2018

28 February 2023 Decorative image showing mice silhouettes in different colours.

Shedding light on rare diseases: open data and model organisms

Why open data from model organisms is essential for rare disease research.

2023

perspectivesscience

22 February 2023 Person sitting on a chair

Molecules to Ecosystems: Jo McEntyre on data services

Jo McEntyre talks about data services, open data and a new era for research assessment.

LAB MATTERS PEOPLE & PERSPECTIVES

2023

lab-matterspeople-perspectivesperspectives

14 July 2022 Visualising the ocean below and above surface, showing several species and giving written details on the ocean microbiome composition

Visualising the ocean below and above surface, showing several species and giving written details on the ocean microbiome composition

Priorities for ocean microbiome research

Microbial communities play essential roles in ocean ecology and planetary health. A recent publication highlights priorities for understanding and protecting ocean microbiomes.

SCIENCE & TECHNOLOGY

2022

sciencescience-technology

13 July 2022 Decorative image showing a double helix DNA road and with what look like road signs.

Uncharted territories in the human genome

Scientists identify previously unexplored gene segments to be added to human genome databases.

SCIENCE & TECHNOLOGY

2022

research-highlightssciencescience-technology

22 April 2022 Portrait picture of a woman

“If you want science to move forward, you have to share it”

EMBO Director Fiona Watt discusses preprints, data sharing, and evaluation in light of EMBL’s new Open Science policy

LAB MATTERS PEOPLE & PERSPECTIVES

2022

lab-matterspeople-perspectives

19 December 2018 The robots used during the experiments. The shape of this particular swarm is a hand-made illustration of the technique. PHOTO: reprinted with permission from AAAS

The robots used during the experiments. The shape of this particular swarm is a hand-made illustration of the technique. PHOTO: reprinted with permission from AAAS

Hundreds of tiny robots grow bio-inspired shapes

Scientists build self-organising features into robot swarms to study shape formation

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

18 December 2018

Design thinking

EMBL’s Design Team Lead on translating scientific discoveries into visual designs

LAB MATTERS PEOPLE & PERSPECTIVES

2018

lab-matterspeople-perspectives

17 December 2018 Mouse skin samples of the rare genetic skin disease amyloidosis, before light treatment (left) and after treatment (right). The arrows indicate aggregates of debris, which cause the skin to become rough and uncomfortable. Upon treatment these aggregates are reduced, allowing the skin to heal. IMAGES: Paul Heppenstall and Linda Nocchi / EMBL

Mouse skin samples of the rare genetic skin disease amyloidosis, before light treatment (left) and after treatment (right). The arrows indicate aggregates of debris, which cause the skin to become rough and uncomfortable. Upon treatment these aggregates are reduced, allowing the skin to heal. IMAGES: Paul Heppenstall and Linda Nocchi / EMBL

Using light to stop itch

EMBL researchers have found a way to stop itch with light in mice

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

17 December 2018 Stephan Schiffels is a group leader at the Max Planck Institute for the Science of Human History in Jena, Germany. PHOTO: MPI-SHH

Reconstructing the human past

What genetics can tell us about the structure of ancient human populations

PEOPLE & PERSPECTIVES

2018

eventspeople-perspectives

10 December 2018 artistic impression of the double helix structure of DNA

Model to predict prostate cancer progress

Cancer researchers have developed a computer model to predict the course of disease for prostate cancer

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

7 December 2018 Members of GeneCore Jonathan Landry, Vladimir Benes and Anja Telzerow.

DIY Biology kits: what’s really growing inside?

EMBL’s GeneCore steps up to discover the facts and settle disputes

LAB MATTERS

2018

lab-matters

6 December 2018 A network of interacting RNAs and proteins is active in each of our cells.

New ways to look at protein-RNA networks

Researchers develop new method to analyse the entire protein-RNA network of the cell

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

5 December 2018 Silke Schumacher, EMBL Director of International Relations, and Tamás Bíró, HCEMM Director General, at the signing of the Partnership Agreement. PHOTO: NRDI Office, Hungary

Silke Schumacher, EMBL Director of International Relations, and Tamás Bíró, HCEMM Director General, at the signing of the Partnership Agreement. PHOTO: NRDI Office, Hungary

New EMBL Partnership in Hungary

EMBL partners with the Hungarian Centre of Excellence for Molecular Medicine

CONNECTIONS LAB MATTERS

2018

connectionslab-matters

3 December 2018 Lab technician working on enzyme

Discovering new enzymes just got easier

EMBL-EBI industry case study: Biocatalysts

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

30 November 2018 Surface views of 3D reconstructions of the TBEV sub-viral particles.

Translating blue-sky research into the clinic

What does it take to create a vaccine or improve cancer therapies?

