October 22, 2025 00:002025ConferenceEMBL Heidelberg, Virtual

Description OverviewSpeakersProgrammeIndustry workshopsEMBO trainingPractical informationSponsorsAboutMedia kit Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Symposium overview The ability to grow tissues from stem cells in 3D culture to generate so called organoids has revolutionised the study of tissue biology especially human biology This exciting technology has great potential for drug discovery and regenerative medicine Because organoids model a variety of tissues with remarkably high fidelity they allow for new discoveries in human development homeostasis regeneration and disease This symposium will bring together the leading researchers in this field representing the premier conference for this research community and providing a much anticipated program that demonstrates how this field is truly pushing the boundaries for our understanding of tissue biology The fifth edition of this established meeting will again bring together researchers from different fields to enhance our understanding of how organoids can be formed and maintained and their biomedical applications from how they can be exploited to study disease to eventually use them to regenerate and replace human tissues An aim for the 2025 edition of the symposium is the incorporation of more complementary technologies such as multiomics engineered embryo models and bioengineering as well as increased representation of the topic of cancer Session topics Concepts from development Building organoid complexity I Building organoid complexity II Organoids in regenerative medicine Organoids in disease modeling Organoids and engineering What past participants say about the Symposium The EMBO EMBL Symposium Organoids Modelling organ development and disease in 3D culture was a fantastic opportunity to network with researchers from around the world to learn about new techniques and the latest exciting research Especially the top class line up of invited and keynote speakers left an impression I am looking forward to the program of the next symposium Rhena Klar University Medical Center Freiburg German Cancer Consortium DKTK Partner Site Freiburg Germany At the EESOrgan Symposium it was all about diving deep into organoid breakthroughs sharing insights and getting inspired by leading voices in the field Between the thought provoking talks interactive poster sessions and that memorable party this event is a must for everyone passionate about organoid research Branka Radic Sarikas St Anna Children s Cancer Research Institute and Medical University of Vienna Speakers Keynote speakers Paola Arlotta Harvard University USA Matthias L tolf Roche Institute of Human Biology Switzerland Speakers Eduard Batlle IRB Barcelona Spain Miki Ebisuya Matsuda TU Dresden Germany Calvin Kuo Stanford University USA Bon Kyoung Koo Center for Genome Engineering Republic of Korea Joo Hyeon Lee Memorial Sloan Kettering Cancer Center USA Prisca Liberali Friedrich Miescher Institute for Biomedical Research Switzerland Guo li Ming University of Pennsylvania USA Jos Polo University of Adelaide Australia Giorgia Quadrato University of Southern California USA Nicolas Rivron Institute of Molecular Biotechnology Austrian Academy of Sciences Austria Toshiro Sato Keio University School of Medicine Japan Minoru Takasato RIKEN Japan Margherita Yayoi Turco Friedrich Miescher Institute for Biomedical Research Switzerland Jesse Veenvliet Max Planck Institute of Molecular Cell Biology and Genetics Germany Vincenzo Corbo University of Verona Italy Founding steering group members Hans Clevers Utrecht University The Netherlands Juergen Knoblich Institute of Molecular Biotechnology Austria Scientific Organisers Meritxell Huch Max Planck Institute of Molecular Cell Biology and Genetics Germany Karl R Koehler Boston Children s Hospital and Harvard Medical School USA Madeline Lancaster MRC Laboratory of Molecular Biology UK Esther Schnapp EMBO Press Germany Conference Organiser Adela Graf EMBL Heidelberg Germany Aline Schnieder EMBL Heidelberg Germany Programme Are you on social media Post using EESOrgan and don t forget to tag EMBLEvents Please note that the programme is subject to change Some speakers may need to join virtually to give their talk For registered participants recorded talks will be accessible on demand for 4 weeks after the end of the event unless indicated otherwise Please find the poster listing here Please find the symposium bus schedule here Day 1 Wednesday 22 October 2025 Time Europe Berlin Speaker11 30 13 30Registration and light refreshmentsRegistration is kindly sponsored by 10x Genomics12 00 13 00Concurrent Industry workshops13 30 13 45Opening remarks 13 45 17 00Session 1 Concepts from development Chairs Esther Schnapp EMBO Germany Madeline Lancaster MRC Laboratory of Molecular Biology UK13 45 14 30Keynote lecture 1 Passage of time in brain organoids the journey to understand human brain developmentPaola Arlotta Harvard University USA14 30 14 45Reversible epiblast regionalisation determines differentiation potential of PSCsMagdalena Sutcliffe MRC Laboratory of Molecular Biology UK14 45 15 10Understanding human reprogramming a journey from epiblast to trophoblast and into iBlastoidsJos Polo University of Adelaide Australia15 10 15 25Post gastrulation amnioids as a stem cell derived model of human extra embryonic developmentBorzo Gharibi The Francis Crick Institute UK15 25 15 55Coffee Break Meet the speakers ExhibitionMeet the speakers with Paola Arlotta and Jos Polo15 55 16 20Genetic determinants of the evolution of timing of human blastocyst implantationNicolas Rivron Institute of Molecular Biotechnology Austrian Academy of Sciences Austria16 20 16 35A blastocyst derived in vitro model of the human chorionLuca Schwarz MRC Laboratory of Molecular Biology UK16 35 17 00Phenotypic landscapes of human intestinal regeneration in organoidsPrisca Liberali Friedrich Miescher Institute for Biomedical Research SwitzerlandNot available on demand17 00 18 00Poster sneak peek18 00 19 30Dinner in Canteen19 30 21 00After dinner drinks in ATC foyer Day 2 Thursday 23 October 2025 Time Europe Berlin Speaker09 00 12 00Session 2 Building organoid complexity IChairs Karl R Koehler Boston Children s Hospital USA Guo li Ming University of Pennsylvania USA09 00 09 25Creating to understand leveraging embryo models to discover principles of developmentJesse Veenvliet Max Planck Institute of Molecular Cell Biology and Genetics GermanyNot available on demand09 25 09 40Using pluripotent stem cell derived pancreatic organoids to model human pancreas organogenesisJonathan Brassard Cincinnati Children s Hospital Medical Center USANot available on demand09 40 09 55Sensing skin in a dish building human organoids with multimodal sensory neuronsJiyoon Lee Boston Children s Hospital Harvard Medical School USANot available on demand09 55 10 25Coffee Break Meet the speakers ExhibitionMeet the speakers with Nicolas Rivron and Jesse Veenvliet10 25 10 50Generation of urinary tract organoids from human pluripotent stem cellsMinoru Takasato RIKEN BDR Japan10 50 11 05The mechanics of morphogenesis biomechanical drivers of 3D shape emergence in posterior trunk organoidsRyan Harrison University of Warwick The Francis Crick Institute UK11 05 11 30Upgrading the physiological relevance of human cerebellar organoidsGiorgia Quadrato University of Southern California USANot available on demand11 30 11 45Guided maturation of human neuromuscular organoids through electrical stimulationChrysanthi Maria Moysidou Max Delbr ck Center for Molecular Medicine GermanyNot available on demand11 45 12 00Human periportal liver assembloids as a novel in vitro platform to model liver pathophysiologyYuan Lei Max Planck Institute of Molecular Cell Biology and Genetics Germany12 00 13 3012 30 13 30Lunch ExhibitionMeet the editors13 30 18 00Session 3 Building organoid complexity IIChairs Toshiro Sato Keio University School of Medicine Japan Jesse Veenvliet Max Planck Institute of Molecular Cell Biology and Genetics Germany13 30 13 55Modeling and reprogramming pro fibrotic cell states in pulmonary fibrosisJoo Hyeon Lee Memorial Sloan Kettering Cancer Center USANot available on demand13 55 14 10Modelling vascular malformations using patient derived iPSC vascularized organoids and endothelial progenitorsMaximiliano Arce Uppsala University Sweden14 10 14 25Title tbcMelissa Little Murdoch Children s Research Institute USANot available on demand14 25 14 50Modeling epithelial immune interactions in human organoidsCalvin Kuo Stanford University USANot available on demand14 50 15 20Coffee Break Meet the speakers ExhibitionMeet the speakers with Minoru Takasato and Joo Hyeon Lee15 20 15 50Flash talk session 1 43 Albertini Silvia 44 Alonso Alvarez Pedro 55 Belharazem Djeda 92 Dokuzluoglu Zeynep 96 Dubrovska Hanna 117 Grommisch David 119 Gupta Pallavi 173 Meteling Marieke 187 Niksic Armin 227 Tornabene Patrizia 247 Yang Qiutan15 50 18 00Poster Session 1 odd numbers Please find the poster listing here18 00Free evening Optional guided tour for participants limited places available Day 3 Friday 24 October 2025 Time Europe Berlin Speaker09 00 11 45Session 4 Organoids in regenerative medicineChairs Meritxell Huch Max Planck Institute of Molecular Cell Biology and Genetics Germany Jose Polo University of Adelaide Australia09 00 09 25Growing organoids in 2D and 3D using Yersinia s Invasin as an alternative to MatrigelHans Clevers F Hoffmann La Roche Ltd Hubrecht Institute The Netherlands09 25 09 40Conserved signals control self organization and symmetry breaking of murine bi layered epithelia during development and regenerationRobin Journot Institut Curie France09 40 09 55Building and breaking the blood CSF barrier human choroid plexus organoids reveal injury repair dynamicsLaura Pellegrini King s College London UKNot available on demand09 55 10 25Coffee Break Meet the speaker ExhibitionMeet the speaker with Hans Clevers10 25 10 50Maternal cues shaping regeneration and differentiation of the human placentaMargherita Yayoi Turco Friedrich Miescher Institute for Biomedical Research SwitzerlandNot available on demand10 50 11 05Bioengineered human colorectal cancer assembloids for image based analysis of individualized tumor microenvironmentsMaria Correia Melo Georg Speyer Haus Institute for Tumor Biology and Experimental Therapy GermanyNot available on demand11 05 11 30Modeling subcortical band heterotopia using human brain organoidsGuo li Ming University of Pennsylvania USANot available on demand11 30 11 45Mapping and targeting patient specific CAR T cell barriers using a colorectal cancer organoid platformHenner Farin Georg Speyer Haus Institute for Tumor Biology and Experimental Therapy Germany11 45 13 15Lunch 12 00 13 00European Research Council SessionMariam Benjdia European Research Council BelgiumNot available on demand13 15 18 30Session 5 Organoids in disease modellingChairs Margherita Turco Friedrich Miescher Institute for Biomedical Research Switzerland Bon Kyoung Koo Center for Genome Engineering Republic of Korea13 15 13 40Cerebral organoids growing human brain tissue from stem cells to study development and diseaseJuergen Knoblich Institute of Molecular Biotechnology Austria13 40 13 55Spatio cellular carcinogenic dynamics in 3D mammary organoids decoding stem cell fate and tumor susceptibilityRuolan Tang Westlake University China13 55 14 10Unbiased niche labelling identifies Kupffer cells as the architects of metastatic niche formation in colorectal cancerBonis Evangelos ETH Zurich Switzerland14 10 14 40Coffee Break Meet the speakers ExhibitionMeet the speaker with Margherita Yayoi Turco Guo li Ming and Juergen Knoblich14 40 15 05Plasticity and therapy resistance in metastatic colorectal cancerEduard Batlle ICREA Cancer Science Program Institute for Research in Biomedicine IRB Barcelona The Barcelona Institute of Science and Technology BIST SpainNot available on demand15 05 15 20Multi omics profiling of orthoflavivirus induced neurodevelopmental alterations in human neural organoidsAmal Fahmi University of Bern Switzerland15 20 15 45Modeling human tissue homeostasis regeneration and disease for endoderm derived tissue systemToshiro Sato Keio University School of Medicine JapanNot available on demand15 45 16 00Modelling Stargardt disease using three dimentional retinal organoidsCl ment Morival Nantes University France16 00 16 30Flash talk session 2 114 Jarde Thierry 116 Groen Eline 132 Jeong Youngtae 148 Kuodyte Karolina 152 Lahmann Ines 156 Lee Daniel Ming Kang 164 Lucidi Benedetta 174 Micati Diana 192 Ratcliffe Colin 196 Rostami Sabra 206 Giroux Veronique 246 Wolff Lisa16 30 18 30Poster Session 2 even numbers Please find the poster listing here18 30 20 30Conference dinner in the canteen20 30 00 00Party with band Day 4 Saturday 25 October 2025 Time Europe Berlin Speaker09 00 13 00Session 6 Organoids and engineeringChairs Karl R Koehler Boston Children s Hospital USA Madeline Lancaster MRC Laboratory of Molecular Biology UK09 00 09 25Organoids Zoo a new platform for animal scienceBon Kyoung Koo Center for Genome Engineering Republic of Korea09 25 09 40Functional innervated gut tissue generation via a confined culture scaffold systemHolly M Poling University of Cincinnati USA09 40 10 05Modelling EcDNA dynamics in pancreatic cancer using organoidsVincenzo Corbo University of Verona Italy10 05 10 20Monitoring macaque brain organoid maturation using magnetic resonance imaging and spectroscopyMemhave Tor Rasmus German Primate Center Germany10 20 10 50Coffee Break Meet the speakers ExhibitionMeet the speaker with Eduard Batlle Toshiro Sato Bon Kyoung Koo Vincenzo Corbo10 50 11 15Species specific basal surface fluidization shapes early forebrain developmentMiki Ebisuya Matsuda TU Dresden GermanyNot available on demand11 15 11 30High throughput crispr and drug screening platform to harness the translatability of human patient derived organoids by enhancing target and drug discoveryLuigi Aloia AstraZeneca UK11 30 12 15Keynote lecture 2 Engineering organoids Matthias L tolf Roche Institute of Human Biology SwitzerlandNot available on demand12 15 12 30Closing remarks and poster prize announcements12 30 13 00Packed lunch and departure12 45Bus shuttle to Frankfurt am Main airport13 00Bus shuttle downtown all stops Industry workshops For on site participants only The following industry workshops will be hosted by the sponsors of EMBO EMBL Symposium Organoids modelling organ development and disease in 3D to the start of the event on Wednesday 22 October 2025 12 00 13 00 Adding a new dimension to in vitro research single cell and spatial solutions for organoids by Clara Hayn University of Bonn and Sara Milosevic 10x Genomics Main Auditorium Imaging and Analysis of 3D cell cultures using ZEISS microscope systems and Arivis by Dr Volker D ring Carl Zeiss Microscopy Room Helix A01 Modeling Alzheimer s Disease with Brain Organoids From Molecular Mechanisms to Functional Phenotyping by Dr Dasa Bohaciakova MaxWell Biosystems Room Helix B01 Streamlined 3D Organoid Imaging with the Eclipse Ji and AX Confocal Platform by Subash Chinnaraj Frank van den Boom Nikon Room FlexLab A Advancing Organoid Models Introducing New Capabilities for Intestinal Pulmonary and Hepatic Research by Salvatore Simmini STEMCELL Technologies Room FlexLab B In order to read the abstract of each workshop please click on the corresponding links above Participation in this workshop is free of charge for registered on site conference attendees The available place is limited first come first served All registered conference attendees will receive an email with a registration link shortly All pre conference workshops will take place simultaneously therefore please choose the one you would be interested in the most EMBO training EMBO training session How to write a scientific paper Please note that this training requires separate registration via annika diederich embo org Overview This training module introduces the fundamental elements of publishing scientific research focusing on the structure and content of a manuscript how to assemble effective figures and how to write impactful titles and abstracts Led by an experienced EMBO Press scientific editor participants will explore the strategic planning for publication including determining authorship organising data and selecting the most appropriate journal for submission The session will run for 4 hours on the first morning of the symposium and will provide an engaging and interactive learning environment Date Wednesday 22 October 2025 Time 8 30 12 30 Europe Berlin It will include hands on exercises group work and lively discussions to help participants develop a practical understanding of how to write a successful scientific paper Audience This training session is designed for a maximum of 20 PhD students and postdocs who want to improve their scientific writing and publishing skills Learning outcomes At the end of the module participants will Understand the purpose and the structure of each section of a scientific paper title and abstract introduction results materials and methods discussion references and data availability Gain practical experience in assembling figures and writing titles and abstracts Receive guidance from instructors and peer feedback to refine the critical components of a successful scientific manuscript Registration For more information and to register please contact annika diederich embo org Registration deadline 15 October 2025 The training session is limited to 20 participants who will be selected on a first come first served basis Selected participants must commit to attending the entire module Practical information Registration fees and abstract submission Registration On site registration fees include admission conference materials meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Virtual registration fees include access to all of the talks livestreamed and on demand and facility to submit questions On site Academia 725On site PhD Student 625On site Industry 925On site EMBL staff press 300Virtual Academia 225Virtual PhD Student 175Virtual Industry 275 Editors from scientific journals are allowed to attend at a reduced rate but asked to contribute to the conference in return by taking part in meet the editors sessions or other planned activities within the programme A letter to support your visa application will be issued on request once payment of the registration fee is confirmed We recommend that you book your visa appointment as soon as possible to avoid any delay with your visa application Accredited journalists may be eligible to register for complimentary press registration Registrants may be required to provide accreditation or equivalent proof of press membership after registration Please contact Aline Schnieder for more information Please note that we do not offer complimentary registrations for editors of scientific journals Confirmation and payment Registration will be on a first come first served basis Your place can only be confirmed after payment of the registration fee If you are added to our waiting list please consider taking advantage of our offerings to participate virtually On site participants Types of payments accepted are international bank transfers and credit card payments Virtual participants We are only able to accept card payments In exceptional cases we can accept bank transfers Please contact events embl de for details Abstract submission Only participants registering to attend the on site event are eligible to submit an abstract Abstracts will not be accepted from virtual participants After registration you can submit your abstract via a separate link that will be provided in the email confirmation Alternatively you can access the link on the confirmation page directly after registering The same login credentials are used for both processes Please note Abstract body The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised Title The title should not exceed 20 words Only the first word of the title should start with a capital letter and the rest should be lowercase Authors and affiliations Please fill in the author s details as requested in the online form The compulsory fields are First Name Last Name Organisation Name Affiliation or Company Country and Email Kindly mark only one author in the role of First Author and please don t forget to indicate who will be the Presenter Please enter your co authors correctly via the system by adding accounts together with their organisation institute Do not copy paste them into the body of the abstract text as they will not be indexed in the abstract book Presentation types When submitting your abstract you can apply for an oral or poster presentation A selection process will take place with the results announced 2 3 weeks after the abstract submission deadline For detailed instructions on how to submit a conference abstract follow the instructions provided in this video Please check our FAQs pages for further information on how to submit an abstract Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of registration fee waivers travel grants and childcare grants Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course or conference Travel grant The travel grant will cover the cost of travel to an on site event airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from within Europe up to 1000 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from outside Europe up to 500 for any participant travelling to an EMBO Workshop up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Workshop up to 700 for any participant working in Croatia Czech Republic Estonia Greece Hungary Italy Lithuania Luxembourg Poland Slovenia and Turkey travelling to an EMBO Workshop Registration fees are only covered for EMBO Workshops The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant There is the possibility to apply for a childcare grant to offset child care costs incurred by participants speakers and organisers when attending a conference Eligible costs include but are not limited to fees for a baby sitter or child care facility and travel costs for a caregiver Please note that priority will be given to early stage researchers In order to apply for this grant you must be registered by the abstract submission deadline There is a limited amount of funding available for the childcare grants and funds will be distributed amongst eligible applicants Application On site participants You may apply for financial assistance when submitting your abstract In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Virtual participants If you are attending virtually you can apply for financial assistance in the submission portal by the abstract deadline Read the instructions on how to apply for financial assistance Only submissions for financial assistance will be accepted Presentation abstracts cannot be submitted here and will be declined In your application you will be asked to summarise your current work answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Selection The scientific organisers will select the recipients of all financial assistance during the abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection for registration fee waivers and travel grants is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Childcare grants will be allocated in the same timeframe 6 8 weeks before the event start date Please note that priority will be given to early stage researchers Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details View our list of external funding opportunities and information on attending a conference as an event reporter For further information about financial assistance please refer to the FAQ page Accommodation and travel Accommodation is not included in the conference registration fee As further changes in our events are possible you should book flights trains and hotels with flexible options and favourable cancellation conditions The hotels below have rooms on hold for participants until Saturday 20 September 2025 in some cases at special rates Please email the hotel directly quoting the booking code EES25 10 to confirm the exact price of the room Hotel AnlageHotel ibis HeidelbergPremier Inn Heidelberg CityHotel Bayrischer Hof ISG Hotel Staycity Aparthotel HeidelbergB B HotelLeonardo Hotel Heidelberg City CentreHotel Vier Jahreszeiten HeidelbergExzellenz HotelMeininger HeidelbergHilton HeidelbergHotel Monpti Please note that as of 1 October 2025 Heidelberg City Council is introducing an overnight stay tax for tourists visiting Heidelberg including work related trips The cost will be 3 50 EUR per night for the first five nights of a consecutive stay and will be added to the hotel s nightly rate Please contact the individual hotel directly if you have any questions Travel information For travel information please see here EMBL Events collaborates with Deutsche Bahn to offer discounted train travel within Germany To take advantage of this offer please contact us at events embl de and we will share the discount link with you Please note that you may need to provide proof of your event attendance when purchasing the ticket and or during your travel Conference shuttle buses Conference shuttle buses are free of charge for participants and depart from designated bus stops near the hotels to EMBL and back mornings and evenings Please view the conference shuttle bus timetable here The bus stops for this conference are Hotel Staycity Speyerer Str 7 Kurf rsten Anlage Opposite Main Train Station Hotel Premier Kurf rsten Anlage 23 Leonardo Hotel Heidelberg City Center Bergheimer Str 63 Neckarmuenzplatz Heidelberg Tourist Information Peterskirche Bus stop ISG Hotel Im Eichwald 19 View Conference shuttle bus stops and hotels in a larger map Please note that not every bus stop will be used for every event Further details Address EMBL Meyerhofstra e 1 69117 Heidelberg Germany For more information about accommodation and travel please refer to the FAQ page Onsite information Catering All meals and coffee breaks are included in the registration fee Our catering staff will prepare a wide variety of vegetarian meals meat and fish dishes soups pasta fresh fruit and vegetables as well as a variety of desserts Please wear your badge at all times when serving yourself No food or drinks are allowed in the auditorium Charging lockers There are lockers available next to the stairs leading down into the Auditorium You will find some of those equipped with sockets to charge your smartphone tablet etc Electricity and charging station In most places the electricity is 220 volts AC 50 cycles An adaptor and a plug that fits the German socket may be needed for your appliances laptop i e American Japanese etc A USB charging station for electronic devices is available at the registration desk EMBL merchandise If you are interested in purchasing EMBL merchandise products presented in the glass display in the registration area please email the EMBL shop to place an order or get in contact with your Course Organiser Kindly note the EMBL shop is only open upon request and all purchases must be made in cash Euros only Health and safety notes Please read EMBL s COVID 19 safety policy for on site events Do not smoke in any EMBL building Eating and drinking is prohibited in the Auditorium and all laboratories Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required The first aid room is located next to the ATC Registration Desk room 10 205 Dial the Emergency number 222 from any EMBL internal phone only Where is the accident What happened How many injured Emergency number 06221 387 7821 from mobile phones Please report all accidents to the conference officer at the registration desk In case of fire Press the nearest fire alarm button or the Emergency number 222 from any internal phone A loud fire alarm will go off if an evacuation is required On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting points Do not use the lifts Beyond first aid Please remember to bring your own medication if needed to the conference Note that the next pharmacy is a 4 minute drive from the EMBL but for many medications you will be required to see a doctor to get a prescription Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg In any case the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary Internet Wi Fi is available on campus using the EMBL Events network and the event specific password which will be provided on site The eduroam network secure worldwide roaming access service developed for the international research and education community is also available Lost and found Lost and Found items are kept at the registration desk until the end of the conference Luggage There are lockers available on site to store your luggage which require a 2 EURO coin to operate There is another luggage room on level E0 which is free to use but remains unlocked during the conference Nursing room There is a nursing room available in the ATC Rooftop Lounge on level A29 Photography During the conference an EMBL Photographer may be taking photos If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Printing We can help to print your boarding pass train ticket Please send it to events embl de and collect your print outs at the registration desk Room for prayer yoga and meditation There is a room for prayer meditation and yoga located on level E0 behind the Auditorium Please be respectful of others using the room Sightseeing A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing Travel to and from the venue During the event we provide conference shuttle buses to and from EMBL In addition there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time Information on the conference shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page Useful German expressions HelloHalloGoodbyeAuf Wiedersehen formal Tsch ss informal Good morningGuten MorgenGood afternoonGuten TagGood eveningGuten AbendGood nightGute NachtI m sorryEs tut mir leidExcuse me Entschuldigen Sie How are you Wie gehts I m fine thanks And you Mir geht es gut danke Und dir Ihnen What is your nameWie hei en Sie formal Wie hei t du informal My name is Ich hei e Do you speak English Sprechen Sie Englisch I don t understandIch verstehe nichtPlease speak more slowlyK nnen Sie bitte langsamer sprechenThank youDankesch nWhere is the toilet Wo ist die Toilette Please call me a taxiBitte rufen Sie mir ein TaxiHow do I get to Wie komme ich zum zur A beer two beers pleaseEin Bier zwei Bier bitteA glass of red white wine pleaseEin Glas Rot Wei wein bitteThe menu pleaseDie Speisekarte bitteIs there a local speciality Gibt es eine Spezialit t aus dieser Gegend I m vegetarianIch bin VegetarierIt was deliciousEs war hervorragendThe bill pleaseDie Rechnung bitteI have a headacheIch habe KopfschmerzenI have a sore throatIch habe HalsschmerzenMy stomach hurtsIch habe MagenschmerzenI m allergic toIch bin allergisch gegenI need a doctor who speaks English Ich brauche einen Arzt der Englisch spricht Virtual participation What s included Access to all the livestreamed talks Video library of the recorded talks during the event and for 4 weeks afterwards Please note at the request of individual speakers some talks are not recorded Facility to submit questions Please note that only on site participants are able to submit abstracts and participate in the poster sessions Event platform We are using an event platform for this conference More information about the platform will be shared ahead of the conference Guidelines Do not broadcast the conference to unregistered participants You are encouraged to tweet and post about the event Tweet unless the speaker specifically says otherwise but be mindful of unpublished data Please do not capture transmit or redistribute data presented at the meeting Additional information can be found in our Code of Conduct Health and well being It is important to stay healthy and move around especially when you are attending an event virtually We have put together a few coffee break stretches and yoga videos in the conference platform for you to enjoy during the event How to ask questions Please use the Q A function in the event platform If you have any other questions you can go to the Help Desk in the event platform Click on more on the top menu and click Help Desk Time zone The programme is planned based on the Europe Berlin time zone unless otherwise stated Please take your time zone into consideration when planning your attendance Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for participants page Sponsors Gold sponsor Silver sponsor Bronze sponsor Event sponsor 3Brain Agilent Technologies BioMex Bruker FaCellitate Formulatrix MedChemExpress ORF Genetics Sino Biological Europe Union Biometrica VectorBuilder World Precision Instruments Event supporters Media partners Advanced Biology a Wiley journal Advanced Genetics a Wiley journal BioEssays a Wiley journal Cancer Drug Resistance an OAE Publishing Inc journal ChemBioChem a Wiley journal Development The Company of Biologists journal Disease Models Mechanisms The Company of Biologists journal FEBS Letters a FEBS Press journal International Union of Biochemistry and Molecular Biology Medinformatics a Bon View Publishing journal Molecular Medicine an EMBO Press journal Open Biology a Royal Society journal PLOS Biology a PLOS journal Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de About EMBO EMBL Symposia promote scientific communication and collaboration in the European research area They provide scientists with a platform to discuss and exchange ideas on forward looking topics and new developments in the life sciences Topics emphasise upcoming developments and the interdisciplinary nature of related fields Jointly funded and organised by EMBO and EMBL and complementary to their respective courses workshops and conference programmes the symposia promote scientific communication and collaboration All symposia are held in the EMBL Advanced Training Centre ATC in Heidelberg Germany or virtually Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9 Leaderboard 728 90...

Meritxell Huch, Karl R. Koehler, Madeline Lancaster, Esther Schnapp

EMBO | EMBL Symposium

EMBL Heidelberg, Virtual

Edit

October 08, 2025 14:302025WebinarVirtual

Description The accessory genome the set of genes variably present across members of a bacterial species plays a central role in shaping microbial diversity and adaptation Instead of a random collection of mobile elements evidence has shown that the accessory genome is structured by selective forces particularly negative frequency dependent selection and underpins the long term stability of multi strain bacterial populations Accessory loci are implicated in host interactions inter bacterial competition and responses to clinical interventions such as vaccination and antibiotic consumption making them a cradle of adaptive potential In this webinar we will explore how accessory genomes evolve why their composition remains stable despite turnover of lineages and how this evolutionary perspective allows us to better understand pathogen persistence and predict responses to selective pressures...

Virtual

8 October - 11 October 2025

Seeing is believing: imaging the molecular processes of life

Edit

October 08, 2025 00:002025ConferenceEMBL Heidelberg, Virtual

Description OverviewSpeakersProgrammeIndustry workshopsEMBO trainingPractical informationSponsorsMedia kitAbout Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Conference overview The molecular processes of life are naturally dynamic in space and time from the atomic to the organismal level The rapid development of imaging methods across the full scale of biological organisation is revolutionising our ability to visualise the inner workings of macromolecular complexes organelles cells tissues organs and whole organisms Being able to see biological processes unfold in real time allows us to understand the mechanisms of life as well as disease The symposium will bring together the leading developers of imaging methods with cutting edge applications that illustrate how imaging can answer biological questions We will emphasize methods that can capture the dynamics of life spanning the whole range from molecular resolution to imaging of whole organisms From its beginning in 2011 Seeing is believing has embraced novel imaging technologies that open new windows for biological discovery including single molecule and super resolution light sheet and correlative light electron microscopy The symposium provides many opportunities for presentations discussions and interactions between students postdocs junior and senior investigators Session topics Imaging structure and function of molecules in situ Dynamic super resolution microscopy Tissue and intravital imaging Probes and optical pertubation tools AI image data and modelling New approaches and applications of imaging technologies What past participants say about the Symposium What a well organized outstanding conference full of great scientific and technicalcontributions in the form of talks posters and industry exhibitions from a variety of fields It was a perfect opportunity to connect with other scientists industry representatives and journal editors and I very much appreciated the possibility to present a talk also as a younger researcher Vera M Kissling Empa Switzerland The conference is amazing and well organized with plenty of time to network during the coffee breaks and social activities while you learn something new The talks were engaging and inspiring Fernanda Garcia Fossa University of Campinas Brazil Speakers Speakers Adam Cohen Harvard University USA Florian Jug Human Technopole Italy Ralf Jungmann Max Planck Institute for Biochemistry Germany Lukas Kapitein University of Utrecht The Netherlands Wanda Kukulski University of Bern Switzerland Dong Li Tsinghua University China Alan Lowe Chan Zuckerberg Initiative USA Hideharu Mikami Hokkaido University Japan Alexandra Pacureanu ESRF European Synchrotron Radiation Facility France Gaia Pigino Human Technopole Italy Melina Schuh Max Planck Institute for Multidisciplinary Sciences Germany Ilaria Testa SciLifeLab Sweden Carolina Wahlby University of Uppsala Sweden Lihong Wang California Institute of Technology USA Scientific organisers Jan Ellenberg SciLifeLab Sweden EMBL Heidelberg Germany Jennifer Lippincott Schwartz HHMI Janelia Research Campus USA Satyajit Mayor Warwick Medical School UK Atsushi Miyawaki RIKEN Center for Brain Science Japan Conference organisers Stephanie Alexander Research Service Coordinator EMBL Heidelberg Germany Iva Gavran Course and Conference Officer EMBL Heidelberg Germany Programme Are you on social media Post using EESImaging and don t forget to tag EMBLEvents Please note that the programme is subject to change Some speakers may need to join virtually to give their talk For registered participants recorded talks will be accessible on demand for 4 weeks after the end of the event unless indicated otherwise Please see poster numbers here Please see the conference shuttle schedule here Day 1 Wednesday 8 October 2025 Time Europe Berlin Speaker11 00 13 00Registration and light refreshmentskindly sponsored by Thermo Fisher Scientific11 30 12 30Concurrent Industry Workshops by Bruker Carl Zeiss Microscopy Evident Leica Microsystems Nikon Tomocube13 00 13 15Opening remarks13 15 17 20Session 1 Tissue and intravital imagingChair Lihong Wang California Institute of Technology USA13 15 13 35Invited talk Long distance calcium signaling in neuronsJennifer Lippincott Schwarz HHMI Janelia Research Campus USA13 35 13 55Intravital imaging with targeted sensors reveals heterogeneity in lysosomal function along the kidney proximal tubuleMonika Kaminska Institute of Anatomy University of Zurich Switzerland13 55 14 15Invited talk Mapping brain dynamics in live animalsAdam Cohen Harvard University USANot available on demand14 15 14 35Long term three photon imaging of neural stem cell dynamics in the intact mouse brainYusaku Hontani University of Zurich Switzerland14 35 14 55Whole embryo spatiotemporal transcriptomics at subcellular resolutionYinan Wan University of Basel Switzerland14 55 15 40Coffee Break ExhibitionMeet the speakers with Jennifer Lippincott Schwarz and Adam Cohen15 40 16 00Invited talk Photoacoustic light speed and quantum imagingLihong Wang California Institute of Technology USA16 00 16 20Improvement of histopathological diagnostics and deep tissue phenotyping using non destructive 3D histopathology and nanobody technologyRene H gerling Charit Universit tsmedizin Berlin Germany16 20 16 40Quantifying morphodynamic behavior patterns of tissue resident macrophages in situEric Greto Erlangen Klinikum Germany16 40 17 00Dynamic and nanoscale architecture of T cells and immune synapsesBenita Wolf Lausanne University Hospital University of Lausanne Switzerland17 00 17 20Invited talk X ray nanotomography for scalable 3D imaging of preserved tissues at subcellular resolutionAlexandra Pacureanu The European Synchrotron France17 20 18 30Networking drinks18 30 20 00Conference dinner20 00 22 00Poster sneak peek and networking drinks Day 2 Thursday 9 October 2025 Time Europe Berlin Speaker09 00 12 05Session 2 Dynamic super resolution microscopyChair Ilaria Testa KTH SciLifeLab Sweden09 00 09 20Multi dimensional high spatiotemporal resolution imaging from fixed to live from 2D to 3D and beyondDong Li Tsinghua University China09 20 09 40Quantitative multicolor single particle tracking an ERAD case studyTim Abel University of California San Diego USA09 40 10 00Invited talk Dynamic imaging at the nanoscale with smart microscopy Ilaria Testa KTH SciLifeLab Sweden10 00 10 45Coffee Break ExhibitionMeet the speakers with Lihong Wang Alexandra Pacureanu Dong Li and Ilaria Testa10 45 11 05Pearling drives mitochondrial DNA nucleoid distributionJuan Cruz Landoni EPFL Switzerland11 05 11 253D MINSTED fluorescence localization for nanoscopy and tracking in three spatial dimensionsJulius Bernhard Peters Max Planck Institute of Multidisciplinary Sciences Germany11 25 11 45Unraveling cellular complexity with Transient Adapters in highly multiplexed super resolution imagingFlorian Schueder cole Polytechnique F d rale de Lausanne EPFL Switzerland11 45 12 05Visualization of plasma membrane lipid packing asymmetry reveals a highly ordered outer leaflet and a flexible inner leaflet suggesting distinct leaflet functionsSatyajit Mayor Warwick Medical School United Kingdom12 05 13 50Lunch Exhibition12 30 13 30Concurrent lunch workshop by Thermo Fisher Scientific13 50 16 55Session 3 Probes optical pertubation toolsChair Ralf Jungmann Max Planck Institute for Biochemistry Germany13 50 14 10Invited talk From DNA Nanotechnology to biomedical insight Towards single molecule spatial omicsRalf Jungmann Max Planck Institute for Biochemistry Germany14 10 14 30High speed multiplexed DNA paint imaging of nuclear organization using an expanded sequence repertoireMicky Anand Indian Institute of Science Bangalore India14 30 14 50Quantitative PAINT microscopy of membrane proteins with self labeling protein tagsSoohyen Jang Goethe University Frankfurt Germany14 50 15 10Optifoot a method for recording protein binding sites on DNA for microscopy and sequence analysisGra vydas Lukinavicius Max Planck Institute for Multidisciplinary Sciences Germany15 10 15 55Coffee Break ExhibitionMeet the speakers with Satajit Mayor and Ralf Jungmann 15 55 16 15Recording the physiological history of cells with fluorescence labeling Kai Johnsson Max Planck Institute for Medical Research Germany16 15 16 35Genetically encoded tools based on luminescent proteinsAtsushi Miyawaki RIKEN Center for Brain Science JapanNot available on demand16 35 16 55Invited talk Using light to dissect and direct cellular organization and dynamicsLukas Kapitein Utrecht University The NetherlandsNot available on demand16 55 17 25Flash talks57 85 107 123 136 139 143 151 159 163 16717 25 19 25Poster Session 1 odd with beer and snacks19 25 21 00Conference dinner21 00 22 30Pub quiz Day 3 Friday 10 October 2025 Time Europe Berlin Speaker09 00 12 05Session 4 Imaging structure and function of molecules in situChair Gaia Pigino Human Technopole Italy09 00 09 20Invited talk Towards a mechanistic understanding of cilia assembly and transportGaia Pigino Human Technopole Italy09 20 09 40Physiological crystalline packing of cholesteryl esters in lipid droplets in mammalian tissue revealed by polarization microscopy and cryogenic serial lift out technologyWioleta Dudka EMBL Heidelberg Germany09 40 10 00Optical investigations of molecular glycocalyx architectureNathan Linus Sison Max Planck Institute for the Science of Light Germany10 00 10 45Coffee Break ExhibitionMeet the speakers with Atsushi Miyawaki Lukas Kapitein and Gaia Pigino10 45 11 05Invited talk The cellular behaviour of the apoptotic factor Apaf1 during cell deathWanda Kukulski University of Bern SwitzerlandNot available on demand11 05 11 25Imaging the folding of mitotic chromosomes and the assembly of the nuclear pore during human cell divisionJan Ellenberg SciLifeLab Sweden EMBL Heidelberg Germany11 25 11 45Super resolved imaging of native mRNA particle ultrastructureAlessandro Passera Research Institute for Molecular Pathology Austria11 45 12 05Invited talk New insights into oocyte meiosisMelina Schuh Max Planck Institute for Multidisciplinary Sciences GermanyNot available on demand12 05 13 35Lunch ExhibitionMeet the editors13 35 16 40Session 5 AI Image data modellingChair Carolina Wahlby SciLifeLab and Uppsala University Sweden13 35 13 55Invited talk Seeing is believing Alan Lowe Chan Zuckerberg Initiative USA13 55 14 15Mapping cells at scale from tissue volumes to community challenges in vEMAubrey Weigel Howard Hughes Medical Institute United States of America14 15 14 35Invited talk Combining cell morphology and spatial transcriptomicsCarolina Wahlby SciLifeLab and Uppsala University Sweden14 35 14 55Profiling cell death in 4 dimensions by combining lattice light sheet microscopy and machine learningNiall Geoghegan Walter and Eliza Hall Institute of Medical Research AustraliaNot available on demand14 55 15 40Coffee Break ExhibitionMeet the speakers with Wanda Kukulski Jan Ellenberg Melina Schuh Alan Lowe and Carolina Wahlby15 40 16 00Kolmogorov Arnold Networks KAN based fast nonlinear denoising filter for weak signal detection in fluorescence microscopyYannis Kalaidzidis Max Planck Institute of Molecular Cell Biology and Genetics Germany16 00 16 20Detecting and classifying artifacts associated with AI based image restorationSamantha Webster King s College London United Kingdom16 20 16 40Invited talk Accelerating the rate of scientific discovery through AI driven semantic unmixing of image dataFlorian Jug Human Technopole Italy16 40 17 10Flash talks54 58 60 64 84 90 106 110 128 140 144 146 156 17017 10 19 10Poster Session 2 even with beer and snacks19 15 01 00Castle dinner and party Day 4 Saturday 11 October 2025 Time Europe Berlin Speaker09 30 12 55Session 6 New approaches and applications of imaging technologiesChair Reto Fiolka University of Texas Southwestern Medical Center United States of America09 30 09 50Cryosectioning enhanced DNA PAINT for multimodal single molecule imaging across cells and tissuesJohannes Stein Max Planck Institute for Molecular Genetics Germany09 50 10 10Improving the performance and versatility of light sheet fluorescence microscopyReto Fiolka University of Texas Southwestern Medical Center United States of America10 10 10 30Highly dynamic mechanical transitions during Drosophila gastrulationJuan Manuel Gomez EMBL Heidelberg Germany10 30 10 50Scratching the surface unraveling the spatiotemporal dynamics of the bacterial cell envelopeGideon Mamou The Hebrew University of Jerusalem Israel10 50 11 35Coffee Break ExhibitionMeet the speakers with Florian Jug and Hideharu Mikami11 35 11 55Tracking rotational dynamics of single molecules using cylindrical polarization based interferometric scattering microscopyMilan Vala Academy of Sciences of the Czech Republic Czech RepublicNot available on demand11 55 12 15Cleam correlative light electron and atomic force microscopy on serial tokuyasu cryo sections for 3d volumetric reconstructionsPrabhu Prasad Swain EPFL Switzerland12 15 12 35Invited talk High speed fluorescence microscopy and beyondHideharu Mikami Hokkaido University Japan12 35 12 55Unraveling in real time Spatiotemporal imaging of cell death in tissueVivien Maltez University of California San Diego USA12 55 13 20Closing remarks and poster prize13 20 13 45Packed lunch and departure13 30Shuttle bus to the airport tickets available at registration desk Industry workshops For on site participants only The following industry workshops will be hosted by the sponsors of EMBO EMBL Symposium Seeing is believing imaging the molecular processes of life prior to the start of the event on Wednesday 8 October 2025 11 30 12 30 Imaging of spheroids and organoids using high content screening and light sheet microscopy by Jochen Gehrig Luxendo GmbH Bruker Lightfield 4D Keeping pace with the pulse of life LSM 990 and 910 One imaging platform Endless possibilities by Dr Annette Bergter Carl Zeiss Microscopy Advancing Confocal Imaging Unlocking Discovery with the new FLUOVIEW and Next Generation SilVIR Detection by B lent Peker Evident Europe Expanding the Imaging Horizon Innovations in Automation High Multiplexing Workflows and Spatial Phenotyping by J rgen Reymann Julia Roberti and Nariman Ansari Leica Microsystems Experience the Power of AI Ji Workflow and AX NSPARC for effortless super resolution imaging and advance analysis by Subash Chinnaraj and Sabrina Delattre Nikon Advancing Live Biological Research with Holotomography First Demonstration of Tomocube s New Compact System by Junhyung Park and Bruno Combettes Tomocube on Thursday 9 October 2025 12 30 13 30 From tissues to molecules Application insights with plasma FIB technologies by Radovan Spurny Thermo Fisher Scientific In order to read the abstract of each workshop please click on the corresponding links above Participation in this workshop is free of charge for registered on site conference attendees The available place is limited first come first served All registered conference attendees will receive an email with a registration link shortly All pre conference workshops will take place simultaneously therefore please choose the one you would be interested in the most EMBO training EMBO training session How to write a scientific paper Overview This training module introduces the fundamental elements of publishing scientific research focusing on the structure and content of a manuscript how to assemble effective figures and how to write impactful titles and abstracts Led by an experienced EMBO Press scientific editor participants will explore the strategic planning for publication including determining authorship organising data and selecting the most appropriate journal for submission The session will run for 4 hours on the first morning of the symposium and will provide an engaging and interactive learning environment Date Wednesday 8 October 2025 Time 8 30 12 30 Europe Berlin It will include hands on exercises group work and lively discussions to help participants develop a practical understanding of how to write a successful scientific paper Audience This training session is designed for a maximum of 20 PhD students and postdocs who want to improve their scientific writing and publishing skills Learning outcomes At the end of the module participants will Understand the purpose and the structure of each section of a scientific paper title and abstract introduction results materials and methods discussion references and data availability Gain practical experience in assembling figures and writing titles and abstracts Receive guidance from instructors and peer feedback to refine the critical components of a successful scientific manuscript Registration For more information and to register please contact annika diederich embo org Registration deadline 1 October 2025 The training session is limited to 20 participants who will be selected on a first come first served basis Selected participants must commit to attending the entire module Practical information Registration fees and abstract submission On site registration fees include admission conference materials meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Virtual registration fees include access to all of the talks livestreamed and on demand and facility to submit questions On site Academia 725On site PhD Student 625On site Industry 925On site Journal Editor 300Virtual Academia 225Virtual PhD Student 175Virtual Industry 275 Editors from scientific journals are allowed to attend at a reduced rate but asked to contribute to the conference in return by taking part in meet the editors sessions or other planned activities within the programme A letter to support your visa application will be issued on request once payment of the registration fee is confirmed We recommend that you book your visa appointment as soon as possible to avoid any delay with your visa application Accredited journalists may be eligible to register for complimentary press registration Registrants may be required to provide accreditation or equivalent proof of press membership after registration Please contact Iva Gavran for more information Please note that we do not offer complimentary registrations for editors of scientific journals Confirmation and payment Registration will be on a first come first served basis Your place can only be confirmed after payment of the registration fee If you are added to our waiting list please consider taking advantage of our offerings to participate virtually On site participants Types of payments accepted are international bank transfers and credit card payments Virtual participants We are only able to accept card payments In exceptional cases we can accept bank transfers Please contact events embl de for details Abstract submission Only participants registering to attend the on site event are eligible to submit an abstract Abstracts will not be accepted from virtual participants After registration you can submit your abstract via a separate link that will be provided in the email confirmation Alternatively you can access the link on the confirmation page directly after registering The same login credentials are used for both processes Please note Abstract body The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised Title The title should not exceed 20 words Only the first word of the title should start with a capital letter and the rest should be lowercase Authors and affiliations Please fill in the author s details as requested in the online form The compulsory fields are First Name Last Name Organisation Name Affiliation or Company Country and Email Kindly mark only one author in the role of First Author and please don t forget to indicate who will be the Presenter Please enter your co authors correctly via the system by adding accounts together with their organisation institute Do not copy paste them into the body of the abstract text as they will not be indexed in the abstract book Presentation types When submitting your abstract you can apply for an oral or poster presentation A selection process will take place with the results announced 2 3 weeks after the abstract submission deadline For detailed instructions on how to submit a conference abstract follow the instructions provided in this video Please check our FAQs pages for further information on how to submit an abstract Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of registration fee waivers travel grants and childcare grants Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course or conference Travel grant The travel grant will cover the cost of travel to an on site event airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from within Europe up to 1000 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from outside Europe up to 500 for any participant travelling to an EMBO Workshop up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Workshop up to 700 for any participant working in Croatia Czech Republic Estonia Greece Hungary Italy Lithuania Luxembourg Poland Slovenia and Turkey travelling to an EMBO Workshop Registration fees are only covered for EMBO Workshops The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant There is the possibility to apply for a childcare grant to offset child care costs incurred by participants speakers and organisers when attending a conference Eligible costs include but are not limited to fees for a baby sitter or child care facility and travel costs for a caregiver Please note that priority will be given to early stage researchers In order to apply for this grant you must be registered by the abstract submission deadline There is a limited amount of funding available for the childcare grants and funds will be distributed amongst eligible applicants Application On site participants You may apply for financial assistance when submitting your abstract In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Virtual participants If you are attending virtually you can apply for financial assistance in the submission portal by the abstract deadline Read the instructions on how to apply for financial assistance Only submissions for financial assistance will be accepted Presentation abstracts cannot be submitted here and will be declined In your application you will be asked to summarise your current work answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Selection The scientific organisers will select the recipients of all financial assistance during the abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection for registration fee waivers and travel grants is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Childcare grants will be allocated in the same timeframe 6 8 weeks before the event start date Please note that priority will be given to early stage researchers Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details View our list of external funding opportunities and information on attending a conference as an event reporter For further information about financial assistance please refer to the FAQ page Accommodation and travel Accommodation is not included in the conference registration fee As further changes in our events are possible you should book flights trains and hotels with flexible options and favourable cancellation conditions The hotels below have rooms on hold for participants until Saturday 6 September 2025 in some cases at special rates Please email the hotel directly quoting the booking code EES25 09 to confirm the exact price of the room Please note that as of 1 October 2025 Heidelberg City Council is introducing an overnight stay tax for tourists visiting Heidelberg including work related trips The cost will be 3 50 EUR per night for the first five nights of a consecutive stay and will be added to the hotel s nightly rate Please contact the individual hotel directly if you have any questions Hotel AnlageHotel Holl nder Hof Hotel MonptiHotel Bayrischer Hof Hotel ibis HeidelbergPremier Inn Heidelberg CityB B HotelISG Hotel Staycity Aparthotel HeidelbergExzellenz HotelLeonardo Hotel Heidelberg City CentreSteffi s Hostel HeidelbergHilton HeidelbergMeininger HeidelbergHotel Vier Jahreszeiten HeidelbergIntercity Hotel Heidelberg Travel information For travel information please see here Update below If you are travelling to the conference within Germany then you are eligible for the Deutsche Bahn Event Ticket called the Veranstaltungsticket in German This will result in a lower ticket price if your travel distance to Heidelberg is more than 100 km You need to provide proof of your event attendance when purchasing the ticket The Event Ticket is currently not available We are awaiting details on new offers Please check back for more information or get in touch with us at events embl org For more information in English see here or in German see here You can book your ticket here Conference shuttle buses Conference shuttle buses are free of charge for participants and depart from designated bus stops near the hotels to EMBL and back mornings and evenings The bus stops for this conference are Hotel Staycity Speyerer Str 7 Kurf rsten Anlage Opposite Main Train Station Hotel Premier Kurf rsten Anlage 23 Leonardo Hotel Heidelberg City Center Bergheimer Str 63 Neckarmuenzplatz Heidelberg Tourist Information Peterskirche Bus stop ISG Hotel Im Eichwald 19 View Conference shuttle bus stops and hotels in a larger map Please note that not every bus stop will be used for every event Further details Address EMBL Meyerhofstra e 1 69117 Heidelberg Germany For more information about accommodation and travel please refer to the FAQ page Onsite information Catering All meals and coffee breaks are included in the registration fee Our catering staff will prepare a wide variety of vegetarian meals meat and fish dishes soups pasta fresh fruit and vegetables as well as a variety of desserts Please wear your badge at all times when serving yourself No food or drinks are allowed in the auditorium Charging lockers There are lockers available next to the stairs leading down into the Auditorium You will find some of those equipped with sockets to charge your smartphone tablet etc Electricity and charging station In most places the electricity is 220 volts AC 50 cycles An adaptor and a plug that fits the German socket may be needed for your appliances laptop i e American Japanese etc A USB charging station for electronic devices is available at the registration desk EMBL merchandise If you are interested in purchasing EMBL merchandise products presented in the glass display in the registration area please email the EMBL shop to place an order or get in contact with your Course Organiser Kindly note the EMBL shop is only open upon request and all purchases must be made in cash Euros only Health and safety notes Please read EMBL s COVID 19 safety policy for on site events Do not smoke in any EMBL building Eating and drinking is prohibited in the Auditorium and all laboratories Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required The first aid room is located next to the ATC Registration Desk room 10 205 Dial the Emergency number 222 from any EMBL internal phone only Where is the accident What happened How many injured Emergency number 06221 387 7821 from mobile phones Please report all accidents to the conference officer at the registration desk In case of fire Press the nearest fire alarm button or the Emergency number 222 from any internal phone A loud fire alarm will go off if an evacuation is required On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting points Do not use the lifts Beyond first aid Please remember to bring your own medication if needed to the conference Note that the next pharmacy is a 4 minute drive from the EMBL but for many medications you will be required to see a doctor to get a prescription Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg In any case the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary Internet Wi Fi is available on campus using the EMBL Events network and the event specific password which will be provided on site The eduroam network secure worldwide roaming access service developed for the international research and education community is also available Lost and found Lost and Found items are kept at the registration desk until the end of the conference Luggage There are lockers available on site to store your luggage which require a 2 EURO coin to operate There is another luggage room on level E0 which is free to use but remains unlocked during the conference Nursing room There is a nursing room available in the ATC Rooftop Lounge on level A29 Photography During the conference an EMBL Photographer may be taking photos If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Printing We can help to print your boarding pass train ticket Please send it to events embl de and collect your print outs at the registration desk Room for prayer yoga and meditation There is a room for prayer meditation and yoga located on level E0 behind the Auditorium Please be respectful of others using the room Sightseeing A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing Travel to and from the venue During the event we provide conference shuttle buses to and from EMBL In addition there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time Information on the conference shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page Useful German expressions HelloHalloGoodbyeAuf Wiedersehen formal Tsch ss informal Good morningGuten MorgenGood afternoonGuten TagGood eveningGuten AbendGood nightGute NachtI m sorryEs tut mir leidExcuse me Entschuldigen Sie How are you Wie gehts I m fine thanks And you Mir geht es gut danke Und dir Ihnen What is your nameWie hei en Sie formal Wie hei t du informal My name is Ich hei e Do you speak English Sprechen Sie Englisch I don t understandIch verstehe nichtPlease speak more slowlyK nnen Sie bitte langsamer sprechenThank youDankesch nWhere is the toilet Wo ist die Toilette Please call me a taxiBitte rufen Sie mir ein TaxiHow do I get to Wie komme ich zum zur A beer two beers pleaseEin Bier zwei Bier bitteA glass of red white wine pleaseEin Glas Rot Wei wein bitteThe menu pleaseDie Speisekarte bitteIs there a local speciality Gibt es eine Spezialit t aus dieser Gegend I m vegetarianIch bin VegetarierIt was deliciousEs war hervorragendThe bill pleaseDie Rechnung bitteI have a headacheIch habe KopfschmerzenI have a sore throatIch habe HalsschmerzenMy stomach hurtsIch habe MagenschmerzenI m allergic toIch bin allergisch gegenI need a doctor who speaks English Ich brauche einen Arzt der Englisch spricht Virtual participation What s included Access to all the livestreamed talks Video library of the recorded talks during the event and for 4 weeks afterwards Please note at the request of individual speakers some talks are not recorded Facility to submit questions Please note that only on site participants are able to submit abstracts and participate in the poster sessions Event platform We are using an event platform for this conference More information about the platform will be shared ahead of the conference Guidelines Do not broadcast the conference to unregistered participants You are encouraged to tweet and post about the event Tweet unless the speaker specifically says otherwise but be mindful of unpublished data Please do not capture transmit or redistribute data presented at the meeting Additional information can be found in our Code of Conduct Health and well being It is important to stay healthy and move around especially when you are attending an event virtually We have put together a few coffee break stretches and yoga videos in the conference platform for you to enjoy during the event How to ask questions Please use the Q A function in the event platform If you have any other questions you can go to the Help Desk in the event platform Click on more on the top menu and click Help Desk Time zone The programme is planned based on the Europe Berlin time zone unless otherwise stated Please take your time zone into consideration when planning your attendance Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for participants page Sponsors Platinum sponsor Gold sponsor Silver sponsor Bronze sponsors Event sponsor 1NA Technologies Abberior Instruments Confocal HAMAMATSU PHOTONICS H BNER Photonics Intelligent Imaging Innovations Oxford Instruments Andor PicoQuant Teledyne Thermo Fisher Scientific TESCAN Visitron SystemsMedia partners Biobreeding a Sciepublish journal EMBO Reports an EMBO Press journal Microcscopy and Analysis a Wiley journal International Union of Biochemistry and Molecular Biology Medinformatics a Bon View Publishing journal Open Biology a Royal Society journal PLOS Biology a PLOS journal Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information on sponsoring possibilities If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9 Leaderboard 728 90 About EMBO EMBL Symposia promote scientific communication and collaboration in the European research area They provide scientists with a platform to discuss and exchange ideas on forward looking topics and new developments in the life sciences Topics emphasise upcoming developments and the interdisciplinary nature of related fields Jointly funded and organised by EMBO and EMBL and complementary to their respective courses workshops and conference programmes the symposia promote scientific communication and collaboration All symposia are held in the EMBL Advanced Training Centre ATC in Heidelberg Germany or virtually...

Jan Ellenberg, Jennifer Lippincott-Schwartz, Satyajit Mayor, Atsushi Miyawaki

EMBO | EMBL Symposium

EMBL Heidelberg, Virtual

6 October - 10 October 2025

Metagenomics bioinformatics at MGnify

Edit

October 06, 2025 00:002025CourseEMBL-EBI

Description Learn about the tools processes and analysis approaches used in the field of genome resolved metagenomics This course will cover the use of publicly available resources to manage share analyse and interpret metagenomics data focussing primarily on assembly based approaches The delivered content will involve participants learning via live lectures and presentations followed by live Q As with the trainers Practical experience will be developed in group activities and in computational exercises run using containerised tools on our training infrastructure...

EMBL-EBI Training

EMBL-EBI

2 October 2025

A guide to UniProt for students

Edit

October 02, 2025 15:002025WebinarVirtual

Description UniProt provides the scientific community with a comprehensive high quality and freely accessible resource of protein sequence and functional information This webinar will guide you through ways in which students and researchers at all career stages may take a structured approach to access the data in the UniProtKB and Proteomes sections of the UniProt protein function database The webinar will discuss the types of data that can be accessed and using sequence analysis tools how this data can be analysed to answer biological questions We will demonstrate how to find the function of a protein how the protein components of a pathway may be identified features of proteins of interest can be compared similar sections of sequence can be sought in other species and how whole data sets containing all the proteins expressed in an organism can be obtained By accessing sequence structural and functional data through UniProt we want researchers to be part of data s biological journey and support further work and adventures along the way...

Virtual

1 October 2025

Introduction to pangenomes and why they are worth exploring

Edit

October 01, 2025 14:302025WebinarVirtual

Description Pangenomes offer an alternative approach to using a singular linear reference genome which is becoming increasingly important as both the volume and diversity of genomic data grows rapidly However transitioning to pangenomics also brings along new terminology and challenges both biological and computational all of which are less clearly defined than in the conventional linear reference world Here we ll attempt to define some key differences in pangenomics and how they can improve future genomic analyses...

Virtual

30 September 2025

Edit

September 14, 2025 00:002025CourseEMBL-EBI

Description This EMBO Practical course will introduce concepts methods and tools for carrying out infectious disease modelling as well as for developing models further by leveraging the power of genomics Modelling infectious diseases can help to understand the mechanisms of pathogen evolution and predict the development of epidemics This had an immense impact on the COVID 19 pandemic and is crucial for the general surveillance of pathogens In this course participants will learn about compartmental models such as Susceptible Infectious Recovered SIR models how to adapt them to a pathogen of their interest and the differences between stochastic and deterministic models Taking this further participants will apply these models to epidemic settings in order to predict changes in case numbers and disease severity Additionally the participants will learn how to implement and adapt genomics informed models for pathogen evolution and they will learn how to make use of genomics to create timed phylogenies and reconstruct ancestral states Finally bringing together transmission modelling and genomic data participants will learn about phylodynamic models and how this can help to detect changes in case numbers and pathogenicity earlier and more reliably than with transmission models alone...

Barbara Etzi

EMBL-EBI

14 September - 19 September 2025

Advanced methods in bioimage analysis

Edit

September 14, 2025 00:002025CourseEMBL Heidelberg, Virtual

Description OverviewTrainers speakers staffProgrammePractical informationSponsorsMedia kit Overview This course will take place at EMBL Heidelberg with the option to attend virtually Course overview Bioimage analysis has become a keystone of biological research the deluge of data produced by increasingly advanced microscopes calls for experts able to guide life scientists in the methods and software to be used to produce quantitative knowledge from this data Due to the complexity of the data without such expert guidance it is very likely that image analysis algorithms may be applied incorrectly possibly even producing erroneous results Moreover the diversity of imaging modalities analysis algorithms and software solutions is growing so rapidly that even experts are overwhelmed This advanced course concentrates on teaching cutting edge concepts and tools for quantitative image analysis and will seek to upgrade the competencies of future bioimage analysis experts on both theoretical algorithm advancements as well as on practical implementation skills Audience This course is aimed at early career scientists and staff scientists working in microscopy or image analysis facilities who already have experience in bioimage analysis Moreover participants should already provide or show a clear intent of providing bioimage analysis support to other researchers with less or no experience in bioimage analysis In selecting participants we look for scientific excellence immediate application of the methods learned motivation to disseminate and networking skills We expect a solid background in bioimage analysis and at least basic programming skills Modules resources Image analysis workflow and data management Using AI and natural language processing for image analysis Cells and particles tracking Spatial statistics and omics integration Deep learning for bioimage analysis Image based behaviour modeling Spatial modeling and shape analysis Open science reproducible research and women in science Learning outcomes For each module participants will learn both theoretical and practical aspects of the latest developments in the fields of bioimage analysis concepts and tools After this course participants are expected to be able to confidently operate and interface with a representative selection of open and closed source image analysis software Participants should be able to apply what they have learnt to their own image data as well as to image data of their colleagues What past participants say about the course The EMBL practical course on Advanced Methods in Bioimage Analysis represents a turning point in my career As a Ph D student having the opportunity to meet network and learn with the most experienced researchers in this topic changed how I analyze my images and speed up my image analysis workflows Fernanda Garcia Fossa Institute of Biology University of Campinas This event has been granted the following EMBO sustainability badge Grade 3 of 3 Trainers speakers staff Speakers trainer and staff Philippe Andrey INRAE Versailles France Ignacio Arganda Carreras University of the Basque Country UPV EHU Spain Fynn Beuttenm ller EMBL Heidelberg Germany Beth Cimini Broad Institute USA Robert Haase University of Leipzig Germany Wangjun Hu Heidelberg University Germany Anna Klemm Scilifelab Uppsala University Sweden Nikolai K hler Heidelberg University Germany Anna Kreshuk EMBL Heidelberg Germany Matthew McCormick fideus labs USA Perrine Paul Gilloteaux CNRS UAR BioCore Nantes University France Norman Rzepka scalable minds Germany Suganya Sivagurunathan Scilifelab Uppsala University Sweden Jean Yves Tinevez Institut Pasteur France Pavel Tomancak Max Planck Institute of Molecular Cell Biology and Genetics Germany Christian Tischer EMBL Heidelberg Germany Britta Velten Heidelberg University Germany Carolina W hlby Scilifelab Uppsala University Sweden Virginie Uhlmann University of Z rich Switzerland Kevin Yamauchi ETH Z rich Switzerland Scientific organisers Ignacio Arganda Carreras University of the Basque Country UPV EHU Spain Anna Klemm Scilifelab Uppsala University Sweden Perrine Paul Gilloteaux University of Nantes France Christian Tischer EMBL Heidelberg Germany Course organisers Julia Patricia Nohle Course and Conference Officer EMBL Heidelberg Germany Irena Provaznikova Senior Scientific Training and Digital Learning Manager EMBL Heidelberg Germany Programme Are you on social media Post using EMBOBioImage and don t forget to tag EMBLEvents Please note Some pre course work such as watching pre recordings and protocol reading with estimated time 0 10 hours will be required and will be shared in advance of the course Some speakers may need to join virtually to give their lecture or Q A and the programme is subject to change For registered participants recorded talks will be accessible on demand for 4 weeks after the end of the event unless indicated otherwise Day 0 Onboarding Monday 08 September 2025 Time Europe Berlin SessionLocation14 00 15 00Virtual Onboarding Testrun Zoom testingPre course material material on eCampusOnline Day 1 Sunday 14 September 2025 Time Europe Berlin SessionLocation12 45 13 00Bus from ISG to EMBLISG Hotel13 00 13 30WelcomeWelcome to EMBL House notes safety and course overviewCourtyard Room A B13 30 15 00Networking part 1 Virtual poster sessionGroup sessionsCourtyard Room A B15 00 15 30Coffee breakCourtyard Room A B15 30 17 00Networking part 2 Virtual poster sessionFlash talksCourtyard Room A B17 00 18 00Treasure hunt onsite participants only Courtyard Room A B18 00 19 00DinnerEMBL Canteen19 00 20 00Networking part 3 Virtual poster sessionATC Rooftop Lounge20 00Bus from EMBL to ISG Hotel Day 2 Monday 15 September 2025 Time Europe Berlin SessionLocation08 40 09 00Transport from ISG to EMBL09 00 10 45Overview of the day 5 min Practical session 1 Image Analysis workflow and data managementIncluding Q A on pre recorded lectureVirginie Uhlman University of Z rich Switzerland Assisted by Perrine Paul Gilloteaux CNRS UAR BioCore Nantes University France Christian Tischer EMBL Heidelberg GermanyComputer Training Lab10 45 11 15Coffee break and meet the trainersOutside CTL11 15 13 00Practical session 1 Image Analysis workflow and data management continued Including Q A on pre recorded lecture Virginie Uhlman University of Z rich Switzerland Assisted by Perrine Paul Gilloteaux CNRS UAR BioCore Nantes University France Christian Tischer EMBL Heidelberg GermanyComputer Training Lab13 00 14 00Lunch short walk in the forest optional EMBL Canteen14 00 14 30Lecture 1 Women in sciencePerrine Paul Gilloteaux CNRS UAR BioCore Nantes University France14 30 16 15Practical session 2 Using AI and natural language processing to help image analysisIncluding Q A on pre recorded lecture breaks as needed Led by Robert Haase University of Leipzig Germany Assisted by Ignacio Arganda Carreras University of the Basque Country UPV EHU Spain Christian Tischer EMBL Heidelberg GermanyComputer Training Lab16 15 16 45Coffee break and meet the trainersOutside CTL16 45 18 30Practical session 2 Using AI and natural language processing to help image analysis continued with debrief Led by Robert Haase University of Leipzig Germany Assisted by Ignacio Arganda Carreras University of the Basque Country UPV EHU Spain Christian Tischer EMBL Heidelberg GermanyComputer Training Lab18 30 20 15Pizza Dinner Onsite NetworkingATC Rooftop Lounge20 15Bus from EMBL to ISG Day 3 Tuesday 16 September 2025 Time Europe Berlin SessionLocation08 40 08 55Bus from ISG to EMBL Heidelberg08 55 09 00Overview of the dayCourtyard Room A B09 00 10 45Practical session 3 TrackingIncluding Q A on pre recorded lecture Led by Jean Yves Tinevez Institut Pasteur France Assisted by Ignacio Arganda Carreras University of the Basque Country UPV EHU Spain Perrine Paul Gilloteaux CNRS UAR BioCore Nantes University FranceComputer Training Lab10 45 11 15Coffee breakOutside CTL11 15 13 00Practical session 3 Tracking continued Including Q A on pre recorded lecture Led by Jean Yves Tinevez Institut Pasteur France Assisted by Ignacio Arganda Carreras University of the Basque Country UPV EHU Spain Perrine Paul Gilloteaux CNRS UAR BioCore Nantes University FranceComputer Training Lab13 00 14 00Lunch short walk in the forest optional EMBL Canteen14 00 15 30Practical session 4 Behavior Modeling Led by Kevin Yamauchi Assisted by Ignacio Arganda Carreras University of the Basque Country UPV EHU Spain Perrine Paul Gilloteaux CNRS UAR BioCore Nantes University FranceComputer Training Lab15 30 16 00Coffee break and meet the speakerOutside CTL16 00 16 15Course group photoOutside ATC16 00 18 00Practical session 4 Behavior Modeling continued with debrief Led by Kevin Yamauchi Assisted by Ignacio Arganda Carreras University of the Basque Country UPV EHU Spain Perrine Paul Gilloteaux CNRS UAR BioCore Nantes University FranceComputer Training Lab18 00 18 30Lecture 2 Research Integrity virtual talk Beth Cimini Broad Institute USACourtyard Room A B18 30 20 15Tapas Dinner Onsite NetworkingRooftop Lounge20 15Bus from EMBL to ISG Day 4 Wednesday 17 September 2025 Time Europe Berlin SessionLocation08 40 08 55Bus from ISG to EMBL Heidelberg08 55 09 00Overview of the dayCourtyard Room A B09 00 10 45Practical session 5 Spatial statistics and omics integrationIncluding Q A on pre recorded lecture Led by Britta Velten Heidelberg University Germany Assisted by Anna Klemm Scilifelab Uppsala University Sweden Nikolai K hler and Wangjun Hu Heidelberg University GermanyComputer Training Lab10 45 11 15Coffee break and meet the speakerOutside CTL11 15 13 00Practical session 5 Spatial statistics and omics integration continued Including Q A on pre recorded lecture Led by Britta Velten Heidelberg University Germany Assisted by Anna Klemm Scilifelab Uppsala University Sweden Nikolai K hler and Wangjun Hu Heidelberg University GermanyComputer Training Lab13 00 14 00LunchEMBL Canteen14 00 15 00Keynote lecture Image based exploration of molecular and morphological components of tissueCarolina W hlby Uppsala University SwedenCourtyard Room A B15 00 16 45Round Table discussion Led by Anna Klemm and Suganya Sivagurunathan Scilifelab Uppsala University SwedenCourtyard Room A B16 45 17 00Transport from EMBL to ISGEMBL19 00 19 15Bus from ISG downtownISG19 15 21 30Downtown Heidelberg course dinnerat Oskar Vinothek RestaurantDowntown Day 5 Thursday 18 September 2025 Time Europe Berlin SessionLocation08 40 09 00Bus from ISG to EMBL Heidelberg09 00 10 00Lecture 4 Introduction to working with OME Zarr Tutorial Christian Tischer EMBL Heidelberg GermanyJosh Moore German BioImaging GermanyComputer Training Lab10 00 11 00Lecture 5 Software presentation and key challenge subsequent Q ANorman Rzepka scalable minds GermanyCourtyard Room A B11 00 12 00Lecture 6 Open science and bioimage analysis virtual Pavel Tomancak Max Planck Institute of Molecular Cell Biology and Genetics GermanyCourtyard Room A B12 00 13 00LunchEMBL Canteen13 00 14 00Lecture 7 Software presentation and key challenge subsequent Q A virtual Matthew McCormick fideus labs USACourtyard Room A B14 00 15 45Software Practical Work on your own data with Software representativesComputer Training Lab15 45 16 15Coffee break and meet the speakersOutside CTL16 15 18 00Software Practical Work on your own data with Software representativesComputer Training Lab18 00Bus from EMBL to ISGATC Entrance18 30 21 00BBQ and networking at ISG HotelISG Hotel Day 6 Friday 19 September 2025 Time Europe Berlin SessionLocation08 45 09 00Bus from ISG to EMBL Heidelberg09 00 10 45Practical session 6 AI for Life SciencesIncluding Q A on pre recorded lectureLed by Fynn Beuttenm ller EMBL Heidelberg Germany Assisted by Ignacio Arganda Carreras University of the Basque Country UPV EHU Spain Anna Klemm Scilifelab Uppsala University SwedenComputer Training Lab10 45 11 15Coffee break and meet the trainersOutside CTL11 15 13 00Practical session 6 AI for Life Sciences continued Including Q A on pre recorded lecture Led by Fynn Beuttenm ller EMBL Heidelberg Germany Assisted by Ignacio Arganda Carreras University of the Basque Country UPV EHU Spain Anna Klemm Scilifelab Uppsala University Sweden Computer Training Lab13 00 14 00Lunch short walk in the forest optional EMBL Canteen14 00 15 45Practical session 7 Statistical spatial analysis and modeling with BIP Including Q A on pre recorded lecture Led by Philippe Andrey INRAE Versailles France Assisted by Perrine Paul Gilloteaux CNRS UAR BioCore Nantes University France Christian Tischer EMBL Heidelberg GermanyComputer Training Lab15 45 16 00Coffee break and meet the trainersOutside CTL16 00 17 45Practical session 7 continued Statistical spatial analysis and modeling with BIP Including Q A on pre recorded lecture Led by Philippe Andrey INRAE Versailles France Assisted by Perrine Paul Gilloteaux CNRS UAR BioCore Nantes University France Christian Tischer EMBL Heidelberg GermanyComputer Training Lab17 45 18 00Wrap up Course debrief by organizers with discussionCourtyard Room A B18 00Bus downtown and to train station Practical information Registration fees and motivation letter The course is limited to 20 onsite and 6 virtual participants For selection purposes please note that your application will not be considered without a letter of motivation Registration Registration fees include admission course materials meals and coffee breaks This EMBO course includes accommodation and transportation to and from the ISG Hotel to the venue Academia 500PhD Student 500Industry 1100Virtual Academia PhD 190Virtual Industry 250 A letter to support your visa application will be issued on request once payment of the registration fee is confirmed We recommend that you book your visa appointment as soon as possible to avoid any delay with your visa application Confirmation and payment The registration fee should be paid only after acceptance to the course The results will be announced approximately 2 3 weeks after the application deadline Motivation letter submission After you have logged in and successfully registered you will receive an email asking you to submit your motivation letter Click on the link provided and enter your motivation letter in the text box provided Alternatively you can submit your motivation letter by clicking on the link on the confirmation page directly after registering Instructions Include your relevant skills experience and qualifications showing why you would be suitable for the course Explain why you would like to attend including what you can contribute and how you think you will benefit from the course Please note The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised For detailed instructions please watch our video on how to submit a course motivation letter Further details For further information about registration and motivation letter submission please refer to the FAQ page Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of registration fee waivers travel grants and childcare grants Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course Travel grant The travel grant will cover the cost of travel airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Course within Europe up to 1000 for participants travelling to an EMBL Course from outside Europe up to 500 for any participant travelling to an EMBO Practical Course up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Practical Course Registration fees are only covered for EMBO Practical Courses The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grants There is the possibility to apply for a childcare grant to offset child care costs incurred by participants speakers trainers and organisers when attending a course Eligible costs include but are not limited to fees for a babysitter or child care facility and travel costs for a caregiver Please note that priority will be given to early stage researchers There is a limited amount of funding available for the childcare grants and funds will be distributed amongst eligible applicants Boehringer Ingelheim Fonds travel grant Applies to selected courses only Availability will be indicated during the abstract or motivation letter submission process This grant covers costs related to your attendance to the course registration travel and accommodation costs The grant is restricted to PhD students and postdocs who conduct basic biomedical research Whether you are eligible to apply for a travel grant depends on when you received your university entrance qualification e g Abitur A Levels High School Diploma Final State Examination for PhD and MD students as well as graduates the university entrance qualification must not have been obtained more than 11 years ago at the time of the envisaged course for postdocs the university entrance qualification must not have been obtained more than 13 years ago at the time of the envisaged course Application If you are attending virtually you can apply for financial assistance in the submission portal by the abstract deadline Read the instructions on how to apply for financial assistance Only submissions for financial assistance will be accepted Presentation abstracts cannot be submitted here and will be declined In your application you will be asked to summarise your current work answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application For some events applications for Childcare Grants will still be done by email Information about the grant will be sent out shortly after the abstract motivation letter deadline Please contact the event Conference Officer if you have any questions Selection The scientific organisers will select the recipients of registration fee waivers during the participant selection process for courses Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection for registration fee waivers and travel grants is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Childcare grants will be allocated in the same timeframe 6 8 weeks before the event start date Please note that priority will be given to early stage researchers Further details Check out this list of external funding opportunities For further information about financial assistance please refer to the FAQ page Accommodation and travel Hotel Accommodation in twin rooms including breakfast is included in the registration fee Accommodation will be booked for the selected participants at the ISG Hotel for the default dates of 13 to 19 6 nights In case you would like to have a single room please let the hotel know and please note that you will be required to pay an additional cost of 22 50 per night availability of single rooms may be limited This should be paid by you directly to the ISG Hotel during your stay We recommend that all course participants stay at the ISG Hotel for the course Travel information For travel information please see here If you are travelling to the conference within Germany then you are eligible for the Deutsche Bahn Event Ticket called the Veranstaltungsticket in German This will result in a lower ticket price if your travel distance to Heidelberg is more than 100 km You need to provide proof of your event attendance when purchasing the ticket For more information in English see here or in German see here You can book your ticket here Local transport Shuttle buses will go from the ISG Hotel to EMBL and back mornings and evenings A bus schedule and location of the bus stops will be made available prior to the meeting Further details Address EMBL Heidelberg Meyerhofstra e 1 69117 Heidelberg Germany For more information about accommodation and travel please refer to the FAQ page On site information Catering All meals and coffee breaks are included in the registration fee Our catering staff will prepare a wide variety of vegetarian meals meat and fish dishes soups pasta fresh fruit and vegetables as well as a variety of desserts Please wear your badge at all times when serving yourself No food or drinks are allowed in the laboratories Electricity and charging station In most places the electricity is 220 volts AC 50 cycles An adaptor and a plug that fits the German socket may be needed for your appliances laptop i e American Japanese etc A USB charging station for electronic devices is available at the registration desk EMBL Merchandise If you are interested in purchasing EMBL merchandise products presented in the glass display in the registration area please email the EMBL shop to place an order or get in contact with your Course Organiser Kindly note the EMBL shop is only open upon request and all purchases must be made in cash Euros only Health and safety notes Please read EMBL s COVID 19 safety policy for on site events Do not smoke in any EMBL building Eating and drinking is prohibited in all laboratories Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required The first aid room is located next to the ATC Registration Desk room 10 205 Dial the Emergency number 222 from any EMBL internal phone only Where is the accident What happened How many injured Emergency number 06221 387 7821 from mobile phones Please report all accidents to the conference officer at the registration desk In case of fire Press the nearest fire alarm button or the Emergency number 222 from any internal phone A loud fire alarm will go off if an evacuation is required On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting points Do not use the lifts Beyond first aid Please remember to bring your own medication if needed to the conference Note that the next pharmacy is a 4 minute drive from the EMBL but for many medications you will be required to see a doctor to get a prescription Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg In any case the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary Internet Wi Fi is available on campus Log in using the EMBL Events network and the event specific password which will be provided on site The eduroam network secure worldwide roaming access service developed for the international research and education community is also available Lost and found Lost and Found items are kept at the registration desk until the end of the conference Luggage There are lockers available on site to store your luggage which require a 2 EURO coin to operate There is another luggage room on level E0 which is free to use but remains unlocked during the conference Nursing room There is a nursing room available in the ATC Rooftop Lounge on level A29 Photography During the conference an EMBL Photographer may be taking photos If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Printing We can help to print your boarding pass train ticket Please send it to events embl de and collect your print outs at the registration desk Room for prayer yoga and meditation There is a room for prayer meditation and yoga located on level E0 behind the Auditorium Please be respectful of others using the room Sightseeing A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing Travel to and from the venue During the event we provide conference shuttle buses to and from EMBL In addition there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time Information on the shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page Map to walk from ISG Hotel to EMBL Technical requirements and event software Technical requirements Below you will find the software and technical requirements for this course You will need admin rights to be able to install the software on your computer and we recommend you try this before the course If you do not have admin rights please contact your technical support team in advance to make sure the software can be installed Additional software The EMBL eCampus learning platform will be used to collaborate communicate and network with all of the course participants All participants will receive information on how to join shortly before the course We recommend using Chrome Safari or Mozilla Firefox browsers for eCampus Zoom will be used for the live talks and Q A sessions More information will be provided closer to the start of the course Other information While using the software during the course please make sure you have nothing else using your bandwidth We recommend using a wired connection Virtual participation guidelines Guidelines Do not broadcast the course to unregistered participants Do not share your login details with others You are encouraged to tweet and post about the event Tweet unless the speaker specifically says otherwise but be mindful of unpublished data Please do not capture transmit or redistribute data presented at the meeting Video library of the recorded talks during the event and for 4 weeks afterwards Please note at the request of individual speakers some talks are not recorded Additional information can be found in our Code of Conduct Health and well being It is important to stay healthy and move around especially when you are attending an event virtually We have put together a few coffee break stretches and yoga videos in eCampus for you to enjoy during the event How to ask questions Questions during and after the talks can be asked in the live streaming platform If time runs out or you think of a question later you can use the EMBL eCampus forum or send a direct message to the speaker trainer Time zone The programme is planned based on the Europe Berlin time zone unless otherwise stated As many virtual participants are attending from around the world we do our best to accommodate as many time zones as possible when creating the programme Please take your time zone into consideration when planning your attendance Additional information Please find additional information including FAQs and terms and conditions on our Information for Participants page Sponsors Event sponsors Media partners Microcscopy and Analysis a Wiley journal Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other events or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9...

