Welcome: Christina Ernst
People & Perspectives EMBL-EBI's new Functional Genomics Team Leader will develop standards for new data types and integrate AI into workflows.
2024
people-perspectivesperspectives
Read the latest Issue
Sparking a data revolution
Science & Technology The introduction of computational methods in biology opened up an entirely new world of insights and breakthroughs. Over the last several decades, EMBL has been at the forefront of discoveries and innovations that have not only propelled the field forward but also opened up access to bioinformatics…
2024
science-technology
Human immune system is ‘ready to go’ long before birth
The most comprehensive map of the developing human thymus sheds light on how immune responses are built and maintained during early life
2024
announcements
Welcome: Dan Trigg
Tell us a little bit about yourself. I’m a chartered civil engineer and I’ve worked in different capacities in the building and construction space. I worked for a contractor, delivering large infrastructure projects, such as roads, tunnels, bridges all over the UK. I also worked as a…
2024
perspectives
DECIPHER v11.28 Released
The v11.28 DECIPHER release is out now. Find out about the new features and improvements.
2024
updates-from-data-resources
BioChemGraph: Unifying structural and bioactivity data to accelerate drug discovery
In the era of data-driven biology, integrating information from different resources is essential yet often challenging. The BioChemGraph project addresses this challenge by creating infrastructure that consolidates structural, functional, and biochemical annotations for small molecules and their…
2024
updates-from-data-resources
InterPro 102.0 released
InterPro version 102.0 and InterProScan 5.70-102.0 are now available.
2024
updates-from-data-resources
Ensembl 113 and Ensembl Genomes 60 have been released
Ensembl 113 brings major gene and regulatory feature annotation updates in Homo sapiens (human) and Mus musculus (mouse).
2024
updates-from-data-resources
Cancer drug resistance causes and categories identified
Researchers uncover that DNA changes that cause cancer drug resistance can be grouped into four categories, and identify possible new therapeutic targets.
2024
announcements
Computational protein design and protein structure prediction win Nobel Prize in Chemistry
Science & Technology Creators of AI system AlphaFold receive 2024 Nobel Prize for Chemistry.
2024
sciencescience-technology
New MGnify Proteins web resources launched
EMBL-EBI’s microbiome data resource MGnify produces a valuable trove of protein sequence data through its ongoing analysis of microbiome derived data. Two new MGnify Proteins web resources make this dataset easily accessible and searchable, both for large queries across the entire database…
2024
updates-from-data-resources
Funding awarded to develop a global Pathogen Data Network
EMBL-EBI and colleagues from other 11 institutes commit to pathogen data sharing project.
2024
announcements
Polygenic Score (PGS) Catalog increases diversity and usability of genetic data
Science & Technology Addition of data from more diverse populations to the Polygenic Score (PGS) Catalog and a new software tool for PGS calculation could help produce more equitable disease risk predictions.
2024
science-technologytechnology-and-innovation
Single Cell Expression Atlas 21 released
New datasets The release has 381 single-cell RNA-Seq experiments, consisting of more than 13.5 million cells from 21 different species to explore in the Single Cell Expression Atlas (SCEA). The resource now includes an entirely new class of data – externally analysed data, marked with an…
2024
updates-from-data-resources
We are EMBL: Iguaracy Pinheiro-de-Sousa on organoids and nanorobot ‘highways’
People & Perspectives EMBL-EBI Postdoctoral researcher Iguaracy Pinheiro de Sousa is using bioinformatics to support the development of better organoids.
2024
people-perspectivesperspectives
EMBL-EBI’s open data resources for biodiversity and climate research
Science & Technology EMBL-EBI data resources help advance biodiversity and climate change research by enabling scientists to study species interactions, evolutionary processes, ecosystem health, and more.
2024
science-technologytechnology-and-innovation
AlphaFold database empowers researchers with enhanced structural search via Foldseek integration
Traditional sequence search methods are fast and efficient but rely solely on comparing amino acid sequences. This approach can miss crucial insights because proteins with similar functions can have vastly different sequences. Although their sequences have diverged, these proteins often retain 3D…
2024
updates-from-data-resources
Alvis Brazma: What I’ve learned
People & Perspectives EMBL-EBI alumnus Alvis Brazma reflects on how mathematics and mountaineering have shaped his life and why keeping things simple in bioinformatics is key.
2024
people-perspectivesperspectives
Welcome: David Ocaña
People & Perspectives EMBL-EBI’s new Head of Applications will use his expertise in cloud infrastructure and security to support the institute’s open data resources.
2024
people-perspectivesperspectives
Why clinical trials stop: the role of genetics
Science & Technology Using machine learning to analyse the genetic factors behind early clinical trial termination, researchers find a link between genetic evidence and trial outcome.
2024
research-highlightsscience-technology
DECIPHER v11.27 release
The v11.27 DECIPHER release is out now. Find out about the new features and improvements.
2024
updates-from-data-resources
We are EMBL: Melanie Schneider on changing career trajectory
People & Perspectives ARISE fellow Melanie Schneider shares how she uncovered a new interest in research infrastructures and supporting discovery.
2024
people-perspectivesperspectives
We are EMBL: Kim Gurwitz on working with global partners to support bioinformatics training
People & Perspectives Kim Gurwitz talks about her role as Scientific Training Lead at EMBL-EBI and how collaborative projects for bioinformatics training support researchers and service providers in making the most of publicly available data.
2024
people-perspectivesperspectives
Proteomics: a different lens for precision medicine
Science & Technology The dynamic world of proteomics is shaping the future of personalised medicine, but some obstacles stand in the way
2024
perspectivesscience-technology
The EMBL evolution: Ewan Birney on open data and the ethos of excellence
People & Perspectives Ewan Birney reflects on his time at EMBL and the development of the organisation through a commitment to open data and nurturing scientific talent.
2024
people-perspectivesperspectives
Welcome: Mallory Freeberg
People & Perspectives The new Team Leader for Human Genomics at EMBL-EBI shares how curiosity and maths shaped her career and what it takes to be a community builder.
2024
people-perspectivesperspectives
Ancient environmental DNA provides solutions for global food security challenges
EMBL Announcements Researchers explore genetic diversity found in ancient environmental DNA to help modern agricultural practices.
2024
announcementsembl-announcements
IntAct reaches 1.5 million binary interaction evidences
IntAct 247 release is now public with over 1.5 million binary interaction evidences
2024
updates-from-data-resources
Case study: Discovering new enzymes to upcycle food waste
Science & Technology EMBL-EBI data resource helps scientists upcycle animal by-products.
2024
perspectivesscience-technology
The EMBL-EBI File Replication Archive hits 100 petabytes
A behind-the-scenes look at EMBL-EBI's in-house archive that supports major open data resources and ingests record amounts of data
2024
technology-and-innovation
DECIPHER v11.26 release
The latest DECIPHER release includes AlphaMissense scores, links to the Open Targets Platform and more.
2024
updates-from-data-resources
Predicting cancer risk on the basis of national health data
Science & Technology Large-scale study uses data from Danish health registries to predict individual risks of developing cancer
2024
research-highlightsscience-technology
AlphaMissense data integrated into Ensembl, UniProt, DECIPHER and AlphaFold DB
The integration enables researchers to easily access AI-generated scores estimating how likely genetic variants are to be pathogenic
2024
technology-and-innovation
Calling data resource users: we need your feedback
EMBL-EBI asks users to fill in a services survey to help shape the future of the open data resources managed by the institute
2024
announcements
Expression Atlas 40 released
The latest Expression Atlas 40 release is now live, containing new RNA-seq datasets, including a featured experiment resulting from a collaboration with Genotype Tissue Expression (GTEx) project as well as new proteomics data derived from our collaboration with PRIDE. In total, this release…
2024
updates-from-data-resources
Welcome: Julio Saez-Rodriguez
People & Perspectives EMBL-EBI's new Head of Research shares his plans and priorities.
2024
people-perspectivesperspectives
Ensembl 112 has been released
Ensembl 112 and the corresponding release of Ensembl Genomes 59 has released. This includes exciting new fish species, many more drosophila species and new VEP updates.
2024
updates-from-data-resources
We are EMBL: María Cerezo on balancing two roles and one of EMBL’s proudest achievements
People & Perspectives María Cerezo talks about her role as Scientific Curator, how she combines it with her position as co-chair of the Staff Association, and what she believes has been EMBL's biggest achievement in its first 50 years.
2024
people-perspectivesperspectives
Changes to EMBL-EBI’s Senior Management Team
EMBL-EBI's Senior Management Team announces new appointment and title changes.
2024
announcements
MSD joins the Open Targets consortium
EMBL Announcements MSD joins as the latest partner in the Open Targets consortium, enhancing the initiative’s collaborative efforts in drug discovery.
2024
announcementsembl-announcements
Researchers aim to use quantum computing to assemble and analyse pangenomes
Science & Technology Experts in quantum computing and genomics to develop new methods and algorithms to process biological data.
2024
announcementsscience-technology
Exploring cellular complexity with EMPIAR’s new cryo-electron tomography prototype browser
EMBL Announcements Data obtained through cryogenic sample electron tomography (cryo-ET) are openly available in the new Electron Microscopy Public Image Archive (EMPIAR) cryo-ET tomography browser.