LAB MATTERS SCIENCE & TECHNOLOGY

2018

lab-mattersscience-technology

28 November 2018 EIPOD postdocs work together as part of the Corporate Summer School.

Science in industry

EMBL postdocs discover industry-led research opportunities at the Corporate Summer School

LAB MATTERS

2018

eventslab-matters

27 November 2018 European Researchers' Night

Night of research, culture and treats

The EMBL Teens reporters discover the European Researchers’ Night

LAB MATTERS

2018

eventslab-matters

26 November 2018 A new algorithm identifies multiple gene–environment relationships

Algorithm identifies gene–environment relationships

New algorithm will enhance understanding of relationship between genotype and environmental factors

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

26 November 2018 Sarah Butcher EMBL-EBI Technical Team Leader

Welcome: Sarah Butcher

Building bridges between scientists and software developers

LAB MATTERS

2018

lab-matters

22 November 2018 Portrait of Nina Kathe

Ambition and talent

Nina Kathe, Winner of the EU Contest for Young Scientists visits EMBL

LAB MATTERS

2018

eventslab-matters

21 November 2018

Communities building collections

The EMBL Archive is open for business!

LAB MATTERS

2018

lab-matters

19 November 2018 Molecular and behavioural consequences of the SETD5 mutation. IMAGE: Isabel Chew

Molecular and behavioural effects of SETD5 mutation

Scientists uncover effects of mutation that can cause autism and intellectual disability

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

16 November 2018

An in silico hope for biology: machine learning

How EMBL scientists are using machine learning to advance biology

LAB MATTERS SCIENCE & TECHNOLOGY

2018

lab-mattersscience-technology

15 November 2018 Top view picture of modified and natural invagination in a tissue

Controlling organ growth with light

The De Renzis group investigated invagination, the first step of organ development in embryos.

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

9 November 2018 3D printing anatomical models.

In the flesh: translating 2D scans into 3D prints

Translating 2D hospital scans into 3D prints is informing patients and aiding surgeons

SCIENCE & TECHNOLOGY

2018

alumniscience-technology

8 November 2018 Darwin Tree of Life Project

Genomes of all known UK species to be sequenced

Genomes of 66,000 UK species to be sequenced in global effort to sequence all known eukaryotic species

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

7 November 2018 Blood cells

New insights into the regulation of haemostasis

EMBL scientists investigate the structure of a key protein involved in blood clotting

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

2 November 2018 RNA-binding protein

Catching up on protein dynamics

The Hentze Lab enhanced a RNA-interactome capture technique to pave the way towards medical progress

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

31 October 2018 Infographic on how X-RAY crystallography works. IMAGE: Tobias Wüstefeld

Time-resolved X-ray crystallography simplified

Speeding up time-resolved X-ray crystallography with EMBL beamline P14

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

31 October 2018 Internal anatomy of the marine worm’s head.

A worm’s sense of the world

EMBL researchers discover that four organs in a marine worm’s head can sense different chemicals

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

30 October 2018 Sanofi logo on blue background

Sanofi joins Open Targets

Pharmaceutical company Sanofi strengthens drug targets discovery collaboration Open Targets

CONNECTIONS LAB MATTERS

2018

connectionslab-matters

29 October 2018 James Sharpe, the head of EMBL Barcelona, speaks at the Inauguration Symposium.

¡Hola, Barcelona!

EMBL Barcelona invites locals to celebrate its Inauguration Symposium

CONNECTIONS

2018

connectionsevents

26 October 2018 Open access (OA) logo

The future of scientific publishing

Ioanna Ydraiou and Bernd Pulverer spoke about their view of challenges and opportunities of OA.

LAB MATTERS

2018

lab-matters

24 October 2018 Insulin receptor structural biology. IMAGE: Felix Weis and Christoph Müller / EMBL

More effective insulin thanks to first 3D image

New study reveals how to make therapeutic insulins more effective than they currently are

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

23 October 2018

Exploring cell identity by mapping genetic networks

ERC grantees Wolfgang Huber and Oliver Stegle share their vision for the next 10 years

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

22 October 2018 An 88% complete model of human hemoglobin (PDB id 5ni1) built de novo by ARP/wARP into a 3.2 Å cryo-EM map. IMAGE: Victor Lamzin/EMBL

ARP/wARP 8.0 released

Researchers at EMBL Hamburg have released the next generation of their ARP/wARP software

LAB MATTERS SCIENCE & TECHNOLOGY

2018

lab-mattersscience-technology

19 October 2018 A group of young students in front of the EMBL site in Hamburg.

Guiding young scientists

17 young scientists experienced hands-on training at EMBL Hamburg.

CONNECTIONS

2018

connectionsevents

16 October 2018

Deleting genes to study how germ cells are born

How embryonic stem cells develop into the germ line

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

15 October 2018

How cellular signalling controls chromatin modification. IMAGE: Aleksandra Krolik/EMBL

Transcription factors controlled by DNA sequence

EMBL scientists gain mechanistic insights into how cellular signalling controls gene regulation

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

9 October 2018 Wendy Bickmore. PHOTO: Massimo Del Prete

EMBL in the UK: Wendy Bickmore

Meet Wendy Bickmore, Director of the MRC Human Genetics Unit, who spoke at the EMBL in the UK event

PEOPLE & PERSPECTIVES

2018

alumnipeople-perspectives

8 October 2018

Gareth Griffiths and Rein Aasland at the CASE awards.