Ignacio Arganda-Carreras, Anna Klemm, Perrine Paul-Gilloteaux, Christian Tischer

EMBO Practical Course

EMBL Heidelberg, Virtual

9 September - 12 September 2025

Developmental metabolism: flows of energy, matter, and information

Edit

September 09, 2025 00:002025ConferenceEMBL Heidelberg, Virtual

Description OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Conference overview The fundamental question of the role of metabolism in development has seen a revival in interest over recent years creating the need for the first edition of this workshop in 2023 This second edition is set to reunite the community two years on and to ensure the ongoing interactions that can propel progress in developmental metabolism In this rapidly advancing field metabolomic methods play a crucial role in unraveling complex processes The workshop will again aim to bring together researchers from diverse backgrounds developmental biology genetics epigenetics ecology physics and math to provide the developmental metabolism community with cutting edge research and methodologies applied across scales insights into the latest advancements in metabolomic techniques and their application to developmental biology New for 2025 will be an increased integration of tool development and technologies and an added focus on novel metabolomic approaches Topics over the six sessions will include Physical bioenergetics Metabolic constraints in developing systems Metabolic control who got the power Metabolic signaling in time and space metabolites as morphogens New enabling technologies to study metabolism in time and space Metabolic plasticity facing ever changing internal and external environments This event has been granted the following EMBO sustainability badge Grade 2 of 3 Speakers Asaph Aharoni Weizmann Institute of Science Israel Aydan Bulut Karslioglu Max Planck Institute of Molecular Cell Biology and Genetics Germany Clotilde Cadart Institut Cochin France Margarete Diaz Cuadros Harvard Medical School USA Aissam Ikmi EMBL Heidelberg Germany Heidi Lempradl Van Andel Institute USA Heidi McBride McGill University Canada Shyh Chang Ng Chinese Academy of Sciences China Jun Park University of California Los Angeles USA Markus Ralser Charit Universit tsmedizin Berlin Germany Teresa Rayon Babraham Insitute UK Matthew Regan University of Montreal Canada Remote Berna Sozen Yale School of Medicine USA Marion Walhout UMass Chan Medical School USA Remote Jan Zylicz University of Copenhagen Denmark Scientific organisers Alexander Aulehla EMBL Heidelberg Germany Heather Christofk University of California Los Angeles USA Heidi Lempradl Van Andel Institute USA Jonathan Rodenfels Max Planck Institute of Molecular Cell Biology and Genetics Germany Conference organiser Nathalie Sneider EMBL Heidelberg Germany Programme Are you on social media Post using EMBODevMet and don t forget to tag EMBLEvents For registered participants recorded talks will be accessible on demand for 4 weeks after the end of the event unless indicated otherwise Please note that the programme is subject to change Some speakers may need to join virtually to give their talk The poster listing is available here The bus schedule for this conference is available here Day 1 Tuesday 9 September 2025 Time Europe Berlin Speaker12 15 13 45Registration and light refreshmentskindly sponsored by Van Adel Institute13 45 13 55Opening remarks by organisers13 55 16 10Session 1 Chair Heidi Lempradl Van Andel Institute USA13 55 14 25Functional organization and evolution of metabolism Markus Ralser Charit Universit tsmedizin Berlin Germany14 25 14 40The role of metabolism during hydra tissue patterning and regenerationMaryl ne Bonvin Friedrich Miescher Institute for Biomedical Research FMI Switzerland14 40 15 10TCA cycle rewiring underpins early developmentJan Zylicz Novo Nordisk Foundation Center for Stem Cell Medicine University of Copenhagen University of Copenhagen Denmark15 10 15 40Coffee Break and Meet the speakers Markus Ralser Jan Zylicz 15 40 15 55Compartmentalisation of metabolism in somatic cells sustains germ cell survival through lactate shuttling in the Drosophila testisMarc Amoyel Umiversity College London UK15 55 16 10Dissecting Growth and Energy Scaling in Drosophila Using Integrated Imaging and Metabolic ProfilingYoumna Atieh Institut de Biologie du D veloppement de Marseille IBDM France16 10 17 10Breakout session 1Discussion within individual discussion groups16 10 16 25 Scientific organisers meeting with group facilitators participants to make their way to the section of the Helix reserved for their group 16 25 17 10 Group discussion17 10 17 40Flash talk session 1 odd numbers 3 minutes each 1 slide 35 Christopher Bell 37 James Cleland 39 Gillian Davidson 41 Bianca Habermann 45 Roksolana Kobylinska 49 Manohara Mahadeva 51 Liliana Pi eros 55 Bhabesh Tripathy17 40 19 10Poster session 1 odd numbers19 10 20 10Dinner in Canteen20 10 22 00Welcome reception in ATC Rooftop lounge Day 2 Wednesday 10 September 2025 Time Europe Berlin Speaker09 00 12 00Session 2Chair Jonathan Rodenfels Max Planck Institute of Molecular Cell Biology and GeneticsGermany09 00 09 30Exploring the role of protein metabolism in developmental tempo Teresa Rayon Babraham Institute UKNot available on demand09 30 09 45The role of nucleotide biosynthesis regulation in neuromuscular developmentJustin Kollman University of Washington USA09 45 10 00A comparative analysis of the energetics of early development across animal phylaVinca Yadav Max Planck Institute of Molecular Cell Biology and Genetics Germany10 00 10 30Metabolic regulation of early embryogenesis integrating patterning and timingAydan Bulut Karslioglu Max Planck Institute for Molecular Genetics GermanyNot available on demand10 30 11 00Coffee Break and Meet the speakersThere will be a conference group photo at the start of the coffee break at 10 3011 00 11 30Selective utilization of glucose metabolism guides mammalian gastrulationBerna Sozen Yale School of Medicine USANot available on demand11 30 11 45Decoding meiotic metabolism divergent energy pathways and nucleotide synthesis in spermatogenic cellsNina Mayorek The Hebrew University of Jerusalem Israel11 45 12 00Metabolic rewiring drives tolerance to oncogenic mutations in skin stem cellsAnupama Hemalatha Friedrich Meischer Institute for Biomedical Sciences SwitzerlandNot available on demand12 00 13 30Lunch and Meet the Editors from 13 00 13 30 withInes Alvarez Garcia PLOS BiologySalvatore Fabbiano Cell PressIeva Gailite EMBO Press13 30 15 00Session 3Chair Berna Sozen Yale School of Medicine USA13 30 14 00Genome scale models of metabolic wiring and rewiringMarian Walhout University of Massachusetts Chan Medical School USA Remote speaker 14 00 14 15Thermal constraints on the mitochondrial proteome refine the hot mitochondria hypothesisPablo Rivera Mej as EMBL Heidelberg Germany14 15 14 45Metabolic profiling flux thermodynamics control and beyondJun Park University of California Los Angeles USA14 45 15 15Coffee Break and Meet the speakers Teresa Rayon Berna Sozen Jun Park 15 15 16 15Breakout session 2Discussion within individual discussion groups16 15 16 45Flash talk session 2 even numbers 3 minutes each 1 slide 36 Johann Sora Blakytny 38 Gloria Brea Calvo 40 Jaroslav Ferenc 42 Mona Hosny 44 Shuzo Kato 48 Junjie Lui 50 Hidenobu Miyazawa 52 Kathrin Schmeisser 54 Mariano Stornaiuolo 56 Yu Wei16 45 18 15Poster session 2 even numbers18 15 19 45Dinner in Canteen19 45 22 00All posters viewing and drinks Day 3 Thursday 11 September 2025 Time Europe Berlin Speaker09 00 12 00Session 4Chair Jan Zylicz University of Copenhagen Denmark09 00 09 30Spatial metabolomics of skeletal muscle regenerationShyh Chang Ng Chinese Academy of Sciences China09 30 09 45Metabolic control of cell fate specification and morphogenesis in a mammalian embryo modelAlba Villaronga Luque MPI CBG Germany09 45 10 00Developmental programs of nutrient acquisition influence oncogenic competence in YAP driven liver cancerMikaela Wong Peter MacCallum Cancer Centre Australia10 00 10 30Mitochondria derived vesicles connect mitochondria tolysosomes at the nexus of immune signaling and celldeathHeidi McBride McGill University Canada10 30 11 00Coffee Break and Meet the speakers Shyh Chang Ng Heidi McBride 11 00 11 30The sea anemone dilemma to grow or not to grow tentacles Aissam Ikmi EMBL Heidelberg GermanyNot available on demand11 30 11 45TCA cycle rewiring underpins implantation and histone acetylation programmingEleni Kafkia Novo Nordisk Foundation Center for Stem Cell Medicine University of Copenhagen Denmark11 45 12 00Membrane potential as an overarching controller of somitogenisis in chick embryo from metabolism to biomechanics and signal transductionMagdalena Kowacz Institute of Animal Reproduction and Food Research Polish Academy of Sciences Poland12 00 13 30Lunch13 30 16 15Session 5 Chair Heather Christofk University of California Los AngelesUSA13 30 14 00Whole embryo energy expenditure varies cell size across Xenopus species Clotilde Cadart Institut Cochin FranceNot available on demand14 00 14 15Nature as a great sculptor a lesson from ferroptotic trigger wavesSheng S H Chen Academia Sinica Taiwan14 15 14 30Development dependent mitochondrial stress response activation in the heartMilica Popovic Uniklinik K ln Germany14 30 15 00Gut microbial contributions to hibernation metabolismMatthew Regan University of Montreal Canada Remote speaker 15 00 15 30Coffee Break and Meet the speakers Aissam Ikmi Clotilde Cadart 15 30 16 00A gas and brake mechanism in the plant growth defense tradeoffAsaph Aharoni Weizmann Institute of Science Israel16 00 16 15The energetic cost for molecular synchronization theoretical insights from cyanobacterial circadian clockDongliang Zhang Max Planck Institut f r Physik komplexer Systeme Germany16 15 17 15Breakout session 3Discussion within individual discussion groups17 15 17 45Coffee break17 45 18 45Breakout sessions discussion summary auditorium 18 45 20 45Conference dinner in Canteen20 45 23 00Conference party with live music from the Popcakes Day 4 Friday 12 September 2025 09 30 12 00Session 6 Chair Alexander Aulehla EMBL Heidelberg Germany09 30 10 00Regulation of species specific developmental rates by redox metabolismMargarete Diaz Cuadros Massachusetts General Hospital Harvard Medical School USA10 00 10 30Glycolytic activity instructs germ layer proportions through regulation of Nodal and Wnt signallingKristina Sukanya Stapornwongkul Institute of Molecular Biotechnology Austria10 30 10 45From dormancy to new life metabolic activation of the embryoChristoph G belein Whitehead Institute Massachusetts Institute of Technology United States of America10 45 11 15Coffee Break and Meet the speakers Asaph Aharoni Margarete Diaz Cuadros 11 15 11 30Fuelling fate lineage specific metabolic remodelling directs cell fate decisions during early human developmentMirjam Verbeek The Francis Crick Institute UKNot available on demand11 30 12 00The kynurenine pathway a metabolic link between maternal obesity and offspring phenotypeHeidi Lempradl Van Andel Institute USA12 00 12 15Closing Remarks and poster prize announcements12 15 12 45Packed lunch and departure Practical information Registration fees and abstract submission On site registration fees include admission conference materials meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Virtual registration fees include access to all of the talks livestreamed and on demand and facility to submit questions On site Academia 550On site PhD Student 385On site Industry 770On site Journal Editors 300Virtual Academia 200Virtual PhD Student 150Virtual Industry 275 Editors from scientific journals are allowed to attend at a reduced rate but asked to contribute to the conference in return by taking part in meet the editors sessions or other planned activities within the programme A letter to support your visa application will be issued on request once payment of the registration fee is confirmed We recommend that you book your visa appointment as soon as possible to avoid any delay with your visa application Accredited journalists may be eligible to register for complimentary press registration Registrants may be required to provide accreditation or equivalent proof of press membership after registration Please contact Nathalie Sneider for more information Please note that we do not offer complimentary registrations for editors of scientific journals Confirmation and payment Registration will be on a first come first served basis Your place can only be confirmed after payment of the registration fee If you are added to our waiting list please consider taking advantage of our offerings to participate virtually On site participants Types of payments accepted are international bank transfers and credit card payments Virtual participants We are only able to accept card payments In exceptional cases we can accept bank transfers Please contact events embl de for details Abstract submission Only participants registering to attend the on site event are eligible to submit an abstract Abstracts will not be accepted from virtual participants After registration you can submit your abstract via a separate link that will be provided in the email confirmation Alternatively you can access the link on the confirmation page directly after registering The same login credentials are used for both processes Please note Abstract body The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised Title The title should not exceed 20 words Only the first word of the title should start with a capital letter and the rest should be lowercase Authors and affiliations Please fill in the author s details as requested in the online form The compulsory fields are First Name Last Name Organisation Name Affiliation or Company Country and Email Kindly mark only one author in the role of First Author and please don t forget to indicate who will be the Presenter Please enter your co authors correctly via the system by adding accounts together with their organisation institute Do not copy paste them into the body of the abstract text as they will not be indexed in the abstract book Presentation types When submitting your abstract you can apply for an oral or poster presentation A selection process will take place with the results announced 2 3 weeks after the abstract submission deadline For detailed instructions on how to submit a conference abstract follow the instructions provided in this video Please check our FAQs pages for further information on how to submit an abstract Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of registration fee waivers travel grants and childcare grants Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course or conference Travel grant The travel grant will cover the cost of travel to an on site event airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from within Europe up to 1000 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from outside Europe up to 500 for any participant travelling to an EMBO Workshop up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Workshop Registration fees are only covered for EMBO Workshops The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant There is the possibility to apply for a childcare grant to offset child care costs incurred by participants speakers and organisers when attending a conference Eligible costs include but are not limited to fees for a baby sitter or child care facility and travel costs for a caregiver Please note that priority will be given to early stage researchers In order to apply for this grant you must be registered by the abstract submission deadline There is a limited amount of funding available for the childcare grants and funds will be distributed amongst eligible applicants Application On site participants You may apply for financial assistance when submitting your abstract In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Virtual participants If you are attending virtually you can apply for financial assistance in the submission portal by the abstract deadline Read the instructions on how to apply for financial assistance Only submissions for financial assistance will be accepted Presentation abstracts cannot be submitted here and will be declined In your application you will be asked to summarise your current work answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Selection The scientific organisers will select the recipients of registration fee waivers and travel grants during the motivation letter or abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection for registration fee waivers and travel grants is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Childcare grants will be allocated in the same timeframe 6 8 weeks before the event start date Please note that priority will be given to early stage researchers Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details View our list of external funding opportunities and information on attending a conference as an event reporter For further information about financial assistance please refer to the FAQ page Accommodation and travel Accommodation is not included in the conference registration fee The hotels below have rooms on hold for participants until Friday 8 August 2025 in some cases at special rates Please email the hotel directly quoting the booking code DMB25 01 to confirm the exact price of the room Hotel AnlageHotel ibis HeidelbergPremier Inn Heidelberg CityB B HotelISG Hotel Staycity Aparthotel HeidelbergExzellenz HotelLeonardo Hotel Heidelberg City CentreSteffi s Hostel HeidelbergHilton HeidelbergMeininger Heidelberg Travel information For travel information please see here If you are travelling to the conference within Germany then you are eligible for the Deutsche Bahn Event Ticket called the Veranstaltungsticket in German This will result in a lower ticket price if your travel distance to Heidelberg is more than 100 km You need to provide proof of your event attendance when purchasing the ticket For more information in English see here or in German see here You can book your ticket here Conference shuttle buses Conference shuttle buses are free of charge for participants and depart from designated bus stops near the hotels to EMBL and back mornings and evenings The bus schedule is available here The bus stops for this conference are Staycity Aparthotel Speyerer Str 7 Kurf rsten Anlage Opposite Main Train Station Premier Inn City Zentrum Kurf rsten Anlage 23 Leonardo Hotel Heidelberg City Center Bergheimer Str 63 Neckarm nzplatz Heidelberg Tourist Information Peterskirche Bus stop Hans B ckler Stra e Bus stop Rohrbacher Str 22 ISG Hotel Im Eichwald 19 View Conference shuttle bus stops and hotels in a larger map Please note that not every bus stop will be used for every event Further details Address EMBL Meyerhofstra e 1 69117 Heidelberg Germany For more information about accommodation and travel please refer to the FAQ page On site information Catering All meals and coffee breaks are included in the registration fee Our catering staff will prepare a wide variety of vegetarian meals meat and fish dishes soups pasta fresh fruit and vegetables as well as a variety of desserts Please wear your badge at all times when serving yourself No food or drinks are allowed in the auditorium Charging lockers There are lockers available next to the stairs leading down into the Auditorium You will find some of those equipped with sockets to charge your smartphone tablet etc Electricity and charging station In most places the electricity is 220 volts AC 50 cycles An adaptor and a plug that fits the German socket may be needed for your appliances laptop i e American Japanese etc A USB charging station for electronic devices is available at the registration desk EMBL merchandise If you are interested in purchasing EMBL merchandise products presented in the glass display in the registration area please email the EMBL shop to place an order or get in contact with your Course Organiser Kindly note the EMBL shop is only open upon request and all purchases must be made in cash Euros only Health and safety notes Please read EMBL s COVID 19 safety policy for on site events Do not smoke in any EMBL building Eating and drinking is prohibited in the Auditorium and all laboratories Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required The first aid room is located next to the ATC Registration Desk room 10 205 Dial the Emergency number 222 from any EMBL internal phone only Where is the accident What happened How many injured Emergency number 06221 387 7821 from mobile phones Please report all accidents to the conference officer at the registration desk In case of fire Press the nearest fire alarm button or the Emergency number 222 from any internal phone A loud fire alarm will go off if an evacuation is required On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting points Do not use the lifts Beyond first aid Please remember to bring your own medication if needed to the conference Note that the next pharmacy is a 4 minute drive from the EMBL but for many medications you will be required to see a doctor to get a prescription Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg In any case the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary Internet Wi Fi is available on campus using the EMBL Events network and the event specific password which will be provided on site The eduroam network secure worldwide roaming access service developed for the international research and education community is also available Lost and found Lost and Found items are kept at the registration desk until the end of the conference Luggage There are lockers available on site to store your luggage which require a 2 EURO coin to operate There is another luggage room on level E0 which is free to use but remains unlocked during the conference Nursing room There is a nursing room available in the ATC Rooftop Lounge on level A29 Photography During the conference an EMBL Photographer may be taking photos If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Printing We can help to print your boarding pass train ticket Please send it to events embl de and collect your print outs at the registration desk Room for prayer yoga and meditation There is a room for prayer meditation and yoga located on level E0 behind the Auditorium Please be respectful of others using the room Sightseeing A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing Travel to and from the venue During the event we provide conference shuttle buses to and from EMBL In addition there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time Information on the conference shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page Useful German expressions HelloHalloGoodbyeAuf Wiedersehen formal Tsch ss informal Good morningGuten MorgenGood afternoonGuten TagGood eveningGuten AbendGood nightGute NachtI m sorryEs tut mir leidExcuse me Entschuldigen SieHow are you Wie gehts I m fine thanks And you Mir geht es gut danke Und Dir Ihnen What is your nameWie hei en Sie formal Wie hei t Du informal My name isIch hei e Do you speak EnglishSprechen Sie englisch I don t understandIch verstehe nichtPlease speak more slowlyK nnen Sie bitte langsamer sprechenThank youDankesch nWhere is the toilet Wo ist die Toilette Please call me a taxiBitte rufen Sie mir ein TaxiHow do I get to Wie komme ich zum zur A beer two beers pleaseEin Bier zwei Bier bitteA glass of red white wine pleaseEin Glas Rot Weisswein bitteThe menu pleaseDie Speisekarte bitteIs there a local speciality Gibt es eine Spezialit t aus dieser Gegend I m vegetarianIch bin VegetarierIt was deliciousEs war hervorragendThe bill pleaseDie Rechnung bitteI have a headacheIch habe KopfschmerzenI have a sore throatIch habe HalsschmerzenMy stomach hurtsIch habe MagenschmerzenI m allergic toIch bin allergisch gegenI need a doctor who speaks EnglishIch brauche einen Arzt der englisch spricht Virtual participation What s included Access to all the livestreamed talks Video library of the recorded talks during the event and for 4 weeks afterwards Please note at the request of individual speakers some talks are not recorded Facility to submit questions Please note that only on site participants are able to submit abstracts and participate in the poster sessions Event platform We are using an event platform for this conference More information about the platform will be shared ahead of the conference Guidelines Do not broadcast the conference to unregistered participants You are encouraged to tweet and post about the event Tweet unless the speaker specifically says otherwise but be mindful of unpublished data Please do not capture transmit or redistribute data presented at the meeting Additional information can be found in our Code of Conduct Health and well being It is important to stay healthy and move around especially when you are attending an event virtually We have put together a few coffee break stretches and yoga videos in the conference platform for you to enjoy during the event How to ask questions Please use the Q A function in the event platform If you have any other questions you can go to the Help Desk in the event platform Click on more on the top menu and click Help Desk Time zone The programme is planned based on the Europe Berlin time zone unless otherwise stated Please take your time zone into consideration when planning your attendance Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for participants page Sponsors Event sponsor Van Andel Institute Media partners Ageing and Cancer Research Treatment ACRT a Science Exploration Press journal ChemBioChem a Wiley journal Development The Company of Biologists journal International Union of Biochemistry and Molecular Biology Medinformatics a Bon View Publishing journal Open Biology a Royal Society journal PLOS Biology a PLOS journal The EMBO Journal an EMBO Press journal Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information on sponsoring possibilities If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9 Leaderboard 728 90...

Alexander Aulehla, Heather Christofk, Heidi Lempradl, Jonathan Rodenfels

EMBO Workshop

EMBL Heidelberg, Virtual

Edit

July 30, 2025 14:002025WebinarVirtual

Description Modern biological research generates vast amounts of data that require complex computational workflows to process efficiently and reproducibly As data volumes continue to grow so does the demand for computing infrastructure to process them Deploying these workflows in the cloud is becoming increasingly common This webinar will introduce the fundamental concepts of cloud deployment for Nextflow pipelines and demonstrate the steps required for setting up a fully functional pipeline in the cloud We will begin by describing the purpose of Workflow Management Systems such as Nextflow and why they have become indispensable in modern computational biology The session will cover both the benefits and potential limitations of cloud based workflow execution helping you understand when and why to leverage cloud resources for your computational workloads We will use the Biome specific Shallow shotgun Inference of Functional Traits through Read mapping BioSIFTR pipeline as our case study This pipeline developed by the Microbiome Informatics team at EMBL EBI as part of the Finding Pheno project serves as an excellent example of a complex computational workflow on a public cloud platform using Nextflow...

Virtual

15 July - 18 July 2025

Gene regulation: one molecule at a time

Edit

July 15, 2025 00:002025ConferenceEMBL Heidelberg, Virtual

Description OverviewSpeakersProgrammeFocus panel discussionsPractical informationSponsorsMedia kit Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Conference overview Gene expression is controlled by the dynamic action of dozens of macromolecular complexes that assemble on DNA to transcribe genes and translate mRNAs to proteins Understanding of these mechanisms has historically been driven by biochemical and structural characterisation of the players as well as probing their function through genetic deletions The genomics revolution has provided us with a near comprehensive picture of where these factors bind to regulate the genome and which transcripts are processed in various biological contexts A key limitation of the resulting models is that they are derived using data that are static by nature unfaithfully representing the dynamics of these regulatory processes in vivo The last few years has seen the independent emergence of microscopy and genomics technologies to monitor gene regulation processes with single molecule resolution Recording the dynamic function of regulatory proteins on DNA and RNA now opens opportunities to understand key parameters of the process such as its kinetics or how various activities are combined in vivo This meeting will bring together pioneers of the single molecule microscopy and single molecule genomics field as well as theoretical biologists to catalyze the emergence of a new generation of mechanistic models of the regulation of genes across each steps of the central dogma Session topics RNA processing Translation Transcription and chromatin regulation Method development Theory Speakers Speakers Nicolas Altemose Stanford University USA Edouard Bertrand Institute of Human Genetics France Lacra Bintu Stanford University USA Hinrich Boeger University of California Santa Cruz USA Jeff Chao Friedrich Miescher Institute for Biomedical Research Switzerland Shasha Chong Caltech USA Stirling Churchman Harvard Medical School USA Ibrahim Ciss Max Planck Institute of Immunobiology and Epigenetics Germany Olga Dudko University of California San Diego USA William Greenleaf Stanford University USA Val rie Hilgers Max Planck Institute of Immunobiology and Epigenetics Germany Mounia Lagha Institut de G n tique Mol culaire de Montpellier France Tineke Lenstra Netherlands Cancer Institute The Netherlands Kazuhiro Maeshima National Institute of Genetics Japan Vijay Ramani University of California San Francisco USA Efrat Shema Weizmann Institute of Science Israel Andrew B Stergachis University of Washington USA Scientific organisers Stirling Churchman Harvard Medical School USA Arnaud Krebs EMBL Heidelberg Germany Mounia Lagha Institut de G n tique Mol culaire de Montpellier France Dan Larson National Cancer Institute Center for Cancer Research USA Conference organiser Inna B sselmann EMBL Heidelberg Germany Programme Are you on social media Post using EMBLSingleMolecule and don t forget to tag EMBLEvents Please note that the programme is subject to change Some speakers may need to join virtually to give their talk For registered participants recorded talks will be accessible on demand for 4 weeks after the end of the event unless indicated otherwise You can find the conference shuttle timetable here Day 1 Tuesday 15 July 2025 Time Europe Berlin Speaker12 30 14 00Registration and light refreshments14 00 14 15Opening remarks by scientific organisers14 15 17 20Session 1Chairs Stirling Churchman Daniel Larson14 15 14 35Super resolution imaging of transcription in living cellsIbrahim Cisse Max Planck Institute of Immunobiology and Epigenetics Germany14 35 14 55Breaking reversibility in eukaryotic gene regulation enhancing activator specificity via energy couplingHinrich Boeger University of California Santa Cruz USA14 55 15 15Elucidating the role of localized translation in circadian clock biology one molecule at a timeIlan Davis University of Glasgow United Kingdom15 15 15 35MYC modulates TOP2A diffusion to promote substrate detection and activity Kathryn Jackson Karolinska Institutet Sweden15 35 16 00Coffee break Meet the speakers and exhibitors16 00 16 20Imaging the life and death of mRNAs in single cellsJeff Chao Friedrich Miescher Institute for Biomedical Research Switzerlan16 20 16 40Probing the regulation of long neuronal RNAs one molecule at a timeValerie Hilgers Max Planck Institute of Immunobiology and Epigenetics GermanyNot available on demand16 40 17 00Molecular co accessibility identifies coordinated regulation between distant cis regulatory elementsKasit Chatsirisupachai EMBL Heidelberg Germany17 00 17 20Lighting up the central dogma to dissect how sharp developmental patterns are establishedMounia Lagha Institut de G n tique Mol culaire de Montpellier France17 20 18 20Speed networking in ATC Foyer18 20 20 00Dinner in EMBL Canteen20 00 22 00After dinner drinks in ATC rooftop lounge Day 2 Wednesday 16 July 2025 Time Europe Berlin Speaker09 00 11 50Session 2Chairs Mounia Lagha Arnaud Krebs09 00 09 20Replication dependent histone Repli Histo labeling dissects the physical properties of euchromatin and heterochromatin in living human cellsKazuhiro Maeshima National Institute of Genetics Japan09 20 09 40Human RNA Polymerase II is maintained in excess for robust transcriptional homeostasis Alexander Gillis University of New South Wales Australia09 40 10 00Incoherent transcription factor action leads to non monotonicity and affinity dependent activation or repression Rosa Martinez Corral Centre for Genomic Regulation Spain10 00 10 30Coffee break Meet the speakers and exhibitors10 30 10 50Analysis of single chromatin fibers reveals that a dynamic ensemble of chromatin structures underlies mitotically heritable transcriptional states Djem Kissiov University of California Berkeley USA10 50 11 10The 3D gene structure of transcriptionally distinct fly brain cell types involves complex changes in promoter proximity to both cis regulatory and non canonical elements Marcelo Nollmann Center of Structural Biology CNRS FranceNot available on demand11 10 11 30PRC1 condensate properties alter outcome of competition with SWI SNF Stefan Niekamp Harvard Medical School USA11 30 11 50Single molecule epigenetics Decoding the epigenome for cancer research and diagnosticsEfrat Shema Weizmann Institute IsraelNot available on demand11 50 13 50Lunch with guided walk in the woods13 50 16 50Session 3Chairs Kazuhiro Maeshima Vijay Ramani13 50 14 10Direct observation of transcription factor association and dissociation dynamics at an endogenous locus in living cellsTineke Lenstra Netherlands Cancer Institute Netherlands14 10 14 30Sequence dependent condensation of pioneer transcription factors on DNA Sina Wittmann Institute of Molecular Biology Germany14 30 14 50Dark proteome mediated transcriptional control in cancer at single molecule resolutionShasha Chong Caltech USAvirtual talkNot available on demand14 50 15 20Coffee break and meet the speakers15 20 15 40Measuring transcriptional repressor binding and gene silencing dynamics using single molecule footprinting Carolina Rios Stanford University USA15 40 16 00What phase s of matter is the chromosomeOlga K Dudko University of California San Diego USANot available on demand16 00 16 20Quantifying the physical genome with single moleculesWilliam Greenleaf Stanford University USA16 20 17 00Flash talk session 1 49 Adam Cawte University of Oxford UK 59 Danilo Dubocanin Stanford University USA 79 Michela Palamin EMBL Heidelberg Germany 91 Elliott Swanson University of Washington USA17 00 18 50Poster session 1 odd numbers in Helix A18 50 20 20Dinner in EMBL Canteen20 20Free evening with option of informal networking in downtown Heidelberg Day 3 Thursday 17 July 2025 Time Europe Berlin Speaker09 00 11 50Session 4Chairs Ibrahim Ciss Val rie Hilgers09 00 09 20A single cell and haplotype resolved view of normal and pathogenic gene regulationAndrew Stergachis University of Washington USA09 20 09 40Fast scanning slow binding DNA shape as a modulator in transcription factor recognition kinetics Elena Rogoulenko Weizmann Institute of Science Israel09 40 10 00A promoter proximal pausing and nuclear speckle interface for RNA processing mediated by TFIIS Andreas Mayer Max Planck Institute for Molecular Genetics GermanyNot available on demand10 00 10 30Coffee break Meet the speakers and exhibitors10 30 10 50Decoding Gene Regulation at the Single Molecule Level through Biophysical Modeling of DNA Footprinting Data Nacho Molina Institute of Genetics and Molecular and Cellular Biology France10 50 11 10Decoding YAP dynamics through charge mediated co condensates Kirstin Meyer Yale University USAvirtual talkNot available on demand11 10 11 30Single Molecule DNA Footprinting and Transcription Imaging Reveal the Molecular Mechanisms of Promoter DynamicsEdouard Bertrand Institute of Human Genetics France11 30 11 50Single cell chromatin changes associated with silencing and epigenetic memoryLacra Bintu Stanford University USA11 50 14 00Lunch and focus panel discussions 13 00 13 45Panel 1 Single molecule genomics data analysis Chair Stirling ChurchmanHelix A Seminar room 01 Panel 2 Single molecule microscopy data analysis Chairs Dan Larson Mounia LaghaKlaus Tschira Auditorium14 00 16 40Session 5Chairs Lacra Bintu Marcelo Nollmann14 00 14 20Long read single molecule sequencing methods for studying protein DNA interactions and 3D chromatin architectureNicolas Altemose Stanford University USA14 20 14 40Chromatin dynamics across seven orders of magnitude Matteo Mazzocca Massachusetts Institute of Technology USA14 40 15 00Live cell single molecule DNA binding kinetics and energetics of TFsChristof Gebhardt Ulm University GermanyNot available on demand15 00 15 30Coffee break Meet the editors15 30 15 50Super resolution imaging of mRNA reveals translation dependent alterations to mRNA structure in vivo Murali Palangat National Cancer Institute National Institutes of Health USANot available on demand15 50 16 00Flash talk session 2 82 Marco Payr EMBL Heidelberg Germany16 00 18 00Poster session 2 even numbers 18 00 20 00Conference dinner in the EMBL Canteen20 00 00 00Conference party at the Rooftop Lounge Day 4 Friday 18 July 2025 Time Europe Berlin Speaker09 30 12 15Session 6Chairs Andrew Stergachis Tineke Lenstra09 30 09 50Pervasive programmed and patterned nucleosomal distortion is a hallmark of mammalian chromatin fibersVijay Ramani University of California San Francisco USA09 50 10 10Live single transcript imaging reveals a global shift in particle dynamics during neuronal development Franka Voigt University of Z rich SwitzerlandNot available on demand10 10 10 30Revealing Chromatin Architectures Across Cellular Compartments by Fiber seqStirling Churchman Harvard University USA10 30 11 00Coffee break Meet the speakers and exhibitors11 00 11 20Deep coverage whole genome adenine footprinting unmasks hidden chromatin features Michael B Stadler University of Basel Switzerland11 20 11 40Nanog stabilizes Nanog DNA clusters to facilitate transcription Nadine Vastenhouw University of Lausanne Switzerland11 40 12 00Coordination of eRNA and mRNA in living cells at the MYC locusDaniel Larson National Cancer Institute Center for Cancer Research USA12 00 12 15Closing remarks and poster prize announcements12 15 12 30Packed lunch and departure12 30Bus shuttle to Frankfurt am Main airport12 45Bus shuttle to the main station Focus panel discussions Thursday 17 July 2025 13 00 13 45 pm Panel 1 Single molecule genomics data analysis Room Helix A Seminar room 01 Only 30 seats available first come first served Chairs Stirling Churchman Single molecule genomics data analysis represents an evolving field with diverse analytical approaches Analysis encompasses multiple computational strategies from sequence alignment and modification detection algorithms to statistical frameworks for identifying protein DNA interactions and chromatin states These methodologies have been tailored for specific experimental systems and sequencing platforms The goal of this workshop is to explore various analytical approaches followed by in depth discussions on strategy optimization across different genome scales and sequencing technologies Panel 2 Single molecule microscopy data analysis Room Klaus Tschira Auditorium Chairs Dan Larson Mounia LaghaSingle molecule microscopy data analysis is a mature yet highly idiosyncratic field Analysis relies on a host of techniques ranging from microscopy based algorithms for identification segmentation and tracking to advanced statistical inference methods for model selection and parameter estimation These approaches have been adapted and optimized for particular biological systems and imaging strategies The goal of this workshop is to provide participants with a technical overview with ample time for discussion Practical information Registration fees and abstract submission On site registration fees include admission conference materials meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Virtual registration fees include access to all of the talks livestreamed and on demand and facility to submit questions On site Academia 800On site PhD Student 700On site Industry 1000On site Journal Editors 300Virtual Academia 225Virtual PhD Student 175Virtual Industry 275 Editors from scientific journals are allowed to attend at a reduced rate but asked to contribute to the conference in return by taking part in meet the editors sessions or other planned activities within the programme A letter to support your visa application will be issued on request once payment of the registration fee is confirmed We recommend that you book your visa appointment as soon as possible to avoid any delay with your visa application Accredited journalists may be eligible to register for complimentary press registration Registrants may be required to provide accreditation or equivalent proof of press membership after registration Please contact Inna B sselmann for more information Please note that we do not offer complimentary registrations for editors of scientific journals Confirmation and payment Registration will be on a first come first served basis Your place can only be confirmed after payment of the registration fee If you are added to our waiting list please consider taking advantage of our offerings to participate virtually On site participants Types of payments accepted are international bank transfers and credit card payments Virtual participants We are only able to accept card payments In exceptional cases we can accept bank transfers Please contact events embl de for details Abstract submission Only participants registering to attend the on site event are eligible to submit an abstract Abstracts will not be accepted from virtual participants After registration you can submit your abstract via a separate link that will be provided in the email confirmation Alternatively you can access the link on the confirmation page directly after registering The same login credentials are used for both processes Please note Abstract body The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised Title The title should not exceed 20 words Only the first word of the title should start with a capital letter and the rest should be lowercase Authors and affiliations Please fill in the author s details as requested in the online form The compulsory fields are First Name Last Name Organisation Name Affiliation or Company Country and Email Kindly mark only one author in the role of First Author and please don t forget to indicate who will be the Presenter Please enter your co authors correctly via the system by adding accounts together with their organisation institute Do not copy paste them into the body of the abstract text as they will not be indexed in the abstract book Presentation types When submitting your abstract you can apply for an oral or poster presentation A selection process will take place with the results announced 2 3 weeks after the abstract submission deadline For detailed instructions on how to submit a conference abstract follow the instructions provided in this video Please check our FAQs pages for further information on how to submit an abstract Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of registration fee waivers travel grants and childcare grants Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course or conference Travel grant The travel grant will cover the cost of travel to an on site event airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from within Europe up to 1000 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from outside Europe up to 500 for any participant travelling to an EMBO Workshop up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Workshop up to 700 for any participant working in Croatia Czech Republic Estonia Greece Hungary Italy Lithuania Luxembourg Poland Slovenia and Turkey travelling to an EMBO Workshop Registration fees are only covered for EMBO Workshops The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant There is the possibility to apply for a childcare grant to offset child care costs incurred by participants speakers and organisers when attending a conference Eligible costs include but are not limited to fees for a baby sitter or child care facility and travel costs for a caregiver Please note that priority will be given to early stage researchers In order to apply for this grant you must be registered by the abstract submission deadline There is a limited amount of funding available for the childcare grants and funds will be distributed amongst eligible applicants Application On site participants You may apply for financial assistance when submitting your abstract In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Virtual participants If you are attending virtually you can apply for financial assistance in the submission portal by the abstract deadline Read the instructions on how to apply for financial assistance Only submissions for financial assistance will be accepted Presentation abstracts cannot be submitted here and will be declined In your application you will be asked to summarise your current work answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Selection The scientific organisers will select the recipients of registration fee waivers and travel grants during the motivation letter or abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection for registration fee waivers and travel grants is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Childcare grants will be allocated in the same timeframe 6 8 weeks before the event start date Please note that priority will be given to early stage researchers Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details View our list of external funding opportunities and information on attending a conference as an event reporter For further information about financial assistance please refer to the FAQ page Accommodation and travel Accommodation is not included in the conference registration fee The hotels below have rooms on hold for participants until 17 June 2025 in some cases at special rates Please email the hotel directly quoting the booking code GRG25 01 to confirm the exact price of the room Hotel AnlageHotel Holl nder Hof Hotel MonptiHotel Bayrischer Hof Hotel ibis HeidelbergPremier Inn Heidelberg City ZentrumB B HotelISG Hotel Staycity Aparthotel HeidelbergThe Heidelberg Exzellenz HotelLeonardo Hotel Heidelberg City CentreSteffi s Hostel HeidelbergHilton HeidelbergMeininger HeidelbergHotel Vier Jahreszeiten Heidelberg Travel information For travel information please see here If you are travelling to the conference within Germany then you are eligible for the Deutsche Bahn Event Ticket called the Veranstaltungsticket in German This will result in a lower ticket price if your travel distance to Heidelberg is more than 100 km You need to provide proof of your event attendance when purchasing the ticket For more information in English see here or in German see here You can book your ticket here Conference shuttle buses Conference shuttle buses are free of charge for participants and depart from designated bus stops near the hotels to EMBL and back mornings and evenings The bus stops for this conference are Staycity Aparthotel Speyerer Str 7 Kurf rsten Anlage Opposite Main Train Station Premier Inn City Zentrum Kurf rsten Anlage 23 Leonardo Hotel Heidelberg City Center Bergheimer Str 63 Neckarm nzplatz Heidelberg Tourist Information Peterskirche Bus stop Hilton Hotel Kurf rsten Anlage 1 ISG Hotel Im Eichwald 19 View Conference shuttle bus stops and hotels in a larger map Please note that not every bus stop will be used for every event Further details Address EMBL Meyerhofstra e 1 69117 Heidelberg Germany For more information about accommodation and travel please refer to the FAQ page On site information Catering All meals and coffee breaks are included in the registration fee Our catering staff will prepare a wide variety of vegetarian meals meat and fish dishes soups pasta fresh fruit and vegetables as well as a variety of desserts Please wear your badge at all times when serving yourself No food or drinks are allowed in the auditorium Charging lockers There are lockers available next to the stairs leading down into the Auditorium You will find some of those equipped with sockets to charge your smartphone tablet etc Electricity and charging station In most places the electricity is 220 volts AC 50 cycles An adaptor and a plug that fits the German socket may be needed for your appliances laptop i e American Japanese etc A USB charging station for electronic devices is available at the registration desk EMBL merchandise If you are interested in purchasing EMBL merchandise products presented in the glass display in the registration area please email the EMBL shop to place an order or get in contact with your Course Organiser Kindly note the EMBL shop is only open upon request and all purchases must be made in cash Euros only Health and safety notes Please read EMBL s COVID 19 safety policy for on site events Do not smoke in any EMBL building Eating and drinking is prohibited in the Auditorium and all laboratories Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required The first aid room is located next to the ATC Registration Desk room 10 205 Dial the Emergency number 222 from any EMBL internal phone only Where is the accident What happened How many injured Emergency number 06221 387 7821 from mobile phones Please report all accidents to the conference officer at the registration desk In case of fire Press the nearest fire alarm button or the Emergency number 222 from any internal phone A loud fire alarm will go off if an evacuation is required On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting points Do not use the lifts Beyond first aid Please remember to bring your own medication if needed to the conference Note that the next pharmacy is a 4 minute drive from the EMBL but for many medications you will be required to see a doctor to get a prescription Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg In any case the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary Internet Wi Fi is available on campus using the EMBL Events network and the event specific password which will be provided on site The eduroam network secure worldwide roaming access service developed for the international research and education community is also available Lost and found Lost and Found items are kept at the registration desk until the end of the conference Luggage There are lockers available on site to store your luggage which require a 2 EURO coin to operate There is another luggage room on level E0 which is free to use but remains unlocked during the conference Nursing room There is a nursing room available in the ATC Rooftop Lounge on level A29 Photography During the conference an EMBL Photographer may be taking photos If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Printing We can help to print your boarding pass train ticket Please send it to events embl de and collect your print outs at the registration desk Room for prayer yoga and meditation There is a room for prayer meditation and yoga located on level E0 behind the Auditorium Please be respectful of others using the room Sightseeing A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing Travel to and from the venue During the event we provide conference shuttle buses to and from EMBL In addition there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time Information on the conference shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page Useful German expressions HelloHalloGoodbyeAuf Wiedersehen formal Tsch ss informal Good morningGuten MorgenGood afternoonGuten TagGood eveningGuten AbendGood nightGute NachtI m sorryEs tut mir leidExcuse me Entschuldigen SieHow are you Wie gehts I m fine thanks And you Mir geht es gut danke Und Dir Ihnen What is your nameWie hei en Sie formal Wie hei t Du informal My name isIch hei e Do you speak EnglishSprechen Sie englisch I don t understandIch verstehe nichtPlease speak more slowlyK nnen Sie bitte langsamer sprechenThank youDankesch nWhere is the toilet Wo ist die Toilette Please call me a taxiBitte rufen Sie mir ein TaxiHow do I get to Wie komme ich zum zur A beer two beers pleaseEin Bier zwei Bier bitteA glass of red white wine pleaseEin Glas Rot Weisswein bitteThe menu pleaseDie Speisekarte bitteIs there a local speciality Gibt es eine Spezialit t aus dieser Gegend I m vegetarianIch bin VegetarierIt was deliciousEs war hervorragendThe bill pleaseDie Rechnung bitteI have a headacheIch habe KopfschmerzenI have a sore throatIch habe HalsschmerzenMy stomach hurtsIch habe MagenschmerzenI m allergic toIch bin allergisch gegenI need a doctor who speaks EnglishIch brauche einen Arzt der englisch spricht Virtual participation What s included Access to all the livestreamed talks Video library of the recorded talks during the event and for 4 weeks afterwards Please note at the request of individual speakers some talks are not recorded Facility to submit questions Please note that only on site participants are able to submit abstracts and participate in the poster sessions Event platform We are using an event platform for this conference More information about the platform will be shared ahead of the conference Guidelines Do not broadcast the conference to unregistered participants You are encouraged to tweet and post about the event Tweet unless the speaker specifically says otherwise but be mindful of unpublished data Please do not capture transmit or redistribute data presented at the meeting Additional information can be found in our Code of Conduct Health and well being It is important to stay healthy and move around especially when you are attending an event virtually We have put together a few coffee break stretches and yoga videos in the conference platform for you to enjoy during the event How to ask questions Please use the Q A function in the event platform If you have any other questions you can go to the Help Desk in the event platform Click on more on the top menu and click Help Desk Time zone The programme is planned based on the Europe Berlin time zone unless otherwise stated Please take your time zone into consideration when planning your attendance Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for participants page COVID 19 related questions COVID 19 information for on site events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Bronze sponsor Event sponsorsNew England Biolabs Proteintech Media partners ChemBioChem a Wiley journal EMBO Reports an EMBO Press journal International Union of Biochemistry and Molecular Biology Medinformatics a Bon View Publishing journal Open Biology a Royal Society journal Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information on sponsoring possibilities If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de Media kit Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9 Leaderboard 728 90...

Stirling Churchman, Arnaud Krebs, Mounia Lagha, Daniel Larson

EMBL Conference

EMBL Heidelberg, Virtual

14 July - 18 July 2025

Fluorescence imaging beyond intensity

Edit

July 14, 2025 00:002025CourseEMBL Heidelberg

Open FAIR data: the role of public data archives

Edit

June 25, 2025 14:302025WebinarVirtual

Description Scientific progress relies on open FAIR data Describing datasets with rich metadata and appropriate standards and submitting these to public archives is crucial in linking different data types in an open accessible and sustainable manner This webinar will introduce two public archives BioSamples and BioImage Archive After a brief overview we will provide information on how you can use these repositories to make your data open and FAIR with a particular focus on complex multi modal datasets Please note that by clicking on Access Materials a pptx file with the slides of the presentation will be automatically downloaded...

Virtual

Edit

June 16, 2025 00:002025CourseEMBL-EBI

Description This course will introduce life scientists to practical data science topics used in life sciences such as data handling and visualisation statistical analysis application of AI and use of publicly available databases You will initially be introduced to data science theory and practice including best practices for undertaking analyses data management and reproducibility The course will provide hands on training in tools and resources appropriate to your research including introducing the use of Python for handling and visualising data statistical analysis and the application of machine learning Group projectsThis course includes group projects where you will be placed in small groups to work together on a challenge set by trainers from EMBL EBI This allows you to explore the data sciences methods and resources you will learn about during the course and apply them to a set problem providing you with hands on experience The group work will culminate in a flash talk session involving everyone on the final day of the course Groups are mentored and supported by the trainers who set the initial challenge but the groups will be responsible for driving their projects forward with all members expected to take an active role There are two different group project topics gene expression and protein structure Both these projects will provide an opportunity for participants to apply the knowledge and skills learnt during the other sessions of the course including data handling in Python data visualisation statistics and machine learning The projects will also allow participants to gain experience of using EMBL EBI data resources including Expression Atlas and the Single Cell Expression Atlas for the gene expression project and the resources PDBe and AlphaFold for the protein structures project You will be asked during your application to select the group project topic you would most benefit from The projects cover mammalian data sets however in many cases the methods and approaches taught are transferable to data from various species...

Meredith Willmott

EMBL-EBI

15 June - 20 June 2025

Imaging-based spatial-omics

Edit

June 15, 2025 00:002025CourseEMBL Heidelberg

Description OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview Course overview The aim of the course is to provide participants a comprehensive introduction to the various methods of spatial omics and in particular those of multiplex immunofluorescence and spatial transcriptomics We want to provide a general overview of the methods and assist researchers choose the right method for their needs With hands on practicals the course will teach participants how to carry out open source imaging based methods for cost effective spatial transcriptomics and multiplex immunofluorescence The course will cover all experimental stages including custom reagent preparation sample preparation and data acquisition with various microscopy modalities as well as image processing and basic data analysis Audience This course is open to PhD students postdocs and staff We seek participants from the following backgrounds tissue biology or biomedicine with experience in basic tissue handling immunofluorescence and basic microscopy Modules Resources Tissue sample preparation In situ sequencing Oligo probe design In situ signal amplification Antibody DNA conjugation Multiplexed protein imaging IBEX and Immuno SABER Basic data processing and analysis Learning outcomes Familiarity with spatial omics methods Protocol optimisation Knowhow for imaging based spatial omics workflows Knowledge to choose the most suitable methods for own projects Understanding the data processing and analysis needs What past participants say about the course Incredibly motivating experience packed with great scientific discussions and networking Within just one week we learned how easy it is to replicate some of the daunting spatial techniques in the lab and I cannot wait to bring this knowledge back to my institute Ines Boehm Biozentrum University of Basel Switzerland This event has been granted the following EMBO sustainability badge Grade 2 of 3 Speakers Speakers trainers and staff Omer Bayraktar Wellcome Sanger Institute UK Francesco Bacchi CrestOptics Italy Fabian Coscia Max Delbr ck Center Germany Colin Chu University College London UK Alvaro Crevenna EMBL Rome Italy Yulia Ermakova EMBL Heidelberg Germany Arne Giebeler Nikon Germany Sebastian Gonzalez Heidelberg University Hospital Germany Marco Grillo Stockholm University Sweden Julian Gurgo EMBL Rome Italy Felix Hartmann DKFZ Germany Kristina Jevdokimenko EMBL Heidelberg Germany Marina Peralta EMBL Rome Italy Emerald Perlas EMBL Rome Italy Andrea Radtke Leica Microsystems USA Robert Reinhardt EMBL Heidelberg Germany Sinem Saka EMBL Heidelberg Germany Denis Schapiro Heidelberg University Hospital Germany Oliver Stegle EMBL Heidelberg Germany Caterina Strambio De Castillia University of Massachusetts USA Virtual speaker Xiao Wang Broad Institute MIT and Harvard Cambridge USA Virtual speaker Scientific organisers Alvaro Crevenna EMBL Rome Italy Emerald Perlas EMBL Rome Italy Andrea Radtke Leica Microsystems USA Sinem Saka EMBL Heidelberg Germany Course organisers Iva Gavran Course and Conference Officer EMBL Heidelberg Germany Irena Provaznikova Senior Scientific Training and Digital Learning Manager EMBL Heidelberg Germany Programme Are you on social media Post using EMBOSpatialOmics and don t forget to tag EMBLEvents Some speakers will join virtually to give their lecture or Q A and the programme is subject to change Onboarding day a few days ahead of the course 11 June Day 1 Sunday 15 June 2025 Time Berlin Europe SpeakerLocation13 15 13 30Bus from ISG hotel to EMBL13 30 13 45 Arrival and registration with refreshmentsCourtyard Room A B13 45 13 55House notes and safety rules Alvaro Crevenna EMBL Rome ItalyCourtyard Room A B13 55 14 15Introduction to Responsible conduct of research Alvaro Crevenna EMBL Rome ItalyCourtyard Room A B14 15 15 15Introduction to Spatial omics Sinem Saka EMBL Heidelberg GermanyCourtyard Room A B15 15 16 15Student flash talksCourtyard Room A B16 15 16 30Coffee breakCourtyard Foyer16 30 17 152D and 3D multiplexed imaging using IBEXAndrea Radtke Leica Microsystems and Colin Chu University of College LondonCourtyard Room A B17 15 18 45Tissue sample preparationEMBL Main building18 45 19 30Sample staining for multiplexed antibody imaging IBEX block stainEMBL Main building19 30 19 40Bus from EMBL to ISG hotelATC Entrance19 45 20 45Dinner at ISG hotelISG hotel Day 2 Monday 16 June 2025 Time Berlin Europe SpeakerLocation08 40 08 50Bus from ISG hotel to EMBL08 50 09 00Overview of the dayCourtyard Room A B09 00 09 45Sample staining for multiplexed antibody imaging IBEX wash mount continued Training Lab A B09 45 10 00Coffee breakCourtyard Foyer10 00 11 00Participant presentations I 1 4 Courtyard Room A B11 00 12 00Microscopy Sample Imaging IBEX microscopy cycle 1Microscopy rooms Imaging Centre12 00 13 00Lunch at EMBL CanteenEMBL Canteen13 00 14 00Participant presentations II 5 8 Courtyard Room A B14 00 15 00Sample staining for multiplexed antibody imaging IBEX bleach restain continued Training Lab A B15 00 15 15Coffee breakCourtyard Foyer15 15 16 00Immuno SABER intro and sample preparationTraining Lab A B16 00 16 45Generation of concatemeric signal amplifiersTraining Lab A B16 45 18 45Antibody DNA conjugation With flexible coffee breakTraining Lab A B18 45 19 30Sample staining for multiplexed antibody imaging SABER stain continued Training Lab A B19 30 20 30Pizza dinnerATC Rooftop Lounge20 30 20 40Bus from EMBL to ISG hotel Day 3 Tuesday 17 June 2025 Time Berlin Europe SpeakerLocation08 35 08 45Bus from ISG hotel to EMBL08 45 09 00Overview of the dayCourtyard Room A B09 00 10 15Sample staining for multiplexed antibody imaging SABER wash and concatemer hyb continued Training Lab A B10 15 10 30Coffee break10 30 11 30Participant presentations III 9 12 Courtyard Room A B11 30 12 15Sample staining for multiplexed antibody imaging SABER wash and imager hyb continued Training Lab A B12 15 12 30Group photo 12 30 13 15Lunch at EMBL CanteenEMBL Canteen13 15 15 15Microscopy Sample Imaging Wash mount SABER imaging and restainTraining Lab A B15 15 15 30Coffee break15 30 16 30Participant presentations IV 13 16 Courtyard Room A B16 30 17 30Microscopy Sample Imaging Wash and SABER imagingTraining Lab A B17 30 18 45Oligo padlock probe design ISS intro and probe design With flexible coffee breakTraining Lab A B18 45 19 45In situ sequencing ISS hyb padlockTraining Lab A B19 45 20 45Dinner at EMBL CanteenEMBL Canteen20 45 20 50Bus from EMBL to ISG hotelATC Entrance Day 4 Wednesday 18 June 2025 Time Berlin Europe SpeakerLocation08 40 08 50Bus from ISG hotel to EMBL 08 50 09 00Overview of the dayCourtyard Room A B09 00 10 00In situ sequencing ISS ligation continued Training Lab A B10 00 10 15Coffee breakCourtyard Foyer10 15 11 00Imaging metabolic regulation in human cancerFelix Hartman DKFZ GermanyCourtyard Room A B11 00 12 00In situ sequencing ISS RCA continued Training Lab A B12 00 13 00Lunch at EMBL CanteenEMBL Canteen13 00 13 45Image and data analysis of spatial transcriptomics Marco Grillo Stockholm University SwedenCourtyard Room A B13 45 14 30Mapping cells in space and time Omer Bayraktar Sanger Institute UKVirtual talkCourtyard Room A B14 30 15 00Coffee break Courtyard Foyer15 00 15 40Principles of data management for spatial omics Caterina Strambio De Castillia University of Massachusetts USA Virtual talkCourtyard Room A B15 40 16 10Data frameworks and analysis tools for spatial omics Oliver Stegle EMBL HeidelbergCourtyard Room A B16 15 17 00Bus to city centre with a stop at ISG hotel 17 00 19 15Heidelberg city walking tour and Free time 19 15 21 30Downtown course dinner Day 5 Thursday 19 June 2025 Time Berlin Europe SpeakerLocation09 40 09 50Bus from ISG hotel to EMBL09 50 10 00Overview of the dayCourtyard Room A B10 00 11 00In situ sequencing ISS L probe continued Training Lab A B11 00 11 15Coffee breakCourtyard Foyer11 15 12 00Data analysis for spatial proteomicsDenis Schapiro Heidelberg University GermanyCourtyard Room A B12 00 13 00Lunch at EMBL CanteenEMBL Canteen13 00 14 00In situ sequencing ISS imager continued Training Lab A B14 00 15 00Round table discussion on pitfalls and challenges for the various methodsCourtyard Room A B15 00 15 15Coffee breakCourtyard Foyer15 15 16 30Microscopy Sample Imaging ISS microscopy continued Microscopy rooms16 30 18 00User case discussion with flexible coffee breakATC Rooftop Lounge18 00 19 00Multimodal in situ analysis of single cell transcriptional states Xiao Wang Broad Institute MIT and Harvard USA Virtual talkCourtyard Room A B19 00 20 00Dinner at EMBL CanteenEMBL Canteen20 00 20 10Bus from EMBL to ISG hotelATC Entrance Day 6 Friday 20 June 2025 Time Berlin Europe SpeakerLocation08 40 08 50Bus from ISG hotel to EMBL08 50 09 00Overview of the dayCourtyard Room A B09 00 10 00Data analysis exercises Data processingComputer Training Lab10 00 10 15Coffee breakCourtyard Foyer10 15 11 00Spatial proteomics Fabian Coscia Max Delbruck Center GermanyCourtyard Room A B11 00 12 00Data analysis exercises Visualisation I continued Computer Training Lab12 00 13 00Lunch at EMBL CanteenEMBL Canteen13 00 14 00Data analysis exercises Visualisation II continued Computer Training Lab14 00 14 30Final feedback and summaryCourtyard Room A B14 30 15 00Departure shuttle bus to Heidelberg train station ATC Entrance Practical information Registration fees and motivation letter The course is limited to 16 participants For selection purposes please note that your application will not be considered without a letter of motivation Registration Registration fees include admission and all course materials Academia 500PhD Student 500Industry 1000 Confirmation and payment The registration fee should be paid only after acceptance to the course The results will be announced approximately 2 3 weeks after the application deadline Motivation letter submission After you have logged in and successfully registered you will receive an email asking you to submit your motivation letter Click on the link provided and enter your motivation letter in the text box provided Alternatively you can submit your motivation letter by clicking on the link on the confirmation page directly after registering Instructions Include your relevant skills experience and qualifications showing why you would be suitable for the course Explain why you would like to attend including what you can contribute and how you think you will benefit from the course Please note The limit of 1500 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 1500 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised For detailed instructions please watch our video on how to submit a course motivation letter Further details For further information about registration and motivation letter submission please refer to the FAQ page Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of registration fee waivers and childcare grants Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waivers The fee waiver will cover the registration sum that you have paid to attend the course Childcare grants There is the possibility to apply for a childcare grant to offset child care costs incurred by participants speakers trainers and organisers when attending a course Eligible costs include but are not limited to fees for a babysitter or child care facility and travel costs for a caregiver Please note that priority will be given to early stage researchers There is a limited amount of funding available for the childcare grants and funds will be distributed amongst eligible applicants Boehringer Ingelheim Fonds travel grant Applies to selected courses only Availability will be indicated during the abstract or motivation letter submission process This grant covers costs related to your attendance to the course registration travel and accommodation costs The grant is restricted to PhD students and postdocs who conduct basic biomedical research Whether you are eligible to apply for a travel grant depends on when you received your university entrance qualification e g Abitur A Levels High School Diploma Final State Examination for PhD and MD students as well as graduates the university entrance qualification must not have been obtained more than 11 years ago at the time of the envisaged course for postdocs the university entrance qualification must not have been obtained more than 13 years ago at the time of the envisaged course Application If you are attending virtually you can apply for financial assistance in the submission portal by the abstract deadline Read the instructions on how to apply for financial assistance Only submissions for financial assistance will be accepted Presentation abstracts cannot be submitted here and will be declined In your application you will be asked to summarise your current work answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application For some events applications for Childcare Grants will still be done by email Information about the grant will be sent out shortly after the abstract motivation letter deadline Please contact the event Conference Officer if you have any questions Selection The scientific organisers will select the recipients of registration fee waivers during the participant selection process for courses Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection for registration fee waivers and travel grants is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Childcare grants will be allocated in the same timeframe 6 8 weeks before the event start date Please note that priority will be given to early stage researchers Further details Check out this list of external funding opportunities For further information about financial assistance please refer to the FAQ page Accommodation and travel Hotel Accommodation in twin rooms including breakfast is included in the registration fee Accommodation has been booked for you at the ISG Hotel for the default dates of 15 to 20 June 5 nights In case you would like to have a single room please let the hotel know and please note that you will be required to pay an additional cost of 22 5 per night availability of single rooms may be limited This should be paid by you directly to the ISG during your stay Any additional nights need to be booked and paid for by you We recommend that all course participants stay at the ISG Hotel for the course Travel information For travel information please see here If you are travelling to the conference within Germany then you are eligible for the Deutsche Bahn Event Ticket called the Veranstaltungsticket in German This will result in a lower ticket price if your travel distance to Heidelberg is more than 100 km You need to provide proof of your event attendance when purchasing the ticket For more information in English see here or in German see here You can book your ticket here Local transport Shuttle buses will go from the ISG Hotel to EMBL and back mornings and evenings A bus schedule and location of the bus stops will be made available prior to the meeting Further details Address EMBL Heidelberg Meyerhofstra e 1 69117 Heidelberg Germany For more information about accommodation and travel please refer to the FAQ page On site information Catering All meals and coffee breaks are included in the registration fee Our catering staff will prepare a wide variety of vegetarian meals meat and fish dishes soups pasta fresh fruit and vegetables as well as a variety of desserts Please wear your badge at all times when serving yourself No food or drinks are allowed in the laboratories Electricity and charging station In most places the electricity is 220 volts AC 50 cycles An adaptor and a plug that fits the German socket may be needed for your appliances laptop i e American Japanese etc A USB charging station for electronic devices is available at the registration desk EMBL Merchandise If you are interested in purchasing EMBL merchandise products presented in the glass display in the registration area please email the EMBL shop to place an order or get in contact with your Course Organiser Kindly note the EMBL shop is only open upon request and all purchases must be made in cash Euros only Health and safety notes Please read EMBL s COVID 19 safety policy for on site events Do not smoke in any EMBL building Eating and drinking is prohibited in all laboratories Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required The first aid room is located next to the ATC Registration Desk room 10 205 Dial the Emergency number 222 from any EMBL internal phone only Where is the accident What happened How many injured Emergency number 06221 387 7821 from mobile phones Please report all accidents to the conference officer at the registration desk In case of fire Press the nearest fire alarm button or the Emergency number 222 from any internal phone A loud fire alarm will go off if an evacuation is required On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting points Do not use the lifts Beyond first aid Please remember to bring your own medication if needed to the conference Note that the next pharmacy is a 4 minute drive from the EMBL but for many medications you will be required to see a doctor to get a prescription Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg In any case the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary Internet Wi Fi is available on campus Log in using the EMBL Events network and the event specific password which will be provided on site The eduroam network secure worldwide roaming access service developed for the international research and education community is also available Lost and found Lost and Found items are kept at the registration desk until the end of the conference Luggage There are lockers available on site to store your luggage which require a 2 EURO coin to operate There is another luggage room on level E0 which is free to use but remains unlocked during the conference Nursing room There is a nursing room available in the ATC Rooftop Lounge on level A29 Photography During the conference an EMBL Photographer may be taking photos If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Printing We can help to print your boarding pass train ticket Please send it to events embl de and collect your print outs at the registration desk Room for prayer yoga and meditation There is a room for prayer meditation and yoga located on level E0 behind the Auditorium Please be respectful of others using the room Sightseeing A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing Travel to and from the venue During the event we provide conference shuttle buses to and from EMBL In addition there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time Information on the shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page Map to walk from ISG Hotel to EMBL Technical requirements and event software Technical requirements Below you will find the software and technical requirements for this course You will need admin rights to be able to install the software on your computer and we recommend you try this before the course If you do not have admin rights please contact your technical support team in advance to make sure the software can be installed Additional software The EMBL eCampus learning platform will be used to collaborate communicate and network with all of the course participants All participants will receive information on how to join shortly before the course We recommend using Chrome Safari or Mozilla Firefox browsers for eCampus Additional information Please find additional information including FAQs and terms and conditions on our Information for Participants page Sponsors Event partner Event sponsors Media partners Microcscopy and Analysis a Wiley journal Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other events or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9...