2024
announcementsembl-announcements
When AI meets biology
Science & Technology A recent EMBO | EMBL conference provided a forum for researchers to share how AI is making a difference in biology and bioinformatics.
2024
science-technology
DECIPHER v11.25 released
The latest DECIPHER update, version 11.25, introduces new key features including the integration of functional data from multiplexed assays of variant effect (MAVEs) and much more.
2024
updates-from-data-resources
‘Exhausted’ immune cells in healthy women could be target for breast cancer prevention
Science & Technology New study uncovers the potential of immunotherapy in preventing breast cancer and creates the openly available Human Breast Cell Atlas.
2024
research-highlightssciencescience-technology
Using Data Hubs to analyse SARS-CoV-2 and other pathogen sequences
The SARS-CoV-2 Data Hubs are a set of tools coupled with infrastructure that support four components: the submission, analysis, presentation and visualisation of SARS-CoV-2 raw read data, and its resulting analyses. What makes Data Hubs attractive is a unique set of features: A new publication in…
2024
updates-from-data-resources
Sense makers: how standards are enabling data reuse
People & Perspectives Data standards that have been silently enabling discovery in the life sciences for decades are now making AI advances possible.
2024
people-perspectivesperspectivesscience
AI annotations increase patent data in SureCheMBL
AI annotations added to the SureChEMBL database increase the depth of data made available to users.
2024
sciencetechnology-and-innovation
The AI revolution hinges on accessible training
People & Perspectives Team Leader Sameer Velankar on why accessible training is key for AlphaFold and AI tools more generally.
2024
people-perspectivesperspectivesscience
MGnify Genomes mouse gut catalogue v1.0 released
The MGnify data resource for microbiome data has launched the latest MGnify Genomes catalogue comprising 112,951 genomes derived from mouse gut datasets, represented by 2,847 species-level cluster representative genomes. This catalogue was generated as part of our work with the MRC funded…
2024
updates-from-data-resources
The malaria parasite generates genetic diversity using an evolutionary ‘copy-paste’ tactic
Science & Technology Plasmodium falciparum, a malaria parasite, uses gene conversion to produce genetic diversity in two surface protein genes targeted by the human immune system.
2024
announcementssciencescience-technology
Team SAMBAI: addressing cancer disparities in recent African heritage populations
Science & Technology An international team of researchers aim to combine social determinants of health with genomics, immune profiling, and exposomics data to tackle cancer inequities at an unprecedented scale.
2024
announcementssciencescience-technology
First datasets available in the Federated EGA Network
The Federated European Genome-phenome Archive (FEGA) marks a significant milestone with the release of its first datasets.
2024
announcements
DECIPHER v11.24 Released
Version 11.24 of DECIPHER introduces a new ACMG/AMP pathogenicity interface for sequence variant predictions, displays ClinGen Variant Curation Expert Panel recommendations on gene pages, and updates ACMG secondary finding information to v3.2.
2024
updates-from-data-resources
We are EMBL: Jacqueline Toussaint on strange bacteria and bioinformatics
Lab MattersPeople & Perspectives Jacqueline shares her experience of EMBL's international PhD programme.
2024
lab-matterspeople-perspectives
Europe PMC supports preprint peer review
New Europe PMC tools support preprint review discovery
2024
updates-from-data-resources
We are EMBL: Renato Alves on Bio-IT and stargazing
Lab MattersPeople & Perspectives Renato Alves talks about his time at EMBL, the Bio-IT project, his wishes for EMBL in its anniversary year, and how a passion for night hikes and stargazing led to the creation of EMBL’s astronomy club.
2024
lab-matterspeople-perspectives
InterPro 98.0 released
InterPro version 98.0 and InterProScan 5.66-98.0 are now available. InterPro now features hundreds of new methods integrated from partner databases, and InterProScan draws on over 40000 entries. InterPro version 98.0 New features include: InterPro 98.0 covers 81.7% of UniProt Knowledgebase release…
2024
updates-from-data-resources
Welcome: Kyle Morris
Lab MattersPeople & Perspectives Kyle Morris joins EMBL-EBI as Electron Microscopy Data Bank (EMDB) Team Leader.
2024
lab-matterspeople-perspectives
ProteomicsML: empowering proteomics research with machine learning
Streamlining proteomics data access for machine learning applications.
2024
sciencetechnology-and-innovation
Ensembl 111 has been released
The Ensembl 111 features a range of new Ensembl VEP plugins and updated agricultural, fish, plant and metazoa species.
2024
updates-from-data-resources
The Biodiversity Cell Atlas: charting cellular diversity on Earth
A $3.8 million grant from the Gordon and Betty Moore Foundation will help researchers lay groundwork for the Biodiversity Cell Atlas.
2024
announcements
Unravelling the role of immune cells in early lung development
Science & Technology Researchers reveal that healthy lung development hinges on immune-epithelial crosstalk, with implications for respiratory diseases.
2023
research-highlightsscience-technology
UKRI funding supports EMBL-EBI infrastructure upgrade in response to increasing data demand
UK Research and Innovation (UKRI) has confirmed £80.7 million of funding for EMBL’s European Bioinformatics Institute (EMBL-EBI). The funding comes from the UKRI Infrastructure Fund and will be distributed over the course of six years. It is set to help EMBL-EBI transform its technical…
2023
announcements
The Global Biodiversity Portal: enabling biodiversity research worldwide
Science & Technology The new initiative brings together genomic data from various biodiversity projects to aid conservation and biodiversity efforts.
2023
announcementssciencescience-technology
Extending the network of infectious disease data portals: developments in Sweden and The Netherlands
Two new data portals are set to support infectious disease monitoring and research across Europe; the Swedish Pathogens Data Portal and the Netherlands COVID-19 Data Portal.
2023
updates-from-data-resources
EMBL-EBI co-leads on research programme to help treat relapsed childhood cancers
Leading charities Children with Cancer UK and Cancer Research UK will co-fund a major £5.5 million research programme to advance precision medicine for relapsed childhood cancers.
2023
announcements
How AI shapes the life sciences: an interview with Oliver Stegle
Lab MattersPeople & Perspectives EMBL scientist Oliver Stegle explains how AI-based tools have the potential to transform our ability to better understand the complexity of life and how these tools will shape the future of life science exploration.
2023
lab-matterspeople-perspectives
Deciphering the data deluge: how large language models are transforming scientific data curation
Large language models are changing the way we carry out scientific data curation, annotation, and research, setting the stage for a more efficient understanding of scientific literature
2023
technology-and-innovation
Starting is easy, sustaining is hard
Where to start when thinking about the sustainability of informatics projects
2023
perspectives
Deciphering the data deluge: how large language models are transforming scientific data curation
EMBLetc Large language models are changing the way we carry out scientific data curation, annotation, and research, setting the stage for a more efficient understanding of scientific literature
2023
InterPro 97.0 released
InterPro version 97.0 and InterProScan 5.64-97.0 are now available. InterPro now features hundreds of new methods integrated from partner databases, and InterProScan draws on over 40000 entries.
2023
updates-from-data-resources
BioImage Archive democratises access to microscopy data
Users no longer need to download large datasets with the new galleries feature
2023
updates-from-data-resources
Reducing the carbon footprint of scientific computing
As science increasingly relies on big data and AI tools, the carbon footprint of computational work is on the rise
2023
perspectives
A leap in user experience: AlphaFold Database introduces sequence-based search and structure cluster members
In response to user community demands, the AlphaFold Protein Structure database has introduced sequence-based search and cluster members.
2023
updates-from-data-resources
ggCaller: The next step in scaling up bacterial genome annotation
The Lees group develops a tool that can scale up bacterial genome annotation.
2023
research-highlights
InterPro 96.0 released
InterPro version 96.0 and InterProScan 5.64-96.0 are now available.
2023
updates-from-data-resources
We are EMBL: Valentina Lorenzi on human reproductive development
Lab MattersPeople & Perspectives PhD student Valentina Lorenzi is using single-cell sequencing data to create a map of the developing human reproductive system.
2023
lab-matterspeople-perspectivesperspectives
Understanding the mechanisms of enzyme catalysis
Science & Technology Enzymes constitute a large fraction of genomes – 20% in humans – which makes them a very important part of life. Despite decades of studies and a rich literature dedicated to understanding the reaction mechanisms of enzymes, the rules of enzyme catalysis are still not fully clear. A new…
2023
science-technologytechnology-and-innovation
New predictions of genetic variant pathogenicity using AlphaFold protein structures
Science & Technology Ensembl Variant Effect Predictor integrates Google DeepMind’s new AlphaMissense Database for better predictions of genetic variant pathogenicity.
2023
science-technologytechnology-and-innovation
Uncovering the mechanisms underlying lack of response to immunotherapy
Science & Technology New research improves understanding of the molecular mechanisms behind why some cancers respond to immunotherapy and others don't.
2023
research-highlightssciencescience-technology
Revealing the secrets of protein evolution using the AlphaFold database
Science & Technology Researchers use the AlphaFold database and Foldseek Cluster algorithm to analyse millions of predicted protein structures and offer new insights into protein evolution.
