscience
AI4LIFE: AI models for bioimaging
Announcements, Science Researchers across EMBL are helping to make artificial intelligence (AI) models for bioimaging analysis interoperable and openly available to the scientific community.
2022
announcementsscience
EMBL-EBI appoints Deputy Head of Research
Announcements Virginie Uhlmann will support the Interim Head of Research in managing the institute's computational research groups.
2022
announcements
Mapping the human brain: a global collaboration
Announcements, Science NIH BRAIN Initiative to fund brain atlases, network coordination, and knowledge sharing to explore brain function research.
2022
announcementsscience
Compare experimental and predicted structures with PDBe-KB
Updates from data resources You can now superpose AlphaFold models onto PDB structures at the touch of a button using the PDBe-KB aggregated views of proteins.
2022
updates-from-data-resources
Ensembl 108 has been released
Updates from data resources We are pleased to announce the release of Ensembl 108, and the corresponding release of Ensembl Genomes 55 featuring changes in the human default tracks, new genomes in Ensembl Plants and Ensembl Metazoa, and the addition of mitochondrial annotation for Tasmanian devil. Genome assemblies and…
2022
updates-from-data-resources
New releases: InterPro 91.0 and InterProScan 5.59-91.0
Updates from data resources We are pleased to announce the release of InterPro 91.0 and InterProScan 5.59-91.0
2022
updates-from-data-resources
ArrayExpress interface now retired
Updates from data resources Data continues to be available in BioStudies.
2022
updates-from-data-resources
Natural language processing for rapid protein annotation
Technology and innovation Over 40 million protein annotations have been added to the UniProt database using a Google Research natural language processing model.
2022
technology-and-innovation
Ardan Patwardhan and Wim Hagen receive Scientific Achievement Award
Lab Matters The Royal Microscopical Society awarded Ardan Patwardhan and Wim Hagen with Scientific Achievement Award
2022
lab-matters
Funding for researchers working on plastic recycling enzymes
Announcements, Science EMBL-EBI’s MGnify data resource helps researchers find enzymes for novel applications.
2022
announcementsscience
Biodiversity Genomics Europe: addressing biodiversity loss through genomics
Announcements, Science European experts gather to launch a project that aims to characterise and conserve life on Earth using DNA data.
2022
announcementsscience
Ardan Patwardhan receives Scientific Achievement Award
Announcements The Royal Microscopical Society recognises Ardan Patwardhan’s contributions to the field of electron microscopy.
2022
announcements
European institutes commit to data access across borders
Announcements, Science The Federated EGA is set to improve access to sensitive human data in a safe and secure way.
2022
announcementsscience
In tribute to Her Majesty Queen Elizabeth II
Announcements The United Kingdom is a founding member of EMBL, and has hosted EMBL’s European Bioinformatics Institute since 1994. We recognise that the passing of Her Majesty Queen Elizabeth II will have a profound impact on the country, and we extend our deepest sympathies to the Royal Family at this…
2022
announcements
AlphaFold: where will the next AI breakthrough come from?
Perspectives, Science Ewan Birney, Deputy Director General of EMBL and Director of EMBL-EBI, reveals the key factors that enabled AlphaFold to change the world of biology.
2022
perspectivesscience
Molecules to Ecosystems: Virginie Uhlmann on the Theory transversal theme
Lab Matters Virginie Uhlmann, Research Group Leader at EMBL-EBI and one of the co-chairs of the Theory@EMBL transversal theme, chats about how this theme will open up new research avenues.
2022
lab-matters
CNest: a new method for copy number variation analysis
Research highlights, Science A new method for the robust analysis of copy number variation and used UK Biobank data to identify links between genome and disease.
2022
research-highlightsscience
New antibiotic resistance genes identified in tuberculosis
Research highlights, Science International consortium analyses the genetic sequences and antibiotic susceptibility of 10,000 global Mycobacterium tuberculosis isolates.
2022
research-highlightsscience
New releases: InterPro 90.0 and InterProScan 5.57-90.0
Updates from data resources InterPro version 90.0 and InterProScan 5.57-90.0 are now available. InterPro now features hundreds of new methods integrated from partner databases, and InterProScan draws on over 40000 entries
2022
updates-from-data-resources
Shining a light on how bacteria interact
Research highlights, Science Machine learning has helped researchers uncover new insights into how bacteria infect host cells.
2022
research-highlightsscience
AlphaFold predicts structure of almost every catalogued protein known to science
Science, Technology and innovation AlphaFold database offers a look at 3D protein universe.
2022
sciencetechnology-and-innovation
Latvian science benefits from prospect membership
Events The first meeting of the Latvian Bioinformatics Forum points towards an even brighter future for the country’s role in European life sciences
2022
events
Uncharted territories in the human genome
Research highlights, Science Scientists identify previously unexplored gene segments to be added to human genome databases.
2022
research-highlightsscience
Ensembl 107 has been released
Updates from data resources The Ensembl 107 release contains updates to regulatory annotations and updated vertebrate and metazoan species.
2022
updates-from-data-resources
Interactive data visualisation for Single Cell Expression Atlas
Updates from data resources Using powerful data visualisation and interactive search results across datasets allows users to explore hypotheses across a range of metadata, and discover new insights backed by expertly curated, consistently reanalysed single cell sequencing data. Searching for metadata, allows a powerful…
2022
updates-from-data-resources
Darwin Tree of Life at the Royal Society Summer Science Exhibition
Announcements A closer look at how genome sequencing is helping us protect biodiversity and our latest public engagement activities
2022
announcements
UKRI allocates funding for EMBL-EBI data resources
Announcements Funding set to support data resources for key areas of antimicrobial resistance, sustainable agriculture and biodiversity loss
2022
announcements
ArrayExpress interface to close
Updates from data resources On 30 September 2022 the ArrayExpress interface will close. All datasets have now been migrated from ArrayExpress into the BioStudies ArrayExpress collection
2022
updates-from-data-resources
Supporting the African BioGenome Project to build bioinformatics capacity
Announcements, Lab Matters The African BioGenome Project and EMBL have signed a Memorandum of Understanding to support each other in building genomics and bioinformatics capacity across Africa
2022
announcementslab-matters
New computational biology training in hematology
Announcements Tapping the potential of computational biology and bioinformatics to understand blood-related diseases.