Excellent alumni

EMBL alumni Gareth Griffiths and Rein Aasland receive the 2018 “Volunteer of the Year” award

CONNECTIONS

2018

alumniconnections

5 October 2018 Marja Makarow. PHOTO: Etienne Ansotte/EC

EMBL in Finland: Marja Makarow

Scientists in Finland met to share ideas and discover research opportunities

CONNECTIONS

2018

alumniconnections

4 October 2018 Lola Ledesma. PHOTO: Jose Antonio Pérez/CBMSO

EMBL in Spain: Lola Ledesma

EMBL alumni and researchers working throughout Spain met in Madrid

CONNECTIONS

2018

alumniconnections

1 October 2018 Studying the molecular features of ageing in human blood stem cells showed that as blood stem cells age, their sugar metabolism increases. IMAGE: Campbell Medical Illustration

Studying the molecular features of ageing in human blood stem cells showed that as blood stem cells age, their sugar metabolism increases. IMAGE: Campbell Medical Illustration

Ageing is visible in the way cells use glucose

Researchers from EMBL and Heidelberg University unveil the molecular mechanisms of ageing

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

27 September 2018

Looking for life using geobiology

Meet the organisers of EMBO’s first course on molecular geobiology

SCIENCE & TECHNOLOGY

2018

eventsscience-technology

20 September 2018

Promega joins EMBL’s Corporate Partnership Programme

EMBL and Promega collaborate to train young scientists

CONNECTIONS LAB MATTERS

2018

connectionslab-matters

17 September 2018 The retromer complex

Solving the structure of retromer

Retromer’s 3D structure improves understanding of cellular sorting and packaging

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

13 September 2018 IMAGE: Manon Boschard

X-rays reveal surprising shape of scaffolding protein

X-ray experiments show that scaffolding protein PDZK1 has a L-shaped conformation

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

10 September 2018 A dynamic protein atlas of a human cell. IMAGE: Aleksandra Krolik/EMBL

First interactive model of human cell division

Real-time tracking of proteins during mitosis is now possible using a 4D computer model

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

5 September 2018

€17 million fund to power European detection and imaging innovation pipeline

ATTRACT initiative will fund 170 breakthrough detection and imaging ideas with market potential

CONNECTIONS LAB MATTERS

2018

connectionslab-matters

30 August 2018 PhenoMeNal logo on binary data stream

PhenoMeNal: an online portal for metabolomics

Complex metabolomics analyses in the cloud

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

29 August 2018 During cell division, cohesin directly engages DNA (purple) and holds the replicated chromosome together. IMAGE: Nasser Rusan/National Institutes of Health

During cell division, cohesin directly engages DNA (purple) and holds the replicated chromosome together. IMAGE: Nasser Rusan/National Institutes of Health

Cohesin: a glue for DNA

EMBL scientists discover how a component of the cohesin ring binds DNA

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

27 August 2018 Robbert Dijkgraaf, director of the Institute for Advanced Study in Princeton, US

The usefulness of useless knowledge

Theoretical physicist Robbert Dijkgraaf discusses the importance of curiosity-based research

PEOPLE & PERSPECTIVES

2018

eventspeople-perspectives

23 August 2018 Single cells and DNA code

New approach for testing cancer drug response

Large-scale systematic analysis explores how inherited genome affects drug response of cancer cells

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

22 August 2018

Welcome: Jim Swoger

New head of the Mesoscopic Imaging Facility at EMBL Barcelona will help scientists visualise nature

PEOPLE & PERSPECTIVES

2018

people-perspectivesscience

16 August 2018 Researchers in the life sciences are encouraged to apply for ATTRACT initiative seed funding

Open call for detector and imaging tech projects

The ATTRACT initiative, of which EMBL is a partner, has launched an open call for seed funding

EMBL ANNOUNCEMENTS LAB MATTERS

2018

embl-announcementslab-matters

14 August 2018 EMBL lab day 2018 - Key visual for Iain Mattaj's staff farewell event

Celebrating science

The EMBL community, past and present, gather for special events around Lab Day 2018

LAB MATTERS

2018

eventslab-matters

7 August 2018 Group picture of the students and coordinators of the second edition of ‘Summer in Science’ at EMBL Rome. PHOTO: Berta Carreño/EMBL

Summer in Science 2018

EMBL Rome opens its labs for students to get their first real taste of science

LAB MATTERS

2018

eventslab-matters

3 August 2018 Optical section of a ‘gastruloid’ – an embryonic organoid made from mouse embryonic stem cells and stained for E-Cadherin (red), marking cell outlines and nuclei (blue). IMAGE: Vikas Trivedi/EMBL

Optical section of a ‘gastruloid’ – an embryonic organoid made from mouse embryonic stem cells and stained for E-Cadherin (red), marking cell outlines and nuclei (blue). IMAGE: Vikas Trivedi/EMBL