2023
research-highlightssciencescience-technology
Nurturing computational excellence: the unique research culture at EMBL-EBI
EMBL-EBI’s Deputy Head of Research Virginie Uhlmann delves into the institute’s unique research landscape and the essential qualities for effective leadership in this field
2023
perspectives
From data management to AI: an interview with Laura Clarke
People & Perspectives Experience in data management and coordination has enabled EMBL alumna Laura Clarke to pursue a career in AI development.
2023
people-perspectivesperspectivesscience
Open data to power up the blue economy
People & Perspectives EMBL-EBI Senior Scientist Rob Finn explains why data coordination and sharing are fundamental for a sustainable blue economy.
2023
people-perspectivesperspectivesscience
Novel algorithm able to detect mutations in single-cell sequencing data sets
Science & Technology SComatic enables researchers to link genotype to phenotype using only single-cell profiling data
2023
research-highlightssciencescience-technology
Filling the skills gap to advance genomic medicine: an interview with Emily Perry
Lab MattersPeople & Perspectives By upskilling researchers on bioinformatics skills and tools, EMBL alumna Emily Perry is helping to make genomic medicine more accessible.
2023
lab-matterspeople-perspectivesperspectives
Ensembl Bacteria releases new annotation for all its genomes
Ensembl 110 and Ensembl Genomes 57 have introduced in-house prokaryotic gene annotation across genomes available in Ensembl Bacteria. Since its inception, Ensembl Bacteria has imported user-submitted annotations from the International Nucleotide Sequence Database Collaboration (INSDC) for…
2023
updates-from-data-resources
Latest release of the Expression Atlas
The latest Expression Atlas release is now live and contains a wider range of RNA-seq and proteomics datasets.
2023
updates-from-data-resources
refget v2.0 links the hidden dictionaries of DNA
The GA4GH standard refget quietly helps decipher millions of genomes sequenced worldwide, and it just got better.
2023
technology-and-innovation
Ensembl 110 has been released
Ensembl 100 release brings exciting updates, such as the addition of regulation data to 5 animal genomes studied extensively in agriculture.
2023
updates-from-data-resources
Latest release of IntAct and Complex Portal
We are excited to announce the latest releases of IntAct and Complex Portal. IntAct 244 highlights Complex Portal 244 highlights
2023
updates-from-data-resources
EMBL-EBI’s new building set to support data growth and innovative partnerships
EMBL AnnouncementsLab Matters Construction begins on EMBL-EBI's new building named after Janet Thornton.
2023
announcementsembl-announcementslab-matters
InterPro 95.0 released
InterPro version 95.0 and InterProScan 5.63-95.0 are now available! InterPro now features hundreds of new methods integrated from partner databases, and InterProScan draws on over 39000 entries. InterPro version 95.0 – new features include: InterPro 95.0 covers 81.7% of UniProt Knowledgebase…
2023
updates-from-data-resources
DECIPHER database for rare diseases joins EMBL-EBI
EMBL Announcements Closer collaborations with EMBL-EBI data resources set to further develop and grow this unique rare disease platform.
2023
announcementsembl-announcementsscience
Pathogens Portal: The new gateway to public pathogen data
Science & Technology Enabling researchers worldwide to share and analyse pathogen data generated across the world
2023
sciencescience-technologytechnology-and-innovation
David Hulcoop appointed as Open Targets Director
EMBL Announcements Coming from a pharmaceutical industry background, David Hulcoop is set to take over as Executive Director of the public-private partnership Open Targets.
2023
announcementsembl-announcements
Europe PMC ROR integration improves grant affiliations
Better search for Europe PMC funder grants with ROR IDs
2023
updates-from-data-resources
Bringing research on disordered proteins to order
Science & Technology A third of all known proteins are either completely or partially unstructured. EMBL scientists contributed to a new set of guidelines – Minimum Information About a Disorder Experiment (MIADE) – that will help researchers share data on unstructured proteins in a more useful way and will enable…
2023
sciencescience-technology
FAIRification framework: making your data Findable, Accessible, Interoperable, and Reusable
New framework to improve the FAIRness of clinical and molecular datasets
2023
perspectives
Supporting the development of hologenomic approaches for more sustainable animal feeds
Science & Technology HoloFood, the first consistent collection of multiomic data about chicken and salmon gut microbiomes, set to enable the development of better animal feeds.
2023
sciencescience-technologytechnology-and-innovation
Major user experience update in AlphaFold Database
The AlphaFold Database boasts improved user experience, including better search filters and an improved 3D viewer.
2023
updates-from-data-resources
Genomic medicine: ushering in a new era in healthcare
Science & Technology EMBL-EBI data resources are being used to deliver thousands of genetic diagnostics to patients every month.
2023
perspectivessciencescience-technology
Janet Thornton retires: a pioneer in structural bioinformatics
Lab MattersPeople & Perspectives In recognition of Janet Thornton’s retirement, we look back at some of her biggest accomplishments shaping the field of bioinformatics.
2023
announcementslab-matterspeople-perspectives
ProtVar: understanding missense variation in humans
Science & Technology A new tool for the interpretation of missense variation in humans – ProtVar – will help enable drug discovery.
2023
sciencescience-technologytechnology-and-innovation
Cancer cell ‘decathlon’ to help predict tumour aggressiveness and metastasis
Connections The PLAST-CELL project aims to understanding cancer progression by quantifying a cancer cell’s ability to respond to environmental stress that threatens its survival
2023
connectionstechnology-and-innovation
We are EMBL: Carolin Sauer on supporting cancer research
Lab MattersPeople & Perspectives Postdoctoral researcher Carolin Sauer is leveraging long-read sequencing to develop new detection methods for various cancers.
2023
lab-matterspeople-perspectivesresearch-highlights
New releases: InterPro 94.0 and InterProScan 5.62-94.0
InterPro 94.0 features hundreds of new methods integrated from partner databases, and InterProScan draws on over 38,000 entries.
2023
updates-from-data-resources
Managing a bioinformatics core facility
BioImage Archive Team Leader Matthew Hartley shares his experience and tips for people interested in managing a bioinformatics core facility.
2023
technology-and-innovation
Janet Thornton retires: a pioneer in structural bioinformatics
EMBLetc In recognition of Janet Thornton’s retirement, we look back at some of her biggest accomplishments in shaping the field of bioinformatics.
2023
The story of Clustal: democratising sequence alignments
EMBLetc Desmond Higgins, 2023 Lennart Philipson Award winner, discusses his time at EMBL and his research developing sequence alignment tools.
2023
What happens when chromosomes shatter
Science & Technology Understanding chromothripsis offers insights into how cancer develops.
2023
research-highlightsscience-technology
A more diverse human reference genome
Science & Technology The human pangenome – one of the most complete collections of genome sequences released so far – captures rich human diversity.
2023
announcementssciencescience-technology
Bioinformatics powers international effort to map gene function
Lab MattersScience & Technology EMBL-EBI is making a key contribution to a historic effort to understand the function of every human gene
2023
announcementslab-mattersscience-technology
The Human Genome Project at 20: interview with Ewan Birney
Lab MattersPeople & Perspectives On the 20th anniversary of the Human Genome Project, we look back at its history, wonder and potential.
2023
lab-matterspeople-perspectivesperspectives
EMBL alumni: Alex Almeida on the unchartered gut microbiome and becoming a principal investigator
People & Perspectives As a postdoc Alex Almeida used bioinformatics to push the boundaries of what we know about the gut microbiome. Here, Almeida explains how his time at EMBL-EBI generated new research avenues, and how the skills and connections from his postdoc prepared him for leading his own research group at the…
2023
people-perspectivesperspectives
WormBase ParaSite 18 released
Science & Technology WormBase ParaSite release 18 adds largest number of new genomes and annotations since launch, as well as full integration with AlphaFold.
2023
science-technologyupdates-from-data-resources
MAPLE: a phylogenetic tool for pandemic-scale genome data
Science & Technology EMBL-EBI researchers have developed a new tool capable of performing state-of-the-art phylogenetic inference on larger datasets than previously thought possible.
2023
research-highlightssciencescience-technology
Building a bioinformatics community at the nf-core hackathon
Connections Darwin Tree of Life project improves bioinformatics tools for biodiversity data analysis
2023
connectionstechnology-and-innovation
ENA to introduce mandatory spatiotemporal annotations
The European Nucleotide Archive database introduces mandatory spatiotemporal metadata for data submissions.
2023
updates-from-data-resources
EMBL Alumni Awards Announced for 2023
Two former EMBL scientists have been recognised for their outstanding contributions to the fields of science communication and multiple sequence alignment research, respectively.
2023
alumni
Genomic science to support conservation efforts: an interview with Lara Urban
Using long-read sequencing and machine learning approaches, EMBL alumna Lara Urban is making a difference in the field of One Health.
2023
perspectives
MGnify just got bigger – new data, new AI opportunities
EMBL-EBI's metagenomics data resource increases in size and supports groundbreaking AI tools for protein structure prediction.