2022
announcements
Impact of DNA mutations on blood cell production uncovered
Research highlights, Science Researchers discover how DNA mutations change blood cell production and how this relates to ageing and cancer development.
2022
research-highlightsscience
A machine learning approach for allocating gene function
Science, Technology and innovation Researchers in the Ensembl team are making the most of machine learning methods to speed up genome annotation pipelines
2022
sciencetechnology-and-innovation
Fergal Martin – Eukaryotic Annotation Team Leader
Lab Matters Fergal Martin discusses the importance of open access data and his work in different biodiversity initiatives
2022
lab-matters
Organisations should embrace open science faster – interview with Prof. Dame Janet Thornton
Lab Matters, Perspectives Janet Thornton, the inaugural winner of the FEBS Journal Open Science Award, explains the importance and impact of open science.
2022
lab-mattersperspectives
Europe PMC: Harnessing the power of text mining to accelerate life sciences research
Science, Technology and innovation How text mining collaborations benefit our research, data resources, and the wider scientific community.
2022
sciencetechnology-and-innovation
2.4 billion sequences now available in the latest MGnify protein database release
Updates from data resources 2.4 billion protein sequences are now available in the latest MGnify release including new annotations provided by Google AI
2022
updates-from-data-resources
Peter Harrison – Genome Analysis Team Leader
Lab Matters Peter Harrison discusses the importance of data accessibility and his passion for biodiversity and agricultural genomics.
2022
lab-matters
Predicted complexes from ModelArchive now on PDBe-KB pages
Updates from data resources New dataset of predicted protein complexes accessible through 3D-Beacons Network.
2022
updates-from-data-resources
Greater than the sum of our genes: DNA does not define us
Lab Matters, Perspectives Ewan Birney discusses the input of both genetics and our environment in making us who we are
2022
lab-mattersperspectives
Guy Cochrane appointed Executive Director of Global Biodata Coalition
Announcements The GBC is a coalition of life sciences and biomedical research funders that aims to optimise the funding and management of biodata resources worldwide. The organisation has two priority aims: to better coordinate and share approaches for efficient management and growth of the biodata…
2022
announcements
The MANE collaboration: working together to support genome science
Research highlights, Science Researchers from the MANE collaboration bring you the most comprehensive human genome annotation dataset to date.
2022
research-highlightsscience
Welcome: John Lees
Lab Matters John Lees joins EMBL-EBI as a Group Leader in Pathogen informatics and modelling.
2022
lab-matters
Latest Release of the Single Cell Expression Atlas
Updates from data resources The latest Single Cell Expression Atlas (SCEA) release is here and features collaborations with DiscovAIR and the Fly Cell Atlas
2022
updates-from-data-resources
Genomic sequencing aids the global Tuberculosis fight
Perspectives, Science Zamin Iqbal and his team are working with researchers all over the globe to help put a stop to Tuberculosis
2022
perspectivesscience
Darwin Tree of Life at EMBL-EBI: reaching the first major milestone
Announcements, Science Our researchers highlight their contributions to the Darwin Tree of Life project and how new genome annotations helps to further biodiversity research
2022
announcementsscience
Safeguarding African biodiversity through genomics
Perspectives, Science The African BioGenome Project aims to safeguard biodiversity and build bioinformatics capacity across Africa
2022
perspectivesscience
Deep learning models help predict protein function
Perspectives, Science Deep learning models can improve protein annotations and has helped expand the Pfam database.
2022
perspectivesscience
New genetic data policy must promote biodiversity conservation
Announcements, Science Scientists urge the adoption of a sensible international policy for digital sequence information.
2022
announcementsscience
Pfizer joins the Open Targets consortium
Announcements, Science Open Targets, a consortium focused on drug target identification, prioritisation, and validation, announced today that Pfizer has joined as a partner.
2022
announcementsscience
Learning from Deep Learning: the inspirational story behind AlphaFold
Science DeepMind visits EMBL Heidelberg to discuss current and future implications of Artificial Intelligence for life science research.
2022
science
AlphaFold update – neglected tropical diseases
Updates from data resources Latest AlphaFold database update adds 27 new organisms and almost 200,000 new protein structure predictions relevant to neglected tropical diseases and antimicrobial resistance
2022
updates-from-data-resources
Genomic data for biodiversity – a global challenge
Perspectives, Science An exploration of where in the world genomics methods are applied and where the data are used.
2022
perspectivesscience
The Earth Biogenome Project: on track and ready to ramp up
Announcements, Science On track to reach an ambitious goal of 3,000 genomes sequenced by the end of 2022, what’s next for the Earth Biogenome Project?
2022
announcementsscience
Welcome: Melissa Harrison
Lab Matters Melissa Harrison joins EMBL-EBI as the new Team Leader of Literature Services. We found out more about her plans for open access publishing and Europe PMC.
2022
lab-matters
Can data help feed a hungry world?
Science How genomics, open data, and multidisciplinary science can improve food security.
2021
science
DUO: streamlining access to biomedical datasets
Science The GA4GH Data Use Ontology (DUO) supports a data authorisation and access framework to streamline consent to use biomedical data
2021
science
Making sense of bacterial DNA data
Science A vast, curated collection of bacterial genomes is now organised, searchable and open to the community.
2021
science
Open data on the rise: the value of EMBL-EBI data resources
Lab Matters Independent study reveals that EMBL-EBI open data resources are critical for the life sciences.
2021
lab-matters
BY-COVID – a new EU project for pandemic preparedness
Science The BY-COVID project aims to make infectious disease data, including COVID-19, openly available to everyone.
2021
science
CRyPTIC: cataloguing drug resistance mutations in M. tuberculosis
Science Profiling M. tuberculosis strains from 27 countries to reveal causes of drug resistance.
