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bioinformatics

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8 March 2024 MGnify logo with text underneath which reads release

MGnify Genomes mouse gut catalogue v1.0 released

Updates from data resources The MGnify data resource for microbiome data has launched the latest MGnify Genomes catalogue comprising 112,951 genomes derived from mouse gut datasets, represented by 2,847 species-level cluster representative genomes. This catalogue was generated as part of our work with the MRC funded…

2024

updates-from-data-resources

28 February 2024 DECIPHER logo

DECIPHER v11.24 Released

Updates from data resources Version 11.24 of DECIPHER introduces a new ACMG/AMP pathogenicity interface for sequence variant predictions, displays ClinGen Variant Curation Expert Panel recommendations on gene pages, and updates ACMG secondary finding information to v3.2.

2024

updates-from-data-resources

29 January 2024 InterPro logo

InterPro 98.0 released

Updates from data resources InterPro version 98.0 and InterProScan 5.66-98.0 are now available. InterPro now features hundreds of new methods integrated from partner databases, and InterProScan draws on over 40000 entries. InterPro version 98.0 New features include: InterPro 98.0 covers 81.7% of UniProt Knowledgebase release…

2024

updates-from-data-resources

14 November 2023 InterPro logo

InterPro 97.0 released

Updates from data resources InterPro version 97.0 and InterProScan 5.64-97.0 are now available. InterPro now features hundreds of new methods integrated from partner databases, and InterProScan draws on over 40000 entries.

2023

updates-from-data-resources

7 July 2023 InterPro logo

InterPro 95.0 released

Updates from data resources InterPro version 95.0 and InterProScan 5.63-95.0 are now available! InterPro now features hundreds of new methods integrated from partner databases, and InterProScan draws on over 39000 entries. InterPro version 95.0 – new features include: InterPro 95.0 covers 81.7% of UniProt Knowledgebase…

2023

updates-from-data-resources

3 July 2023 In the foreground: an intrinsically disordered protein, which has a form of a tangled, unstructured string. In the background: a set of parallel curved lines.

Bringing research on disordered proteins to order

Science, Science & Technology A third of all known proteins are either completely or partially unstructured. EMBL scientists contributed to a new set of guidelines – Minimum Information About a Disorder Experiment (MIADE) – that will help researchers share data on unstructured proteins in a more useful way and will enable…

2023

sciencescience-technology

29 March 2023 Photographs of two male scientists in circular insets against a decorative background

EMBL Alumni Awards Announced for 2023

Alumni Two former EMBL scientists have been recognised for their outstanding contributions to the fields of science communication and multiple sequence alignment research, respectively.

2023

alumni

7 March 2023 InterPro logo

New releases: InterPro 93.0 and InterProScan 5.61-93.0

Updates from data resources InterPro now features hundreds of new methods integrated from partner databases, and InterProScan draws on over 38,000 entries. InterPro version 93.0 InterPro 93.0 integrates 300 new methods from the CDD (261), PANTHER (12), PROSITE profiles (17), SMART (9), TIGRFAMs (1) databases, and covers 81.7%…

2023

updates-from-data-resources

23 February 2023 Decorative image

New Job Dispatcher website launched

Updates from data resources EMBL-EBI’s Software Development and Operations team is delighted to announce the launch of a brand-new Job Dispatcher website, currently in development.  The updated website provides a landing page for the Job Dispatcher services, making it easier for users to find and navigate services…

2023

updates-from-data-resources

20 December 2022

First linked dataset on Pathogens Portal

Updates from data resources The first  cohort study linking data across categories was recently added on the Pathogens Portal Cohort Browser and is also accessible from the BioSamples browser. This pilot study comes from Erasmus Medical Centre through the ReCoDID project, one of the COVID-19 Data Platform supporting…

2022

updates-from-data-resources

21 October 2022 Ensembl logo in white circle on blue and green background

Ensembl 108 has been released

Updates from data resources We are pleased to announce the release of Ensembl 108, and the corresponding release of Ensembl Genomes 55 featuring changes in the human default tracks, new genomes in Ensembl Plants and Ensembl Metazoa, and the addition of mitochondrial annotation for Tasmanian devil. Genome assemblies and…

2022

updates-from-data-resources

18 July 2022 Large, elongated purple molecule has an on/off switch on it pointed to on.

The retron switch

Science, Science & Technology EMBL researchers now understand the function of an elusive small DNA in bacteria and have developed a tool that can be used to better understand what might ‘switch on’ bacterial immune defences.