Alvaro Crevenna, Andrea Radtke, Emerald Perlas, Sinem Saka,

EMBO Practical Course

EMBL Heidelberg

14 June - 20 June 2025

Computational modelling of multicellular systems

Edit

June 14, 2025 00:002025CourseEMBL Barcelona

Description OverviewSpeakersProgrammePractical InformationSponsorsMedia kit Overview Course overview This practical course teaches the basics of multicellular modelling to any researcher wishing to enter the field particularly experimentalists with no prior experience of computational modelling It is a hands on course with 60 of the time devoted to students working on laptops performing exercises designed to give a practical familiarity with different types of computational modelling The course focuses on the dynamics of multicellular systems from embryos to organoids covering both the molecular side how gene regulatory networks perform pattern formation and also the mechanical side in 2D and 3D how the movements and activities of many cells together leads to tissue level morphogenesis and organisation A carefully chosen variety of modelling tools will be introduced which cover the core approaches of vertex models finite element models FEM and agent based models ABM Attendees will also work through the week in small groups on group projects which will be presented on the last day to the whole class Each day will end with a keynote lecture by a prominent researcher in the field putting the topic of the day into context through an example of relevant biological research The week is organised to maximise networking between the students and the teachers and speakers This event has been granted the following EMBO sustainability badge Grade 1 of 3 Speakers Speakers trainers staff Katie Bentley The Francis Crick Institute UK James Briscoe The Francis Crick Institute UK Javier Buceta Institute for Integrative Systems Biology I SysBio CSIC UV Spain Jordi Garcia Ojalvo Universitat Pompeu Fabra Spain Yanlan Mao MRC Laboratory for Molecular Cell Biology UK James Sharpe EMBL Barcelona Spain Alejandro Torres Sanchez EMBL Barcelona Spain Berta Verd University of Oxford UK Alexandria Volkening Purdue University USA Scientific organisers Katie Bentley The Francis Crick Institute UK James Sharpe EMBL Barcelona Spain Alejandro Torres Sanchez EMBL Barcelona Spain Event organisers Silvia Autet Balcells Operations Officer EMBL Barcelona Spain Regie Jimena de la Pena Trainee EMBL Barcelona Spain Julia Patricia Nohle Course and Conference Officer EMBL Heidelberg Germany Programme This programme is subject to changes If you are sharing this meeting on social media please use the hashtag EMBOMulticellModelling and don t forget to tag EMBLEvents Day 1 Saturday 14 June 2025 Time Barcelona Europe SpeakerLocation14 00 15 00HousenotesCourse Overview and Meet Greet with welcome Drink nibbles15 00 15 45Bootcamp Lecture 1Why modelling biological systems Basic mathematical concepts that serve to quantify biological processesJames Sharpe EMBL Barcelona SpainSeminar Room Aula de Seminari 15 45 16 45Bootcamp Practical 1main trainer James Sharpe EMBL Barcelona Spain Practical exercises on laptops introduction to programming define a function plot it compute derivatives explore Hill functions Software python codeSeminar Room Aula de Seminari 16 45 17 15Coffee break17 15 18 00Bootcamp Lecture 2Dynamics of gene regulation through ordinary differential equations ODEs James Sharpe EMBL Barcelona SpainSeminar Room Aula de Seminari 18 00 19 00Bootcamp Practical 2Practical exercises on laptops Numerically solve ODEs and plot the solutions analyse gene regulatory network dynamics Software python code Seminar Room Aula de Seminari 19 00 21 00DinnerOffsite Day 2 Sunday 15 June 2025 Time Barcelona Europe SpeakerLocation08 50 09 00Daily Testing and Welcome overview of the day09 00 09 45Bootcamp Lecture 3 Qualitative interpretation of the dynamics of GRN Phase portraits fixed points and stabilityAlejandro Torres S nchez EMBL Barcelona SpainSeminar Room Aula de Seminari 09 45 10 45Bootcamp Practical 3main trainer Alejandro Torres S nchez EMBL Barcelona SpainPractical exercises on laptops Create phase portraits and detect fixed points in gene regulatory models Classify their stability Trajectories in phase space connection with previous day Software python code Seminar Room Aula de Seminari 10 45 11 15Coffee break11 15 12 00Bootcamp Lecture 4Bifurcations how phase portraits can qualitatively change leading to different biological behavioursAlejandro Torres S nchez EMBL Barcelona SpainSeminar Room Aula de Seminari 12 00 13 00Bootcamp Practical 4main trainer Alejandro Torres S nchez EMBL Barcelona SpainPractical exercises on laptops saddle node pitchfork bifurcations biological examples Software python code Seminar Room Aula de Seminari 13 00 14 00LunchUPF Canteen14 00 14 45Bootcamp Lecture 5Modelling oscillations in gene expression Limit cycles Hopf bifurcations Jordi Garcia Ojalvo Universitat Pompeu Fabra SpainSeminar Room Aula de Seminari 14 45 15 45Bootcamp Practical 5main trainer Jordi Garcia Ojalvo Universitat Pompeu Fabra SpainPractical exercises on laptops Dynamics of gene regulation through ordinary differential equations ODEs Software python code Seminar Room Aula de Seminari 15 45 16 15Coffee break16 15 18 00Bootcamp debrief and discussionBreakout Area18 00Free evening Day 3 Monday 16 June 2025 Time Barcelona Europe SpeakerLocation08 50 09 00Daily Testing and Welcome overview of the day09 00 09 45Lecture 6 Spatial systems partial differential equations discretized continuum modelling of space diffusion different types of gradient formation interpretation of a gradient solving the French Flag Problem scale invariance positional information James Sharpe EMBL Barcelona SpainSeminar Room Aula de Seminari 09 45 10 45Practical 6main trainer James Sharpe EMBL Barcelona SpainPractical exercises on laptops Dynamics of gene regulation through ordinary differential equations ODEs Software LimbnetSeminar Room Aula de Seminari 10 45 11 15Coffee break11 15 12 00Lecture 7 Main classes of Turing pattern spots versus stripes boundary conditions creating a Pearson plot travelling waves versus stable patternsJames Sharpe EMBL Barcelona SpainSeminar Room Aula de Seminari 12 00 13 00Practical 7main trainer James Sharpe EMBL Barcelona SpainPractical exercises on laptops Dynamics of gene regulation through ordinary differential equations ODEs Software LimbnetSeminar Room Aula de Seminari 13 00 14 00LunchUPF Canteen14 00 14 45Lecture 8 Controlling self organised patterns with positional information how gradients could alter wavelength in 1D how 2D gradients could alter the spatial patterns example of limb development Limitations of modelling what it can and cannot doJames Sharpe EMBL Barcelona SpainSeminar Room Aula de Seminari 14 45 15 45Practical 8main trainer James Sharpe EMBL Barcelona SpainPractical exercises on laptops Qualitative interpretation of the dynamics of GRN Phase portraits fixed points and stabilitySeminar Room Aula de Seminari 15 45 16 15Coffee break16 15 19 00Group project session IBreakout Area19 00 20 00Keynote I Using phase portraits to understand molecular pattern formationBerta Verd University of Oxford United KingdomSeminar Room Aula de Seminari 20 00 22 00DinnerOffsite Day 4 Tuesday 17 June 2025 Time Barcelona Europe SpeakerLocation09 00 09 45Lecture 9More complex spatial systems Drosophila gap gene patterns temporal integration Sonic hedgehog in the neural tube multiple gradientsJordi Garcia Ojalvo Universitat Pompeu Fabra SpainSeminar Room Aula de Seminari 09 45 10 45Practical 9main trainer Jordi Garcia Ojalvo 4 assistantsPractical exercises on laptops on Bifurcations how phase portraits can qualitatively change leading to different biological behavioursSoftware python code Seminar Room Aula de Seminari 10 45 11 15Coffee break11 15 12 00Lecture 10Understanding the sources and impact of noise in biological systems gene regulatory networksJordi Garcia Ojalvo Universitat Pompeu Fabra SpainSeminar Room Aula de Seminari 12 00 13 00Practical 10main trainer Jordi Garcia Ojalvo 4 assistantsPractical exercises on laptops on Modelling oscillations in gene expression Limit cycles Hopf bifurcationsSoftware python code Seminar Room Aula de Seminari 13 00 14 00LunchUPF Canteen14 00 14 45Lecture 11Understanding the sources and impact of noise in biological systems spatial patterningJordi Garcia Ojalvo Universitat Pompeu Fabra SpainSeminar Room Aula de Seminari 14 45 15 45Practical 11main trainer Jordi Garcia Ojalvo 4 assistantsPractical exercises on laptops on Spatial systems partial differential equations discretized continuum modelling of space diffusion different types of gradient formation interpretation of a gradient solving the French Flag Problem scale invariance positional information Software python code Seminar Room Aula de Seminari 15 45 16 15Coffee break16 15 19 00Group project session IIBreakout Area19 00 20 00Keynote II Embryonic pattern formationJames Briscoe Francis Crick Institute United KingdomSeminar Room Aula de Seminari 20 00Free evening Day 5 Wednesday 18 June 2025 Time Barcelona Europe SpeakerLocation09 00 09 45Lecture 12Basics of agent based modelling ABM different types of agent interaction emergent behaviour in flocking The simplifying assumptions and possible pitfalls of the ABM approachAlexandria Volkening Purdue University USASeminar Room Aula de Seminari 09 45 10 45Practical 12main trainer Alexandria Volkening Purdue University USA 4 assistants Practical exercises on laptops on the topics of lecture 13 listed above Software NetLogo online Seminar Room Aula de Seminari 10 45 11 15Coffee break11 15 12 00Lecture 13Modelling pattern formation in an agent based model diffusion gene regulation networks and feedback on morphogenesisKatie Bentley Francis Crick Institute UKSeminar Room Aula de Seminari 12 00 13 00Practical 13main trainer Katie Bentley Francis Crick Institute UK 4 assistants Practical exercises on laptops on the topics of lecture 14 listed above Software NetLogo online Seminar Room Aula de Seminari 13 00 14 00LunchUPF Canteen14 00 14 45Lecture 14Modelling complex tissues stripe formation in zebrafishAlexandria Volkening Purdue University USASeminar Room Aula de Seminari 14 45 15 45Practical 14main trainer Alexandria Volkening Purdue University USA 4 assistants Practical exercises on laptops on the topics of lecture 15 listed above Software NetLogo online Seminar Room Aula de Seminari 15 45 16 15Coffee break16 15 18 15Flash talksBreakout Area18 15 19 00Networking and Meet the speakersBreakout Area19 00 20 00Keynote III Using Agent based Models to explain vasculogenesisKatie Bentley Francis Crick Institute UKSeminar Room Aula de Seminari 20 00 22 00DinnerOffsite Day 6 Thursday 19 June 2025 Time Barcelona Europe SpeakerLocation09 00 09 45Lecture 15Combining molecules with mechanics molecular patterning in vertex models using molecular patterns to control growth morphogenesis boundary sharpening combining signalling and cell behaviourJavier Buceta I SysBio CSIC UV SpainSeminar Room Aula de Seminari 09 45 10 45Practical 15main trainer Javier Buceta I SysBio CSIC UV Spain 4 assistants Practical exercises on laptops on the topics of lecture 7 listed above Software ChasteSeminar Room Aula de Seminari 10 45 11 15Coffee break11 15 12 00Lecture 16Morphogenesis anisotropic growth intercalation T1 2 3 transitions planar polarityJavier Buceta I SysBio CSIC UV SpainSeminar Room Aula de Seminari 12 00 13 00Practical 16main trainer Javier Buceta I SysBio CSIC UV Spain 4 assistants Practical exercises on laptops on the topics of lecture 8 listed above Software ChasteSeminar Room Aula de Seminari 13 00 14 00LunchUPF Canteen14 00 14 45Lecture 17Combining molecules with mechanics molecular patterning in vertex models using molecular patterns to control growth morphogenesis boundary sharpening combining signalling and cell behaviourJavier Buceta I SysBio CSIC UV SpainSeminar Room Aula de Seminari 14 45 15 45Practical 17main trainer Javier Buceta I SysBio CSIC UV Spain 4 assistants Practical exercises on laptops on the topics of lecture 9 listed above Software ChasteSeminar Room Aula de Seminari 15 45 16 15Coffee break16 15 19 00Group project session IIIBreakout Area19 00 20 00Keynote IV Vertex modelling to explain epithelial developmentAlex Fletcher University of Sheffield UKSeminar Room Aula de Seminari 20 00Free evening Day 7 Friday 20 June 2025 Time Barcelona Europe SpeakerLocation09 00 09 45Lecture 18The basics and maths of continuum mechanics force vectors and stress tensors etc linear elasticity and the stokes equations basic example of non uniform growthAlejandro Torres Sanchez EMBL Barcelona SpainSeminar Room Aula de Seminari 09 45 10 45Practical 18main trainer Alejandro Torres S nchez EMBL Barcelona SpainPractical exercises on laptops on the topics of lecture 10 listed above Software hiperlife Seminar Room Aula de Seminari 10 45 11 15Coffee break11 15 12 00Lecture 19Defining tissue geometries manual creation of geometries meshes segmentation of tissue geometry from image data triangulation tetrahedralization solving basic equationsAlejandro Torres Sanchez EMBL Barcelona SpainSeminar Room Aula de Seminari 12 00 13 00Practical 19main trainer Alejandro Torres S nchez EMBL Barcelona SpainPractical exercises on laptops on the topics of lecture 11 listed above Software hiperlifeSeminar Room Aula de Seminari 13 00 14 00LunchUPF Canteen14 00 14 45Lecture 20Combining molecules with mechanics molecular diffusion in FEM simple example of feedback between molecular gradient and morphogenesisAlejandro Torres Sanchez EMBL Barcelona SpainSeminar Room Aula de Seminari 14 45 15 45Practical 20main trainer Alejandro Torres S nchez EMBL Barcelona SpainPractical exercises on laptops on the topics of lecture 12 listed above Software hiperlifeSeminar Room Aula de Seminari 15 45 16 15Coffee break16 15 17 15Keynote V Using FEM to model how non uniform proliferation rates lead to controlled buckling and bending of wing disc epitheliumYanlan Mao University College London UKSeminar Room Aula de Seminari 17 15 18 45Group project presentationsSeminar Room Aula de Seminari 18 45 19 45Wrap up discussion and course debrief19 45 21 45DinnerOffsite Practical Information Registration fees and motivation letter The course is limited to 20 participants For selection purposes please note that your application will not be considered without a letter of motivation Registration Registration fees include admission course materials COVID 19 safety measures meals and coffee breaks This EMBO course includes accommodation and transportation to and from the hotel to the venue Academia 550PhD Student 550Industry 1100 NO visa support letters will be issued until payment of the registration fee is confirmed Confirmation and payment The registration fee should be paid only after acceptance to the course The results will be announced approximately 2 3 weeks after the application deadline Motivation letter submission After you have logged in and successfully registered you will receive an email asking you to submit your motivation letter Click on the link provided and enter your motivation letter in the text box provided Alternatively you can submit your motivation letter by clicking on the link on the confirmation page directly after registering Instructions Include your relevant skills experience and qualifications showing why you would be suitable for the course Explain why you would like to attend including what you can contribute and how you think you will benefit from the course Please note The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised For detailed instructions please watch our video on how to submit a course motivation letter Further details For further information about registration and motivation letter submission please refer to the FAQ page Financial assistance Financial assistance Limited financial assistance is provided by EMBO in the form of both registration fee waivers and travel grants Availability is limited to participants attending on site events and will be indicated during the abstract or motivation letter submission process Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course or conference Travel grant The travel grant will cover the cost of travel airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for any participant travelling to an EMBO Practical Course or EMBO Workshop up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Practical Course or EMBO Workshop Registration fees are only covered for EMBO Practical Courses or EMBO WorkshopsThe organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant EMBO Practical Courses and Workshops only For EMBO Practical Course or EMBO Workshop participants with children there is the possibility to apply for a childcare grant to offset child care costs incurred by participants or speakers when participating at a course or conference Eligible costs include fees for a babysitter or child care facility travel costs for a caregiver or travel costs for taking the child to the meeting etc Please note that priority will be given to early stage researchers A maximum amount of 500 EUR can be awarded per participant applying for an EMBO Childcare Grant In order to apply for this grant for EMBO Workshops you must be registered by the abstract submission deadline Boehringer Ingelheim Fonds travel grant Applies to selected courses only Availability will be indicated during the abstract or motivation letter submission process This grant covers costs related to your attendance at the course registration travel and accommodation costs The grant is restricted to PhD students and postdocs who conduct basic biomedical research Whether you are eligible to apply for a travel grant depends on when you received your university entrance qualification e g Abitur A Levels High School Diploma Final State Examination for PhD and MD students as well as graduates the university entrance qualification must not have been obtained more than 11 years ago at the time of the envisaged course for postdocs the university entrance qualification must not have been obtained more than 13 years ago at the time of the envisaged course Application You may apply for financial assistance when submitting your motivation letter for courses and abstract for conferences In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application For the Boehringer Ingelheim Fonds Travel Grant there is a pre application question during the motivation letter submission process and if selected you will be requested to complete a standard form and documentation consisting of your travel expense estimation Selection The scientific organisers will select the recipients of all financial assistance during the motivation letter or abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection is based on your current work or study location the reasons for needing financial support and the impact this event will have on your career Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details See our list of external funding opportunities For further information about financial assistance please refer to the FAQ page Accommodation and shuttles Hotel Accommodation has been pre booked for you at a nearby hotel for the default dates of 14 June to 21 June 2025 7 nights Please note that the course registration fee includes coverage of accommodation costs in twin rooms including breakfast Local transport The hotel is just a few minutes from the Collaboratorium space where the practical course will be held Further details The address of the hotel will be communicated later in the process Event software Event software The EMBL eCampus learning platform will be used to collaborate communicate and network with all of the course participants All participants will receive information on how to join shortly before the course We recommend using Chrome Safari or Mozilla Firefox browsers for eCampus Sponsors This course is supported by the Theory EMBL research programme which promotes theory guided paths to discovering understanding and conceptualising the underlying principles of complex and dynamic biological systems Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other events or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9...

Katie Bentley, James Sharpe, Alejandro Torres-Sanchez

EMBO Practical Course

EMBL Barcelona

11 June 2025

A FAIR and scalable workflow for plankton phenogenomics at single cell level

Edit

June 11, 2025 14:302025WebinarVirtual

Description High throughput single cell approaches have become increasingly applied in marine sciences Predominantly separated between single cell sequencing or single cell imaging the next frontier aims at connecting both generating complex data architecture to link environmental data with single cell images and sequences In this webinar we will share our ongoing initiative to generate a scalable and FAIR workflow to both visualise and sequence symbiosis in phytoplankton Please note this webinar does not include a recording or presentation slides for later access...

Virtual

10 June - 13 June 2025

The ageing genome: from mechanisms to disease

Edit

June 10, 2025 00:002025ConferenceEMBL Heidelberg, Virtual

Cancer genomics and transcriptomics

Edit

May 12, 2025 00:002025CourseVirtual

Description This course will focus on the analysis of data from genomic studies of cancer It will also highlight the application of transcriptomic analysis and single cell technologies in cancer Talks and interactive sessions will give an insight into the bioinformatic concepts required to analyse such data whilst practical sessions will enable the participants to apply statistical methods to the analysis of cancer genomics data under the guidance of the trainers Virtual courseParticipants will learn via a mix of pre recorded lectures live presentations and trainer Q A sessions Practical experience will be developed through group activities and trainer led computational exercises Live sessions will be delivered using Zoom with additional support and asynchronous communication via Slack Pre recorded material may be provided before the course starts that participants will need to watch read or work through to gain the most out of the actual training event In the week before the course there will be a brief induction session Computational practicals will run on EMBL EBI s virtual training infrastructure meaning participants will not require access to a powerful computer or install complex software on their own machines Participants will need to be available between the hours of 08 45 17 30 BST each day of the course Trainers will be available to assist answer questions and provide further explanations during these times...

Anca Belu

Virtual

Edit

April 29, 2025 00:002025ConferenceEMBL Heidelberg, Virtual

Description Overview Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Symposium overview The symposium will delve into the critical role of sustainable practices within the scientific community As researchers grapple with global challenges it becomes imperative to adopt environmentally responsible and socially equitable research methodologies This symposium will explore topics such as green laboratory practices the inspiring role of grassroots movements organisation s sustainability strategies and the vital role of funders always with an eye on the future By fostering a culture of sustainability within science we can reduce our ecological footprint enhance research integrity and ensure the long term viability of scientific research Through a series of keynote presentations panel discussions and interactive workshops participants will have the opportunity to engage with leading experts and share their own experiences in sustainable science By fostering interdisciplinary collaboration and knowledge sharing this event aims to inspire scientists to embrace sustainability as a core principle of their work This symposium is being hosted at EMBL Heidelberg and virtually as part of the SuReSymp programme of annual sustainable research symposiums It is being organised in collaboration with EMBO the Sustainable European Laboratories Network SELs and with support from the European Union s Climate Pact...

Brendan Rouse, Marta Rodríguez-Martínez, Philipp Weber, Martin Farley, Valeria Scagliotti

EMBL Heidelberg, Virtual

23 April 2025

From variant to drug target: using the expanded Open Targets Platform to explore the genetics of target discovery

Edit

April 23, 2025 15:002025WebinarVirtual

Description The Open Targets Platform is a comprehensive research tool that supports systematic identification and prioritisation of potential therapeutic drug targets By integrating publicly available datasets along with data generated by the Open Targets consortium the Platform builds and scores target disease associations Earlier this year the Platform was expanded through the inclusion of variant study and credible set information The Platform now includes comprehensive variant annotation and the results of state of the art large scale statistical analysis including fine mapping colocalisation and locus to gene assignment across all complex and molecular traits Drawing from the GWAS Catalog the eQTL Catalogue FinnGen the UK Biobank Pharma Proteomics Project and more users can browse over 2 6 million credible sets to build more robust therapeutic hypotheses This webinar will provide an introduction to the capabilities and use cases for the Open Targets Platform and demonstrate the impact of the newly introduced data These allow you to dig deeper into the GWAS evidence for a target disease association explore our analyses of GWAS and molecular QTL studies and relevant annotation data...

Virtual

16 April 2025

LLMs in bioinformatics Q&A session

Edit

April 16, 2025 13:002025WebinarVirtual

Description Join us for a live panel discussion as part of our ongoing webinar series Large Language Models and their applications in bioinformatics This interactive Q A session offers attendees the opportunity to engage with speakers from the series ask new questions and revisit key discussions You can submit your questions for the panel in advance using this document Questions for the panelThe panel will review and prioritise the questions submitted in this document along with those asked throughout the series before opening the floor to live queries from participants To find more details on the webinars from this series visit the event webpage https www ebi ac uk training events large language models and their applications bioinformatics...

Virtual

Edit

April 02, 2025 14:002025WebinarVirtual

Description This webinar will explore how Large Language Models LLMs can streamline the extraction of critical information from scientific texts focusing on patient derived cancer models PDCMs PDCMs are vital tools for cancer research and preclinical studies with a growing body of literature in this field However manually extracting and curating information from scientific texts is labor intensive and prone to delays In this session we will introduce two innovative approaches direct prompting and soft prompting Direct prompting uses manually created instructions to extract PDCM related entities while soft prompting leverages machine learning to train continuous vector prompts We will discuss our comparative evaluation using state of the art proprietary and open source LLMs demonstrating how tailored prompt engineering can elevate the performance of smaller open models to match proprietary counterparts This session will highlight the potential of LLMs to enhance domain specific knowledge extraction and accelerate research workflows...

Virtual

31 March - 4 April 2025

Microscopy data analysis: machine learning and the BioImage Archive

Edit

Edit

March 06, 2025 15:302025WebinarVirtual

Description UniProt is a comprehensive expert led publicly available database of protein sequence function and variation information It also encompasses a wealth of large scale proteomics data resources and tools that users from the proteomics community can benefit from This webinar will introduce proteomics data in UniProt and highlight resources that users with large protein datasets may find useful in analysing their data This will encompass our proteomes service how to carry out a peptide search and where to find large scale proteomics derived data in UniProt The webinar will then go on to briefly introduce programmatic access to the UniProt Proteins API and will give examples on how to download reference proteomes and download large scale proteomics datasets programmatically Finally the speakers will take live questions from the audience Attendees will have access to a Google Colab workbook following the webinar which will provide coding examples that they can use in their own analysis pipelines The UniProt APIs are available at https www uniprot org help programmatic access...

Virtual

5 March 2025

Developing a dataset for LLM projects

Edit

March 05, 2025 14:002025WebinarVirtual

Description As large language models LLMs continue to revolutionise artificial intelligence applications the importance of high quality data preparation has never been more critical This webinar dives into the art and science of preparing datasets for effective LLM training offering actionable insights for AI practitioners data scientists and engineers We will explore the end to end process of data preparation beginning with data collection strategies and progressing through cleaning preprocessing tokenisation and annotation Emphasis will be placed on identifying and mitigating biases managing multilingual datasets and ensuring data quality and diversity to enhance model performance Real world case studies will illustrate common pitfalls and solutions while hands on demonstrations will provide practical techniques for optimising datasets Participants will gain a deeper understanding of how well structured and curated data can significantly impact an LLM s capabilities reduce training costs and improve ethical AI outcomes Whether you are building LLMs from scratch or fine tuning existing models this session will equip you with the knowledge to leverage your data assets effectively Join us to unlock the potential of data preparation and enable your LLMs to achieve unparalleled performance and generalisation...

Virtual

3 March - 7 March 2025

Introduction to multi-omics data integration and visualisation

Edit

March 03, 2025 00:002025CourseEMBL-EBI

Meredith Willmott

EMBL-EBI

27 February 2025

Workshop on Artificial Intelligence Competencies: training challenges and needs of research infrastructures and core facilities

Edit

February 27, 2025 00:002025CourseEMBL-EBI

Description Update the application period is closed but additional spaces may be available please contact the organisers if interested The Biodata Developers BioDev Network Wellcome Sanger Institute and ELIXIR EMBL EBI as part of RItrainPlus project are organising a knowledge exchange workshop on Artificial Intelligence Competencies training challenges and needs of research infrastructures and core facilities The overall purpose of the workshop is to create a space to discuss the professional roles and competencies needed to support the implementation of Artificial Intelligence AI for research in research infrastructures RIs Core Facilities CFs and similar organisations as well as the training gaps and current actions they are already carrying out to address the training needs This will be an interactive workshop where attendees will actively participate through discussions group work or short presentations The workshop has been shaped with the input gathered through dedicated scoping discussions with different experts In particular we would like to thank the following experts and their organisations for their input Nina Norgren SciLifeLabFotis Psomopoulos Center for Research and Technology HellasDan MacLean The Sainsbury Lab TSL Edward Lukyamuzi Pan African Mosquito Control Association PAMCA Dr Michelle Skelton Data Science for Health Discovery and Innovation in Africa DS I Africa Helder Nakaya Albert Einstein Hospitals BrazilMoises Sotelo University of GuadalajaraRolanda Julius Data Science for Health Discovery and Innovation in Africa DS I Africa...

Juanita Riveros

EMBL-EBI

26 February 2025

Basics of Large Language Models - transformers to LLMs

Edit

February 26, 2025 14:002025WebinarVirtual

Description We will introduce Large Language Models LLMs focusing on their core architecture training methodologies practical applications and some important considerations We begin with a brief exploration of the transformer architecture examining how architectural choices and scaling laws have shaped modern language models We then investigate key training paradigms with particular emphasis on Reinforcement Learning from Human Feedback RLHF and instruction tuning while briefly touching on emerging approaches like Direct Preference Optimisation DPO The discussion progresses through the evolution of knowledge integration techniques from basic context stuffing to Retrieval Augmented Generation RAG highlighting their practical implications We will discuss the critical issue of hallucinations in LLM outputs providing concrete examples and verification strategies To conclude a quick overview of the current software landscape and immediate future developments in the field and a look ahead to the rest of the webinar series...

Virtual

24 February - 28 February 2025

January 29, 2025 15:302025WebinarVirtual

Description Ensembl creates and imports genome annotations including data on genes variations regulation and comparative genomics for vertebrates non vertebrates and key model organisms providing this information freely online This webinar will provide an introduction to the new Ensembl browser platform and demonstrate how to navigate the website to retrieve genomic data The new browser is also home to all data that would previously have been shared on the Ensembl Rapid Release site The webinar will highlight the improvements in the new platform and how these enhancements can significantly aid in genomic research Importantly participants will also be able to engage with the Ensembl outreach team to find sources of help and documentation...

Virtual

27 January - 31 January 2025

Computing skills for reproducible research: software carpentry

Edit

January 27, 2025 00:002025CourseEMBL Heidelberg, Virtual

Description OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview Course overview Computation is an integral part of today s research as data has grown too large or too complex to be analysed by hand An ever growing fraction of science is performed computationally but many scientists struggle with this aspect of research as they have not been properly trained in the necessary set of skills The result is that too much time is spent doing steps manually or using inefficient tools when progress could be faster This course provides training in several key tools with a focus on good development practices that encourage efficient and reproducible research computing Audience This course is aimed at researchers in the life sciences who wish to use or design analysis pipelines on individual or clusters of computers The target learner is familiar with some command line programmatic computer usage and wants to become more confident using these tools efficiently and reproducibly If you have written a for loop in some language before but do not know what Git or Nextflow is or at least are not very comfortable using them you may be the perfect fit for this workshop Modules Resources Introduction to the Unix shell Version control and history tracking with Git Introduction to scripting and basics of data analysis with Python Multi step analysis and pipeline management with Nextflow Best practices for reproducible analysis in high performance computing environments Learning outcomes After the workshop participants will be able to interact with a command line shell for local and remote computing needs write and organise their own scripts for data analysis use version control to keep track of and revert changes to their files implement efficient and reproducible pipelines that combine multiple tools and scripts execute and troubleshoot command line tools and pipelines on a high performance computing cluster Participant commitment There will be an onboarding session one week before the course starts to make sure everyone has installed the required software and that everyone to a good starting position for the 5 day hybrid course in January 2025 Full time attendance is required for the course duration Speakers Speakers trainers and staff Renato Alves EMBL Heidelberg Germany Anastasiia Grekova EMBL Heidelberg Germany Julian Hennies EMBL Heidelberg Germany Jean Karim H rich EMBL Heidelberg Germamy Sarah Kaspar EMBL Heidelberg Germany Dominik Kutra EMBL Heidelberg Germany Jacobo Miranda EMBL Heidelberg Germany Lisanna Paladin EMBL Heidelberg Germany Felix Schneider EMBL Heidelberg Germany Christian Schudoma EMBL Heidelberg Germany Francesco Tabaro EMBL Heidelberg Germany Christian Tischer EMBL Heidelberg Germany Thomas Weber EMBL Heidelberg Germany Mahnoor Zulfiqar EMBL Heidelberg Germany Scientific organisers Renato Alves EMBL Heidelberg Germany Lisanna Paladin EMBL Heidelberg Germany Christian Schudoma EMBL Heidelberg Germany Course organisers Iva Gavran Course and Conference Officer EMBL Heidelberg Germany Ellen Malovrh Scientific Training Officer EMBL Heidelberg Germany Programme Are you on social media Post using EMBLSoftwareCarpentry and don t forget to tag EMBLEvents Please note the below programme is still subject to changes Some pre course work such as installing software with estimated time 0 10 hours will be required and will be shared in advance of the course Some speakers may need to join virtually to give their lecture or Q A and the programme is subject to change Onboarding session Tuesday 21 January 2025 Time Europe Berlin SpeakerLocation15 00 17 00Onboarding session mandatory Virtual Day 1 Monday 27 January 2025 Time Europe Berlin SpeakerLocation08 40 08 50Bus from hotel to EMBL ATC EntranceISG Hotel08 50 09 00Coffee break and computer set upCourtyard Room A B09 00 09 30Arrival housenotes and course overviewCourtyard Room A B09 30 10 30Flashtalks from all participantsCourtyard Room A B10 30 10 50Coffee breakCourtyard Foyer10 50 12 20Intro to ShellCourtyard Room A B12 20 13 20LunchEMBL Canteen13 20 14 20Intro to ShellCourtyard Room A B14 20 14 40Coffee breakCourtyard Foyer14 40 16 10Intro to GitCourtyard Room A B16 10 16 30Coffee breakCourtyard Foyer16 30 17 30Intro to GitCourtyard Room A B17 30 18 00Daily feedbackCourtyard Room A B18 00 19 00Social activity19 00 20 00DinnerEMBL Canteen20 00 20 10Departure to HotelATC Entrance Day 2 Tuesday 28 January 2025 Time Europe Berlin SpeakerLocation08 40 08 50Bus from hotel to EMBL ATC EntranceISG Hotel08 50 09 00Coffee break and computer set upCourtyard Room A B09 00 10 30Intro to PythonCourtyard Room A B10 30 11 00Coffee breakCourtyard Foyer11 00 12 00Intro to PythonCourtyard Room A B12 00 13 00LunchEMBL Canteen13 00 14 00Intro to PythonCourtyard Room A B14 00 14 30Coffee breakCourtyard Foyer14 30 16 00Intro to PythonCourtyard Room A B16 00 16 30Coffee breakCourtyard Foyer16 30 18 00Intro to PythonCourtyard Room A B18 00 18 30Daily feedbackCourtyard Room A B18 30 19 30DinnerEMBL Canteen19 30 19 40Departure to HotelATC Entrance Day 3 Wednesday 29 January 2025 Time Europe Berlin SpeakerLocation08 40 08 50Bus from hotel to EMBL ATC EntranceISG Hotel08 50 09 00Coffee break and computer set upCourtyard Room A B09 00 10 30Intro to PythonCourtyard Room A B10 30 11 00Coffee breakCourtyard Foyer11 00 12 00Intro to PythonCourtyard Room A B12 00 13 00LunchEMBL Canteen13 00 14 00Intro to PythonCourtyard Room A B14 00 14 30Coffee breakCourtyard Foyer14 30 16 00Command line scripting with PythonCourtyard Room A B16 00 16 30Coffee breakCourtyard Foyer16 30 18 00Command line scripting with PythonCourtyard Room A B18 00 18 30Daily feedbackCourtyard Room A B18 30 19 30DinnerEMBL Canteen19 30 19 40Departure to HotelATC Entrance Day 4 Thursday 30 January 2025 Time Europe Berlin SpeakerLocation08 40 08 50Bus from hotel to EMBL ATC EntranceISG Hotel08 50 09 00Coffee break and computer set upCourtyard Room A B09 00 10 30Intro to SLURM with NextflowCourtyard Room A B10 30 11 00Coffee breakCourtyard Foyer11 00 12 00Intro to SLURM with NextflowCourtyard Room A B12 00 13 00LunchEMBL Canteen13 00 14 00Intro to SLURM with NextflowCourtyard Room A B14 00 14 30Group photo and coffee breakCourtyard Foyer14 30 16 00Intro to SLURM with NextflowCourtyard Room A B16 00 16 30Daily feedbackCourtyard Room A B16 30 17 00World of Molecular Biology tour for onsite participants onlyImaging centre17 00 17 45Bus to city centre with a stop at ISG hotel 17 45 19 00Free time19 00 21 30Downtown dinner Day 5 Friday 31 January 2025 Time Europe Berlin SpeakerLocation08 40 08 50Bus from hotel to EMBL ATC EntranceISG Hotel08 50 09 00Coffee break and computer set upCourtyard Room A B09 00 10 30Best practices in HPC environmentCourtyard Room A B10 30 11 00Coffee breakCourtyard Foyer11 00 12 00Best practices in HPC environmentCourtyard Room A B12 00 13 00LunchEMBL Canteen13 00 14 00Best practices in HPC environmentCourtyard Room A B14 00 15 00Debrief and wrap upCourtyard Foyer15 00 15 30Bus to train station and downtownATC Entrance Practical information Registration fees and motivation letter The course is limited to 15 virtual and 15 onsite participants For selection purposes please note that your application will not be considered without a letter of motivation Registration Onsite registration fees include admission course materials meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Virtual registration fees include access to live streamed course content lectures practical sessions discussion rounds as well as any learning activities in the virtual learning platform OnsiteVirtualAcademia 425 190PhD Student 425 190Industry 750 250 A letter to support your visa application will be issued on request once payment of the registration fee is confirmed We recommend that you book your visa appointment as soon as possible to avoid any delay with your visa application Confirmation and payment The registration fee should be paid only after acceptance to the course The results will be announced approximately 2 3 weeks after the application deadline Motivation letter submission After you have logged in and successfully registered you will receive an email asking you to submit your motivation letter Click on the link provided and enter your motivation letter in the text box provided Alternatively you can submit your motivation letter by clicking on the link on the confirmation page directly after registering Instructions Include your relevant skills experience and qualifications showing why you would be suitable for the course Explain why you would like to attend including what you can contribute and how you think you will benefit from the course Please note The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised For detailed instructions please watch our video on how to submit a course motivation letter Further details For further information about registration and motivation letter submission please refer to the FAQ page Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of registration fee waivers and childcare grants Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waivers The fee waiver will cover the registration sum that you have paid to attend the course Childcare grants There is the possibility to apply for a childcare grant to offset child care costs incurred by participants speakers trainers and organisers when attending a course Eligible costs include but are not limited to fees for a babysitter or child care facility and travel costs for a caregiver Please note that priority will be given to early stage researchers There is a limited amount of funding available for the childcare grants and funds will be distributed amongst eligible applicants Boehringer Ingelheim Fonds travel grant Applies to selected courses only Availability will be indicated during the abstract or motivation letter submission process This grant covers costs related to your attendance to the course registration travel and accommodation costs The grant is restricted to PhD students and postdocs who conduct basic biomedical research Whether you are eligible to apply for a travel grant depends on when you received your university entrance qualification e g Abitur A Levels High School Diploma Final State Examination for PhD and MD students as well as graduates the university entrance qualification must not have been obtained more than 11 years ago at the time of the envisaged course for postdocs the university entrance qualification must not have been obtained more than 13 years ago at the time of the envisaged course Application If you are attending virtually you can apply for financial assistance in the submission portal by the abstract deadline Read the instructions on how to apply for financial assistance Only submissions for financial assistance will be accepted Presentation abstracts cannot be submitted here and will be declined In your application you will be asked to summarise your current work answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application For some events applications for Childcare Grants will still be done by email Information about the grant will be sent out shortly after the abstract motivation letter deadline Please contact the event Conference Officer if you have any questions Selection The scientific organisers will select the recipients of registration fee waivers during the participant selection process for courses Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection for registration fee waivers and travel grants is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Childcare grants will be allocated in the same timeframe 6 8 weeks before the event start date Please note that priority will be given to early stage researchers Further details Check out this list of external funding opportunities For further information about financial assistance please refer to the FAQ page Accommodation and travel Hotel Accommodation is not included in the registration fee Participants are expected to book and pay for their own accommodation A mix of single and twin rooms have been reserved for 5 nights from 26 to 31 January 2025 at the ISG hotel Single rooms are limited and will be available on a first come first served basis After the selection process selected participants should contact the hotel directly to make a booking with a booking code code of your course e g SWC25 01 by the deadline of 26 December 2024 We recommend that all course participants stay at the dedicated hotel for the course Travel information For travel information please see here If you are travelling to the conference within Germany then you are eligible for the Deutsche Bahn Event Ticket called the Veranstaltungsticket in German This will result in a lower ticket price if your travel distance to Heidelberg is more than 100 km You need to provide proof of your event attendance when purchasing the ticket For more information in English see here or in German see here You can book your ticket here Local transport Shuttle buses will go from the ISG Hotel to EMBL and back mornings and evenings A bus schedule and location of the bus stops will be made available prior to the meeting Further details Address EMBL Heidelberg Meyerhofstra e 1 69117 Heidelberg Germany For more information about accommodation and travel please refer to the FAQ page On site information Catering All meals and coffee breaks are included in the registration fee Our catering staff will prepare a wide variety of vegetarian meals meat and fish dishes soups pasta fresh fruit and vegetables as well as a variety of desserts Please wear your badge at all times when serving yourself No food or drinks are allowed in the laboratories Electricity and charging station In most places the electricity is 220 volts AC 50 cycles An adaptor and a plug that fits the German socket may be needed for your appliances laptop i e American Japanese etc A USB charging station for electronic devices is available at the registration desk EMBL Merchandise If you are interested in purchasing EMBL merchandise products presented in the glass display in the registration area please email the EMBL shop to place an order or get in contact with your Course Organiser Kindly note the EMBL shop is only open upon request and all purchases must be made in cash Euros only Health and safety notes Please read EMBL s COVID 19 safety policy for on site events Do not smoke in any EMBL building Eating and drinking is prohibited in all laboratories Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required The first aid room is located next to the ATC Registration Desk room 10 205 Dial the Emergency number 222 from any EMBL internal phone only Where is the accident What happened How many injured Emergency number 06221 387 7821 from mobile phones Please report all accidents to the conference officer at the registration desk In case of fire Press the nearest fire alarm button or the Emergency number 222 from any internal phone A loud fire alarm will go off if an evacuation is required On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting points Do not use the lifts Beyond first aid Please remember to bring your own medication if needed to the conference Note that the next pharmacy is a 4 minute drive from the EMBL but for many medications you will be required to see a doctor to get a prescription Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg In any case the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary Internet Wi Fi is available on campus Log in using the EMBL Events network and the event specific password which will be provided on site The eduroam network secure worldwide roaming access service developed for the international research and education community is also available Lost and found Lost and Found items are kept at the registration desk until the end of the conference Luggage There are lockers available on site to store your luggage which require a 2 EURO coin to operate There is another luggage room on level E0 which is free to use but remains unlocked during the conference Nursing room There is a nursing room available in the ATC Rooftop Lounge on level A29 Photography During the conference an EMBL Photographer may be taking photos If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Printing We can help to print your boarding pass train ticket Please send it to events embl de and collect your print outs at the registration desk Room for prayer yoga and meditation There is a room for prayer meditation and yoga located on level E0 behind the Auditorium Please be respectful of others using the room Sightseeing A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing Travel to and from the venue During the event we provide conference shuttle buses to and from EMBL In addition there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time Information on the shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page Map to walk from ISG Hotel to EMBL Technical requirements and event software Technical requirements Below you will find the software and technical requirements for this course You will need admin rights to be able to install the software on your computer and we recommend you try this before the course If you do not have admin rights please contact your technical support team in advance to make sure the software can be installed Below you will find the software and technical requirements for this course On site participants need to bring their own laptops which will be used to remotely access EMBL virtual machines with pre installed software All participants will be requested to install software before the course Please make sure to bring the laptop with the installed software to the course You will need admin rights to install the software required to access the virtual machines If you do not have admin rights please contact your technical support team in advance to make sure the software can be installed If you have a non standard HDMI port other than type A you need to bring an adaptor Keyboard and PC mouse are available for use with a standard USB port If you have a different port type such as USB C you will need to bring your own Additional software The EMBL eCampus learning platform will be used to collaborate communicate and network with all of the course participants All participants will receive information on how to join shortly before the course We recommend using Chrome Safari or Mozilla Firefox browsers for eCampus Zoom will be used for the live talks and Q A sessions More information will be provided closer to the start of the course Other information While using the software during the course please make sure you have nothing else using your bandwidth We recommend using a wired connection Virtual participation guidelines Guidelines Do not broadcast the course to unregistered participants Do not share your login details with others You are encouraged to tweet and post about the event Tweet unless the speaker specifically says otherwise but be mindful of unpublished data Please do not capture transmit or redistribute data presented at the meeting Additional information can be found in our Code of Conduct Health and well being It is important to stay healthy and move around especially when you are attending an event virtually We have put together a few coffee break stretches and yoga videos in eCampus for you to enjoy during the event How to ask questions Questions during and after the talks can be asked in the live streaming platform If time runs out or you think of a question later you can use the EMBL eCampus forum or send a direct message to the speaker trainer Time zone The programme is planned based on the Europe Berlin time zone unless otherwise stated As many virtual participants are attending from around the world we do our best to accommodate as many time zones as possible when creating the programme Please take your time zone into consideration when planning your attendance Additional information Please find additional information including FAQs and terms and conditions on our Information for Participants page Sponsors Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other events or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9...

Renato Alves, Lisanna Paladin, Christian Schudoma

EMBL Course

EMBL Heidelberg, Virtual

15 January 2025

An introduction to EMBL-EBI resources

Edit

January 15, 2025 15:302025WebinarVirtual

Description EMBL EBI is the home of the world s most comprehensive range of freely available molecular databases and resources Our resources help researchers share and analyse data and perform complex queries in many different ways Join us for a tour of the core data resources at EMBL EBI During this webinar we will introduce the types of data available how you can search for data and the various ways of getting assistance We will also discuss the role of EMBL EBI in making data open and accessible and how you can include EMBL EBI data in your workflows We will also provide information on further online training to help you learn more about specific topics in bioinformatics and EMBL EBI resources including an introduction to the training collections The collections bring together videos and online tutorials on a specific topic to help get started...

Virtual

14 January - 16 January 2025

Primer for predocs 2025

Edit

January 14, 2025 00:002025CourseEMBL-EBI

Description This course is aimed to provide an orientation for new predocs to EMBL EBI Databases and services will be introduced along with other useful information for starting out at EMBL EBI...

Juanita Riveros

EMBL-EBI

11 December 2024

Uncovering protein function with UniProt

Edit

December 11, 2024 15:302024WebinarVirtual

Description UniProt provides the scientific community with a freely accessible collection of protein sequence and functional information and is one of the most widely used protein resources in the world This webinar will cover what functional information is available in UniProt and where that information comes from It will also describe how the information is added to the resource and how to find it on the UniProt website...

Virtual

4 December 2024

Calculating polygenic scores with the Polygenic Score Catalog Calculator

Edit

December 04, 2024 15:302024WebinarVirtual

Description Polygenic scores PGS are a measurement which represents genetic predisposition for a heritable trait or phenotype by aggregating the effects of hundreds to millions of genetic variants into a single number The PGS Catalog is the world s largest FAIR finable accessible interoperable and reusable repository of PGS along with the relevant metadata required to evaluate and reuse them PGS have emerged as a commonly used genomic tool that have multiple research applications and potential clinical applications This webinar will demonstrate how to use scoring files from the PGS Catalog or custom files to calculate PGS in your own samples using the PGS Catalog Calculator pgsc calc The pgsc calc software reproducibly automates PGS calculation in commonly used genotyping formats plink VCF alongside capabilities for adjusting PGS in the context of genetic ancestry necessary for proper interpretation of PGS across diverse populations This webinar introduces the software and describes the ancestry adjustment process included in the Calculator along with information about how to run the tool and interpret results...

Virtual

3 December - 6 December 2024

Hands-on course for sample preparation and data analysis in proteomics

Edit

December 03, 2024 00:002024CourseEMBL Heidelberg

Description OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview Course overview The course will give an introduction to the theoretical aspects of the analysis of proteins peptides by mass spectrometry Participants will get hands on experience in sample preparation for a quantitative comparison across samples and perform a state of the art sample preparation and tandem mass tag labelling Samples prepared by the participants will be measured by liquid chromatography tandem mass spectrometry In a session focused on bioinformatics analysis participants will use FragPipe and FragPipe Analyst in order to process the acquired data Audience The course is intended for scientists that use or want to use proteomics for their research Applicants should have an understanding of protein biology and should know the principle of proteomics Ideally they have some prior experience with proteomics either directly or through collaborators or facilities Modules Sample preparation and data acquisition Introduction to MS technology Useful online tools for proteomics Applications in proteomics TMT history theory and applications Experimental design principles From spectra to spreadsheet tables with FragPipe Data assessment quality control from spreadsheet outputs Differential abundance analysis with FragPipe Analyst Learning outcomes State of the art sample preparation Learning which aspects of sample preparation can influence the outcome of the experiment Getting insights into different proteomics applications Optimal experimental design Basic understanding of data analysis Visualisation of proteomics data Speakers Speakers trainers and staff Isabelle Becher EMBL Heidelberg Germany Mira Burtscher EMBL Heidelberg Germany Per Haberkant EMBL Heidelberg Germany Dominic Helm German Cancer Research Center DKFZ Germany Sarah Kaspar EMBL Heidelberg Germany Michal Nadler Holly Thermo Fisher Scientific Germany Mandy Rettel EMBL Heidelberg Germany Mikhail Savitski EMBL Heidelberg Germany Suparat Scheu EMBL Heidelberg Germany Jennifer Schwarz EMBL Heidelberg Germany Frank Stein EMBL Heidelberg Germany Scientific Organisers Mandy Rettel EMBL Heidelberg Germany Mikhail Savitski EMBL Heidelberg Germany Frank Stein EMBL Heidelberg Germany Event organisers Swetlana Krez Scientific Training Officer EMBL Heidelberg Germany Julia Patricia Nohle Course and Conference Officer EMBL Heidelberg Germany Programme Are you on social media Post using EMBLProteomics and don t forget to tag EMBLEvents Some speakers may need to join virtually to give their lecture or Q A and the programme is subject to change Day 1 Tuesday 3 December 2024 Time Europe Berlin ProgrammeLocation09 00 09 15Registration and welcomeFlex Lab A B09 15 09 45Introduction to EMBL and housenotes incl Lab safetyFlex Lab A B09 45 10 15Course overview and introduction to Proteomics Core FacilityFlex Lab A B10 15 10 45Icebreaking activity Flash talks by participants Flex Lab A B10 45 11 00Coffee BreakFlex Lab A B11 00 12 00Lecture Sample preparationMandy Rettel EMBL Heidelberg GermanyFlex Lab A B12 00 13 00LunchEMBL Canteen13 15 14 30Practical 1 Cell lysis Solubility assayPer Haberkant EMBL Heidelberg GermanyMandy Rettel EMBL Heidelberg GermanyJennifer Schwarz EMBL Heidelberg GermanyFrank Stein EMBL Heidelberg GermanyIsabelle Becher EMBL Heidelberg GermanyTraining Lab B14 30 15 15Practical 2 Protein determination by Tryptophan assayPer Haberkant EMBL Heidelberg GermanyMandy Rettel EMBL Heidelberg GermanyJennifer Schwarz EMBL Heidelberg GermanyFrank Stein EMBL Heidelberg GermanyIsabelle Becher EMBL Heidelberg GermanyTraining Lab B15 15 15 45Coffee breakFlex Lab A B15 45 17 15Practical 3 Reduction alkylation SP3 protocol digestion including photosession with internal Photographer no participation required Per Haberkant EMBL Heidelberg GermanyMandy Rettel EMBL Heidelberg GermanyJennifer Schwarz EMBL Heidelberg GermanyFrank Stein EMBL Heidelberg GermanyIsabelle Becher EMBL Heidelberg GermanyTraining Lab B17 15 18 15MS gameFlex Lab A B Training Lab B18 15 19 45DinnerEMBL Canteen Day 2 Wednesday 4 December 2024 Time Europe Berlin ProgrammeLocation09 00 09 15Overview of the dayFlex Lab A B Training Lab B09 15 10 10Practical 4 Peptide extraction TMT labellingPer Haberkant EMBL Heidelberg GermanyMandy Rettel EMBL Heidelberg GermanyJennifer Schwarz EMBL Heidelberg GermanyFrank Stein EMBL Heidelberg GermanyIsabelle Becher EMBL Heidelberg GermanyTraining Lab B10 10 10 20Coffee breakFlex Lab A B10 20 10 50Lecture TMT theory and technical aspects Michal Nadler Holly Thermo Fisher Scientific GermanyFlex Lab A B10 50 11 30Lecture TMT applicationMikhail Savitski EMBL Heidelberg GermanyFlex Lab A B11 30 12 30Practical 5 Quenching Multiplexing Sample desaltingPer Haberkant EMBL Heidelberg GermanyMandy Rettel EMBL Heidelberg GermanyJennifer Schwarz EMBL Heidelberg GermanyFrank Stein EMBL Heidelberg GermanyIsabelle Becher EMBL Heidelberg GermanyTraining Lab B12 30 13 30Lunch breakEMBL Canteen13 30 15 00Lecture Introduction to MS technologyDominic Helm German Cancer Research Center DKFZ GermanyFlex Lab A B15 00 15 30Q A session with coffeeFlex Lab A B15 30 16 00Practical 6 Load samples on Mass specPer Haberkant EMBL Heidelberg GermanyMandy Rettel EMBL Heidelberg GermanyJennifer Schwarz EMBL Heidelberg GermanyFrank Stein EMBL Heidelberg GermanyIsabelle Becher EMBL Heidelberg GermanyProteomics Core Facility16 00 16 30Lecture Workflow overviewFrank Stein EMBL Heidelberg GermanyFlex Lab A B16 30Free evening Day 3 Thursday 5 December 2024 Time Europe Berlin ProgrammeLocation09 00 09 15Overview of the dayComputer Training Lab09 15 09 40Lecture Raw file analysis with FreestyleMichal Nadler Holly Themo fisher scientific GermanyComputer Training Lab09 40 10 30Lecture Raw file processing with FragPipeFrank Stein EMBL Heidelberg GermanyComputer Training Lab10 30 10 50Coffee breakComputer Training Lab10 50 12 00Computer Practical Analysis of own data with FragpipePer Haberkant EMBL Heidelberg Germany Mandy Rettel EMBL Heidelberg Germany Jennifer Schwarz EMBL Heidelberg Germany Frank Stein EMBL Heidelberg GermanyMira Burtscher EMBL Heidelberg GermanyComputer Training Lab12 00 13 00Lunch breakcourse photo around 12 50 EMBL Canteen13 00 14 00Lecture What data can tell you about your experimental workflow Frank Stein EMBL Heidelberg GermanyComputer Training Lab14 00 14 25Coffee breakComputer Training Lab14 25 16 15Lecture Practical Experimental designSarah Kaspar EMBL Heidelberg GermanyComputer Training Lab16 15 16 40Coffee breakComputer Training Lab16 40 17 40Computer Practical Usage of bioinformatics toolsPer Haberkant EMBL Heidelberg GermanyMandy Rettel EMBL Heidelberg GermanyJennifer Schwarz EMBL Heidelberg GermanyFrank Stein EMBL Heidelberg GermanyMira Burtscher EMBL Heidelberg GermanyComputer Training Lab17 45 18 00Bus from EMBL downtown18 00 19 00Heidelberg Christmas market19 00 21 30Dinner downtown Day 4 Friday 6 December 2024 Time Europe Berlin ProgrammeLocation09 00 09 15Overview of the dayFlex Lab A B09 15 10 30Lecture Quantitative and statistical data analysis workflowFrank Stein EMBL Heidelberg GermanyComputer Training Lab10 30 10 50Coffee breakComputer Training Lab10 50 11 30Computer Practical Fragpipe AnalystPer Haberkant EMBL Heidelberg GermanyMandy Rettel EMBL Heidelberg GermanyJennifer Schwarz EMBL Heidelberg GermanyFrank Stein EMBL Heidelberg GermanyMira Burtscher EMBL Heidelberg GermanyComputer Training Lab11 30 12 30Lecture Applications in proteomicsPer Haberkant EMBL Heidelberg GermanyFlex Lab A B12 30 13 30LunchEMBL Canteen13 30 14 15Lecture PhosphoproteomicsJennifer Schwarz EMBL Heidelberg GermanyFlex Lab A B14 15 15 30Q A session Discussion of individual projects with PCFFlex Lab A B15 30 16 00Tour of Imaging Centre Exhibition World of Molceular Biology Imaging Centre16 15Bus to Heidelberg train station and city center Practical information Registration fees and motivation letter The course is limited to 16 participants For selection purposes please note that your application will not be considered without a letter of motivation Registration Registration fees include admission course materials meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Academia 575PhD Student 575Industry 1100 A letter to support your visa application will be issued on request once payment of the registration fee is confirmed We recommend that you book your visa appointment as soon as possible to avoid any delay with your visa application Confirmation and payment The registration fee should be paid only after acceptance to the course The results will be announced approximately 2 3 weeks after the application deadline Motivation letter submission After you have logged in and successfully registered you will receive an email asking you to submit your motivation letter Click on the link provided and enter your motivation letter in the text box provided Alternatively you can submit your motivation letter by clicking on the link on the confirmation page directly after registering Instructions Include your relevant skills experience and qualifications showing why you would be suitable for the course Explain why you would like to attend including what you can contribute and how you think you will benefit from the course Please note The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised For detailed instructions please watch our video on how to submit a course motivation letter Further details For further information about registration and motivation letter submission please refer to the FAQ page Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of registration fee waivers travel grants and childcare grants Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course Travel grant The travel grant will cover the cost of travel airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Course within Europe up to 1000 for participants travelling to an EMBL Course from outside Europe up to 500 for any participant travelling to an EMBO Practical Course up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Practical Course up to 700 for any participant working in Croatia Czech Republic Estonia Greece Hungary Italy Lithuania Luxembourg Poland Slovenia and Turkey travelling to an EMBO Practical Course Registration fees are only covered for EMBO Practical Courses The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant There is the possibility to apply for a childcare grant to offset child care costs incurred by participants speakers trainers and organisers when attending a course Eligible costs include but are not limited to fees for a babysitter or child care facility and travel costs for a caregiver Please note that priority will be given to early stage researchers There is a limited amount of funding available for the childcare grants and funds will be distributed amongst eligible applicants Boehringer Ingelheim Fonds travel grant Applies to selected courses only Availability will be indicated during the motivation letter submission process This grant covers costs related to your attendance at the course registration travel and accommodation costs The grant is restricted to PhD students and postdocs who conduct basic biomedical research Whether you are eligible to apply for a travel grant depends on when you received your university entrance qualification e g Abitur A Levels High School Diploma Final State Examination for PhD and MD students as well as graduates the university entrance qualification must not have been obtained more than 11 years ago at the time of the envisaged course for postdocs the university entrance qualification must not have been obtained more than 13 years ago at the time of the envisaged course Application You may apply for financial assistance when submitting your motivation letter for courses In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application For the Boehringer Ingelheim Fonds Travel Grant there is a pre application question during the motivation letter submission process and if selected you will be requested to complete a standard form and documentation consisting of your travel expense estimation Selection The scientific organisers will select the recipients of registration fee waivers and travel grants during the motivation letter or abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection for registration fee waivers and travel grants is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Childcare grants will be allocated in the same timeframe 6 8 weeks before the event start date Please note that priority will be given to early stage researchers Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details See our list of external funding opportunities and for further information about financial assistance please refer to the FAQ page Accommodation and travel Hotel Accommodation is not included in the registration fee Participants are expected to book and pay for their own accommodation A mix of single and twin rooms have been reserved for 4 nights 2 6 December 2024 at ISG Hotel Single rooms are limited and will be available on a first come first served basis After the selection process selected participants should contact the hotel directly to make a booking with booking code SDP24 01 by the deadline of Tuesday 5 November 2024 We recommend that all course participants stay in the dedicated hotel for the course Travel information For travel information please see here If you are travelling to the conference within Germany then you are eligible for the Deutsche Bahn Event Ticket called the Veranstaltungsticket in German This will result in a lower ticket price if your travel distance to Heidelberg is more than 100 km You need to provide proof of your event attendance when purchasing the ticket For more information in English see here or in German see here You can book your ticket here Local transport Shuttle buses will go from the ISG Hotel to EMBL and back mornings and evenings A bus schedule and location of the bus stops will be made available prior to the meeting Further details Address EMBL Heidelberg Meyerhofstra e 1 69117 Heidelberg GermanyFor more information about accommodation and travel please refer to the FAQ page On site information Catering All meals and coffee breaks are included in the registration fee Our catering staff will prepare a wide variety of vegetarian meals meat and fish dishes soups pasta fresh fruit and vegetables as well as a variety of desserts Please wear your badge at all times when serving yourself No food or drinks are allowed in the laboratories Electricity and charging station In most places the electricity is 220 volts AC 50 cycles An adaptor and a plug that fits the German socket may be needed for your appliances laptop i e American Japanese etc A USB charging station for electronic devices is available at the registration desk EMBL Merchandise If you are interested in purchasing EMBL merchandise products presented in the glass display in the registration area please email the EMBL shop to place an order or get in contact with your Course Organiser Kindly note the EMBL shop is only open upon request and all purchases must be made in cash Euros only Health and safety notes Please read EMBL s COVID 19 safety policy for on site events Do not smoke in any EMBL building Eating and drinking is prohibited in all laboratories Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required The first aid room is located next to the ATC Registration Desk room 10 205 Dial the Emergency number 222 from any EMBL internal phone only Where is the accident What happened How many injured Emergency number 06221 387 7821 from mobile phones Please report all accidents to the conference officer at the registration desk In case of fire Press the nearest fire alarm button or the Emergency number 222 from any internal phone A loud fire alarm will go off if an evacuation is required On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting points Do not use the lifts Beyond first aid Please remember to bring your own medication if needed to the conference Note that the next pharmacy is a 4 minute drive from the EMBL but for many medications you will be required to see a doctor to get a prescription Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg In any case the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary Internet Wi Fi is available on campus Log in using the EMBL Events network and the event specific password which will be provided on site The eduroam network secure worldwide roaming access service developed for the international research and education community is also available Lost and found Lost and Found items are kept at the registration desk until the end of the conference Luggage There are lockers available on site to store your luggage which require a 2 EURO coin to operate There is another luggage room on level E0 which is free to use but remains unlocked during the conference Nursing room There is a nursing room available in the ATC Rooftop Lounge on level A29 Photography During the conference an EMBL Photographer may be taking photos If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Printing We can help to print your boarding pass train ticket Please send it to events embl de and collect your print outs at the registration desk Room for prayer yoga and meditation There is a room for prayer meditation and yoga located on level E0 behind the Auditorium Please be respectful of others using the room Sightseeing A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing Travel to and from the venue During the event we provide conference shuttle buses to and from EMBL In addition there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time Information on the shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page Map to walk from ISG Hotel to EMBL Additional information Address EMBL Heidelberg Meyerhofstra e 1 69117 Heidelberg Germany ATC orientation map Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page Event software Event software The EMBL eCampus learning platform will be used to collaborate communicate and network with all of the course participants All participants will receive information on how to join shortly before the course We recommend using Chrome Safari or Mozilla Firefox browsers for eCampus Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page COVID 19 related questions COVID 19 information for on site events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Event partner Event sponsors Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other events or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9...

Mandy Rettel, Mikhail Savitski, Frank Stein

EMBL Course

EMBL Heidelberg

28 November 2024

Small molecule chemistry: from proteins to pathways

Edit

November 28, 2024 00:002024CourseVirtual

Description Small molecules play an important role in biological systems They provide the precursors to macromolecules have roles in cell signalling and regulation and can be used to treat diseases To understand the role of small molecules we can study their binding interactions with macromolecular targets such as nucleic acids and proteins and the functional impact on the target and biological pathways This six hour virtual workshop will provide participants with an opportunity to gain hands on experience of using EMBL EBI tools and resources to assess the impact of drugs on their protein target and place these interactions within the context of biological pathways During this course we ll explore the biological effects of small molecules using a therapeutic drug as an example We ll consider a workflow that investigates drug binding to a protein target and the downstream pathway effects EMBL EBI tools and resources will be used to identify small molecule drugs evaluate protein binding and investigate pathway effects...

Juanita Riveros

Virtual

27 November 2024

Navigating patent data with SureChEMBL

Edit

November 27, 2024 15:302024WebinarVirtual

Description Patents are legal documents that grant inventors exclusive rights for a limited time in return for publicly disclosing their innovations In the pharmaceutical industry thousands of patents are published annually making information about new drug candidates and potential applications available to the public Hosted at EMBL EBI SureChEMBL provides access to over 160 million patents annotated to highlight chemical and biomedical entities With a suite of tools designed for exploring patent literature SureChEMBL serves as a valuable resource for scientific data in drug discovery This webinar will introduce the SureChEMBL web interface and demonstrate efficient ways to navigate patent data...

Virtual

20 November 2024

Investigating gene function and human disease through data on the IMPC portal

Edit

November 20, 2024 15:302024WebinarVirtual

Description The International Mouse Phenotyping Consortium IMPC is a resource created by an international collaborative effort from 21 research institutions aiming to identify the function of every mammalian protein coding gene using the mouse as a model organism Currently the IMPC has generated knockout lines for 8 901 mouse genes and studied them systematically to determine their function in different biological systems and their role in disease This webinar will offer an overview of how IMPC data is generated along with a guided tour of the website showcasing key features and available data We will also explore how phenotype data can be used to investigate Mendelian diseases and how the PhenoDigm algorithm can be applied to identify new models of human disease gene associations...

Virtual

19 November - 22 November 2024

Quantitative biology to molecular mechanisms

Edit

November 19, 2024 00:002024ConferenceEMBL Heidelberg, Virtual

Description OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview Late onsite registration is still available Please reach out to events embl org to request it This conference will take place at EMBL Heidelberg with the option to attend virtually and is being organised by EMBL with generous support from the Bayer Foundation Conference overview Recent decades have witnessed a profound transformation in molecular biology research fueled by revolutionary technologies that have greatly enhanced our ability to systematically and quantitatively measure biological molecules The use of genomics proteomics and imaging have become routine generating vast amounts of high resolution data that characterise biological systems across multiple scales ranging from molecules to organisms This technological leap allows us to describe biological systems in quantitative terms with unprecedented resolution and provides a solid foundation for formulating mechanistic models that elucidate the intricacies of biological functions Quantitative biology to molecular mechanisms formerly From functional genomics to systems biology aims to bridge the gap between technologies and scales serving as a platform for the emergence of ideas and concepts to model complex biological systems Leaders in genomics functional proteomics quantitative imaging microscopy and theory will gather to discuss their data and models transcending their respective fields of expertise The meeting will be bridging three interconnected themes where systems level approaches in molecular biology research are transforming our understanding of biological systems A large fraction of the talks 20 will be selected from abstracts with a priority for early stage researchers Session topics Systems to function Systems to molecular mechanisms Systems to disease Speakers Speakers Lacramioara Bintu Stanford University USA Anne Claude Gingras Lunenfeld Tanenbaum Research Institute Canada Luca Giorgetti Friedrich Miescher Institute for Biomedical Research Switzerland James Hackett EMBL Rome Italy Anders Sejr Hansen MIT Biological Engineering USA Denes Hnisz Max Planck Institute for Molecular Genetics Germany Joanna Jachowicz Institute of Molecular Biotechnology Austria Hartland Jackson Lunenfeld Tanenbaum Research Institute Canada Mo Khalil Boston University USA Tineke Lenstra Netherlands Cancer Institute The Netherlands Kathryn Lilley University of Cambridge UK Fan Liu Leibniz FMP Berlin Germany Nacho Molina Institute of Genetics and Molecular and Cellular Biology France Nikolai Slavov Northeastern University USA Mikko Taipale University of Toronto Canada Chris Tape University College London Cancer Institute UK Celine Vallot Institut Curie France Alexander van Oudenaarden Hubrecht Institute The Netherlands Xiaowei Zhuang Harvard University USA Scientific organisers Lacramioara Bintu Stanford University USA Hartland Jackson Lunenfeld Tanenbaum Research Institute Canada Arnaud Krebs EMBL Heidelberg Germany Tineke Lenstra Netherlands Cancer Institute Netherlands Mikhail Savitski EMBL Heidelberg Germany Conference organiser Inna B sselmann EMBL Heidelberg Germany Programme Are you on social media Post using EMBLOmics and don t forget to tag EMBLEvents Please note that the programme is subject to change Some speakers may need to join virtually to give their talk For registered participants recorded talks will be accessible on demand for 2 weeks after the end of the event unless indicated otherwise Day 1 Tuesday 19 November Time Europe Berlin Session12 00 13 30Registration and light refreshments13 30 13 45Opening remarks by Scientific Organisers13 45 17 45Systems to function Segment 1Chairs Mikhail Savitski EMBL Heidelberg GermanyArnaud Krebs EMBL Heidelberg Germany13 45 14 15Dynamics and mechanisms of bifunctional transcriptional effectors in human cellsLacramioara Bintu Stanford University USA14 15 14 30Interspecies interactions between the nematode Pristionchus pacificus and bacterial food sources reveal candidate pathways regulating gene expression behaviour and survivalMarina Athanasouli Max Planck Institute for Biology T bingen Germany14 30 14 45The genetic architecture of the human SH3 domain interaction networkSebastian Jaaks Kraatz Friedrich Miescher Institute for Biomedical Research Switzerland14 45 15 15Programming the epigenome to dissect context dependent chromatin functionJames Hackett EMBL Rome Italy15 15 15 30Widespread position dependent transcriptional regulatory sequences in plantsYoav Voichek Gregor Mendel Institute GMI Austrian Academy of Sciences Vienna BioCenter VBC Austria15 30 15 45Widespread chromatin context dependencies of DNA double strand break repair proteinsXabier Vergara Netherlands Cancer Institute The Netherlands15 45 16 15Coffee break and meet the speakers16 15 16 45Protein mis localization in human diseaseMikko Taipale University of Toronto Canada16 45 17 00Spatial reconstruction of single cell enhancer activity in a developing embryoYad Ghavi Helm Ecole Normale Sup rieure of Lyon Institute of Functional Genomics of Lyon IGFL FranceNot available on demand17 00 17 30Interrogation of subcellular processes through RNA and protein interactionKathryn Lilley University of Cambridge UKvirtual speaker17 30 17 45Mapping Genotype to Phenotype Landscapes in Human CellsAbdelghani Mazouzi Netherlands Cancer Institute The NetherlandsNot available on demand17 45 18 45Panel discussion Bridging fields in career and scienceModerator Lacramioara Bintu Stanford University USAPanel speakers Mo Khalil Boston University USAKathryn Lilley University of Cambridge UKMikko Taipale University of Toronto CanadaAlexander van Oudenaarden Hubrecht Institute The NetherlandsXiaowei Zhuang tbc Harvard University USA18 45 20 15Dinner in EMBL Canteen20 15 21 15EMBL Pub Quiz20 15 22 00After dinner drinks in ATC Rooftop lounge Day 2 Wednesday 20 November Time Europe Berlin Session09 00 12 30Systems to function Segment 2Chairs Mikko Taipale University of Toronto CanadaYad Ghavi Helm Ecole Normale Sup rieure of Lyon Institute of Functional Genomics of Lyon IGFL France09 00 09 30Novel sequencing tools to explore translation in individual cellsAlexander Van Oudenaarden Hubrecht Institute The Netherlands09 30 09 45A parsimonious mechanism to generate rhythmic gene expression with wide peak phase dispersionHelge Grosshans Friedrich Miescher Institute for Biomedical Research SwitzerlandNot available on demand09 45 10 00Developmental gene expression patterns driven by synthetic gene regulatory domainsDaniel Murad Ibrahim Berlin Institute of Health Max Planck Institute for Molecular Genetics Germany10 00 10 30Coffee break and meet the speakers10 30 11 00Building structural and spatial interactomes by cross linking mass spectrometryFan Liu Leibniz Institute FMP Berlin Germany11 00 11 30Synthetic reconstitution of complex cellular behaviorMo Khalil Boston University USANot available on demand11 30 11 45A genetic interaction map for a human cell lineMaximilian Billmann University of Bonn University Hospital Bonn GermanyNot available on demand11 45 12 00SPIDR a multiplexed method for mapping RNA Protein interactions reveals a mechanism of translational suppression in cellular stressMarko Jovanovic Columbia University USA12 00 12 30Transcription factor exchange enables prolonged transcriptional burstsTineke Lenstra Netherlands Cancer Institute The NetherlandsEMBO Young Investigator Lecture12 30 13 15Hike in the woods12 30 14 00Lunch14 00 16 00Systems to molecular mechanism Segment 1Chairs Arnaud Krebs EMBL Heidelberg GermanyMarko Jovanovic Columbia University USA14 00 14 30Discovering quantitative rules of enhancer promoter communication with large numbers of artificial regulatory landscapesLuca Giorgetti FMI Basel Switzerland14 30 14 45A phage protein kinase subverts bacterial defense systems through promiscuous phosphorylationTara Bartolec EMBL Heidelberg Germany14 45 15 00Probing DNA damage sites in living cells reveals novel DNA damage response factorsRichard Cardoso da Silva Utrecht University The NetherlandsNot available on demand15 00 15 15Functional maps of a genomic locus reveal confinement of an enhancer by its target geneChristine Moene Netherlands Cancer Institute Oncode Institute The Netherlands15 15 15 30Mechano transduction via membrane potential for growth controlMarkus Basan Harvard Medical School USA15 30 16 00Friend or foe exploring the regulatory role of transposons in early mammalian developmentJoanna Jachowicz IMBA Vienna Austria16 00 16 30Coffee break16 00 18 00Poster Session 1 odd numbers 18 00 19 30Dinner in EMBL Canteen19 30 21 00After dinner drinks in ATC Rooftop lounge Day 3 Thursday 21 November Time Europe Berlin Session09 00 12 45Systems to molecular mechanism Segment 2Chairs Lacramioara Bintu Stanford University USACeline Vallot Institut Curie France09 00 09 30Spatially resolved single cell genomics cell atlas of the brainXiaowei Zhuang Harvard University USANot available on demand09 30 09 45Mammalian promoters are characterised by low frequency of occupancy and high turnover of RNA polymerase IIKasit Chatsirisupachai EMBL Heidelberg Germany09 45 10 00Chromatin dependent motif syntax defines differentiation trajectoriesSevi Durdu Friedrich Miescher Institute for Biomedical Research Germany10 00 10 30Dynamics of microcompartment formation at the mitosis to G1 transitionAnders Sejr Hansen MIT Biological Engineering USA10 30 11 00Coffee break and meet the speakers11 00 11 30Parsing human pancreatic cancers to identify localized tumour stroma and immune environmentsHartland Jackson Lunenfeld Tanenbaum Research Institute CanadaNot available on demand11 30 11 45Scaling laws of human transcriptional activityJiayin Hong University of Cambridge United Kingdom11 45 12 00Single molecule chromatin configurations link transcription factor binding to expression in human cellsJulia Schaepe Stanford University USA12 00 12 30Using proximity dependent biotinylation to understand dynamic cell organization Anne Claude Gingras University of Toronto Canada12 30 14 15Lunch14 15 17 45Systems to disease Segment 1Chairs Tineke Lenstra Netherlands Cancer Institute The NetherlandsAnders Sejr Hansen MIT Biological Engineering USA14 15 14 45Single cell phenoscaping of tumour microenvironment organoidsChris Tape University College London UK14 45 15 00Network based framework for studying etiology and phenotype diversity in ciliopathiesEllen Aarts ETH Zurich Switzerland15 00 15 15Quantitative analysis of developmental timing in whole embryosMichael Dorrity EMBL Heidelberg Germany15 15 15 45Breast cancer epigenomics at single cell resolutionCeline Vallot Institut Curie France15 45 16 15Coffee break and meet the speakers16 15 18 15Poster session 2 even numbers 18 15 20 15Conference dinner in EMBL Canteen20 15 23 45Conference party with DJ in Foyer Day 4 Friday 22 November Time Europe Berlin Session09 30 12 15Systems to disease Segment 2Chairs Hartland Jackson Lunenfeld Tanenbaum Research Institute CanadaMikhail Savitski EMBL Heidelberg Germany09 30 10 00Transcriptional condensates in health and diseaseDenes Hnisz MPI Molecular Genetics Germany10 00 10 15Following transcription complex assembly over timeNils Eickhoff Netherlands Cancer Institute The Netherlands10 15 10 30Automated live cell single molecule imaging reveals the molecular dynamics of Sox9 during differentiation and a proliferative state transition in intestinal organoidsNike Walther University of California Berkeley USANot available on demand10 30 11 00Coffee break and meet the speakers11 00 11 30Unraveling spatio temporal regulation of gene expression during the cell cycle through integration of single cell data and biophysics informed deep learningNacho Molina Institute of Genetics and Molecular and Cellular Biology IGBMC France11 30 12 00From proteome variation across single cells to molecular mechanismsNicolai Slavov Northeastern University USA12 00 12 15Poster prize and closing remarks12 15 13 00Packed lunch and departure13 00Conference shuttle to the Main station and hotelsBus to Frankfurt am Main airport Terminal 1 tickets are available at the registration desk Practical information Registration fees and abstract submission Registration On site registration fees include admission conference materials COVID 19 safety measures meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses On site Academia 550On site PhD Student 350On site Industry 750On site EMBL staff press 300Virtual Academia 200Virtual PhD Student 150Virtual Industry 275 Virtual registration fees include access to all of the talks live streamed and on demand and facility to submit questions NO visa support letters will be issued until payment of the registration fee is confirmed Accredited journalists may be eligible to register for complimentary press registration Registrants may be required to provide accreditation or equivalent proof of press membership after registration Please contact Inna B sselmann for more information Please note that we do not offer complimentary registrations for editors of scientific journals Confirmation and payment Registration will be on a first come first served basis Your place can only be confirmed after payment of the registration fee If you are added to our waiting list please consider taking advantage of our offerings to participate virtually On site participants Types of payments accepted are international bank transfers and credit card payments Virtual participants We are only able to accept card payments In exceptional cases we can accept bank transfers Please contact events embl de for details Abstract submission Only registered participants attending the on site event are eligible to submit an abstract Abstracts will not be accepted from virtual participants After you have logged in and successfully registered you will receive an email asking you to submit your abstract Click on the link provided and enter your abstract in the text box provided Alternatively you can submit your abstract by clicking on the link on the confirmation page directly after registering The same login credentials are used for both processes Please note Title The title should not exceed 20 words Only the first word of the title should start with a capital letter and the rest of the title should be in lowercase Authors and affiliations Please fill in the author s details as requested in the online form The compulsory details are First Name Last Name Organisation Name Affiliation or Company Country and Email Mark only one author as the role of First author and please don t forget to indicate who will be presenting The order of the authors will be listed as follows First Author Co First Author alphabetically if multiple co author s in the order added by the submitter Presentation types When submitting your abstract you can apply for an oral or poster presentation A selection process will take place with the results announced 2 3 weeks after the abstract submission deadline Please check our FAQs pages for further information on how to submit an abstract Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of both registration fee waivers and travel grants Availability is limited to participants attending on site events in Heidelberg and will be indicated during the abstract or motivation letter submission process Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course or conference Travel grant The travel grant will cover the cost of travel airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Course EMBL Conference or EMBO EMBL Symposium from within Europe up to 1000 for participants travelling to an EMBL Course EMBL Conference or EMBO EMBL Symposium from outside Europe up to 500 for any participant travelling to an EMBO Practical Course or EMBO Workshop up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Practical Course or EMBO Workshop Registration fees are only covered for EMBO Practical Courses or EMBO WorkshopsThe organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant EMBO practical courses and workshops only For EMBO Practical Course or EMBO Workshop participants with children there is the possibility to apply for a childcare grant to offset child care costs incurred by participants or speakers when participating at a course or conference Eligible costs include fees for a baby sitter or child care facility travel costs for a care giver or travel costs for taking the child to the meeting etc Please note that priority will be given to early stage researchers A maximum amount of 500 EUR can be awarded per participant applying for an EMBO Childcare Grant In order to apply for this grant for EMBO Workshops you must be registered by the abstract submission deadline Application You may apply for financial assistance when submitting your motivation letter for courses and abstract for conferences In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Selection The scientific organisers will select the recipients of all financial assistance during the motivation letter or abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection is based on your current work or study location the reasons for needing financial support and the impact this event will have on your career Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details View our list of external funding opportunities and information on attending a conference as an event reporter For further information about financial assistance please refer to the FAQ page Accommodation and travel Accommodation is not included in the conference registration fee As further changes in our events are possible due to COVID 19 you should book flights trains and hotels with flexible options and favourable cancellation conditions The hotels below have rooms on hold for participants until 18 October 2024 in some cases at special rates Please quote the booking code OMX24 01 and confirm the exact price of the room with the hotel directly Hotel AnlageHotel ibis HeidelbergHotel MonptiHotel Bayrischer Hof ISG Hotel Staycity Aparthotel HeidelbergB B HotelLeonardo Hotel Heidelberg City CentreHilton HeidelbergExzellenz Hotel Meininger Heidelberg Travel information For travel information please see here If you are travelling to the conference within Germany then you are eligible for the Deutsche Bahn Event Ticket called the Veranstaltungsticket in German This will result in a lower ticket price if your travel distance to Heidelberg is more than 100 km You need to provide proof of your event attendance when purchasing the ticket For more information in English see here or in German see here You can book your ticket here Conference shuttle buses Conference shuttle buses are free of charge for participants and depart from designated bus stops near the hotels to EMBL and back mornings and evenings Download the conference bus schedule here The bus stops for this conference are Staycity Aparthotel Speyerer Str 7 Kurf rsten Anlage opposite Main Train Station Premier Inn Hotel Kurf rsten Anlage 23 Leonardo Hotel City Centre Bergheimer Str 63 Neckarm nzplatz Heidelberg Tourist Information Peterskirche Bus stop Hans B ckler Stra e Bus stop near Rohrbacher Str 22 ISG Hotel View Conference shuttle bus stops and hotels in a larger map Please note that not every bus stop will be used for every event Further details Address EMBL Meyerhofstra e 1 69117 Heidelberg Germany For more information about accommodation and travel please refer to the FAQ page On site information Catering All meals and coffee breaks are included in the registration fee Our catering staff will prepare a wide variety of vegetarian meals meat and fish dishes soups pasta fresh fruit and vegetables as well as a variety of desserts Please wear your badge at all times when serving yourself No food or drinks are allowed in the auditorium Charging lockers There are lockers available next to the stairs leading down into the Auditorium You will find some of those equipped with sockets to charge your smartphone tablet etc Electricity and charging station In most places the electricity is 220 volts AC 50 cycles An adaptor and a plug that fits the German socket may be needed for your appliances laptop i e American Japanese etc A USB charging station for electronic devices is available at the registration desk EMBL merchandise If you are interested in purchasing EMBL merchandise products presented in the glass display in the registration area please email the EMBL shop to place an order or get in contact with your Course Organiser Kindly note the EMBL shop is only open upon request and all purchases must be made in cash Euros only Health and safety notes Please read EMBL s COVID 19 safety policy for on site events Do not smoke in any EMBL building Eating and drinking is prohibited in the Auditorium and all laboratories Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required The first aid room is located next to the ATC Registration Desk room 10 205 Dial the Emergency number 222 from any EMBL internal phone only Where is the accident What happened How many injured Emergency number 06221 387 7821 from mobile phones Please report all accidents to the conference officer at the registration desk In case of fire Press the nearest fire alarm button or the Emergency number 222 from any internal phone A loud fire alarm will go off if an evacuation is required On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting points Do not use the lifts Beyond first aid Please remember to bring your own medication if needed to the conference Note that the next pharmacy is a 4 minute drive from the EMBL but for many medications you will be required to see a doctor to get a prescription Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg In any case the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary Internet Wi Fi is available everywhere on the premises no password required just log on to ATC Guest The eduroam network secure world wide roaming access service developed for the international research and education community is also available Lost and found Lost and Found are kept at the registration desk until the end of the conference Luggage There are lockers available on site to store your luggage which require a 2 EURO coin to operate There is another luggage room on level E0 which is free to use but remains unlocked during the conference Nursing room There is a nursing room available in the ATC Rooftop Lounge on level A29 Photography During the conference an EMBL Photographer may be taking photographs If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Printing We can help printing your boarding passes train ticket Please send it to events embl de and collect your print outs at the registration desk Room for prayer yoga and meditation There is a room for prayer mediation and yoga located on level E0 behind the Auditorium Please be respectful of other participants using the room Sightseeing A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing Travel to and from the venue During the event we provide conference shuttle buses to and from EMBL In addition there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time Information on the conference shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page Useful German expressions EnglishGermanHelloHalloGoodbyeAuf WiedersehenGood morningGuten MorgenGood afternoonGuten TagGood eveningGuten AbendGood nightGute NachtI m sorryTut mir leidExcuse me Entschuldigen SieHow are you Wie geht s I m fine thanks And you Mir geht es gut danke und dir Ihnen What is your nameWie heisst du Wie heissen Sie My name isIch heisseDo you speak EnglishSprechen Sie Englisch I don t understandIch verstehe nichtPlease speak more slowlyK nnen Sie bitte langsamer sprechenThank youDanke sch nWhere is the toilet Wo ist die Toilette Please call me a taxiBitte rufen Sie mir ein TaxiHow do I get to Wie komme ich zum zur A beer two beers pleaseEin Bier zwei Bier bitteA glass of red white wine pleaseEin Glas Rot Weisswein bitteThe menu pleaseDie Speisekarte bitteIs there a local speciality Gibt es eine Spezialit t aus dieser Gegend I m VegetarianIch bin VegetarierIt was deliciousEs war hervorragendThe bill pleaseDie Rechnung bitteI have a headacheIch habe KopfschmerzenI have a sore throatIch habe HalsschmerzenMy stomach hurtsIch habe MagenschmerzenI m allergic toIch bin allergisch gegenI need a doctor who speaks EnglishGibt es einen Arzt der Englisch spricht Virtual participation What s included Access to all the livestreamed talks Video library of the recorded talks during the event and for two weeks afterwards Please note at the request of individual speakers some talks are not recorded Facility to submit questions Please note that only on site participants are able to submit abstracts and participate in the poster sessions Event platform We are using an event platform for this conference More information about the platform will be shared ahead of the conference Guidelines Do not broadcast the conference to unregistered participants You are encouraged to tweet and post about the event Tweet unless the speaker specifically says otherwise but be mindful of unpublished data Please do not capture transmit or redistribute data presented at the meeting Additional information can be found in our Code of Conduct Health and well being It is important to stay healthy and move around especially when you are attending an event virtually We have put together a few coffee break stretches and yoga videos in the conference platform for you to enjoy during the event How to ask questions Please use the Q A function in the event platform If you have any other questions you can go to the Help Desk in the event platform Click on more on the top menu and click Help Desk Time zone The programme is planned based on the Europe Berlin time zone unless otherwise stated Please take your time zone into consideration when planning your attendance Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page COVID 19 related questions COVID 19 information for on site events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Event sponsor Bronze sponsor Media partners International Union of Biochemistry and Molecular Biology Molecular Systems Biology an EMBO Press Journal Medinformatics a Bon View Publishing journal Open Biology a Royal Society journal Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information on sponsoring possibilities If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9 Leaderboard 729 90...