2021
science
The human genome, data sharing, and drug discovery: a career profile with Ian Dunham
Lab Matters Ian Dunham walks us through his career so far including working on the human genome project, seeing his work on the cover of Nature and his current role as Director of Open Targets.
2021
lab-matters
Genomic tracking of the COVID-19 pandemic in England
Science Largest in-depth analysis of genomic data tracks the spread of SARS-CoV-2 lineages in England.
2021
science
DeepMind and EMBL release the most complete database of predicted 3D structures of human proteins
Science Partners use AlphaFold, the AI system recognised last year as a solution to the protein structure prediction problem, to release more than 350,000 protein structure predictions including the entire human proteome to the scientific community.
2021
science
Accessible 3D protein models to accelerate scientific discovery
Science DeepMind and EMBL-EBI to make millions of protein structure predictions freely available to the scientific community.
2021
science
Great expectations – the potential impacts of AlphaFold DB
Science A discussion of the applications that AlphaFold DB may enable and the possible impact of the resource on science and society.
2021
science
Welcome: Sarah Dyer
Lab Matters EMBL welcomes Sarah Dyer, the new Non-Vertebrate Genomics Team Leader at EMBL-EBI.
2021
lab-matters
Visualising RNA structures using R2DT
Science New software enables scientists to visualise RNA secondary structures using the world’s largest RNA structure dataset.
2021
science
EMBL scientists elected as EMBO Members
Lab Matters John Marioni, Alex Bateman, and Takashi Hiiragi have been elected to EMBO Membership.
2021
lab-matters
EMBL scientists support malaria research
Science EMBL scientists support research on malaria by providing freely available data resources and using innovative experimental approaches. Our Course and Conference Office facilitates the exchange of knowledge in the field by hosting the annual BioMalPar conference.
2021
science
Just the gist: Big data and pandemics in seven key points
Events EMBL’s most recent Science and Society seminar explored how best to harness big data to address multi-faceted issues of a pandemic.
2021
events
Piecing together the best reference genome
Science Researchers reveal the best technology for assembling reference genomes.
2021
science
Uniting strengths to expand research
Lab Matters The European Molecular Biology Laboratory and the Italian Institute of Technology have signed an agreement to expand the scope of their collaboration to include areas of mutual interest and in the context of EMBL’s 2022-2026 Programme “Molecules to Ecosystems”.
2021
lab-matters
Using metagenomic techniques to explore lichens
Science Researchers have used a metagenomics approach to piece together the genomes of yeasts found in wild lichens.
2021
science
Repurposing drugs to manage COVID-19 progression
Science Researchers use large-scale human genetic studies to identify drug targets important for managing COVID-19 in its early stages
2021
science
Linking genetics and age-related diseases
Science Researchers have used human medical and genetic data from UK Biobank to investigate the genetics of age-related diseases
2021
science
Pfam releases structures for every protein family
Science Thousands of new protein structure models, prected using deep learning, now available to explore
2021
science
Allyship and support: an interview with Janet Thornton
Lab Matters Professor Dame Janet Thornton discusses work–life balance, the support she has received during her career, and how organisations can help staff during the COVID-19 pandemic
2021
lab-matters
Finding coronavirus’s helper proteins
Science A team of EMBL scientists and colleagues have analysed how the novel coronavirus affects proteins in human cells. They identified several human proteins as potential drug targets to prevent viral replication.
2021
science
Insights into the new B.1.1.7 coronavirus lineage
Science A new lineage of coronavirus was first identified in the UK, but why is it spreading much more rapidly within the population?
2021
science
Monitoring dangerous bacteria in freshwater
Science Freshwater sports can cause waterborne infections, but real-time DNA sequencing could help.
2021
science
Discover the wonderful world of proteins: first virtual PDB Art exhibition
Lab Matters Schoolchildren create exquisite protein-inspired artworks
2020
lab-matters
Solving the protein structure puzzle
Science How artificial intelligence can help us solve the mysteries of the protein universe
2020
science
Microbiomes help predict the future of the Atlantic
Science Microbiomes, plastics, and connectivity – AtlantECO aims to understand the fabric of the Atlantic Ocean.
2020
science
EOSC: shaping Europe’s digital future
Lab Matters EMBL’s Rupert Lück is engaged in developing the European Open Science Cloud (EOSC): the infrastructure that will support the future of data sharing and analysis in Europe.
2020
lab-matters
Repurposing drugs for a pan-coronavirus treatment
Science Scientists from the Beltrao Group at EMBL-EBI and collaborators identified drug targets common to SARS-CoV-2, SARS-CoV-1, and MERS-CoV, three pathogenic coronaviruses. They also found potential drugs that could be repurposed as COVID-19 treatments, and against emerging coronavirus strains in the…
2020
science
Genome sequencing accelerates cancer detection
Science The Gerstung Group at EMBL-EBI and collaborators have developed a statistical model that analyses genomic data to predict whether a patient has a high or low risk of developing oesophageal cancer.
2020
science
Welcome: Geetika Malhotra
Lab Matters The Web Development team provides a central source of web design and development for EMBL’s European Bioinformatics Institute (EMBL-EBI). In July, Geetika Malhotra joined the team as their new Head.
2020
lab-matters
New clues to a 500-year old mystery about the human heart
Science An international team of scientists involving Ewan Birney's group has investigated the function of a complex mesh of muscle fibres that line the inner surface of the heart.
2020
science
The curious genome of the tuatara, an ancient reptile in peril
Science A global team of researchers including the Flicek Team at EMBL-EBI has partnered up with the Māori tribe Ngātiwai to sequence the genome of the tuatara, a rare reptile endemic to New Zealand.
2020
science
Bagpipe and Pokemon, or how not to name a human gene
Science The human genome harbours about 19 000 protein-coding genes, many of which still have no known function. As scientists unveil the secrets of our DNA, they come across novel genes that they need to refer to using a unique name. The Human Genome Organisation’s Gene Nomenclature Committee (HGNC) at…
2020
science
Artificial intelligence finds patterns of mutations and survival in tumour images
Science Researchers have developed an artificial intelligence algorithm that uses computer vision to analyse tissue samples from cancer patients. The algorithm can distinguish between healthy and cancerous tissues, and can also identify patterns DNA and RNA changes in tumours.