Welcome: Vikas Trivedi

An engineer’s approach to understanding morphogenesis

PEOPLE & PERSPECTIVES

2018

people-perspectivesscience

2 August 2018

Humans of EMBL: Outreach

Discover how EMBLers across all sites share their passion for science

LAB MATTERS PEOPLE & PERSPECTIVES

2018

lab-matterspeople-perspectives

1 August 2018 Global warfare between bacteria and fungi in soil. IMAGE: Hildebrand/Krolik in collaboration with Campbell Medical Illustration/EMBL

Global warfare between bacteria and fungi in soil. IMAGE: Hildebrand/Krolik in collaboration with Campbell Medical Illustration/EMBL

Understanding soil through its microbiome

First global survey of soil genomics reveals a war between fungi and bacteria

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

26 July 2018

The proteins behind hungry cells

EMBL researchers visualise the proteins needed to capture molecules and bring them into a cell

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

26 July 2018 Acrylic painting of couple made of proteins

Art meets structural biology

The Protein Data Bank in Europe celebrates its schools art project with its largest exhibition yet

LAB MATTERS

2018

lab-mattersscience

17 July 2018 Facts and figures from Europe PMC

Europe PMC now indexes preprints

Europe PMC adds preprints to its search

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

12 July 2018 Artistic 3D rendering of the dual spindle in the mammalian zygote. IMAGE: Cartasiova, Hossain, Reichmann, Ellenberg/EMBL

Parental chromosomes kept apart during first division

Mammalian life begins differently than we thought

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

11 July 2018 IMAGE: Aleksandra Krolik, EMBL

Maternal bacteria persistent in newborns

Scientists show how bacteria and other microorganisms are passed on from mother to child

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

10 July 2018 Leukaemia blood cells

Leukaemia roots detectable years before diagnosis

Acute myloid leukaemia risk could be detected years before diagnosis

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

9 July 2018 Miki Ebisuya at EMBL Barcelona

Welcome: Miki Ebisuya

New group leader at EMBL Barcelona creates artificial biological systems to study animal development

PEOPLE & PERSPECTIVES

2018

people-perspectivesscience

6 July 2018 E. coli bacteria colored in heat gradient. IMAGE: Aleksandra Krolik / EMBL

Melting bacteria to decipher antibiotic resistance

EMBL scientists investigate how bacteria melt to study their reaction to drugs

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

4 July 2018

Combining antibiotics changes their effectiveness

Combining antibiotics with each other, non-antibiotic drugs or food additives can alter their effectiveness

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

29 June 2018 Architectural comparison of the Chlamydomonas reinhardtii NPC (left) and the human NPC (right). IMAGE: Shyamal Mosalaganti/EMBL

Algal nuclear pore complex revealed

EMBL scientists reveal NPC architecture of algae

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

27 June 2018 PHOTO: Photolab/EMBL

Powering up

Alumni share how joining EMBL’s IT team was a career upgrade

PEOPLE & PERSPECTIVES

2018

alumnipeople-perspectives

26 June 2018 Mutations at the amino acid shown in orange (isoleucine 38) lead to reduced susceptibility to the drug. IMAGE - Stephen Cusack, EMBL

Flu’s response to new drug explored

EMBL scientists investigate how influenza virus responds to new drug treatment

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

25 June 2018 New method using silica-based columns simplifies the extraction of DNA – and RNA-protein complexes. IMAGE: Adobe stock

New way to isolate DNA- and RNA-protein complexes

EMBL researchers develop method that simplifies the isolation of DNA- and RNA- protein complexes

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

22 June 2018

Miniature testing of drug pairs on tumour biopsies

Combinations of cancer drugs can be quickly and cheaply tested using a novel microfluidic device

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

21 June 2018

2019 EMBL course and conference sneak preview

The programme promotes education, collaboration and cutting-edge research

LAB MATTERS

2018

eventslab-matters

20 June 2018

New insights into Turing patterns

EMBL scientists extend Turing’s theory to help understand how biological patterns are created

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

20 June 2018

Personalised medicine: one data type is not enough

New computational method uses multi-omics analysis for personalised medicine

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

19 June 2018

EMBL in Italy: Kristina Havas-Cavalletti

More than 80 attendees gathered at the EMBL in Italy event at the FIRC Institute of Molecular Oncology (IFOM) in Milan

PEOPLE & PERSPECTIVES

2018

alumnipeople-perspectives

18 June 2018 Three examples of the tissue shapes the team created. The black and white square, circle and triangle on the left correspond to the cells that were illuminated. On the right, three fruit fly embryos are shown in cyan, magenta and yellow, demonstrating how the illuminated cells folded inwards after the light-activation. IMAGE: Stefano De Renzis, EMBL

Three examples of the tissue shapes the team created. The black and white square, circle and triangle on the left correspond to the cells that were illuminated. On the right, three fruit fly embryos are shown in cyan, magenta and yellow, demonstrating how the illuminated cells folded inwards after the light-activation. IMAGE: Stefano De Renzis, EMBL