Lacramioara Bintu, Hartland Jackson, Arnaud Krebs, Tineke Lenstra, Mikhail Savitski

EMBL Conference

EMBL Heidelberg, Virtual

18 November - 22 November 2024

Plant genomes: from data to discovery

Edit

November 18, 2024 00:002024CourseVirtual

Description This course will take you through a selection of genomic tools and open resources to help you explore plant genomes and answer biological questions Covering a range of omics data including genomic proteomic and imaging data this course will show you where to find relevant data and how to use publicly available tools to connect across resources supporting plant genomic data driven knowledge discovery Throughout the course you will address essential questions such as How can genomic data inform crop breeding strategies Which genetic variations contribute to plant resilience in changing environments How can proteomics enhance agricultural productivity The course instructors will guide you on how to navigate the different resources efficiently You will be shown how to submit your sequence to a public archive explore gene related information and variants within specific genes You will investigate functional conservation and expression patterns within gene families explore protein functional information as well as plant derived metabolomics and lipidomics data and analyse gene expression data Virtual courseParticipants will learn via a mix of pre recorded lectures live presentations and trainer Q A sessions Practical experience will be developed through trainer led computational exercises Live sessions will be delivered using Zoom with additional support and asynchronous communication via Slack Computational practicals will run using online tools meaning participants will not require access to a powerful computer or install complex software on their own machines In the week before the course there will be a brief induction session Participants will need to be available between the hours of 09 00 17 00 GMT each day of the course Trainers will be available to assist answer questions and provide further explanations during these times...

Barbara Etzi

Virtual

18 November - 22 November 2024

Edit

November 13, 2024 15:302024WebinarVirtual

Description MGnify is EMBL EBI s microbiome data resource which enables the analysis and exploration of metagenomic metatranscriptomic amplicon and assembly data This webinar will showcase the recently released MGnify Proteins website which provides information regarding the proteins identified through MGnify s analysis pipeline In MGnify Proteins the information about proteins are accompanied by metadata such as underlying biological domains and encountered environments The protein sequence data is further utilised in other MGnify resources such as MGnifams to generate protein families models and structures...

Virtual

6 November 2024

A guide to Job Dispatcher sequence analysis tools and programmatic access

Edit

November 06, 2024 15:302024WebinarVirtual

Description The Job Dispatcher at EMBL EBI provides free access to a variety of bioinformatics tools and biological datasets via web and programmatic interfaces This webinar will provide a comprehensive guide on navigating various sequence analysis tools EMBOSS Clustal Omega NCBI BLAST etc and showcase the newest updates to the website It will also demonstrate how to access these tools programmatically...

Virtual

5 November - 8 November 2024

DNA replication: from basic biology to disease

Edit

November 05, 2024 00:002024ConferenceEMBL Heidelberg, Virtual

Description OverviewSpeakersProgrammePractical informationSponsorsAboutMedia Kit Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Symposium overview There has been tremendous progress in the past few years regarding our understanding of DNA replication in eukaryotes both yeast and mammals Many important questions in the field are poised to be answered within the next decade These include understanding DNA replication at the biochemical and three dimensional protein structure levels In addition studies using high throughput technologies at the cellular and organismal levels are poised to answer how accurate replication of the genome is ensured by controlling origin firing in space and time Session topics Replisome structure Origin selection licensing and firing Chromatin replication Replication stress and fork stability Replication in cancer etiology and treatment opportunities Speakers Keynote speakers John Diffley The Francis Crick Institute UK Bik Tye Professor emeritus at Cornell University USA Speakers Naama Barkai Weizmann Institute of Science Israel Sara Buonomo The University of Edinburgh UK Karlene Cimprich Stanford University USA Alessandro Costa The Francis Crick Institute UK Vincenzo Costanzo The FIRC Institute of Molecular Oncology Italy Nynke Dekker University of Oxford UK Olivier Hyrien Institut de Biologie de l cole Normale Sup rieure France Qing Li Peking University China Massimo Lopes Institute of Molecular Cancer Research Switzerland Kyungjae Myung Ulsan National Institute of Science and Technology South Korea Jan Michael Peters Research Institute of Molecular Pathology IMP Austria Agata Smogorzewska The Rockefeller University USA Julian Stingele Gene Center and Department of Biochemistry Ludwig Maximilians Universit t M nchen Germany Nitika Taneja Erasmus University Medical Center The Netherlands Scientific organisers Anja Groth University of Copenhagen Denmark Thanos Halazonetis Universit de Gen ve Switzerland Helle Ulrich Institute of Molecular Biology GmbH Germany Conference organiser Charlotte Courtney Course and Conference Officer EMBL Heidelberg Germany Programme Are you on social media Post using EESReplication and don t forget to tag EMBLEvents Please note that the programme is subject to change Some speakers may need to join virtually to give their talk For registered participants recorded talks will be accessible on demand for 2 weeks after the end of the event unless indicated otherwise Day 1 Tuesday 5 November 2024 Timings Europe CET Speaker12 00 13 30Registration and light refreshments13 30 13 45Opening remarksAnja Groth13 45 17 30Session 1 Replisome structureChairs Anja Groth and Christian Speck13 45 14 45Keynote lecture Four decades of eukaryotic DNA replication from yeast genetics to cryoEM structures of the replisomeBik Tye Professor emeritus at Cornell University USA14 45 15 15Non canonical ATR signaling extends replicationfork slowing and remodelling to undamaged nuclear regions via NBS1 phosphorylationMassimo Lopes Institute of Molecular Cancer Research SwitzerlandNot available on demand15 15 15 30Multiple mechanisms for licensing human replication originsFranziska Bleichert Yale University USA15 30 15 45Principles of yeast and human DNA licensingMaximillian Reuter Imperial College London UK15 45 16 30Coffee Break and Meet the speakersBik Tye Keynote Professor emeritus at Cornell University USAMassimo Lopes Institute of Molecular Cancer Research Switzerland16 30 17 00Structural studies on the eukaryotic replisomeAlessandro Costa The Francis Crick Institute UK17 00 17 15How is the Replicative DNA Helicase Activated in Metazoa Insights from Single Molecule Studies Gheorghe Chistol Stanford University USANot available on demand17 15 17 30A molecular trigger for replication fork collapseCameron McClymont The Francis Crick Institute UK17 30 17 45DNA Replication origin usage and the 3D genomeMarcel M chali CNRS University of Montpellier FranceNot available on demand17 45 19 15 Meet the speakers dinner in the canteen Speakers allocated to each table19 15 20 45Parallel social options Pub Quiz in the Canteen19 15 22 00Parallel social options Networking drinks in the ATC rooftop lounge Day 2 Wednesday 6 November 2024 Timings Europe CET Speaker08 30 09 00Arrival and coffee09 00 12 00Session 2 Origin selection licensing and firingChairs Mirit Aladjem and Nick Rhind09 00 09 30How ORC recognises its genomic binding sitesNaama Barkai Weizmann Institute of Science Israel09 30 09 45Mapping of DNA replication origins in vivo highlights mechanisms of genome stability and agingGiacomo Rossetti University of Geneva Switzerland09 45 10 00PCNA loading during leading strand synthesis in the budding yeast replisomeEmma Fletcher MRC Laboratory of Molecular Biology UK10 00 10 30Coffee Break and Meet the speakersAlessandro Costa The Francis Crick Institute UKNaama Barkai Weizmann Institute of Science Israel10 30 11 00Nanopore sequencing studies of budding yeast and human genome replicationOlivier Hyrien Institut de Biologie de l cole Normale Sup rieure FranceNot available on demand11 00 11 15Dual DNA replication modes Varying fork speeds and initiation rates within the spatial replication program in XenopusKathrin Marheineke Paris Cit University France11 15 11 45Single molecule studies of DNA replicationNynke Dekker TU Delft Netherlands11 45 12 00The natural paucity of KIAA0101 PAF15 rate limits PCNA dynamics during unperturbed DNA replicationKumar Somyajit University of Southern Denmark Denmark12 00 13 30Lunch and Meet the Editors 30min at the end of lunch Kerstin Brachhold Advanced Biology Wiley GermanyJuanita Perera FEBS Letters GermanyNele Hug Nature Communications UKJuanita Perera FEBS Letters GermanyEsther Schnapp EMBO Reports GermanyHartmut Vodermaier The EMBO Journal Germany13 30 17 30Session 3 Chromatin replicationEva Petermann and Boris Pfander13 30 14 00How to rebuild heterochromatin after DNA replication and the mitotic tsunami Sara Buonomo The University of Edinburgh UK14 00 14 15Mechanism of de novo chromatin assembly during DNA replicationFrancesca Mattiroli Hubrecht Institute The Netherlands14 15 14 30Establishment Of DNA Replication Programs In The Early EmbryoJason Halliwell The University of Copenhagen Denmark14 30 15 00Mechanisms of Chromatin Reorganization underReplication StressNitika Taneja Erasmus University Medical Center NetherlandsNot available on demand15 00 15 30Coffee Break and Meet the speakersOlivier Hyrien Institut de Biologie de l cole Normale Sup rieure FranceNynke Dekker TU Delft NetherlandsSara Buonomo The University of Edinburgh UKNitika Taneja Erasmus University Medical Center Netherlands15 30 16 00Nucleosome Assembly Epigenetic Inheritance and BeyondQing Li Peking University China16 00 16 15Chromatin replication as a modulator of transcriptional activityCristina Gonz lez Aguilera CABIMER CSIC Spain16 15 16 30The fork protection complex promotes parental histone recycling and epigenetic memoryValentin Flury Max Planck Institute of Immunobiology and Epigenetics Germany16 30 17 00Cohesin mediated DNA loop extrusionJan Michael Peters Research Institute of Molecular Pathology IMP Austria17 00 17 30Flash talks for poster session 145 Yohan An47 Agos Bertolin53 Ammar Danazumi55 Isabel D ez59 Martina Muste Sadurni61 Samson Glaser63 Bennie Lemmens67 Kristi Jensen69 Tom Kache70 Itamar Simon71 Manami Katoh75 Leonie Kollenstart81 Luke Lynch85 Peter Martin89 J r me Poli95 Simone Pelliciari99 Michalis Petropoulos105 Corrado Santocanale109 Nick Rhind111 Koyel Roy119 Diala Shatleh Rantisi129 Marcell Veiner133 Florian Weissmann135 Bart Westendorp137 Ronald Wong141 Hemendra Yadav143 Eman Zaffar145 Masato Kanemaki17 30 19 30Poster Session 1 odd numbers with beer and snacks19 30 21 00Dinner in the canteen21 00 22 30Networking drinks in the ATC rooftop lounge Day 3 Thursday 7 November 2024 Timings Europe CET Speaker09 00 12 30Session 4 Replication stress and fork stabilityMorning chairs Bennie Lemmens and Vincent Pag s08 30 09 00Arrival and coffee09 00 09 30The causes and consequences of replication stressKarlene Cimprich Stanford University USANot available on demand09 30 09 45Fanconi anemia and DNA damage tolerance pathways collaborate during mitotic DNA synthesisAnja Bielinsky University of Virginia USA09 45 10 00Branching of polyubiquitin chains acts as a timing device to orchestrate ubiquitin signalling in the DNA damage bypass pathwayKirill Petriukov Institute of Molecular Biology Germany10 00 10 45Coffee Break and Meet the speakersQing Li Peking University ChinaJan Michael Peters Research Institute of Molecular Pathology IMP AustriaKarlene Cimprich Stanford University USA10 45 11 15Understanding causes and consequences of DNA replication stress in vertebratesVincenzo Costanzo the FIRC Institute of Molecular Oncology Italy11 15 11 30Timing transition region fragile sites in neural progenitor cellsPei Chi Wei German Cancer Research Center DKFZ Germany11 30 12 00Mechanism of replication coupled DNA protein crosslink repairJulian Stingele Ludwig Maximilians Universit t M nchen GermanyNot available on demand12 00 12 15Things fall apart Mechanism of cell cycle arrest by hydroxyureaGrant Schauer Colorado State University USA12 15 12 30Disparate requirements for RAD54L in replication fork reversalMollie Uhrig Colorado State University USA12 30 14 45Lunch14 45 17 15Session 4 Replication stress and fork stabilityAfternoon chairs Thanos Halazonetis and Masato Kanemaki14 45 15 00The DNA replication checkpoint targets the kinetochore to allow relocation of collapsed forks to the nuclear peripheryCatherine Freudenreich Tufts University USA15 00 15 15Single cell multi omic DNA replication sequencing methods uncover DNA replication fork speed dynamics and their regulatorsJeroen van den Berg Hubrecht Institute The Netherlands15 15 15 30Profiling replication fork dynamics with multiplexed TrAEL seqJon Houseley Babraham Institute UK15 30 16 15Coffee Break and Meet the speakersVincenzo Costanzo the FIRC Institute of Molecular Oncology ItalyJulian Stingele Ludwig Maximilians Universit t M nchen Germany16 15 16 30TTF2 promotes mitotic activation of the replisome associated E3 ubiquitin ligase TRAIPGeylani Can Harvard Medical School USA16 30 16 45TTF2 drives mitotic replisome disassembly and MiDAS by coupling the TRAIP ubiquitin ligase to Pol EpsilonKarim Labib University of Dundee UK16 45 17 15Flash talks for poster session 244 Mirit Aladjem46 Benjamin Pardo48 Berta Canal50 Mathilde Courtes54 Brendon Davis66 Gal Jaschek68 Daphne Jurriens72 Eva Petermann74 Ariel Klavaris78 Innesa Leonovich80 Zhaowei Liu86 Vincent Pag s90 Bel n G mez Gonz lez92 Harry Orrin100 Florian Pflug102 Sunil Kumar Pradhan104 Romain Forey120 Chaonan Shi127 Bruno Uri n Gonz lez128 Sidrit Uruci130 Karim Labib134 Marcel Werner140 Anoop Kumar Yadav142 Yue Yao17 15 19 15Poster Session 2 even numbers with beer and snacks19 15 20 45Conference gala dinner in the canteen20 45 00 00Party with DJ Jens in the ATC Foyer and the ATC Rooftop Lounge Day 4 Friday 8 November 2024 Timings Europe CET Speaker09 00 13 00Session 5 Replication in cancer etiology and treatment opportunitiesChairs Helle Ulrich08 30 09 00Arrival and coffee09 00 09 30Investigation and translation of molecular mechanisms for genomic integrity Kyungjae Myung Ulsan National Institute of Science and Technology South Korea09 30 09 45Tissue specificity of human DNA replication origins revealed by strand bias switches in cancer genome mutationsMarina Salvadores Ferreiro University of Copenhagen Denmark09 45 10 00Unravelling the dynamics of single cell DNA replication timing through machine learning reveals a further layer of heterogeneity in cancer progressionChunlong Chen Institut Curie France10 00 10 30RTF2 and replication dynamicsAgata Smogorzewska The Rockefeller University USA10 30 11 30Coffee Break and Meet the speakersKyungjae Myung Ulsan National Institute of Science and Technology South KoreaAgata Smogorzewska The Rockefeller University USAJohn Diffley Key note The Francis Crick Institute UK11 30 11 45DNA sequence motifs link somatic mutagenesis to histone binding at potential DNA replication termination sitesAnna Poetsch Technische Universit t Dresden Germany11 45 12 00Impaired nucleotide metabolism due to p53 deficiency leads to replication stress and triggers a cascade of events that initiates chromothripsisAur lie Ernst German Cancer Research Center DKFZ Germany12 00 13 00Keynote lecture Biochemical approaches to understanding chromosome replicationJohn Diffley The Francis Crick Institute UK13 00 13 15Closing Remarks Thanos HalazonetisPoster Prize AnnouncementsAnja Groth and Helle Ulrich13 15 13 30Packed Lunch and departure13 30Airport shuttle leaves EMBL for Frankfurt Am Main International airport Practical information Registration fees and abstract submission On site registration fees include admission conference materials meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Virtual registration fees include access to all of the talks livestreamed and on demand and facility to submit questions On site PhD Student 625On site Academia 725On site Industry 925On site Journal Editor 300Virtual PhD Student 175Virtual Academia 225Virtual Industry 275 Editors from scientific journals are allowed to attend at a reduced rate but asked to contribute to the conference in return by taking part in meet the editors sessions or other planned activities within the programme A letter to support your visa application will be issued on request once payment of the registration fee is confirmed We recommend that you book your visa appointment as soon as possible to avoid any delay with your visa application Accredited journalists may be eligible to register for complimentary press registration Registrants may be required to provide accreditation or equivalent proof of press membership after registration Please contact charlotte courtney embl org for more information Please note that we do not offer complimentary registrations for editors of scientific journals Confirmation and payment Registration will be on a first come first served basis Your place can only be confirmed after payment of the registration fee If you are added to our waiting list please consider taking advantage of our offerings to participate virtually On site participants Types of payments accepted are international bank transfers and credit card payments Virtual participants We are only able to accept card payments In exceptional cases we can accept bank transfers Please contact events embl de for details Abstract submission Only participants registering to attend the on site event are eligible to submit an abstract Abstracts will not be accepted from virtual participants After registration you can submit your abstract via a separate link that will be provided in the email confirmation Alternatively you can access the link on the confirmation page directly after registering The same login credentials are used for both processes Please note Abstract body The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised Title The title should not exceed 20 words Only the first word of the title should start with a capital letter and the rest should be lowercase Authors and affiliations Please fill in the author s details as requested in the online form The compulsory fields are First Name Last Name Organisation Name Affiliation or Company Country and Email Kindly mark only one author in the role of First Author and please don t forget to indicate who will be the Presenter Please enter your co authors correctly via the system by adding accounts together with their organisation institute Do not copy paste them into the body of the abstract text as they will not be indexed in the abstract book Presentation types When submitting your abstract you can apply for an oral or poster presentation A selection process will take place with the results announced 2 3 weeks after the abstract submission deadline For detailed instructions on how to submit a conference abstract follow the instructions provided in this video Please check our FAQs pages for further information on how to submit an abstract Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of registration fee waivers travel grants and childcare grants Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course or conference Travel grant The travel grant will cover the cost of travel to an on site event airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from within Europe up to 1000 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from outside Europe up to 500 for any participant travelling to an EMBO Workshop up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Workshop up to 700 for any participant working in Croatia Czech Republic Estonia Greece Hungary Italy Lithuania Luxembourg Poland Slovenia and Turkey travelling to an EMBO Workshop Registration fees are only covered for EMBO Workshops The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant There is the possibility to apply for a childcare grant to offset child care costs incurred by participants speakers and organisers when attending a conference Eligible costs include but are not limited to fees for a baby sitter or child care facility and travel costs for a caregiver Please note that priority will be given to early stage researchers In order to apply for this grant you must be registered by the abstract submission deadline There is a limited amount of funding available for the childcare grants and funds will be distributed amongst eligible applicants Application On site participants You may apply for financial assistance when submitting your abstract In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Virtual participants If you are attending virtually you can apply for financial assistance in the submission portal by the abstract deadline Read the instructions on how to apply for financial assistance Only submissions for financial assistance will be accepted Presentation abstracts cannot be submitted here and will be declined In your application you will be asked to summarise your current work answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Selection The scientific organisers will select the recipients of all financial assistance during the abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection for registration fee waivers and travel grants is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Childcare grants will be allocated in the same timeframe 6 8 weeks before the event start date Please note that priority will be given to early stage researchers Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details View our list of external funding opportunities and information on attending a conference as an event reporter For further information about financial assistance please refer to the FAQ page Accommodation and travel Accommodation is not included in the conference registration fee As further changes in our events are possible you should book flights trains and hotels with flexible options and favourable cancellation conditions The hotels below have rooms on hold for participants until Tuesday 8 October 2024 in some cases at special rates Please email the hotel directly quoting the booking code EES24 12 to confirm the exact price of the room Hotel AnlageHotel ibis HeidelbergPremier Inn Heidelberg CityHotel Bayrischer Hof ISG Hotel Staycity Aparthotel HeidelbergB B HotelLeonardo Hotel Heidelberg City CentreSteffi s Hostel HeidelbergExzellenz HotelMeininger HeidelbergHotel Vier Jahreszeiten HeidelbergHotel Holl nder Hof Hotel MonptiHilton Heidelberg Travel information For travel information please see here If you are travelling to the conference within Germany then you are eligible for the Deutsche Bahn Event Ticket called the Veranstaltungsticket in German This will result in a lower ticket price if your travel distance to Heidelberg is more than 100 km You need to provide proof of your event attendance when purchasing the ticket For more information in English see here or in German see here You can book your ticket here Conference shuttle buses Here is the Conference shuttle bus timetable Conference shuttle buses are free of charge for participants and depart from designated bus stops near the hotels to EMBL and back mornings and evenings The bus stops for this conference are Hotel Staycity Speyerer Str 7 Kurf rsten Anlage Opposite Main Train Station Hotel Premier Kurf rsten Anlage 23 Leonardo Hotel Heidelberg City Center Bergheimer Str 63 Neckarmuenzplatz Heidelberg Tourist Information Peterskirche Bus stop Hans B ckler Stra e Bus stop Rohrbacher Str 22 ISG Hotel Im Eichwald 19 View Conference shuttle bus stops and hotels in a larger map Please note that not every bus stop will be used for every event Further details Address EMBL Meyerhofstra e 1 69117 Heidelberg Germany For more information about accommodation and travel please refer to the FAQ page Onsite information Catering All meals and coffee breaks are included in the registration fee Our catering staff will prepare a wide variety of vegetarian meals meat and fish dishes soups pasta fresh fruit and vegetables as well as a variety of desserts Please wear your badge at all times when serving yourself No food or drinks are allowed in the auditorium Charging lockers There are lockers available next to the stairs leading down into the Auditorium You will find some of those equipped with sockets to charge your smartphone tablet etc Electricity and charging station In most places the electricity is 220 volts AC 50 cycles An adaptor and a plug that fits the German socket may be needed for your appliances laptop i e American Japanese etc A USB charging station for electronic devices is available at the registration desk EMBL merchandise If you are interested in purchasing EMBL merchandise products presented in the glass display in the registration area please email the EMBL shop to place an order or get in contact with your Course Organiser Kindly note the EMBL shop is only open upon request and all purchases must be made in cash Euros only Health and safety notes Please read EMBL s COVID 19 safety policy for on site events Do not smoke in any EMBL building Eating and drinking is prohibited in the Auditorium and all laboratories Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required The first aid room is located next to the ATC Registration Desk room 10 205 Dial the Emergency number 222 from any EMBL internal phone only Where is the accident What happened How many injured Emergency number 06221 387 7821 from mobile phones Please report all accidents to the conference officer at the registration desk In case of fire Press the nearest fire alarm button or the Emergency number 222 from any internal phone A loud fire alarm will go off if an evacuation is required On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting points Do not use the lifts Beyond first aid Please remember to bring your own medication if needed to the conference Note that the next pharmacy is a 4 minute drive from the EMBL but for many medications you will be required to see a doctor to get a prescription Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg In any case the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary Internet Wi Fi is available on campus using the EMBL Events network and the event specific password which will be provided on site The eduroam network secure worldwide roaming access service developed for the international research and education community is also available Lost and found Lost and Found items are kept at the registration desk until the end of the conference Luggage There are lockers available on site to store your luggage which require a 2 EURO coin to operate There is another luggage room on level E0 which is free to use but remains unlocked during the conference Nursing room There is a nursing room available in the ATC Rooftop Lounge on level A29 Photography During the conference an EMBL Photographer may be taking photos If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Printing We can help to print your boarding pass train ticket Please send it to events embl de and collect your print outs at the registration desk Room for prayer yoga and meditation There is a room for prayer meditation and yoga located on level E0 behind the Auditorium Please be respectful of others using the room Sightseeing A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing Travel to and from the venue During the event we provide conference shuttle buses to and from EMBL In addition there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time Information on the conference shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page Useful German expressions HelloHalloGoodbyeAuf Wiedersehen formal Tsch ss informal Good morningGuten MorgenGood afternoonGuten TagGood eveningGuten AbendGood nightGute NachtI m sorryEs tut mir leidExcuse me Entschuldigen Sie How are you Wie gehts I m fine thanks And you Mir geht es gut danke Und dir Ihnen What is your nameWie hei en Sie formal Wie hei t du informal My name is Ich hei e Do you speak English Sprechen Sie Englisch I don t understandIch verstehe nichtPlease speak more slowlyK nnen Sie bitte langsamer sprechenThank youDankesch nWhere is the toilet Wo ist die Toilette Please call me a taxiBitte rufen Sie mir ein TaxiHow do I get to Wie komme ich zum zur A beer two beers pleaseEin Bier zwei Bier bitteA glass of red white wine pleaseEin Glas Rot Wei wein bitteThe menu pleaseDie Speisekarte bitteIs there a local speciality Gibt es eine Spezialit t aus dieser Gegend I m vegetarianIch bin VegetarierIt was deliciousEs war hervorragendThe bill pleaseDie Rechnung bitteI have a headacheIch habe KopfschmerzenI have a sore throatIch habe HalsschmerzenMy stomach hurtsIch habe MagenschmerzenI m allergic toIch bin allergisch gegenI need a doctor who speaks English Ich brauche einen Arzt der Englisch spricht Virtual participation What s included Access to all the livestreamed talks Video library of the recorded talks during the event and for two weeks afterwards Please note at the request of individual speakers some talks are not recorded Facility to submit questions Talks will only be recorded upon speaker s consent Please note that only on site participants are able to submit abstracts and participate in the poster sessions Event platform We are using an event platform for this conference More information about the platform will be shared ahead of the conference Guidelines Do not broadcast the conference to unregistered participants You are encouraged to tweet and post about the event Tweet unless the speaker specifically says otherwise but be mindful of unpublished data Please do not capture transmit or redistribute data presented at the meeting Additional information can be found in our Code of Conduct Health and well being It is important to stay healthy and move around especially when you are attending an event virtually We have put together a few coffee break stretches and yoga videos in the conference platform for you to enjoy during the event How to ask questions Please use the Q A function in the event platform If you have any other questions you can go to the Help Desk in the event platform Click on more on the top menu and click Help Desk Time zone The programme is planned based on the Europe Berlin time zone unless otherwise stated Please take your time zone into consideration when planning your attendance Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for participants page COVID 19 related questions COVID 19 information for onsite events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Event supporter Media partners Advanced Biology a Wiley Journal Advanced Genetics a Wiley Journal BioEssays a Wiley Journal ChemBioChem a Wiley Journal EMBO Journal an EMBO Press Journal FEBS Letters Genes and Development a Cold Spring Harbor Journal Genome Research a Cold Spring Harbor Journal International Union of Biochemistry and Molecular Biology Journal of Molecuar Biology an Elsevier Journal Medinformatics a Bon View Publishing journal Open Biology a Royal Society journal Wiley Journals Advanced Genetics Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de About EMBO EMBL Symposia promote scientific communication and collaboration in the European research area They provide scientists with a platform to discuss and exchange ideas on forward looking topics and new developments in the life sciences Topics emphasise upcoming developments and the interdisciplinary nature of related fields Jointly funded and organised by EMBO and EMBL and complementary to their respective courses workshops and conference programmes the symposia promote scientific communication and collaboration All symposia are held in the EMBL Advanced Training Centre ATC in Heidelberg Germany or virtually Media Kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9 Leaderboard 728 90...

Anja Groth, Thanos Halazonetis, Helle Ulrich

EMBO | EMBL Symposium

EMBL Heidelberg, Virtual

4 November - 8 November 2024

Structural bioinformatics

Edit

November 04, 2024 00:002024CourseVirtual

Description This course provides a guide to the commonly used methods and tools in structural bioinformatics to analyse and interpret experimentally determined and AI predicted macromolecular structure data Structural biology determining the three dimensional shapes of biomacromolecules and their complexes can tell us a lot about how these molecules function and the roles they play within a cell Data derived from structure determination experiments and Artificial Intelligence AI assisted structure prediction enables life science researchers to address a wide variety of questions This course explores bioinformatics data resources and tools for the investigation analysis and interpretation of both experimentally determined and predicted biomacromolecular structures It will focus on how best to analyse and interpret available structural data to gain useful information given specific research contexts The course content will also cover predicting function and exploring interactions with other macromolecules Successful participants may be sent materials prior to the course These might include pre recorded talks and required reading or online training that will be essential to fully engage with the course...

Juanita Riveros

Virtual

4 November - 8 November 2024

The fundamentals of high-end cell sorting

Edit

November 04, 2024 00:002024CourseEMBL Heidelberg

Description OverviewSpeakersPreliminary programmePractical informationSponsorsMedia kit Overview Course overview This course includes a robust theoretical part on the fundamentals of cell sorting delivered by world leading experts and practical sessions on using standard cuvette sorters In addition the course program will include principles applications and hands on sessions on Image Cell Sorting ICS allowing attendees to get in touch with this exciting technology Audience The course is intended for Ph D students and postdocs who are starting to use or already using cell sorting in their research projects Applicants with previous active knowledge of basic principles of flow cytometry and regular use of flow cytometers in daily research will profit most from the course content Modules Resources The topics that will be covered include instrument set up and validation correct operation to avoid technical insufficiency sample quality the essentials of gating performing single cell sorts for sequencing and sorting based on morphological traits Learning Outcomes The principle objectives are to deliver the theory of cell sorting and the practical sides of this high end technology What past participants say about the course I am amazed by how inspirational and educational this practical course was People from all over the world joined and together we had a great week learning more about a topic all of us are passionate about Alexandra Vujkovic Institute of Tropical Medicine Belgium Even though the samples I work with are very different from what was demonstrated in the practical I left with many useful techniques not easily found in literature if at all The environment was very lively and the trainers were very eager to answer our questions and feed our curiosity G Y Grace Ho Max Planck Institute for Marine Microbiology Germany This course tought me not only the basics of cell sorting but also a plethora of factors and caveats influencing the outcome of my experiments I feel prepared and confident Tomasz Kaszubowski Universit tsklinikum Erlangen Germany Please see EMBL s COVID 19 safety recommendations for testing and other requirements to attend this on site course Speakers Speakers trainers and staff Jochen Behrends Research Center Borstel Leibniz Lung Center Germany Derek Davies Cytometry UK Gelo dela Cruz Novo Nordisk Foundation Center for Stem Cell Medicine reNEW Denmark Mark Dessing BD Germany Claudia Dumrese University of Zurich Switzerland Marcus Eich German Cancer Research Center DKFZ Germany Daniel Gimenes EMBL Heidelberg Germany Christopher Hall Babraham Institute UK Desiree Kunkel BIH at Charit Universit tsmedizin Berlin Germany Sophie Novault Institut Pasteur France Diana Ordonez EMBL Heidelberg Germany Beata Ramasz EMBL Heidelberg Germany Marta Rodriguez EMBL Heidelberg Germany Steffen Schmitt German Cancer Research Center DKFZ Germany Moritz Winker EMBL Heidelberg Germany Scientific organisers Diana Ordonez EMBL Heidelberg Germany Malte Paulsen Novo Nordisk Foundation Center for Stem Cell Medicine reNEW Denmark Beata Ramasz EMBL Heidelberg Germany Steffen Schmitt German Cancer Research Center DKFZ Germany Event organisers Maria Bacadare Course and Conference Team Lead EMBL Heidelberg Germany Swetlana Krez Scientific Training Officer EMBL Heidelberg Germany Preliminary programme Are you on social media Post using EMBOCellSort and don t forget to tag EMBLEvents Some pre course work such as watching pre recordings protocol reading and computational exercises with estimated time 0 10 hours will be required and will be shared in advance of the course Some speakers may need to join virtually to give their lecture or Q A and the programme is subject to change Please note the below programme is still subject to changes Day 1 Monday 4 November 2024 Time Europe Berlin SpeakerLocation08 40 08 55Bus from hotel to EMBL ATC EntranceISG Hotel09 00 09 30Welcome and house notes and course overviewBeata Ramasz EMBL Heidelberg GermanyFlex Lab A B09 30 10 30Ice breaker activityAll participants and speakers trainersFlex Lab A B10 30 11 00Coffee BreakFlex Lab A B11 00 12 30Flash talksAll participants and speakers trainersFlex Lab A B12 30 13 30LunchEMBL Canteen13 30 14 15Lecture Fluidics Optics and Signal GenerationGelo dela Cruz Novo Nordisk Foundation Center for Stem Cell Medicine reNEW DenmarkFlex Lab A B14 15 15 00Lecture Streams Nozzles Deflections and DropsDaniel Gimenes EMBL Heidelberg GermanyFlex Lab A B15 00 16 30Discussion session share topics of interest open questionsAll participants and speakers trainersTraining Lab A B16 30 17 00Coffee BreakFlex Lab A B17 00 17 45Lecture The essentials of gating the impact of sample qualityBeata Ramasz EMBL Heidelberg GermanyFlex Lab A B17 45 18 30Lecture Considering downstream applications into your sortingJochen Behrends Research Center Borstel Leibniz Lung Center GermanyFlex Lab A B18 30 20 00DinnerATC Rooftop Lounge20 00Departure to HotelATC Entrance Day 2 Tuesday 5 November 2024 Time Europe Berlin SpeakerLocation08 40 08 55Bus from hotel to EMBL ATC EntranceISG Hotel09 00 09 10Overview of the dayFlex Lab A B09 10 09 55Lecture Biosafety ConsiderationsSteffen Schmitt DKFZ GermanyFlex Lab A B09 55 10 40Lecture Conventional vs Spectral Flow CytometrySophie Novault Institut Pasteur FranceFlex Lab A B10 40 11 00Coffee breakFlex Lab A B11 00 11 45Lecture Image based Cell SortingMark Dessing BD GermanyFlex Lab A B11 45 12 30Lecture Imaging applications in real lifeMarta Rodriguez EMBL Heidelberg GermanyMoritz Winker EMBL Heidelberg GermanyFlex Lab A B12 30 13 30LunchEMBL Canteen13 30 16 00Discussion session share topics of interest open questionsAll participants and speakers trainersFlex Lab A B16 00 16 30Coffee BreakFlex Lab A B16 30 17 15Lecture How to choose a sorter Claudia Dumrese University of Zurich SwitzerlandFlex Lab A B17 15 18 00Lecture Best analysis toolsChristopher Hall Babraham Institute UKFlex Lab A B18 00 18 45Departure to downtownATC Entrance18 45Dinner downtown Day 3 Wednesday 6 November 2024 Time Europe Berlin SpeakerLocation08 20 08 55Bus from hotel to EMBL ATC Entrance and to DKFZISG Hotel09 00 09 10Overview of the dayFlex Lab A B09 10 10 40Practical Session 2 Running Different Sorter TypesGroup 1 DKFZ Fusion AGroup 2 DKFZ Discover AGroup 3 EMBL Fusion AGroup 4 EMBL Discover AAll speakers trainersDKFZEMBL10 40 11 10Coffee breakFlex Lab A B11 10 12 40Continue Practical Session 2 Running Different Sorter TypesGroup 1 DKFZ Fusion AGroup 2 DKFZ Discover AGroup 3 EMBL Fusion AGroup 4 EMBL Discover AAll speakers trainersDKFZEMBL12 40 13 40LunchEMBL DKFZ Canteen13 40 15 30Practical Session 3 Running Different Sorter TypesGroup 1 DKFZ Fusion BGroup 2 DKFZ Discover BGroup 3 EMBL Fusion BGroup 4 EMBL Discover BAll speakers trainersDKFZEMBL15 30 16 00Coffee breakFlex Lab A B16 00 18 00Continue Practical Session 3 Running Different Sorter TypesGroup 1 DKFZ Fusion BGroup 2 DKFZ Discover BGroup 3 EMBL Fusion BGroup 4 EMBL Discover BAll speakers trainers DKFZEMBL18 00Departure to ISG Hotel DowntownATC Entrance18 00Free evening Day 4 Thursday 7 November 2024 Time Europe Berlin SpeakerLocation08 20 08 55Bus from hotel to EMBL ATC Entrance and to DKFZ ISG Hotel09 00 09 10Overview of the dayFlex Lab A B09 10 10 40Practical Session 4 Running Different Sorter TypesGroup 1 EMBL Discover AGroup 2 EMBL Fusion AGroup 3 DKFZ Discover AGroup 4 DKFZ Fusion AAll speakers trainersEMBLDKFZ10 40 11 10Coffee breakFlex Lab A B11 10 12 40Continue Practical Session 4 Running Different Sorter TypesGroup 1 EMBL Discover AGroup 2 EMBL Fusion AGroup 3 DKFZ Discover AGroup 4 DKFZ Fusion AAll speakers trainersEMBLDKFZ12 40 13 40LunchEMBL DKFZ Canteen13 40 15 30Practical Session 5 Running Different Sorter TypesGroup 1 EMBL Discover BGroup 2 EMBL Fusion BGroup 3 DKFZ Discover BGroup 4 DKFZ Fusion BAll speakers trainersEMBLDKFZ15 30 16 00Coffee breakFlex Lab A B16 00 18 00Continue Practical Session 5 Running Different Sorter TypesGroup 1 EMBL Discover BGroup 2 EMBL Fusion BGroup 3 DKFZ Discover BGroup 4 DKFZ Fusion BAll speakers trainersEMBLDKFZ18 00 18 30Departure to ISG Hotel DowntownATC Entrance18 30Dinner and bowling Day 5 Friday 8 November 2024 Time Europe Berlin SpeakerLocation08 40 08 55Bus from hotel to EMBL ATC EntranceISG Hotel09 00 09 10Overview of the dayFlex Lab A B09 10 09 55Lecture Best practicesD sir e Kunkel BIH at Charit Universit tsmedizin Berlin GermanyFlex Lab A B09 55 10 40Lecture Tips for publishing high quality cytometry dataDerek Davies Cytometry UKFlex Lab A B10 40 11 10Coffee BreakFlex Lab A B11 10 12 40Interactive discussion session Troubleshooting tips and tricksBeata Ramasz EMBL Heidelberg GermanyDiana Ordonez EMBL Heidelberg GermanyFlex Lab A B12 40 13 40LunchEMBL Canteen13 40 14 40Feedback and discussionFlex Lab A B14 40Departure to Heidelberg Train Station and DowntownEMBL Bus Stop ATC Entrance Practical information Registration fees and motivation letter The course is limited to 16 participants For selection purposes please note that your application will not be considered without a letter of motivation Registration This EMBO course includes accommodation and transportation to and from the ISG Hotel to the venue Academia 500PhD Student 500Industry 1000 A letter to support your visa application will be issued on request once payment of the registration fee is confirmed We recommend that you book your visa appointment as soon as possible to avoid any delay with your visa application Confirmation and payment The registration fee should be paid only after acceptance to the course The results will be announced approximately 2 3 weeks after the application deadline Motivation letter submission After you have logged in and successfully registered you will receive an email asking you to submit your motivation letter Click on the link provided and enter your motivation letter in the text box provided Alternatively you can submit your motivation letter by clicking on the link on the confirmation page directly after registering Instructions Include your relevant skills experience and qualifications showing why you would be suitable for the course Explain why you would like to attend including what you can contribute and how you think you will benefit from the course Please note The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised For detailed instructions please watch our video on how to submit a course motivation letter Further details For further information about registration and motivation letter submission please refer to the FAQ page Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of registration fee waivers travel grants and childcare grants Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course Travel grant The travel grant will cover the cost of travel airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Course within Europe up to 1000 for participants travelling to an EMBL Course from outside Europe up to 500 for any participant travelling to an EMBO Practical Course up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Practical Course up to 700 for any participant working in Croatia Czech Republic Estonia Greece Hungary Italy Lithuania Luxembourg Poland Slovenia and Turkey travelling to an EMBO Practical Course Registration fees are only covered for EMBO Practical Courses The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant There is the possibility to apply for a childcare grant to offset child care costs incurred by participants speakers trainers and organisers when attending a course Eligible costs include but are not limited to fees for a babysitter or child care facility and travel costs for a caregiver Please note that priority will be given to early stage researchers There is a limited amount of funding available for the childcare grants and funds will be distributed amongst eligible applicants Boehringer Ingelheim Fonds travel grant Applies to selected courses only Availability will be indicated during the motivation letter submission process This grant covers costs related to your attendance at the course registration travel and accommodation costs The grant is restricted to PhD students and postdocs who conduct basic biomedical research Whether you are eligible to apply for a travel grant depends on when you received your university entrance qualification e g Abitur A Levels High School Diploma Final State Examination for PhD and MD students as well as graduates the university entrance qualification must not have been obtained more than 11 years ago at the time of the envisaged course for postdocs the university entrance qualification must not have been obtained more than 13 years ago at the time of the envisaged course Application You may apply for financial assistance when submitting your motivation letter for courses In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application For the Boehringer Ingelheim Fonds Travel Grant there is a pre application question during the motivation letter submission process and if selected you will be requested to complete a standard form and documentation consisting of your travel expense estimation Selection The scientific organisers will select the recipients of registration fee waivers and travel grants during the motivation letter or abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection for registration fee waivers and travel grants is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Childcare grants will be allocated in the same timeframe 6 8 weeks before the event start date Please note that priority will be given to early stage researchers Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details See our list of external funding opportunities and for further information about financial assistance please refer to the FAQ page Accommodation and travel Travel information For travel information please see here If you are travelling to the conference within Germany then you are eligible for the Deutsche Bahn Event Ticket called the Veranstaltungsticket in German This will result in a lower ticket price if your travel distance to Heidelberg is more than 100 km You need to provide proof of your event attendance when purchasing the ticket For more information in English see here or in German see here You can book your ticket here Hotel Accommodation in single rooms including breakfast is included in the registration fee Accommodation has been booked for you at the ISG Hotel for the default dates of Sunday 3 to Friday 8 November 5 nights Any additional nights need to be booked and paid for by you We recommend that all course participants stay at the ISG Hotel which is the dedicated hotel for the course Local transport Shuttle buses will go from the ISG Hotel to EMBL and back mornings and evenings A bus schedule and location of the bus stops will be made available prior to the meeting Further details Address EMBL Heidelberg Meyerhofstra e 1 69117 Heidelberg GermanyFor more information about accommodation and travel please refer to the FAQ page On site information Catering All meals and coffee breaks are included in the registration fee Our catering staff will prepare a wide variety of vegetarian meals meat and fish dishes soups pasta fresh fruit and vegetables as well as a variety of desserts Please wear your badge at all times when serving yourself No food or drinks are allowed in the laboratories Electricity and charging station In most places the electricity is 220 volts AC 50 cycles An adaptor and a plug that fits the German socket may be needed for your appliances laptop i e American Japanese etc A USB charging station for electronic devices is available at the registration desk EMBL Merchandise If you are interested in purchasing EMBL merchandise products presented in the glass display in the registration area please email the EMBL shop to place an order or get in contact with your Course Organiser Kindly note the EMBL shop is only open upon request and all purchases must be made in cash Euros only Health and safety notes Please read EMBL s COVID 19 safety policy for on site events Do not smoke in any EMBL building Eating and drinking is prohibited in all laboratories Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required The first aid room is located next to the ATC Registration Desk room 10 205 Dial the Emergency number 222 from any EMBL internal phone only Where is the accident What happened How many injured Emergency number 06221 387 7821 from mobile phones Please report all accidents to the conference officer at the registration desk In case of fire Press the nearest fire alarm button or the Emergency number 222 from any internal phone A loud fire alarm will go off if an evacuation is required On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting points Do not use the lifts Beyond first aid Please remember to bring your own medication if needed to the conference Note that the next pharmacy is a 4 minute drive from the EMBL but for many medications you will be required to see a doctor to get a prescription Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg In any case the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary Internet Wi Fi is available on campus Log in using the EMBL Events network and the event specific password which will be provided on site The eduroam network secure worldwide roaming access service developed for the international research and education community is also available Lost and found Lost and Found items are kept at the registration desk until the end of the conference Luggage There are lockers available on site to store your luggage which require a 2 EURO coin to operate There is another luggage room on level E0 which is free to use but remains unlocked during the conference Nursing room There is a nursing room available in the ATC Rooftop Lounge on level A29 Photography During the conference an EMBL Photographer may be taking photos If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Printing We can help to print your boarding pass train ticket Please send it to events embl de and collect your print outs at the registration desk Room for prayer yoga and meditation There is a room for prayer meditation and yoga located on level E0 behind the Auditorium Please be respectful of others using the room Sightseeing A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing Travel to and from the venue During the event we provide conference shuttle buses to and from EMBL In addition there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time Information on the shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page Map to walk from ISG Hotel to EMBL Additional information Address EMBL Heidelberg Meyerhofstra e 1 69117 Heidelberg Germany ATC orientation map Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page Event software Event software The EMBL eCampus learning platform will be used to collaborate communicate and network with all of the course participants All participants will receive information on how to join shortly before the course We recommend using Chrome Safari or Mozilla Firefox browsers for eCampus Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page COVID 19 related questions COVID 19 information for on site events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Event Sponsor Event Supporter Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other events or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9...

Beata Ramasz, Diana Ordonez

EMBO Practical Course

EMBL Heidelberg

31 October 2024

Programmatic access to UniProt using Python

Edit

October 31, 2024 15:002024WebinarVirtual

Description UniProt is a comprehensive expert led publicly available database of protein sequence function and variation information This webinar will give an overview of programmatic access to the UniProt database using Python and cover key aspects of protein entry searches data filtering batch downloads and give examples of further processing of downloaded target data Following a brief introduction to UniProt services where to find relevant documentation and help features the webinar will focus on worked examples These will include how to programmatically search and retrieve protein entries and sequences within the results we will then show how to align orthologous sequences and filter for features of interest The webinar will also cover programmatic examples of the UniProt ID mapping service batch downloads filtering and processing data You can also access the Google Colab used during the webinar...

Virtual

29 October - 31 October 2024

Managing a bioinformatics core facility

Edit

October 29, 2024 00:002024CourseEMBL-EBI

Description This knowledge exchange workshop is an opportunity for managers of bioinformatics core facilities to learn from EMBL EBI s service teams and from each other These facilities play an essential role in enabling research in the life sciences The landscape is constantly evolving as new research tools emerge as experiments become increasingly data intensive and as their users experimental researchers become more exposed to the power of data driven biology This course will allow participants to share experiences discuss challenges and solutions that they face and plan ways to cope with the ever changing demands raised by the molecular life science field It will include sessions to learn from bioinformatics service providers hear how others have tackled common problems and work together to design core services resource them and measure their impact A limited number or travel bursaries are available Please see the Additional information tab for conditions...

Barbara Etzi

EMBL-EBI

23 October 2024

I made my code open - now what? Steps to a thriving open software project

Edit

October 23, 2024 15:302024WebinarVirtual

Description Sharing your code is a good first step towards building open source software but it is not enough to ensure its success This webinar focuses on practical issues to increase impact of open software projects including maintenance community building discoverability project management documentation licensing and user needs Our speakers will share their experience working with the open source code as part of the CAPITAL project open source tool that uses machine learning to identify biological concepts from text and link them to relevant ontologies They will discuss the challenges they have encountered and potential solutions to address these...

Virtual

21 October - 26 October 2024

Imaging down to single-molecule resolution: STED & MINFLUX nanoscopy

Edit

October 21, 2024 00:002024CourseEMBL Heidelberg

Description OverviewSpeakers trainers and staffProgrammePractical informationSponsorsMedia kit Overview Course overview The aim of the course is to train microscopy users in different super resolution microscopy methods Stimulated Emission Depletion STED and MINFLUX nanoscopy Both techniques overcome the diffraction limit of light with the help of a donut shaped laser beam thereby achieving resolutions that are impossible with conventional light microscopy The course combines scientific lectures by experienced researchers from the super resolution field with hands on sessions at the different super resolution microscopes and in the laboratory Participants will gain a technical understanding of the methods as well as an overview of different application fields and imaging techniques sample preparation and data handling for both STED and MINFLUX After the course participants can choose the right approach for their experimental needs and perform their experiments on a STED or MINFLUX microscope Audience Aimed at early stage researchers e g pre or post doctoral level in the life sciences with access to STED and MINFLUX super resolution microscopy facilities and at imaging facility staff involved in training and supporting scientists using STED and MINFLUX super resolution microscopy Participants should have an immediate need to apply these techniques The course will have a strong emphasis on the practical know how needed to exploit the latest developments in STED and MINFLUX microscopy It is therefore equally suited to scientists who are already using super resolution microscopy in their research and to researchers using advanced imaging techniques who wish to improve their practical knowledge Modules Theory and applications of STED and MINFLUX microscopy Sample preparation for STED and MINFLUX super resolution imaging 2D and 3D STED imaging as well as multicolour live cell tissue and fluorescence lifetime STED imaging 2D and 3D MINFLUX imaging MINFLUX tracking STED and MINFLUX microscopy data handling Learning outcome At the end of the course participants will be able to plan an experiment using STED and MINFLUX super resolution microscopy prepare their own samples accordingly acquire images using optimal conditions and settings and analyse them using appropriate methods and tools Please see EMBL s COVID 19 safety recommendations for testing and other requirements to attend this on site course Speakers trainers and staff Speakers trainers and staff Francesca Bottanelli Freie Universit t Berlin Germany Alexander Carsten University Hospital Hamburg Eppendorf Germany Jan Ellenberg EMBL Heidelberg Germany Stefan Hell Max Planck Institute for Biophysical Chemistry Germany Jan Maximilian Janssen Johannes Kepler Universit t Linz Austria Rohan Kapoor Universit t G ttingen Germany Grazvydas Lukinavicius Max Planck Institute for Multidisciplinary Sciences Germany Raphael Mercier Max Planck Institute for Plant Breeding Research Germany Francesca Pennacchietti KTH Royal Institute of Technology Sweden Jonas Ries University of Vienna Austria Carmen Rodilla Freie Universit t Berlin Germany Arina Rybina EMBL Heidelberg Germany Till Stephan Max Planck Institute for Multidisciplinary Sciences Germany Rifka Vlijm University of Groningen The Netherlands Kruno Vuku i Ru er Bo kovi Institute Croatia Scientific organisers Clara G rth Abberior Instruments Germany Charlotte Kaplan Bioquant Universit t Heidelberg Germany Marko Lampe EMBL Heidelberg Germany Ulf Matti Abberior Instruments Germany Julia Menzel Abberior Instruments Germany Sebastian Schnorrenberg EMBL Heidelberg Germany Course organisers Swetlana Krez Scientific Training Officer EMBL Heidelberg Germany Karoline Wolkersdorfer Course and Conference Officer EMBL Heidelberg Germany Programme Are you on social media Post using EMBLSTED MINFLUX and don t forget to tag EMBLEvents Some speakers may need to join virtually to give their lecture or Q A and the programme is subject to change Day 1 Monday 21 October 2024 TimeDescriptionLocation08 40Bus from ISG to EMBL Imaging CenterISG Hotel09 00 09 30Welcome and house notes incl safety Imaging Center Lecture Hall09 30 10 00Course overviewImaging Center Lecture Hall10 00 11 00Lecture 1 Overview of Super resolution TechniquesMarko Lampe DKFZ Heidelberg Germany Sebastian Schnorrenberg EMBL Heidelberg GermanyImaging Center Lecture Hall11 00 11 30Coffee BreakImaging Center Lecture Hall11 30 12 15Lecture 2 What limits meiotic crossovers remote Raphael Mercier Max Planck Institute for Plant Breeding Research GermanyImaging Center Lecture Hall12 15 13 15LunchCanteen13 15 14 15Introduction round 1Imaging Center Lecture Hall14 15 14 30Coffee breakImaging Center Lecture Hall14 30 15 30Lecture 3 Imaging the molecular processes of cell division across scalesJan Ellenberg EMBL Heidelberg GermanyImaging Center Lecture Hall15 30 15 45Coffee breakImaging Center Lecture Hall15 45 16 30Lecture 4 MINFLUX for dynamic structural cell biology remote Jonas Ries University of Vienna AustriaImaging Center Lecture Hall16 30 19 00Practical 1Imaging Center Labs19 00 20 00DinnerCanteen20 00Departure to ISGATC Bus Stop Day 2 Tuesday 22 October 2024 TimeDescriptionLocation08 40Bus from ISG to EMBL Imaging CenterISG Hotel09 00 09 05Overview of the dayImaging Center Lecture Hall09 05 09 50Lecture 5 Unravelling the inner secrets of cells with gene editing and live cell STED microscopy remote Fran Botanelli Freie Universit t Berlin GermanyImaging Center Lecture Hall09 50 10 00Coffee BreakImaging Center Lecture Hall10 00 12 15Introduction round 2Imaging Center Lecture Hall12 15 13 30LunchCanteen13 30 16 00Practical 2Imaging Center Labs16 00 16 30Coffee BreakImaging Center Lecture Hall16 30 19 00Practical 3Imaging Center Labs19 00 20 00DinnerCanteen20 00Departure to ISGATC Bus Stop Day 3 Wednesday 23 October 2024 TimeDescriptionLocation09 30Bus from ISG to EMBL Imaging CenterISG Hotel09 45 09 50Overview of the dayImaging Center Lecture Hall09 50 10 35Lecture 7 Sharpening the focus STED microscopy in unveiling the mysteries of mitotic spindles across speciesKruno Vuku i Ru er Bo kovi Institute CroatiaImaging Center Lecture Hall10 35 11 15Coffee BreakImaging Center Lecture Hall11 15 12 00Lecture 8 Optimal STED from archaea to human cells remote Rifka Vlijm University of Groningen The NetherlandsImaging Center Lecture Hall12 00 12 30Lecture 9 Euro BioImaging ERIC Opportunities for open access to state of the art imaging expertise and technologiesMarianna Childress Poli EMBL Heidelberg GermanyImaging Center Lecture Hall12 30 13 30LunchCanteen13 30 16 00Practical 4Imaging Center Labs16 00 16 30Coffee BreakImaging Center Lecture Hall16 30 19 00Practical 5Imaging Center Labs19 00 20 00DinnerCanteen20 00Departure to ISGATC Bus Stop Day 4 Thursday 24 October 2024 TimeDescriptionLocation08 40Bus from ISG to EMBL Imaging CenterISG Hotel09 00 09 05Overview of the dayImaging Center Lecture Hall09 05 09 50Lecture 10 A niche within the niche Connexins at the AISJan Maximilian Janssen Johannes Kepler University Linz AustriaImaging Center Lecture Hall09 50 10 00Coffee BreakImaging Center Lecture Hall10 00 12 30Practical 6Imaging Center Labs12 30 13 30LunchCanteen13 30 16 00Practical 7Imaging Center Labs16 10Departure to Heidelberg downtown via ISG HotelATC Bus stop17 00 21 00Course dinner and bowling downtown at FirebowlHeidelberg downtown Day 5 Friday 25 October 2024 TimeDescriptionLocation08 40Bus from ISG to EMBL Imaging CenterISG Hotel09 00 09 05Overview of the dayImaging Center Lecture Hall09 05 09 50Lecture 11 Charting the nanotopography of inner hair cell ribbon synapsesRohan Kapoor Universit t G ttingen GermanyImaging Center Lecture Hall09 50 10 35Lecture 12 Visualizing bacterial infections at the nanoscaleAlexander Carsten Universit tsklinikum Hamburg Eppendorf GermanyImaging Center Lecture Hall10 35 11 00Coffee BreakImaging Center Lecture Hall11 00 11 45Lecture 13 Exploring Photocontrollable Fluorescent Protein for Live Cell Imaging at the NanoscaleFrancesca Pennacchietti KTH Royal Institute of Technology SwedenImaging Center Lecture Hall11 45 12 30Lecture 14 Investigating the structure and dynamics of mitochondria at the nanoscaleTill Stephan Max Planck Institute for Multidisciplinary Sciences GermanyImaging Center Lecture Hall12 30 13 20LunchCanteen13 20 13 30Group photoin front of the Imaging Center13 30 14 30Keynote Lecture 15 Molecule scale resolution and dynamics in fluorescence microscopyStefan Hell Max Planck Institute for Biophysical Chemistry GermanyImaging Center Lecture Hall14 30 16 30Practical 8Imaging Center Labs16 30 16 45Coffee BreakImaging Center Lecture Hall16 45 19 15Practical 9Imaging Center Labs19 15 20 00DinnerCanteen20 00Departure to ISGATC Bus Stop Day 6 Saturday 26 October 2024 TimeDescriptionLocation08 40Bus from ISG to EMBL Imaging CenterISG Hotel09 00 11 30Practical 10Imaging Center Labs11 30 12 30LunchCanteen12 30 15 00Practical 11Imaging Center Labs15 00 16 00Final discussion feedback round and closing remarksImaging Center Lecture Hall16 00Bus to Heidelberg train station via Hilton hotelATC Bus Stop Practical information Registration fees and motivation letter The course is limited to 20 participants For selection purposes please note that your application will not be considered without a letter of motivation Registration Registration fees include admission course materials meals and coffee Participants are expected to book and pay their own accommodation and travel expenses Academia 700PhD Student 700Industry 1250 A letter to support your visa application will be issued on request once payment of the registration fee is confirmed We recommend that you book your visa appointment as soon as possible to avoid any delay with your visa application Confirmation and payment The registration fee should be paid only after acceptance to the course The results will be announced approximately 2 3 weeks after the application deadline Motivation letter submission After you have logged in and successfully registered you will receive an email asking you to submit your motivation letter Click on the link provided and enter your motivation letter in the text box provided Alternatively you can submit your motivation letter by clicking on the link on the confirmation page directly after registering Instructions Include your relevant skills experience and qualifications showing why you would be suitable for the course Explain why you would like to attend including what you can contribute and how you think you will benefit from the course Please note The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised For detailed instructions please watch our video on how to submit a course motivation letter Further details For further information about registration and motivation letter submission please refer to the FAQ page Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of registration fee waivers travel grants and childcare grants Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course Travel grant The travel grant will cover the cost of travel airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Course within Europe up to 1000 for participants travelling to an EMBL Course from outside Europe Registration fees are only covered for EMBO Practical Courses The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant There is the possibility to apply for a childcare grant to offset child care costs incurred by participants speakers trainers and organisers when attending a course Eligible costs include but are not limited to fees for a babysitter or child care facility and travel costs for a caregiver Please note that priority will be given to early stage researchers There is a limited amount of funding available for the childcare grants and funds will be distributed amongst eligible applicants Boehringer Ingelheim Fonds travel grant Applies to selected courses only Availability will be indicated during the motivation letter submission process This grant covers costs related to your attendance at the course registration travel and accommodation costs The grant is restricted to PhD students and postdocs who conduct basic biomedical research Whether you are eligible to apply for a travel grant depends on when you received your university entrance qualification e g Abitur A Levels High School Diploma Final State Examination for PhD and MD students as well as graduates the university entrance qualification must not have been obtained more than 11 years ago at the time of the envisaged course for postdocs the university entrance qualification must not have been obtained more than 13 years ago at the time of the envisaged course Application You may apply for financial assistance when submitting your motivation letter for courses In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application For the Boehringer Ingelheim Fonds Travel Grant there is a pre application question during the motivation letter submission process and if selected you will be requested to complete a standard form and documentation consisting of your travel expense estimation Selection The scientific organisers will select the recipients of registration fee waivers and travel grants during the motivation letter or abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection for registration fee waivers and travel grants is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Childcare grants will be allocated in the same timeframe 6 8 weeks before the event start date Please note that priority will be given to early stage researchers Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details See our list of external funding opportunities and for further information about financial assistance please refer to the FAQ page Accommodation and travel Hotel Accommodation is not included in the registration fee Participants are expected to book and pay for their own accommodation A mix of single and twin rooms have been reserved for 6 nights 20 26 October 2024 at ISG Hotel Single rooms are limited and will be available on a first come first served basis After the selection process selected participants should contact the hotel directly to make a booking with a booking code code of your course EIC24 01 by the deadline of 23 September 2024 We recommend that all course participants stay in the dedicated hotel for the course Travel information For travel information please see here If you are travelling to the conference within Germany then you are eligible for the Deutsche Bahn Event Ticket called the Veranstaltungsticket in German This will result in a lower ticket price if your travel distance to Heidelberg is more than 100 km You need to provide proof of your event attendance when purchasing the ticket For more information in English see here or in German see here You can book your ticket here Local transport Shuttle buses will go from ISG Hotel to EMBL and back mornings and evenings A bus schedule and location of the bus stops will be made available prior to the meeting Further details Address EMBL Heidelberg Meyerhofstra e 1 69117 Heidelberg GermanyFor more information about accommodation and travel please refer to the FAQ page On site information Catering All meals and coffee breaks are included in the registration fee Our catering staff will prepare a wide variety of vegetarian meals meat and fish dishes soups pasta fresh fruit and vegetables as well as a variety of desserts Please wear your badge at all times when serving yourself No food or drinks are allowed in the laboratories Electricity and charging station In most places the electricity is 220 volts AC 50 cycles An adaptor and a plug that fits the German socket may be needed for your appliances laptop i e American Japanese etc A USB charging station for electronic devices is available at the registration desk EMBL Merchandise If you are interested in purchasing EMBL merchandise products presented in the glass display in the registration area please email the EMBL shop to place an order or get in contact with your Course Organiser Kindly note the EMBL shop is only open upon request and all purchases must be made in cash Euros only Health and safety notes Please read EMBL s COVID 19 safety policy for on site events Do not smoke in any EMBL building Eating and drinking is prohibited in all laboratories Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required The first aid room is located next to the ATC Registration Desk room 10 205 Dial the Emergency number 222 from any EMBL internal phone only Where is the accident What happened How many injured Emergency number 06221 387 7821 from mobile phones Please report all accidents to the conference officer at the registration desk In case of fire Press the nearest fire alarm button or the Emergency number 222 from any internal phone A loud fire alarm will go off if an evacuation is required On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting points Do not use the lifts Beyond first aid Please remember to bring your own medication if needed to the conference Note that the next pharmacy is a 4 minute drive from the EMBL but for many medications you will be required to see a doctor to get a prescription Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg In any case the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary Internet Wi Fi is available on campus Log in using the EMBL Events network and the event specific password which will be provided on site The eduroam network secure worldwide roaming access service developed for the international research and education community is also available Lost and found Lost and Found items are kept at the registration desk until the end of the conference Luggage There are lockers available on site to store your luggage which require a 2 EURO coin to operate There is another luggage room on level E0 which is free to use but remains unlocked during the conference Nursing room There is a nursing room available in the ATC Rooftop Lounge on level A29 Photography During the course an EMBL Photographer may be taking photos If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Printing We can help to print your boarding pass train ticket Please send it to events embl de and collect your print outs at the registration desk Room for prayer yoga and meditation There is a room for prayer meditation and yoga located on level E0 behind the Auditorium Please be respectful of others using the room Sightseeing A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing Travel to and from the venue During the event we provide conference shuttle buses to and from EMBL In addition there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time Information on the shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page Map to walk from ISG Hotel to EMBL Additional information Address EMBL Heidelberg Meyerhofstra e 1 69117 Heidelberg Germany ATC orientation map Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page Event software Event software The EMBL eCampus learning platform will be used to collaborate communicate and network with all of the course participants All participants will receive information on how to join shortly before the course We recommend using Chrome Safari or Mozilla Firefox browsers for eCampus Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page COVID 19 related questions COVID 19 information for on site events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Media partners Imaging and Microscopy a Wiley magazine Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other events or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9...

Clara Gürth, Charlotte Kaplan, Marko Lampe, Ulf Matti, Julia Menzel, Sebastian Schnorrenberg

EMBL Course

EMBL Heidelberg

Edit

October 10, 2024 15:002024WebinarVirtual

Virtual

9 October 2024

Visualising integrated single cell and spatial transcriptomics datasets

Edit

October 09, 2024 15:302024WebinarVirtual

Description Spatial transcriptomics is a cutting edge field that has revolutionised our understanding of biological systems by integrating spatial information with transcriptomics technologies WebAtlas is a data pipeline and visualisation platform for integrated single cell and spatial transcriptomic data This webinar will introduce the WebAtlas platform and its collaboration with the BioImage Archive which is a free public archive for the biological imaging data particularly showcasing the importance of open FAIR data and cloud compatible scalable open data formats...