2020
science
Unparalleled inventory of the human gut ecosystem
Science An international team of scientists has collated all known bacterial genomes from the human gut microbiome into a single large database. Their work will allow researchers to explore the links between bacterial genes and proteins, and their effects on human health.
2020
science
Funding to predict the risk of infectious disease outbreaks
Lab Matters European collaboration receives funding to explore risks and impact of future infectious disease outbreaks.
2020
lab-matters
Applications for virtual learning lab open
Lab Matters The European Learning Laboratory for the Life Sciences (ELLS), EMBL’s education facility, invites secondary school science teachers to participate in a virtual training course this autumn entitled ‘Introducing your microbiome’.
2020
lab-matters
Two EMBL scientists become EMBO Members
Lab Matters This year, EMBO elected 63 new members, including Alexander Aulehla, Group Leader and Senior Scientist at EMBL Heidelberg, and Paul Flicek, Associate Director of EMBL-EBI Services, Senior Scientist, Group and Team Leader at EMBL-EBI.
2020
lab-matters
Welcome: Ellie McDonagh
Lab Matters Open Targets welcomes new Informatics Science Director
2020
lab-matters
Five things you probably didn’t know about the Human Genome Project
Science Today we celebrate the 20th anniversary of the first draft of the entire human genome.
2020
science
Unpicking the complexity of DNA mutations
Science DNA damage caused by chemical mutagens is not repaired immediately and can create more genetic diversity in tumours.
2020
science
Distinguishing coronavirus genome mutations from inadvertent errors
Science EMBL scientists have performed a large-scale analysis of over 4700 SARS-CoV-2 genome sequences. They found that many of the most interesting changes in the SARS-CoV-2 genome that have been reported so far are likely to be technical artefacts, rather than biological mutations.
2020
science
DNA damage and faulty repair jointly cause mutations
Science DNA mutations are caused by a combination of DNA damage and repair, shows study by EMBL-EBI and collaborators.
2020
science
EMBL-EBI launches COVID-19 Data Portal
Science The new collaborative space will help scientists, public health and healthcare professionals around the world to fight the coronavirus pandemic.
2020
science
EMBL-EBI leads International collaboration to share COVID-19 research data
Science EMBL-EBI set to launch European COVID-19 Data Platform to help store, share, and analyse research data linked to the COVID-19 pandemic.
2020
science
Snowy day
Picture of the week Colder winter weather has finally arrived EMBL-EBI. It’s the first time the site has seen snow this winter.
2020
picture-of-the-week
Luxembourg funds research collaborations with EMBL
Lab Matters 2020 call now open for FNR funding of bilateral projects between EMBL and Luxembourg
2020
lab-matters
Pinpointing rare disease mutations
Science New resource that categorises genes essential for supporting life could be used to identify rare disease mutations
2020
science
Ageing and disease
Events Dame Janet Thornton presents the 2019 EMBL Insight Lecture: Ageing and disease – what is the link?
2020
events
Machine learning finds critical phosphosites
Science Resource has implications for disease research
2019
science
Science date: The Crick meets EMBL
Science Crick and EMBL PhDs talk science over coffee
2019
science
Convention on the Rights of the Child stored in DNA
Science Children's rights stored in synthetic DNA
2019
science
Microbiomes take the stage at New Scientist Live
Events On microbiomes, public engagement and not being boring
2019
events
A tool to monitor tuberculosis
Science Funding awarded to EMBL-EBI for tuberculosis monitoring tool
2019
science
Science for everyone
Events During the Nacht der Forschung 2019, everyone was able to become a scientist for a day at EMBL
2019
events
B cells linked to immunotherapy
Science Immunotherapy: the role of B cells
2019
science
25 years of EMBL-EBI
Events EMBL-EBI celebrated its 25 anniversary on 1 September 2019
2019
events
Welcome: Isidro Cortés-Ciriano
Science Exploring the cancer genomics labyrinth
2019
science
Where science meets art
Picture of the week The most basic building blocks of life are the biological molecules in our cells. While these molecules are too small to see with most microscopes, they have incredibly complex and beautiful structures. Therefore, the Protein Data Bank in Europe (PDBe), The Art Society CANTAB and The Art Society…
2019
picture-of-the-week
Understanding molecular mechanisms of ageing
Science Understanding how ageing works at a molecular level
2019
science
Exploring the beauty of proteins
Science Schoolchildren get creative with 3D protein structures
2019
science
New Directors and Associate Directors
Lab Matters Promotions for Anne Ephrussi, Rainer Pepperkok, Paul Flicek and Jo McEntyre
2019
lab-matters
Programming: language
Science How computer processing of human language is harnessed by EMBL scientists
2019
science
Fun with fern photography
Alumni EMBL alumna Jennifer Deegan built a prize-winning system for photographing ferns
2019
alumni
Use your coding superpowers for good
Lab Matters Setting up a kids coding club - where to start
2019
lab-matters
A new home for biological images
Science The BioImage Archive - EMBL-EBI's first dedicated imaging data resource
2019
science
EIPOD4: 2019 applications are open
Lab Matters EIPOD4 will prepare researchers for the increasing interdisciplinarity of scientific career paths
2019
lab-matters
How coding opens up scientific data
Science The increasing importance of code in the biological sciences
2019
science
Life with the endangered kākāpō
Science Using genomics to help endangered species
2019
science
A colourful day at EMBL-EBI
Picture of the week EMBL is an intergovernmental organisation, currently supported by 26 member states, one prospect and two associate member states. There are more than 1700 people working at EMBL, who come from more than 80 countries, creating a multicultural environment. EMBL also operates from six sites in Europe:…
2019
picture-of-the-week
EMBL joins Tara stopovers in London and Hamburg
Events Tara schooner welcomes on board journalists, policymakers, funders and scientists
2019
events
Building engagement
Lab Matters The team at ELLS use Lego to teach children the fundamentals of DNA.