Constructing new tissue shapes with light

EMBL researchers guide the shape of cells and tissues with optogenetics

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

11 June 2018 The Roche logo

Roche joins EMBL’s Corporate Partnership Programme

Roche and EMBL join forces

CONNECTIONS LAB MATTERS

2018

connectionslab-matters

8 June 2018 A stylised birds eye view of the EMBL Heidelberg Campus in green, black and white.

EMBL in six objects

A history of EMBL in six objects from the EMBL Archive

LAB MATTERS

2018

lab-matters

4 June 2018 New EMBL group leader Simone Köhler.

Welcome: Simone Köhler

Which of our genes will be passed on to our children? Simone Köhler wants to find out

PEOPLE & PERSPECTIVES

2018

people-perspectivesscience

1 June 2018 EMBL researchers and collaborators enjoy their EMBL pints.

A pint of EMBL science

EMBL and Pint of Science join forces to entertain and educate

LAB MATTERS

2018

eventslab-matters

31 May 2018

How wild species may benefit from mouse genetic data

Of mice and gorillas: using mouse data for conservation

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

30 May 2018 Montenegro is EMBL's 25th member state

Welcome to EMBL, Montenegro!

Montenegro becomes EMBL’s 25th member state

CONNECTIONS LAB MATTERS

2018

connectionslab-matters

29 May 2018 Intermediate detection in capsid formation of the lumazine synthase enzyme. CREDIT: Aleksandra Krolik / EMBL

Reconstructing 3D shapes from unmeasurable data

Scientists at EMBL Hamburg determine shapes of intermediate states in dynamic biological systems

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

28 May 2018 In this image of developing cells, fluorescent molecules reveal DNA (blue), part of the X chromosomes (red), and the Xist RNA (white). The green colour shows a region of the cells’ nuclei called the nuclear lamina. IMAGE: Mikael Attia and Edith Heard/Institut Curie

In this image of developing cells, fluorescent molecules reveal DNA (blue), part of the X chromosomes (red), and the Xist RNA (white). The green colour shows a region of the cells’ nuclei called the nuclear lamina. IMAGE: Mikael Attia and Edith Heard/Institut Curie

The scientific origins of Edith Heard

EMBL’s next Director General reflects on the questions that drive her research

PEOPLE & PERSPECTIVES

2018

people-perspectivesscience

25 May 2018 Melina Schuh has received an EMBO Gold Medal for outstanding contributions to the life sciences in Europe.

Melina Schuh receives EMBO Gold Medal

EMBL alumna Melina Schuh recognised for excellence in science

PEOPLE & PERSPECTIVES

2018

alumnipeople-perspectives

24 May 2018 Daniel Elias Martin Herranz EMBL-EBI

PhD goals: why not start a company?

EMBL-EBI PhD student launches start-up focusing on epigenetics and wellbeing

LAB MATTERS PEOPLE & PERSPECTIVES

2018

lab-matterspeople-perspectives

23 May 2018 As a cell prepares to divide, the chromosomes (shown here in pink) condense, becoming more tightly coiled and easier to observe under the microscope. The faint structure in the centre is a cell nucleus in which the chromosomes are in their usual decondensed state.

As a cell prepares to divide, the chromosomes (shown here in pink) condense, becoming more tightly coiled and easier to observe under the microscope. The faint structure in the centre is a cell nucleus in which the chromosomes are in their usual decondensed state.

Exploring genetic variation

EMBL group leader Jan Korbel reflects on his scientific origins and current research

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

14 May 2018 EMBL alumna Elisa Izaurralde.

Obituary: Elisa Izaurralde

Elisa Izaurralde, EMBL alumna, has passed away

PEOPLE & PERSPECTIVES

2018

alumnipeople-perspectives

11 May 2018 Iain Mattaj has been elected as a foreign associate of the National Academy of Sciences (NAS) of the United States of America.

Iain Mattaj elected NAS foreign associate

EMBL’s Director General has been elected to the National Academy of Sciences of the United States

EMBL ANNOUNCEMENTS LAB MATTERS

2018

embl-announcementslab-matters

10 May 2018 MRI image of a medulloblastoma

New risk factors for rare childhood cancer

Researchers identify genes that can cause brain tumours in children and other cancers later in life

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

9 May 2018 Benito-Gutiérrez searching for cephalochordates on board the dhoni boat

Ocean origins

EMBL alumna, Èlia Benito-Gutiérrez, on how her research and career evolved after searching the seas

LAB MATTERS PEOPLE & PERSPECTIVES

2018

lab-matterspeople-perspectives

8 May 2018 Mark Green retires after 20 years at EMBL.

20 years of building teams and sites

Mark Green, EMBL-EBI’s Head of Administration reflects on his time at the institute

PEOPLE & PERSPECTIVES

2018

alumnipeople-perspectives

7 May 2018

CRISPR: from clipping scissors to word processor

New platform transforms CRISPR gene editor into precision tool

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

4 May 2018 Celgene logo on white background

Celgene joins Open Targets

New partner strengthens drug discovery collaboration

CONNECTIONS LAB MATTERS

2018

connectionslab-matters

3 May 2018 C. Elegans microscopy

New insights into the origins of cancer

What worms can tell us about cancer

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

2 May 2018 Guests at the Annual Reception.

EMBL Annual Reception: focussing on young talent

On April 12, EMBL hosted 200 attendees at its Annual Reception in Heidelberg and highlighted its role as a training hub.