2023
updates-from-data-resources
Large-scale study enables new insights into rare eye disorders
EMBL-EBI researchers use UK Biobank data to uncover new information about rare diseases of the eye.
2023
research-highlightsscience
New releases: InterPro 93.0 and InterProScan 5.61-93.0
InterPro now features hundreds of new methods integrated from partner databases, and InterProScan draws on over 38,000 entries. InterPro version 93.0 InterPro 93.0 integrates 300 new methods from the CDD (261), PANTHER (12), PROSITE profiles (17), SMART (9), TIGRFAMs (1) databases, and covers 81.7%…
2023
updates-from-data-resources
Open data for biodiversity: an EMBL-EBI 2022 round-up
As major biodiversity projects ramp up, EMBL-EBI enables genomic data sharing for all species.
2023
perspectivesscience
Latest Release of the Single Cell Expression Atlas
The Single Cell Expression Atlas (SCEA) now includes more datasets and species.
2023
updates-from-data-resources
Shedding light on rare diseases: open data and model organisms
Why open data from model organisms is essential for rare disease research.
2023
perspectivesscience
Europe PMC contributes to the Open Global Data Citation Corpus
The Open Global Data Citation Corpus will become a central place for research data citations, and include accession numbers supplied by Europe PMC.
2023
announcements
A human interactome to prioritise drug discovery
Researchers create a network of interacting proteins – or interactome – to aid drug discovery.
2023
research-highlightsscience
New Job Dispatcher website launched
EMBL-EBI’s Software Development and Operations team is delighted to announce the launch of a brand-new Job Dispatcher website, currently in development. The updated website provides a landing page for the Job Dispatcher services, making it easier for users to find and navigate services…
2023
updates-from-data-resources
Molecules to Ecosystems: Jo McEntyre on data services
Lab MattersPeople & Perspectives Jo McEntyre talks about data services, open data and a new era for research assessment.
2023
lab-matterspeople-perspectivesperspectives
New EU-funded Project: Fragment-Screen
Lab MattersScience & Technology EMBL is one of the partners of this project that aims to accelerate drug discovery and development, bringing in expertise from EMBL Grenoble and EMBL-EBI.
2023
lab-mattersscience-technology
Congratulations to the new Sanger Institute Director
EMBL-EBI congratulates Matt Hurles on being appointed as the new Director of the Wellcome Sanger Institute.
2023
announcements
Case study: AlphaFold uses open data and AI to discover the 3D protein universe
Open data played a pivotal role in the development of the AlphaFold AI. The same open principles now apply to AlphaFold predictions.
2023
perspectivesscience
Ensembl 109 has been released
Latest Ensembl and Ensembl Genomes releases bring updates to donkey and horse assemblies, and lots of new plants and metazoa.
2023
updates-from-data-resources
BlueRemediomics: harnessing marine microbes to promote a circular bioeconomy
Funding awarded for developing tools to harness marine microbiome data for biotechnological applications and ecosystem services.
2023
announcementsscience
Leveraging long-read sequencing for cancer genomics
Genomic sequencing and big data analysis are two novel technologies driving researchers’ understanding of the complexities of cancer.
2023
perspectivesscience
PDCM Finder – an open global cancer research platform for patient-derived cancer models
Aggregating clinical, genomic and functional data from patient-derived xenografts, organoids and cell lines
2023
updates-from-data-resources
Machine learning to identify and prioritise drug targets
Science & Technology Open Targets is using artificial intelligence and machine learning to identify and prioritise drug targets.
2023
sciencescience-technologytechnology-and-innovation
Darwin Tree of Life: first 500 genome assemblies released as project creates a buzz
Science & Technology We look back through some of the 2022 highlights from the Darwin Tree of Life project.
2023
perspectivessciencescience-technology
Molecules to Ecosystems: Rob Finn on the Microbial Ecosystems transversal theme
Lab MattersPeople & Perspectives Rob Finn, one of the co-chairs of the Microbial Ecosystems theme, discusses his work, the challenges of multidisciplinary research, and how the theme is already helping to promote the exchange of scientific ideas.
2023
lab-matterspeople-perspectives
New releases: InterPro 92.0 and InterProScan 5.60-92.0
InterPro version 92.0 and InterProScan 5.60-92.0 are now available. InterPro now features hundreds of new methods integrated from partner databases, and InterProScan draws on over 38000 entries.
2023
updates-from-data-resources
BOSS-RUNS: streamlining dynamic nanopore sequencing
Science & Technology A new method developed by EMBL-EBI researchers helps to streamline nanopore sequencing in real-time.
2023
research-highlightssciencescience-technology
EMBL-EBI databases considered critical to life sciences
Open data resources that enable global research and development recognised by the Global Biodata Coalition.
2022
announcementsscience
Spatial lung cell atlas offers insights into disease
Researchers have genetically profiled nearly 200,000 cells from lungs, mapping their precise locations in tissue to discover an unexpected new immune niche in our airways.
2022
research-highlights
First linked dataset on Pathogens Portal
The first cohort study linking data across categories was recently added on the Pathogens Portal Cohort Browser and is also accessible from the BioSamples browser. This pilot study comes from Erasmus Medical Centre through the ReCoDID project, one of the COVID-19 Data Platform supporting…
2022
updates-from-data-resources
EMBL-EBI appoints new Head of Technical Services
Andy Cafferkey takes on strategic role to help the institute respond to increasing demands from the global life science community.
2022
announcements
Developmental cell atlas uncovers new cell states
Unveiling a useful tool for understanding human lung development.
2022
research-highlightsscience
Genomic Data Infrastructure – integrating genomics into healthcare
EMBL-EBI supports new European Commission project set to support the use of genomics in research and healthcare.
2022
announcementsscience
Unleashing the biotechnology potential of euglenoids
An ambitious project to sequence the genomes of all known species of euglenoids will drive research on biofuels and sustainable foods.
2022
announcements
Building bioinformatics capacity in Latin America
EMBLetc The CABANA project was born out of a desire to strengthen bioinformatics capacity and accelerate data-driven biology in Latin America.
2022
Open Targets consortium welcomes Genentech as newest member
Open Targets announces that Genentech will become the seventh partner in the drug discovery and validation consortium.
2022
announcementsscience
Open science for climate justice
Our experts discuss the importance of open science for food security and preserving global biodiversity.
2022
perspectivesscience
New molecular microscopy uncovers how breast cancer spreads
Researchers have created a tool that maps in previously unseen detail how breast cancer develops and spreads.
2022
research-highlightsscience
AlphaFold applications – a community assessment
Researchers use social media to share findings on how useful AlphaFold predictions are for different applications.
2022
research-highlightsscience
AI4LIFE: AI models for bioimaging
Researchers across EMBL are helping to make artificial intelligence (AI) models for bioimaging analysis interoperable and openly available to the scientific community.
2022
announcementsscience
EMBL-EBI appoints Deputy Head of Research
Virginie Uhlmann will support the Interim Head of Research in managing the institute's computational research groups.
2022
announcements
Mapping the human brain: a global collaboration
NIH BRAIN Initiative to fund brain atlases, network coordination, and knowledge sharing to explore brain function research.
2022
announcementsscience
Compare experimental and predicted structures with PDBe-KB
You can now superpose AlphaFold models onto PDB structures at the touch of a button using the PDBe-KB aggregated views of proteins.
2022
updates-from-data-resources
Ensembl 108 has been released
We are pleased to announce the release of Ensembl 108, and the corresponding release of Ensembl Genomes 55 featuring changes in the human default tracks, new genomes in Ensembl Plants and Ensembl Metazoa, and the addition of mitochondrial annotation for Tasmanian devil. Genome assemblies and…
2022
updates-from-data-resources
New releases: InterPro 91.0 and InterProScan 5.59-91.0
We are pleased to announce the release of InterPro 91.0 and InterProScan 5.59-91.0
2022
updates-from-data-resources
ArrayExpress interface now retired
Data continues to be available in BioStudies.
2022
updates-from-data-resources
Natural language processing for rapid protein annotation
Over 40 million protein annotations have been added to the UniProt database using a Google Research natural language processing model.
2022
technology-and-innovation
Funding for researchers working on plastic recycling enzymes
EMBL-EBI’s MGnify data resource helps researchers find enzymes for novel applications.
2022
announcementsscience
Biodiversity Genomics Europe: addressing biodiversity loss through genomics
European experts gather to launch a project that aims to characterise and conserve life on Earth using DNA data.
2022
announcementsscience
Ardan Patwardhan receives Scientific Achievement Award
The Royal Microscopical Society recognises Ardan Patwardhan’s contributions to the field of electron microscopy.
2022
announcements
AlphaFold: where will the next AI breakthrough come from?
People & Perspectives Ewan Birney, Deputy Director General of EMBL and Director of EMBL-EBI, reveals the key factors that enabled AlphaFold to change the world of biology.
2022
people-perspectivesperspectivesscience
CNest: a new method for copy number variation analysis
Science & Technology A new method for the robust analysis of copy number variation and used UK Biobank data to identify links between genome and disease.