2019
lab-matters
Top tips for teaching yourself to code!
Lab Matters Overwhelmed as a biologist getting to grips with computer programming? EMBLers are here to help!
2019
lab-matters
A fiery end to a productive day
Picture of the week EMBL’s sites provide spectacular views, such as this fiery sunset at the Wellcome Genome Campus in Hinxton. The campus, in the heart of the Cambridgeshire countryside, is home to several institutes and organisations working on genomics and computational biology. Among them is EMBL’s European…
2019
picture-of-the-week
Welcome: Jessica Vamathevan
Lab Matters Building bonds between academia and industry
2019
lab-matters
Prioritising cancer drug targets using CRISPR
Science Large CRISPR screen prioritises hundreds of promising genes for personalised cancer treatment
2019
science
Comprehensive protein data for drug development
Lab Matters PDBe-KB - new data resource for protein structure and function launches
2019
lab-matters
Understanding early embryo development in mice
Science How organs form in a mouse embryo
2019
science
Almost 2000 unknown gut bacteria discovered
Science Researchers identify novel gut bacteria species and call for more data from beyond Europe and North America
2019
science
More than 100 new gut bacteria discovered in human microbiome
Science A new database of bacteria in the human microbiome is the most comprehensive to date.
2019
science
The web meets genomics: a DNA search engine for microbes
Science New search engine allows researchers to identify antibiotic resistance genes or mutations in real time
2019
science
Funding for bioinformatics technical infrastructure
Lab Matters Enhancing the world's bioinformatics infrastructure
2019
lab-matters
Most popular articles of the year: 2018
Lab Matters A collection of the most read articles from the EMBL news website in 2018
2019
lab-matters
Facilitating transcontinental human data exchange
Science Federated data sharing will now be possible on an unprecedented scale
2019
science
Edith Heard starts as Director General of EMBL
Lab Matters On January 1 2019, Edith Heard takes up the position of EMBL’s Director General
2019
lab-matters
Discovering new enzymes just got easier
Science EMBL-EBI industry case study: Biocatalysts
2018
science
Night of research, culture and treats
Events The EMBL Teens reporters discover the European Researchers’ Night
2018
events
Algorithm identifies gene–environment relationships
Science New algorithm will enhance understanding of relationship between genotype and environmental factors
2018
science
Welcome: Sarah Butcher
Lab Matters Building bridges between scientists and software developers
2018
lab-matters
An in silico hope for biology: machine learning
Lab Matters How EMBL scientists are using machine learning to advance biology
2018
lab-matters
Genomes of all known UK species to be sequenced
Science Genomes of 66,000 UK species to be sequenced in global effort to sequence all known eukaryotic species
2018
science
Sanofi joins Open Targets
Lab Matters Pharmaceutical company Sanofi strengthens drug targets discovery collaboration Open Targets
2018
lab-matters
PhenoMeNal: an online portal for metabolomics
Science Complex metabolomics analyses in the cloud
2018
science
Art meets structural biology
Science The Protein Data Bank in Europe celebrates its schools art project with its largest exhibition yet
2018
science
Europe PMC now indexes preprints
Science Europe PMC adds preprints to its search
2018
science
Leukaemia roots detectable years before diagnosis
Science Acute myloid leukaemia risk could be detected years before diagnosis
2018
science
Personalised medicine: one data type is not enough
Science New computational method uses multi-omics analysis for personalised medicine
2018
science
EMBL in six objects
Lab Matters A history of EMBL in six objects from the EMBL Archive
2018
lab-matters
A pint of EMBL science
Events EMBL and Pint of Science join forces to entertain and educate
2018
events
How wild species may benefit from mouse genetic data
Science Of mice and gorillas: using mouse data for conservation
2018
science
PhD goals: why not start a company?
Lab Matters EMBL-EBI PhD student launches start-up focusing on epigenetics and wellbeing
2018
lab-matters
20 years of building teams and sites
Alumni Mark Green, EMBL-EBI’s Head of Administration reflects on his time at the institute
2018
alumni
Celgene joins Open Targets
Lab Matters New partner strengthens drug discovery collaboration
2018
lab-matters
New insights into the origins of cancer
Science What worms can tell us about cancer
2018
science
PDX Finder – Free global portal for cancer models
Science Launch of the first free global online catalogue of PDX models
2018
science
New method probes gene expression by cell location
Science What does a cell's location tell us?
2018
science
The genetic risk factors for depression
Science Is depression in your genes?
2018
science
Insights into early cell life
Science New technique offers insight into early cell life
2018
science
Humans of EMBL: Past lives
Lab Matters Discover the past lives and journeys that brought people to EMBL
2018
lab-matters
Study identifies new diabetes genes
Science Network of genes linked to development of diabetes
2018
science
EMBL’s first wetlab e-learning courses go live
Events EMBL’s training programme launches its first e-learning courses: introductions to optogenetics and CLEM
2018
events
Belgian PhD student decodes DNA and wins a Bitcoin
Science Nick Goldman of EMBL-EBI issued a challenge in 2015. In 2018, a winner emerged just in time.