LAB MATTERS

2018

eventslab-matters

26 April 2018 Dividing cell colored in a heat gradient, highlighting the variation in proteins’ thermal stability within and between different cell cycle stages. IMAGE: Aleksandra Krolik / EMBL

Dividing cell colored in a heat gradient, highlighting the variation in proteins’ thermal stability within and between different cell cycle stages. IMAGE: Aleksandra Krolik / EMBL

Protein stability and solubility during cell cycle

EMBL scientists uncover large solubility and thermal stability changes of proteins during the cell cycle

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

25 April 2018 The Sharpe group at EMBL Barcelona is using GPUs to build agent-based models for morphogenesis, like this branching sequence.

The rise of GPU computing in science

Discover how EMBL scientists are using GPU computing to push biology forward

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

24 April 2018

Managing chronic pain with light

Scientists at EMBL Rome develop new method that uses light to manage neuropathic pain in mice

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

23 April 2018

International science: Sanja Damjanović

Montenegro’s Minister of Science discusses the importance of international collaboration in research

CONNECTIONS LAB MATTERS

2018

connectionslab-matters

20 April 2018

Welcome: Anna Kreshuk

New Heidelberg group leader creates tools to help biologists work faster and better

PEOPLE & PERSPECTIVES

2018

people-perspectivesscience

19 April 2018

Dog microbiome closer to humans’ than expected

Dog and human gut microbiomes have more similar genes and responses to diet than previously thought

PEOPLE & PERSPECTIVES

2018

people-perspectivesscience

18 April 2018

A serendipitous window into life’s beginnings

Markus Ralser, upcoming EMBO workshop speaker, on how metabolism brought chemistry to life

PEOPLE & PERSPECTIVES

2018

eventspeople-perspectives

9 April 2018 A 2D dataset reconstructed to show the protein's 3D quality, using the newly developed software

New software makes 3D imaging accessible

Open-source software allows standard microscopes to accurately image 3D structures

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

9 April 2018 Locations of Condensins I and II on chromosomes during cell division

Counting condensins on chromosomes

EMBL scientists count and locate chromosomal proteins during cell duplication

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

5 April 2018

PDX Finder – Free global portal for cancer models

Launch of the first free global online catalogue of PDX models

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

28 March 2018 Virginie Uhlmann on EPFL campus

Welcome: Virginie Uhlmann

New EMBL-EBI Group Leader will make sense of bioimaging data

PEOPLE & PERSPECTIVES

2018

people-perspectivesscience

26 March 2018 Multiple synapse heads send out filopodia (green) converging on one microglia (red), as seen by focused ion beam scanning electron microscopy (FIBSEM).

Multiple synapse heads send out filopodia (green) converging on one microglia (red), as seen by focused ion beam scanning electron microscopy (FIBSEM).

Captured: microglia nibbling on brain synapses

For the first time, EMBL Rome researchers have captured microglia nibbling on brain synapses on film.

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

22 March 2018

LifeTime – a visionary proposal for an EU Flagship

Following the completion of the Human Genome Project in 2001, scientists and the media described the genome as “the book of life”, holding the answers to the way genes are linked to disease. Yet, seventeen years later, we are still deciphering how cells interpret this book. Since…

CONNECTIONS LAB MATTERS

2018

connectionslab-matters

22 March 2018 Artist's representation of gene expression

New method probes gene expression by cell location

What does a cell's location tell us?

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

21 March 2018 Maria Garcia Alai at the Sample Preparation and Characterisation Facility at EMBL Hamburg. PHOTO: EMBL/Joanna Pieprzyk

Welcome: Maria Garcia Alai

The new head of facility at EMBL Hamburg will help users solve protein puzzles

PEOPLE & PERSPECTIVES

2018

people-perspectivesscience

21 March 2018 Rosa Paolicelli holds her trophy, a 3D printed microglia. Mariko Bennett and Cornelius Gross stand either side of her

First Ben Barres Prize awarded at EMBO Microglia

EMBL Group Leader creates Ben Barres Prize to support talented young neuroscientists

EMBL ANNOUNCEMENTS LAB MATTERS

2018

embl-announcementslab-matters

20 March 2018 A heatmap graph displaying high (red) or low (blue) levels of gene expressions in different cells.

From blood vessels to blood stem cells

EMBL scientists discover how blood vessel cells become blood stem cells during embryonic development

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

19 March 2018

Commonly used drugs affect our gut bacteria

One in four drugs with human targets inhibit the growth of bacteria in the human gut, and may promote antibiotic resistance, EMBL researchers report in Nature

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

19 March 2018

Molecular cuisine for gut bacteria

EMBL scientists show how to grow a wide range of gut bacteria in the lab

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

15 March 2018 Potential new way to limit antibiotic resistance spreading. IMAGE: Aleksandra Krolik / EMBL

Potential way to limit antibiotic resistance

EMBL scientists unravel the molecular basis of a major antibiotic resistance transfer mechanism

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

15 March 2018

How drugs affect the life and death of proteins

Scientists at EMBL and Cellzome develop technology to monitor the effects of drug treatments on protein degradation and synthesis

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

14 March 2018 Information (arrows) emanating out of chromatin to give rise to different cell types. IMAGE: Campbell Medical Illustration

Chromatin usage reveals developmental trajectories

EMBL scientists show how chromatin usage in individual cells reveals developmental trajectories

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

14 March 2018

DNA replication stress in cancer

Thanos Halazonetis discusses the EMBO/EMBL Symposium: DNA Replication: From Basic Biology to Disease

SCIENCE & TECHNOLOGY

2018

eventsscience-technology

13 March 2018 Exploratory Visualization Environment for Research and Technology (EVEREST) is a 3D visualisation room for the output data of the Oak Ridge National Laboratory's supercomputers.