2022
research-highlightssciencescience-technology
New antibiotic resistance genes identified in tuberculosis
Science & Technology International consortium analyses the genetic sequences and antibiotic susceptibility of 10,000 global Mycobacterium tuberculosis isolates.
2022
research-highlightssciencescience-technology
New releases: InterPro 90.0 and InterProScan 5.57-90.0
InterPro version 90.0 and InterProScan 5.57-90.0 are now available. InterPro now features hundreds of new methods integrated from partner databases, and InterProScan draws on over 40000 entries
2022
updates-from-data-resources
Shining a light on how bacteria interact
Science & Technology Machine learning has helped researchers uncover new insights into how bacteria infect host cells.
2022
research-highlightssciencescience-technology
AlphaFold predicts structure of almost every catalogued protein known to science
Science & Technology AlphaFold database offers a look at 3D protein universe.
2022
sciencescience-technologytechnology-and-innovation
Latvian science benefits from prospect membership
Connections The first meeting of the Latvian Bioinformatics Forum points towards an even brighter future for the country’s role in European life sciences
2022
connectionsevents
The retron switch
Science & Technology EMBL researchers now understand the function of an elusive small DNA in bacteria and have developed a tool that can be used to better understand what might ‘switch on’ bacterial immune defences.
2022
sciencescience-technology
Uncharted territories in the human genome
Science & Technology Scientists identify previously unexplored gene segments to be added to human genome databases.
2022
research-highlightssciencescience-technology
Darwin Tree of Life at the Royal Society Summer Science Exhibition
A closer look at how genome sequencing is helping us protect biodiversity and our latest public engagement activities
2022
announcements
UKRI allocates funding for EMBL-EBI data resources
Funding set to support data resources for key areas of antimicrobial resistance, sustainable agriculture and biodiversity loss
2022
announcements
ArrayExpress interface to close
On 30 September 2022 the ArrayExpress interface will close. All datasets have now been migrated from ArrayExpress into the BioStudies ArrayExpress collection
2022
updates-from-data-resources
Supporting the African BioGenome Project to build bioinformatics capacity
ConnectionsLab Matters The African BioGenome Project and EMBL have signed a Memorandum of Understanding to support each other in building genomics and bioinformatics capacity across Africa
2022
announcementsconnectionslab-matters
Impact of DNA mutations on blood cell production uncovered
Science & Technology Researchers discover how DNA mutations change blood cell production and how this relates to ageing and cancer development.
2022
research-highlightssciencescience-technology
A machine learning approach for allocating gene function
Science & Technology Researchers in the Ensembl team are making the most of machine learning methods to speed up genome annotation pipelines
2022
sciencescience-technologytechnology-and-innovation
Fergal Martin – Eukaryotic Annotation Team Leader
Lab MattersPeople & Perspectives Fergal Martin discusses the importance of open access data and his work in different biodiversity initiatives
2022
lab-matterspeople-perspectives
Organisations should embrace open science faster – interview with Prof. Dame Janet Thornton
Lab MattersPeople & Perspectives Janet Thornton, the inaugural winner of the FEBS Journal Open Science Award, explains the importance and impact of open science.
2022
lab-matterspeople-perspectivesperspectives
Europe PMC: Harnessing the power of text mining to accelerate life sciences research
Science & Technology How text mining collaborations benefit our research, data resources, and the wider scientific community.
2022
sciencescience-technologytechnology-and-innovation
2.4 billion sequences now available in the latest MGnify protein database release
2.4 billion protein sequences are now available in the latest MGnify release including new annotations provided by Google AI
2022
updates-from-data-resources
Peter Harrison – Genome Analysis Team Leader
Lab MattersPeople & Perspectives Peter Harrison discusses the importance of data accessibility and his passion for biodiversity and agricultural genomics.
2022
lab-matterspeople-perspectives
Predicted complexes from ModelArchive now on PDBe-KB pages
New dataset of predicted protein complexes accessible through 3D-Beacons Network.
2022
updates-from-data-resources
Interpreting bioimages with deep learning
Science & Technology Virginie Uhlmann shares her tips for using deep learning for bioimage analysis in the life sciences.
2022
perspectivessciencescience-technology
Guy Cochrane appointed Executive Director of Global Biodata Coalition
The GBC is a coalition of life sciences and biomedical research funders that aims to optimise the funding and management of biodata resources worldwide. The organisation has two priority aims: to better coordinate and share approaches for efficient management and growth of the biodata…
2022
announcements
The MANE collaboration: working together to support genome science
Science & Technology Researchers from the MANE collaboration bring you the most comprehensive human genome annotation dataset to date.
2022
research-highlightssciencescience-technology
Welcome: John Lees
Lab MattersPeople & Perspectives John Lees joins EMBL-EBI as a Group Leader in Pathogen informatics and modelling.
2022
lab-matterspeople-perspectives
Latest Release of the Single Cell Expression Atlas
The latest Single Cell Expression Atlas (SCEA) release is here and features collaborations with DiscovAIR and the Fly Cell Atlas
2022
updates-from-data-resources
Genomic sequencing aids the global Tuberculosis fight
Science & Technology Zamin Iqbal and his team are working with researchers all over the globe to help put a stop to Tuberculosis
2022
perspectivessciencescience-technology
Darwin Tree of Life at EMBL-EBI: reaching the first major milestone
Science & Technology Our researchers highlight their contributions to the Darwin Tree of Life project and how new genome annotations helps to further biodiversity research
2022
announcementssciencescience-technology
Safeguarding African biodiversity through genomics
Science & Technology The African BioGenome Project aims to safeguard biodiversity and build bioinformatics capacity across Africa
2022
perspectivessciencescience-technology
Deep learning models help predict protein function
Science & Technology Deep learning models can improve protein annotations and has helped expand the Pfam database.
2022
perspectivessciencescience-technology
New Expression Atlas release in collaboration with PRIDE
New Expression Atlas release features differential-proteomics and baseline-proteomics experiments in collaboration with the PRIDE team at EMBL-EBI. This also includes new baseline DIA proteomics experiments as well as new differential proteomics datasets. To improve reproducibility,…
2022
updates-from-data-resources
New genetic data policy must promote biodiversity conservation
Science & Technology Scientists urge the adoption of a sensible international policy for digital sequence information.
2022
announcementssciencescience-technology
Pfizer joins the Open Targets consortium
Connections Open Targets, a consortium focused on drug target identification, prioritisation, and validation, announced today that Pfizer has joined as a partner.
2022
announcementsconnectionsscience
Learning from Deep Learning: the inspirational story behind AlphaFold
Science & Technology DeepMind visits EMBL Heidelberg to discuss current and future implications of Artificial Intelligence for life science research.
2022
sciencescience-technology
Artificial intelligence — a scientific game changer in 2021
Science & Technology The systematic application of AI in life sciences as in the AlphaFold algorithm for predicting protein structures has been named '2021 Breakthrough of the Year' by Science magazine.
2021
sciencescience-technology
Can data help feed a hungry world?
Science & Technology How genomics, open data, and multidisciplinary science can improve food security.
2021
sciencescience-technology
Making sense of bacterial DNA data
Science & Technology A vast, curated collection of bacterial genomes is now organised, searchable and open to the community.
2021
sciencescience-technology
Open data on the rise: the value of EMBL-EBI data resources
Lab MattersScience & Technology Independent study reveals that EMBL-EBI open data resources are critical for the life sciences.
2021
lab-mattersscience-technology
Harnessing the microbiome to improve meat production
Science & Technology International project uses biomolecular data to improve animal feed and make meat production more sustainable
2021
sciencescience-technology
Peer Bork honoured with Novozymes Prize and ISCB Senior Scientist Award
Lab MattersPeople & Perspectives Distinctions recognise Peer’s development and sharing of bioinformatics tools as well as his significant contributions to bioinformatics research, education, and services.
2021
lab-matterspeople-perspectives
EMBL scientists support malaria research
Science & Technology EMBL scientists support research on malaria by providing freely available data resources and using innovative experimental approaches. Our Course and Conference Office facilitates the exchange of knowledge in the field by hosting the annual BioMalPar conference.
2021
sciencescience-technology
SARS-CoV-2 curtails immune response in the gut
Science & Technology EMBL scientists, together with collaborators from Heidelberg University, have provided further evidence of the gut’s role in COVID-19.
2021
sciencescience-technology
Using metagenomic techniques to explore lichens
Science & Technology Researchers have used a metagenomics approach to piece together the genomes of yeasts found in wild lichens.
2021
sciencescience-technology
Wolfgang Huber becomes ISCB Fellow
EMBL AnnouncementsLab Matters The contribution of EMBL Group Leader and Senior Scientist Wolfgang Huber has been recognised by the International Society for Computational Biology
2021
embl-announcementslab-matters
Pfam releases structures for every protein family
Science & Technology Thousands of new protein structure models, prected using deep learning, now available to explore
2021
sciencescience-technology
The thousands of viruses living in your gut
Science & Technology Scientists identify more than 140 000 virus species in the human gut; more than half have never been seen before
2021
sciencescience-technology
Protein sequences provide clues to how SARS-CoV-2 infects cells
Science & Technology Researchers at EMBL Heidelberg have identified sequences in human proteins that might be used by SARS-CoV-2 to infect cells. They have discovered that the virus might hijack certain cellular processes, and they discuss potentially relevant drugs for treating COVID-19.