2022

sciencescience-technology

24 February 2022 Expression Atlas database logo - A magnifying glass highlighting a yellow section on a blue background

New Expression Atlas release in collaboration with PRIDE

Updates from data resources New Expression Atlas release features differential-proteomics and baseline-proteomics experiments in collaboration with the PRIDE team at EMBL-EBI. This also includes new baseline DIA proteomics experiments as well as new differential proteomics datasets.  To improve reproducibility,…

2022

updates-from-data-resources

21 May 2021 Image of a mosquito on a clear surface

EMBL scientists support malaria research

Science, Science & Technology EMBL scientists support research on malaria by providing freely available data resources and using innovative experimental approaches. Our Course and Conference Office facilitates the exchange of knowledge in the field by hosting the annual BioMalPar conference.

2021

sciencescience-technology

15 October 2020 Four blue circular objects are surrounded with green structures, and the central blue circle with pink structures. The blue circles are human cell nuclei, and pink and green structures are proteins.

Repurposing drugs for a pan-coronavirus treatment

Science, Science & Technology Scientists from the Beltrao Group at EMBL-EBI and collaborators identified drug targets common to SARS-CoV-2, SARS-CoV-1, and MERS-CoV, three pathogenic coronaviruses. They also found potential drugs that could be repurposed as COVID-19 treatments, and against emerging coronavirus strains in the…

2020

sciencescience-technology

10 September 2020 Two researchers at EMBL's state-of-the-art Electron Microscopy Core Facility (EMCF). A female scientist is using a binocular microscope, a male scientist is standing next to her.

Level up!

Lab Matters ARISE fellowships to offer first-ever comprehensive training for bioscience infrastructure operations

2020

lab-matters

3 August 2020 A woman with glasses holds a book. The book cover says "Gene naming rules". Thought bubbles float around her head and display gene symbols like BRCA1.

Bagpipe and Pokemon, or how not to name a human gene

Science, Science & Technology The human genome harbours about 19 000 protein-coding genes, many of which still have no known function. As scientists unveil the secrets of our DNA, they come across novel genes that they need to refer to using a unique name. The Human Genome Organisation’s Gene Nomenclature Committee (HGNC) at…

2020

sciencescience-technology

20 July 2020 A magnifying glass hovers over the human gut, revealing its biodiversity.

Unparalleled inventory of the human gut ecosystem

Science, Science & Technology An international team of scientists has collated all known bacterial genomes from the human gut microbiome into a single large database. Their work will allow researchers to explore the links between bacterial genes and proteins, and their effects on human health.

2020

sciencescience-technology

5 February 2020

Analysis of human genomes in the cloud

Science, Science & Technology Scientists from EMBL present a tool for large-scale analysis of genomic data with cloud computing. Main advantages of the new tool, called Butler, are continuous system monitoring and its ability to self-heal in case of failure, allowing for 43% more efficient data processing than previous…

2020

sciencescience-technology

4 August 2016 45 pupils from Saarland, Germany visit EMBL-EBI

Just try!

Lab Matters German students visit EMBL-EBI on a tour to explore a new culture and different career paths

2016

lab-matters

2 December 2015 Gut bacteria are more affected by metformin than by the type-2 diabetes it is prescribed to treat. IMAGE: Courtesy of Pacific Northwest National Laboratory (BY-NC-SA)

Drugging bacteria

Science Commonly used diabetes drug metformin impacts gut bacteria more than disease itself

2015

science

2 October 2015 The 1000 Genomes Project: a timeline

A lasting legacy

Science 1000 Genomes Project pushed technologies and knowledge forward to understand what is 'normal' human genetic variation

2015

science

28 September 2015

EMBL-EBI training news

Events Highlights from EMBL-EBI’s Training Programme: Open Day, revamped webpages, free webinar series.