Exploratory Visualization Environment for Research and Technology (EVEREST) is a 3D visualisation room for the output data of the Oak Ridge National Laboratory's supercomputers.

The future of Training (3)

EMBL experts outline the trends shaping scientific training in the coming years

2018

events

13 March 2018 EMBL IT support engineer Vasiliki Karyoti walking down a corridor

Being an IT support engineer: go everywhere, know everyone

For Vasiliki Karyoti, troubleshooting and problem-solving take on a greater meaning at EMBL

LAB MATTERS PEOPLE & PERSPECTIVES

2018

lab-matterspeople-perspectives

12 March 2018 Robert Prevedel talks about EMBL and microscopy at the Internationale Gesamtschule Heidelberg. PHOTO: EMBL/Hugo Neves

Science in a suitcase

School students build fluorescence microscopes designed by members of the Prevedel group and ELLS

LAB MATTERS

2018

eventslab-matters

8 March 2018 Netrin-1 bound to Draxin

Axon guidance and bundling are linked

EMBL scientists discover how two guidance cues work together when neurons project axons across the midline

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

7 March 2018 EMBL spinoff Velabs Therapeutics to help antibody discovery. IMAGE: Velabs Therapeutics

EMBL spinoff to help antibody discovery

New EMBL spinoff company Velabs Therapeutics aims to speed up discovery of therapeutic antibodies

LAB MATTERS SCIENCE & TECHNOLOGY

2018

lab-mattersscience-technology

6 March 2018

The genetic risk factors for depression

Is depression in your genes?

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

5 March 2018 Maria Leptin, EMBO Director and EMBL group leader

A chance to make scientists’ voices heard

Maria Leptin reflects on how to create a research environment that serves the needs of the community

LAB MATTERS PEOPLE & PERSPECTIVES

2018

lab-matterspeople-perspectives

5 March 2018 ERC Scientific Council members and local scientists get a chance to mingle at a reception and formal dinner at the Prinz Carl Palais in Heidelberg

ERC Scientific Council members and local scientists get a chance to mingle at a reception and formal dinner at the Prinz Carl Palais in Heidelberg

ERC Scientific Council meets in Heidelberg

EMBL and EMBO hosted the ERC's Scientific Council in Heidelberg 28 February to 2 March

CONNECTIONS

2018

connectionsevents

2 March 2018 HiGlass (http://higlass.io) is an exploratory visualization tool for genomic data developed by Nils Gehlenborg and his team that provides analysts with a flexible interface to explore genomic and epigenomic data, including genome wide interactions, across multiple scales. IMAGE: Nils Gehlenborg

HiGlass (http://higlass.io) is an exploratory visualization tool for genomic data developed by Nils Gehlenborg and his team that provides analysts with a flexible interface to explore genomic and epigenomic data, including genome wide interactions, across multiple scales. IMAGE: Nils Gehlenborg

Kendrew and Philipson Awards Winners 2018

EMBL recognises the outstanding work of alumni with the John Kendrew and Lennart Philipson Awards

EMBL ANNOUNCEMENTS

2018

alumniembl-announcements

28 February 2018

Origins at EMBL

Join us in our new editorial theme as we ask how everything began

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

28 February 2018

Insights into early cell life

New technique offers insight into early cell life

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

23 February 2018 Meet some of the Humans of EMBL

Humans of EMBL: Past lives

Discover the past lives and journeys that brought people to EMBL

LAB MATTERS PEOPLE & PERSPECTIVES

2018

lab-matterspeople-perspectives

23 February 2018 Felix Weis at the new cryo-EM service platform.

New cryo-EM service at EMBL Heidelberg

Access to state-of-the-art microscopes and outstanding expertise

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

22 February 2018 A condensin protein complex creates a loop in DNA. IMAGE: Cees Dekker Lab TU Delft/Scixel

Loops, loops and loops: how DNA gets organised

Researchers from Delft University and EMBL crack the mystery of condensin’s neat DNA loop extrusion

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

22 February 2018

Synchronised waves control embryonic patterning

EMBL scientists show that the rhythm between Wnt and Notch waves enables patterning in embryos.