2021
sciencescience-technology
Insights into the new B.1.1.7 coronavirus lineage
Science & Technology A new lineage of coronavirus was first identified in the UK, but why is it spreading much more rapidly within the population?
2021
sciencescience-technology
Darwin Tree of Life: looking back on 2020
Science & Technology Despite restrictions, 2020 has been a busy year for the Darwin Tree of Life Project. We take a look at some of this year’s achievements and highlights.
2020
sciencescience-technology
Solving the protein structure puzzle
Science & Technology How artificial intelligence can help us solve the mysteries of the protein universe
2020
sciencescience-technology
Repurposing bioinformatics tools to tackle the pandemic
Science & Technology Bioinformaticians at EMBL-EBI and beyond are adapting computational tools to investigate coronavirus genomes and proteins.
2020
sciencescience-technology
Microbiomes help predict the future of the Atlantic
Connections Microbiomes, plastics, and connectivity – AtlantECO aims to understand the fabric of the Atlantic Ocean.
2020
connectionsscience
Repurposing drugs for a pan-coronavirus treatment
Science & Technology Scientists from the Beltrao Group at EMBL-EBI and collaborators identified drug targets common to SARS-CoV-2, SARS-CoV-1, and MERS-CoV, three pathogenic coronaviruses. They also found potential drugs that could be repurposed as COVID-19 treatments, and against emerging coronavirus strains in the…
2020
sciencescience-technology
Level up!
Lab Matters ARISE fellowships to offer first-ever comprehensive training for bioscience infrastructure operations
2020
lab-matters
Genome sequencing accelerates cancer detection
Science & Technology The Gerstung Group at EMBL-EBI and collaborators have developed a statistical model that analyses genomic data to predict whether a patient has a high or low risk of developing oesophageal cancer.
2020
sciencescience-technology
An organoid cell atlas to enhance biomedical research
EMBL AnnouncementsLab Matters EMBL-EBI is one of the eight European institutes involved in the Humanoid Cell Atlas initiative, a new open-access platform that combines single-cell profiling and organoid technology
2020
embl-announcementslab-matters
New clues to a 500-year old mystery about the human heart
Science & Technology An international team of scientists involving Ewan Birney's group has investigated the function of a complex mesh of muscle fibres that line the inner surface of the heart.
2020
sciencescience-technology
Bagpipe and Pokemon, or how not to name a human gene
Science & Technology The human genome harbours about 19 000 protein-coding genes, many of which still have no known function. As scientists unveil the secrets of our DNA, they come across novel genes that they need to refer to using a unique name. The Human Genome Organisation’s Gene Nomenclature Committee (HGNC) at…
2020
sciencescience-technology
Artificial intelligence finds patterns of mutations and survival in tumour images
Science & Technology Researchers have developed an artificial intelligence algorithm that uses computer vision to analyse tissue samples from cancer patients. The algorithm can distinguish between healthy and cancerous tissues, and can also identify patterns DNA and RNA changes in tumours.
2020
sciencescience-technology
Unparalleled inventory of the human gut ecosystem
Science & Technology An international team of scientists has collated all known bacterial genomes from the human gut microbiome into a single large database. Their work will allow researchers to explore the links between bacterial genes and proteins, and their effects on human health.
2020
sciencescience-technology
Funding to predict the risk of infectious disease outbreaks
Lab Matters European collaboration receives funding to explore risks and impact of future infectious disease outbreaks.
2020
lab-matters
Unpicking the complexity of DNA mutations
Science & Technology DNA damage caused by chemical mutagens is not repaired immediately and can create more genetic diversity in tumours.
2020
sciencescience-technology
Understanding the role of our genes in SARS-CoV-2 infections
Science & Technology EMBL scientists will contribute to the new German COVID-19 OMICS Initiative to study the biological mechanisms contributing to coronavirus infections. EMBL group leaders Jan Korbel and Oliver Stegle, who is also affiliated with the DKFZ Heidelberg, will coordinate the set-up of IT infrastructures…
2020
sciencescience-technology
DNA damage and faulty repair jointly cause mutations
Science & Technology DNA mutations are caused by a combination of DNA damage and repair, shows study by EMBL-EBI and collaborators.
2020
sciencescience-technology
Why share data during a pandemic?
Science & Technology In March 2020, planes were grounded, streets went quiet, and our lives changed forever. But while the world came to a halt, many scientists were ramping up their efforts to understand the new virus.
2020
sciencescience-technology
EMBL-EBI launches COVID-19 Data Portal
Science & Technology The new collaborative space will help scientists, public health and healthcare professionals around the world to fight the coronavirus pandemic.
2020
sciencescience-technology
Analysis of human genomes in the cloud
Science & Technology Scientists from EMBL present a tool for large-scale analysis of genomic data with cloud computing. Main advantages of the new tool, called Butler, are continuous system monitoring and its ability to self-heal in case of failure, allowing for 43% more efficient data processing than previous…
2020
sciencescience-technology
A classification tool for transcription factors
Science & Technology The software diffTF quantifies activity of transcription factors and predicts their mode of action
2019
sciencescience-technology
Machine learning finds critical phosphosites
Science & Technology Resource has implications for disease research
2019
sciencescience-technology
Science date: The Crick meets EMBL
People & Perspectives Crick and EMBL PhDs talk science over coffee
2019
people-perspectivesscience
Convention on the Rights of the Child stored in DNA
EMBL Announcements Children's rights stored in synthetic DNA
2019
embl-announcementsscience
Microbiomes take the stage at New Scientist Live
People & Perspectives On microbiomes, public engagement and not being boring
2019
eventspeople-perspectives
A tool to monitor tuberculosis
Science & Technology Funding awarded to EMBL-EBI for tuberculosis monitoring tool
2019
sciencescience-technology
B cells linked to immunotherapy
Science & Technology Immunotherapy: the role of B cells
2019
sciencescience-technology
Welcome: Isidro Cortés-Ciriano
People & Perspectives Exploring the cancer genomics labyrinth
2019
people-perspectivesscience
Understanding molecular mechanisms of ageing
Science & Technology Understanding how ageing works at a molecular level
2019
sciencescience-technology
Exploring the beauty of proteins
EMBL Announcements Schoolchildren get creative with 3D protein structures
2019
embl-announcementsscience
Use your coding superpowers for good
Lab MattersPeople & Perspectives Setting up a kids coding club - where to start
2019
lab-matterspeople-perspectives
A new home for biological images
Science & Technology The BioImage Archive - EMBL-EBI's first dedicated imaging data resource
2019
sciencescience-technology
How coding opens up scientific data
Science & Technology The increasing importance of code in the biological sciences
2019
sciencescience-technology
Life with the endangered kākāpō
Science & Technology Using genomics to help endangered species
2019
sciencescience-technology
Welcome: Jessica Vamathevan
Lab Matters Building bonds between academia and industry
2019
lab-matters
Comprehensive protein data for drug development
Lab Matters PDBe-KB - new data resource for protein structure and function launches
2019
lab-matters
Understanding early embryo development in mice
Science & Technology How organs form in a mouse embryo
2019
sciencescience-technology
Funding for bioinformatics technical infrastructure
Lab Matters Enhancing the world's bioinformatics infrastructure
2019
lab-matters
Most popular articles of the year: 2018
Lab Matters A collection of the most read articles from the EMBL news website in 2018
2019
lab-matters
Discovering new enzymes just got easier
Science & Technology EMBL-EBI industry case study: Biocatalysts
2018
sciencescience-technology
Algorithm identifies gene–environment relationships
Science & Technology New algorithm will enhance understanding of relationship between genotype and environmental factors
2018
sciencescience-technology
Welcome: Sarah Butcher
Lab Matters Building bridges between scientists and software developers
2018
lab-matters
Sanofi joins Open Targets
ConnectionsLab Matters Pharmaceutical company Sanofi strengthens drug targets discovery collaboration Open Targets
2018
connectionslab-matters
PhenoMeNal: an online portal for metabolomics
Science & Technology Complex metabolomics analyses in the cloud
2018
sciencescience-technology
Europe PMC now indexes preprints
Science & Technology Europe PMC adds preprints to its search
2018
sciencescience-technology
Leukaemia roots detectable years before diagnosis
Science & Technology Acute myloid leukaemia risk could be detected years before diagnosis
2018
sciencescience-technology
Personalised medicine: one data type is not enough
Science & Technology New computational method uses multi-omics analysis for personalised medicine
2018
sciencescience-technology
How wild species may benefit from mouse genetic data
Science & Technology Of mice and gorillas: using mouse data for conservation
2018
sciencescience-technology
PhD goals: why not start a company?
