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Structural Biology

Crystal selection for X-ray diffraction experiments.

Investigating the structure and mechanisms of coronavirus biomolecules

While global research on coronaviruses has shed light on the function of many SARS-CoV-2 proteins, the role of some crucial components remains unknown. Researchers at EMBL Grenoble will use a range of structural biology methods to try to solve some of the puzzles of the molecular mechanics of…

By Adam Gristwood

Science

This image shows the structure of a bacterial group II intron

Genetic cut and paste at atomic resolution

Researchers in the Marcia group at EMBL Grenoble and the De Vivo lab at the Italian Institute of Technology in Genoa have obtained some of the most detailed ever snapshots of the splicing process in systems known as group II self-splicing introns. The new insights will help scientists to develop…

By Marius Bruer

Science

Automated sample changer and diffractometer at the ID30B X-ray crystallography beamline at ESRF Grenoble.

Facilitating COVID-19 structural biology research

EMBL and the European Synchrotron Radiation Facility (ESRF) restart the activities of the Joint Structural Biology Group in Grenoble to support coronavirus-related projects. A new initiative will allow users to be granted access to the High-Throughput Crystallisation (HTX) lab at EMBL and to a…

By Marius Bruer

Science

EMBL SPC facility supports COVID-19 projects

The Sample Preparation and Characterisation Facility (SPC) at EMBL Hamburg reopens to support scientists working on Covid-19 research. The SPC Facility is one of the best equipped facilities in Europe is therefore in high demand from external users. Re-opening the facility also allows experts at…

By Sara Verstraeten

Science

Liquid handling robot transfering protein crystalisation solutions

Responding to health threats posed by coronaviruses

By re-opening the High-Throughput Crystallisation (HTX) lab at EMBL Grenoble, EMBL is supporting structural biology projects to respond to the health threats posed by coronaviruses.…

By Sara Verstraeten

Science

Crystallization reagents being prepared by a pipetting robot at the HTX lab.

Remote access to EMBL structural biology pipelines to support research on SARS-CoV-2

The Marquez Team has restarted operations at the High-Throughput Crystallisation (HTX) lab at EMBL Grenoble. The team has developed a fully automated protein-to-structure pipeline, which can be operated remotely and provides virtual access to the facilities.…

By Sara Verstraeten

Science

Supporting international research on the structure of the coronavirus

EMBL Heidelberg reopens the Cryo-Electron Microscopy Service Platform to support coronavirus structural biology research.…

By Anne-Marie Alleaume

Science

3D reconstruction of parental chromosomes in the mouse embryo

How chromosome structure influences development

EMBL researchers in the Heard group at EMBL Heidelberg explore the interaction between DNA organisation and gene expression in the early embryo…

By Fabian Oswald

Science

Meytal Landau with Thomas Dobner, Katharina Fegebank and Matthias Wilmanns

Meytal Landau: a visiting researcher in Hamburg

Strengthening ties between EMBL and Israel through the Scientific Visitor Programme…

By Cella Carr

Science

Before a biological sample reaches the beamline, a lot of work is put into its preparation. Scientists can use the wide range of services and resources at EMBL to prepare their biological samples for structural studies at the X-ray beamlines in Grenoble and Hamburg. Photo: Marietta Schupp/EMBL

Empowering European structural biology

EU funding for iNEXT-Discovery consortium unlocks key technologies for structural biology…

By Iris Kruijen

Lab Matters

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