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

21 February 2018 Retinoic acid signalling is crucial for the marine worm’s nervous system (green) to develop

Insights into the evolution of a signalling molecule

EMBL scientists discover how a molecule’s role changes from simple metabolite to instructive signal

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

21 February 2018 10x Genomics joined EMBL's Corporate Partnership Programme

10x Genomics joins EMBL’s Corporate Partnership Programme

Joining forces for single-cell research

CONNECTIONS LAB MATTERS

2018

connectionslab-matters

20 February 2018 Jacques Dubochet holding his Nobel medal during Nobel week. PHOTO: Alexander Mahmoud ©Nobel Media AB 2017

Jacques Dubochet donates Nobel medal to EMBL

“In testimony of my great thankfulness”

PEOPLE & PERSPECTIVES

2018

alumnipeople-perspectives

16 February 2018 New EMBL group leader Sara Cuylen-Häring will explore biophysical properties of chromosomes and other cellular assemblies.

Welcome: Sara Cuylen-Häring

New EMBL group leader explores biophysical properties of chromosomes and other cellular assemblies

PEOPLE & PERSPECTIVES

2018

people-perspectivesscience

15 February 2018 School visit on the International Day of Women and Girls in Science

Women in Science Day: school event

EMBL Barcelona organises first school activity to coincide with the International Day of Women in Science

LAB MATTERS

2018

eventslab-matters

15 February 2018 Architecture dependent turnover of the nuclear pore subunits. Top row shows the nuclear pore subunits seen from top, bottom row shows subunits of the nuclear pore cut in half.

Architecture dependent turnover of the nuclear pore subunits. Top row shows the nuclear pore subunits seen from top, bottom row shows subunits of the nuclear pore cut in half.

Life and death of proteins

EMBL scientists create a turnover catalogue of almost 10.000 proteins from primary cells

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

13 February 2018

The future of Training (2)

EMBL experts outline the trends shaping scientific training in the coming years

LAB MATTERS

2018

eventslab-matters

12 February 2018

Study identifies new diabetes genes

Network of genes linked to development of diabetes

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

12 February 2018 Charles Darwin portrait gravure - Darwin’s studies of orchids firmly established the idea that many types of flowers are pollinated by insects. PHOTO: iStock

Charles Darwin portrait gravure - Darwin’s studies of orchids firmly established the idea that many types of flowers are pollinated by insects. PHOTO: iStock

On the orchids of Darwin

How Darwin’s work revealed the intimate relationship between orchids and insects

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

9 February 2018 Arnaud Krebs, EMBL’s new group leader studies how gene expression is controlled

Welcome: Arnaud Krebs

EMBL’s new group leader studies how gene expression is controlled

PEOPLE & PERSPECTIVES

2018

people-perspectivesscience

8 February 2018 Optogenetics has successfully been used in a diverse range of organisms.

EMBL’s first wetlab e-learning courses go live

EMBL’s training programme launches its first e-learning courses: introductions to optogenetics and CLEM

EMBL ANNOUNCEMENTS

2018

embl-announcementsevents

31 January 2018

Slovakia becomes EMBL member state

EMBL welcomes Slovakia as its 24th member state

CONNECTIONS LAB MATTERS

2018

connectionslab-matters

31 January 2018

Using mini brains to understand big brains

What opportunities can organoids bring to further the understanding of the human brain?

SCIENCE & TECHNOLOGY

2018

eventsscience-technology

30 January 2018

Former fellows of EMBL’s International PhD Programme reunited at EMBL in Heidelberg on 23 September, two decades after finishing their PhDs. They toured the lab and reminisced about past times. From left to right: Marko Hyvönen (now at the University of Cambridge), Anders Isaksson (Uppsala University), Isabel Palacios (University of Cambridge), Christian Engel (Sanofi-Aventis), Gaetano Vitale (University of Udine), Morten Grøtli (Gothenburg University), Elena Baraldi (University of Bologna), and Medard Hein Tseong Ng (University of Virginia).

EMBL PhD students reunite 20 years on

Among refurbished labs, alumni relive memories and find traces of their time at EMBL

PEOPLE & PERSPECTIVES

2018

alumnipeople-perspectives

30 January 2018 Enhancer activity (green) and promoter activity (purple) in the same regulatory element. IMAGE: EMBL / Eileen Furlong

Multipurpose enhancers and promoters in embryonic development

EMBL scientists show that some promoters can act as enhancers and vice versa

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

29 January 2018 $General view of the ID23-2 sample environment showing the MD3-Up diffractometer and FlexHCD sample changer. PHOTO: EMBL/J. Sinoir$

Beamline ID23-2 tools up for ESRF upgrade

EMBL instrumentation teams adapting tech to run biological experiments on the synchrotron after its upgrade

LAB MATTERS SCIENCE & TECHNOLOGY

2018

lab-mattersscience-technology

22 January 2018 Sample of DNA with digital information stored in it

Belgian PhD student decodes DNA and wins a Bitcoin

Nick Goldman of EMBL-EBI issued a challenge in 2015. In 2018, a winner emerged just in time.

SCIENCE & TECHNOLOGY

2018

sciencescience-technology

17 January 2018 With help from an external transcription factor (lavender, peach, and green), Pol III (grey) and its built-in transcription factor (yellow), create a cage around a cell’s DNA (plum). IMAGE: EMBL/Matthias Vorländer