Virtual

8 October - 11 October 2024

Molecular mechanisms in evolution and ecology

Edit

October 08, 2024 00:002024ConferenceEMBL Heidelberg, Virtual

Description OverviewSpeakersProgrammePractical informationSponsorsMedia Kit Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Conference overview Dramatic advances in omics technologies and genetic engineering now enable us to tackle one of biology s most fascinating problems how evolution works in life s communities and ecosystems Gaining mechanistic insights requires bringing together multiple disciplines and viewpoints The focus of this workshop series is on interspecies and cell environment interactions across living organisms with a special focus on bacteria microbial eukaryotes and viruses The workshop series aims to highlight the latest technological advances amplify scientific and societal focus on biodiversity and showcase studies on the vital role of microbes in planetary ecosystems The 2024 meeting will bring together researchers from a wide range of fields and organismal systems that aim to gain mechanistic insights on major outstanding ecological and evolutionary questions e g how organisms interact and assemble into communities how genotypic variation transforms into phenotypic variation or that develop novel experimental and or computational approaches for doing so The meeting will foster dialogue between researchers from different backgrounds that work on diverse ecological systems to catalyze new innovative ideas and aid the career advancement of young researchers Session topics In the wild The genotype phenotype map Coevolution across trophic levels Assembly and evolution of communities Innovative integrative approaches for ecology and evolution What past participants say about the conference An incredibly interesting and well organised event not only from the scientific side but also on the technical part As expected from other editions of the meeting the science was amazing and very variegated Kudos for the organisation and for the unusually high number of young speakers Irene Stefanini University of Turin Italy One of my favourite meetings with a real community feeling I ve started collaborations and made great friends here Rike Stelkens Population Genetics Stockholm University Sweden A great conference and academic environment networking opportunities are limitless Jose Antonio Urban Aragon International Laboratory for Human Genome Research National Autonomous University of Mexico LIIGH UNAM Mexico This event has been granted the following EMBO sustainability badge Grade 2 of 3 Speakers Keynote speakers Harmit Malik Howard Hughes Medical Institute Fred Hutchinson Cancer Center USA Speakers Aude Bernheim Institut Pasteur France Jesse Bloom Howard Hughes Medical Institute Fred Hutchinson Cancer Center USA Virtual speaker Susana Coelho Max Planck Institute for Biology T bingen Germany Vaughn Cooper University of Pittsburgh USA Kat Coyte University of Manchester UK Juan Diaz Colunga Institute of Functional Biology Genomics CSIC University of Salamanca Spain Jordi van Gestel EMBL Heidelberg Germany Paula Goncalves Nova School of Science and Technology Portugal Georg Hochberg Max Planck Institute for Terrestrial Microbiology Germany Nicole King Howard Hughes Medical Institute University of California Berkeley USA Virtual speaker Irene Newton Indiana University USA Clarissa Nobile University of California Merced USA Kiran Patil University of Cambridge UK Markus Ralser Charit University Medicine Germany Antonis Rokas Vanderbilt University USA Hinrich Schulenburg Kiel University Germany Julia Schwartzman University of Southern California USA Sarah Teichmann Cambridge Stem Cell Institute UK Virtual speaker Scientific organisers Gilles Fischer Sorbonne University France Jordi van Gestel EMBL Heidelberg Germany Kimberly Kline University of Geneva Switzerland Sara Mitri University of Lausanne Switzerland Antonis Rokas Vanderbilt University USA Conference organiser Aline Schnieder EMBL Heidelberg Germany Programme Are you on social media Post using EMBOEvoEco and don t forget to tag EMBLEvents Please note that the programme is subject to change Some speakers may need to join virtually to give their talk For registered participants recorded talks will be accessible on demand for 2 weeks after the end of the event unless indicated otherwise Day 1 Tuesday 8 October 2024 Time Europe Berlin Speaker14 30 16 00Registration and coffee16 00 16 15Opening remarks by scientific organisers16 15 17 15Keynote lecture Fitness landscapes in host virus interactionsHarmit Malik Howard Hughes Medical Institute and Fred Hutchinson Cancer Center USASession 1 In the wildSession chair Antonis Rokas Vanderbilt University USA17 15 17 45Tumultuous evolution of a floral yeast clade impact of gene loss and HGT on metabolic adaptationPaula Goncalves Nova School of Science and Technology PortugalNot available on demand17 45 18 15Choanoflagellates introverted or just repressed Nicole King Howard Hughes Medical Institute University of California Berkeley USA virtual speaker 18 15 18 35Mass lysis of bacterial predators drives the enrichment of antibiotic resistance in soil microbial communities Samay Pande Indian Institute of Science IndiaNot available on demand18 35 18 55Gene conversion drives natural product diversification in soil bacteria Aleksandra Nivina University of Zurich Switzerland18 55 20 00Dinner in EMBL Canteen20 00 21 00Pub quiz in EMBL Canteen21 00 22 00Poster session sneak peek with drinks Day 2 Wednesday 9 October 2024 Time Europe Berlin SpeakerSession 1 In the wildSession chair Antonis Rokas Vanderbilt University USA09 00 09 30Evolution in a complex world predator prey interactions in the soil Jordi van Gestel EMBL Heidelberg GermanyNot available on demand09 30 10 00Evolution of reproductive strategies lessons from seaweeds and their virusSusana Coelho Max Planck Institute for Biology T bingen GermanyNot available on demand10 00 10 20Environmental and genetic control of Saccharomyces yeasts mating strategies Chiara Vischioni Centre National de la Recherche Scientifique CNRS IRCAN France10 20 11 00Coffee break and meet the speakers11 00 11 20The life cycle of natural budding yeast polyploidsCintia G mez Mu oz Sorbonne Universit France11 20 11 40Unraveling the molecular mechanisms behind multicellularity evolution in brown algae virus interactionsLiping Wang Max Planck Institute for Biology T bingen GermanySession 2 The genotype phenotype mapSession chair Gilles Fischer Sorbonne University France11 40 12 10Evolution of the genotype phenotype map across an entire subphylum of yeastsAntonis Rokas Vanderbilt University USA12 10 12 30Robust genetic codes enhance protein evolvability Hana Rozhonov Charles University Czech Republic12 30 13 30Lunch and meet the speakers13 30 14 10Flash talks by poster presenters odd numbers 43 Fabrizio Angaroni 63 Anna Czerwinski 83 Chlo Haberkorn 93 Tera Levin 99 Paul Mathias Jansen 109 Lea Kloss 117 Ming Liu 119 Tomoya Maeda 123 Nora Martin 133 Ambre Noly 145 Zsuzsa Sarkadi 149 Andreas Sichert 153 Junya Sunagawa 161 Isabella Tomanek 163 Nikolaos Vakirlis 169 Andriy Volkov14 10 16 00Poster session 1 odd numbers Poster listing16 00 17 00Meet the editorsSerena Bradde PRX Life USAVera Domingues Nature Ecology Evolution UKAndrea Du Toit Nature Reviews Microbiology UKFrancois Mayer Nature Microbiology GermanyStephanie McClelland Springer Nature GermanyYehu Moran EMBO Press GermanyRoland Roberts PLoS Biology UK17 00 17 30Ecological dynamics of bacterial cell collectivesJulia Schwartzman University of Southern California USANot available on demand17 30 18 00Highly parallel evolution in a recombination driven molecular arms raceGeorg Hochberg Max Planck Institute for Terrestrial Microbiology Germany18 00 18 30Interpreting the evolution of SARS CoV 2Jesse Bloom Howard Hughes Medical Institute Fred Hutchinson Cancer Center virtual speaker 18 30 18 50From infection to protection how prophages contribute to antiviral defence in Pseudomonas aeruginosa Anna Olina University of Exeter United Kingdom18 50 19 10Quantitative analysis of repeatability and contingency in antibiotic resistance evolution Gabriela Petrungaro University of Cologne Germany19 10 20 40Dinner in EMBL Canteen20 40 22 00After dinner drinks in ATC Foyer Day 3 Thursday 10 October 2024 Time Europe Berlin SpeakerSession 3 Coevolution across trophic levelsSession chair Jordi van Gestel EMBL Heidelberg Germany09 00 09 30Mobile genetic elements shape the honey bee microbial communityIrene Newton Indiana University USA09 30 09 50Recurrent hybridization to introgression cycles in a yeast populationEugenio Mancera Centro de Investigaci n y de Estudios Avanzados del Instituto Politecnico Nacional MexicoNot available on demand09 50 10 10Sedentary chromosomal integrons as biobanks of bacterial anti phage defence systems Eloi Littner Institut Pasteur France10 10 10 30Retracing the horizontal transfer of a novel innate immune factor in Drosophila Rebecca Tarnopol University of California Berkeley USA10 30 11 00Coffee break and meet the speakers11 00 11 30Evolution of anti viral immunity across domains of lifeAude Bernheim Institut Pasteur France11 30 12 00Evolution of C elegans microbe interactionsHinrich Schulenburg Kiel University Germany12 00 12 20Experimental evolution of evolvability Michael Barnett Max Planck Institute for Evolutionary Biology Germany12 20 13 30Lunch and meet the speakers13 30 14 10Flash talks by poster presenters even numbers 42 Danielle Adekunle 48 Stefan Bassler 70 Alice Dufour 72 Sarah Frail 90 Mathieu H nault 102 Jean Baptiste Boule 106 Dan Kehila 116 Jun Liu 132 Mariana Natalino 134 Francisco Cubillos 142 Lucas Santana Souza 148 Ton Sharoni 150 Luca Soldini 152 Aleksandar Stanojkovic 158 Nicol Tellini 160 AmirAli Toghani 162 Vjaceslav Tretjacenko 166 Petra Vande Zande14 10 16 00Poster session 2 even numbers Poster listingFree eveningOptional Castle tour limited space available sign up on site Day 4 Friday 11 October 2024 Time Europe Berlin SpeakerSession 4 Assembly and evolution of communitiesSession chair Sara Mitri University of Lausanne Switzerland09 00 09 30Understanding and predicting microbiome dynamics Kat Coyte University of Manchester UK09 30 09 50Divergence in gene expression plasticity is driven by a blend of trans regulatory mechanismsAnna Redhuis University of Michigan USA09 50 10 10The link between amoeba predation virulence and multicellularity in yeast Helen Murphy William Mary USA10 10 10 50Coffee break and meet the speakers10 50 11 20Candida biofilms importance regulation and evolutionClarissa Nobile University of California Merced USA11 20 11 50Evolutionary genetics of opportunistic bacteria growing on surfaces or in hostsVaughn Cooper University of Pittsburgh USA11 50 12 10Relationship between bacterial interspecies interactions and carbon source diversity Hiroki Ono The University of Tokyo Japan12 10 12 30How does the environment shape bacterial interactions Josephine Solowiej Wedderburn Ume University Sweden12 30 14 00Lunch and meet the speakers14 00 14 30Global ecological interactions enable prediction of community level functionsJuan D az Colunga CSIC University of Salamanca Spain SpainSession 5 Innovative integrative approaches for ecology and evolutionSession chair Kimberly Kline University of Geneva Switzerland14 30 15 00The role of metabolism in shaping enzyme structures over 400 Million years of evolutionMarkus Ralser Charit University Medicine Germany15 00 15 20Genome wide sweeps create fundamental ecological units in the human gut microbiome Xiaoqian Yu University of Vienna Austria15 20 16 00Coffee break and meet the speakers16 00 16 20Understanding the functional range of antiphage systems in Pseudomonas aeruginosaAleksei Agapov University of Exeter UK16 20 16 50What chemicals do to our bugs Kiran Patil University of Cambridge UKNot available on demand16 50 17 10Genetic and ecological determinants of bacterial pathogen success during plant infection Julien Luneau University of Lausanne Switzerland17 10 17 40Coffee break and meet the speakers17 40 18 10Mapping the human body one cell at a timeSarah Teichmann Cambridge Stem Cell Institute UK virtual speaker 18 10 18 30From molecules to communities predicting the emergent properties of spatially structured microbial systems Simon van Vliet University Basel Switzerland18 30 18 50The role of mutational buffering genes in shaping the phenotypic effects of de novo mutations Mohammed Tawfeeq VIB KU Leuven Center for Microbiology Belgium18 50 19 00Closing remarks and poster prizes19 00 20 30Dinner in EMBL Canteen20 30 23 30Party in the ATC Foyer with band Practical information Registration fees and abstract submission On site registration fees include admission conference materials meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Virtual registration fees include access to all of the talks livestreamed and on demand and facility to submit questions On site Academia 550On site PhD Student 350On site Industry 750On site Journal Editors 300Virtual Academia 200Virtual PhD Student 150Virtual Industry 275 Editors from scientific journals are allowed to attend at a reduced rate but asked to contribute to the conference in return by taking part in meet the editors sessions or other planned activities within the programme A letter to support your visa application will be issued on request once payment of the registration fee is confirmed We recommend that you book your visa appointment as soon as possible to avoid any delay with your visa application Accredited journalists may be eligible to register for complimentary press registration Registrants may be required to provide accreditation or equivalent proof of press membership after registration Please contact Aline Schnieder for more information Please note that we do not offer complimentary registrations for editors of scientific journals Confirmation and payment Registration will be on a first come first served basis Your place can only be confirmed after payment of the registration fee If you are added to our waiting list please consider taking advantage of our offerings to participate virtually On site participants Types of payments accepted are international bank transfers and credit card payments Virtual participants We are only able to accept card payments In exceptional cases we can accept bank transfers Please contact events embl de for details Abstract submission Only participants registering to attend the on site event are eligible to submit an abstract Abstracts will not be accepted from virtual participants After registration you can submit your abstract via a separate link that will be provided in the email confirmation Alternatively you can access the link on the confirmation page directly after registering The same login credentials are used for both processes Please note Abstract body The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised Title The title should not exceed 20 words Only the first word of the title should start with a capital letter and the rest should be lowercase Authors and affiliations Please fill in the author s details as requested in the online form The compulsory fields are First Name Last Name Organisation Name Affiliation or Company Country and Email Kindly mark only one author in the role of First Author and please don t forget to indicate who will be the Presenter Please enter your co authors correctly via the system by adding accounts together with their organisation institute Do not copy paste them into the body of the abstract text as they will not be indexed in the abstract book Presentation types When submitting your abstract you can apply for an oral or poster presentation A selection process will take place with the results announced 2 3 weeks after the abstract submission deadline For detailed instructions on how to submit a conference abstract follow the instructions provided in this video Please check our FAQs pages for further information on how to submit an abstract Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of registration fee waivers travel grants and childcare grants Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course or conference Travel grant The travel grant will cover the cost of travel to an on site event airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from within Europe up to 1000 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from outside Europe up to 500 for any participant travelling to an EMBO Workshop up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Workshop up to 700 for any participant working in Croatia Czech Republic Estonia Greece Hungary Italy Lithuania Luxembourg Poland Slovenia and Turkey travelling to an EMBO Workshop Registration fees are only covered for EMBO Workshops The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant There is the possibility to apply for a childcare grant to offset child care costs incurred by participants speakers and organisers when attending a conference Eligible costs include but are not limited to fees for a baby sitter or child care facility and travel costs for a caregiver Please note that priority will be given to early stage researchers In order to apply for this grant you must be registered by the abstract submission deadline There is a limited amount of funding available for the childcare grants and funds will be distributed amongst eligible applicants Application On site participants You may apply for financial assistance when submitting your abstract In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Virtual participants If you are attending virtually you can apply for financial assistance in the submission portal by the abstract deadline Read the instructions on how to apply for financial assistance Only submissions for financial assistance will be accepted Presentation abstracts cannot be submitted here and will be declined In your application you will be asked to summarise your current work answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Selection The scientific organisers will select the recipients of registration fee waivers and travel grants during the motivation letter or abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection for registration fee waivers and travel grants is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Childcare grants will be allocated in the same timeframe 6 8 weeks before the event start date Please note that priority will be given to early stage researchers Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details View our list of external funding opportunities and information on attending a conference as an event reporter For further information about financial assistance please refer to the FAQ page Accommodation and travel Accommodation is not included in the conference registration fee The hotels below have rooms on hold for participants until 10 September 2024 in some cases at special rates Please email the hotel directly quoting the booking code EAE24 01 to confirm the exact price of the room Hotel AnlageHotel ibis HeidelbergPremier Inn Heidelberg CityHotel Bayrischer Hof ISG Hotel Staycity Aparthotel HeidelbergB B HotelHilton Heidelberg Travel information For travel information please see here If you are travelling to the conference within Germany then you are eligible for the Deutsche Bahn Event Ticket called the Veranstaltungsticket in German This will result in a lower ticket price if your travel distance to Heidelberg is more than 100 km You need to provide proof of your event attendance when purchasing the ticket For more information in English see here or in German see here You can book your ticket here Conference shuttle buses Conference shuttle buses are free of charge for participants and depart from designated bus stops near the hotels to EMBL and back mornings and evenings Please find the conference shuttle bus schedule here The bus stops for this conference are Staycity Aparthotel Speyerer Str 7 Kurf rsten Anlage Opposite Main Train Station Premier Inn Kurf rsten Anlage 23 Leonardo Hotel Heidelberg City Center Bergheimer Str 63 Neckarm nzplatz Heidelberg Tourist Information Peterskirche Bus stop Hans B ckler Stra e Bus stop Rohrbacher Str 22 ISG Hotel Im Eichwald 19 View Conference shuttle bus stops and hotels in a larger map Please note that not every bus stop will be used for every event Further details Address EMBL Meyerhofstra e 1 69117 Heidelberg Germany For more information about accommodation and travel please refer to the FAQ page On site information Catering All meals and coffee breaks are included in the registration fee Our catering staff will prepare a wide variety of vegetarian meals meat and fish dishes soups pasta fresh fruit and vegetables as well as a variety of desserts Please wear your badge at all times when serving yourself No food or drinks are allowed in the auditorium Charging lockers There are lockers available next to the stairs leading down into the Auditorium You will find some of those equipped with sockets to charge your smartphone tablet etc Electricity and charging station In most places the electricity is 220 volts AC 50 cycles An adaptor and a plug that fits the German socket may be needed for your appliances laptop i e American Japanese etc A USB charging station for electronic devices is available at the registration desk EMBL merchandise If you are interested in purchasing EMBL merchandise products presented in the glass display in the registration area please email the EMBL shop to place an order or get in contact with your Course Organiser Kindly note the EMBL shop is only open upon request and all purchases must be made in cash Euros only Health and safety notes Please read EMBL s COVID 19 safety policy for on site events Do not smoke in any EMBL building Eating and drinking is prohibited in the Auditorium and all laboratories Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required The first aid room is located next to the ATC Registration Desk room 10 205 Dial the Emergency number 222 from any EMBL internal phone only Where is the accident What happened How many injured Emergency number 06221 387 7821 from mobile phones Please report all accidents to the conference officer at the registration desk In case of fire Press the nearest fire alarm button or the Emergency number 222 from any internal phone A loud fire alarm will go off if an evacuation is required On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting points Do not use the lifts Beyond first aid Please remember to bring your own medication if needed to the conference Note that the next pharmacy is a 4 minute drive from the EMBL but for many medications you will be required to see a doctor to get a prescription Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg In any case the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary Internet Wi Fi is available on campus using the EMBL Events network and the event specific password which will be provided on site The eduroam network secure worldwide roaming access service developed for the international research and education community is also available Lost and found Lost and Found items are kept at the registration desk until the end of the conference Luggage There are lockers available on site to store your luggage which require a 2 EURO coin to operate There is another luggage room on level E0 which is free to use but remains unlocked during the conference Nursing room There is a nursing room available in the ATC Rooftop Lounge on level A29 Photography During the conference an EMBL Photographer may be taking photos If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Printing We can help to print your boarding pass train ticket Please send it to events embl de and collect your print outs at the registration desk Room for prayer yoga and meditation There is a room for prayer meditation and yoga located on level E0 behind the Auditorium Please be respectful of others using the room Sightseeing A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing Travel to and from the venue During the event we provide conference shuttle buses to and from EMBL In addition there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time Information on the conference shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page Useful German expressions HelloHalloGoodbyeAuf Wiedersehen formal Tsch ss informal Good morningGuten MorgenGood afternoonGuten TagGood eveningGuten AbendGood nightGute NachtI m sorryEs tut mir leidExcuse me Entschuldigen SieHow are you Wie gehts I m fine thanks And you Mir geht es gut danke Und Dir Ihnen What is your nameWie hei en Sie formal Wie hei t Du informal My name isIch hei e Do you speak EnglishSprechen Sie Englisch I don t understandIch verstehe nichtPlease speak more slowlyK nnen Sie bitte langsamer sprechenThank youDankesch nWhere is the toilet Wo ist die Toilette Please call me a taxiBitte rufen Sie mir ein TaxiHow do I get to Wie komme ich zum zur A beer two beers pleaseEin Bier zwei Bier bitteA glass of red white wine pleaseEin Glas Rot Weisswein bitteThe menu pleaseDie Speisekarte bitteIs there a local speciality Gibt es eine Spezialit t aus dieser Gegend I m vegetarianIch bin Vegetarier VegetarierinIt was deliciousEs war hervorragendThe bill pleaseDie Rechnung bitteI have a headacheIch habe KopfschmerzenI have a sore throatIch habe HalsschmerzenMy stomach hurtsIch habe MagenschmerzenI m allergic toIch bin allergisch gegenI need a doctor who speaks EnglishIch brauche einen Arzt der Englisch spricht Virtual participation What s included Access to all the livestreamed talks Video library of the recorded talks during the event and for two weeks afterwards Please note at the request of individual speakers some talks are not recorded Facility to submit questions Talks will only be recorded upon speaker s consent Please note that only on site participants are able to submit abstracts and participate in the poster sessions Event platform We are using an event platform for this conference More information about the platform will be shared ahead of the conference Guidelines Do not broadcast the conference to unregistered participants You are encouraged to tweet and post about the event Tweet unless the speaker specifically says otherwise but be mindful of unpublished data Please do not capture transmit or redistribute data presented at the meeting Additional information can be found in our Code of Conduct Health and well being It is important to stay healthy and move around especially when you are attending an event virtually We have put together a few coffee break stretches and yoga videos in the conference platform for you to enjoy during the event How to ask questions Please use the Q A function in the event platform If you have any other questions you can go to the Help Desk in the event platform Click on more on the top menu and click Help Desk Time zone The programme is planned based on the Europe Berlin time zone unless otherwise stated Please take your time zone into consideration when planning your attendance Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for participants page COVID 19 related questions COVID 19 information for on site events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Media partners ChemBioChem a Wiley Journal EMBO Reports an EMBO Press journal International Union of Biochemistry and Molecular Biology Journal of Molecular Biology an Elsevier journal Medinformatics a Bon View Publishing journal Open Biology a Royal Society journal PLOS Biology a PLOS journal Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information on sponsoring possibilities If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de Media Kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9 Leaderboard 728 90...

Gilles Fischer, Jordi van Gestel, Kimberley Kline, Sara Mitri, Antonis Rokas

EMBO Workshop

EMBL Heidelberg, Virtual

2 October 2024

Building a spatial transcriptomics platform

Edit

October 02, 2024 15:302024WebinarVirtual

Description The Light Imaging Facility LIF at EMBL Rome offers training and support to users for experimental design tissue sample processing imaging data acquisition and image analysis Importantly the LIF is also involved in technology development ensuring access to innovative sample and imaging techniques such as spatial transcriptomics and expansion microscopy This webinar will demonstrate how we built a service platform for spatial transcriptomics using our in house developed methods...

Virtual

1 October - 5 October 2024

Computational Biology Training in Hematology 2024, Module 2

Edit

October 01, 2024 00:002024CourseEMBL Heidelberg

Description Computational Biology Training in Hematology CBTH provides early career researchers aiming to specialize in computational and quantitative biology aspects of hematology with a unique year long training and mentoring experience by top tier faculty CBTH is a joint effort of the European Hematology Association EHA and the European Molecular Biology Laboratory European Bioinformatics Institute EMBL EBI that aims to support the development of quantitative skills for hematology researchers through training and mentoring in computational biology...

Barbara Etzi

EMBL Heidelberg

30 September - 3 October 2024

Defining and defeating metastasis

Edit

September 30, 2024 00:002024ConferenceEMBL Heidelberg, Virtual

Description OverviewSpeakersProgrammePractical informationPre conference workshopSponsorsAboutMedia kit Overview Late registration is still available Please reach out to events embl org to request it This conference will take place at EMBL Heidelberg with the option to attend virtually Symposium overview In its second edition this symposium will cover emerging key concepts of latent metastasis and dissemination of tumour cells including evolution and genetic diversity of metastasis circulating tumour cells stemness dormancy and stromal reprogramming transcriptional and epigenetic control motility and invasive signalling metastatic heterogeneity EMT and plasticity immune evasion and metabolic adaptations The meeting will provide a unique interdisciplinary exchange on current approaches and future collaborations on metastasis and its therapeutic challenges Metastasis research is a nexus for several of the most exciting areas and technical developments of current cancer biology and translational molecular medicine High resolution intravital imaging single cell sequencing and integrated genomics approaches innovative tissue modelling and co culture systems for disease screening and patient stratification all have enormous implications for our basic understanding of the mechanisms of this deadly disease and hold great promises for progress in its successful treatment This cutting edge meeting is aimed at a broad spectrum of life scientists and clinicians working in cancer immunology cell and molecular biology Session topics Metastasis initiating cells circulating tumour cells Motility and invasion Transcriptional and epigenetic control of metastasis Metastasis heterogeneity EMT and plasticity Metastasis signalling and latency Metastasis imaging tumour microenvironment and immune evasion What past participants say about the Symposium The Defining and Defeating Metastasis Symposium was probably the best conference I have attended during my PhD Engaging speakers new science and plenty of opportunity to network and socialise all a stone s throw from the centre of beautiful Heidelberg Hoping for a repeat event in the future Emma Colliver Francis Crick Institute UK As a PhD student in breast cancer research the symposium in Defining and defeating metastasis was amazing The speakers were excellent and I left the conference with a lot of learning from established and new researchers The EMBL Heidelberg venue was quiet and provided a good backdrop to discuss current research in metastasis Catering was great with many vegan vegetarian options as well The conference provided a lot of opportunities to network with other fellow students but also with established researchers Jomar Gustave Roussy Universite Paris Saclay France Defining and Defeating Metastasis was the most engaging and stimulating conference I ever attended EMBL location is amazing and the conference was perfectly organised Mila Gugnoni Laboratory of Translational Research AUSL IRCCS Reggio Emilia Italy The level of the science presented was great did a marvellous work covering broad and key aspects of metastasis development Beatriz P rez Garvan MRI Australia virtual participant Speakers Keynote speakers Mikala Egeblad Johns Hopkins University USA Sean Morrison Children s Research Institute USA Speakers Julio Aguirre Ghiso Albert Einstein College of Medicine USA Salvador Aznar Benitah Institute for Research in Biomedicine Spain C dric Blanpain Universit Libre de Bruxelles Belgium Kevin Cheung Fred Hutchinson Cancer Center USA Caroline Dive University of Manchester UK Michaela Frye DKFZ Germany Karuna Ganesh Memorial Sloan Kettering Cancer Center USA Trevor Graham The Institute of Cancer Research UK Rene Jackstadt HI STEM and DKFZ Germany Ilaria Malanchi The Francis Crick Institute UK Belinda Parker Peter MacCallum Cancer Centre Australia Victoria Sanz Moreno The Institute of Cancer Research UK Marisol Soengas Spanish National Cancer Research Center CNIO Spain Samra Turajlic The Francis Crick Institute UK Jacco van Rheenen The Netherlands Cancer Institute The Netherlands Scientific organisers Eduard Batlle Institute for Research in Biomedicine Spain Johanna Joyce University of Lausanne Switzerland Daniel Klimmeck The EMBO Journal Germany Joan Massagu Memorial Sloan Kettering Cancer Center USA Samra Turajlic The Francis Crick Institute UK Conference organiser Inna B sselmann EMBL Heidelberg Germany Programme Are you on social media Post using EESMetastasis and don t forget to tag EMBLEvents Please note that the programme is subject to change Some speakers may need to join virtually to give their talk For registered participants recorded talks will be accessible on demand for 2 weeks after the end of the event unless indicated otherwise Day 1 Monday 30 September TimeSpeaker11 45 13 30Registration and light refreshments12 15 13 15Pre conference workshop with GemPharmatec13 30 13 45Opening remarks by Joan Massagu 13 45 14 30 Keynote lecture Human osteosarcoma metastasis is limited by oxidative stressSean Morrison UT Southwestern Medical Center USA13 45 17 45Session 1 Chair Marisol Soengas National Cancer Research Center Spain14 30 15 00Age related host mosaicism as a driver of dormant cancer cell awakening in the lungJulio Aguirre Ghiso Albert Einstein College of Medicine USANot available on demand15 00 15 15Zeb1 mediated control of the PUFA MUFA ratio in EMT associated ferroptosis sensitivityNino Bindel FAU Erlangen N rnberg Germany15 15 15 30Aiding and aBETting metastasis Epigenetic driven awakening in ER breast cancerHazel Quinn ISREC EPFL Switzerlandvirtual speaker15 30 16 00Coffee break and meet the speakers16 00 16 30Deciphering and targeting of fetal like stem cells in metastatic colorectal cancerRene Jackstadt German Cancer Research Center DKFZ GermanyNot available on demand16 30 16 45Homopolymer switches mediate adaptive mutability in mismatch repair deficient colorectal cancerSuzanne van der Horst UMC Utrecht The Netherlands16 45 17 00Dual metastasis and tumor inhibitory efficacy of a first in class metastasis initiating cell targeted therapeutic antibodyKelvin Kunchih Tsai Taipei Medical University Taiwan17 00 17 30Impact of emergency granulopoiesis on metastasisIlaria Malanchi The Francis Crick Institute UK17 30 19 00Dinner in EMBL Canteen19 00 21 00Science Pub Quiz after dinner drinksEMBL Canteen Day 2 Tuesday 1 October TimeSpeaker09 00 12 00 Session 2 Chair Sean Morrison UT Southwestern Medical Center USA09 00 09 30Systemic rewiring of dendritic cells in melanoma progression implications for immune checkpoint blockadeMarisol Soengas National Cancer Research Center Spain09 30 09 45Gene expression adaptation of metastasis to their host tissueLuise Nagel University of Cologne Germany09 45 10 00Antagonism between tumors and lymphocytes drives coevolutionary processes throughout metastasisCort Breuer Stanford University United States of America10 00 10 15Intestinal bacteria are trapped alongside the nuclei of colorectal cancer cells survival in a foreign yet safe environment Reinhild Feuerstein University Medical Center Freiburg Germany10 15 10 45Coffee break and meet the speakers10 45 11 00Single molecule Liquid Biopsy Systems for Multiplexed Detection of Epigenetic Modifications and Oncoproteins for Cancer DiagnosticsNoa Furth Weizmann Institute of Science Israel11 00 11 15Role of MYC in liver metastatic pancreatic ductal adenocarcinoma and therapeutic resistanceRosalie Sears Oregon Health and Science University United States of America 11 15 11 45Bringing bone metastases out of hiding for therapeutic targetingBelinda Parker Peter MacCallum Cancer Centre AustraliaNot available on demand11 45 12 00Flash talks session 1 3 min per talk Poster numbers 60 70 72 83 8512 00 13 30Lunch and meet the editors 13 00 13 30Imaging Centre ToursSeparate Registration required please await further information before eventGuided by Timo Zimmermann and Stephanie Alexander13 30 15 00Poster Session 1 odd numbers 15 00 15 30Coffee break and meet the speakers15 30 17 30Session 3 Chair Ilaria Malanchi The Francis Crick Institute UK15 30 16 00Dissecting plasticity during colorectal cancer metastasisKaruna Ganesh Memorial Sloan Kettering Cancer Center USANot available on demand16 00 16 15A senescence like state of tumor cells contributes to tumor aggressiveness and makes them vulnerable to senolysisMathieu Boissan Sorbonne University FranceNot available on demand16 15 16 30Loss of STAG2 leads to EWS FLI1 dependent and independent rewiring of enhancer promoter contacts and contributes to aggressive Ewing sarcomaAna Cuadrado Spanish National Cancer Research Centre Spain16 30 16 45Marking out cancer stem cells that drive gastric tumourigenesis in mice and humansGrace Lim Institute of Molecular and Cell Biology A STAR Singapore16 45 17 15Mechanisms regulating EMT statesC dric Blanpain Universit libre de Bruxelles Belgium17 15 Free evening18 00 19 00Optional guided tour Old town Heidelberg Day 3 Wednesday 2 October TimeSpeaker09 00 12 00Session 4 Chair Mikala Egeblad Johns Hopkins University School of Medicine USA09 00 09 30Systemic impact of metastasis over host metabolismSalvador Benitah Aznar Institute for Research in Biomedicine Barcelona SpainVirtual talk09 30 09 35Beug foundation awardees of 2023 Chair Martin Jechlinger EMBL Heidelberg Germany09 35 10 15Beug metastasis foundation awardees 2023 Ilaria Elia Katholieke Universiteit BelgiumColinda Scheele Katholieke Universiteit BelgiumToni Celi Terrassa Research Institute Hospital del Mar IMIM SpainIoanna Keklikoglou University of Crete Greece10 15 10 45 Coffee break and meet the speakers10 45 11 00Utilising gene editing technology to uncover novel immunotherapies for targeting bone metastases in breast cancerThomas Chadwick Peter MacCallum Cancer Centre Australia11 00 11 15Role of Epsin 3 in breast cancer tumorigenesis and metastasisAmir Fardin European Institute of Oncology Italy11 15 11 45Cell and tissue state transitions regulating collective metastasisKevin Cheung Fred Hutchinson Cancer Center USANot available on demand11 45 12 00Flash talks session 2 3 min per talk Poster numbers 82 94 96 98 10212 00 13 30Group photo Lunch 12 30 13 30Career discussion session in Courtyard room Charting Your Path Insights into Successful Careers in Fundamental and Translational Cancer Research Presenters Johanna Joyce University of Lausanne Switzerland Samra Turajlic The Francis Crick Institute UK13 30 16 15 Session 5 Chair C dric Blanpain Universit libre de Bruxelles Belgium13 30 14 00Filming the fate of cells carrying mutations in cancer driver genesJacco van Rheenen The Netherlands Cancer Institute The NetherlandsNot available on demand14 00 14 15Dynamic analysis of individual cells from metastasizing populations with holographic incoherent light source quantitative phase imagingDaniel Zicha CEITEC VUT Brno Czech Republic14 15 14 30Breast cancer remodels the bone marrow lymphoid microenvironment to favor bone metastasisAna Teijeiro National Institute of Allergy and Infectious Diseases NIAID USA14 30 15 00The role of genome instability and immune evasion in metastasisSamra Turajlic The Francis Crick Institute UK15 00 15 30Coffee break and meet the speakers15 30 15 45Two distinct epithelial to mesenchymal transition programmes control invasion and inflammation in segregated tumour cell populationsKhalil Kass Youssef Instituto de Neurociencias de Alicante CSIC UMH Spain15 45 16 00Understanding the molecular mechanism behind tandem motifs induced CtBP polymerization in pre clinical and clinical modelsNishit Goradia University Medical Center Hamburg Eppendorf Germany16 00 16 15Sybodies to inhibit the metastasis promoting activity of Cofilin 1 by replacing the protein from F actinSabine Windhorst University Medical Center Hamburg Eppendorf Germany16 15 16 45Small Cell Lung Cancer MetastasisCaroline Dive University of Manchester UKNot available on demand16 45 18 15Poster Session 2 even numbers 18 15 20 15Conference dinner in EMBL Canteen20 15 23 45 Party with DJ Jenz in ATC Rooftop Lounge Day 4 Thursday 3 October Time Speaker09 00 12 30 Session 6Chair Jacco van Rheenen Netherlands Cancer Institute The Netherlands09 00 09 30 Metastatic evolution of colorectal cancerTrevor Graham Institute of Cancer Research UK09 30 09 45Tumor microenvironment induced FOXM1 regulates ovarian cancer stemnessChiara Battistini European Institute of Oncology IRCCS Italy09 45 10 00Emerin mis localization during chromatin bridge resolution can drive prostate cancer cell invasiveness in collagen rich microenvironmentPaulina Nastaly Medical University of Gdansk Poland 10 00 10 15Mitochondrial J protein JC15 effected metabolic rewiring induces aggressive tumour phenotypes in breast cancer cellsPriyadarshika Pradhan Banaras Hindu University Indiavirtual speaker10 15 10 45Coffee break and meet the speakers10 45 11 15Targeting RNA modifications in cancerMichaela Frye DKFZ Germany11 15 11 45Biomechanical hallmarks and vulnerabilities of metastatic cancer cellsVictoria Sanz Moreno The Institute of Cancer Research ICR UK11 45 12 30Keynote lecture NETworking with cancer The bidirectional interplay between cancer and neutrophil extracellular trapsMikala Egeblad Johns Hopkins University School of Medicine USA12 30 13 00Closing remarks and Poster prizes by the Scientific Organizers13 00 13 30Packed lunch and departure13 30Bus to airport tickets available at registration desk Conference shuttle to the Main station and hotels Practical information Registration fees and abstract submission On site registration fees include admission conference materials meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Virtual registration fees include access to all of the talks livestreamed and on demand and facility to submit questions On site Academia 725On site PhD Student 625On site Industry 925Virtual Academia 225Virtual PhD Student 175Virtual Industry 275 Editors from scientific journals are allowed to attend at a reduced rate but asked to contribute to the conference in return by taking part in meet the editors sessions or other planned activities within the programme A letter to support your visa application will be issued on request once payment of the registration fee is confirmed We recommend that you book your visa appointment as soon as possible to avoid any delay with your visa application Accredited journalists may be eligible to register for complimentary press registration Registrants may be required to provide accreditation or equivalent proof of press membership after registration Please contact Inna Boesselmann for more information Please note that we do not offer complimentary registrations for editors of scientific journals Confirmation and payment Registration will be on a first come first served basis Your place can only be confirmed after payment of the registration fee If you are added to our waiting list please consider taking advantage of our offerings to participate virtually On site participants Types of payments accepted are international bank transfers and credit card payments Virtual participants We are only able to accept card payments In exceptional cases we can accept bank transfers Please contact events embl de for details Abstract submission Only participants registering to attend the on site event are eligible to submit an abstract Abstracts will not be accepted from virtual participants After registration you can submit your abstract via a separate link that will be provided in the email confirmation Alternatively you can access the link on the confirmation page directly after registering The same login credentials are used for both processes Please note Abstract body The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised Title The title should not exceed 20 words Only the first word of the title should start with a capital letter and the rest should be lowercase Authors and affiliations Please fill in the author s details as requested in the online form The compulsory fields are First Name Last Name Organisation Name Affiliation or Company Country and Email Kindly mark only one author in the role of First Author and please don t forget to indicate who will be the Presenter Please enter your co authors correctly via the system by adding accounts together with their organisation institute Do not copy paste them into the body of the abstract text as they will not be indexed in the abstract book Presentation types When submitting your abstract you can apply for an oral or poster presentation A selection process will take place with the results announced 2 3 weeks after the abstract submission deadline For detailed instructions on how to submit a conference abstract follow the instructions provided in this video Please check our FAQs pages for further information on how to submit an abstract Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of both registration fee waivers and travel grants These are available for on site participants at EMBL Conferences and EMBO EMBL Symposia and for on site and virtual participants at EMBO Workshops We are currently working on securing funding for all virtual participants and ask that you please apply for financial assistance for both on site and virtual participation Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course or conference Travel grant The travel grant will cover the cost of travel to an on site event airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from within Europe up to 1000 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from outside Europe up to 500 for any participant travelling to an EMBO Workshop up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Workshop up to 700 for any participant working in Croatia Czech Republic Estonia Greece Hungary Italy Lithuania Luxembourg Poland Slovenia and Turkey travelling to an EMBO Workshop Registration fees are only covered for EMBO Workshops The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Application On site participants You may apply for financial assistance when submitting your abstract In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Virtual participants If you are attending virtually you can apply for financial assistance in the submission portal by the abstract deadline Read the instructions on how to apply for financial assistance Only submissions for financial assistance will be accepted Presentation abstracts cannot be submitted here and will be declined In your application you will be asked to summarise your current work answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Selection The scientific organisers will select the recipients of all financial assistance during the abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details View our list of external funding opportunities and information on attending a conference as an event reporter For further information about financial assistance please refer to the FAQ page Accommodation and travel Accommodation is not included in the conference registration fee As further changes in our events are possible you should book flights trains and hotels with flexible options and favourable cancellation conditions The hotels below have rooms on hold for participants until 2 September 2024 in some cases at special rates Please email the hotel directly quoting the booking code EES24 10 to confirm the exact price of the room B B HotelStaycity Aparthotel HeidelbergHotel ibis HeidelbergSteffi s Hostel HeidelbergISG Hotel Hilton HeidelbergMeininger HeidelbergPremier Inn Heidelberg City Travel information For travel information please see here If you are travelling to the conference within Germany then you are eligible for the Deutsche Bahn Event Ticket called the Veranstaltungsticket in German This will result in a lower ticket price if your travel distance to Heidelberg is more than 100 km You need to provide proof of your event attendance when purchasing the ticket For more information in English see here or in German see here You can book your ticket here Conference shuttle buses Conference shuttle buses are free of charge for participants and depart from designated bus stops near the hotels to EMBL and back mornings and evenings Please find the conference shuttle bus schedule here The bus stops for this conference are Hotel Staycity Speyerer Str 7 Kurf rsten Anlage Opposite Main Train Station Hotel Premier Inn Kurf rsten Anlage 23 Leonardo Hotel Bergheimer Str Neckarmuenzplatz Peterskirche Hilton Hotel Kurf rsten Anlage 1 ISG Hotel View Conference shuttle bus stops and hotels in a larger map Please note that not every bus stop will be used for every event You can find the final bus schedule here Further details Address EMBL Meyerhofstra e 1 69117 Heidelberg Germany For more information about accommodation and travel please refer to the FAQ page On site information Catering All meals and coffee breaks are included in the registration fee Our catering staff will prepare a wide variety of vegetarian meals meat and fish dishes soups pasta fresh fruit and vegetables as well as a variety of desserts Please wear your badge at all times when serving yourself No food or drinks are allowed in the auditorium Charging lockers There are lockers available next to the stairs leading down into the Auditorium You will find some of those equipped with sockets to charge your smartphone tablet etc Electricity and charging station In most places the electricity is 220 volts AC 50 cycles An adaptor and a plug that fits the German socket may be needed for your appliances laptop i e American Japanese etc A USB charging station for electronic devices is available at the registration desk EMBL merchandise If you are interested in purchasing an EMBL souvenir products presented in the glass display in the registration area please ask at the registration desk for more information Health and safety notes Please read EMBL s COVID 19 safety policy for on site events Do not smoke in any EMBL building Eating and drinking is prohibited in the Auditorium and all laboratories Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required The first aid room is located next to the ATC Registration Desk room 10 205 Dial the Emergency number 222 from any EMBL internal phone only Where is the accident What happened How many injured Emergency number 06221 387 7821 from mobile phones Please report all accidents to the conference officer at the registration desk In case of fire Press the nearest fire alarm button or the Emergency number 222 from any internal phone A loud fire alarm will go off if an evacuation is required On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting points Do not use the lifts Beyond first aid Please remember to bring your own medication if needed to the conference Note that the next pharmacy is a 4 minute drive from the EMBL but for many medications you will be required to see a doctor to get a prescription Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg In any case the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary Internet Wi Fi is available everywhere on the premises using the EMBL Events network and the event specific password which will be provided on site The eduroam network secure world wide roaming access service developed for the international research and education community is also available Lost and found Lost and Found are kept at the registration desk until the end of the conference Luggage There are lockers available on site to store your luggage which require a 2 EURO coin to operate There is another luggage room on level E0 which is free to use but remains unlocked during the conference Nursing room There is a nursing room available in the ATC Rooftop Lounge on level A29 Photography During the conference an EMBL Photographer may be taking photographs If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Printing We can help printing your boarding passes train ticket Please send it to events embl de and collect your print outs at the registration desk Room for prayer yoga and meditation There is a room for prayer mediation and yoga located on level E0 behind the Auditorium Please be respectful of other participants using the room Sightseeing A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing Travel to and from the venue During the event we provide conference shuttle buses to and from EMBL In addition there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time Information on the conference shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page Useful German expressions HelloHalloGoodbyeAuf WiedersehenGood morningGuten MorgenGood afternoonGuten TagGood eveningGuten AbendGood nightGute NachtI m sorryTut mir leidExcuse me Entschuldigen SieHow are you Wie gehts I m fine thanks And you Mir geht es gut danke und dir Ihnen What is your nameWie heisst du Wie heissen Sie My name isIch heisseDo you speak EnglishSprechen Sie Englisch I don t understandIch verstehe nichtPlease speak more slowlyK nnen Sie bitte langsamer sprechenThank youDankesch nWhere is the toilet Wo ist die Toilette Please call me a taxiBitte rufen Sie mir ein TaxiHow do I get to Wie komme ich zum zur A beer two beers pleaseEin Bier zwei Bier bitteA glass of red white wine pleaseEin Glas Rot Weisswein bitteThe menu pleaseDie Speisekarte bitteIs there a local speciality Gibt es eine Spezialit t aus dieser Gegend I m VegetarianIch bin VegetarierIt was deliciousEs war hervorragendThe bill pleaseDie Rechnung bitteI have a headacheIch habe KopfschmerzenI have a sore throatIch habe HalsschmerzenMy stomach hurtsIch habe MagenschmerzenI m allergic toIch bin allergisch gegenI need a doctor who speaks EnglishGibt es einen Arzt der Englisch spricht Virtual participation What s included Access to all the livestreamed talks Video library of the recorded talks during and after the event Please note at the request of individual speakers some talks are not recorded Facility to submit questions Please note that only on site participants are able to submit abstracts and participate in the poster sessions Event platform We are using an event platform for this conference More information about the platform will be shared ahead of the conference Guidelines Do not broadcast the conference to unregistered participants You are encouraged to tweet and post about the event Tweet unless the speaker specifically says otherwise but be mindful of unpublished data Please do not capture transmit or redistribute data presented at the meeting Additional information can be found in our Code of Conduct Health and well being It is important to stay healthy and move around especially when you are attending an event virtually We have put together a few coffee break stretches and yoga videos in the conference platform for you to enjoy during the event How to ask questions Please use the Q A function in the event platform If you have any other questions you can go to the Help Desk in the event platform Click on more on the top menu and click Help Desk Time zone The programme is planned based on the Europe Berlin time zone unless otherwise stated Please take your time zone into consideration when planning your attendance Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page COVID 19 related questions COVID 19 information for onsite events at EMBL Heidelberg can be found in our COVID 19 FAQs Pre conference workshop For on site participants only This industry webinar will be hosted by our sponsor GemPharmatech Co Ltd before the EMBO EMBL Symposium Defining and defeating metastasis on Monday 30 September 2024 12 15 13 15 Participation in this workshop is free of charge for registered on site conference attendees The workshop room will be announced on site ABSTRACT Genetically modified mouse models for the investigation of disease and protein function mechanisms Hong Yu WANGGemPharmatech Co Ltd Nanjing China The mouse as a model organism plays a crucial role in elucidating disease mechanisms and identifying potential drug targets With the rapid advancement of CRISPR Cas based genome modification techniques in mice we launched the Knock Out All Project KOAP in 2018 to induce mutations in all protein coding genes within the mouse genome using both conventional and conditional floxed methods After five years of effort we have achieved approximately 50 completion of the entire project resulting in the establishment of the largest collection of genetically modified mouse strains As of June 2024 we have generated and prepared for distribution a total of 10 881 knockout KO strains and 9 874 conditional knockout flox cKO strains In order to facilitate engraftment of human cells tissues and organs without rejection by the functional immune system present in mice various immune compromised strains have been developed To this end we directly disrupted Prdkc and Il2rg genes in NOD mice to create an enhanced engraftment model known as NCG with improved acceptance of human immune cells and tissues However the NCG mouse models have limitations when it comes to supporting differentiation of immune cell populations other than T cells such as myeloid cells and NK cells To address this limitation we are developing the next generation of NCG models with specific enhancements such as expression of human cytokines and HLA molecules along with increased engraftment capacity for human cells These new models will be more suitable for studying differentiation of immune cell types and will be made available to academic researchers The enhanced engraftment capability for human immune cells has been validated in our laboratory and relevant data can be downloaded from our website when searching for specific strains Sponsors Silver sponsor Event sponsors Media partners Advanced Biology a Wiley Journal Advanced Genetics a Wiley Journal BioEssays a Wiley Journal ChemBioChem a Wiley Journal Disease Models Mechanisms The Company of Biologists Journal EMBO Molecular Medicine an EMBO Press journal International Union of Biochemistry and Molecular Biology Medinformatics a Bon View Publishing journal Molecular Oncology a FEBS journal Open Biology a Royal Society journal PLOS Biology a PLOS journal Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de About EMBO EMBL Symposia promote scientific communication and collaboration in the European research area They provide scientists with a platform to discuss and exchange ideas on forward looking topics and new developments in the life sciences Topics emphasise upcoming developments and the interdisciplinary nature of related fields Jointly funded and organised by EMBO and EMBL and complementary to their respective courses workshops and conference programmes the symposia promote scientific communication and collaboration All symposia are held in the EMBL Advanced Training Centre ATC in Heidelberg Germany or virtually Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9 Leaderboard 729 90...

Eduard Batlle, Johanna Joyce, Daniel Klimmeck, Joan Massagué, Samra Turajlic

EMBO | EMBL Symposium

EMBL Heidelberg, Virtual

25 September 2024

Developing data infrastructures and analytical systems for spatial omics

Edit

September 25, 2024 15:302024WebinarVirtual

Description Spatially resolved omics technologies are revolutionising our understanding of biological tissues by introducing new ways to characterise tissue architectures and identify cell cell interactions However handling spatial omics datasets remains challenging due to the large heterogeneity of profiling technologies resulting in fragmented file formats and the plethora of arbitrary ways to store analysis results further exacerbates this fragmentation Additionally the data volume often exceeds the memory capacity of standard computing environments These challenges make it difficult to construct scalable interoperable workflows and to share them reproducibly with the scientific community In this webinar we will present a software solution the SpatialData framework that we developed in Python to address these data representation challenges Specifically we will demonstrate how our software infrastructure can be used to Represent data from the most commonly available assays in a unified wayManipulate query and compute statistics on the dataVisualise and annotate the data interactivelyPrepare the data for sharing to maximise interoperability...

Virtual

23 September - 27 September 2024

Metagenomics bioinformatics at MGnify

Edit

September 23, 2024 00:002024CourseVirtual

Meredith Willmott

Virtual

23 September - 27 September 2024

Single-cell RNA-seq analysis with Python

Edit

September 23, 2024 00:002024CourseVirtual

Description This course covers the analysis of single cell RNA seq data using Python and command line tools Participants will be guided through droplet based single cell RNA seq analysis pipelines from raw reads to cell clusters Furthermore you ll learn how to generate common plots for visualisation and analysis of gene expression data including TSNE UMAP and violin plots Please note that participants will not analyse their own data as part of the course There will however be ample opportunity to discuss their research and ideas with other course participants and trainers Virtual courseParticipants will learn via a mix of pre recorded lectures live presentations and trainer Q A sessions Practical experience will be developed through trainer led computational exercises and group activities Live sessions will be delivered using Zoom with additional support and asynchronous communication via Slack Pre recorded material may be provided before the course starts that participants will need to watch read or work through to gain the most out of the actual training event In the week before the course there will be a brief induction session Computational practicals will run on EMBL EBI s virtual training infrastructure meaning participants will not require access to a powerful computer or install complex software on their own machines Participants will need to be available between the hours of 09 00 17 30 BST each day of the course Trainers will be available to assist answer questions and provide further explanations during these times...

Juanita Riveros

Virtual

Edit

September 11, 2024 15:302024WebinarVirtual

Description Spatially resolved transcriptomics enables high throughput gene expression profiling within the spatial context of tissues offering valuable insights into cellular function and tissue organisation By integrating spatial coordinates with gene expression data researchers can identify spatially co localised cell populations and uncover the spatial dynamics of gene expression This webinar will explore the latest technological advances and computational approaches for analysing spatially resolved transcriptomics data equipping participants to critically plan their experimental design and analyses...

Virtual

9 September - 12 September 2024

Chemical biology 2024

Edit

September 09, 2024 00:002024ConferenceEMBL Heidelberg, Virtual

Description OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Conference overview The conference sets the stage for the dissemination and exchange of new developments in diverse emerging fields within chemical biology It is the largest and longest standing conference in the field being a platform for inspiration collaboration and networking for researchers in academia and industry We aim to provide the possibility for every chemical biologist to meet and discuss with peers topics ranging from tool development to biological applications from computational protein design to new drug modalities Session topics Chemical biology meets drug discovery Chemical biology of posttranslational modifications Non coding RNA and unusual RNA products Lipids and lipidation Chemical biology technologies Peptide therapeutics and computational protein design Epigenetic and gene editing tools What past participants say about the conference The conference was very well organised with an amazing programme great speakers and it has proved a valuable source of information A very challenging and worthwhile experience Rosalba Sortino Institute for Bioengineering of Catalonia Spain The EMBO Chemical Biology Workshop 2020 was super Inspiring talks and very well organised I had the opportunity to give a short presentation and got interesting feedback and discussion Ma Florencia Sanchez Institute for Biochemistry University of Frankfurt Germany This event has been granted the following EMBO sustainability badge Grade 2 of 3 Speakers Keynote speakers Craig Crews Yale University USA Kai Johnsson Max Planck Institute for Medical Research Germany Sarah O Connor Max Planck Institute for Chemical Ecology Germany Speakers Luc Brunsveld Eindhoven University of Technology The Netherlands Yong Xiang Chen Tsinghua University China Bruno Correia EPFL Switzerland Bianxiao Cui Stanford University USA Maria Duca French National Centre for Scientific Research CNRS France Deborah Fass Weizmann Institute of Science Israel Pau Gorostiza Institute for Bioengineering of Catalonia Spain Ulrich Schopfer Novartis Switzerland Benjamin Schumann The Francis Crick Institute UK Sarah Slavoff Yale University USA Mikiko Sodeoka RIKEN Japan Thorsten Stafforst University of T bingen Germany Kristian Str mgaard University of Copenhagen Denmark Daniel Summerer TU Dortmund University Germany Olalla V zquez University of Marburg Germany Georg Winter CeMM Austria Christina Woo Harvard University USA Scientific organisers Yimon Aye Ecole Polytechnique Federale de Lausanne Switzerland Bryan Dickinson The University of Chicago USA Maja K hn University of Freiburg Germany Conference organisers Sophie Dutzi EMBL Heidelberg Germany Programme Are you on social media Post using EMBOChemBio and don t forget to tag EMBLEvents Please note that the programme is subject to change Some speakers may need to join virtually to give their talk For registered participants recorded talks will be accessible on demand for 2 weeks after the end of the event unless indicated otherwise Day 1 Monday 9 September 2024 Time Europe Berlin Session11 00 13 00 Registration and light refreshments13 00 13 10Opening remarksSession 1 Chemical Biology meets drug discoveryChairs Chayasith Uttamapinant Vidyasirimedhi Institute of Science and Technology Thailand andMilena Schuhmacher EPFL Switzerland13 10 13 45Targeted protein degradation via molecular gluesGeorg Winter CeMM Austria13 45 14 00Selective OSBP inhibition attenuates retrograde trafficking by triggering partial Golgi degradationNianzhe He Technical University of Denmark Denmark14 00 14 35Ligands for the E3 ligase substrate adapter cereblonChristina Woo Harvard University USANot available on demand14 35 15 05Coffee Break and meet the speakers15 05 15 40Targeted Therapies chemical biology for precision medicines Ulrich Schopfer Novartis SwitzerlandNot available on demand15 40 15 55Transferrin Receptor Targeting Chimeras TransTACs for targeted membrane and extracellular protein degradationXin Zhou Dana Farber Cancer Institute Harvard Medical School USANot available on demand15 55 16 10Chemoproteomic mode of action analysis of protein kinase degradersNicola Berner Technical University Munich Germany16 10 16 45Flash talk session even numbers 38 Archita Agrawal 46 Pavel Kielkowski 72 Carla Duval 78 Kyohhei Fujita 104 Eszter Kozma 108 Henriette L mmermann 126 Qunxiang Ong 130 Julia Pols 146 Nicholas Southern 150 Colin Swenson 154 Max Unger 158 Frederik Weber 160 Mingxuan Wu16 45 18 30Poster session 1 even numbers 18 30 19 30Keynote Session Induced Proximity Exploring new therapeutic modalitiesCraig Crews Yale University USA virtual Not available on demand19 30 21 00Canteen dinner Day 2 Tuesday 10 September 2024 Time Europe Berlin SessionSession 2 Chemical Biology of posttranslational modificationsChair Christina Woo Harvard University USA09 00 09 35EMBO Young Investigator LectureChemical precision tools to dissect protein glycosylationBen Schumann Francis Crick Institute UKNot available on demand09 35 09 50Chemical tools to study the SHP2 phosphatase in immune cellsCatia Pierotti University of Freiburg GermanyNot available on demand09 50 10 25Synthesis and bio functional application of diverse phosphorus containing proteins peptidesYong Xiang Chen Tsinghua University ChinaNot available on demand10 25 10 55Coffee Break and meet the editorsSession 3 Non coding RNA and unusual RNA productsChair Peng Zou Peking University China10 55 11 30Small molecules targeting non coding RNAsMaria Duca CNRS France11 30 11 45Accelerating protein engineering with viral based in vivo screening and evolution technologiesBryan Dickinson University of Chicago USA11 45 12 20Dissecting the functional implications of alternative start codonsSarah Slavoff Yale University USA12 20 14 00Lunch and meet the speakersSession 4 Lipids and lipidationChair Xuyu Liu The University of Sydney Australia14 00 14 35Live Cell Imaging Using Raman TagMikiko Sodeoka RIKEN JapanNot available on demand14 35 14 50Deconvoluting protein S acylation by the ZDHHC enzyme family in macrophagesAnne Schuhmacher Imperial College London UK14 50 15 05A genetically encoded photoproximity labeling approach for mapping protein territoriesNir Hananya Technion Israel Institute for Molecular Genetics Israel15 05 15 20Controlling properties composition and function of biomolecular condensates with a micropeptide killswitch Yaotian Zhang Max Planck Institute for Molecular Genetics Germany15 20 16 00Flash talk session odd numbers 41 Fernando Banales Mejia 43 Lydia Barber 65 Mariska de Munnik 81 Sara Gomes 85 Bj rn Hanf 101 Seungwoo Kim 113 Ella Livnah 115 Abbie Macmillan Jones 127 Gamze Nur Yapici 131 Lena Quambusch 141 Angelika Seliwjorstow 145 Daria Sokolova 153 Ricarda Toerner 155 Martin Witte 163 Masahiko Yoshimura 167 Taja Zeleznik Ramuta16 00 17 45Poster session 2 odd numbers 17 45 18 00Break18 00 19 00Keynote Session Recording the physiological history of cells with chemical labelingKai Johnsson Max Planck Institute for Medical Research GermanyNot available on demand19 00 21 00Canteen Dinner21 00 22 00After dinner drinks in ATC Foyer Day 3 Wednesday 11 September 2024 Time Europe Berlin SessionSession 5 Chemical Biology TechnologiesChairs Sarah Slavoff Yale University USAandOlalla Vazquez University of Marburg Germany09 00 09 35 Photoswitchable drugs to control neuronal activity with light from individual synapses to brain wavesPau Gorostiza Institute for Bioengineering of Catalonia SpainNot available on demand09 35 09 50Reprogramming protein translation in spatiotemporal stress responseDalu Chang cole Polytechnique F d rale de Lausanne Switzerland09 50 10 25Membrane curvature mediated integrin activation and drug discoveryBianxiao Cui Stanford University USA10 25 10 55Coffee Break and meet the editors10 55 11 30Modulating mucin glycoproteins for health maintenance and disease therapyDeborah Fass Weizmann Institute of Science Israel11 30 11 45An improved Caprola variant for recording calcium activityNicola Porzberg Max Planck Institute for Medical Research Germany11 45 12 00Genetically encoded photocatalysis for spatially restricted profiling of biomoleculesPeng Zou Peking University China12 00 12 15Targeting the fine tuned and localized production of reactive oxygen species by inhibiting NADPH oxidasesSara Marchese University of Pavia Italy12 15 14 00Lunch and meet the speakersSession 6 Peptide therapeutics and computational protein designChairs Andy Wilson University of Birmingham UKandGeorg Winter CeMM Austria14 00 14 35Targeting protein protein interactions in receptor complexesKristian Stromgaard University of Copenhagen Denmark14 35 14 50Unveiling hidden functions of post dietary electrophilic modifications in platelet pathophysiology using integrated phenotypic and chemoproteomic approachesXuyu Liu The University of Sydney Australia14 50 15 05A druggable ubiquitin like conjugation system controls hippo pathway activityMaya Bulos The Scripps Research Institute USANot available on demand15 05 17 30Poster session 3 all numbers 17 30 18 05Chemical biology approaches for a quantitative understanding of PPI stabilization or how to identify molecular gluesLuc Brunsveld Eindhoven University of Technology The NetherlandsNot available on demand18 05 18 20Understanding and manipulating protein protein interactions of Aurora A Kinase employing intrinsically disordered regionsAndy Wilson University of Birmingham UK18 20 18 55Expanding the universe of functional proteins by computational designBruno Correia Ecole Polytechnique Federale de Lausanne Switzerland19 00 21 00Conference Dinner21 00 00 00Conference Party with Band Day 4 Thursday 12 September 2024 Time Europe Berlin SessionSession 7 Epigenetics and genetic editing toolsChair Patrick Rabe University of Oxford UK09 00 09 35Designer proteins for decoding the function of epigenetic DNA modificationsDaniel Summerer TU Dortmund University GermanyNot available on demand09 35 09 50A tunable and versatile chemogenetic near infrared fluorescent reporterLina El Hajji Sorbonne Universit cole Normale Sup rieure Universit PSL CNRS France09 50 10 25Chemical biology tools for microbiologyOlalla Vazquez Marburg University GermanyNot available on demand10 25 10 55Coffee Break and meet the speakers10 55 11 30Frontiers in site directed RNA editingThorsten Stafforst University of Tubingen Germany11 30 11 45Recombinase controlled multiphase condensates for CRISPR based diagnosticsChayasith Uttamapinant Vidyasirimedhi Institute of Science and Technology Thailand11 45 12 45Keynote Session Chemistry of natural product pathwaysSarah O Connor Max Planck Institute for Chemical EcologyGermanyNot available on demand12 45 13 00Poster prize announcements closing remarks13 00 13 30Packed Lunch and departure Practical information Registration fees and abstract submission On site registration fees include admission conference materials meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Virtual registration fees include access to all of the talks livestreamed and on demand and facility to submit questions On site Academia 450On site PhD Student 350On site Industry 750Virtual Academia 200Virtual PhD Student 150Virtual Industry 275 A letter to support your visa application will be issued on request once payment of the registration fee is confirmed We recommend that you book your visa appointment as soon as possible to avoid any delay with your visa application Accredited journalists may be eligible to register for complimentary press registration Registrants may be required to provide accreditation or equivalent proof of press membership after registration Please contact events embl de for more information Please note that we do not offer complimentary registrations for editors of scientific journals Confirmation and payment Registration will be on a first come first served basis Your place can only be confirmed after payment of the registration fee If you are added to our waiting list please consider taking advantage of our offerings to participate virtually On site participants Types of payments accepted are international bank transfers and credit card payments Virtual participants We are only able to accept card payments In exceptional cases we can accept bank transfers Please contact events embl de for details Abstract submission Only participants registering to attend the on site event are eligible to submit an abstract Abstracts will not be accepted from virtual participants After registration you can submit your abstract via a separate link that will be provided in the email confirmation Alternatively you can access the link on the confirmation page directly after registering The same login credentials are used for both processes Please note Abstract body The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised Title The title should not exceed 20 words Only the first word of the title should start with a capital letter and the rest should be lowercase Authors and affiliations Please fill in the author s details as requested in the online form The compulsory fields are First Name Last Name Organisation Name Affiliation or Company Country and Email Kindly mark only one author in the role of First Author and please don t forget to indicate who will be the Presenter Please enter your co authors correctly via the system by adding accounts together with their organisation institute Do not copy paste them into the body of the abstract text as they will not be indexed in the abstract book Presentation types When submitting your abstract you can apply for an oral or poster presentation A selection process will take place with the results announced 2 3 weeks after the abstract submission deadline For detailed instructions on how to submit a conference abstract follow the instructions provided in this video Please check our FAQs pages for further information on how to submit an abstract Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of both registration fee waivers and travel grants These are available for on site participants at EMBL Conferences and EMBO EMBL Symposia and for on site and virtual participants at EMBO Workshops We are currently working on securing funding for all virtual participants and ask that you please apply for financial assistance for both on site and virtual participation Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course or conference Travel grant The travel grant will cover the cost of travel to an on site event airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 500 for any participant travelling to an EMBO Workshop up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Workshop up to 700 for any participant working in Croatia Czech Republic Estonia Greece Hungary Italy Lithuania Luxembourg Poland Slovenia and Turkey travelling to an EMBO Workshop Registration fees are only covered for EMBO Workshops The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant EMBO Workshops only For EMBO Workshop participants with children there is the possibility to apply for a childcare grant to offset child care costs incurred by participants or speakers when participating at a conference Eligible costs include fees for a baby sitter or child care facility travel costs for a caregiver or travel costs for taking the child to the meeting etc Please note that priority will be given to early stage researchers A maximum amount of 500 can be awarded per participant applying for an EMBO childcare grant In order to apply for this grant for EMBO Workshops you must be registered by the abstract submission deadline Application On site participants You may apply for financial assistance when submitting your abstract In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Virtual participants If you are attending virtually you can apply for financial assistance in the submission portal by the abstract deadline Read the instructions on how to apply for financial assistance Only submissions for financial assistance will be accepted Presentation abstracts cannot be submitted here and will be declined In your application you will be asked to summarise your current work answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Selection The scientific organisers will select the recipients of all financial assistance during the abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details View our list of external funding opportunities and information on attending a conference as an event reporter For further information about financial assistance please refer to the FAQ page Accommodation and travel Accommodation is not included in the conference registration fee As further changes in our events are possible you should book flights trains and hotels with flexible options and favourable cancellation conditions The hotels below have rooms on hold for participants until 12 August 2024 in some cases at special rates Please email the hotel directly quoting the booking code CHB24 01 to confirm the exact price of the room Hotel AnlageHotel ibis HeidelbergMeininger HeidelbergB B HotelHotel ISGPremier Inn Heidelberg CityHilton Heidelberg Travel information For travel information please see here If you are travelling to the conference within Germany then you are eligible for the Deutsche Bahn Event Ticket called the Veranstaltungsticket in German This will result in a lower ticket price if your travel distance to Heidelberg is more than 100 km You need to provide proof of your event attendance when purchasing the ticket For more information in English see here or in German see here You can book your ticket here Conference shuttle buses Conference shuttle buses are free of charge for participants and depart from designated bus stops near the hotels to EMBL and back mornings and evenings Please find the conference shuttle bus schedule here 28 August 2024 The bus stops for this conference are Staycity Aparthotel Speyerer Str 7 Kurf rsten Anlage Opposite Main Train Station Premier Inn Kurf rsten Anlage 23 Leonardo Hotel Heidelberg City Center Bergheimer Str 63 Neckarm nzplatz Heidelberg Tourist Information Peterskirche Bus stop Hilton Hotel Kurf rsten Anlage 1 ISG Hotel Im Eichwald 19 View Conference shuttle bus stops and hotels in a larger map Please note that not every bus stop will be used for every event Further details Address EMBL Meyerhofstra e 1 69117 Heidelberg Germany For more information about accommodation and travel please refer to the FAQ page On site information Catering All meals and coffee breaks are included in the registration fee Our catering staff will prepare a wide variety of vegetarian meals meat and fish dishes soups pasta fresh fruit and vegetables as well as a variety of desserts Please wear your badge at all times when serving yourself No food or drinks are allowed in the auditorium Charging lockers There are lockers available next to the stairs leading down into the Auditorium You will find some of those equipped with sockets to charge your smartphone tablet etc Electricity and charging station In most places the electricity is 220 volts AC 50 cycles An adaptor and a plug that fits the German socket may be needed for your appliances laptop i e American Japanese etc A USB charging station for electronic devices is available at the registration desk EMBL merchandise If you are interested in purchasing EMBL merchandise products presented in the glass display in the registration area please email the EMBL shop to place an order or get in contact with your Course Organiser Kindly note the EMBL shop is only open upon request and all purchases must be made in cash Euros only Health and safety notes Please read EMBL s COVID 19 safety policy for on site events Do not smoke in any EMBL building Eating and drinking is prohibited in the Auditorium and all laboratories Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required The first aid room is located next to the ATC Registration Desk room 10 205 Dial the Emergency number 222 from any EMBL internal phone only Where is the accident What happened How many injured Emergency number 06221 387 7821 from mobile phones Please report all accidents to the conference officer at the registration desk In case of fire Press the nearest fire alarm button or the Emergency number 222 from any internal phone A loud fire alarm will go off if an evacuation is required On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting points Do not use the lifts Beyond first aid Please remember to bring your own medication if needed to the conference Note that the next pharmacy is a 4 minute drive from the EMBL but for many medications you will be required to see a doctor to get a prescription Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg In any case the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary Internet Wi Fi is available on campus using the EMBL Events network and the event specific password which will be provided on site The eduroam network secure worldwide roaming access service developed for the international research and education community is also available Lost and found Lost and Found items are kept at the registration desk until the end of the conference Luggage There are lockers available on site to store your luggage which require a 2 EURO coin to operate There is another luggage room on level E0 which is free to use but remains unlocked during the conference Nursing room There is a nursing room available in the ATC Rooftop Lounge on level A29 Photography During the conference an EMBL Photographer may be taking photos If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Printing We can help to print your boarding pass train ticket Please send it to events embl de and collect your print outs at the registration desk Room for prayer yoga and meditation There is a room for prayer meditation and yoga located on level E0 behind the Auditorium Please be respectful of others using the room Sightseeing A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing Travel to and from the venue During the event we provide conference shuttle buses to and from EMBL In addition there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time Information on the conference shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page Useful German expressions HelloHalloGoodbyeAuf Wiedersehen formal Tsch ss informal Good morningGuten MorgenGood afternoonGuten TagGood eveningGuten AbendGood nightGute NachtI m sorryEs tut mir leidExcuse me Entschuldigen SieHow are you Wie gehts I m fine thanks And you Mir geht es gut danke Und Dir Ihnen What is your nameWie hei en Sie formal Wie hei t du informal My name is Ich hei e Do you speak EnglishSprechen Sie englisch I don t understandIch verstehe nichtPlease speak more slowlyK nnen Sie bitte langsamer sprechenThank youDankesch nWhere is the toilet Wo ist die Toilette Please call me a taxiBitte rufen Sie mir ein TaxiHow do I get to Wie komme ich zum zur A beer two beers pleaseEin Bier zwei Bier bitteA glass of red white wine pleaseEin Glas Rot Weisswein bitteThe menu pleaseDie Speisekarte bitteIs there a local speciality Gibt es eine Spezialit t aus dieser Gegend I m vegetarianIch bin VegetarierIt was deliciousEs war hervorragendThe bill pleaseDie Rechnung bitteI have a headacheIch habe KopfschmerzenI have a sore throatIch habe HalsschmerzenMy stomach hurtsIch habe MagenschmerzenI m allergic toIch bin allergisch gegenI need a doctor who speaks EnglishIch brauche einen Arzt der englisch spricht Virtual participation What s included Access to all the livestreamed talks Video library of the recorded talks during the event and for two weeks afterwards Please note at the request of individual speakers some talks are not recorded Facility to submit questions Please note that only on site participants are able to submit abstracts and participate in the poster sessions Event platform We are using an event platform for this conference More information about the platform will be shared ahead of the conference Guidelines Do not broadcast the conference to unregistered participants You are encouraged to tweet and post about the event Tweet unless the speaker specifically says otherwise but be mindful of unpublished data Please do not capture transmit or redistribute data presented at the meeting Additional information can be found in our Code of Conduct Health and well being It is important to stay healthy and move around especially when you are attending an event virtually We have put together a few coffee break stretches and yoga videos in the conference platform for you to enjoy during the event How to ask questions Please use the Q A function in the event platform If you have any other questions you can go to the Help Desk in the event platform Click on more on the top menu and click Help Desk Time zone The programme is planned based on the Europe Berlin time zone unless otherwise stated Please take your time zone into consideration when planning your attendance Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for participants page COVID 19 related questions COVID 19 information for on site events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Bronze sponsor Event sponsor Sirius Fine Chemicals SiChem Event supporters Media partners EMBO Reports an EMBO Press journal FEBS Journal International Union of Biochemistry and Molecular Biology Medinformatics a Bon View Publishing journal Open Biology a Royal Society journal Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl org for further information on sponsoring possibilities If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 Leaderboard 728 90...