2018
science
Your favourite reads of 2017
Lab Matters A look back at some of the most read stories on EMBL’s news website this year
2017
lab-matters
The future of training
Events EMBL experts outline the trends shaping scientific training in the coming years
2017
events
Exploring 3D macromolecules in a flash
Science High resolution 3D protein structures in a giffy with PDBe
2017
science
Takeda joins drug target discovery initiative
Lab Matters Takeda joins pioneering public-private drug discover collaboration Open Targets
2017
lab-matters
BioModels performance boost, new model formats
Science New BioModels infrastructure supports significantly more model formats and offers improved search
2017
science
Humans of EMBL: Curiosity
Lab Matters EMBLers across all sites share how their curiosity about the world shapes their everyday life
2017
lab-matters
How malaria springs to action in mosquitoes
Science Insights into the reproduction of Plasmodium parasites in mosquitoes reveal rapid and broad activity
2017
science
Obituary: Fotis Kafatos
Alumni Former EMBL Director General Fotis Kafatos passes away
2017
alumni
A smart cabinet of curiosities
Science How open data is changing our pursuit of discovery
2017
science
Welcome, Andrew Leach
Science Q&A with EMBL-EBI's Head of Chemical Biology data services
2017
science
Ten years of training at EMBL-EBI
Events International experts gather at EMBL-EBI to reflect on the future of bioinformatics training
2017
events
Computational models of cancer available
Science How patient-derived computational models can help researchers understand cancer
2017
science
Welcome: Zamin Iqbal
Science The Iqbal research group hopes to build a 'Google of bacteria' to help better interpret the genome
2017
science
Bioinformatics in Latin America
Lab Matters EMBL-EBI supports bioinformatics training and capacity in Latin America
2017
lab-matters
UK Biobank partners with the EGA
Science Genetic data from a major cohort now distributed via EMBL-EBI
2017
science
How bacteria affect your wellbeing
Events Science and Society event answers controversial questions about gut microbes
2017
events
The sexual dimorphism dilemma
Science IMPC explains how much the sex of animals is misdirecting research results
2017
science
Mouse genes could help decipher disease
Science EMBL-EBI and IMPC characterised over 3000 mouse genes, revealing new gene associations with disease
2017
science
Open imaging data for biology
Science The Image Data Resource - prototype of the first open repository linking imaging and molecular data
2017
science
Senses: Silencing noise
Science Two EMBL researchers are exploring new ways to filter out noise and get to the data they need
2017
science
Embryos use ancient viral DNA
Science EMBL scientists detect important function of genetic sequence our ancestors assimilated from a virus
2017
science
Ageing: cell coordination breakdown
Science Researchers use single-cell sequencing to understand how cells age
2017
science
Obituary: Anna Tramontano
Lab Matters Anna Tramontano, bioinformatics pioneer and EMBL alumna, has passed away
2017
lab-matters
A tribute to Anna Tramontano
Lab Matters Janet Thornton reflects on the contributions of EMBL alumna Anna Tramontano
2017
lab-matters
Women in science: Glass half full?
Lab Matters Ottoline Leyser on the fallacy of failure and the road to self-determination
2017
lab-matters
Building bioinformatics capacity in Africa
Alumni EMBL alumna Nicola Mulder reflects on her pan-African bioinformatics project and its impact
2017
alumni
New EMBL and GSK collaboration
Lab Matters GSK and EMBL have signed an agreement to enhance understanding of disease and drug mechanisms
2017
lab-matters
Genetic switches can change shape
Science EMBL scientists discovered that common mutations can change the shape of gene promoters
2017
science
Omnipath for signalling pathways
Science New method combines signalling pathway data resources to improve systems biology research
2016
science
BLUEPRINT project delivers
Science BLUEPRINT: EMBL-EBI and the push to decipher the blood epigenome
2016
science
Improving data analysis in imaging mass spec
Science Open source bioinformatics method for finding metabolites makes experiments comparable across labs
2016
science
Collaboration is beautiful
Science Where design meets bioinformatics, new scientific perspectives abound.
2016
science
Drivers of evolution hidden in plain sight
Science A rapid, versatile mechanism that modifies proteins is revealed to be crucial for the evolutionary process
2016
science
EMBL-EBI hosts the Cambridge New Therapeutics Forum
Events CamNTF hosts meetings around Cambridge, open to all scientists interested in new therapeutics
2016
events
‘Essential genes’ help focus research
Science IMPC study identifies 410 genes essential to life in the mouse, providing a window on human disease
2016
science
See data in a new light
Science 3D printing, gaming, virtual reality and lenticular posters bring new perspectives to research
2016
science
Postdocs of EMBL
Lab Matters Turning the spotlight on the diverse universe of EMBL’s 200-strong postdoc community
2016
lab-matters
Form follows function
Science 'The PDB plays a crucial role in structural biology research and development'
2016
science
Just try!
Lab Matters German students visit EMBL-EBI on a tour to explore a new culture and different career paths
2016
lab-matters
Mapping early development
Science “Like getting hold of a microscope for the first time”
2016
science
Making business in Britain
Alumni Abel Ureta-Vidal and Louise Modis join colleagues and peers at gathering of UK-based alumni
2016
alumni
Towards personalised breast cancer treatment
Science Largest-ever study of breast cancer genomes reveals new genes and mutations
2016
science
Foetus, or placenta?
Science Subtle genetic differences destine cells to placenta or animal, very early in embryo development
2016
science
Supporting the bioimaging revolution
Science Commentary in Nature Methods introduces the EMPIAR resource and gives glimpse of future developments
2016
science
![A new tool for single-cell genomics helps us better understand differences between T cell populations. [Illustration: Spencer Phillips, EMBL-EBI]](https://www.embl.org/news/wp-content/uploads/2016/03/TCell_news_EMBL-e1457443531496-300x205.jpg)
Immunology meets single-cell sequencing
Science TraCeR: new method for studying T cells opens up opportunities to explore immune responses
2016
science
Leading the way for gender equality
Lab Matters Award acknowledges leadership in gender equality on the Wellcome Genome Campus
2016
lab-matters
DREAM shadows: chasing down disease networks
Science “It’s a bit like drawing a picture of an intricate object just by looking at its shadow on the wall."
2016
science
What is the value of open data?
Lab Matters Independent analysis of EMBL-EBI underscores the value and impact of open data in the life sciences
2016
lab-matters
Linking DNA modification and gene expression
Science New method is first to enable parallel profiling of the transcriptome and epigenome of a single cell.
2016
science
What’s on in 2016
Events With 28 conferences and 57 courses, 2016 will be EMBL’s most eventful year to date.
2015
events
Bioinformatics training in Africa
Events GOBLET initiative supports pan-African bioinformatics trainers in Cape Town.
2015
events
Periodic table of protein complexes
Science Making it easier to visualise, understand and predict how proteins combine to drive biological processes.
2015
science
Target Validation platform launches
Lab Matters Identifying evidence-based relationships between drug targets and diseases.