2015

events

24 August 2015 Janet Thornton. Photo: Robert Slowley

Transitions

Lab Matters Janet Thornton reflects on her time as Director of one of Europe’s fastest growing research institutes.

2015

lab-matters

27 May 2015

ELIXIR accelerates

Lab Matters ELIXIR receives major Horizon 2020 funding to ‘EXCELERATE' activities over the next four years.

2015

lab-matters

20 January 2015 COMPARE project

Beyond COMPARE

Lab Matters New project aims to speed up detection and response to disease outbreaks using genome technology.

2015

lab-matters

17 November 2014 Judith Zaugg. PHOTO: EMBL/M. SCHUPP

Welcome: Judith Zaugg

Science Whether it’s information or people, the art of connecting is key to new group leader Judith Zaugg

2014

science

21 October 2014 Map of EMBL-EBI users

Job dispatched

Lab Matters How does EMBL-EBI run millions of jobs for its users while moving its two large data centres?

2014

lab-matters

8 October 2014

EU Codefest

Events Pooling programming and problem-solving expertise in bioinformatics at EMBL-EBI.

2014

events

10 September 2014 RNAcentral launched

RNAcentral Station

Science RNAcentral is the first unified resource for all types of non-coding RNA data.

2014

science

1 July 2014 Vasily Sysoev

Back to school

Lab Matters School ambassadors show next generation that scientists are more ‘role model’ than ‘mad professor’

2014

lab-matters

4 March 2010

Bacterial balance that keeps us healthy

Science The thousands of bacteria, fungi and other microbes that live in our gut are essential contributors to our good health. They break down toxins, manufacture some vitamins and essential amino acids, and form a barrier against invaders. A study published today in Nature shows that, at 3.3 million,…

2010

science

19 January 2010 Image credit: Rachel Melwig & Christine Panagiotidis / EMBL

Membrane-coat proteins: bacteria have them too

Science Although they are present almost everywhere, on land and sea, a group of related bacteria in the superphylum Planctomycetes-Verrucomicrobia-Chlamydiae, or PVC, have remained in relative obscurity ever since they were first described about a decade ago. Scientists at the European Molecular Biology…

2010

science

18 January 2010

Open access drug discovery database launches with half a million compounds

Science ChEMBLdb, a vast online database of information on the properties and activities of drugs and drug-like small molecules and their targets, launches today with information on over half a million compounds. The data lie at the heart of translating information from the human genome into successful new…

2010

science

22 January 2008

International consortium announces the 1000 Genomes Project

Lab Matters Drawing on the expertise of multi-disciplinary research teams, the map developed by the 1000 Genomes Project will provide a view of biomedically relevant DNA variations at a resolution unmatched by current resources. The European Bioinformatics Institute (EBI), working with long-term collaborator…

2008

lab-matters

23 October 2007

The East Wing and a new dawn for the EMBL-EBI

Lab Matters The European Molecular Biology Laboratory’s European Bioinformatics Institute (EMBL-EBI) officially opens its new East Wing today with a reception for prominent guests. The East Wing will be jointly opened by Ian Pearson, Minister of State for Science and Innovation, UK, and Robert-Jan Smits,…

2007

lab-matters

27 November 2006

CiteXplore

Lab Matters Today the European Molecular Biology Laboratory’s European Bioinformatics Institute (EMBL-EBI) launches CiteXplore, a new freely accessible literature resource service. Biological researchers require two crucial sources of information: scientific literature published in peerreviewed…

2006

lab-matters

28 February 2005

Double recognition of EBI scientists by the ISCB

Lab Matters The International Society for Computational Biology has named two scientists from the European Bioinformatics Institute as the winners of its awards for 2005. Janet Thornton wins the Senior Scientist Accomplishment Award while the Overton Prize goes to Ewan Birney. Thomas Lengauer, the ISCB’s…

2005

lab-matters

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