Yimon Aye, Bryan Dickinson, Maja Köhn

EMBO Workshop

EMBL Heidelberg, Virtual

9 September - 16 September 2024

Membrane protein expression, purification, and characterisation 3 (mPEPC3)

Edit

September 09, 2024 00:002024CourseEMBL Hamburg

Description OverviewSpeakers and TrainersPreliminary pogrammePractical informationSponsorsMedia kit Overview Course overview This hands on course focuses on training participants on how to work with membrane proteins troubleshooting in the wet lab during solubilisation and reconstitution and conducting experiments at the beamlines and during early stages of cryoEM screening To perform integrated structural biology experiments well equipped crystallisation and cryo EM facilities as well as beamlines for SAXS for time resolved macromolecular crystallography will be used Audience Applicants in the early stage of their research careers mid to end of PhD project or early postdoctoral career will be given preference based on their application We also welcome applications from non academic labs Modules Transient transfection of mammalian cells for recombinant Integral Membrane Proteins IMP expression Generation of stable mammalian cell lines for IMP production Solubilisation and quality control of IMPs Reconstitution of membrane proteins Native mass spectrometry on endocytic adaptor proteins SAXS approaches for IMPs Time resolved X ray diffraction setups for going 4D and sample delivery for studying enzymatic reactions Time resolved serial crystallography of integral membrane proteins in lipidic cubic phase Negative stain a grid preparation and data recording b data analysis and 3D reconstruction Membrane protein modelling Learning outcomes Participants will enhance their knowledge and skills in structural studies of membrane proteins including expression and purification reconstitution biophysical characterisation and structural determination of integral membrane proteins Please see EMBL s COVID 19 safety recommendations for testing and other requirements to attend this on site course Speakers and Trainers Lucia Banci University of Florence Italy Kim Bartels University Medical Center Hamburg Eppendorf Germany Isabel Bento EMBL Hamburg Germany Clement Blanchet EMBL Hamburg Germany Osvaldo Burastero EMBL Hamburg Germany Lucas Defelipe EMBL Hamburg Germany Juan Du Van Andel Institute USA Jens Frauenfeld Salipro Biotech AB Sweden Melissa Graewert EMBL Hamburg Germany Steve Harborne Peak Proteins UK Rory Hennell James Centre for Structural Systems Biology Hamburg Germany Kevin Janson Center for Free Electron Laser Science CFEL Deutsches Elektronen Synchrotron DESY Germany Syma Khalid University of Oxford UK Janine Denise Kopicki Centre for Structural Systems Biology Hamburg Germany Jan Kosinski EMBL Hamburg Germany Kirill Kovalev EMBL Hamburg Germany Thomas Marlovits Universit tsklinikum Hamburg Eppendorf and Centre for Structural Systems Biology Germany Melanie McDowell Max Planck Institute of Biophysics Germany Pedram Mehrabi Max Planck Institute for the Structure and Dynamics of Matter Germany Amit Meir Ben Efraim University of Glasgow United kingdom Dmitry Molodenskiy EMBL Hamburg Germany Stephen Muench University of Leeds UK Thomas Mulvaney Centre for Structural Systems Biology Hamburg Germany Stephan Niebling EMBL Hamburg Germany Arwen Pearson Universit t Hamburg and Max Planck Institute for the Structure and Dynamics of Matter Germany Martin Pelosse EMBL Grenoble France Kim Remans EMBL Heidelberg Germany Jennifer Rothe Centre for Structural Systems Biology Hamburg Germany David Ruiz EMBL Hamburg Germany Mikhail Savitski EMBL Heidelberg Germany Wiebke Schultze Centre for Structural Systems Biology Hamburg Germany Eike Schulz Universit tsklinikum Hamburg Eppendorf Germany Markus Seeger University of Zurich Switzerland Azadeh Shahsavar University of Copenhagen Denmark Bettina Siebers University of Duisburg Essen Germany Henning Tidow Universit t of Hamburg Germany Charlotte Uetrecht Centre for Structural Systems Biology and Leibniz Institute of Virology Germany Katharina Veith EMBL Hamburg Germany David von Stetten EMBL Hamburg Germany Yexin Xie EMBL Heidelberg Germany Scientific Organisers Maria Garcia EMBL Hamburg Germany Simon Mortensen EMBL Hamburg Germany Kim Remans EMBL Heidelberg Germany Angelica Struve EMBL Hamburg Germany Henning Tidow Universit t Hamburg Germany Course Organisers Maria Mercedes Bacadare Goitia Course and Conference Team Lead EMBL Heidelberg Germany Swetlana Krez EMBL Heidelberg Germany Preliminary pogramme Are you on social media Post using EMBOPEPC and don t forget to tag EMBLEvents Some pre course work such as watching pre recordings protocol reading and computational exercises with estimated time 0 10 hours will be required and will be shared in advance of the course Day 1 Monday 9 September 2024 Time Europe Berlin SessionLocation09 00 09 30RegistrationCentre for StructuralSystems Biology CSSB Building 15 Ground Floor Foyer entrance next to Lecture Hall 09 30 09 45WelcomeMaria Garcia Alai EMBL Hamburg GermanyCentre for StructuralSystems Biology CSSB Building 15 Lecture Hall09 45 10 30Lecture 1 Recombinant protein production in eukaryotic cells Introduction to practical session AKim Remans EMBL Heidelberg GermanyCentre for StructuralSystems Biology CSSB Building 15 Lecture Hall10 30 11 30Lecture 2 Genome engineering for protein production in mammalian cells Introduction to practical session BMartin Pelosse EMBL Grenoble FranceCentre for StructuralSystems Biology CSSB Building 15 Lecture Hall11 30 11 45Coffee breakEMBL Hamburg Building 48e Second Floor Terrace11 45 12 45Lecture 3 Native from native unique bacterial systems at the service of macromolecular bioimaging Introduction to practical session DAmit Meir Ben Efraim Glasgow University UKCentre for StructuralSystems Biology CSSB Building 15 Lecture Hall12 45 14 00Lunch breakDESY Canteen Building 914 00 15 00Lecture 4 Fe siderophore transport and the power stroke mechanism in ABC transporters Introductionto practical session CHenning Tidow Universit t of Hamburg GermanyCentre for StructuralSystems Biology CSSB Building 15 Lecture Hall15 00 16 00Flash Talks PresentationsCentre for StructuralSystems Biology CSSB Building 15 Lecture Hall16 00 16 30Coffee breakEMBL Hamburg Building 48e Second Floor Terrace16 30 17 30Lecture 5 Integrative modelling tools for Cryo EMThomas Mulvaney Maya Topf Lab Centre for Structural Systems Biology and Leibniz Institute of Virology GermanyCentre for StructuralSystems Biology CSSB Building 15 Lecture Hall17 30 18 30Poster session 1Centre for StructuralSystems Biology CSSB Building 15 Ground floor Foyer18 30 21 00Welcome dinner Day 2 Tuesday 10 September 2024 Time Europe Berlin SessionLocation08 50 09 00Overview of the dayCentre for StructuralSystems Biology CSSB Bulding 15 Ground Floor Foyer entrance next to Lecture Hall 09 00 10 00Lecture 6 Native mass spectrometry in biophysical and structural characterization of protein complexes Introduction to practical session ECharlotte Uetrecht Centre for Structural Systems Biology and Leibniz Institute of Virology GermanyCentre for StructuralSystems Biology CSSB Building 15 Lecture Hall10 00 13 00Parallel practical session 1 with short coffee break Practical session A1 Transfection of HEK293F cells for recombinantprotein expression and analysis of expression of integral membrane proteins IMPs Practical session B CRISPR Cas editing of cell lines for integral membrane protein expressionPractical session C Quality control Solubilisation and biophysical characterisation of membrane proteinsPractical session E Native mass spectrometry on membrane adaptor proteins complexesPractical F SAXS on membrane proteinsCentre for StructuralSystems Biology CSSB Building 15 EMBL Laboratories 01 228 and 02 228 EMBL Hamburg 48e Building Ground Floor P12 beamline13 00 14 00Lunch breakDESY Canteen Building 914 00 17 00Parallel practical session 2 with short coffee break Practical session A1 Transfection of HEK293F cells for recombinantprotein expression and analysis of expression of integral membrane proteins IMPs Practical session B CRISPR Cas editing of cell lines for integral membrane protein expressionPractical session C Quality control Solubilisation and biophysical characterisation of membrane proteinsPractical session E Native mass spectrometry on membrane adaptor proteins complexesPractical F SAXS on membrane proteinsCentre for StructuralSystems Biology CSSB Building 15 EMBL Laboratories 01 228 and 02 228 EMBL Hamburg 48e Building Ground Floor P12 beamline17 00 18 00Flash Talks Presentations Centre for StructuralSystems Biology CSSB Building 15 Lecture Hall18 00 19 30Poster session 2Centre for StructuralSystems Biology CSSB Building 15 Ground floor Foyer19 30 22 00Dinner Day 3 Wednesday 11 September 2024 Time Europe Berlin SessionLocation08 50 09 00Overview of the dayCentre for StructuralSystems Biology CSSB Bulding 15 Ground Floor entrance next to Lecture Hall 09 00 10 00Lecture 7 Biophysical proteomics Mikhail Savitski EMBL Heidelberg GermanyCentre for StructuralSystems Biology CSSB Building 15 Lecture Hall10 00 13 00Parallel practical session 3 with shortcoffee break Practical session A1 Transfection of HEK293F cells for recombinant protein expression and analysis of expression of integral membrane proteinsPractical session B CRISPR Cas editing of cell lines for integral membrane protein expressionPractical session C Quality control Solubilisation and biophysical characterisation of membrane proteinsPractical session D Reconstitution technologies of membrane proteins liposomes and artificial bilayersPractical session J Bioinformatics AI tools and membrane protein modellingCentre for StructuralSystems Biology CSSB Building 15 EMBL Laboratories 01 228 and 02 228 13 00 14 00Lunch breakDESY Canteen Building 914 00 14 45Lecture 8 Same in the membrane The Salipro Platform for GPCRs and Ion Channels for Drug Development Jens Frauenfeld Salipro Biotech AB SwedenCentre for StructuralSystems Biology CSSB Building 15 Lecture Hall14 45 15 00Coffee breakEMBL Hamburg Building 48e Second Floor Terrace15 00 18 00Parallel practical session 4Practical session A1 Transfection of HEK293F cells for recombinant protein expression and analysis of expression of integral membrane proteinsPractical session C Quality control Solubilisation and biophysical characterisation of membrane proteinsPractical session E Native mass spectrometry on membrane proteins complexesPractical session G Time resolved X ray crystallography setups for going 4D and sample delivery for studying enzymatic reactionsPractical session I Cryo EM grid preparation data recording and 3D reconstructionCentre for StructuralSystems Biology CSSB Building 15 EMBL Laboratories 01 228 and 02 228 EMBL Hamburg 48e Building Ground Floor P14 EH2 beamline18 30 21 00Dinner Day 4 Thursday 12 September 2024 Time Europe Berlin SessionLocation08 50 09 00Overview of the dayCentre for StructuralSystems Biology CSSB Bulding 15 Ground Floor entrance next to Lecture Hall 09 00 12 00Parallel practical session 5 with short coffee break Practical session A2 Transfection of HEK293F cells for recombinant protein expression and analysis of expression of integral membrane proteinsPractical session B CRISPR Cas editing of cell lines for integral membrane protein expressionPractical session F SAXS on membrane proteinsPractical session G Time resolved X ray crystallography setups for going 4D and sample delivery for studying enzymatic reactionsPractical session H Time resolved serial crystallography of integral membrane proteins in lipidic cubic phaseCentre for StructuralSystems Biology CSSB Building 15 EMBL Laboratories 01 228 and 02 228 EMBL Hamburg 48e Building Ground Floor P12 P14 EH2 beamline12 00 13 00Lecture 9 Membrane protein purification for single particle Cryo EM studies Juan Du Van Andel Institute USACentre for StructuralSystems Biology CSSB Building 15 Lecture Hall13 00 14 00Lunch breakDESY Canteen Building 914 00 17 00Parallel practical session 6Practical session A2 Transfection of HEK293F cells for recombinant protein expression and analysis of expression of integral membrane proteinsPractical session B CRISPR Cas editing of cell lines for integral membrane protein expressionPractical session C Quality control Solubilisation and biophysical characterisation of membrane proteinsPractical session F SAXS on membrane proteinsPractical session G Time resolved X ray crystallography setups for going 4D and sample delivery for studying enzymatic reactionsCentre for StructuralSystems Biology CSSB Building 15 EMBL Laboratories 01 228 and 02 228 EMBL Hamburg 48e Building Ground Floor P12 P14 EH2 beamline17 00 17 30Coffee breakEMBL Hamburg Building 48e Second Floor Terrace17 30 18 30Lecture 10 Unlocking the Structural Basis for the Inhibition of amino acid Transporters Azadeh Shahsavar University of Copenhagen DenmarkCentre for StructuralSystems Biology CSSB Building 15 Lecture Hall18 30 21 00Dinner Day 5 Friday 13 September 2024 Time Europe Berlin SessionLocation08 50 09 00Overview of the day09 00 10 00Lecture 11 Unraveling the Unique Properties of Archaeal Enzymes and Their Potential in Industrial Biocatalysis Bettina Siebers Universit t Duisburg Essen GermanyCentre for StructuralSystems Biology CSSB Building 15 Lecture Hall10 00 13 00Parallel practical session 7 with short coffee break Practical A2 Transfection of HEK293F cells for recombinant protein expression and analysis of expression of integral membrane proteinsPractical G Time resolved X ray crystallography setups for going 4D and sample delivery for studying enzymatic reactionsPractical H Time resolved serial crystallography of integral membrane proteins in lipidic cubic phasePractical F SAXS on membrane proteinsPractical J Bioinformatics AI tools and membrane protein modellingCentre for StructuralSystems Biology CSSB Building 15 EMBL Laboratories 01 228 and 02 228 EMBL Hamburg 48e Building Ground Floor P12 P14 beamline13 00 14 00Lunch breakDESY Canteen Building 914 00 15 00Lecture 12 Cryo EM on secretion systems Introduction to practical session 9Thomas Marlovits UKE Hamburg and Centre for Structural Systems Biology GermanyCentre for StructuralSystems Biology CSSB Building 15 Lecture Hall15 00 16 00Lecture 13 Quality control for membrane proteins Melanie McDowell Max Planck Institute of Biophysics Frankfurt am Main GermanyCentre for StructuralSystems Biology CSSB Building 15 Lecture Hall16 00 16 30Coffee breakEMBL Hamburg Building 48e Second Floor Terrace16 30 17 30Lecture 14 Simulating bacterial membrane proteins the importance of incorporating biological complexity Syma Khalid University of Oxford United KingdomCentre for StructuralSystems Biology CSSB Building 15 Lecture Hall17 30 18 30Lecture 15 Introduction to TR crystallography Arwen Pearson Universit t Hamburg and Max Planck Institute for the Structure and Dynamics of Matter GermanyCentre for StructuralSystems Biology CSSB Building 15 Lecture Hall19 00 22 00Dinner Day 6 Saturday 14 September 2024 Time Europe Berlin SessionLocation08 50 9 00Overview of the day09 00 10 00Lecture 15 Sybodies and membrane proteins happy together Markus Seeger University of Z rich SwitzerlandCentre for StructuralSystems Biology CSSB Building 15 Lecture Hall10 00 13 00Parallel practical session 8 with short coffee break Practical A1 Transfection of HEK293F cells for recombinant protein expression and analysis of expression of integral membrane proteinsPractical D Reconstitution technologies of membrane proteins liposomes and artificial bilayersPractical I Cryo EM grid preparation data recording and 3D reconstructionPractical J Bioinformatics AI tools and membrane protein modellingPractical H Time resolved serial crystallography of integral membrane proteins in lipidic cubic phaseCentre for StructuralSystems Biology CSSB Building 15 EMBL Laboratories 02 228 CryoEM facility Basement EMBL Hamburg 48e Building Ground Floor P14 beamline13 00 14 00Lunch breakDESY Canteen Building 914 00 15 00Lecture 17 Current challenges and solutions for sample preparation in single particle cryo EM Stephen Muench University of Leeds UKCentre for StructuralSystems Biology CSSB Building 15 Lecture Hall15 00Free afternoon Excursion in Hamburg Day 7 Sunday 15 September 2024 Time Europe Berlin SessionLocation09 50 10 00Overview of the day10 00 13 00Parallel practical session 9 with short coffee break Practical A2 Transfection of HEK293F cells for recombinant protein expression and analysis of expression of integral membrane proteinsPractical D Reconstitution technologies of membrane proteins liposomes and artificial bilayersPractical H Time resolved serial crystallography of integral membrane proteins in lipidic cubic phasePractical I Cryo EM grid preparation data recording and 3D reconstructionPractical J Bioinformatics AI tools and membrane protein modellingCentre for StructuralSystems Biology CSSB Building 15 EMBL Laboratories 02 228 CryoEM facility Basement EMBL Hamburg 48e Building Ground Floor P14 beamline13 00 14 00Lunch breakDESY Canteen Building 914 00 15 00Lecture 18 in cell NMRLucia Banci University of Florence ItalyCentre for StructuralSystems Biology CSSB Building 15 Lecture Hall15 00 16 00Meet the expert session 1 Pharmaceutical industry perspective on membrane protein research Dr Harm Jan Snijder Astrazeneca Lessons from membrane protein production for drug discovery projects Dr Julius Nitsche Proteros Biostructures GmbHCentre for StructuralSystems Biology CSSB Building 15 Lecture Hall16 00 16 30Coffee breakEMBL Hamburg Building 48e Second Floor Terrace16 30 17 30Lecture 19 Visualizing nuclear pore complexes through cryo electron tomography and structural modeling Introduction to practical session 10Jan Kosinski EMBL Hamburg GermanyCentre for StructuralSystems Biology CSSB Building 15 Lecture Hall17 30 18 30Lecture 20 Production of Folded and Functional Membrane Proteins for Drug Discovery Steve Harborne Peak Proteins UKCentre for StructuralSystems Biology CSSB Building 15 Lecture Hall18 30 21 00Pizza dinner followed by a roundtable discussion on the different aspects of responsible conduct of researchCentre for StructuralSystems Biology CSSB Building 15 Lecture Hall Ground Floor Day 8 Monday 16 September 2024 Time Europe Berlin SessionLocation08 50 09 00Overview of the day09 00 12 00Parallel practical session 10 with short coffee break Practical D Reconstitution technologies of membrane proteins liposomes and artificial bilayers Practical E Native mass spectrometry on membrane adaptor proteins complexesPractical G Time resolved X ray crystallography setups for going 4D and sample delivery for studying enzymatic reactionsPractical I Cryo EM grid preparation data recording and 3D reconstructionPractical J Bioinformatics AI tools and membrane protein modellingCentre for StructuralSystems Biology CSSB Building 15 EMBL Laboratories 02 228 CryoEM facility Basement EMBL Hamburg 48e Building Ground Floor P14 beamline12 00 13 00LunchCentre for StructuralSystems Biology CSSB Building 15 Ground floor13 00 14 00Meet the expert session 2 Biophysical Characterization of Ligand Binding to Membrane Transporter Proteins Dr Nathan Adams Nanotemper GmbH Biomolecular Characterization of membrane proteins with Mass Photometry Dr Sebastian Joecks Refeyn LtdCentre for StructuralSystems Biology CSSB Building 15 Lecture Hall14 00 17 00Parallel practical session 11Practical A2 Transfection of HEK293F cells for recombinant protein expression and analysis of expression of integral membrane proteinsPractical D Reconstitution technologies of membrane proteins liposomes and artificial bilayersPractical E Native mass spectrometry on membrane adaptor proteins complexesPractical I Cryo EM grid preparation data recording and 3D reconstructionPractical H Time resolved serial crystallography of integral membrane proteins in lipidic cubic phaseCentre for StructuralSystems Biology CSSB Building 15 EMBL Laboratories 02 228 CryoEM facility Basement EMBL Hamburg 48e Building Ground Floor P14 beamline17 00 17 30Coffee BreakEMBL Hamburg Building 48e Second Floor Terrace17 30 18 30Wrap up sessionCentre for StructuralSystems Biology CSSB Building 15 Lecture Hall19 00 22 00Farewell barbecue dinner Practical information Registration fees and motivation letter The course is limited to 20 participants For selection purposes please note that your application will not be considered without a letter of motivation Registration Registration fees include admission course materials meals and coffee breaks This EMBO course includes accommodation and transportation to and from the DESY Guest House to the venue Academia 500PhD Student 500Industry 1000 A letter to support your visa application will be issued on request once payment of the registration fee is confirmed We recommend that you book your visa appointment as soon as possible to avoid any delay with your visa application Confirmation and payment The registration fee should be paid only after acceptance to the course The results will be announced approximately 2 3 weeks after the application deadline Motivation letter submission After you have logged in and successfully registered you will receive an email asking you to submit your motivation letter Click on the link provided and enter your motivation letter in the text box provided Alternatively you can submit your motivation letter by clicking on the link on the confirmation page directly after registering Instructions Include your relevant skills experience and qualifications showing why you would be suitable for the course Explain why you would like to attend including what you can contribute and how you think you will benefit from the course Please note The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised For detailed instructions please watch our video on how to submit a course motivation letter Further details For further information about registration and motivation letter submission please refer to the FAQ page Financial assistance Financial assistance Limited financial assistance is provided in the form of registration fee waivers travel grants and childcare grants Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course Travel grant The travel grant will cover the cost of travel airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Course within Europe up to 1000 for participants travelling to an EMBL Course from outside Europe up to 500 for any participant travelling to an EMBO Practical Course up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Practical Course up to 700 for any participant working in Croatia Czech Republic Estonia Greece Hungary Italy Lithuania Luxembourg Poland Slovenia and Turkey travelling to an EMBO Practical Course Registration fees are only covered for EMBO Practical Courses The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant There is the possibility to apply for a childcare grant to offset child care costs incurred by participants speakers trainers and organisers when attending a course Eligible costs include but are not limited to fees for a babysitter or child care facility and travel costs for a caregiver Please note that priority will be given to early stage researchers There is a limited amount of funding available for the childcare grants and funds will be distributed amongst eligible applicants Application You may apply for financial assistance when submitting your motivation letter for courses In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application For the Boehringer Ingelheim Fonds Travel Grant there is a pre application question during the motivation letter submission process and if selected you will be requested to complete a standard form and documentation consisting of your travel expense estimation Selection The scientific organisers will select the recipients of registration fee waivers and travel grants during the motivation letter or abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection for registration fee waivers and travel grants is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Childcare grants will be allocated in the same timeframe 6 8 weeks before the event start date Please note that priority will be given to early stage researchers Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details See our list of external funding opportunities and for further information about financial assistance please refer to the FAQ page Accommodation and transport Reservations for double room accommodation single bed at the Hotel Schmidt Reventlowstra e 60 22605 Hamburg have been made Note accommodation is included in the registration fee There is a direct bus connection to the campus from outside the hotel and it is also right beside the train station Othmarschen Further information Address EMBL Hamburg Notkestra e 85 Buliding 48e 22607 Hamburg GermanyFrom Hamburg airport take line S1 to Othmarschen 18 stops 45 min change to bus number 1 towards Rissen or Schenefelder Holt to Zum H nengrab DESY 5 stops 10 min From Hamburg Altona train station take bus number 1 to Zum H nengrab DESY 15 stops 25 min Ticket costs Public Transport ca 3 60 and a taxi will be around 45 Technical requirements and event software Technical requirements Below you will find the software and technical requirements for this course A laptop with preinstalled software will be provided to each participant Event software The EMBL eCampus learning platform will be used to collaborate communicate and network with all of the course participants All participants will receive information on how to join shortly before the course We recommend using Chrome Safari or Mozilla Firefox browsers for eCampus Sponsors Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other events or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9...

Maria Garcia Alai, Simon Mortensen, Kim Remans, Henning Tidow

EMBO Practical Course

EMBL Hamburg

2 September - 5 September 2024

Imaging mouse development

Edit

September 02, 2024 00:002024ConferenceEMBL Heidelberg, Virtual

Description OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Conference overview This workshop aims to bring together and help establish an emerging community with the common goal of four dimensional reconstruction of mammalian development A number of long standing questions surrounding the early development of mammals have been inaccessible to molecular research due to technical limitations and poor physical accessibility of these processes How is the body plan established in the early embryo How is morphogenesis coordinated with lineage specification The recent revolutions in advanced light microscopy and bioimage informatics have opened up completely new avenues to address these questions and make fundamental advances in our understanding of the developing mammalian embryo The workshop will bring together members of the mouse developmental community advanced microscopy computational image analysis and more broadly quantitative biology to raise awareness about the available techniques and foster a discussion about how we can utilize them to resolve the outstanding questions This will also be an excellent opportunity to have an open conversation about what tools are still needed and how to make large datasets publicly available Session topics Early development Advanced microscopy and analysis Post implantation development Biophysical characterisation and tools Theory and modelling This event has been granted the following EMBO sustainability badge Grade 2 of 3 Speakers Speakers Emma Andersson Karolinska Institutet Sweden Kazuhiro Aoki National Institute for Basic Biology Japan Ripla Arora Michigan State University USA Chii Jou Chan MBI Singapore Singapore Jan Ellenberg EMBL Heidelberg Germany Isabel Espinosa Medina Janelia Research Campus USA Takashi Hiiragi Hubrecht Institute The Netherlands Jean Leon Maitre Institut Curie France Danijela Matic Vignjevic Institut Curie France Kate McDole MRC LMB Cambridge UK Eszter Posfai Princeton University USA Robert Prevedel EMBL Heidelberg Germany Guillaume Salbreux University of Geneva Switzerland Melina Schuh Max Planck Institute for Multidisciplinary Sciences Germany Miquel Sendra Spanish National Center for Cardiovascular Research CNIC Spain James Sharpe EMBL Barcelona Spain Shankar Srinivas University of Oxford UK Hari Shroff Janelia Research Campus USA Ann Sutherland University of Virginia USA C cile Sykes Ecole Normale Sup rieure CNRS France Scientific organisers Jan Ellenberg EMBL Heidelberg Germany Kate McDole MRC LMB Cambridge UK Isabel Espinosa Medina Janelia Research Campus USA Robert Prevedel EMBL Heidelberg Germany Shankar Srinivas University of Oxford UK Conference organiser Julia Patricia Nohle Course and Conference Officer EMBL Heidelberg Germany Programme Are you on social media Post using EMBOMouseDev and don t forget to tag EMBLEvents Please note that the programme is subject to change Some speakers may need to join virtually to give their talk For registered participants recorded talks will be accessible on demand for 2 weeks after the end of the event unless indicated otherwise Day 1 Monday 2 September 2024 Time Europe Berlin Session12 00 13 00Registration and light refreshments13 00 13 15Opening remarks13 15 18 55Session 1 Pre implantation developmentChair Robert Prevedel EMBL Heidelberg Germany13 15 13 40Dissection of zygotic spindle assembly in the mouse embryo using advanced light sheet microscopyJan Ellenberg EMBL Heidelberg Germany available on demand after live stream 13 40 14 05Spatial patterning of mitochondrial energy production in mouse oocytes Yash Rana Harvard University USA available on demand after live stream 14 05 14 30Uncovering temporal regulation mechanisms in mouse diapause Eleonore Ocana Babraham Institute UK available on demand after live stream 14 30 14 55Mechano hydraulic control of mammalian ovarian follicle developmentChii Jou Chan MBI Singapore Singapore available on demand after live stream 14 55 15 30Break and Meet the speakers15 30 15 55New insights into oocyte meiosisMelina Schuh Max Planck Institute for Multidisciplinary Sciences Germany available on demand after live stream 15 55 16 20Exploring nucleocytoplasmic dynamics in mouse preimplantation embryos insights into early developmentManon Lesage Institut Curie France available on demand after live stream 16 20 16 45New insight into genome integrity protection in early mammalian embryos D vid Drutovic Institute of Animal Physiology and Genetics of the Czech Academy of Sciences Czech Reublic available on demand after live stream 16 45 17 15Break and Meet the speakers17 15 17 40A tug of war between germ cell motility and stable intercellular bridges determines cyst size in miceEszter Posfai Princeton University USA available on demand after live stream 17 40 18 05NODAL signaling is required for blastocyst development in the mouse Futura Gattobigio Institut Jacques Monod France available on demand after live stream 18 05 18 55Flash talk session 39 Ioakeim Ampartzidis 40 Mariana Barroso 41 Davide Benvegn 42 Madeleine Chalifoux 44 Yassin Harim 45 Chanchal Thomas Manully 46 Konstantinos Miti 47 Joanna Suszynska Zajczyk 48 Jake Turley 49 Michaela Va kovicov 50 Anoop Vadakan Cherian 51 Ling Wang18 55 20 10Dinner20 10 21 30After dinner drinks and pub quiz Day 2 Tuesday 3 September 2024 Time Europe Berlin Session09 30 12 05Session 2 Advanced microscopy and analysisChair Shankar Srinivas University of Oxford UK09 30 09 55Imaging and dynamic analysis of the post implantation mouse embryoKate McDole MRC LMB Cambridge UK09 55 10 203DMOUSEneST A method using three dimensional label free higher harmonic generation microscopy for evaluation of decidualization efficacy in miceAudrey Savolainen University of Oulu Finland available on demand after live stream 10 20 10 45Advancing optical methods to study mouse development in vivoRobert Prevedel EMBL Heidelberg Germany available on demand after live stream 10 45 11 15Coffee Break and Meet the speakers11 15 11 40Data driven image restorationHari Shroff HHMI Janelia Research Campus USA available on demand after live stream 11 40 12 05Brillouin microscopy for live imaging of mechanical properties in biologyCarlo Bevilacqua EMBL Heidelberg Germany available on demand after live stream 12 05 13 00Lunch and Meet the speakers13 00 18 30Session 3 Early embryogenesisChair Kate McDole MRC LMB Cambridge UK13 00 13 25Illuminating the uterine path from embryo movement to implantationRipla Arora Michigan State University USA available on demand after live stream 13 25 13 50Effects of blastocyst elongation and implantation chamber formation on the alignment of the embryonic axis and uterine axisToshihiko Fujimori National Institute for Basic Biology Japan13 50 14 15Deep tissue spatial omics Imaging whole embryo transcriptomics and subcellular structures at high spatial resolutionZhe Liu HHMI Janelia Research Campus USA available on demand after live stream 14 15 14 40Optimality for developmental robustnessTakashi Hiiragi Hubrecht Institute The Netherlands available on demand after live stream 14 40 15 10Coffee Break and Meet the speakers15 10 15 35Behavioural and mechanical heterogeneities underpin cell migration essential for mouse anterior patterningShankar Srinivas University of Oxford UK available on demand after live stream 15 35 16 00In toto multi tissue analysis using light sheet imaging reveals VE epiblast counter flow during anterior patterningMatthew Stower University of Oxford UK available on demand after live stream 16 00 16 25A place and time to die selective cell death and morphogenesis of the mammalian foregut pocketJenny Kretzschmar MRC Laboratory of Molecular Biology UK16 25 17 00Coffee Break and Meet the speakers17 00 18 30Poster session18 30Free evening Day 3 Wednesday 4 September 2024 Time Europe Berlin Session10 30 13 05Session 4 Advanced toolsChair Robert Prevedel EMBL Heidelberg Germany10 30 10 55TEMPO enables sequential genetic labelling and manipulation of vertebrate cell lineagesIsabel Espinosa Medina HHMI Janelia Research Campus USA10 55 11 20In vivo and ex vivo approaches to study the development of pancreatic innervationJoaquin Lilao Garzon HHMI Janelia Research Campus USA11 20 11 45Mapping embryonic development with ultrasound guided in utero next generation single cell lineage tracingEmma Andersson Karolinska Institutet Sweden available on demand after live stream 11 45 12 15Coffee Break and Meet the speakers12 15 12 40Optogenetics and live cell imaging visualize the dynamic regulation of cell surface tension and cell cell junctionsKazuhiro Aoki National Institute for Basic Biology Japan available on demand after live stream 12 40 13 05Reconstituting mouse embryogenesis ex uteroAlejandro Aguilera Castrejon HHMI Janelia Research Campus USA13 05 13 30C3PO Cell 3D Positioning by Optical encoding and its application to spatial transcriptomicsJames Sharpe EMBL Barcelona Spain available on demand after live stream 13 30 14 30Lunch and Meet the speakers14 30 17 30Session 5 OrganogenesisChair Isabel Espinosa Medina HHMI Janelia Research Campus USA14 30 14 55Live mapping of cardiac specification in gastrulating mouse embryosMiquel Sendra CNIC Spain available on demand after live stream 14 55 15 20Visualising the emergence of patterned calcium oscillations within the developing mammalian heartShifaan Thowfeequ University of Oxford UK available on demand after live stream 15 20 15 45Plasticity of ventricle position after heart looping in heterotaxyAudrey Desgrange Universit Paris Cit Imagine Institut Pasteur France available on demand after live stream 15 45 16 15Coffee break and Meet the speakers16 15 16 40Regulation of cell intercalation in the developing neural tubeAnn Sutherland University of Virginia USA available on demand after live stream 16 40 17 05Imaging isoforms in the developing cerebral cortexInes Gonzalez Aspe Instituto Cajal CSIC Spain available on demand after live stream 17 05 17 30Unexpected differentiation patterns during development and regeneration of hair cells in the inner earDavid Sprinzak Tel Aviv University Israel available on demand after live stream 17 30 17 55Homeostasis of gut epithelium under mechanical stressDanijela Matic Vignjevic Institut Curie France available on demand after live stream 17 55 18 45Pre dinner drinks18 45 19 45Conference dinner in the canteen19 45 22 15Networking Day 4 Thursday 5 September 2024 Time Europe Berlin Session10 00 11 55Session 6 BiomechanicsChair Isabel Espinosa Medina HHMI Janelia Research Campus USA10 00 10 25Active surfaces and biological morphogenesisGuillaume Salbreux University of Geneva Switzerland available on demand after live stream 10 25 10 50Mechanics of blastocyst morphogenesisJean Leon Maitre Institut Curie France available on demand after live stream 10 50 11 15Critical phenomenon associated with luminogenesis during ovarian follicle developmentKim Whye Leong Mechanobiology Institute Singapore available on demand after live stream 11 15 11 40Inferring cell nucleus translocation during squeezed motility of MEF cellsC cile Sykes Institut Curie France available on demand after live stream 11 40 11 55Closing Remarks and Poster Prize Announcements11 55 12 25Packed lunch and departure Practical information Registration fees and abstract submission On site registration fees include admission conference materials meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Virtual registration fees include access to all of the talks livestreamed and on demand and facility to submit questions On site Academia 550On site PhD Student 350On site Industry 750On site Journal Editors 300Virtual Academia 200Virtual PhD Student 150Virtual Industry 275 Editors from scientific journals are allowed to attend at a reduced rate but asked to contribute to the conference in return by taking part in meet the editors sessions or other planned activities within the programme A letter to support your visa application will be issued on request once payment of the registration fee is confirmed We recommend that you book your visa appointment as soon as possible to avoid any delay with your visa application Accredited journalists may be eligible to register for complimentary press registration Registrants may be required to provide accreditation or equivalent proof of press membership after registration Please contact Julia Patricia Nohle for more information Please note that we do not offer complimentary registrations for editors of scientific journals Confirmation and payment Registration will be on a first come first served basis Your place can only be confirmed after payment of the registration fee If you are added to our waiting list please consider taking advantage of our offerings to participate virtually On site participants Types of payments accepted are international bank transfers and credit card payments Virtual participants We are only able to accept card payments In exceptional cases we can accept bank transfers Please contact events embl de for details Abstract submission Only participants registering to attend the on site event are eligible to submit an abstract Abstracts will not be accepted from virtual participants After registration you can submit your abstract via a separate link that will be provided in the email confirmation Alternatively you can access the link on the confirmation page directly after registering The same login credentials are used for both processes Please note Abstract body The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised Title The title should not exceed 20 words Only the first word of the title should start with a capital letter and the rest should be lowercase Authors and affiliations Please fill in the author s details as requested in the online form The compulsory fields are First Name Last Name Organisation Name Affiliation or Company Country and Email Kindly mark only one author in the role of First Author and please don t forget to indicate who will be the Presenter Please enter your co authors correctly via the system by adding accounts together with their organisation institute Do not copy paste them into the body of the abstract text as they will not be indexed in the abstract book Presentation types When submitting your abstract you can apply for an oral or poster presentation A selection process will take place with the results announced 2 3 weeks after the abstract submission deadline For detailed instructions on how to submit a conference abstract follow the instructions provided in this video Please check our FAQs pages for further information on how to submit an abstract Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of registration fee waivers travel grants and childcare grants Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course or conference Travel grant The travel grant will cover the cost of travel to an on site event airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from within Europe up to 1000 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from outside Europe up to 500 for any participant travelling to an EMBO Workshop up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Workshop up to 700 for any participant working in Croatia Czech Republic Estonia Greece Hungary Italy Lithuania Luxembourg Poland Slovenia and Turkey travelling to an EMBO Workshop Registration fees are only covered for EMBO Workshops The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant There is the possibility to apply for a childcare grant to offset child care costs incurred by participants speakers and organisers when attending a conference Eligible costs include but are not limited to fees for a baby sitter or child care facility and travel costs for a caregiver Please note that priority will be given to early stage researchers In order to apply for this grant you must be registered by the abstract submission deadline There is a limited amount of funding available for the childcare grants and funds will be distributed amongst eligible applicants Application On site participants You may apply for financial assistance when submitting your abstract In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Virtual participants If you are attending virtually you can apply for financial assistance in the submission portal by the abstract deadline Read the instructions on how to apply for financial assistance Only submissions for financial assistance will be accepted Presentation abstracts cannot be submitted here and will be declined In your application you will be asked to summarise your current work answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Selection The scientific organisers will select the recipients of registration fee waivers and travel grants during the motivation letter or abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection for registration fee waivers and travel grants is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Childcare grants will be allocated in the same timeframe 6 8 weeks before the event start date Please note that priority will be given to early stage researchers Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details View our list of external funding opportunities and information on attending a conference as an event reporter For further information about financial assistance please refer to the FAQ page Accommodation and shuttles Accommodation is not included in the conference registration fee The hotels below have rooms on hold for participants until 4 weeks before check in date in some cases at special rates Please email the hotel directly quoting the booking code IMD24 01 to confirm the exact price of the room Hotel AnlageHotel ibis HeidelbergPremier Inn Heidelberg CityHotel Bayrischer Hof ISG Hotel Staycity Aparthotel HeidelbergB B HotelLeonardo Hotel Heidelberg City CentreSteffi s Hostel HeidelbergExzellenz HotelMeininger HeidelbergHotel Vier Jahreszeiten HeidelbergHotel Holl nder Hof Hotel MonptiHilton Heidelberg Travel information For travel information please see here If you are travelling to the conference within Germany then you are eligible for the Deutsche Bahn Event Ticket called the Veranstaltungsticket in German This will result in a lower ticket price if your travel distance to Heidelberg is more than 100 km You need to provide proof of your event attendance when purchasing the ticket For more information in English see here or in German see here You can book your ticket here Conference shuttle buses Conference shuttle buses are free of charge for participants and depart from designated bus stops near the hotels to EMBL and back mornings and evenings The bus stops for this conference are Staycity Aparthotel Speyerer Str 7 Kurf rsten Anlage Opposite Main Train Station Premier Inn Kurf rsten Anlage 23 Leonardo Hotel Heidelberg City Center Bergheimer Str 63 Neckarm nzplatz Heidelberg Tourist Information Peterskirche Bus stop Hilton Hotel Kurf rsten Anlage 1 ISG Hotel Im Eichwald 19 Conference shuttle bus schedule View Conference shuttle bus stops and hotels in a larger map Please note that not every bus stop will be used for every event Further details Address EMBL Meyerhofstra e 1 69117 Heidelberg Germany For more information about accommodation and travel please refer to the FAQ page On site information Catering All meals and coffee breaks are included in the registration fee Our catering staff will prepare a wide variety of vegetarian meals meat and fish dishes soups pasta fresh fruit and vegetables as well as a variety of desserts Please wear your badge at all times when serving yourself No food or drinks are allowed in the auditorium Charging lockers There are lockers available next to the stairs leading down into the Auditorium You will find some of those equipped with sockets to charge your smartphone tablet etc Electricity and charging station In most places the electricity is 220 volts AC 50 cycles An adaptor and a plug that fits the German socket may be needed for your appliances laptop i e American Japanese etc A USB charging station for electronic devices is available at the registration desk EMBL merchandise If you are interested in purchasing EMBL merchandise products presented in the glass display in the registration area please email the EMBL shop to place an order or get in contact with your Course Organiser Kindly note the EMBL shop is only open upon request and all purchases must be made in cash Euros only Health and safety notes Please read EMBL s COVID 19 safety policy for on site events Do not smoke in any EMBL building Eating and drinking is prohibited in the Auditorium and all laboratories Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required The first aid room is located next to the ATC Registration Desk room 10 205 Dial the Emergency number 222 from any EMBL internal phone only Where is the accident What happened How many injured Emergency number 06221 387 7821 from mobile phones Please report all accidents to the conference officer at the registration desk In case of fire Press the nearest fire alarm button or the Emergency number 222 from any internal phone A loud fire alarm will go off if an evacuation is required On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting points Do not use the lifts Beyond first aid Please remember to bring your own medication if needed to the conference Note that the next pharmacy is a 4 minute drive from the EMBL but for many medications you will be required to see a doctor to get a prescription Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg In any case the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary Internet Wi Fi is available on campus using the EMBL Events network and the event specific password which will be provided on site The eduroam network secure worldwide roaming access service developed for the international research and education community is also available Lost and found Lost and Found items are kept at the registration desk until the end of the conference Luggage There are lockers available on site to store your luggage which require a 2 EURO coin to operate There is another luggage room on level E0 which is free to use but remains unlocked during the conference Nursing room There is a nursing room available in the ATC Rooftop Lounge on level A29 Photography During the conference an EMBL Photographer may be taking photos If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Printing We can help to print your boarding pass train ticket Please send it to events embl de and collect your print outs at the registration desk Room for prayer yoga and meditation There is a room for prayer meditation and yoga located on level E0 behind the Auditorium Please be respectful of others using the room Sightseeing A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing Travel to and from the venue During the event we provide conference shuttle buses to and from EMBL In addition there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time Information on the conference shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page Useful German expressions HelloHalloGoodbyeAuf Wiedersehen formal Tsch ss informal Good morningGuten MorgenGood afternoonGuten TagGood eveningGuten AbendGood nightGute NachtI m sorryEs tut mir leidExcuse me Entschuldigen SieHow are you Wie gehts I m fine thanks And you Mir geht es gut danke Und Dir Ihnen What is your nameWie hei en Sie formal Wie hei t Du informal My name isIch hei e Do you speak EnglishSprechen Sie englisch I don t understandIch verstehe nichtPlease speak more slowlyK nnen Sie bitte langsamer sprechenThank youDankesch nWhere is the toilet Wo ist die Toilette Please call me a taxiBitte rufen Sie mir ein TaxiHow do I get to Wie komme ich zum zur A beer two beers pleaseEin Bier zwei Bier bitteA glass of red white wine pleaseEin Glas Rot Weisswein bitteThe menu pleaseDie Speisekarte bitteIs there a local speciality Gibt es eine Spezialit t aus dieser Gegend I m vegetarianIch bin VegetarierIt was deliciousEs war hervorragendThe bill pleaseDie Rechnung bitteI have a headacheIch habe KopfschmerzenI have a sore throatIch habe HalsschmerzenMy stomach hurtsIch habe MagenschmerzenI m allergic toIch bin allergisch gegenI need a doctor who speaks EnglishIch brauche einen Arzt der englisch spricht Virtual participation What s included Access to all the livestreamed talks Video library of the recorded talks during the event and for two weeks afterwards Please note at the request of individual speakers some talks are not recorded Facility to submit questions Please note that only on site participants are able to submit abstracts and participate in the poster sessions Event platform We are using an event platform for this conference More information about the platform will be shared ahead of the conference Guidelines Do not broadcast the conference to unregistered participants You are encouraged to tweet and post about the event Tweet unless the speaker specifically says otherwise but be mindful of unpublished data Please do not capture transmit or redistribute data presented at the meeting Additional information can be found in our Code of Conduct Health and well being It is important to stay healthy and move around especially when you are attending an event virtually We have put together a few coffee break stretches and yoga videos in the conference platform for you to enjoy during the event How to ask questions Please use the Q A function in the event platform If you have any other questions you can go to the Help Desk in the event platform Click on more on the top menu and click Help Desk Time zone The programme is planned based on the Europe Berlin time zone unless otherwise stated Please take your time zone into consideration when planning your attendance Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for participants page COVID 19 related questions COVID 19 information for on site events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Event sponsor Bruker Event supporter Media partners EMBO Reports an EMBO Press journal Development The Company of Biologists journal International Union of Biochemistry and Molecular Biology Imaging and Microscopy a Wiley magazine Medinformatics a Bon View Publishing journal Open Biology a Royal Society journal Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information on sponsoring possibilities If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9 Leaderboard 729 90...

Jan Ellenberg, Kate McDole, Isabel Espinosa Medina, Robert Prevedel, Shankar Srinivas

EMBO Workshop

EMBL Heidelberg, Virtual

1 September - 6 September 2024

Genome engineering: CRISPR/Cas in cells and mice

Edit

September 01, 2024 00:002024CourseEMBL Heidelberg

Description OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview Course overview This course will provide training in genome editing and cell engineering in mammalian cells and mouse embryos using the highly efficient CRISPR Cas9 system Participants will learn design of CRISPR targets using bioinformatics tools generation of gene knock outs knock ins and target validation using the most current technologies The course will be split into two groups mammalian cells OR mice based on participants expertise Please note that all participants are expected to engage in all sessions Participants should plan for approximately 1 hour extra per day for self paced learning modules Audience This course is aimed at researchers who are familiar with basic molecular and cell biology techniques and who want to learn how to create an engineered mammalian cell line or mouse model using the most recent and advanced CRISPR Cas9 system No previous experience in genome editing is required Modules resources How to create a CRISPR Cas9 experiment using various design tools Transfection optimisation for efficient gene editing Generation of knock out and knock in cell lines and mouse embryos Validation of genome edited cell lines and embryos Learning outcomes After this course you should be able to Design a CRISPR based project using editing tools for your target gene of interest Choose the right format of gene editing tool and delivery strategy for your cell type or embryos Edit screen and validate the engineered models embryo manipulation What past participants say about the course The EMBL course about CRISPR applications for genome engineering was an incredible experience From the quality of the lectures the availability of the invited speakers to respond to all questions and doubts the openness and diversity of participants to the great organization and the impressive facilities and core facility teams working there It all created a perfect atmosphere for learning about this groundbreaking technique and the inspiring work being done with it as well as great networking I highly recommend this course Sofia Morazzo International Clinical Research Center Czech Republic The course covers all you need to organise your CRISPR experiments in great detail The speakers are fantastic and eager to help with your specific questions The organisation is also fantastic where you only have to think on CRISPR and nothing else Sergio G San Miguel Max Planck Institute for Infection Biology Germany Please see EMBL s COVID 19 safety policy for testing and other requirements to attend this on site course Speakers Speakers Antony Adamson University of Manchester United Kingdom Michela Ascolani EMBL Rome Italy Dana Carroll University of Utah School of Medicine USA Adrianna Castillo EMBL Rome Italy Silke Deckert Thermo Fisher Scientific Germany IDT Technologies Germany Neil Humphreys EMBL Rome Italy Manuel Kaulich Frankfurt University Hospital Germany Kristof Kersse Thermo Fisher Scientific Germany Birgit Koch Max Planck Institute for Medical Research Germany Frank Montoya EMBL Heidelberg Germany Beate Neumann EMBL Heidelberg Germany Alexandre Paix Max Planck Institute for Biology T bingen Germany Karl Petri Universit tsklinikum W rzburg Germany Ian Pringle Thermo Fisher Scientific United Kingdom Kim Remans EMBL Heidelberg Germany Isabel Rollan EMBL Heidelberg Germany Daniel Schraivogel EMBL Heidelberg Germany Maj Simonsen Jackson EMBL Rome Italy Emmanouela Soura Thermo Fisher Scientific United Kingdom Sandra Stobrawa Biozol Calibre Scientific Germany Scientific Organisers Neil Humphreys EMBL Rome Italy Kristof Kersse Thermo Fisher Scientific Germany Birgit Koch Max Planck Institute for Medical Research Germany Elisabeth Zielonka EMBL Heidelberg Germany Course Organisers Charlotte Courtney Course and Conference Officer EMBL Heidelberg Germany Swetlana Krez Training Laboratory Officer EMBL Heidelberg Germany Programme Are you on social media Post using EMBLCRISPRcas and don t forget to tag EMBLEvents Some pre course work such as watching pre recordings protocol reading and computational exercises with estimated time 0 10 hours will be required and will be shared in advance of the course Some speakers may need to join virtually to give their lecture or Q A and the programme is subject to change Day 1 Sunday 1 September 2024 Time Europe Berlin SessionLocation16 00 16 30WelcomeEMBL housenotes and course overviewISG Hotel16 30 18 00Icebreaker Flash talks 2 slides 2 minutes each participant ISG Hotel18 00 19 00 Virtual speaker Live Keynote Lecture Introduction to CRISPR Cas 9 Dana Carroll University of Utah School of Medicine USAISG Hotel19 00Dinner and Networking at ISG HotelISG Hotel Day 2 Monday 2 September 2024 Time Europe Berlin SessionLocation08 30 08 45Bus from ISG Hotel to EMBL08 45 09 00Arrival and coffeeCourtyard Room9 00 9 15Lab Safety Swetlana KrezCourtyard Room09 15 10 15Lecture Purification of Cas9 proteinKim Remans EMBL Heidelberg GermanyCourtyard Room10 15 11 15Lecture CRISPR Cas genome editing to generate transgenic miceNeil Humphreys EMBL Rome ItalyCourtyard Room11 15 11 45Coffee breakCourtyard Room11 45 12 45Everyone Practical 1 gRNA design manual approach Kristof Kersse Thermo Fisher Scientific GermanyCourtyard Room12 45 13 45LunchEMBL Canteen13 45 16 00Everyone Practical 1 gRNA design Basics Benchling Birgit Koch Max Planck Institute for Medical Research GermanyCourtyard Room16 00 16 30Coffee breakCourtyard Room16 30 17 15Mammalian Cell Group Practical 1 1 TrueTag Donor Template Synthesis PCREmmanouela Soura Thermo Fisher Scientific UK Ian Pringle Thermo Fisher Scientific UKTraining Lab A16 30 17 15Short seminar on embryo transfer and demonstrationNeil Humphreys EMBL Rome ItalyMichela Ascolani EMBL Rome ItalyMaj Simonsen Jackson EMBL Rome ItalyIsabel Rollan EMBL Heidelberg GermanyFrank Diego Montoya Castillo EMBL Heidelberg GermanyTraining Lab B17 15 18 30CRISPR Cas in different organismsTips pitfalls and trouble shootingAlexandre Paix Max Planck Institute for Biology T bingen GermanyCourtyard Room18 30 19 30Dinner EMBL Canteen19 30 20 30Practical 1 2 Mammalian Cell Group TrueTag Donor Template Synthesis Gel analysis and Clean upEmmanouela Soura Thermo Fisher Scientific UKIan Pringle Thermo Fisher Scientific UKTraining Lab A19 30 20 30Glass transfer pipet prep harvest embryos Intro to TLR2 system describe injection mix prepNeil Humphreys EMBL Rome ItalyMichela Ascolani EMBL Rome ItalyMaj Simonsen Jackson EMBL Rome ItalyIsabel Rollan EMBL Heidelberg GermanyFrank Diego Montoya Castillo EMBL Heidelberg GermanyTraining Lab B20 30Bus from EMBL to ISG Hotel Day 3 Tuesday 3 September 2024 Time Europe Berlin SessionLocation08 30 08 45Bus from ISG Hotel to EMBL08 45 08 55Arrival and coffeeCourtyard Room08 55 09 00Overview of the dayCourtyard Room9 00 10 00Lecture A rationale for efficient genome editing using linear repair donorsAlexandre Paix Max Planck Institute for Biology T bingen GermanyCourtyard Room10 00 11 00Practical lecture Generation and validation of endogenously tagged cell lineBirgit Koch Max Planck Institute for Medical Research GermanyCourtyard Room10 00 11 00Practical AAV infectionMaj Simonsen Jackson EMBL Rome Italy Michela Ascolani EMBL Rome Italy Neil Humphreys EMBL Rome ItalyTraining Lab B11 00 12 45Practical Group A Transfection of endogenously tagged cell line duplex formation formation of RNP and transfection with CRISPR Birgit Koch Max Planck Institute for Medical Research Germany Group B True Design Tool and example exercises Kristof Kersse Thermo Fisher Scientific GermanyCell culture11 00 12 45Practical 1 2 1st Microinjection electroporationElectroporation Maj Simonsen Jackson EMBL Rome ItalyMichela Ascolani EMBL Rome ItalyMicroinjection Neil Humphreys EMBL Rome ItalyIsabel Rollan EMBL Heidelberg GermanyFrank Diego Montoya Castillo EMBL Heidelberg GermanySandra Stobrawa Biozol Calibre ScientificTraining Lab BLAR12 45 13 45LunchEMBL Canteen13 45 15 30Practical Group A True Design Tool and example exercisesKristof Kersse Thermo Fisher Scientific GermanyGroup B Transfection of endogenously tagged cell line duplex formation formation of RNP and transfection with CRISPRBirgit Koch Max Planck Institute for Medical Research GermanyCourtyard Room Cell culture13 45 15 30Mouse Embryo Group 2nd Microinjection electroporation and AAVElectroporation Maj Simonsen Jackson EMBL Rome ItalyMichela Ascolani EMBL Rome ItalyMicroinjection Neil Humphreys EMBL Rome ItalyIsabel Rollan EMBL Heidelberg GermanyFrank Diego Montoya Castillo EMBL Heidelberg GermanySandra Stobrawa Biozol Calibre ScientificTraining Lab BLAR15 30 16 00Coffee breakCourtyard Room16 00 18 00Practical 2 3 Mammalian Cell GroupGroup A gRNA efficiency Lipid transfection of 293FT cells with gRNA and Cas9 protein Lipid transfection of 293FT eBFP cells with gRNA Cas9 protein and ssODNEmmanouela Soura Thermo Fisher Scientific UKIan Pringle Thermo Fisher Scientific UKGroup B gRNA taskBirgit Koch Max Planck Institute for Medical Research GermanyKristof Kersse Thermo Fisher Scientific GermanyCourtyard Room Cell culture16 00 18 00Mouse Embryo Group 3rd Microinjection electroporation and AAVElectroporation Maj Simonsen Jackson EMBL Rome ItalyMichela Ascolani EMBL Rome ItalyMicroinjection Neil Humphreys EMBL Rome ItalyIsabel Rollan EMBL Heidelberg GermanyFrank Diego Montoya Castillo EMBL Heidelberg GermanySandra Stobrawa Biozol Calibre ScientificTraining Lab BLAR18 00 19 00Dinner EMBL Canteen19 00 20 30Practical Group A gRNA taskBirgit Koch Max Planck Institute for Medical Research GermanyKristof Kersse Thermo Fisher Scientific GermanyGroup B gRNA efficiency Lipid transfection of 293FT cells with gRNA and Cas9 protein Lipid transfection of 293FT eBFP cells with gRNA Cas9 protein and ssODNEmmanouela Soura Thermo Fisher Scientific UKIan Pringle Thermo Fisher Scientific UKCell culture19 00 20 30Practical 2 3Mouse Embryo GroupExtra time with Embryos microinjection and embryos transfer KSOM mediaO N culture Student lead requests for extra training All trainersTraining Lab B20 30Bus from EMBL to ISG Hotel Day 4 Wednesday 4 September 2024 Time Europe Berlin SessionLocation08 30 08 45Bus from ISG Hotel to EMBL08 45 08 55Arrival and coffeeCourtyard Room08 55 09 00Overview of the dayCourtyard Room09 00 10 00Lecture Gene editing in different experimental modelsAntony Adamson The University of Manchester UKCourtyard Room10 00 11 00Practical Harvest cells and prepare for FACS analysisBirgit Koch Max Planck Institute for Medical Research GermanyCell culture10 00 11 00Practical 4 Assess and clean up 2 cell microinjected embryosMaj Simonsen Jackson EMBL Rome ItalyIsabel Rollan EMBL Heidelberg GermanyFrank Diego Montoya Castillo EMBL Heidelberg GermanyTraining Lab B11 00 11 30Coffee breakCourtyard Room11 30 12 30Lecture Safety validating and improving CRISPR 2 0 to enhance immune cell therapiesKarl Petri Universit tsklinikum W rzburg GermanyCourtyard Room12 30 13 30LunchEMBL Canteen13 45 15 45Practical 1 3 4 Mammalian Cell Group Group A Tag Knock in Electroporation of 293FT with gRNA Cas9 protein and TrueTag donor templateEmmanouela Soura Thermo Fisher Scientific UKIan Pringle Thermo Fisher Scientific UKGroup B Project discussionBirgit Koch Max Planck Institute for Medical Research GermanyKristoff Kersse Thermo Fisher Scientific GermanyCourtyard Room Cell culture13 45 15 45Practical 4 Mouse Embryo Group Thaw pre prepared blastocysts assess viability extract DNA Design and set up cut test PCR Prepare agarose gelNeil Humphreys EMBL Rome ItalyMichela Ascolani EMBL Rome ItalyMaj Simonsen Jackson EMBL Rome ItalyIsabel Rollan EMBL HeidelbergTraining Lab B15 45 16 15Coffee break16 15 18 15Practical 1 3 4 Mammalian Cell Group Group A Project discussionBirgit Koch Max Planck Institute for Medical Research GermanyKristof Kersse Thermo Fisher Scientific GermanyGroup B Tag Knock in Electroporation of 293FT with gRNA Cas9 protein and TrueTag donor templateEmmanouela Soura Thermo Fisher Scientific UKIan Pringle Thermo Fisher Scientific UKCourtyard Room Cell culture16 15 18 15Practical 5 Mouse Embryo Group Set up T7 assay and mutant specific PCRs Run O N project discussion Neil Humphreys EMBL Rome ItalyMichela Ascolani EMBL Rome ItalyMaj Simonsen Jackson EMBL Rome ItalyTraining Lab B18 15 20 30Pizza Dinner andDiscussion round and drinks Ethical issues of CRISPR technology and genome engineeringLead Antony Adamson The University of Manchester UKATC Rooftop lounge20 30Bus to ISG Hotel Day 5 Thursday 5 September 2024 Time Europe Berlin SessionLocation08 30 08 45Bus from ISG Hotel to EMBL08 45 08 55Arrival and coffeeCourtyard Room08 55 09 00Overview of the dayCourtyard Room09 00 10 00Lecture Imaged based high throughput screening RNAi vs CRISPRBeate Neumann EMBL Heidelberg GermanyCourtyard Room10 00 11 45Practical in Groups Practicals 5 1 5 2 Mammalian Cell Group GCD Cell Harvest and lysis set up GCD PCREmmanouela Soura Thermo Fisher Scientific UKIan Pringle Thermo Fisher Scientific UKCell culture Training Lab A10 00 11 45Mouse Embryo Group Practicals 5 1 5 2Assess and clean up 4 to 8 cell embryos Run Gels for PCRs Analyze results Cut out gel and submit for Sanger sequencingNeil Humphreys EMBL Rome ItalyMichela Ascolani EMBL Rome ItalyMaj Simonsen Jackson EMBL Rome ItalyIsabel Rollan EMBL Heidelberg GermanyTraining Lab B11 45 12 15Group PhotoTBC12 15 13 15LunchEMBL Canteen13 15 14 15Lecture The 3Cs technology for CRISPR gRNA library generationManuel Kaulich Goethe University GermanyCourtyard Room14 15 16 30Practical in Groups Practical 5 3 Mammalian Cell Group PCR analysis set up GCD re annealing reactionPractical 5 4 5 5Set up digestion for GCD gel purification sample submission for sanger sequencingGel analysis of GCDEmmanouela Soura Thermo Fisher Scientific UKIan Pringle Thermo Fisher Scientific UKTraining Lab A14 15 16 30Mouse Embryo Group Project discussion focus on the analysis of sequencing data and design optionsNeil Humphreys EMBL Rome ItalyMichela Ascolani EMBL Rome ItalyIsabel Rollan EMBL Heidelberg GermanyAntony Adamson The University of Manchester UKTraining Lab B16 30 17 00Coffee breakCourtyard Room17 00 18 00Lecture Pooled genome wide CRISPR screens in single cellsDaniel Schraivogel EMBL Heidelberg GermanyCourtyard Room18 15Bus departure to ISG Hotel19 00Bus from ISG Hotel to Dinner downtown19 30Downtown dinnerZum Roten Ochsen Day 6 Friday 6 September 2024 Time Europe Berlin SessionLocation08 30 08 45Bus from ISG Hotel to EMBLCourtyard Room08 45 08 55Arrival and coffeeCourtyard Room08 55 09 00Overview of the dayCourtyard Room9 00 10 30Technology Lounge Genome modification technologiesPresentation by different companiesThermo Fisher ScientificNew England Biolabs Karl von Laer Integrated DNA Technologies Marc Bleischwitz and K Julia Duda Courtyard Room10 30 12 30Practical in Groups Mammalian Cell Group Group A Examine BFP cells and TrueTag Knock in via microscopy and FACSEmmanouela Soura Thermo Fisher Scientific UKIan Pringle Thermo Fisher Scientific UKGroup B Knock In cell validation DNA Preparation and set up of PCR at the end of sessionBirgit Koch Max Planck Institute for Medical Research GermanyChange Groups after 60 minwith concurrent coffee breakTraining Lab A10 30 11 30Mouse Embryo Group Thaw TLR2 embryos and examine KO and KI morular blastocysts for florescence Knock In validation Neil Humphreys EMBL Rome ItalyMichela Ascolani EMBL Rome ItalyMaj Simonsen Jackson EMBL Rome ItalyIsabel Rollan EMBL Heidelberg GermanyTraining Lab B11 30 12 305 participants Image embryos ALMF 5 participants Project discussionNeil Humphreys EMBL Rome ItalyMichela Ascolani EMBL Rome ItalyMaj Simonsen Jackson EMBL Rome ItalyIsabel Rollan EMBL Heidelberg GermanyBeate Neumann EMBL Heidelberg GermanyALMFCourtyard Room12 30 13 30LunchEMBL Canteen13 30 15 45Mammalian Cell Group Knock In cell validation Gel gel analysisBirgit Koch Max Planck Institute for Medical Research Germanywith IC tour or other tour Training Lab A13 30 14 305 participants Image embryos ALMF 5 participants Project discussionNeil Humphreys EMBL Rome ItalyMichela Ascolani EMBL Rome ItalyMaj Simonsen Jackson EMBL Rome ItalyIsabel Rollan EMBL Heidelberg GermanyBeate Neumann EMBL Heidelberg GermanyALMFCourtyard Room14 30 15 45Mouse embryo group Tour of LAR FacilityErnesto de la Cueva Bueno EMBL HeidelbergLAR15 45 16 15Solutions room and final wordsCourtyard Room16 30Bus shuttle downtown and central station Practical information Registration fees and motivation letter The course is limited to 20 participants For selection purposes please note that your application will not be considered without a letter of motivation Registration Registration fees include admission course materials meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Academia 815PhD Student 815Industry 1325 A letter to support your visa application will be issued on request once payment of the registration fee is confirmed We recommend that you book your visa appointment as soon as possible to avoid any delay with your visa application Confirmation and payment The registration fee should be paid only after acceptance to the course The results will be announced approximately 2 3 weeks after the application deadline Motivation letter submission After you have logged in and successfully registered you will receive an email asking you to submit your motivation letter Click on the link provided and enter your motivation letter in the text box provided Alternatively you can submit your motivation letter by clicking on the link on the confirmation page directly after registering Instructions Include your relevant skills experience and qualifications showing why you would be suitable for the course Explain why you would like to attend including what you can contribute and how you think you will benefit from the course Please note The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised For detailed instructions please watch our video on how to submit a course motivation letter Further details For further information about registration and motivation letter submission please refer to the FAQ page Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of registration fee waivers travel grants and childcare grants Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course Travel grant The travel grant will cover the cost of travel airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Course within Europe up to 1000 for participants travelling to an EMBL Course from outside Europe up to 500 for any participant travelling to an EMBO Practical Course up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Practical Course up to 700 for any participant working in Croatia Czech Republic Estonia Greece Hungary Italy Lithuania Luxembourg Poland Slovenia and Turkey travelling to an EMBO Practical Course Registration fees are only covered for EMBO Practical Courses The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant There is the possibility to apply for a childcare grant to offset child care costs incurred by participants speakers trainers and organisers when attending a course Eligible costs include but are not limited to fees for a babysitter or child care facility and travel costs for a caregiver Please note that priority will be given to early stage researchers There is a limited amount of funding available for the childcare grants and funds will be distributed amongst eligible applicants Boehringer Ingelheim Fonds travel grant Applies to selected courses only Availability will be indicated during the motivation letter submission process This grant covers costs related to your attendance at the course registration travel and accommodation costs The grant is restricted to PhD students and postdocs who conduct basic biomedical research Whether you are eligible to apply for a travel grant depends on when you received your university entrance qualification e g Abitur A Levels High School Diploma Final State Examination for PhD and MD students as well as graduates the university entrance qualification must not have been obtained more than 11 years ago at the time of the envisaged course for postdocs the university entrance qualification must not have been obtained more than 13 years ago at the time of the envisaged course Application You may apply for financial assistance when submitting your motivation letter for courses In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application For the Boehringer Ingelheim Fonds Travel Grant there is a pre application question during the motivation letter submission process and if selected you will be requested to complete a standard form and documentation consisting of your travel expense estimation Selection The scientific organisers will select the recipients of registration fee waivers and travel grants during the motivation letter or abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection for registration fee waivers and travel grants is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Childcare grants will be allocated in the same timeframe 6 8 weeks before the event start date Please note that priority will be given to early stage researchers Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details See our list of external funding opportunities and for further information about financial assistance please refer to the FAQ page Accommodation and travel Hotel Accommodation is not included in the registration fee Participants are expected to book and pay for their own accommodation A mix of single and twin rooms have been reserved for 6 nights from Saturday 31 August 2024 Friday 6 September 2024 at the ISG Hotel Single rooms are limited and will be available on a first come first served basis After the selection process selected participants should contact the hotel directly to make a booking with a booking code code of your course e g GEE24 01 by the deadline of Monday 5 August 2024 We recommend that all course participants stay in the dedicated hotel for the course Travel information For travel information please see here If you are travelling to the conference within Germany then you are eligible for the Deutsche Bahn Event Ticket called the Veranstaltungsticket in German This will result in a lower ticket price if your travel distance to Heidelberg is more than 100 km You need to provide proof of your event attendance when purchasing the ticket For more information in English see here or in German see here You can book your ticket here Local transport Shuttle buses will go from the ISG Hotel to EMBL and back mornings and evenings A bus schedule and location of the bus stops will be made available prior to the meeting Further details Address EMBL Heidelberg Meyerhofstra e 1 69117 Heidelberg GermanyFor more information about accommodation and travel please refer to the FAQ page On site information Catering All meals and coffee breaks are included in the registration fee Our catering staff will prepare a wide variety of vegetarian meals meat and fish dishes soups pasta fresh fruit and vegetables as well as a variety of desserts Please wear your badge at all times when serving yourself No food or drinks are allowed in the laboratories Electricity and charging station In most places the electricity is 220 volts AC 50 cycles An adaptor and a plug that fits the German socket may be needed for your appliances laptop i e American Japanese etc A USB charging station for electronic devices is available at the registration desk EMBL Merchandise If you are interested in purchasing EMBL merchandise products presented in the glass display in the registration area please email the EMBL shop to place an order or get in contact with your Course Organiser Kindly note the EMBL shop is only open upon request and all purchases must be made in cash Euros only Health and safety notes Please read EMBL s COVID 19 safety policy for on site events Do not smoke in any EMBL building Eating and drinking is prohibited in all laboratories Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required The first aid room is located next to the ATC Registration Desk room 10 205 Dial the Emergency number 222 from any EMBL internal phone only Where is the accident What happened How many injured Emergency number 06221 387 7821 from mobile phones Please report all accidents to the conference officer at the registration desk In case of fire Press the nearest fire alarm button or the Emergency number 222 from any internal phone A loud fire alarm will go off if an evacuation is required On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting points Do not use the lifts Beyond first aid Please remember to bring your own medication if needed to the conference Note that the next pharmacy is a 4 minute drive from the EMBL but for many medications you will be required to see a doctor to get a prescription Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg In any case the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary Internet Wi Fi is available on campus Log in using the EMBL Events network and the event specific password which will be provided on site The eduroam network secure worldwide roaming access service developed for the international research and education community is also available Lost and found Lost and Found items are kept at the registration desk until the end of the conference Luggage There are lockers available on site to store your luggage which require a 2 EURO coin to operate There is another luggage room on level E0 which is free to use but remains unlocked during the conference Nursing room There is a nursing room available in the ATC Rooftop Lounge on level A29 Photography During the conference an EMBL Photographer may be taking photos If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Printing We can help to print your boarding pass train ticket Please send it to events embl de and collect your print outs at the registration desk Room for prayer yoga and meditation There is a room for prayer meditation and yoga located on level E0 behind the Auditorium Please be respectful of others using the room Sightseeing A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing Travel to and from the venue During the event we provide conference shuttle buses to and from EMBL In addition there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time Information on the shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page Map to walk from ISG Hotel to EMBL Additional information Address EMBL Heidelberg Meyerhofstra e 1 69117 Heidelberg Germany ATC orientation map Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page Event software Event software The EMBL eCampus learning platform will be used to collaborate communicate and network with all of the course participants All participants will receive information on how to join shortly before the course We recommend using Chrome Safari or Mozilla Firefox browsers for eCampus Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page COVID 19 related questions COVID 19 information for on site events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Event Partner Event Sponsor Event supporter Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other events or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9...