2015
lab-matters
BioBeat15: Translating genomics into biobusiness
Events Connecting entrepreneurs and world leaders in genomics to address opportunities and challenges.
2015
events
Humans of EMBL
Lab Matters Compelling short stories that shine light on the life and work of EMBL staff.
2015
lab-matters
EMBL in pictures
Events A snapshot of the many activities and events that took place in the world of EMBL this Autumn.
2015
events
Unpacking embryonic pluripotency
Science Embryology, genomics and bioinformatics combine to identify factors regulating mammalian pluripotency.
2015
science
Allergy: the price of immunity?
Science Findings help demonstrate the evolutionary basis for allergy.
2015
science
Enzyme research made easier
Science Enzyme Portal makes it easier to explore all enzyme-related data in EMBL-EBI’s public resources.
2015
science
Mini DNA sequencer tests true
Science Evaluation of MinION™ sequencer finds performance and reliability consistently good.
2015
science
Finding links and missing genes
Science Missing a gene may not be a big deal – a conclusion from global catalogue of genetic changes.
2015
science
Symposium sails sea of knowledge
Events Insights from organisers of upcoming EMBO|EMBL Aquatic Microeukaryotes symposium.
2015
events
EMBL-EBI training news
Events Highlights from EMBL-EBI’s Training Programme: Open Day, revamped webpages, free webinar series.
2015
events
![Tara expeditions docks in London, September 2015, on its way to the UN Climate Change Conference in Paris. [PHOTO: Robert Slowley]](https://www.embl.org/news/wp-content/uploads/2015/09/1509-tara-london-ib-300x206.jpg)
EMBL onboard Tara, London 2015
Events Tara Oceans research vessel welcomes aboard scientists, policymakers and funders.
2015
events
Clearing a path for cancer research
Science New computational method to study biological signalling networks in healthy and cancer cells.
2015
science
From packets to planets
Events Insights from the evangelical Vint Cerf, a “founding father of the Internet”, during a visit to EMBL.
2015
events
Welcome: Moritz Gerstung
Lab Matters New group explores why patients with same cancer exhibit unique constellations of genetic mutations.
2015
lab-matters
Transitions
Lab Matters Janet Thornton reflects on her time as Director of one of Europe’s fastest growing research institutes.
2015
lab-matters
An ocean odyssey
Science A journalist who spent six weeks aboard Tara reflects on the expedition’s extraordinary outcomes.
2015
science
EIPOD goes cubic
Lab Matters EI3POD: flagship interdisciplinary postdoc programme opens its doors to academia and industry.
2015
lab-matters
One from Many
Lab Matters Database administrator's photo essay reflects internationality and personality of the Genome Campus.
2015
lab-matters
Janet Thornton steps down
Lab Matters Staff gather to celebrate Janet Thorton's 14 years as Director of EMBL-EBI.
2015
lab-matters
Pandemic! A public event
Events EMBL-EBI organises an evening of talks and discussion about the global spread of infectious disease.
2015
events
Large-scale genetic analysis made easier
Science Researchers at EMBL-EBI speed up complex GWAS analyses with new method and algorithm.
2015
science
Open access: transforming science
Lab Matters EMBL’s new open access policy aims to make EMBL research widely and freely accessible.
2015
lab-matters
EMBL-EBI joins CERN openlab
Lab Matters CERN openlab enters a new phase, expanding to include EMBL-EBI and other public research organisations.
2015
lab-matters
Why you need an ORCID
Lab Matters Jenny Cham blogs about how ORCID helps distinguish her from all the other Jenny Chams in the world.
2015
lab-matters
A powerful HMMER for data mining
Lab Matters HMMER – a fast, sensitive search tool – helps find sequence relationships deep in evolutionary time.
2015
lab-matters
ELIXIR accelerates
Lab Matters ELIXIR receives major Horizon 2020 funding to ‘EXCELERATE' activities over the next four years.
2015
lab-matters
Oceans endeavour charts 40 million genes
Science Tara Oceans results reveal climate change insights, and a treasure trove of novel species and genes.
2015
science
Are protein domains indivisible?
Science New research shows that some proteins domains can function even with big parts missing.
2015
science
CORBEL: bridging research infrastructures
Lab Matters Major EU funding for CORBEL, facilitating access to data and biological imaging facilities.
2015
lab-matters
New Joint Directors of EMBL-EBI
Lab Matters Rolf Apweiler and Ewan Birney appointed Joint Directors of EMBL-EBI, as Janet Thornton steps down.
2015
lab-matters
Bioinformatics services: Winter 2015
Lab Matters A quick round-up of the latest EMBL-EBI service releases.
2015
lab-matters
Supporting women in science
Lab Matters Wellcome Genome Campus gives first Best Practice Award for Supporting Women in Science.
2015
lab-matters
Jeffrey Barrett to lead CTTV
Lab Matters Jeffrey Barrett appointed Director of CTTV, the GSK, EMBL-EBI and Sanger Institute partnership.
2015
lab-matters
Why is a dolphin not a cat?
Science How repurposing non-coding elements in the genome gave rise to the great ‘mammalian radiation’.
2015
science
Beyond COMPARE
Lab Matters New project aims to speed up detection and response to disease outbreaks using genome technology.
2015
lab-matters
Relaunching YourGenome.org
Lab Matters EMBL-EBI supports relaunch of yourgenome.org, to bring genetics advances to a wider audience.
2015
lab-matters
‘Hairclip’ protein mechanism explained
Science Research led by Teichmann group identifies fundamental mechanism for controlling protein function.
2015
science
What makes a mosquito deadly?
Science Genome-based insights into evolution of malaria-carrying Anopheles mosquitoes.
2014
science
Record parasitic worm dataset
Science Largest collection of helminth genomic data ever assembled, in new open-access WormBase ParaSite.
2014
science
Argentina: EMBL in action
Lab Matters Workshops, seminars and honorary lectures – strong start for EMBL’s newest associate member state.