Lab MattersPeople & Perspectives EMBL-EBI PhD student launches start-up focusing on epigenetics and wellbeing
2018
lab-matterspeople-perspectives
Celgene joins Open Targets
ConnectionsLab Matters New partner strengthens drug discovery collaboration
2018
connectionslab-matters
New insights into the origins of cancer
Science & Technology What worms can tell us about cancer
2018
sciencescience-technology
PDX Finder – Free global portal for cancer models
Science & Technology Launch of the first free global online catalogue of PDX models
2018
sciencescience-technology
Welcome: Virginie Uhlmann
People & Perspectives New EMBL-EBI Group Leader will make sense of bioimaging data
2018
people-perspectivesscience
New method probes gene expression by cell location
Science & Technology What does a cell's location tell us?
2018
sciencescience-technology
Study identifies new diabetes genes
Science & Technology Network of genes linked to development of diabetes
2018
sciencescience-technology
EMBL’s first wetlab e-learning courses go live
EMBL Announcements EMBL’s training programme launches its first e-learning courses: introductions to optogenetics and CLEM
2018
embl-announcementsevents
Exploring 3D macromolecules in a flash
Science & Technology High resolution 3D protein structures in a giffy with PDBe
2017
sciencescience-technology
Takeda joins drug target discovery initiative
Lab MattersPeople & Perspectives Takeda joins pioneering public-private drug discover collaboration Open Targets
2017
lab-matterspeople-perspectives
BioModels performance boost, new model formats
Science & Technology New BioModels infrastructure supports significantly more model formats and offers improved search
2017
sciencescience-technology
How malaria springs to action in mosquitoes
Science & Technology Insights into the reproduction of Plasmodium parasites in mosquitoes reveal rapid and broad activity
2017
sciencescience-technology
A smart cabinet of curiosities
Science & Technology How open data is changing our pursuit of discovery
2017
sciencescience-technology
Welcome: Jan Kosinski
People & Perspectives EMBL’s new group leader based in Hamburg aims to create models of infection cycles
2017
people-perspectivesscience
UK pupils and scientists explore parasite problem
Lab Matters EMBL-EBI and collaborators engage schools in a large-scale genome decoding project
2017
eventslab-matters
Ten years of training at EMBL-EBI
Lab Matters International experts gather at EMBL-EBI to reflect on the future of bioinformatics training
2017
eventslab-matters
Computational models of cancer available
Science & Technology How patient-derived computational models can help researchers understand cancer
2017
sciencescience-technology
Welcome: Zamin Iqbal
People & Perspectives The Iqbal research group hopes to build a 'Google of bacteria' to help better interpret the genome
2017
people-perspectivesscience
Bioinformatics in Latin America
ConnectionsLab Matters EMBL-EBI supports bioinformatics training and capacity in Latin America
2017
connectionslab-matters
The sexual dimorphism dilemma
Science & Technology IMPC explains how much the sex of animals is misdirecting research results
2017
sciencescience-technology
Mouse genes could help decipher disease
Science & Technology EMBL-EBI and IMPC characterised over 3000 mouse genes, revealing new gene associations with disease
2017
sciencescience-technology
Open imaging data for biology
Science & Technology The Image Data Resource - prototype of the first open repository linking imaging and molecular data
2017
sciencescience-technology
HipSci: The human stem cell bank
Science & Technology Introducing one of the largest collections of high-quality human induced pluripotent stem cells
2017
sciencescience-technology
A race against the ageing clock
Science & Technology EMBL-EBI researchers identify mouse epigenetic clock that could help scientists understand ageing
2017
sciencescience-technology
Behind the scenes: Building EMBL’s Barcelona site
Lab Matters Silke Schumacher explains how the new EMBL site in Barcelona came into being
2017
lab-matters
Ageing: cell coordination breakdown
Science & Technology Researchers use single-cell sequencing to understand how cells age
2017
sciencescience-technology
Obituary: Anna Tramontano
Lab MattersPeople & Perspectives Anna Tramontano, bioinformatics pioneer and EMBL alumna, has passed away
2017
lab-matterspeople-perspectives
A tribute to Anna Tramontano
Lab MattersPeople & Perspectives Janet Thornton reflects on the contributions of EMBL alumna Anna Tramontano
2017
lab-matterspeople-perspectives
In remembrance of Anna Tramontano
People & Perspectives The research community mourns the passing of Anna Tramontano
2017
alumnipeople-perspectives
Building bioinformatics capacity in Africa
People & Perspectives EMBL alumna Nicola Mulder reflects on her pan-African bioinformatics project and its impact
2017
alumnipeople-perspectives
Genetic switches can change shape
Science & Technology EMBL scientists discovered that common mutations can change the shape of gene promoters
2017
sciencescience-technology
Buffering mechanism protects embryonic development
Science & Technology New mechanism revealed
2017
sciencescience-technology
Happy anniversary, PDBe!
Lab MattersScience & Technology Ewan Birney's nine "Structures of Christmas" celebrate 20 years of PDBe
2016
lab-mattersscience-technology
Improving data analysis in imaging mass spec
Science & Technology Open source bioinformatics method for finding metabolites makes experiments comparable across labs
2016
sciencescience-technology
Collaboration is beautiful
Science & Technology Where design meets bioinformatics, new scientific perspectives abound.
2016
sciencescience-technology
Bioinformatics with a bang
Lab Matters Unexpected adventures at EMBL LearningLAB focused on biodiversity
2016
lab-matters
Form follows function
Science & Technology 'The PDB plays a crucial role in structural biology research and development'
2016
sciencescience-technology
Pathways: Community management
People & Perspectives Scientific community manager, alumnus Aidan Budd, connects people with shared interests, values, goals
2016
alumnipeople-perspectives
Welcome: Georg Zeller
Science & Technology Team leader investigates how the gut microbiome could relate to human diseases
2016
sciencescience-technology
Just try!
Lab Matters German students visit EMBL-EBI on a tour to explore a new culture and different career paths
2016
lab-matters
Mapping early development
Science & Technology “Like getting hold of a microscope for the first time”
2016
sciencescience-technology
Poo transplants better understood
Science & Technology Stool transplants: finding the right match important, EMBL study shows
2016
sciencescience-technology
Foetus, or placenta?
Science & Technology Subtle genetic differences destine cells to placenta or animal, very early in embryo development
2016
sciencescience-technology
DREAM shadows: chasing down disease networks
Science & Technology “It’s a bit like drawing a picture of an intricate object just by looking at its shadow on the wall."
2016
sciencescience-technology
What is the value of open data?
Lab Matters Independent analysis of EMBL-EBI underscores the value and impact of open data in the life sciences
2016
lab-matters
The carbon hijacking network
Science & Technology Plankton network linked to ocean's biological carbon pump revealed
2016
sciencescience-technology
Bioinformatics training in Africa
Connections GOBLET initiative supports pan-African bioinformatics trainers in Cape Town.
2015
connectionsevents
Drugging bacteria
Science & Technology Commonly used diabetes drug metformin impacts gut bacteria more than disease itself
2015
sciencescience-technology
Building a career in bioinformatics
Lab Matters Annual EMBL-EBI Open Day showcases bioinformatics services, training and career opportunities.
2015
eventslab-matters
Unpacking embryonic pluripotency
Science & Technology Embryology, genomics and bioinformatics combine to identify factors regulating mammalian pluripotency.
2015
sciencescience-technology
Enzyme research made easier
Science & Technology Enzyme Portal makes it easier to explore all enzyme-related data in EMBL-EBI’s public resources.
2015
sciencescience-technology
Mini DNA sequencer tests true
Science & Technology Evaluation of MinION™ sequencer finds performance and reliability consistently good.
2015
sciencescience-technology
A lasting legacy
Science & Technology 1000 Genomes Project pushed technologies and knowledge forward to understand what is 'normal' human genetic variation
2015
sciencescience-technology
Joining forces for events
Connections EMBL-Wellcome Genome Campus events collaboration showcases open, application-based science.
2015
connectionsevents
Symposium sails sea of knowledge
Connections Insights from organisers of upcoming EMBO|EMBL Aquatic Microeukaryotes symposium.
2015
connectionsevents
EMBL-EBI training news
EMBL Announcements Highlights from EMBL-EBI’s Training Programme: Open Day, revamped webpages, free webinar series.
2015
embl-announcementsevents
Clearing a path for cancer research
Science & Technology New computational method to study biological signalling networks in healthy and cancer cells.
2015
sciencescience-technology
Welcome: Moritz Gerstung
Lab MattersPeople & Perspectives New group explores why patients with same cancer exhibit unique constellations of genetic mutations.
2015
lab-matterspeople-perspectives
Transitions
Lab MattersPeople & Perspectives Janet Thornton reflects on her time as Director of one of Europe’s fastest growing research institutes.
2015
lab-matterspeople-perspectives
First, find your membrane
Science & Technology Collaboration between scientists reveals collaboration between lipids.
2015
sciencescience-technology
Welcome: Theodore Alexandrov
People & Perspectives A mathematician who got ‘sucked in’ to biological problems, meet new team leader Theodore Alexandrov.
2015
people-perspectivesscience
From patients to the lab (and back)
Science & Technology Multidisciplinary research provides clues to new treatments for deadly form of leukaemia in children
2015
sciencescience-technology
Know your cells
Science & Technology How T-cells are trained on what not to kill
2015
sciencescience-technology
The genome in the cloud
Science & Technology Jan Korbel and colleagues publish commentary on risks and rewards of genome cloud computing.