Neil Humphreys, Kristof Kersse, Birgit Koch, Elisabeth Zielonka

EMBL Course

EMBL Heidelberg

1 September - 10 September 2024

Current methods in cell biology

Edit

September 01, 2024 00:002024CourseEMBL Heidelberg

Description OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview Course overview In the past decade cell biology has undergone transformational changes resulting from improvements in single molecule imaging technologies and in situ structural biology At the same time the emergence of deep learning approaches that have revolutionised the field of image analysis together with techniques that complement imaging approaches to e g dissect the mechanical properties of cells have provided a wealth of quantitative high dimensional data for cell biologists The wealth of data available to cell biologists also comes with new challenges in data handling data analysis and data interpretation To allow researchers to design appropriate experiments and translate the data into meaningful knowledge requires insight into which techniques are best suited to address a specific question which techniques can or must be combined and how the output is best analysed and interpreted The Current methods in cell biology course aims to expose researchers with different backgrounds to the diverse cutting edge methods developed for cell biology to showcase how integrated approaches can address the current big questions in cell biology By attracting a diverse group of participants and exposing them to the recent advances in cell biology the course will equip the participants with the tools to further advance the field The practical sessions will take place in parallel and groups will rotate Participants must select 3 topics out of 11 for practicals 1 3 and 2 topics out of 3 for practicals 4 5 Audience The course will be targeted primarily for postdocs and advanced graduate students who have developed an interest in cell biology We aim to attract a diverse group of scientists who want to expand their expertise by acquiring cutting edge quantitative cell biological biophysical and computational methods to address current problems in cell biology We aim to balance the number of participants with a background in biology and participants coming from other disciplines A key criterion for selection is the potential benefit of adding novel cell biological methods to the participant s own research plans Preference will be given to applicants where there is little or no possibility that the applicant can acquire these technologies at their home institution What past participants say about the course This course has changed my perspective in many aspects of cell biology and allowed me to rethink how to perform crucial experiments The interaction with other participants and the speakers has been without a doubt the best providing an excellent platform for networking during the 10 days of the course Highly recommended in the next editions Anchel de Jaime Soguero COS Heidelberg Germany A wonderful way to learn about and be inspired by new advances in cell biology research The enthusiasm of those teaching made the course stand out as a unique opportunity Victoria Hart University of Sheffield UK This course is kindly supported by the Cell Biology and Biophysics Unit of EMBL Please see EMBL s COVID 19 safety recommendations for testing and other requirements to attend this on site course This event has been granted the following EMBO sustainability badge Grade 1 of 3 Speakers Speakers trainers and staff Niccol Banterle EMBL Heidelberg Germany Florian Berger Utrecht University The Netherlands Beth Cimini Broad Institute USA Sara Cuylen H ring EMBL Heidelberg Germany Claire Deo EMBL Heidelberg Germany Gautam Dey EMBL Heidelberg Germany Alba Diz Mu oz EMBL Heidelberg Germany Jan Ellenberg EMBL Heidelberg Germany Anna Erzberger EMBL Heidelberg Germany Keisuke Goda Goda Lab Tokyo Japan Ralf Jungmann Max Planck Institute of Biochemistry Germany Simone Koehler EMBL Heildeberg Germany Anna Kreshuk EMBL Heidelberg Germany Kate McDole MRC Laboratory of Molecular Biology United Kingdom Rainer Pepperkok EMBL Heidelberg Germany Robert Prevedel EMBL Heidelberg Germany Thomas Quail EMBL Heidelberg Germany Jonas Ries Max Perutz labs Austria Yannick Schwab EMBL Heidelberg Germany Yi Sun EMBL Heidelberg Germany Alejandro Torres S nchez EMBL Barcelona Spain Virtual speaker Fiona Watt EMBL Heidelberg Germany Timo Zimmermann EMBL Heidelberg Germany Trainers LabPeopleBanterle GroupEnrico Salvatore Atorino EMBL Heidelberg GermanyAnna Lippert EMBL Heidelberg GermanyCuylen GroupBanafsheh Golchoubian EMBL Heidelberg GermanyYuki Hayashi EMBL Heidelberg GermanyDey GroupMargarida Araujo EMBL Heidelberg GermanyFelix Mikus EMBL Heidelberg GermanyHiral Shah EMBL Heidelberg GermanyDiz Mu oz GroupSrishti Dar EMBL Heidelberg GermanyLinda Decker EMBL Heidelberg GermanyFilipe Nunes Vicente EMBL Heidelberg GermanyEva Pillai EMBL Heidelberg GermanyRuben Tesoro Moreno EMBL Heidelberg GermanyEllenberg GroupHairuo Dang EMBL Heidelberg GermanyMarina Makharova EMBL Heidelberg GermanyKoki Watanabe EMBL Heidelberg GermanyErzberger GroupRoman Belousov EMBL Heidelberg GermanyJenna Elliott EMBL Heidelberg GermanyK hler GroupCristina Pineiro Lopez EMBL Heidelberg GermanyKreshuk GroupBenedikt Best EMBL Heidelberg GermanyDominik Kutra EMBL Heidelberg GermanyPepperkok TeamGeorge Galea EMBL Heidelberg GermanyMuzamil Majid Khan EMBL Heidelberg GermanyPrevedel GroupLing Wang EMBL Heidelberg GermanyQuail GroupShilpi Dhar EMBL Heidelberg GermanyNethaji Kuruppu EMBL Heidelberg GermanyNatalia Lopez EMBL Heidelberg GermanyJuliette Sebellin EMBL Heidelberg GermanySchwab TeamChandni Bhickta EMBL Heidelberg GermanyIn s Romero Brey EMBL Heidelberg GermanyWatt GroupAdil Boolani EMBL Heidelberg GermanyMirsana Ebrahim EMBL Heidelberg GermanyPurna Gadre EMBL Heidelberg GermanyPavlina Markova EMBL Heidelberg GermanyZimmermann TeamDietrich Walsh EMBL Heidelberg Germany Scientific organisers Niccol Banterle EMBL Heidelberg Germany Beth Cimini Broad Institute USA Simone Koehler EMBL Heidelberg Germany Course organisers Catherine Casas Saavedra Course and Conference Officer EMBL Heidelberg Germany Irena Provaznikova Scientific Training Manager EMBL Heidelberg Germany Programme Are you on social media Post using EMBOCellBiology and don t forget to tag EMBLEvents Some pre course work such as watching pre recordings protocol reading and computational exercises with estimated time 0 10 hours will be required and will be shared in advance of the course Some speakers may need to join virtually to give their lecture or Q A and the programme is subject to change Day 1 Sunday 1 September 2024 Time Europe Berlin SessionLocation15 30 16 00Registration and WelcomeISG Hotel16 00 16 30Welcome Safety introductionISG Hotel16 30 18 00Flash TalksISG Hotel18 00 18 45Challenges and ExpectationsISG Hotel18 45 19 00BreakISG Hotel19 00 20 00DinnerISG Hotel20 00 22 00Networking with DrinksISG Hotel Day 2 Monday 2 September 2024 Time Europe Berlin SessionLocation08 40 08 55Bus from ISG hotel to EMBL Bus Stop08 55 09 00Overview of the daySeminar room 20209 00 09 45Lecture Microscopy basicsRobert Prevedel EMBL Heidelberg GermanySeminar room 20209 45 10 15Break10 15 11 00Lecture Single molecule localization microscopy and MinfluxJonas Ries Max Perutz labs AustriaSeminar room 20211 00 14 00Poster session 1 odd numbers Lunch and open discussionOperon Foyer14 00 14 30Responsible Conduct of Research Practical 1Conducted by the respective trainers14 30 19 00Practical 1 parallel sessions 1 High speed AFM2 Using Expansion Microscopy in cell biology3 Dissecting the role of cell geometry in surface mechanics by combining micropatterning and AFM indentation4 Live imaging of mouse pre implantation embryos and bio image analysis5 Simultaneous labeling of DNA RNA and proteins preserving chromosome morphology Is that possible 6 Build your fluorescence microscope DIY 7 High Content Screening Investigating DNA damage response and inflammation interplay8 Random walks in Biology9 Characterizing stem cells from human epidermis10 Volume CLEM unravels the sub cellular architecture of selected marine unicellular plankton11 Fluorescence Lifetime Imaging Microscopy FLIM applications19 00 20 15DinnerEMBL Canteen20 15Return to hotelEMBL Bus Stop Day 3 Tuesday 3 September 2024 Time Europe Berlin SessionLocation08 40 08 55Bus from ISG hotel to EMBL Bus Stop08 55 09 00Overview of the daySeminar room 20209 00 09 45Lecture Biophysics of molecular sociologyThomas Quail EMBL Heidelberg GermanySeminar room 20209 45 10 15Break10 15 11 00Lecture Heterogeneity in human skin cellsFiona Watt EMBL Heidelberg GermanySeminar room 20211 00 14 00Poster session II even numbers Lunch and open discussionOperon Foyer14 00 19 00Practical I continue parallel sessions 1 High speed AFM2 Using Expansion Microscopy in cell biology3 Dissecting the role of cell geometry in surface mechanics by combining micropatterning and AFM indentation4 Live imaging of mouse pre implantation embryos and bio image analysis5 Simultaneous labeling of DNA RNA and proteins preserving chromosome morphology Is that possible 6 Build your fluorescence microscope DIY 7 High Content Screening Investigating DNA damage response and inflammation interplay8 Random walks in Biology9 Characterizing stem cells from human epidermis10 Volume CLEM unravels the sub cellular architecture of selected marine unicellular plankton11 Fluorescence Lifetime Imaging Microscopy FLIM applications19 00 20 30Tapas dinnerATC Rooftop Lounge20 30Return to hotelEMBL Bus Stop Day 4 Wednesday 4 September 2024 Time Europe Berlin SessionLocation08 40 08 55Bus from ISG hotel to EMBL bus stop08 55 09 00Overview of the daySeminar room 20209 00 09 45Lecture Super resolution microscopy introductionTimo Zimmermann EMBL Heidelberg GermanySeminar room 20209 45 10 10Break10 10 10 55Lecture Emerging model systems for cell biologyGautam Dey EMBL Heidelberg GermanySeminar room 20210 55 11 20Break11 20 12 05Lecture Cell mechanicsAlba Diz Mu oz EMBL Heidelberg GermanySeminar room 20212 05 12 55Lunch and NetworkingEMBL canteen12 55 13 15Responsible Conduct of Research Practical 2Conducted by the respective trainers13 15 17 45Practical 2 parallel sessions 1 High speed AFM2 Using Expansion Microscopy in cell biology3 Dissecting the role of cell geometry in surface mechanics by combining micropatterning and AFM indentation4 Live imaging of mouse pre implantation embryos and bio image analysis5 Simultaneous labeling of DNA RNA and proteins preserving chromosome morphology Is that possible 6 Build your fluorescence microscope DIY 7 High Content Screening Investigating DNA damage response and inflammation interplay8 Random walks in Biology9 Characterizing stem cells from human epidermis10 Volume CLEM unravels the sub cellular architecture of selected marine unicellular plankton11 Fluorescence Lifetime Imaging Microscopy FLIM applications17 45 18 45DinnerEMBL canteen18 45Walk to hotel Day 5 Thursday 5 September 2024 Time Europe Berlin SessionLocation08 40 08 55Bus from ISG hotel to EMBL Bus Stop08 55 09 00Overview of the daySeminar room 20209 00 10 00Seminar DNA PAINTRalf Jungmann Max Planck Institute of Biochemistry GermanySmall Operon10 00 10 30Meet the SpeakerSmall Operon10 30 11 00Break11 0 0 11 45Lecture Phase separation in cell biologySara Cuylen H ring EMBL Heidelberg GermanySeminar room 20211 45 12 45Career lunchEMBL canteen12 45 13 15Group Photo13 15 14 15Seminar Imaging the mammalian embryo with light sheet microscopy The director s cutKate McDole MRC Laboratory of Molecular Biology United KingdomSeminar room 20214 15 19 15Practical 2 continue parallel sessions 1 High speed AFM2 Using Expansion Microscopy in cell biology3 Dissecting the role of cell geometry in surface mechanics by combining micropatterning and AFM indentation4 Live imaging of mouse pre implantation embryos and bio image analysis5 Simultaneous labeling of DNA RNA and proteins preserving chromosome morphology Is that possible 6 Build your fluorescence microscope DIY 7 High Content Screening Investigating DNA damage response and inflammation interplay8 Random walks in Biology9 Characterizing stem cells from human epidermis10 Volume CLEM unravels the sub cellular architecture of selected marine unicellular plankton11 Fluorescence Lifetime Imaging Microscopy FLIM applications19 15 20 30Pizza DinnerATC Rooftop Lounge20 30Return to hotelEMBL Bus Stop Day 6 Friday 6 September 2024 Time Europe Berlin SessionLocation08 40 08 55Bus from ISG hotel to EMBL Bus Stop08 55 09 00Overview of the daySeminar room 20209 00 09 45Lecture TheoryAnna Erzberger EMBL Heidelberg GermanySeminar room 20209 45 10 15Break10 15 11 15Seminar SimulationsFlorian Berger Utrecht University The NetherlandsSmall Operon11 15 11 45Meet the SpeakerSeminar room 20211 45 12 45LunchEMBL canteen12 45 13 30Seminar Computational modellingAlejandro Torres S nchez EMBL Barcelona Spain virtual speaker Small Operon13 30 14 15Responsible Conduct of Research Practical 3Conducted by the respective trainersSeminar room 20214 15 18 45Practical 3 parallel sessions 1 High speed AFM2 Using Expansion Microscopy in cell biology3 Dissecting the role of cell geometry in surface mechanics by combining micropatterning and AFM indentation4 Live imaging of mouse pre implantation embryos and bio image analysis5 Simultaneous labeling of DNA RNA and proteins preserving chromosome morphology Is that possible 6 Build your fluorescence microscope DIY 7 High Content Screening Investigating DNA damage response and inflammation interplay8 Random walks in Biology9 Characterizing stem cells from human epidermis10 Volume CLEM unravels the sub cellular architecture of selected marine unicellular plankton11 Fluorescence Lifetime Imaging Microscopy FLIM applications18 45 19 00Return to hotelEMBL Bus Stop19 00 21 00Dinner and drinks at ISG HotelISG Hotel Day 7 Saturday 7 September 2024 Time Europe Berlin SessionLocation08 40 08 55Bus from ISG hotel to EMBL Bus Stop08 55 09 00Overview of the daySeminar room 20209 00 09 45Lecture Small molecule fluorophores for biological imagingClaire Deo EMBL Heidelberg GermanySeminar room 20209 45 10 00Break10 00 10 45Lecture Expansion microscopyNiccol Banterle EMBL Heidelberg GermanySeminar room 20210 45 11 00Break11 00 11 45Lecture MeiosisSimone K hler EMBL Heidelberg GermanySeminar room 20211 45 12 45LunchEMBL canteen12 45 18 00Practical 3 continue parallel sessions 1 High speed AFM2 Using Expansion Microscopy in cell biology3 Dissecting the role of cell geometry in surface mechanics by combining micropatterning and AFM indentation4 Live imaging of mouse pre implantation embryos and bio image analysis5 Simultaneous labeling of DNA RNA and proteins preserving chromosome morphology Is that possible 6 Build your fluorescence microscope DIY 7 High Content Screening Investigating DNA damage response and inflammation interplay8 Random walks in Biology9 Characterizing stem cells from human epidermis10 Volume CLEM unravels the sub cellular architecture of selected marine unicellular plankton11 Fluorescence Lifetime Imaging Microscopy FLIM applications18 00 18 30Bus to DowntownEMBL Bus Stop18 30 22 30Course dinner and Downtown Heidelberg visitFlammkuchenhof Heidelberg Day 8 Sunday 8 September 2024 Free day Day 9 Monday 9 September 2024 Time Europe Berlin SessionLocation08 40 08 55Bus from ISG hotel to EMBL Bus Stop08 55 09 00Overview of the daySeminar room 20209 00 09 45Lecture Machine learning for image analysisAnna Kreshuk EMBL Heidelberg GermanySeminar room 20209 45 10 15Break10 15 11 15Seminar Cell ProfilerBeth Cimini Broad Institute of MIT and Harvard USASmall Operon11 15 11 45Meet the speakerSeminar room 20211 45 12 45LunchEMBL canteen12 45 13 30Lecture Correlative light electron microscopyYannick Schwab EMBL Heidelberg GermanySeminar room 20213 30 14 15Responsible Conduct of Research Practical 4 Image analysis and TheoryConducted by the respective trainers14 15 18 45Practical 4 Image analysis and Theory parallel sessions 1 Cell Profiler2 Image Processing Analysis with ilastik3 Mathematical modeling using random walksSeminar room 202 CTL Flexlab18 45 20 00DinnerEMBL canteen20 00Return to hotelEMBL Bus Stop Day 10 Tuesday 10 September 2024 Time Europe Berlin SessionSession08 40 08 55Bus from ISG hotel to EMBL Bus Stop08 55 09 00Overview of the daySeminar room 20209 00 10 00Seminar Cell sortingKeisuke Goda Goda Lab Tokyo JapanSmall Operon10 00 11 00Meet the speakerSeminar room 20211 00 11 30BreakSeminar room11 30 12 15Lecture Microscopy applied IJan Ellenberg EMBL Heidelberg GermanySeminar room 20212 15 13 15LunchEMBL canteen13 15 14 00Lecture TBCRainer Pepperkok EMBL Heidelberg GermanySeminar room 20214 00 14 45Responsible Conduct of Research Practical 5 Image analysis and TheoryConducted by the respective trainers14 45 19 15Practical 5 Image analysis and Theory parallel sessions 1 Cell Profiler2 Image Processing Analysis with ilastik3 Mathematical modeling using random walksSeminar room 202 CTL Flexlab19 15 19 45Feedback sessionSeminar room 20219 45 20 45DinnerEMBL canteen20 45Return to hotelEMBL Bus Stop Practical information Registration fees and motivation letter The course is limited to 30 participants For selection purposes please note that your application will not be considered without a letter of motivation Registration Registration fees include admission course materials meals and coffee breaks This EMBO course includes accommodation and transportation to and from the ISG Hotel to the venue Academia 500PhD Student 500Industry 1000 A letter to support your visa application will be issued on request once payment of the registration fee is confirmed We recommend that you book your visa appointment as soon as possible to avoid any delay with your visa application Confirmation and payment The registration fee should be paid only after acceptance to the course The results will be announced approximately 2 3 weeks after the application deadline Motivation letter submission After you have logged in and successfully registered you will receive an email asking you to submit your motivation letter Click on the link provided and enter your motivation letter in the text box provided Alternatively you can submit your motivation letter by clicking on the link on the confirmation page directly after registering Instructions Include your relevant skills experience and qualifications showing why you would be suitable for the course Explain why you would like to attend including what you can contribute and how you think you will benefit from the course Please note The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised For detailed instructions please watch our video on how to submit a course motivation letter Further details For further information about registration and motivation letter submission please refer to the FAQ page Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of registration fee waivers travel grants and childcare grants Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course Travel grant The travel grant will cover the cost of travel airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Course within Europe up to 1000 for participants travelling to an EMBL Course from outside Europe up to 500 for any participant travelling to an EMBO Practical Course up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Practical Course up to 700 for any participant working in Croatia Czech Republic Estonia Greece Hungary Italy Lithuania Luxembourg Poland Slovenia and Turkey travelling to an EMBO Practical Course Registration fees are only covered for EMBO Practical Courses The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant There is the possibility to apply for a childcare grant to offset child care costs incurred by participants speakers trainers and organisers when attending a course Eligible costs include but are not limited to fees for a babysitter or child care facility and travel costs for a caregiver Please note that priority will be given to early stage researchers There is a limited amount of funding available for the childcare grants and funds will be distributed amongst eligible applicants Boehringer Ingelheim Fonds travel grant Applies to selected courses only Availability will be indicated during the motivation letter submission process This grant covers costs related to your attendance at the course registration travel and accommodation costs The grant is restricted to PhD students and postdocs who conduct basic biomedical research Whether you are eligible to apply for a travel grant depends on when you received your university entrance qualification e g Abitur A Levels High School Diploma Final State Examination for PhD and MD students as well as graduates the university entrance qualification must not have been obtained more than 11 years ago at the time of the envisaged course for postdocs the university entrance qualification must not have been obtained more than 13 years ago at the time of the envisaged course Application You may apply for financial assistance when submitting your motivation letter for courses In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application For the Boehringer Ingelheim Fonds Travel Grant there is a pre application question during the motivation letter submission process and if selected you will be requested to complete a standard form and documentation consisting of your travel expense estimation Selection The scientific organisers will select the recipients of registration fee waivers and travel grants during the motivation letter or abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection for registration fee waivers and travel grants is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Childcare grants will be allocated in the same timeframe 6 8 weeks before the event start date Please note that priority will be given to early stage researchers Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details See our list of external funding opportunities and for further information about financial assistance please refer to the FAQ page Accommodation and travel Travel information For travel information please see here If you are travelling to the conference within Germany then you are eligible for the Deutsche Bahn Event Ticket called the Veranstaltungsticket in German This will result in a lower ticket price if your travel distance to Heidelberg is more than 100 km You need to provide proof of your event attendance when purchasing the ticket For more information in English see here or in German see here You can book your ticket here Hotel Accommodation in twin rooms including breakfast is included in the registration fee Accommodation has been booked for you at the ISG Hotel for the default dates of 1 to 10 September 10 nights In case you would like to have a single room please let the hotel know and note that you will be required to pay directly an additional cost of 24 per night availability of single rooms may be limited Any additional nights need to be booked and paid for by you We recommend that all course participants stay at the ISG Hotel which is the dedicated hotel for the course Local transport Shuttle buses will go from the ISG Hotel to EMBL and back mornings and evenings A bus schedule and location of the bus stops will be made available prior to the meeting Further details Address EMBL Heidelberg Meyerhofstra e 1 69117 Heidelberg GermanyFor more information about accommodation and travel please refer to the FAQ page On site information Catering All meals and coffee breaks are included in the registration fee Our catering staff will prepare a wide variety of vegetarian meals meat and fish dishes soups pasta fresh fruit and vegetables as well as a variety of desserts Please wear your badge at all times when serving yourself No food or drinks are allowed in the laboratories Electricity and charging station In most places the electricity is 220 volts AC 50 cycles An adaptor and a plug that fits the German socket may be needed for your appliances laptop i e American Japanese etc A USB charging station for electronic devices is available at the registration desk EMBL Merchandise If you are interested in purchasing EMBL merchandise products presented in the glass display in the registration area please email the EMBL shop to place an order or get in contact with your Course Organiser Kindly note the EMBL shop is only open upon request and all purchases must be made in cash Euros only Health and safety notes Please read EMBL s COVID 19 safety policy for on site events Do not smoke in any EMBL building Eating and drinking is prohibited in all laboratories Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required The first aid room is located next to the ATC Registration Desk room 10 205 Dial the Emergency number 222 from any EMBL internal phone only Where is the accident What happened How many injured Emergency number 06221 387 7821 from mobile phones Please report all accidents to the conference officer at the registration desk In case of fire Press the nearest fire alarm button or the Emergency number 222 from any internal phone A loud fire alarm will go off if an evacuation is required On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting points Do not use the lifts Beyond first aid Please remember to bring your own medication if needed to the conference Note that the next pharmacy is a 4 minute drive from the EMBL but for many medications you will be required to see a doctor to get a prescription Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg In any case the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary Internet Wi Fi is available on campus Log in using the EMBL Events network and the event specific password which will be provided on site The eduroam network secure worldwide roaming access service developed for the international research and education community is also available Lost and found Lost and Found items are kept at the registration desk until the end of the conference Luggage There are lockers available on site to store your luggage which require a 2 EURO coin to operate There is another luggage room on level E0 which is free to use but remains unlocked during the conference Nursing room There is a nursing room available in the ATC Rooftop Lounge on level A29 Photography During the conference an EMBL Photographer may be taking photos If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Printing We can help to print your boarding pass train ticket Please send it to events embl de and collect your print outs at the registration desk Room for prayer yoga and meditation There is a room for prayer meditation and yoga located on level E0 behind the Auditorium Please be respectful of others using the room Sightseeing A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing Travel to and from the venue During the event we provide conference shuttle buses to and from EMBL In addition there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time Information on the shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page Map to walk from ISG Hotel to EMBL Additional information Address EMBL Heidelberg Meyerhofstra e 1 69117 Heidelberg Germany ATC orientation map Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page Technical requirements and event software delete the technical requirements part if it is not a computer based course in the courtyard room as well as change label of the details section to only Event Software Technical requirements Below you will find the software and technical requirements for this course Participants need to bring their own laptops which will be used to remotely access EMBL virtual machines with pre installed software You will need admin rights to install the software required to access the virtual machines If you do not have admin rights please contact your technical support team in advance to make sure the software can be installed If you have a non standard HDMI port other than type A you need to bring an adaptor Keyboard and PC mouse are available for use with a standard USB port If you have a different port type such as USB C you will need to bring your own Event software The EMBL eCampus learning platform will be used to collaborate communicate and network with all of the course participants All participants will receive information on how to join shortly before the course We recommend using Chrome Safari or Mozilla Firefox browsers for eCampus Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page COVID 19 related questions COVID 19 information for on site events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other events or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9...

Niccolò Banterle, Beth Cimini, Simone Koehler

EMBO Practical Course

EMBL Heidelberg

24 August - 27 August 2024

Transcription and chromatin

Edit

August 24, 2024 00:002024ConferenceEMBL Heidelberg, Virtual

Description OverviewSpeakersFinal programmePractical informationSponsorsMedia kitPre conference workshop Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Conference overview The EMBL Transcription and chromatin conference has a long standing tradition in shaping the field of transcriptional regulation The meeting brings together leading experts covering all aspects of transcription including cis regulatory function long range regulation 3 dimensional looping the basal transcriptional machinery RNA polymerase regulation and function nucleosome positioning chromatin modifications chromatin remodelling and epigenetic inheritance of transcriptional silencing The meeting contains many talks selected from the abstracts that are interspersed with invited speakers discussing the latest breakthroughs in transcriptional regulation The conference is designed to promote interactive discussions at both the talks and poster sessions Given the excellent lineup of speakers and the meeting s outstanding reputation this is a must attend for anyone interested in cutting edge research in transcription Topics General basal transcriptional machinery Pol II function pausing and the role of RNA in transcription Chromatin modifications and transcription Chromatin readers writers and epigenetic regulation Condensates hubs and speckles Transcription regulation during embryonic development and disease Genome topology and three dimensional regulation Quantatitive and theoretical approaches Imaging of transcription and genome What past participants say about the conference I would say that I am privileged to have been in the most prestigious institute on the planet It was my dream come true moment during the conference I sincerely thank EMBL for providing me conference registration grant otherwise it would never have been possible for me to reach EMBL I would urge every life sciences student to be at EMBL at least once it will be a lifetime experience for sure as it was for me Haneul Yoo Max Planck Institute of Immunobiology and Epigenetics Germany I am new to the field and attended the EMBL conference to meet people and learn about the field I learned a ton during the four days at the ATC and I also made new friends and contacts who I look forward to meeting again in future conferences Marion Turpin Institute Genetics Development of Rennes France A pleasure to attend my first EMBL Transcription and Chromatin conference Also very happy of having the opportunity to share my team s work networking and learning from incredible researchers in the field Elena G mez Mar n Andalusian Molecular Biology and Regenerative Medicine Centre Spain Speakers Karen Adelman Harvard Medical School USA Deborah Bourc his Institut Curie France Caroline Dean John Innes Centre UK Beat Fierz Ecole polytechnique f d rale de Lausanne Switzerland Thomas Gregor Princeton University USA Anja Groth University of Copenhagen Denmark Cigall Kadoch Dana Farber Cancer Institute and Harvard Medical School USA Gary Karpen University of California Berkeley USA Jop Kind Hubrecht Institute The Netherlands Mounia Lagha Institut de G n tique Mol culaire de Montpellier France Tineke Lenstra Netherlands Cancer Institute The Netherlands Karolin Luger University of Colorado Boulder USA Jan Michael Peters Research Institute of Molecular Pathology Austria Yang Shi Ludwig Cancer Research United Kingdom Ali Shilatifard Northwestern University Feinberg School of Medicine USA Bas van Steensel Netherlands Cancer Institute The Netherlands Peter Verrijzer Erasmus University Rotterdam The Netherlands Carl Wu Johns Hopkins University USA Joanna Wysocka Stanford University USA Yanhui Xu Fudan University China Yi Zhang Harvard University USA Scientific Organisers Shelley Berger University of Pennsylvania USA Eileen Furlong EMBL Heidelberg Germany Luca Giorgetti Friedrich Miescher Institute for Biomedical Research Switzerland J rg M ller Max Planck Institute of Biochemistry Germany Conference Organiser Nathalie Sneider EMBL Heidelberg Germany Final programme Are you on social media Post using EMBLTranscript and don t forget to tag EMBLEvents Please note that the programme is subject to change All talks are planned to take place on site only For registered participants recorded talks will be accessible on demand for 2 weeks after the end of the event unless indicated otherwise Recorded talks please note that for this event we expect 13 out of 21 invited speaker talks to be recorded and 21 out of 29 short talks to be recorded Details of which speaker talks will will not be available is shown in the final programme Please find the poster listing here Day 1 Saturday 24 August 2024 Time Europe Berlin Speaker14 30 16 30Arrival and registration15 00 15 50Pre conference workshop with LUMICKS16 30 16 40Opening remarks16 40 18 10Session 1Chairs Eileen Furlong EMBL Heidelberg Germany and J rg M ller Max Planck Institute of Biochemistry Germany16 40 17 00The rapidly expanding histone universeKarolin Luger University of Colorado Boulder and HHMI United States of America17 00 17 20Molecular insight into transcription elongation regulatory mechanisms and epigenetics deliver critical targets for cancer therapeuticsAli Shilatifard Northwestern University United States of AmericaNot available on demand17 20 17 35Structural basis of transcription and pausing by RNAPII in chromatinShun ichi Sekine RIKEN Japan17 35 17 50Single molecule dynamics of pioneer transcription factors interrogating chromatin in living cellsWulan Deng Peking University China17 50 18 10The epigenetic reader Phf2 is positioned in the genome by cohesinJan Michael Peters Research Institute of Molecular Pathology Austria18 10 19 45Dinner in the Canteen19 45 21 15Pub Quiz in the Canteen19 45 22 00After dinner drinks in the Rooftop Lounge and Foyer Day 2 Sunday 25 August 2024 Time Europe Berlin Speaker09 00 12 25Session 2Chairs Karolin Luger University of Colorado Boulder USA Peter Verrijzer Peter Verrijzer Erasmus University Rotterdam The Netherlands09 00 09 20Integrator mediated control of stress responsesKaren Adelman Harvard Medical School United States of AmericaNot available on demand09 20 09 35Structural basis of chromatin transcriptionLucas Farnung Harvard Medical School United States of AmericaNot available on demand09 35 09 50Direct recruitment of RNA Polymerase II by NANOG to chromatinNick Mullin The University of Edinburgh United Kingdom09 50 10 05Basal transcription factor TFIID in neurodevelopment and neurodegeneration Marc Timmers German Cancer Research Center DKFZ Germany10 05 10 25Structural Insights into Transcription InitiationYanhui Xu Fudan University China10 25 11 00Coffee Break11 00 11 20Dissecting the dynamics of coordinated active transcriptional repression in a multicellular organismMounia Lagha French National Centre for Scientific Research CNRS France11 20 11 35Chip ping away at zygotic genome activationCharalampos Galouzis EMBL Heidelberg Germany11 35 11 50HIV 1 promoter bursting in T lymphocytes and its implication in latency regulationEugenia Basyuk MFP UMR 5234 CNRS University of Bordeaux France11 50 12 05A conserved cis acting range extender element mediates extreme long range enhancer activity in mammalsGrace Bower University of California Irvine United States of America12 05 12 25Location location location Probing the functional landscape of a genomic locusBas van Steensel Oncode Institute Netherlands Cancer Institute The Netherlands12 25 14 00Lunch14 00 16 30Poster Session 1 odd with coffee and refreshments16 30 18 45Session 3Chaired by Yang Shi Ludwig Cancer Research United Kingdom Cigall Kadoch Dana Farber Cancer Institute and Harvard Medical School USA16 30 16 50The biogenesis dynamic maintenance and function of open chromatinCarl Wu Johns Hopkins University United States of America16 50 17 05Two distinct chromatin modules regulate 17proinflmmatory gene expressionKarsten Rippe German Cancer Research Center DKFZ Not available on demand17 05 17 20Long range TF co occupancy identifies functional dependencies between cis regulatory elementsArnaud Krebs EMBL Heidelberg Germany17 20 17 35The RNA binding protein Hangover associates with chromatin and regulates transcriptionAlexander Brehm Philipps University of Marburg Germany17 35 17 55A new spin to chromatin regulation of retrotransposonsD borah Bourc his Institut Curie France18 00 20 00Dinner in the Canteen20 00 22 00After dinner drinks in the Rooftop Lounge and Foyer Day 3 Monday 26 August 2025 Time Europe Berlin Speaker09 00 12 25Session 4Chaired by Karen Adelman Harvard Medical School USA Jan Michael Peters Research Institute of Molecular Pathology Austria09 00 09 20Chromatin replication and epigenome maintenanceAnja Groth Novo Nordisk Foundation Center for Protein Research University of Copenhagen DenmarkNot available on demand09 20 09 35Structural insight into the mechanisms of Polycomb Repressive Complex 1Maria Ciapponi Max Planck Institute of Biochemistry Germany09 35 09 50Chromatin tethering by the Trithorax homolog MLL2 during the ESC naive to primed transitionFrancis Stewart University of Cambridge United Kingdom09 50 10 05Molecular kinetics of transcription regulation during embryonic developmentMustafa Mir University of Pennsylvania United States of America10 05 10 25Imaging real time single molecule dynamics in genome regulationBeat Fierz cole Polytechnique F d rale de Lausanne EPFL SwitzerlandNot available on demand10 25 11 00Coffee Break11 00 11 20EMBO Young Investigator LectureTranscription factor exchange enables prolonged transcriptional burstsTineke Lenstra Netherlands Cancer Institute The Netherlands11 20 11 35Enhancer redundancy sustains transcriptional memories in metastatic cellsAlessio Zippo University of Trento Italy11 35 11 50Transient promoter interactions modulate developmental gene activationAngelika Feldmann German Cancer Research Center DKFZ GermanyNot available on demand11 50 12 05Enhancer cooperativity can compensate for loss of activity over large genomic distancesChrista Buecker Max Perutz Labs Vienna University of Vienna Austria12 05 12 25Spatial organization of a gene locus around transcription factor clusters in Drosophila embryosThomas Gregor Princeton University United States of America Institut Pasteur France12 25 14 00Vegetarian lunch and Meet the Editors between 13 00 14 00 in the FoyerChiara Anania and Hui Hua from Springer NatureEsther Schnapp and Hannah Sonntag from EMBO Lavinia Arseni from FEBS Letters14 00 16 30Poster Session 2 even with coffee and refreshments16 30 18 00Session 5Chaired by Gary Karpen University of California Berkeley USA Deborah Bourch has Institut Curie France16 30 16 50 Measuring single cell chromatin transitions in timeJop Kind Hubrecht Institute Royal Netherlands Academy of Arts and Sciences Oncode Institute University Medical Center Utrecht The Netherlands16 50 17 05Circadian rhythm tempers establishment of X chromosome inactivationMarnie Blewitt Walter and Eliza Hall Institute of Medical Research AustraliaNot available on demand17 05 17 20Functional redundancy and pathogenic mechanisms in RING1 and RNF2 variants Insights from H2AK119ub1 dosage in human neural developmentStephanie Bielas University of Michigan Medical School United States of America17 20 17 35Active state structures of the MSL reader writer complex reveal the molecular basis of histone H4K16 acetylationSebastian Eustermann EMBL Heidelberg Germany17 35 17 55Structure and Function of Mammalian SWI SNF Chromatin Remodeling Complexes in Health and DiseaseCigall Kadoch Dana Farber Cancer Institute Harvard Medical School United States of AmericaNot available on demand18 00 20 00Dinner in the Canteen20 00 22 00After dinner drinks in the Rooftop Lounge and Foyer Day 4 Tuesday 27 August 2024 Time Europe Berlin Speaker09 00 12 25Session 6Chaired by Anja Groth University of Copenhagen Denmark Ali Shilatifard Northwestern University Feinberg School of Medicine USA09 00 09 20Affinity hierarchies and amphiphilic proteins underlie the co assembly of nucleolar and heterochromatin condensatesGary Karpen University of California Berkeley United States of America09 20 09 35Elucidating the role of cohesin loop extrusion in transcriptional dynamics and enhancer promoter communicationKarissa Hansen University of California San Francisco United States of AmericaNot available on demand09 35 09 50Mechanisms of transcription control by distal enhancers from high resolution single gene imagingAlexandros Pertsinidis Memorial Sloan Kettering Cancer Center United States of America09 50 10 05Histone variant H2BE enhances chromatin accessibility in neurons to promote synaptic gene expression and long term memoryErica Korb University of Pennsylvania United States of America10 05 10 25Developmental stage specific functions and mechanisms of Polycomb silencingYi Zhang Boston Childrens Hospital United States of AmericaNot available on demand10 25 11 00Coffee Break11 00 11 20The tail wagging the dog function of the p53 IDR in target gene selectionPeter Verrijzer Erasmus University Medical Center The NetherlandsNot available on demand11 20 11 35Fueling memory the metabolic enzyme ACSS2 as a modulator of neuronal resilienceDesi Alexander Washington University School of Medicine in St Louis United States of America11 35 11 50Systematic assessment of ISWI subunits shows that NURF creates local accessibility for CTCFFrancesca Masoni Friedrich Miescher Institute for Biomedical Research SwitzerlandNot available on demand11 50 12 05Enhancer control of transcriptional activity via modulation of burst frequencyJana T nnermann Friedrich Miescher Institute for Biomedical Research Switzerland12 05 12 30Termination or read through co transcriptional processing linked to epigenetic silencingCaroline Dean John Innes Centre United Kingdom12 25 14 00Lunch14 00 16 30Poster Session 3 odd and even with coffee and refreshments16 30 19 00Session 7Chaired by Shelley Berger University of Pennsylvania USA Luca Giorgetti Friedrich Miescher Institute for Biomedical Research Switzerland16 30 16 50To be presented on siteYang Shi Ludwig Institute for Cancer Research Oxford University United KingdomNot available on demand16 50 17 05Sequence signature of evolutionary activation of distal regulatory elements in primate astrocytesAleksandra Pekowska Nencki Institute of Experimental Biology Polish Academy of Sciences Poland17 05 17 20Dynamic PRC1 CBX8 stabilizes a porous structure of chromatin condensatesChen Davidovich Monash University Australia17 20 17 35Transposons in 3D loop extrusion and compartmentalization affect the regulatory capacity of repeat elementsElzo de Wit The Netherlands Cancer Institute The Netherlands17 35 17 55How do transcription factors tolerate long polyglutamine tracts Joanna Wysocka Stanford University United States of AmericaNot available on demand17 55 18 10Closing remarks and poster prizes18 10 20 30Conference dinner in the Canteen20 30 23 30Conference party with live music from The Wright Thing Practical information Registration fees and abstract submission Late poster abstracts for this conference will still be considered Please contact nathalie sneider embl org if you are interested in presenting a poster On site registration fees include admission conference materials meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Virtual registration fees include access to all of the talks livestreamed and on demand and facility to submit questions On site Academia 800On site PhD Student 700On site Industry 1000On site Journal Editors 300Virtual Academia 225Virtual PhD Student 175Virtual Industry 275 Editors from scientific journals are allowed to attend at a reduced rate but asked to contribute to the conference in return by taking part in meet the editors sessions or other planned activities within the programme A letter to support your visa application will be issued on request once payment of the registration fee is confirmed We recommend that you book your visa appointment as soon as possible to avoid any delay with your visa application Accredited journalists may be eligible to register for complimentary press registration Registrants may be required to provide accreditation or equivalent proof of press membership after registration Please contact Nathalie Sneider for more information Please note that we do not offer complimentary registrations for editors of scientific journals Confirmation and payment Registration will be on a first come first served basis Your place can only be confirmed after payment of the registration fee If you are added to our waiting list please consider taking advantage of our offerings to participate virtually On site participants Types of payments accepted are international bank transfers and credit card payments Virtual participants We are only able to accept card payments In exceptional cases we can accept bank transfers Please contact events embl de for details Abstract submission Only participants registering to attend the on site event are eligible to submit an abstract Abstracts will not be accepted from virtual participants After registration you can submit your abstract via a separate link that will be provided in the email confirmation Alternatively you can access the link on the confirmation page directly after registering The same login credentials are used for both processes Please note Abstract body The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised Title The title should not exceed 20 words Only the first word of the title should start with a capital letter and the rest should be lowercase Authors and affiliations Please fill in the author s details as requested in the online form The compulsory fields are First Name Last Name Organisation Name Affiliation or Company Country and Email Kindly mark only one author in the role of First Author and please don t forget to indicate who will be the Presenter Please enter your co authors correctly via the system by adding accounts together with their organisation institute Do not copy paste them into the body of the abstract text as they will not be indexed in the abstract book Presentation types When submitting your abstract you can apply for an oral or poster presentation A selection process will take place with the results announced 2 3 weeks after the abstract submission deadline For detailed instructions on how to submit a conference abstract follow the instructions provided in this video Please check our FAQs pages for further information on how to submit an abstract Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of registration fee waivers travel grants and childcare grants Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course or conference Travel grant The travel grant will cover the cost of travel to an on site event airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from within Europe up to 1000 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from outside Europe up to 500 for any participant travelling to an EMBO Workshop up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Workshop up to 700 for any participant working in Croatia Czech Republic Estonia Greece Hungary Italy Lithuania Luxembourg Poland Slovenia and Turkey travelling to an EMBO Workshop Registration fees are only covered for EMBO Workshops The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant There is the possibility to apply for a childcare grant to offset child care costs incurred by participants speakers and organisers when attending a conference Eligible costs include but are not limited to fees for a baby sitter or child care facility and travel costs for a caregiver Please note that priority will be given to early stage researchers In order to apply for this grant you must be registered by the abstract submission deadline There is a limited amount of funding available for the childcare grants and funds will be distributed amongst eligible applicants Application On site participants You may apply for financial assistance when submitting your abstract In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Virtual participants If you are attending virtually you can apply for financial assistance in the submission portal by the abstract deadline Read the instructions on how to apply for financial assistance Only submissions for financial assistance will be accepted Presentation abstracts cannot be submitted here and will be declined In your application you will be asked to summarise your current work answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Selection The scientific organisers will select the recipients of registration fee waivers and travel grants during the motivation letter or abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection for registration fee waivers and travel grants is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Childcare grants will be allocated in the same timeframe 6 8 weeks before the event start date Please note that priority will be given to early stage researchers Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details View our list of external funding opportunities and information on attending a conference as an event reporter For further information about financial assistance please refer to the FAQ page Accommodation and travel Accommodation is not included in the conference registration fee The hotels below have rooms on hold for participants until Saturday 27 July 2024 in some cases at special rates Please email the hotel directly quoting the booking code TRM24 01 to confirm the exact price of the room Hotel AnlageHotel ibis HeidelbergHotel Bayrischer HofExzellenz Hotel Boarding HouseB B HotelHotel Holl nder HofHilton Heidelberg Travel information For travel information please see here If you are travelling to the conference within Germany then you are eligible for the Deutsche Bahn Event Ticket called the Veranstaltungsticket in German This will result in a lower ticket price if your travel distance to Heidelberg is more than 100 km You need to provide proof of your event attendance when purchasing the ticket For more information in English see here or in German see here You can book your ticket here Conference shuttle buses Conference shuttle buses are free of charge for participants and depart from designated bus stops near the hotels to EMBL and back mornings and evenings Please find the bus schedule here updated as of 26 August The bus stops for this conference are Staycity Aparthotel Speyerer Str 7 Kurf rsten Anlage Opposite Main Train Station Premier Inn Kurf rsten Anlage 23 Neckarm nzplatz Heidelberg Tourist Information Peterskirche Bus stop Hilton Hotel front entrance View Conference shuttle bus stops and hotels in a larger map Please note that not every bus stop will be used for every event Further details Address EMBL Meyerhofstra e 1 69117 Heidelberg Germany For more information about accommodation and travel please refer to the FAQ page On site information Catering All meals and coffee breaks are included in the registration fee Our catering staff will prepare a wide variety of vegetarian meals meat and fish dishes soups pasta fresh fruit and vegetables as well as a variety of desserts Please wear your badge at all times when serving yourself No food or drinks are allowed in the auditorium Charging lockers There are lockers available next to the stairs leading down into the Auditorium You will find some of those equipped with sockets to charge your smartphone tablet etc Electricity and charging station In most places the electricity is 220 volts AC 50 cycles An adaptor and a plug that fits the German socket may be needed for your appliances laptop i e American Japanese etc A USB charging station for electronic devices is available at the registration desk EMBL merchandise If you are interested in purchasing EMBL merchandise products presented in the glass display in the registration area please email the EMBL shop to place an order or get in contact with your Course Organiser Kindly note the EMBL shop is only open upon request and all purchases must be made in cash Euros only Health and safety notes Please read EMBL s COVID 19 safety policy for on site events Do not smoke in any EMBL building Eating and drinking is prohibited in the Auditorium and all laboratories Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required The first aid room is located next to the ATC Registration Desk room 10 205 Dial the Emergency number 222 from any EMBL internal phone only Where is the accident What happened How many injured Emergency number 06221 387 7821 from mobile phones Please report all accidents to the conference officer at the registration desk In case of fire Press the nearest fire alarm button or the Emergency number 222 from any internal phone A loud fire alarm will go off if an evacuation is required On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting points Do not use the lifts Beyond first aid Please remember to bring your own medication if needed to the conference Note that the next pharmacy is a 4 minute drive from the EMBL but for many medications you will be required to see a doctor to get a prescription Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg In any case the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary Internet Wi Fi is available on campus using the EMBL Events network and the event specific password which will be provided on site The eduroam network secure worldwide roaming access service developed for the international research and education community is also available Lost and found Lost and Found items are kept at the registration desk until the end of the conference Luggage There are lockers available on site to store your luggage which require a 2 EURO coin to operate There is another luggage room on level E0 which is free to use but remains unlocked during the conference Nursing room There is a nursing room available in the ATC Rooftop Lounge on level A29 Photography During the conference an EMBL Photographer may be taking photos If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Printing We can help to print your boarding pass train ticket Please send it to events embl de and collect your print outs at the registration desk Room for prayer yoga and meditation There is a room for prayer meditation and yoga located on level E0 behind the Auditorium Please be respectful of others using the room Sightseeing A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing Travel to and from the venue During the event we provide conference shuttle buses to and from EMBL In addition there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time Information on the conference shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page Useful German expressions HelloHalloGoodbyeAuf Wiedersehen formal Tsch ss informal Good morningGuten MorgenGood afternoonGuten TagGood eveningGuten AbendGood nightGute NachtI m sorryEs tut mir leidExcuse me Entschuldigen SieHow are you Wie gehts I m fine thanks And you Mir geht es gut danke Und Dir Ihnen What is your nameWie hei en Sie formal Wie hei t Du informal My name isIch hei e Do you speak EnglishSprechen Sie englisch I don t understandIch verstehe nichtPlease speak more slowlyK nnen Sie bitte langsamer sprechenThank youDankesch nWhere is the toilet Wo ist die Toilette Please call me a taxiBitte rufen Sie mir ein TaxiHow do I get to Wie komme ich zum zur A beer two beers pleaseEin Bier zwei Bier bitteA glass of red white wine pleaseEin Glas Rot Weisswein bitteThe menu pleaseDie Speisekarte bitteIs there a local speciality Gibt es eine Spezialit t aus dieser Gegend I m vegetarianIch bin VegetarierIt was deliciousEs war hervorragendThe bill pleaseDie Rechnung bitteI have a headacheIch habe KopfschmerzenI have a sore throatIch habe HalsschmerzenMy stomach hurtsIch habe MagenschmerzenI m allergic toIch bin allergisch gegenI need a doctor who speaks EnglishIch brauche einen Arzt der englisch spricht Virtual participation What s included Access to all the livestreamed talks Video library of the recorded talks during the event and for two weeks afterwards Please note at the request of individual speakers some talks are not recorded Facility to submit questions Please note that only on site participants are able to submit abstracts and participate in the poster sessions Event platform We are using an event platform for this conference More information about the platform will be shared ahead of the conference Guidelines Do not broadcast the conference to unregistered participants You are encouraged to tweet and post about the event Tweet unless the speaker specifically says otherwise but be mindful of unpublished data Please do not capture transmit or redistribute data presented at the meeting Additional information can be found in our Code of Conduct Health and well being It is important to stay healthy and move around especially when you are attending an event virtually We have put together a few coffee break stretches and yoga videos in the conference platform for you to enjoy during the event How to ask questions Please use the Q A function in the event platform If you have any other questions you can go to the Help Desk in the event platform Click on more on the top menu and click Help Desk Time zone The programme is planned based on the Europe Berlin time zone unless otherwise stated Please take your time zone into consideration when planning your attendance Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for participants page COVID 19 related questions COVID 19 information for on site events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Silver sponsor Bronze sponsor Event sponsors Active Motif GoodBot New England Biolabs NIPPON Genetics EUROPE Event supporter Media partners EMBO Journal an EMBO Press Journal Development The Company of Biologists Journal FEBS Letters FEBS Open Bio Genes and Development a Cold Spring Harbor Journal Genome Research a Cold Spring Harbor Journal International Union of Biochemistry and Molecular Biology Medinformatics a Bon View Publishing journal Open Biology a Royal Society journal PLOS Biology a PLOS journal Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information on sponsoring possibilities If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9 Leaderboard 729 90 Pre conference workshop For on site participants only This industry webinar will be hosted by our sponsor LUMICKS B V before the EMBL Conference Transcription and chromatin on Saturday 24 August 2024 15 00 16 00 Participation in this workshop is free of charge for registered on site conference attendees The workshop will take place in the Main Auditorium ABSTRACT Single molecule biology unravelling the mechanisms underlying chromatin organization and transcription Daphne Jurriens Roman Renger Ann MukhortavaLUMICKS B V Amsterdam The Netherlands The structure regulation maintenance and organization of chromatin is critical to cellular function Errors in the underlying molecular mechanisms have been shown to play a major role in diseases such as cancer Hence insights into the molecular details are needed to advance our understanding improve biological models and develop novel therapeutics Dynamic single molecule technologies offer an exciting opportunity to meet these challenges and to study protein dynamics function and activity in real time Here we present our efforts for enabling discoveries in chromatin and epigenetics research With the C TrapTM we provide an easy to use instrument that combines optical tweezers fluorescence microscopy and microfluidics It allows you to visualize the interaction and activity of individual protein complexes with and on chromatin in real time assemble chromatin structures in situ and to directly measure the mechanical forces that determine chromatin architecture We will cover several example studies in which our technology biochemistry and data analysis solutions have enhanced the understanding of fundamental processes of chromatin biology ranging from DNA damage repair to transcription to nucleosome remodeling Furthermore we will demonstrate how our platform can be utilized to assess the mechanical properties of individual chromatin fibers and complete chromosomes under various conditions related to physiology and disease...

Shelley Berger, Eileen Furlong, Luca Giorgetti, Jürg Müller

EMBL Heidelberg, Virtual

18 August - 26 August 2024

Advances in cryo-electron microscopy and 3D image processing

Edit

August 18, 2024 00:002024CourseEMBL Heidelberg

Description OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview Course overview Technology advances in cryo electron microscopy cryoEM over the last decade have transformed our understanding of biomolecular structures across different spatial scales CryoEM has unique capabilities for obtaining structural information in situ within complex cellular environments and to obtain atomic level structures of biologically flexible and heterogeneous macromolecular assemblies With the advent of the cryoEM resolution revolution the method has undergone a tremendous growth in user base Yet emerging breakthroughs such as new correlated imagine technologies and in AI based image processing demonstrate the potential for cryoEM to make another leap forward towards new frontiers Therefore in depth advanced training is essential to ensure future generations can adapt such emerging technologies to expand into new areas of biological research This course provides the theoretical and practical foundations of advanced cryoEM techniques from sample preparation to data collection to image processing Audience To meet the exceptional demand of the field for advanced training this course is aimed at PhD students and postdocs with basic experience in cryoEM and 3D image processing Modules resources During this course we will focus on the following aspects Single particle reconstruction cisTEM Relion cryoSPARC Subtomogram averaging Atomic models model building and integrative modeling Microscopy cryoEM ET and cryo FIB Latest developments in instrumentations Learning outcomes The course will enable participants to seamlessly integrate single particle analysis and tomography approaches to their cutting edge research disseminate their gained expertise to colleagues and eventually to innovate cryoEM methods beyond the state of the art What past participants say about the course This a world class course The access to experts and cutting edge techniques is incredible Corbin Black McGill University Canada This event has been granted the following EMBO sustainability badge Grade 2 of 3 The EMBL Imaging Centre training activities are generously supported by the Boehringer Ingelheim Foundation Speakers Speakers trainers and staff Tanmay Bharat MRC Laboratory of Molecular Biology UK Alister Burt Genentech USA Bridget Carragher Chan Zuckerberg Imaging Institute USA Virtual speaker Svetlana Dodonova EMBL Heidelberg Germany Johannes Elferich University of Massachusetts Medical School USA Sebastian Eustermann EMBL Heidelberg Germany Ryan Feathers Princeton University USA Simon Fromm EMBL Heidelberg Germany Robert Glaeser Lawrence Berkeley National Laboratory USA Virtual speaker Michal Grzadkowski Princeton University USA Nikolaus Grigorieff University of Massachusetts Medical School USA Hui Guo Max Planck Institute of Biochemistry Germany Thomas Hoffmann EMBL Heidelberg Germany Jan Kosinski EMBL Hamburg Germany Wanda Kukulski University of Bern Switzerland Julia Mahamid EMBL Heidelberg Germany Simone Mattei EMBL Heidelberg Germany Kyle Morris EMBL EBI UK Colin Palmer UKRI STFC UK Lori Passmore MRC Laboratory of Molecular Biology UK Cristina Paulino Heidelberg University Germany Rishwanth Raghu Princeton University USA Higor Rosa EMBL Heidelberg Germany Christopher Russo MRC Laboratory of Molecular Biology UK Carsten Sachse Forschungszentrum J lich Germany Sjors Scheres MRC Laboratory of Molecular Biology UK Virtual speaker Anna Steyer EMBL Heidelberg Germany Yi Sun EMBL Heidelberg Germany Dimitry Tegunov Genentech USA Beata Turonova Max Planck Institute of Biophysics Germany Virtual speaker Andriko von K gelgen MRC Laboratory of Molecular Biology UK Zhengyi Yang EMBL Heidelberg Germany Ellen Zhong Princeton University USA Virtual speaker Scientific Organisers Tanmay Bharat MRC Laboratory of Molecular Biology UK Sebastian Eustermann EMBL Heidelberg Germany Julia Mahamid EMBL Heidelberg Germany Simone Mattei EMBL Heidelberg Germany Lori Passmore MRC Laboratory of Molecular Biology UK Conference Organisers Ellen Malovrh EMBL Heidelberg Germany Irena Provaznikova Scientific Training Manager EMBL Heidelberg Germany Aline Cecilie Schnieder Course and Conference Manager EMBL Heidelberg Germany Programme Are you on social media Post using EMBOCryoEM and don t forget to tag EMBLEvents Some pre course work such as watching pre recordings protocol reading and computational exercises with estimated time 0 10 hours will be required and will be shared in advance of the course Some speakers may need to join virtually to give their lecture or Q A and the programme is subject to change Day 0 Monday 8 July 2024 Time Europe Berlin ProgrammeLocation12 00 13 30Virtual onboarding session and introduction to EMBL e Campus and how to view recorded lecturesVirtual Day 1 Sunday 18 August2024 Time Europe BerlinProgrammeLocation15 00 15 40Registration and refreshmentsISG Hotel15 40 15 50Introduction and housenote slidesSebastian Eustermann EMBL Heidelberg GermanyISG Hotel15 50 16 00Course overviewISG Hotel16 00 17 00Student flash talksISG Hotel17 00 17 30Coffee breakISG Hotel17 30 18 30Student flash talksISG Hotel18 30 19 45Remote Lecture 1 Past and future of cryoEMRobert Glaeser Lawrence Berkeley National Laboratory USA virtual speaker ISG Hotel19 45 20 45DinnerISG Hotel Day 2 Monday 19 August 2024 Time Europe BerlinProgrammeLocation08 40 08 45Overview of the dayCourtyard Rooms08 45 09 05Industry talk Automation in cryo EM workflowsMaximilian Gemmer Thermo Fisher ScientificCourtyard Rooms09 05 10 20Lecture Cryo EM image formation and opticsChris Russo MRC Laboratory of Molecular Biology UKCourtyard Rooms10 20 10 50Coffee breakkindly sponsored by DECTRISCourtyard Rooms10 50 12 05Lecture Next generation microscope hardware Carsten Sachse Forschungszentrum J lich Germany Courtyard Rooms12 05 13 05Lunch breakEMBL Canteen13 05 14 20Remote Lecture Next generation cryoEM single particle sample preparation acquisitionKelly Nguyen MRC Laboratory of Molecular Biology UKCourtyard Rooms14 20 15 35Lecture cryoET sample preparation acquisitionJulia Mahamid EMBL Heidelberg GermanyCourtyard Rooms15 35 16 05Coffee breakkindly sponsored by DECTRISCourtyard Rooms16 05 17 20Remote Lecture Fundamentals in image processing Maximum likelihoodSjors Scheres MRC Laboratory of Molecular Biology UKCourtyard Rooms17 20 18 35EMBO Young Investigator Lecture Fundamentals in image processing cryoETTanmay Bharat MRC Laboratory of Molecular Biology UKCourtyard Rooms18 35 19 35DinnerEMBL Canteen Day 3 Tuesday 20 August 2024 Time Europe BerlinProgrammeLocation08 40 08 45Overview of the dayCourtyard Rooms08 45 09 05Industry talkAndrew Smith Kleindiek Nanotechnik GermanyCourtyard Rooms09 05 10 20Next generation High resolution by cryo ET subtomogram averagingDimitry Tegunov Genentech USACourtyard Rooms10 20 10 40Coffee breakkindly sponsored by DECTRISCourtyard Rooms10 40 11 55Next generation 2D template matching and beyondNikolaus Grigorieff University of Massachusetts Medical School USACourtyard Rooms11 55 12 25Panel discussion Hardware and sample preparationPanel leaders Simone Mattei and Julia Mahamid EMBL Heidelberg GermanyCourtyard Rooms12 25 13 25Lunch breakEMBL Canteen13 25 15 55Practical session ASession 1 on Advanced cryoEM single particle analysis RelionSPA topicSebastian Eustermann EMBL Heidelberg GermanySession 2 on Advanced cryoEM single particle analysis cyroSPARC SPA topicHui Guo Max Planck Institute of Biochemistry GermanySession 3 on Advanced cryoET subtomogram averaging Relion Tomo topicTanmay Bharat MRC Laboratory of Molecular Biology UK Andriko von K gelgen MRC Laboratory of Molecular Biology UK Session 4 on Advanced cryoET subtomogram averaging WARP M Tomo topicDimitry Tegunov Genentech USAJoe Dobbs EMBL Heidelberg GermanyRasmus Kjeldsen Jensen EMBL Heidelberg GermanySession 5 on Model building refinement and validationColin Palmer UKRI STFC UKSession 1 Courtyard Rooms Session 2 Flex Lab BSession3 Flex Lab ASession 4 Computer Training LabSession 5 Helix Seminar Room B15 55 16 25Coffee breakkindly sponsored by DECTRISCourtyard Rooms16 25 18 55Practical session BSession 1 on Advanced cryoEM single particle analysis RelionSPA topic cont Sebastian Eustermann EMBL Heidelberg GermanySession 2 on Advanced cryoEM single particle analysis cyroSPARC SPA topic cont Hui Guo Max Planck Institute of Biochemistry GermanySession 3 on Advanced cryoET subtomogram averaging Relion Tomo topic cont Tanmay Bharat MRC Laboratory of Molecular Biology UK Andriko von K gelgen MRC Laboratory of Molecular Biology UKSession 4 on Advanced cryoET subtomogram averaging WARP M Tomo topic cont Dimitry Tegunov Genentech USAJoe Dobbs EMBL Heidelberg GermanyRasmus Kjeldsen Jensen EMBL Heidelberg GermanySession 5 on Model building refinement and validation cont Colin Palmer UKRI STFC UKSession 1 Courtyard Rooms Session 2 Flex Lab BSession3 Flex Lab ASession 4 Computer Training LabSession 5 Helix Seminar Room B18 55 19 55Canteen dinnerEMBL Canteen19 55 20 55Remote Lecture Hot topics recent breakthroughs and emerging technologiesBridget Carragher Chan Zuckerberg Imaging Institute USA Courtyard Rooms20 55 21 25Discussion round Hot topics recent breakthroughs and emerging technologiesCourtyard Rooms Day 4 Wednesday 21 August 2024 Time Europe BerlinProgrammeLocation09 00 09 05Overview of the dayCourtyard Rooms09 05 10 20Remote Lecture Advances in cryoET particle identificationBeata Turonova Max Planck Institute of Biophysics GermanyCourtyard Rooms10 20 10 40Coffee breakkindly sponsored by SubAngstromCourtyard Rooms10 40 11 55Lecture AI based methods Molecular heterogeneity landscapes from cryoEM and cryoETRishwanth Raghu Princeton University USACourtyard Rooms11 55 12 55Technology Lunch Complete CryoEM SolutionsMark Ebrahim SubAngstrom USARooftop Lounge12 55 13 25Panel discussion Software and image processingPanel leaders Sebastian Eustermann EMBL Heidelberg Germany and Tanmay Bharat MRC Laboratory of Molecular Biology UKCourtyard Rooms13 25 15 55Practical session CSession 1 on Advanced cryoEM single particle analysis RelionSPA topic cont Sebastian Eustermann EMBL Heidelberg GermanySession 2 on Advanced cryoEM single particle analysis cyroSPARC SPA topic cont Hui Guo Max Planck Institute of Biochemistry GermanySession 3 on Advanced cryoET subtomogram averaging Relion Tomo topic cont Tanmay Bharat MRC Laboratory of Molecular Biology UK Andriko von K gelgen MRC Laboratory of Molecular Biology UK Session 4 on Advanced cryoET subtomogram averaging WARP M Tomo topic cont Dimitry Tegunov Genentech USASession 5 on Model building refinement and validation cont Colin Palmer UKRI STFC UKSession 1 Courtyard Rooms Session 2 Flex Lab BSession3 Flex Lab ASession 4 Computer Training LabSession 5 Helix Seminar Room B15 55 16 25Coffee breakkindly sponsored by SubAngstromCourtyard Rooms16 25 18 55Practical session DSession 1 on Advanced cryoEM single particle analysis RelionSPA topic cont Sebastian Eustermann EMBL Heidelberg GermanySession 2 on Advanced cryoEM single particle analysis cyroSPARC SPA topic cont Hui Guo Max Planck Institute of Biochemistry GermanySession 3 on Advanced cryoET subtomogram averaging Relion Tomo topic cont Tanmay Bharat MRC Laboratory of Molecular Biology UK Andriko von K gelgen MRC Laboratory of Molecular Biology UK Session 4 on Advanced cryoET subtomogram averaging WARP M Tomo topic cont Dimitry Tegunov Genentech USAJoe Dobbs EMBL Heidelberg GermanySession 5 on Model building refinement and validation cont Colin Palmer UKRI STFC UKSession 1 Courtyard Rooms Session 2 Flex Lab BSession3 Flex Lab ASession 4 Computer Training LabSession 5 Helix Seminar Room B18 55 19 55Pizza dinnerHelix B19 55 20 55Poster session with drinks 12 posters Helix B Day 5 Thursday 22 August 2024 Time Europe BerlinProgrammeLocation09 00 09 05Overview of the dayCourtyard Rooms09 05 10 05Lecture Next generation Atomic model building refinement and validationSebastian Eustermann EMBL Heidelberg GermanyCourtyard Rooms10 05 11 05Lecture Next generation integrative model buildingJan Kosinski EMBL Hamburg GermanyCourtyard Rooms11 05 11 35Coffee breakkindly sponsored by CEOS GmbHCourtyard Rooms11 35 12 35EMDB and EMPIAR Data repositoriesKyle Morris EMBL EBI UKCourtyard Rooms12 35 13 05Panel discussion Validation and FAIR dataPanel leader Lori Passmore MRC Laboratory of Molecular Biology UK and Sebastian Eustermann EMBL Heidelberg GermanyCourtyard Rooms13 05 14 05Technology Lunch Can aberration correctors help in cryo electron microscopy Heiko M ller CEOS Germany Rooftop Lounge14 05 16 35Practical session ESession 1 on Advanced cryoEM single particle analysis RelionSPA topic cont Sebastian Eustermann EMBL Heidelberg GermanySession 2 on Advanced cryoEM single particle analysis cyroSPARC SPA topic cont Hui Guo Max Planck Institute of Biochemistry GermanySession 3 on Advanced cryoET subtomogram averaging Relion Tomo topic cont Tanmay Bharat MRC Laboratory of Molecular Biology UK Andriko von K gelgen MRC Laboratory of Molecular Biology UK Session 4 on Advanced cryoET subtomogram averaging WARP M Tomo topic cont Dimitry Tegunov Genentech USAJoe Dobbs EMBL Heidelberg GermanyRasmus Kjeldsen Jensen EMBL Heidelberg GermanySession 5 on Model building refinement and validation cont Colin Palmer UKRI STFC UKSession 6 on Macromolecular Heterogeneity Analysis cryoDRGN topic cont Ryan Feathers Princeton University USARishwanth Raghu Princeton University USASession 7 2D template matching cont Nikolaus Grigorieff University of Massachusetts Medical School USASession 1 Courtyard Rooms Session 2 Flex Lab BSession3 Flex Lab ASession 4 Computer Training LabSession 5 Helix Seminar Room BSession 6 B11 Session 7 B2816 35 17 05Coffee breakkindly sponsored by CEOS GmbHCourtyard Rooms17 05 19 35Practical session FSession 1 on Advanced cryoEM single particle analysis RelionSPA topic cont Sebastian Eustermann EMBL Heidelberg GermanySession 2 on Advanced cryoEM single particle analysis cyroSPARC SPA topic cont Hui Guo Max Planck Institute of Biochemistry GermanySession 3 on Advanced cryoET subtomogram averaging Relion Tomo topic cont Tanmay Bharat MRC Laboratory of Molecular Biology UK Andriko von K gelgen MRC Laboratory of Molecular Biology UK Session 4 on Advanced cryoET subtomogram averaging WARP M Tomo topic cont Dimitry Tegunov Genentech USAJoe Dobbs EMBL Heidelberg GermanyRasmus Kjeldsen Jensen EMBL Heidelberg GermanySession 5 on Model building refinement and validation cont Colin Palmer UKRI STFC UKSession 6 on Macromolecular Heterogeneity Analysis cryoDRGN topicRyan Feathers Princeton University USARishwanth Raghu Princeton University USASession 7 2D template matchingNikolaus Grigorieff University of Massachusetts Medical School USAJohannes Elferich University of Massachusetts Medical School USASession 1 Courtyard Rooms Session 2 Flex Lab BSession3 Flex Lab ASession 4 Computer Training LabSession 5 Helix Seminar Room BSession 6 B11 Session 7 B2819 35 20 35DinnerEMBL Canteen20 35 21 35Poster session with drinks 12 posters Helix B Day 6 Friday 23 August 2024 Time Europe BerlinProgrammeLocation09 00 09 05Overview of the dayCourtyard Rooms09 05 10 20High Throughput and Resolution Data collectionSimone Mattei EMBL Heidelberg GermanyCourtyard Rooms10 20 11 35Correlative light and electron microscopy for Structural Cell BiologyWanda Kukulski University of Bern SwitzerlandCourtyard Rooms11 35 11 55Coffee breakkindly sponsored by SubAngstromCourtyard Rooms11 55 12 25Panel discussion Data acquisitionPanel leader Simone Mattei EMBL Heidelberg GermanyCourtyard Rooms12 25 13 25Lunch breakEMBL Canteen13 25 15 55Practical Session GSession 1 on Advanced cryoEM single particle analysis RelionSPA topic cont Sebastian Eustermann EMBL Heidelberg GermanySession 2 on Advanced cryoEM single particle analysis cyroSPARC SPA topic cont Hui Guo Max Planck Institute of Biochemistry GermanySession 3 on Advanced cryoET subtomogram averaging Relion Tomo topic cont Tanmay Bharat MRC Laboratory of Molecular Biology UK Andriko von K gelgen MRC Laboratory of Molecular Biology UK Session 4 on Advanced cryoET subtomogram averaging WARP M Tomo topic cont Dimitry Tegunov Genentech USAAlister Burt Genentech USAJoe Dobbs EMBL Heidelberg GermanyRasmus Kjeldsen Jensen EMBL Heidelberg GermanySession 5 on Model building refinement and validation cont Colin Palmer UKRI STFC UKSession 6 on Macromolecular Heterogeneity Analysis cryoDRGN topic cont Ryan Feathers Princeton University USARishwanth Raghu Princeton University USASession 7 2D template matching cont Nikolaus Grigorieff University of Massachusetts Medical School USAJohannes Elferich University of Massachusetts Medical School USASession 1 Courtyard Rooms Session 2 Flex Lab BSession3 Flex Lab ASession 4 Computer Training LabSession 5 Helix Seminar Room BSession 6 B11 Session 7 B2815 55 16 25Coffee breakkindly sponsored by SubAngstromCourtyard Rooms16 25 18 55Practical Session HSession 1 on Advanced cryoEM single particle analysis RelionSPA topic cont Sebastian Eustermann EMBL Heidelberg GermanySession 2 on Advanced cryoEM single particle analysis cyroSPARC SPA topic cont Hui Guo Max Planck Institute of Biochemistry GermanySession 3 on Advanced cryoET subtomogram averaging Relion Tomo topic cont Tanmay Bharat MRC Laboratory of Molecular Biology UK Andriko von K gelgen MRC Laboratory of Molecular Biology UK Session 4 on Advanced cryoET subtomogram averaging WARP M Tomo topic cont Dimitry Tegunov Genentech USAAlister Burt Genentech USAJoe Dobbs EMBL Heidelberg GermanyRasmus Kjeldsen Jensen EMBL Heidelberg GermanySession 5 on Model building refinement Colin Palmer UKRI STFC UKSession 6 on Macromolecular Heterogeneity Analysis cryoDRGN topic cont Ryan Feathers Princeton University USARishwanth Raghu Princeton University USASession 7 2D template matching cont Nikolaus Grigorieff University of Massachusetts Medical School USAJohannes Elferich University of Massachusetts Medical School USASession 1 Courtyard Rooms Session 2 Flex Lab BSession3 Flex Lab ASession 4 Computer Training LabSession 5 Helix Seminar Room BSession 6 B11 Session 7 B2818 55 19 55Dinner in EMBL CanteenEMBL Canteen19 55 20 25Lecture cryoEM careers in academia and pharmaDimitry Tegunov Genentech USACourtyard Rooms20 25 21 25Discussion round Career pathsCourtyard Rooms Day 7 Saturday 24 August 2024 Time Europe BerlinProgrammeLocation10 00 10 05Overview of the dayCourtyard Rooms10 05 12 05Practical Session I Drop in sessionSession 1 on Advanced cryoEM single particle analysis RelionSPA topic cont Sebastian Eustermann EMBL Heidelberg GermanySession 2 on Advanced cryoEM single particle analysis cyroSPARC SPA topic cont Hui Guo Max Planck Institute of Biochemistry GermanySession 3 on Advanced cryoET subtomogram averaging Relion Tomo topic cont Tanmay Bharat MRC Laboratory of Molecular Biology UK Andriko von K gelgen MRC Laboratory of Molecular Biology UK Session 4 on Advanced cryoET subtomogram averaging WARP M Tomo topic cont Dimitry Tegunov Genentech USAAlister Burt Genentech USAJoe Dobbs EMBL Heidelberg GermanyRasmus Kjeldsen Jensen EMBL Heidelberg GermanySession 6 on Macromolecular Heterogeneity Analysis cryoDRGN topic cont Ryan Feathers Princeton University USARishwanth Raghu Princeton University USASession 7 2D template matching cont Nikolaus Grigorieff University of Massachusetts Medical School USAJohannes Elferich University of Massachusetts Medical School USASession 8 on Cryo TEMSimon Fromm EMBL Heidelberg GermanySession 9 on Cryo LMZhengyi Yang EMBL Heidelberg GermanySession 10 on HPF Waffle prepAnna Steyer EMBL Heidelberg GermanySession 11 on FIB SEMHigor Rosa EMBL Heidelberg GermanySession 1 Courtyard Rooms Session 2 Flex Lab BSession3 Flex Lab ASession 4 Computer Training LabSession 5 Helix Seminar Room BSession 6 B11 Session 7 B28Session 8 9 10 Imaging Center12 05 13 05Lunch breakEMBL Canteen13 05 15 05Practical Session J Drop in sessionSession 1 on Advanced cryoEM single particle analysis RelionSPA topic cont Sebastian Eustermann EMBL Heidelberg GermanySession 2 on Advanced cryoEM single particle analysis cyroSPARC SPA topic cont Hui Guo Max Planck Institute of Biochemistry GermanySession 3 on Advanced cryoET subtomogram averaging Relion Tomo topic cont Tanmay Bharat MRC Laboratory of Molecular Biology UK Andriko von K gelgen MRC Laboratory of Molecular Biology UK Session 4 on Advanced cryoET subtomogram averaging WARP M Tomo topic cont Dimitry Tegunov Genentech USAAlister Burt Genentech USAJoe Dobbs EMBL Heidelberg GermanyRasmus Kjeldsen Jensen EMBL Heidelberg GermanySession 5 on Model building refinement and validation cont Sebastian Eustermann EMBL Heidelberg GermanySession 6 on Macromolecular Heterogeneity Analysis cryoDRGN topic cont Ryan Feathers Princeton University USARishwanth Raghu Princeton University USASession 7 2D template matching cont Nikolaus Grigorieff University of Massachusetts Medical School USAJohannes Elferich University of Massachusetts Medical School USASession 8 on Cryo TEMSimon Fromm EMBL Heidelberg GermanySession 9 on Cryo LMZhengyi Yang EMBL Heidelberg GermanySession 10 on HPF Waffle prepAnna Steyer EMBL Heidelberg GermanySession 11 on FIB SEMHigor Rosa EMBL Heidelberg GermanySession 1 Courtyard Rooms Session 2 Flex Lab BSession3 Flex Lab ASession 4 Computer Training LabSession 5 Helix Seminar Room BSession 6 B11 Session 7 B28Session 8 9 10 Imaging Center15 05 15 25Coffee breakCourtyard Rooms15 25 17 25Practical Session K Drop in sessionSession 1 on Advanced cryoEM single particle analysis RelionSPA topic cont Sebastian Eustermann EMBL Heidelberg GermanySession 2 on Advanced cryoEM single particle analysis cyroSPARC SPA topic cont Hui Guo Max Planck Institute of Biochemistry GermanySession 3 on Advanced cryoET subtomogram averaging Relion Tomo topic cont Tanmay Bharat MRC Laboratory of Molecular Biology UK Andriko von K gelgen MRC Laboratory of Molecular Biology UK Session 4 on Advanced cryoET subtomogram averaging WARP M Tomo topic cont Dimitry Tegunov Genentech USAAlister Burt Genentech USAJoe Dobbs EMBL Heidelberg GermanyRasmus Kjeldsen Jensen EMBL Heidelberg GermanySession 5 on Model building refinement and validation cont Sebastian Eustermann EMBL Heidelberg GermanySession 6 on Macromolecular Heterogeneity Analysis cryoDRGN topic cont Ryan Feathers Princeton University USARishwanth Raghu Princeton University USASession 7 2D template matching cont Nikolaus Grigorieff University of Massachusetts Medical School USAJohannes Elferich University of Massachusetts Medical School USASession 8 on Cryo TEMSimon Fromm EMBL Heidelberg GermanySession 9 on Cryo LMZhengyi Yang EMBL Heidelberg GermanySession 10 on HPF Waffle prepAnna Steyer EMBL Heidelberg GermanySession 11 on FIB SEMHigor Rosa EMBL Heidelberg GermanySession 1 Courtyard Rooms Session 2 Flex Lab BSession3 Flex Lab ASession 4 Computer Training LabSession 5 Helix Seminar Room BSession 6 B11 Session 7 B28Session 8 9 10 Imaging Center17 25 19 25Free time downtown19 25 21 25Dinner in city centre Day 8 Sunday 25 August 2024 Time Europe BerlinProgrammeLocation10 00 10 05Overview of the dayCourtyard Rooms10 05 12 05Practical Session L Drop in sessionSession 1 on Advanced cryoEM single particle analysis RelionSPA topic cont Sebastian Eustermann EMBL Heidelberg GermanySession 2 on Advanced cryoEM single particle analysis cyroSPARC SPA topic cont Hui Guo Max Planck Institute of Biochemistry GermanySession 3 on Advanced cryoET subtomogram averaging Relion Tomo topic cont Tanmay Bharat MRC Laboratory of Molecular Biology UK Andriko von K gelgen MRC Laboratory of Molecular Biology UK Session 4 on Advanced cryoET subtomogram averaging WARP M Tomo topic cont Dimitry Tegunov Genentech USAAlister Burt Genentech USAJoe Dobbs EMBL Heidelberg GermanyRasmus Kjeldsen Jensen EMBL Heidelberg GermanySession 5 on Model building refinement and validation cont Sebastian Eustermann EMBL Heidelberg GermanySession 6 on Macromolecular Heterogeneity Analysis cryoDRGN topic cont Ryan Feathers Princeton University USARishwanth Raghu Princeton University USASession 7 2D template matching cont Nikolaus Grigorieff University of Massachusetts Medical School USAJohannes Elferich University of Massachusetts Medical School USASession 8 on Cryo TEMSimon Fromm EMBL Heidelberg GermanySession 9 on Cryo LMZhengyi Yang EMBL Heidelberg GermanySession 10 on HPF Waffle prepAnna Steyer EMBL Heidelberg GermanySession 11 on FIB SEMHigor Rosa EMBL Heidelberg GermanySession 1 Courtyard Rooms Session 2 Flex Lab BSession3 Flex Lab ASession 4 Computer Training LabSession 5 Helix Seminar Room BSession 6 B11 Session 7 B28Session 8 9 Imaging Center12 05 13 05Lunch breakEMBL Canteen13 05 15 05Practical Session M Drop in sessionSession 1 on Advanced cryoEM single particle analysis RelionSPA topic cont Sebastian Eustermann EMBL Heidelberg GermanySession 2 on Advanced cryoEM single particle analysis cyroSPARC SPA topic cont Hui Guo Max Planck Institute of Biochemistry GermanySession 3 on Advanced cryoET subtomogram averaging Relion Tomo topic cont Tanmay Bharat MRC Laboratory of Molecular Biology UK Andriko von K gelgen MRC Laboratory of Molecular Biology UK Session 4 on Advanced cryoET subtomogram averaging WARP M Tomo topic cont Dimitry Tegunov Genentech USAAlister Burt Genentech USAJoe Dobbs EMBL Heidelberg GermanyRasmus Kjeldsen Jensen EMBL GermanySession 5 on Model building refinement and validation cont Sebastian Eustermann EMBL Heidelberg GermanySession 6 on Macromolecular Heterogeneity Analysis cryoDRGN topic cont Ryan Feathers Princeton University USARishwanth Raghu Princeton University USASession 7 2D template matching cont Nikolaus Grigorieff University of Massachusetts Medical School USAJohannes Elferich University of Massachusetts Medical School USASession 8 on Cryo TEMSimon Fromm EMBL Heidelberg GermanySession 9 on Cryo LMZhengyi Yang EMBL Heidelberg GermanySession 10 on HPF Waffle prepAnna Steyer EMBL Heidelberg GermanySession 11 on FIB SEMHigor Rosa EMBL Heidelberg GermanySession 1 Courtyard Rooms Session 2 Flex Lab BSession3 Flex Lab ASession 4 Computer Training LabSession 5 Helix Seminar Room BSession 6 B11 Session 7 B28Session 8 9 Imaging Center15 05 15 35Coffee breakCourtyard Rooms15 35 17 35Practical Session N Drop in sessionSession 1 on Advanced cryoEM single particle analysis RelionSPA topic cont Sebastian Eustermann EMBL Heidelberg GermanySession 2 on Advanced cryoEM single particle analysis cyroSPARC SPA topic cont Hui Guo Max Planck Institute of Biochemistry GermanySession 3 on Advanced cryoET subtomogram averaging Relion Tomo topic cont Tanmay Bharat MRC Laboratory of Molecular Biology UK Andriko von K gelgen MRC Laboratory of Molecular Biology UK Session 4 on Advanced cryoET subtomogram averaging WARP M Tomo topic cont Dimitry Tegunov Genentech USAAlister Burt Genentech USAJoe Dobbs EMBL Heidelberg GermanyRasmus Kjeldsen Jensen EMBL Heidelberg GermanySession 5 on Model building refinement and validation cont Sebastian Eustermann EMBL Heidelberg GermanySession 6 on Macromolecular Heterogeneity Analysis cryoDRGN topic cont Ryan Feathers Princeton University USARishwanth Raghu Princeton University USASession 7 2D template matching cont Nikolaus Grigorieff University of Massachusetts Medical School USAJohannes Elferich University of Massachusetts Medical School USASession 8 on Cryo TEMSimon Fromm EMBL Heidelberg GermanySession 9 on Cryo LMZhengyi Yang EMBL Heidelberg GermanySession 10 on HPF Waffle prepAnna Steyer EMBL Heidelberg GermanySession 11 on FIB SEMHigor Rosa EMBL Heidelberg GermanySession 1 Courtyard Rooms Session 2 Flex Lab BSession3 Flex Lab ASession 4 Computer Training LabSession 5 Helix Seminar Room BSession 6 B11 Session 7 B28Session 8 9 Imaging Center17 35 18 50Poster sessionHelix B18 50 19 50Canteen dinnerEMBL Canteen19 50 20 00Bus to ISG hotelATC Entrance20 00 21 00Lecture Future of cell structural biologyJulia Mahamid EMBL Heidelberg GermanyISG Hotel Day 9 Monday 26 August 2024 Time Europe BerlinProgrammeLocation08 40 08 45Overview of the dayCourtyard Rooms08 45 09 45Lecture Hot topics recent breakthroughs and emerging technologies in structural biology via cryoETSvetlana Dodonova EMBL Heidelberg GermanyCourtyard Rooms09 45 10 45Lecture Hot topics recent breakthroughs and emerging technologies in structural biology via cryoEMCristina Paulino Heidelberg University GermanyCourtyard Rooms10 45 11 15Coffee breakCourtyard Rooms11 15 12 15Wrap up practicals highlights presented by participantsCourtyard Rooms12 15 13 15Final panel discussion Wrap up with emphasis on the future of cryoEM responsible practice reporting and validation standardsCourtyard Rooms13 15 13 30Packed lunch and departureATC Entrance Practical information Registration fees and motivation letter The course is limited to up to 24 participants For selection purposes please note that your application will not be considered without a letter of motivation Registration Registration fees include admission course materials COVID 19 safety measures meals and coffee breaks This EMBO course includes accommodation and transportation to and from the ISG Hotel to the venue Academia 500PhD Student 500Industry 1000 Confirmation and payment The registration fee should be paid only after acceptance to the course The results will be announced approximately 2 3 weeks after the application deadline Motivation letter submission After you have logged in and successfully registered you will receive an email asking you to submit your motivation letter Click on the link provided and enter your motivation letter in the text box provided Alternatively you can submit your motivation letter by clicking on the link on the confirmation page directly after registering Instructions Include your relevant skills experience and qualifications showing why you would be suitable for the course Explain why you would like to attend including what you can contribute and how you think you will benefit from the course Please note The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised For more detailed information follow the instructions provided in our video on how to submit a course motivation letter Further details For further information about registration and motivation letter submission please refer to the FAQ page Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of both registration fee waivers and travel grants Availability is limited to participants attending on site events in Heidelberg and will be indicated during the abstract or motivation letter submission process Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course or conference Travel grant The travel grant will cover the cost of travel airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Course EMBL Conference or EMBO EMBL Symposium from within Europe up to 1000 for participants travelling to an EMBL Course EMBL Conference or EMBO EMBL Symposium from outside Europe up to 500 for any participant travelling to an EMBO Practical Course or EMBO Workshop up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Practical Course or EMBO Workshop Registration fees are only covered for EMBO Practical Courses or EMBO WorkshopsThe organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant EMBO practical courses and workshops only For EMBO Practical Course or EMBO Workshop participants with children there is the possibility to apply for a childcare grant to offset child care costs incurred by participants or speakers when participating at a course or conference Eligible costs include fees for a baby sitter or child care facility travel costs for a care giver or travel costs for taking the child to the meeting etc Please note that priority will be given to early stage researchers A maximum amount of 500 EUR can be awarded per participant applying for an EMBO Childcare Grant In order to apply for this grant for EMBO Workshops you must be registered by the abstract submission deadline Application You may apply for financial assistance when submitting your motivation letter for courses and abstract for conferences In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application For the Boehringer Ingelheim Fonds Travel Grant there is a pre application question during the motivation letter submission process and if selected you will be requested to complete a standard form and documentation consisting of your travel expense estimation Selection The scientific organisers will select the recipients of all financial assistance during the motivation letter or abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection is based on your current work or study location the reasons for needing financial support and the impact this event will have on your career Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details View our list of external funding opportunities and information on attending a conference as an event reporter For further information about financial assistance please refer to the FAQ page Accommodation and travel Hotel Accommodation in twin rooms including breakfast is included in the registration fee Accommodation has been booked for you at the ISG Hotel for the default dates of 18 to 26 8 nights In case you would like to have a single room please let the hotel know and please note that you will be required to pay an additional cost of 32 per night availability of single rooms may be limited This should be paid by you directly to the ISG during your stay Any additional nights need to be booked and paid for by you We recommend that all course participants stay at the ISG Hotel which is the dedicated hotel for the course Travel information For travel information please see here If you are travelling to the conference within Germany then you are eligible for the Deutsche Bahn Event Ticket called the Veranstaltungsticket in German This will result in a lower ticket price if your travel distance to Heidelberg is more than 100 km You need to provide proof of your event attendance when purchasing the ticket For more information in English see here or in German see here You can book your ticket here Local transport Shuttle buses will go from the ISG Hotel to EMBL and back mornings and evenings A bus schedule and location of the bus stops will be made available prior to the meeting Further details Address EMBL Heidelberg Meyerhofstra e 1 69117 Heidelberg GermanyFor more information about accommodation and travel please refer to the FAQ page On site information Catering All meals and coffee breaks are included in the registration fee Our catering staff will prepare a wide variety of vegetarian meals meat and fish dishes soups pasta fresh fruit and vegetables as well as a variety of desserts Please wear your badge at all times when serving yourself No food or drinks are allowed in the laboratories Electricity and charging station In most places the electricity is 220 volts AC 50 cycles An adaptor and a plug that fits the German socket may be needed for your appliances laptop i e American Japanese etc A USB charging station for electronic devices is available at the registration desk EMBL Merchandise If you are interested in purchasing EMBL merchandise products presented in the glass display in the registration area please email the EMBL shop to place an order or get in contact with your Course Organiser Kindly note the EMBL shop is only open upon request and all purchases must be made in cash Euros only Health and safety notes Please read EMBL s COVID 19 safety policy for on site events Do not smoke in any EMBL building Eating and drinking is prohibited in all laboratories Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required The first aid room is located next to the ATC Registration Desk room 10 205 Dial the Emergency number 222 from any EMBL internal phone only Where is the accident What happened How many injured Emergency number 06221 387 7821 from mobile phones Please report all accidents to the conference officer at the registration desk In case of fire Press the nearest fire alarm button or the Emergency number 222 from any internal phone A loud fire alarm will go off if an evacuation is required On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting points Do not use the lifts Beyond first aid Please remember to bring your own medication if needed to the conference Note that the next pharmacy is a 4 minute drive from the EMBL but for many medications you will be required to see a doctor to get a prescription Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg In any case the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary Internet Wi Fi is available on campus Log in using the EMBL Events network and the event specific password which will be provided on site The eduroam network secure worldwide roaming access service developed for the international research and education community is also available Lost and found Lost and Found items are kept at the registration desk until the end of the conference Luggage There are lockers available on site to store your luggage which require a 2 EURO coin to operate There is another luggage room on level E0 which is free to use but remains unlocked during the conference Nursing room There is a nursing room available in the ATC Rooftop Lounge on level A29 Photography During the conference an EMBL Photographer may be taking photos If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Printing We can help to print your boarding pass train ticket Please send it to events embl de and collect your print outs at the registration desk Room for prayer yoga and meditation There is a room for prayer meditation and yoga located on level E0 behind the Auditorium Please be respectful of others using the room Sightseeing A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing Travel to and from the venue During the event we provide conference shuttle buses to and from EMBL In addition there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time Information on the shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page Map to walk from ISG Hotel to EMBL Additional information Address EMBL Heidelberg Meyerhofstra e 1 69117 Heidelberg Germany ATC orientation map Please find additional information including FAQs terms and conditions COVID 19 Technical requirements and event software Event software The EMBL eCampus learning platform will be used to collaborate communicate and network with all of the course participants All participants will receive information on how to join shortly before the course We recommend using Chrome Safari or Mozilla Firefox browsers for eCampus Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page COVID 19 related questions COVID 19 information for on site events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Media partners Imaging and Microscopy a Wiley magazine Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9...