2014
lab-matters
Big biology, big success
Events EMBL-EBI supports Big Biology Day, inspiring 500 youngsters with jelly-baby DNA and golf-tee viruses.
2014
events
Big (Protein) Data to Knowledge
Lab Matters 'Big Data to Knowledge' project by UCLA, Scripps and EMBL-EBI to transform protein data to knowledge.
2014
lab-matters
Building an EMPIAR
Science EMPIAR lets researchers take a closer look at the images used to build 3D molecular structures.
2014
science
Same pieces, different picture
Science Unprecedented detail on HIV structure continues virus’ string of surprises.
2014
science
Computational modelling resource
Science New, open repository helps researchers share computational models of disease.
2014
science
Kidney cancer in Central Europe
Science Kidney cancer linked to exposure to aristolochic acid, an ingredient in some herbal remedies.
2014
science
European Variation Archive launches
Science European Variation Archive makes it easier to explore detailed information about genetic variation.
2014
science
Job dispatched
Lab Matters How does EMBL-EBI run millions of jobs for its users while moving its two large data centres?
2014
lab-matters
Music of the spheres
Lab Matters Music, bubbles and DNA: a collaborative project brings artist and scientist together
2014
lab-matters
Awards & Honours
Lab Matters EMBL scientists regularly receive prestigious awards - meet the latest honourees
2014
lab-matters
EU Codefest
Events Pooling programming and problem-solving expertise in bioinformatics at EMBL-EBI.
2014
events
Genotype to phenotype mapping course
Events EMBL-EBI hosts successful first EMBO Practical Course in Genotype to Phenotype Mapping.
2014
events
Major advance in stem cell technology
Science Researchers produce pristine stem cells, which can be precisely changed into clinically relevant cell types.
2014
science
Gibbon genome joins Ensembl
Science Gibbon genome gives insights into evolution of this singing, swinging, tree-dwelling ape.
2014
science
RNAcentral Station
Science RNAcentral is the first unified resource for all types of non-coding RNA data.
2014
science
How do animals become domesticated?
Science Bronwen Aken discusses what research into the rabbit genome reveals about animal domestication.
2014
science
Art inspired by data science
Lab Matters Artist Stephen Wright gifts artwork inspired by DNA storage research to EMBL-EBI.
2014
lab-matters
Bioinformatics services: Summer 2014
Lab Matters A quick round-up of the latest EMBL-EBI service releases
2014
lab-matters
New EMBL-EBI data centre contract
Lab Matters Gyron Ltd awarded contract to supply EMBL-EBI's data centres over the next five years
2014
lab-matters
New, improved human genome
Science Ensembl has incorporated a vast amount of knowledge into a fully annotated reference human genome
2014
science
Celebrating 40 years of leading life science
Alumni "Thank you, EMBL, for changing my life" – reunion celebrates great science and great scientists
2014
alumni
New genomics API
Lab Matters New genomics API allows researchers to share anonymised genetic data seamlessly across platforms.
2014
lab-matters
Shedding light on chimeral twins
Science Marmoset genome provides insights into chimerism: data available in Ensembl genome explorer
2014
science
Celebrating 20 years of bioinformatics
Alumni EMBL-EBI’s anniversary celebration: blue skies thinking, Robin Ince and a biology-themed cake
2014
alumni
Forty things that make EMBL – Part 1
Lab Matters As the Lab turns 40, staff and alumni share 40 things that make EMBL, EMBL
2014
lab-matters
Branches: The search for our neighbours
Lab Matters What might life alien life look like? Lewis Dartnell studies extreme bacteria to find out
2014
lab-matters
Forty things that make EMBL – Part 2
Lab Matters As the Lab turns 40, staff and alumni share 40 things that make EMBL, EMBL
2014
lab-matters
The shape of things to come
Science New ways of handling and distributing data at PDBe to tackle ever larger and more complex proteins
2014
science
Q&A
Lab Matters Which scientific breakthroughs would EMBL scientists most like to see in the next 40 years?
2014
lab-matters
Five for the future
Lab Matters Scientists from EMBL's five sites reflect on the opportunities and challenges that might lie ahead
2014
lab-matters
On target
Lab Matters A new EMBL-EBI biomedical initiative works to determine the best target proteins for new drugs.
2014
lab-matters
Capturing marine biodiversity
Science Data from first ever worldwide Ocean Sampling Day will be shared via EMBL-EBI resources this autumn.
2014
science
Cross-Channel collaboration
Events Teaming up in Ireland to address big challenges in biology
2014
events
Sheep genome provides rich resource for agricultural research
Science Reference sheep genome, published by International Sheep Genomics Consortium, available in Ensembl
2014
science
Insights into genetics of cleft lip
Science How a DNA stretch influences face formation and contributes to common congenital malformations
2014
science
How immune cells use steroids
Science Genome Campus researchers discover that some immune cells turn themselves off by producing a steroid.
2014
science
Tsetse fly genome sequenced
Science Tsetse fly genome sequenced; scientists hope to find new ways to control sleeping sickness.
2014
science
Evolution by ‘copy-paste’
Science A team of geneticists and computational biologists at the European Molecular Biology Laboratory’s European Bioinformatics Institute (EMBL-EBI), the Wellcome Trust Sanger Institute and Cancer Research UK reveal how an ancient mechanism is involved in gene control and continues to drive genome…
2012
science
Five countries and EMBL sign Memorandum of Understanding to make ELIXIR a reality
Lab Matters Today marks an important step for ELIXIR, Europe’s emerging research infrastructure for life-science information, as five countries plus the European Molecular Biology Laboratory (EMBL) have signed a Memorandum of Understanding to catalyse the implementation and construction of ELIXIR. The…
2011
lab-matters
BBSRC and EMBL-EBI welcome UK funds earmarked for major bioscience data infrastructure project
Lab Matters The Biotechnology and Biological Sciences Research Council (BBSRC) and the European Molecular Biology Laboratory’s European Bioinformatics Institute (EMBL-EBI) welcome news that funding has been earmarked from the UK’s Large Facilities Capital Fund for ELIXIR – the European Life-science…
2011
lab-matters
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