2015
sciencescience-technology
Large-scale genetic analysis made easier
Science & Technology Researchers at EMBL-EBI speed up complex GWAS analyses with new method and algorithm.
2015
sciencescience-technology
EMBL-EBI joins CERN openlab
Lab Matters CERN openlab enters a new phase, expanding to include EMBL-EBI and other public research organisations.
2015
lab-matters
A powerful HMMER for data mining
Lab Matters HMMER – a fast, sensitive search tool – helps find sequence relationships deep in evolutionary time.
2015
lab-matters
ELIXIR accelerates
Lab Matters ELIXIR receives major Horizon 2020 funding to ‘EXCELERATE' activities over the next four years.
2015
lab-matters
Oceans endeavour charts 40 million genes
Science & Technology Tara Oceans results reveal climate change insights, and a treasure trove of novel species and genes.
2015
sciencescience-technology
PDBe launches new website
Lab Matters In their quest to make structural biology more accessible, PDBe launches a new website.
2015
lab-matters
CORBEL: bridging research infrastructures
Lab Matters Major EU funding for CORBEL, facilitating access to data and biological imaging facilities.
2015
lab-matters
GWAS Catalog moves to EMBL-EBI
Lab Matters GWAS Catalog, originally developed by the NHGRI in the US, moves to EMBL-EBI.
2015
lab-matters
New Joint Directors of EMBL-EBI
Lab Matters Rolf Apweiler and Ewan Birney appointed Joint Directors of EMBL-EBI, as Janet Thornton steps down.
2015
lab-matters
Bioinformatics services: Winter 2015
Lab Matters A quick round-up of the latest EMBL-EBI service releases.
2015
lab-matters
500,000 binary interactions… and growing
Lab Matters Building and visualising protein-interaction networks is easier and more accurate thanks to IntAct.
2015
lab-matters
How to crowdsource a paper
Science & Technology Tried and tested do's and don'ts of crowdsource writing.
2015
sciencescience-technology
Why is a dolphin not a cat?
Science & Technology How repurposing non-coding elements in the genome gave rise to the great ‘mammalian radiation’.
2015
sciencescience-technology
Beyond COMPARE
Lab Matters New project aims to speed up detection and response to disease outbreaks using genome technology.
2015
lab-matters
Relaunching YourGenome.org
Lab Matters EMBL-EBI supports relaunch of yourgenome.org, to bring genetics advances to a wider audience.
2015
lab-matters
What makes a mosquito deadly?
Science & Technology Genome-based insights into evolution of malaria-carrying Anopheles mosquitoes.
2014
sciencescience-technology
Record parasitic worm dataset
Science & Technology Largest collection of helminth genomic data ever assembled, in new open-access WormBase ParaSite.
2014
sciencescience-technology
Welcome: Judith Zaugg
People & Perspectives Whether it’s information or people, the art of connecting is key to new group leader Judith Zaugg
2014
people-perspectivesscience
Big (Protein) Data to Knowledge
Lab Matters 'Big Data to Knowledge' project by UCLA, Scripps and EMBL-EBI to transform protein data to knowledge.
2014
lab-matters
Computational modelling resource
Science & Technology New, open repository helps researchers share computational models of disease.
2014
sciencescience-technology
European Variation Archive launches
Science & Technology European Variation Archive makes it easier to explore detailed information about genetic variation.
2014
sciencescience-technology
Job dispatched
Lab Matters How does EMBL-EBI run millions of jobs for its users while moving its two large data centres?
2014
lab-matters
Music of the spheres
Lab Matters Music, bubbles and DNA: a collaborative project brings artist and scientist together
2014
lab-matters
Awards & Honours
Lab Matters EMBL scientists regularly receive prestigious awards - meet the latest honourees
2014
lab-matters
Blog roundup: September
Lab Matters Pathfinding – poetic and practical – was a common theme in blogs from the EMBL network.
2014
lab-matters
EU Codefest
Pooling programming and problem-solving expertise in bioinformatics at EMBL-EBI.
2014
events
Genotype to phenotype mapping course
EMBL-EBI hosts successful first EMBO Practical Course in Genotype to Phenotype Mapping.
2014
events
Major advance in stem cell technology
Science & Technology Researchers produce pristine stem cells, which can be precisely changed into clinically relevant cell types.
2014
sciencescience-technology
Gibbon genome joins Ensembl
Science & Technology Gibbon genome gives insights into evolution of this singing, swinging, tree-dwelling ape.
2014
sciencescience-technology
RNAcentral Station
Science & Technology RNAcentral is the first unified resource for all types of non-coding RNA data.
2014
sciencescience-technology
How do animals become domesticated?
Science & Technology Bronwen Aken discusses what research into the rabbit genome reveals about animal domestication.
2014
sciencescience-technology
New, improved human genome
Science & Technology Ensembl has incorporated a vast amount of knowledge into a fully annotated reference human genome
2014
sciencescience-technology
Celebrating 20 years of bioinformatics
Lab Matters EMBL-EBI’s anniversary celebration: blue skies thinking, Robin Ince and a biology-themed cake
2014
alumnilab-matters
Back to school
Lab Matters School ambassadors show next generation that scientists are more ‘role model’ than ‘mad professor’
2014
lab-matters
Awards & Honours
Lab Matters EMBL scientists regularly receive prestigious awards - meet the latest honourees
2014
lab-matters
The shape of things to come
Science & Technology New ways of handling and distributing data at PDBe to tackle ever larger and more complex proteins
2014
sciencescience-technology
Capturing marine biodiversity
Science & Technology Data from first ever worldwide Ocean Sampling Day will be shared via EMBL-EBI resources this autumn.
2014
sciencescience-technology
Cross-Channel collaboration
Connections Teaming up in Ireland to address big challenges in biology
2014
connectionsevents
How immune cells use steroids
Science & Technology Genome Campus researchers discover that some immune cells turn themselves off by producing a steroid.
2014
sciencescience-technology
Tsetse fly genome sequenced
Science & Technology Tsetse fly genome sequenced; scientists hope to find new ways to control sleeping sickness.
2014
sciencescience-technology
Bacterial balance that keeps us healthy
Science & Technology The thousands of bacteria, fungi and other microbes that live in our gut are essential contributors to our good health. They break down toxins, manufacture some vitamins and essential amino acids, and form a barrier against invaders. A study published today in Nature shows that, at 3.3 million,…
2010
sciencescience-technology
Membrane-coat proteins: bacteria have them too
Science & Technology Although they are present almost everywhere, on land and sea, a group of related bacteria in the superphylum Planctomycetes-Verrucomicrobia-Chlamydiae, or PVC, have remained in relative obscurity ever since they were first described about a decade ago. Scientists at the European Molecular Biology…
2010
sciencescience-technology
Open access drug discovery database launches with half a million compounds
Science & Technology ChEMBLdb, a vast online database of information on the properties and activities of drugs and drug-like small molecules and their targets, launches today with information on over half a million compounds. The data lie at the heart of translating information from the human genome into successful new…
2010
sciencescience-technology
International consortium announces the 1000 Genomes Project
Lab Matters Drawing on the expertise of multi-disciplinary research teams, the map developed by the 1000 Genomes Project will provide a view of biomedically relevant DNA variations at a resolution unmatched by current resources. The European Bioinformatics Institute (EBI), working with long-term collaborator…
2008
lab-matters
The East Wing and a new dawn for the EMBL-EBI
Lab Matters The European Molecular Biology Laboratory’s European Bioinformatics Institute (EMBL-EBI) officially opens its new East Wing today with a reception for prominent guests. The East Wing will be jointly opened by Ian Pearson, Minister of State for Science and Innovation, UK, and Robert-Jan Smits,…
2007
lab-matters
CiteXplore
Lab MattersScience & Technology Today the European Molecular Biology Laboratory’s European Bioinformatics Institute (EMBL-EBI) launches CiteXplore, a new freely accessible literature resource service. Biological researchers require two crucial sources of information: scientific literature published in peerreviewed…
2006
lab-mattersscience-technology
A brighter future for Europe’s favourite molecular biology software package
ConnectionsLab Matters EMBOSS, the European Molecular Biology Open Software Suite, has received a vital funding boost from the UK Biotechnology and Biological Sciences Research Council (BBSRC) that will guarantee its continued maintenance under an open source license for the next three years. This ends two years of…
2006
connectionslab-matters
European Commission funds EBI to do new research on synergies between bioinformatics and medical informatics
ConnectionsLab Matters The European Commission has selected the EBI to coordinate a project that will stimulate and explore synergies between bioinformatics (the science of storing, retrieving and analysing large amounts of biological information) and medical informatics (the science of processing, sharing and using…
2005
connectionslab-matters
Double recognition of EBI scientists by the ISCB
EMBL Announcements The International Society for Computational Biology has named two scientists from the European Bioinformatics Institute as the winners of its awards for 2005. Janet Thornton wins the Senior Scientist Accomplishment Award while the Overton Prize goes to Ewan Birney. Thomas Lengauer, the ISCB’s…
2005
embl-announcements
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