Julia Mahamid, Sebastian Eustermann, Simone Mattei, Lori Passmore, Henning Stahlberg

EMBO Practical Course

EMBL Heidelberg

15 July - 19 July 2024

Proteomics bioinformatics

Edit

July 15, 2024 00:002024CourseEMBL-EBI

Description Thank you to those of you who have applied we have now selected our participants and wait list There are no more spaces available You can however register your interest for the 2025 course here This course provides hands on training in the basics of mass spectrometry MS and proteomics bioinformatics You will receive training on how to use search engines and post processing software quantitative approaches MS data repositories the use of public databases for protein analysis annotation of subsequent protein lists and incorporation of information from molecular interaction and pathway databases The practical elements of the course will take raw data from a proteomics experiment and analyse it You will be able to go from MS spectra to identifying and quantifying peptides and finally to obtaining lists of protein identifiers that can be analysed further using a wide range of resources The final aim is to provide you with the practical bioinformatics knowledge you need to go back to the lab and process your own data when collected This course is organised in association with the Vlaams Instituut voor Biotechnologie VIB the Flemish Institute for Biotechnology Pre recorded material may be provided before the course starts that you will need to watch read or work through to gain the most out of the actual training event In person courseThe course fee is inclusive of four nights of accommodation and catering including dinner We plan to deliver this course in person onsite at our training suite at EMBL EBI Hinxton Please be aware that we are continually evaluating the ongoing pandemic situation and as such may need to change the format of courses at short notice Your safety is paramount to us you can read our COVID guidance policy for more information All information is correct at time of publishing...

Barbara Etzi

EMBL-EBI

8 July - 9 July 2024

Edit

July 04, 2024 00:002024CourseOther

Description The one day browser workshop offers participants the possibility of gaining lots of hands on experience in the use of the Ensembl genome browser but also provides them with the necessary background information The workshop is primarily targeted at wetlab researchers The workshop will consist of a series of modules listed in the content Most modules consist of a presentation and a demonstration of the tools followed by the opportunity to do exercises Participants are encouraged to bring problems questions about their research and we will try to tackle these during the workshop using Ensembl...

Marco Aurelio Cristancho Ardila

Other

1 July - 5 July 2024

Bioinformatics for immunologists

Edit

July 01, 2024 00:002024CourseEMBL-EBI

Description This course will provide participants with an introduction to a range of bioinformatics resources and approaches applicable to immunological research Participants will gain experience in analysis pipelines for NGS experiments relevant to immunology including immune receptor sequencing RNA sequencing single cell RNA sequencing and flow cytometry data analysis Additionally participants will be introduced to how data from several sources can be integrated to provide a wider view of their research thereby enabling them to be more confident users of their own data and that from public sources...

Juanita Riveros

EMBL-EBI

26 June 2024

Data visualisation principles for enhancing effective scientific communication

Edit

June 26, 2024 15:302024WebinarVirtual

Description This webinar will provide an introduction to data visualisation principles It includes a review of basic concepts and showcases tools to improve your understanding and use of data visualisation for improved accessibility to your research As we know collecting data is just the first step to advancing scientific knowledge Data presentation techniques are the key to communicating your findings in a concise manner to improve understanding across audiences and ultimately strengthening your contributions to your field The webinar speaker Isabel Romero Calvo PhD MS Scientific Illustrator will present information that will help you gain insights into Gestalt principlesConcept of salience and graphic perceptionUse of colour in data visualisationAccessibility in data visualisationWe will conclude with a Q A session for the webinar attendees...

Virtual

24 June - 28 June 2024

Cancer genomics and transcriptomics

Edit

June 24, 2024 00:002024CourseVirtual

Description This course will focus on the analysis of data from genomic studies of cancer It will also highlight the application of transcriptomic analysis and single cell technologies in cancer Talks and interactive sessions will give an insight into the bioinformatic concepts required to analyse such data whilst practical sessions will enable the participants to apply statistical methods to the analysis of cancer genomics data under the guidance of the trainers Virtual courseParticipants will learn via a mix of pre recorded lectures live presentations and trainer Q A sessions Practical experience will be developed through group activities and trainer led computational exercises Live sessions will be delivered using Zoom with additional support and asynchronous communication via Slack Pre recorded material may be provided before the course starts that participants will need to watch read or work through to gain the most out of the actual training event In the week before the course there will be a brief induction session Computational practicals will run on EMBL EBI s virtual training infrastructure meaning participants will not require access to a powerful computer or install complex software on their own machines Participants will need to be available between the hours of 08 45 17 00 BST each day of the course Trainers will be available to assist answer questions and provide further explanations during these times...

Meredith Willmott

Virtual

18 June - 21 June 2024

Innate immunity in host-pathogen interactions

Edit

June 18, 2024 00:002024ConferenceEMBL Heidelberg, Virtual

Description OverviewSpeakersProgrammePractical informationSponsorsAboutMedia kit Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Symposium overview This follow up meeting to the successful EMBO EMBL Symposia Innate immunity in Host Pathogen Interactions in 2016 2018 and 2022 will provide a discussion and networking platform for all scientists interested in the biology of pathogen infection The symposium will promote the exchange of conceptual ideas in this rapidly evolving field and also foster cross disciplinary collaborations among the scientists Innate immunity is studied by both microbiologists and immunologists however their perspectives differ widely Microbiologists are necessarily specialists for their pathogen s of choice while immunologists tend to focus on the host response The goal of the conference is to bring together immunologists microbiologists and cell biologists who from their specific points of view will discuss recent progress in their understanding of host pathogen interactions The conference will have a balanced representation of viruses bacteria fungi and for the first time parasites as the major classes of medically relevant animal or economically important plant pathogens A unique aspect of the meeting will be the holistic approach of discussing host pathogen interactions also across phylogenetically distant hosts i e plants and animals Session topics Sensing pathogens The cell biology of infection Signaling upon pathogen detection Cell autonomous immunity Pathogen countermeasures Pathological consequences of infection and inflammation What past participants say about the Symposium This conference is exceptionally good and was my first conference at EMBL Various topics of innate immune response has been covered in this conference which further broaden my knowledge in the field of host pathogen interaction s Very well organised and good networking opportunity for the people in the field of immunology and microbiology Sanpreet Singh CSIR IMTech India As my first international symposium the EMBO EMBL Symposium Innate Immunity in Host Pathogen Interactions was inspiring great fun and facilitated both scientific exchange and networking It was great to present my PhD work to a very engaged audience featuring many major names in my field Looking forward to next time Conor O Donovan MRC LMB Cambridge UK This conference is the best of its kind in bringing together researchers who work in hostpathogen interactions The format was great and the conference was exceptionally wellorganized Cynthia Guo University of Toronto Canada Speakers Keynote speakers Vishva Dixit Genentech USA Dominique Soldati Favre University of Geneva Switzerland Speakers Aude Bernheim Institut Pasteur France Jelena Bezbradica Mirkovic Kennedy Institute of Rheumatology UK Gordon Brown University of Exeter UK Ken Cadwell University of Pennsylvania USA Rachael Dangarembizi University of Cape Town South Africa Della David Babraham Institute UK Trude Helen Flo Norwegian University of Science and Technology Norway Michaela Gack Cleveland Clinic Foundation USA Veit Hornung Ludwig Maximilians Universit t M nchen Germany Bernhard Hube Leibniz Institute for Natural Product Research and Infection Biology Hans Kn ll Institute Germany Jonathan Jones The Sainsbury Laboratory UK Marc Lecuit Institut Pasteur France Jonathan Pruneda Oregon Health Science University USA John Schoggins The University of Texas Southwestern Medical Center USA Wai Hong Tham Walter and Eliza Hall Institute of Medical Research Australia Julia Vorholt ETH Z rich Switzerland Sho Yamasaki Research Institute for Microbial Diseases Japan Jian Min Zhou Yazhouwan National Laboratory China Scientific organisers Gordon Brown University of Exeter UK Michaela Gack Cleveland Clinic Foundation USA Felix Randow MRC Laboratory of Molecular Biology UK Dominique Soldati Favre University of Geneva Switzerland Cyril Zipfel University of Z rich Switzerland Conference organisers Iva Gavran EMBL Heidelberg Germany Programme Are you on social media Post using EESImmunity and don t forget to tag EMBLEvents Please note that the programme is subject to change Some speakers may need to join virtually to give their talk For registered participants recorded talks will be accessible on demand for 2 weeks after the end of the event unless indicated otherwise Day 1 Tuesday 18 June 2024 Time Europe Berlin Speaker12 00 13 30Registration and light refreshments13 30 13 45Opening remarks13 45 14 45Keynote talk Toxplasma gondii a persisting challengeDominique Soldati Favre University of Geneva Switzerland14 45 18 15Session 1 Sensing pathogensTrude Flo Norwegian University of Science and Technology Norway14 45 15 15Immune responses to mycobacterial lipidsSho Yamasaki Research Institute for Microbial Diseases JapanNot available on demand15 15 15 30Recognition of phylogenetically diverse pathogens through enzymatically amplified recruitment of RNF213Ana Crespillo Casado MRC Laboratory of Molecular Biology UK15 30 15 45Immune recognition of structured phage RNA by bacterial cGASDalton Banh Rockefeller University USA15 45 16 15Coffee Break and Meet the speakers with Dominique Soldati Favre and Sho Yamasaki16 15 16 45Understanding and exploiting plant immune receptor mechanismsJonathan Jones The Sainsbury Laboratory UK16 45 17 00ADAR1 haploinsufficiency and viral RdRp dsRNA synthesis synergize to dysregulate RNA editing and cause multi system interferonopathyEric Poeschla University of Colorado School of Medicine USA 17 00 17 15The epigenetic reader SP140 participates in a host virus nuclear arms race by regulating inteferon beta mRNA stability via RESISTRussel Vance HHMI University of California Berkeley USA17 15 18 15Speed networking session18 15 19 45BBQ dinner19 45 21 30After dinner drinks in ATC Rooftop lounge Day 2 Wednesday 19 June 2024 Time Europe Berlin Speaker09 00 12 00Session 2 The cell biology of infectionChair Cyril Zipfel University of Z rich Switzerland09 00 09 30M tuberculosis induced cell death and a new macrophage alveolar epithelial cell co culture modelTrude Flo Norwegian University of Science and Technology NorwayNot available on demand09 30 09 45The macrophage endoplasmic reticulum protein VAPA participates in the salvage of host lipids by Leishmania amazonensisAlbert Descoteaux Institut national de la recherche scientifique Canada09 45 10 00Nucleotide Based Defense Strategies in Bacterial Antiviral ImmunityNitzan Tal Weizmann Institute of Science Israel10 00 10 30Coffee Break and Meet the speakers with Jonathan Jones and Trude Flo10 30 11 00Nanobodies that block malaria parasite transmissionWai Hong Tham Walter and Eliza Hall Institute of Medical Research Australia11 00 11 15The role of fungal cell wall in predation by immune cells and bacteriaAgate Auzane University of Exeter UK11 15 11 45A functional screen for ubiquitin regulation identifies an E3 ligase secreted by Pseudomonas aeruginosaJonathan Pruneda Oregon Health Science University USA11 45 12 00Keep an eye on both sides Host membrane microdomains are required for Mycobacterium marinum induced membrane damage and infectionThierry Soldati University of Geneva Switzerland12 00 13 30Lunch and Meet the Editors 30min at the end of lunch 13 30 16 30Session 3 Signaling upon pathogen detectionChair Chair Michaela Gack Cleveland Clinic Foundation USA13 30 14 00Harnessing C elegans pathogen response to mitigate protein aggregationDella David Babraham Institute UK14 00 14 15A host AAA ATPase employs chemo mechanical force to exhibit bacteriolytic activitySourav Ghosh Indian Institute of Technology Bombay India14 15 14 30Deciphering oligomerization effects on plant receptor activity in innate immunityZhiming Ma Nanyang Technological University Singapore14 30 14 45 Discovery of a novel actor of the TLR4 pathway using comparative immunology across domains of lifeHugo Vaysset Institut Pasteur FranceNot available on demand14 45 15 15Coffee Break and Meet the speakers with Wai Hong Tam Jonathan Pruneda and Della David15 15 15 45CLRs Autoimmunity and immunity to fungal infection a new link Gordon Brown University of Exeter UK15 45 16 00Identification and characterization of plant cytokinesJack Rhodes The Sainsbury Laboratory UK16 00 16 30Intersection of plant immunity and microbiota homeostasisJulia Vorholt ETH Z rich Switzerland16 30 17 15Flash talks 55 57 61 63 77 83 85 87 115 131 133 137 15717 15 19 15Poster Session 1 odd numbers with beer and snacks19 15Free evening Day 3 Thursday 20 June 2024 Time Europe Berlin Speaker09 00 12 00Session 4 Cell autonomous immunityChair Felix Randow MRC Laboratory of Molecular Biology UK09 00 09 30TRIMming autophagic antiviral host defensesMichaela Gack Cleveland Clinic Foundation USANot available on demand09 30 09 45Metabolic enzymes moonlight as selective autophagy receptors to protect plants against viral induced cellular damageMarion Clavel Max Planck Institute of Molecular Plant Physiology Germany09 45 10 00How cytosolic bacteria inhibit RNF213 mediated cell autonomous immunityMagdalena Szczesna Imperial College London UK10 00 10 30Coffee Break and Meet the speakers with Gordon Brown Julia Vorholt and Michaela Gack10 30 11 00Membrane channels as facilitators of immune cell cross talk in infection and inflammationJelena Bezbradica Mirkovic Kennedy Institute of Rheumatology UK11 00 11 15Metabolism infection and inflammation the immunometabolic interplay of salmonella persistence in macrophagesMatthew Eldridge Harvard Medical School USA11 15 11 45Evolution of anti viral immunity across domains of lifeAude Bernheim Institut Pasteur France11 45 12 00Evolution guided enhancement of MxA antiviral properties against influenza virusRechel Geiger Fred Hutch Cancer Center USA12 00 13 30Lunch 13 30 16 30Session 5 Pathogen countermeasuresChair Dominique Soldati Favre University of Geneva Switzerland13 30 14 00New models of interferon mediated antiviral immunityJohn Schoggins The University of Texas Southwestern Medical Center USA14 00 14 15Targeted degradation of host messenger RNA by a bacterial effector modulates macrophage metabolismKitty McCaffrey Hudson Institute of Medical Research AustraliaNot available on demand14 15 14 30The bacterial effector SteD reduces surface levels of MHCII by activating the E3 ubiquitin ligase WWP2Samkeliso Blundell Imperial College London UK14 30 15 00Coffee Break and Meet the speakers with Jelena Bezbradica Mirkovic Aude Bernheim and John Schoggins15 00 15 30The commensal training ground of Candida albicansBernhard Hube Leibniz Institute for Natural Product Research and Infection Biology Hans Kn ll Institute Germany15 30 15 45Direct antimicrobial functions of HMGB1 and countermeasures deployed by Gram negative bacteriaJeannette Messer Cleveland Clinic USA15 45 16 15Understanding immune signaling and chemical defense against phytopathogenic bacteriaJian Min Zhou Yazhouwan National Laboratory ChinaNot available on demand16 15 16 30Activation and Evasion of the FACT ETS 1 Antiviral Response Pathway by RNA VirusesEmily Rex University of Texas Southwestern Medical Center USA16 30 16 45Flash talks 52 56 84 8616 45 18 45Poster Session 2 even numbers with beer and snacks18 45 20 30Dinner in the canteen20 30 23 30Conference party with live music Day 4 Friday 21 June 2024 Time Europe Berlin Speaker09 30 13 45Session 6 Pathological consequences of infection and inflammationChair Gordon Brown University of Exeter UK09 30 10 00How Listeria outsmarts the hostMarc Lecuit Institut Pasteur FranceNot available on demand10 00 10 15The contribution of the innate immune response to blood brain barrier breakdown in Cerebral MalariaAlina Batzilla EMBL Barcelona Spain10 15 10 45The counterintuitive innate neuroimmune response to cryptococcal infectionRachael Dangarembizi University of Cape Town South Africa10 45 11 15Coffee Break and Meet the speakers with Bernhard Hube Jian Min Zhou Marc Lecuit Rachael Dangarembizi Ken Cadwell Veit Hornung and Vishva Dixit11 15 11 45Autophagy at the host microbe interfaceKen Cadwell University of Pennsylvania USA11 45 12 00Brain endothelial GSDMD activation mediates inflammatory BBB breakdownWei Jiang National Institute of Biological Sciences China12 00 12 30Detection of non self nucleic acids in the endolysosomeVeit Hornung Ludwig Maximilians Universit t M nchen GermanyNot available on demand12 30 13 30Why so many ways to die Vishva Dixit Genentech USA13 30 13 45Closing Remarks and Poster Prize Announcements13 45 14 15Packed Lunch and departure14 15Bus to airport tickets available at registration desk 14 30Conference shuttle Practical information Registration fees and abstract submission On site registration fees include admission conference materials meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Virtual registration fees include access to all of the talks livestreamed and on demand and facility to submit questions On site Academia 725On site PhD Student 625On site Industry 925On site Journal Editors 300Virtual Academia 225Virtual PhD Student 175Virtual Industry 275 Editors from scientific journals are allowed to attend at a reduced rate but asked to contribute to the conference in return by taking part in meet the editors sessions or other planned activities within the programme A letter to support your visa application will be issued on request once payment of the registration fee is confirmed We recommend that you book your visa appointment as soon as possible to avoid any delay with your visa application Accredited journalists may be eligible to register for complimentary press registration Registrants may be required to provide accreditation or equivalent proof of press membership after registration Please contact Iva Gavran for more information Please note that we do not offer complimentary registrations for editors of scientific journals Confirmation and payment Registration will be on a first come first served basis Your place can only be confirmed after payment of the registration fee If you are added to our waiting list please consider taking advantage of our offerings to participate virtually On site participants Types of payments accepted are international bank transfers and credit card payments Virtual participants We are only able to accept card payments In exceptional cases we can accept bank transfers Please contact events embl de for details Abstract submission Only participants registering to attend the on site event are eligible to submit an abstract Abstracts will not be accepted from virtual participants After registration you can submit your abstract via a separate link that will be provided in the email confirmation Alternatively you can access the link on the confirmation page directly after registering The same login credentials are used for both processes Please note Abstract body The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised Title The title should not exceed 20 words Only the first word of the title should start with a capital letter and the rest should be lowercase Authors and affiliations Please fill in the author s details as requested in the online form The compulsory fields are First Name Last Name Organisation Name Affiliation or Company Country and Email Kindly mark only one author in the role of First Author and please don t forget to indicate who will be the Presenter Please enter your co authors correctly via the system by adding accounts together with their organisation institute Do not copy paste them into the body of the abstract text as they will not be indexed in the abstract book Presentation types When submitting your abstract you can apply for an oral or poster presentation A selection process will take place with the results announced 2 3 weeks after the abstract submission deadline For detailed instructions on how to submit a conference abstract follow the instructions provided in this video Please check our FAQs pages for further information on how to submit an abstract Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of registration fee waivers travel grants and childcare grants Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course or conference Travel grant The travel grant will cover the cost of travel to an on site event airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from within Europe up to 1000 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from outside Europe up to 500 for any participant travelling to an EMBO Workshop up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Workshop up to 700 for any participant working in Croatia Czech Republic Estonia Greece Hungary Italy Lithuania Luxembourg Poland Slovenia and Turkey travelling to an EMBO Workshop Registration fees are only covered for EMBO Workshops The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant There is the possibility to apply for a childcare grant to offset child care costs incurred by participants speakers and organisers when attending a conference Eligible costs include but are not limited to fees for a baby sitter or child care facility and travel costs for a caregiver Please note that priority will be given to early stage researchers In order to apply for this grant you must be registered by the abstract submission deadline There is a limited amount of funding available for the childcare grants and funds will be distributed amongst eligible applicants Application On site participants You may apply for financial assistance when submitting your abstract In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Virtual participants If you are attending virtually you can apply for financial assistance in the submission portal by the abstract deadline Read the instructions on how to apply for financial assistance Only submissions for financial assistance will be accepted Presentation abstracts cannot be submitted here and will be declined In your application you will be asked to summarise your current work answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Selection The scientific organisers will select the recipients of all financial assistance during the abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details View our list of external funding opportunities and information on attending a conference as an event reporter For further information about financial assistance please refer to the FAQ page Accommodation and travel Accommodation is not included in the conference registration fee The hotels below have rooms on hold for participants until 21 May 2024 in some cases at special rates Please email the hotel directly quoting the booking code EES24 08 to confirm the exact price of the room Hotel AnlageHotel ibis HeidelbergPremier Inn Heidelberg CityHotel Bayrischer Hof ISG Hotel Staycity Aparthotel HeidelbergB B HotelLeonardo Hotel Heidelberg City CentreSteffi s Hostel HeidelbergExzellenz HotelMeininger HeidelbergHotel Vier Jahreszeiten HeidelbergHotel Holl nder Hof Hotel MonptiHilton Heidelberg Travel information For travel information please see here If you are travelling to the conference within Germany then you are eligible for the Deutsche Bahn Event Ticket called the Veranstaltungsticket in German This will result in a lower ticket price if your travel distance to Heidelberg is more than 100 km You need to provide proof of your event attendance when purchasing the ticket For more information in English see here or in German see here You can book your ticket here Conference shuttle buses Conference shuttle buses are free of charge for participants and depart from designated bus stops near the hotels to EMBL and back mornings and evenings Conference shuttle bus schedule Shuttle bus stops please see Google map with the stops below The bus stops for this conference are Staycity Aparthotel Speyerer Str 7 Kurf rsten Anlage Opposite Main Train Station Premier Inn Kurf rsten Anlage 23 Leonardo Hotel Heidelberg City Center Bergheimer Str 63 Neckarm nzplatz Heidelberg Tourist Information Peterskirche Bus stop ISG Hotel Im Eichwald 19 View Conference shuttle bus stops and hotels in a larger map Please note that not every bus stop will be used for every event Further details Address EMBL Meyerhofstra e 1 69117 Heidelberg Germany For more information about accommodation and travel please refer to the FAQ page On site information Catering All meals and coffee breaks are included in the registration fee Our catering staff will prepare a wide variety of vegetarian meals meat and fish dishes soups pasta fresh fruit and vegetables as well as a variety of desserts Please wear your badge at all times when serving yourself No food or drinks are allowed in the auditorium Charging lockers There are lockers available next to the stairs leading down into the Auditorium You will find some of those equipped with sockets to charge your smartphone tablet etc Electricity and charging station In most places the electricity is 220 volts AC 50 cycles An adaptor and a plug that fits the German socket may be needed for your appliances laptop i e American Japanese etc A USB charging station for electronic devices is available at the registration desk EMBL merchandise If you are interested in purchasing EMBL merchandise products presented in the glass display in the registration area please email the EMBL shop to place an order or get in contact with your Course Organiser Kindly note the EMBL shop is only open upon request and all purchases must be made in cash Euros only Health and safety notes Do not smoke in any EMBL building Eating and drinking is prohibited in the Auditorium and all laboratories Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required The first aid room is located next to the ATC Registration Desk room 10 205 Dial the Emergency number 222 from any EMBL internal phone only Where is the accident What happened How many injured Emergency number 06221 387 7821 from mobile phones Please report all accidents to the conference officer at the registration desk In case of fire Press the nearest fire alarm button or the Emergency number 222 from any internal phone A loud fire alarm will go off if an evacuation is required On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting points Do not use the lifts Beyond first aid Please remember to bring your own medication if needed to the conference Note that the next pharmacy is a 4 minute drive from the EMBL but for many medications you will be required to see a doctor to get a prescription Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg In any case the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary Internet Wi Fi is available on campus using the EMBL Events network and the event specific password which will be provided on site The eduroam network secure worldwide roaming access service developed for the international research and education community is also available Lost and found Lost and Found items are kept at the registration desk until the end of the conference Luggage There are lockers available on site to store your luggage which require a 2 EURO coin to operate There is another luggage room on level E0 which is free to use but remains unlocked during the conference Nursing room There is a nursing room available in the ATC Rooftop Lounge on level A29 Photography During the conference an EMBL Photographer may be taking photos If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Printing We can help to print your boarding pass train ticket Please send it to events embl de and collect your print outs at the registration desk Room for prayer yoga and meditation There is a room for prayer meditation and yoga located on level E0 behind the Auditorium Please be respectful of others using the room Sightseeing A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing Travel to and from the venue During the event we provide conference shuttle buses to and from EMBL In addition there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time Information on the conference shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page Useful German expressions HelloHalloGoodbyeAuf Wiedersehen formal Tsch ss informal Good morningGuten MorgenGood afternoonGuten TagGood eveningGuten AbendGood nightGute NachtI m sorryTut mir leidExcuse me Entschuldigen SieHow are you Wie gehts I m fine thanks And you Mir geht es gut danke Und dir Ihnen What is your nameWie hei en Sie formal Wie hei t du informal My name is Ich hei e Do you speak English Sprechen Sie Englisch I don t understandIch verstehe nichtPlease speak more slowlyK nnen Sie bitte langsamer sprechenThank youDankesch nWhere is the toilet Wo ist die Toilette Please call me a taxiBitte rufen Sie mir ein TaxiHow do I get to Wie komme ich zum zur A beer two beers pleaseEin Bier zwei Bier bitteA glass of red white wine pleaseEin Glas Rot Weisswein bitteThe menu pleaseDie Speisekarte bitteIs there a local speciality Gibt es eine Spezialit t aus dieser Gegend I m VegetarianIch bin VegetarierIt was deliciousEs war hervorragendThe bill pleaseDie Rechnung bitteI have a headacheIch habe KopfschmerzenI have a sore throatIch habe HalsschmerzenMy stomach hurtsIch habe MagenschmerzenI m allergic toIch bin allergisch gegenI need a doctor who speaks EnglishGibt es einen Arzt der Englisch spricht Virtual participation What s included Access to all the livestreamed talks Video library of the recorded talks during the event and for two weeks afterwards Please note at the request of individual speakers some talks are not recorded Facility to submit questions Please note that only on site participants are able to submit abstracts and participate in the poster sessions Event platform We are using an event platform for this conference More information about the platform will be shared ahead of the conference Guidelines Do not broadcast the conference to unregistered participants You are encouraged to tweet and post about the event Tweet unless the speaker specifically says otherwise but be mindful of unpublished data Please do not capture transmit or redistribute data presented at the meeting Additional information can be found in our Code of Conduct Health and well being It is important to stay healthy and move around especially when you are attending an event virtually We have put together a few coffee break stretches and yoga videos in the conference platform for you to enjoy during the event How to ask questions Please use the Q A function in the event platform If you have any other questions you can go to the Help Desk in the event platform Click on more on the top menu and click Help Desk Time zone The programme is planned based on the Europe Berlin time zone unless otherwise stated Please take your time zone into consideration when planning your attendance Additional information Please find additional information including FAQs terms and conditions and travelling to EMBL on our Information for participants page Sponsors Event sponsor ABclonal Germany Disease Models Mechanisms The Company of Biologists InvivoGen MedChemExpress Event supporters Media partners EMBO Reports an EMBO Press journal FEBS Journal FEBS Letters International Union of Biochemistry and Molecular Biology Medinformatics a Bon View Publishing journal Open Biology a Royal Society journal PLOS Biology a PLOS journal Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de About EMBO EMBL Symposia promote scientific communication and collaboration in the European research area They provide scientists with a platform to discuss and exchange ideas on forward looking topics and new developments in the life sciences Topics emphasise upcoming developments and the interdisciplinary nature of related fields Jointly funded and organised by EMBO and EMBL and complementary to their respective courses workshops and conference programmes the symposia promote scientific communication and collaboration All symposia are held in the EMBL Advanced Training Centre ATC in Heidelberg Germany or virtually Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9 Leaderboard 728 90...

Gordon Brown, Michaela Gack, Felix Randow, Dominique Soldati-Favre, Cyril Zipfel

EMBO | EMBL Symposium

EMBL Heidelberg, Virtual

17 June - 21 June 2024

Summer school in bioinformatics

Edit

June 17, 2024 00:002024CourseEMBL-EBI

Description This course provides an introduction to the use of bioinformatics in biological research giving you guidance for using bioinformatics in your work whilst also providing hands on training in tools and resources appropriate to your research You will initially be introduced to bioinformatics theory and practice including best practices for undertaking bioinformatics analysis data management and reproducibility You will be required to review some pre recorded material for their group project prior to the start of the course Group projectsA major element of this course is a group project where you ll be placed in small groups to work together on a challenge set by trainers from EMBL EBI and external institutes This allows you to explore the bioinformatics tools and resources available in your area of interest and apply them to a set problem providing you with hands on experience relevant to your own research The group work will culminate in a presentation session involving everyone on the final day of the course giving an opportunity for wider discussion on the benefits and challenges of working with biological data Groups are mentored and supported by the trainers who set the initial challenge but the groups will be responsible for driving their projects forward with all members expected to take an active role Groups are pre organised before the course and all group members will be sent some short homework in preparation for your project work prior to the start of the course Basic outlines of the projects on offer this year are given below In your application you must indicate your first and second choice of project based on which you think would benefit your research most Not all projects may be offered and final decisions on which projects will be run during the course will be made based on the number of applicants per project Most of the projects cover mammalian data sets however in many cases the methods and approaches taught are transferable to data from various species Group project one Genome variation across human populations Natural variation between individuals or between different human populations is a result of genome mutations throughout evolutionary history Some mutations may become fixed because of their beneficial effect while most drift among individuals During this project you will investigate genomic variation between two separate human populations of European and Asian descent Using sequence data from a number of individuals from each population you will use a range of bioinformatics tools to discover variants that exist between them In the second section of the project you will attempt to analyse the functional consequences of the variants you have identified attempting to find clinical association and linking them to phenotypes Project mentor Anu Shivalikanjli EMBL EBI Group project two Interpreting functional information from large scale protein structure dataThis project will introduce you to the wealth of publicly available data in the Protein Data Bank PDB and give you the opportunity to investigate how large subsets of structure data can be used to analyse protein features and determine function In the project you will learn how to identify relevant protein structures collate and interpret functional information and implement this process programmatically Project mentor Marcus Bage EMBL EBI and Joseph Ellaway EMBL EBIGroup project three Modelling cell signalling pathwaysCurating models of biological processes is an effective training in computational systems biology where the curators gain an integrative knowledge of biological systems modelling and bioinformatics You will learn to encode and simulate ordinary differential equation models of signalling pathways from a recent publication using user friendly software such as COPASI even without extensive mathematical background You will learn to perform in silico experiments new predictions and develop hypotheses Furthermore you will learn how to annotate models and re use pre existing models from open repositories such as BioModels Project mentors Rahuman Sheriff EMBL EBI and Krishna Tiwari EMBL EBI Group project four Improving AI based bioimage analysis Artificial Intelligence AI algorithms outperform classical image analysis methods however the performance of these models is highly dependent on the quality of the annotated image datasets used to train them In this project you will explore the application of AI for biological imaging and the relationship between model training data and model performance You will use models stored in the BioImage Model Zoo and data in the BioImage Archive to fine tune and aggregate AI outputs The aim of this project will be to test evaluate and improve model performance on a diverse set of microscopy images and annotations within the BioImage Archive You will learn how to apply train tune and employ the most performant state of the art computer vision models This project serves as a valuable demonstration of how FAIR Findable Accessible Interoperable Reusable data plays an essential role in the training and enhancement of AI models Project mentors Aybuke Kupcu Yoldas EMBL EBI and Craig Russel EMBL EBI Group project five Single cell RNA sequencing analysis with PythonIn this project you will learn how to perform single cell RNA sequencing data analysis to investigate cell type heterogeneity and expression differences across conditions The analysis will be based on the SCANPY framework in Python You will start by collecting the raw count matrix and relevant metadata from the Single cell Expression Atlas After constructing the AnnData objects you will perform quality control preprocessing dimensionality reduction cell type annotation and differential expression analysis We will also explore the batch effect and its correction Project mentors Yuyao Song EMBL EBI and Anna Vathrakokoili Pournara EMBL EBI Group project six Networks and pathwaysThis project will cover typical bioinformatics analysis steps needed to put differentially expressed genes into a wider biological context You will start with gene expression data RNA seq to build an initial interaction network Next you will learn to combine public network datasets identify key regulators of biological pathways and explore biological function through network analysis You will get first hand experience in integration and co visualising with additional data and functional enrichment analysis All this helps to put the initial results into a previously known context and provide hypotheses for potential follow up experiments We will use Cytoscape Expression Atlas g Profiler StringDb among other tools We may also give a few R packages a try Project mentor Priit Adler University of Tartu...

Barbara Etzi

EMBL-EBI

10 June - 14 June 2024

Systems biology: from large datasets to biological insight

Edit

June 10, 2024 00:002024CourseEMBL-EBI

Description This course covers the use of computational tools to extract biological insight from omics datasets The content will explore a range of approaches ranging from network inference and data integration to machine learning and logic modelling that can be used to extract biological insights from varied data types Together these techniques will provide participants with a useful toolkit for designing new strategies to extract relevant information and understanding from large scale biological data The motivation for running this course is a result of advances in computer science and high performance computing that have led to groundbreaking developments in systems biology model inference With the comparable increase of publicly available large scale biological data the challenge now lies in interpreting them in a biologically valuable manner Likewise machine learning approaches are making a significant impact in our analysis of large omics datasets and the extraction of useful biological knowledge...

Juanita Riveros

EMBL-EBI

9 June - 15 June 2024

C. elegans: from genome editing to imaging

Edit

June 09, 2024 00:002024CourseEMBL Heidelberg

Description OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview Course overview C elegans is a popular experimental model that combines transparency reproducible anatomy traceable cell lineage sequenced genome and facile genetics allowing to dissect animal development physiology and behaviour across scales of genes cells and tissues This 7 day course will present experimental practices in C elegans research while introducing historic and up to date findings in various research topics Each day includes lectures practicals student poster presentations and interactive discussions with faculty Various methodologies commonly employed in C elegans research will be presented in parallel practicals with rotating student groups by relevant experts These experimental techniques span forward and reverse genetics genome editing lineaging imaging approaches for live and fixed samples using light and electron microscopy computational image analysis and other useful web resources Meanwhile lectures by internationally established researchers will present a variety of C elegans research topics spanning studies of the genome and epigenome through cell cycle and death to tissue specification connectivity and function A combination of senior and junior speakers will ensure a balanced view of pioneer breakthroughs and recent advances in the topics presented as well as the students interactions with researchers of different topics and career levels Audience This practical course will be aimed at early career scientists mostly postdocs and advanced graduate students with an interest in C elegans We will target both participants with little or no prior experience in working with C elegans who want to use this model organism to advance their research as well as experienced C elegans researchers who want to expand their tool set The course will cover state of the art techniques that are or will become essential for a broad range of research topics and we will therefore target participants with diverse research interests Modules resources The course lectures and practical modules develop in three axes of genes cells tissues It will cover the following modules Lectures Genome and epigenome structure function silencing environment interactions Cell cycle division symmetry breaking cell biomechanics Cell death and degeneration in development aging and genome instability in disease Tissue specification transcriptome dynamics morphogenesis Tissue morphogenesis cell lineage tracing and forces Tissue assembly connectivity activity cell interactions Practicals Web resources for C elegans research C elegans handling and genetic manipulations Imaging fixed live cells and molecules Image analysis deconvolution EM image analysis optogenetics tracing and lineaging approaches Learning outcomes After this course you should know The advantages of C elegans for your research Handling and maintenance of C elegans Staging and C elegans life cycle Designing and performing forward and reverse genetics experiments Principles of generating transgenic animals The potential of C elegans imaging from live imaging to high resolution imaging EM and optogenetics Options for analysis of light and EM images optogenetics cell tracing What past participants say about the course The c elegans from genome editing to imaging is one of the best C elegans practical courses and I would strongly recommend C elegans researchers in their early careers to attend this course Somarani Dash Institute of advanced study in science and technology Guwahati Assam India This course far exceeded my expectations it was the perfect mixture of theory hands onexperiments and networking An incredible opportunity not only to learn but also to meet peoplefrom all over the world Antonella Lavatellai Centre for Research in Agricultural Genomics Barcelona Spain The course has a recommendation rate of 100 from previous attendees Please see EMBL s COVID 19 safety recommendations for testing and other requirements to attend this on site course This event has been granted the following EMBO sustainability badge Grade 2 of 3 Speakers Speakers trainers and staff Michalis Barkoulas Imperial College UK Virtual Speaker Simon Berger University of Zurich Switzerland Virtual Speaker Mandy Boermel EMBL Heidelberg Germany Ed Boyden MIT McGovern Institute USA Virtual Speaker Henrik Bringmann Biotechnology Center Germany Inka Busack Biotechnology Center Germany Francesca Caroti EMBL Heidelberg Germany Dhanya K Cheerambathur The University of Edinburgh UK Monica Driscoll Rutgers University USA Virtual Speaker Marie Anne Felix Institut Biologie Ecole Normale Superieure France Christian Fr kj r Jensen King Abdullah University Saudi Arabia Susan Gasser University of Lausanne and ISREC Foundation Switzerland Guoye Guan Peking University China Virtual Trainer Alex Hajnal University of Zurich Switzerland Virtual Speaker Oliver Hobert Columbia University USA Virtual Speaker Simone K hler EMBL Heidelberg Germany Marko Lampe EMBL Heidelberg Germany Zelin Li University of Hong Kong Hong Kong Virtual trainer Yangning Lu MIT McGovern Institute USA Rachel Mellwig EMBL Heidelberg Germany Ben Mulcahy Lunenfeld Tanenbaum Research Institute Canada Virtual trainer Alexandre Paix Max Planck Institute for Biology T bingen Germany Cristina Pineiro Lopez EMBL Heidelberg Germany Georgia Rapti EMBL Heidelberg Germany Suzan Ruijtenberg Utrecht University The Netherlands Piali Sengupta Brandeis University USA Virtual Speaker Pavak Shah University of California Los Angeles USA Priya Sivaramakrishnan Children s Hospital of Philadelphia USA Virtual trainer Johanna Tocci EMBL Heidelberg Germany Zhongying Zhao Hong Kong Baptist University Hong Kong Scientific organisers Henrik Bringmann Biotechnology Center Germany Simone K hler EMBL Heidelberg Germany Georgia Rapti EMBL Heidelberg Germany Pavak Shah University of California Los Angeles USA Event organisers Maria Bacadare Course and Conference Team Lead EMBL Heidelberg Germany Swetlana Krez Training Lab Technician EMBL Heidelberg Germany Programme Are you on social media Post using EMBOCelegans and don t forget to tag EMBLEvents Some pre course work such as watching pre recordings protocol reading and computational exercises with estimated time 0 10 hours will be required and will be shared in advance of the course Some speakers may need to join virtually to give their lecture or Q A and the programme is subject to change Day 0 Onboarding Monday 27 May 2024 Time Europe Berlin SpeakerLocation15 30 17 00Onboarding session access to eCampus learning platform introduction on Zoom introduction to the course materials to be used and expectations from the participants overview of the tools used during the courseEMBL eCampus Day 1 Sunday 9 June 2024 Time Europe Berlin SpeakerLocation09 45 10 00Bus from hotel to EMBL ATC EntranceISG Hotel bus stop10 00 10 30Health and safety briefingCourtyard Room A B10 30 13 30Optional Bootcamp A or BOption A Basic C elegans methodology maintenance propagation decontaminationTrainers Simone K hler EMBL Heidelberg GermanyGeorgia Rapti EMBL Heidelberg GermanyCristina Pi eiro L pez EMBL Heidelberg GermanyFrancesca Caroti EMBL Heidelberg GermanyOption B Basic principles for image analysisTrainer Pavak Shah University of California Los Angeles USATraining LabComputer Training LabCourtyard Room13 30 14 30Lunch EMBL Canteen14 30 14 45Bus from EMBL ATC Entrance to hotel ATC Entrance15 00 15 30ISG Hotel registrationISG Hotel15 30 15 45WelcomeSimone K hler EMBL Heidelberg GermanyGeorgia Rapti EMBL Heidelberg GermanyISG Hotel15 45 16 15Flash talks 1 min per participant ISG Hotel16 15 17 15Challenges expectations for the course all participants ISG Hotel17 15 17 30Coffee breakISG Hotel17 30 17 45Course overviewSimone K hler EMBL Heidelberg GermanyGeorgia Rapti EMBL Heidelberg GermanyISG Hotel17 45 18 45Introduction to useful web resources and databases for C elegans researchIntroduction on responsible conduct of researchSimone K hler EMBL Heidelberg GermanyGeorgia Rapti EMBL Heidelberg GermanyISG Hotel18 45 19 00BreakISG Hotel19 00 20 00DinnerISG Hotel Day 2 Monday 10 June 2024 Time Europe Berlin SpeakerLocation08 40 08 50Bus to EMBL ATC EntranceISG Hotel bus stop08 55 09 00Overview of the dayCourtyard Room A B09 00 09 30Lecture Imaging the worm nucleus through developmentSusan Gasser University of Lausanne and ISREC Foundation SwitzerlandCourtyard Room A B09 30 09 45Q A after the lectureCourtyard Room A B09 45 10 15Lecture Genome engineeringChristian Fr kj r Jensen King Abdullah University Saudi ArabiaCourtyard Room A B10 15 10 30Q A after the lectureCourtyard Room A B10 30 11 00Coffee breakCourtyard Room A B11 00 11 30Lecture Optogenetic manipulation of tissue activityHenrik Bringmann Biotechnology Center GermanyCourtyard Room A B11 30 11 45Q A after the lectureCourtyard Room A B11 45 12 15Health and safety briefingCourtyard Room A B12 15 13 15Lunch breakEMBL Canteen13 15 19 30Practical Methods of genome manipulation Part 1Station 1 Screening RNAi mutagenesis Trainer Francesca Caroti EMBL Heidelberg Germany Georgia Rapti EMBL Heidelberg Germany Station 2 Transgenesis sample preparation injection Trainer Simone K hler EMBL Heidelberg Germany Cristina Pi eiro L pez EMBL Heidelberg Germany Station 3 Design for CRISPRs MoSCIs arrays Trainer Christian Fr kj r Jensen King Abdullah University Saudi Arabia Alexandre Paix Max Planck Institute for Biology T bingen Germany Station 4 In silico Lineaging Transcriptomics design analysisTrainer Priya Sivaramakrishnan University of Pennsylvania USAStation 1 Training Lab BStation 2 Simone s LabStation 3 Courtyard RoomStation 4 Flex labs19 30 20 30Dinner with guided discussion on Publishing and Grant writing EMBL Canteen20 30Bus to ISG HotelATC Entrance Day 3 Tuesday 11 June 2024 Time Europe Berlin SpeakerLocation08 40 08 55Bus to EMBL ATC EntranceISG Hotel bus stop08 55 09 00Overview of the dayCourtyard Room A B09 00 10 45Practical Methods of genome manipulation Part 1Station 1 Screening RNAi mutagenesis Trainer Francesca Caroti EMBL Heidelberg Germany Georgia Rapti EMBL Heidelberg Germany Station 2 Transgenesis sample preparation injection Trainer Simone K hler EMBL Heidelberg Germany Cristina Pi eiro L pez EMBL Heidelberg Germany Station 3 Design for CRISPRs MoSCIs arrays Trainer Christian Fr kj r Jensen King Abdullah University Saudi Arabia Alexandre Paix Max Planck Institute for Biology T bingen Germany Station 4 In silico Lineaging Transcriptomics design analysisTrainer Priya Sivaramakrishnan University of Pennsylvania USAStation 1 Training Lab BStation 2 Simone s LabStation 3 Courtyard RoomStation 4 Flex labs10 45 11 30Coffee breakCourtyard Room A B11 30 12 00Lecture Cell fate and the cell cycle of the early embryoPavak Shah University of California Los Angeles USACourtyard Room A B12 00 12 15Q A after the lectureCourtyard Room A B12 15 12 45Lecture Expansion microscopy of C elegansEd Boyden MIT McGovern Institute USA Virtual Speaker 12 45 13 00Q A after the lecture13 00 14 00Lunch break with guided discussion on Choosing a postdoc Getting a research PI position EMBL Canteen14 00 17 00Practical Imaging cells and molecules Part 1Station 1 Live imaging and Lineaging Trainer Francesca Caroti EMBL Heidelberg Germany Georgia Rapti EMBL Heidelberg Germany Pavak Shah University of California Los Angeles USA Station 2 Expansion Microscopy Trainer Yangning Lu MIT McGovern Institute USA Simone K hler EMBL Heidelberg Germany Cristina Pi eiro L pez EMBL Heidelberg Germany Station 3 Basics in Optogenetics Trainer Inka Busack Biotechnology Center GermanyStation 4 Electron Microscopy Trainer Mandy Boermel EMBL Heidelberg Germany Rachel Mellwig EMBL Heidelberg Germany Station 1 Microscopy room 116 ALMFStation 2 Training Lab BStation 3 ALMFStation 4 EM facility17 00 17 30Coffee breakCourtyard Room A B17 30 18 00Lecture Cytoskeletal assembly and dynamics in neurodevelopmentDhanya Cheerambathur The University of Edinburgh UKCourtyard Room A B18 00 18 15Q A after the lectureCourtyard Room A B18 15 18 30Coffee breakCourtyard Room A B18 30 19 30Poster session Helix A19 30 21 00Dinner with poster networking All posters Helix A21 00Bus to ISG HotelATC Entrance Day 4 Wednesday 12 June 2024 Time Europe Berlin SpeakerLocation08 40 08 55Bus to EMBL ATC EntranceISG Hotel bus stop08 55 09 00Overview of the dayCourtyard Room A B09 00 09 30Lecture Imaging and understanding translation regulation in development Suzan Ruijtenberg Utrecht University The NetherlandsCourtyard Room A B09 30 09 45Q A after the lectureCourtyard Room A B09 45 10 00Coffee breakCourtyard Room A B10 00 10 30Lecture Genotype to phenotype relationshipMichalis Barkoulas Imperial College UK Virtual Speaker Courtyard Room A B10 30 10 45Q A after the lectureCourtyard Room A B10 45 11 15Lecture Molecular Promotion of Healthy Aging Monica Driscoll Rutgers University USA Virtual Speaker Courtyard Room A B11 15 11 30Q A after the lectureCourtyard Room A B11 30 11 45Group photoCourtyard Room A B11 45 12 30Lunch break with guided discussion on Science policy communication Choosing a postdoc EMBL Canteen12 30 19 00Practical Imaging cells and molecules Part 2 Station 1 Live imaging and Lineaging Trainer Francesca Caroti EMBL Heidelberg Germany Georgia Rapti EMBL Heidelberg GermanyPavak Shah University of California Los Angeles USA Station 2 Expansion Microscopy Trainer Yangning Lu MIT McGovern Institute USA Simone K hler EMBL Heidelberg Germany Cristina Pi eiro L pez EMBL Heidelberg Germany Station 3 Basics in Optogenetics Trainer Inka Busack Biotechnology Center Germany Station 4 Electron Microscopy Trainer Mandy Boermel EMBL Heidelberg Germany Rachel Mellwig EMBL Heidelberg Germany Paolo Ronchi EMBL Heidelberg GermanyStation 1 Microscopy room 116 ALMFStation 2 Training Lab BStation 3 ALMFStation 4 EM facility19 00 20 00DinnerEMBL Canteen20 00Bus to ISG HotelATC Entrance Day 5 Thursday 13 June 2024 Time Europe Berlin SpeakerLocation08 40 08 55Bus to EMBL ATC EntranceISG Hotel bus stop08 55 09 00Overview of the dayCourtyard Room A B09 00 12 00Practical Imaging cells and molecules Part 3 Station 1 Live imaging and Lineaging Trainer Francesca Caroti EMBL Heidelberg Germany Georgia Rapti EMBL Heidelberg Germany Pavak Shah University of California Los Angeles USA Station 2 Expansion Microscopy Trainer Yangning Lu MIT McGovern Institute USASimone K hler EMBL Heidelberg Germany Cristina Pi eiro L pez EMBL Heidelberg Germany Station 3 Basics in Optogenetics Trainer Inka Busack Biotechnology Center GermanyStation 4 Electron Microscopy Trainer Mandy Boermel EMBL Heidelberg Germany Rachel Mellwig EMBL Heidelberg Germany Paolo Ronchi EMBL Heidelberg GermanyStation 1 Microscopy room 116 ALMFStation 2 Training Lab BStation 3 ALMFStation 4 EM facility12 00 13 00Lunch break with guided discussion on Starting a junior PI position Positions in PUI institutions EMBL Canteen13 00 16 00Practical Advanced image analysis tools Station 1 Deconvolution Trainer Marko Lampe EMBL Heidelberg Germany Station 2 Automated membrane tracingTrainer Zhongying Zhao Li Zelin Virtual trainer Guoye Guan Virtual Trainer Station 3 Lineage tracing analysis Trainer Pavak Shah University of California Los Angeles USA Station 4 Image analysis for optogenetics Trainer Inka Busack Biotechnology Center Germany Station 5 Analysis of EM imaging Trainer Ben Mulcahy Lunenfeld Tanenbaum Research Institute CanadaStation 1 Computer Training LabStation 2 Flex Lab A Station 3 Courtyard room Station Station 4 B18 Station Station 5 Flex Lab B16 00 16 30Coffee breakCourtyard Room A B16 30 17 00Lecture Automated high throughput imaging of C elegans Applications and future possibilitiesAlex Hajnal University of Zurich Switzerland Virtual speaker Simon Berger University of Zurich Switzerland Virtual speaker Courtyard Room A B17 00 17 15Meet the speaker Alex Hajnal University of Zurich Switzerland Virtual Speaker Simon Berger University of Zurich Switzerland Virtual speaker Courtyard Room A B17 15 17 45Lecture Neurogenetics of sensory behaviorsPiali Sengupta Brandeis University USA Virtual Speaker Courtyard Room A B17 45 18 00Meet the speaker Piali Sengupta Brandeis University USA Virtual Speaker Courtyard Room A B18 00 18 30Coffee breakCourtyard Room A B18 30 19 00Lecture Self organization in meiosisSimone K hler EMBL Heidelberg GermanyCourtyard Room A B19 00 19 15Meet the speaker Simone K hler EMBL Heidelberg GermanyCourtyard Room A B19 15 20 45Dinner with poster networking All posters Helix A20 45Bus to ISG HotelATC Entrance Day 6 Friday 14 June 2024 Time Europe Berlin SpeakerLocation08 40 08 55Bus to EMBL ATC EntranceISG Hotel bus stop08 55 09 00Overview of the dayCourtyard Room A B09 00 12 00Practical Advanced image analysis tools Station 1 Deconvolution Trainer Marko Lampe EMBL Heidelberg Germany Station 2 Automated membrane tracingTrainers Zhongying Zhao Hong Kong Baptist University Hong KongGuoye Guan Peking University China Virtual trainer Li Zelin University of Hong Kong Hong Kong Virtual trainer Station 3 Lineage tracing analysis Trainer Pavak Shah University of California Los Angeles USA Station 4 Image analysis for optogenetics Trainer Inka Busack Biotechnology Center Germany Station 5 Analysis of EM imaging Trainer Ben Mulcahy Lunenfeld Tanenbaum Research Institute CanadaStation 1 Computer Training Lab Station 2 Flex Lab A Station 3 Courtyard room Station 4 B18 Station 5 Flex Lab B12 00 13 00LunchEMBL Canteen13 00 13 30Lecture Generation of neuronal diversityOliver Hobert Columbia University USA Virtual Speaker Courtyard Room A B13 30 13 45Meet the speaker Oliver Hobert Columbia University USACourtyard Room A B13 45 14 00Coffee breakCourtyard Room A B14 00 16 30Practical Advanced image analysis tools Station 1 Deconvolution Trainer Marko Lampe EMBL Heidelberg Germany Station 2 Automated membrane tracingTrainers Zhongying Zhao Hong Kong Baptist University Hong KongGuoye Guan Peking University China Virtual trainer Li Zelin University of Hong Kong Hong Kong Virtual trainer Station 3 Lineage tracing analysis Trainer Pavak Shah University of California Los Angeles USA Station 4 Image analysis for optogenetics Trainer Inka Busack Biotechnology Center Germany Station 5 Analysis of EM imaging Trainer Ben Mulcahy Lunenfeld Tanenbaum Research Institute CanadaStation 1 Computer Training Lab Station 2 Flex Lab A Station 3 Courtyard room Station 4 B18 Station 5 Flex Lab B16 30 17 00Bus to downtownATC Entrance17 00 19 00Free time19 00Dinner downtown Day 7 Saturday 15 June 2024 Time Europe Berlin SpeakerLocation09 40 09 55Bus to EMBL ATC EntranceISG Hotel bus stop09 55 10 00Overview of the dayCourtyard Room A B10 00 10 30Lecture Evolution of C elegansMarie Anne F lix Institut Biologie Ecole Normale Superieure FranceCourtyard Room A B10 30 10 45Meet the speaker Marie Anne F lix Institut Biologie Ecole Normale Superieure FranceCourtyard Room A B10 45 11 15Coffee breakCourtyard Room A B11 15 11 45Lecture Glia neuron interactions in nervous system assemblyGeorgia Rapti EMBL Heidelberg GermanyCourtyard Room A B11 45 12 00Meet the speaker Georgia Rapti EMBL Heidelberg GermanyCourtyard Room A B12 00 12 30Feedback session and closing remarksCourtyard Room A B12 30Bus from EMBL to Heidelberg city center train station or Walk to ISGATC Entrance Practical information Registration fees and motivation letter The course is limited to 16 participants For selection purposes please note that your application will not be considered without a letter of motivation Registration Registration fees include admission course materials meals and coffee breaks This EMBO course includes accommodation and transportation to and from the ISG Hotel to the venue Academia 500PhD Student 500Industry 1000 A letter to support your visa application will be issued on request once payment of the registration fee is confirmed We recommend that you book your visa appointment as soon as possible to avoid any delay with your visa application Confirmation and payment The registration fee should be paid only after acceptance to the course The results will be announced approximately 2 3 weeks after the application deadline Motivation letter submission After you have logged in and successfully registered you will receive an email asking you to submit your motivation letter Click on the link provided and enter your motivation letter in the text box provided Alternatively you can submit your motivation letter by clicking on the link on the confirmation page directly after registering Instructions Include your relevant skills experience and qualifications showing why you would be suitable for the course Explain why you would like to attend including what you can contribute and how you think you will benefit from the course Please note The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised For detailed instructions please watch our video on how to submit a course motivation letter Further details For further information about registration and motivation letter submission please refer to the FAQ page Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of registration fee waivers travel grants and childcare grants Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course Travel grant The travel grant will cover the cost of travel airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Course within Europe up to 1000 for participants travelling to an EMBL Course from outside Europe up to 500 for any participant travelling to an EMBO Practical Course up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Practical Course up to 700 for any participant working in Croatia Czech Republic Estonia Greece Hungary Italy Lithuania Luxembourg Poland Slovenia and Turkey travelling to an EMBO Practical Course Registration fees are only covered for EMBO Practical Courses The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant There is the possibility to apply for a childcare grant to offset child care costs incurred by participants speakers trainers and organisers when attending a course Eligible costs include but are not limited to fees for a babysitter or child care facility and travel costs for a caregiver Please note that priority will be given to early stage researchers There is a limited amount of funding available for the childcare grants and funds will be distributed amongst eligible applicants Boehringer Ingelheim Fonds travel grant Applies to selected courses only Availability will be indicated during the motivation letter submission process This grant covers costs related to your attendance at the course registration travel and accommodation costs The grant is restricted to PhD students and postdocs who conduct basic biomedical research Whether you are eligible to apply for a travel grant depends on when you received your university entrance qualification e g Abitur A Levels High School Diploma Final State Examination for PhD and MD students as well as graduates the university entrance qualification must not have been obtained more than 11 years ago at the time of the envisaged course for postdocs the university entrance qualification must not have been obtained more than 13 years ago at the time of the envisaged course Application You may apply for financial assistance when submitting your motivation letter for courses In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application For the Boehringer Ingelheim Fonds Travel Grant there is a pre application question during the motivation letter submission process and if selected you will be requested to complete a standard form and documentation consisting of your travel expense estimation Selection The scientific organisers will select the recipients of registration fee waivers and travel grants during the motivation letter or abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection for registration fee waivers and travel grants is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Childcare grants will be allocated in the same timeframe 6 8 weeks before the event start date Please note that priority will be given to early stage researchers Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details See our list of external funding opportunities and for further information about financial assistance please refer to the FAQ page Accommodation and travel For travel information please see here If you are travelling to the conference within Germany then you are eligible for the Deutsche Bahn Event Ticket called the Veranstaltungsticket in German This will result in a lower ticket price if your travel distance to Heidelberg is more than 100 km You need to provide proof of your event attendance when purchasing the ticket For more information in English see here or in German see here You can book your ticket here Hotel Accommodation in single rooms including breakfast is included in the registration fee Accommodation has been booked for you at the ISG Hotel for the default dates of 8 to 15 7 nights This should be paid by you directly to the ISG during your stay Any additional nights need to be booked and paid for by you We recommend that all course participants stay at the ISG Hotel which is the dedicated hotel for the course Local transport Shuttle buses will go from the ISG Hotel to EMBL and back mornings and evenings A bus schedule and location of the bus stops will be made available prior to the meeting Further details Address EMBL Heidelberg Meyerhofstra e 1 69117 Heidelberg GermanyFor more information about accommodation and travel please refer to the FAQ page On site information Catering All meals and coffee breaks are included in the registration fee Our catering staff will prepare a wide variety of vegetarian meals meat and fish dishes soups pasta fresh fruit and vegetables as well as a variety of desserts Please wear your badge at all times when serving yourself No food or drinks are allowed in the laboratories Electricity and charging station In most places the electricity is 220 volts AC 50 cycles An adaptor and a plug that fits the German socket may be needed for your appliances laptop i e American Japanese etc A USB charging station for electronic devices is available at the registration desk EMBL Merchandise If you are interested in purchasing EMBL merchandise products presented in the glass display in the registration area please email the EMBL shop to place an order or get in contact with your Course Organiser Kindly note the EMBL shop is only open upon request and all purchases must be made in cash Euros only Health and safety notes Please read EMBL s COVID 19 safety policy for on site events Do not smoke in any EMBL building Eating and drinking is prohibited in all laboratories Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required The first aid room is located next to the ATC Registration Desk room 10 205 Dial the Emergency number 222 from any EMBL internal phone only Where is the accident What happened How many injured Emergency number 06221 387 7821 from mobile phones Please report all accidents to the conference officer at the registration desk In case of fire Press the nearest fire alarm button or the Emergency number 222 from any internal phone A loud fire alarm will go off if an evacuation is required On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting points Do not use the lifts Beyond first aid Please remember to bring your own medication if needed to the conference Note that the next pharmacy is a 4 minute drive from the EMBL but for many medications you will be required to see a doctor to get a prescription Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg In any case the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary Internet Wi Fi is available on campus Log in using the EMBL Events network and the event specific password which will be provided on site The eduroam network secure worldwide roaming access service developed for the international research and education community is also available Lost and found Lost and Found items are kept at the registration desk until the end of the conference Luggage There are lockers available on site to store your luggage which require a 2 EURO coin to operate There is another luggage room on level E0 which is free to use but remains unlocked during the conference Nursing room There is a nursing room available in the ATC Rooftop Lounge on level A29 Photography During the conference an EMBL Photographer may be taking photos If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Printing We can help to print your boarding pass train ticket Please send it to events embl de and collect your print outs at the registration desk Room for prayer yoga and meditation There is a room for prayer meditation and yoga located on level E0 behind the Auditorium Please be respectful of others using the room Sightseeing A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing Travel to and from the venue During the event we provide conference shuttle buses to and from EMBL In addition there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time Information on the shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page Map to walk from ISG Hotel to EMBL Additional information Address EMBL Heidelberg Meyerhofstra e 1 69117 Heidelberg Germany ATC orientation map Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page Technical requirements and event software Technical requirements Below you will find the software and technical requirements for this course Participants need to bring their own laptops which will be used to remotely access EMBL virtual machines with pre installed software You will need admin rights to install the software required to access the virtual machines If you do not have admin rights please contact your technical support team in advance to make sure the software can be installed If you have a non standard HDMI port other than type A you need to bring an adaptor Keyboard and PC mouse are available for use with a standard USB port If you have a different port type such as USB C you will need to bring your own Event software The EMBL eCampus learning platform will be used to collaborate communicate and network with all of the course participants All participants will receive information on how to join shortly before the course We recommend using Chrome Safari or Mozilla Firefox browsers for eCampus Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page COVID 19 related questions COVID 19 information for on site events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Event partner Event sponsors Event supporters Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other events or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1600 900 PPT Slide 16 x9...

Henrik Bringmann, Simone Koehler, Georgia Rapti, Pavak Shah

EMBO Practical Course

EMBL Heidelberg

Edit

May 26, 2024 00:002024CourseEMBL Heidelberg

Description OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview Course overview This course will teach the biological researchers how to analyse biological data sets using open source software Most of the analysis will be performed with docker4seq and rCASC packages which was developed to facilitate the use of computing demanding applications in the field of NGS data analysis Docker4seq and rCASC packages use docker containers that embed demanding computing tasks e g short reads mapping into isolated containers This approach provides multiple advantages the user does not need to install all the software on its local server the results generated by different containers can be organised in pipelines and reproducible research is guarantee by the possibility of sharing the docker images used for the analysis Computers for hands on exercises will be provided along with demo data sets Audience This course was developed for biological researchers as the intended audience Basic knowledge of massively parallel sequencing MPS is desirable however R coding skills and deep knowledge of statistics are not necessary What past participants say about the course My research focus is on RNA sequencing infectious diseases and next generation sequencing Attending this course helped me understand the basics got me career advice and extended my network Overall it made me a better researcher Abhay Deep Pandey Translational Health Science And Technology Institute India Excellent course on the complete spectrum of RNA Seq I would highly recommend this course to all biologists Issaac Rajan King Abdullah University of Science and Technology Saudi Arabia Speakers Marco Beccuti University of Turin Italy Vladimir Benes EMBL Heidelberg Germany Raffaele Calogero University of Turin Italy Francesca Cordero University of Turin Italy Scientific organisers Marco Beccuti University of Turin Italy Vladimir Benes EMBL Heidelberg Germany Raffaele Calogero University of Turin Italy Francesca Cordero University of Turin Italy Course organisers Charlotte Courtney Course and Conference Officer EMBL Heidelberg Germany Training Lab Technician EMBL Heidelberg Germany Programme Are you on social media Post using EMBLDataAnalysis and don t forget to tag EMBLEvents Some pre course work such as watching pre recordings protocol reading and computational exercises with estimated time 0 10 hours may be required and if so will be shared in advance of the course Some speakers may need to join virtually to give their lecture or Q A and the programme is subject to change Day 1 Sunday 26 May 2024 Time Berlin Europe SpeakerLocation14 00 14 30Welcome and course overviewVladimir Benes EMBL Heidelberg GermanyCharlotte Courtney EMBL Heidelberg GermanyISG Hotel meeting room Weimar Dessau14 30 15 00Participants flash talksISG Hotel meeting room Weimar Dessau15 00 16 00RNA seq cool but is it that simple Vladimir Benes EMBL Heidelberg GermanyISG Hotel meeting room Weimar Dessau16 00 16 30Coffee BreakISG Hotel meeting room Weimar Dessau16 30 18 00RNA seq cool but is it that simple Vladimir Benes EMBL Heidelberg GermanyISG Hotel meeting room Weimar Dessau18 00 19 00DinnerISG Hotel beer garden Day 2 Monday 27 May 2024 Time Berlin Europe SpeakerLocation08 40Bus from ISG to EMBLISG Hotel entrance09 00 10 00Docker container and reproducibilityMarco Beccuti University of Turin ItalyComputer Training Lab10 00 10 30Coffee BreakATC Foyer10 30 11 00Experimental design bulk RNAseqRaffaele Calogero University of Turin ItalyComputer Training Lab11 00 12 00QC bulk RNAseqRaffaele Calogero University of Turin ItalyComputer Training Lab12 00 13 00LunchEMBL Canteen13 00 14 30Counting reads bulk RNAseqRaffaele Calogero Marco Beccuti University of Turin ItalyComputer Training Lab14 30 15 00Coffee BreakATC Foyer15 00 17 30Counting reads miRNAFrancesca Cordero University of Turin ItalyComputer Training Lab17 30 18 30Social programme Facility tour18 30 19 30DinnerEMBL Canteen19 45Bus to ISG HotelATC Entrance Day 3 Tuesday 28 May 2024 Time Berlin Europe SpeakerLocation08 40Bus from ISG to EMBLISG Hotel entrance09 00 10 30PCA a linear dimensionality reduction methodRaffaele Calogero University of Turin ItalyComputer Training Lab10 30 11 00Coffee BreakATC Foyer11 00 12 30Differential expression analysis for bulk RNAseqRaffaele Calogero University of Turin ItalyComputer Training Lab12 30 13 30LunchEMBL Canteen13 30 14 30Differential expression analysis for multiple groups ANOVA likeRaffaele Calogero University of TurinComputer Training Lab14 30 16 00Visualising differentially expressed data Heat maps Raffaele Calogero Marco Beccuti University of Turin ItalyComputer Training Lab16 00 16 30Coffee BreakATC Foyer16 30 18 00Mining differential expression results for bulk RNAseqRaffaele Calogero University of Turin ItalyComputer Training Lab18 00 19 00Pizza dinner in the Rooftop LoungeRooftop lounge19 00Bus to ISG HotelATC Entrance Day 4 Wednesday 29 May 2024 Time Berlin Europe SpeakerLocation08 40Bus from ISG to EMBLISG Hotel entrance09 00 10 00Exercises on Mining differential expression results for bulk RNAseqRaffaele Calogero University of Turin ItalyComputer Training Lab10 00 11 00Experimental design scRNAseqCounting reads single cells RNAseqRaffaele Calogero University of Turin ItalyComputer Training Lab11 00 11 30Coffee BreakATC Foyer11 30 12 30QC single cells RNAseqRaffaele Calogero University of Turin ItalyComputer Training Lab12 30 13 30Lunch and group photoEMBL Canteen13 30 15 00Non linear dimensionality reduction for single cell RNAseqRaffaele Calogero University of TurinComputer Training Lab15 00 16 00Sub population discovery in single cell RNAseq clusteringRaffaele Calogero Marco Beccuti University of Turin ItalyComputer Training Lab16 00 16 30Coffee BreakATC Foyer16 30 18 00Annotating cell types after sub population discoveryRaffaele Calogero University of Turin ItalyComputer Training Lab18 00Bus to ISG from EMBL ATC 20 minutes at ISG hotel to drop things ATC Entrance18 30Bus from ISG to Neckarm nzplatzISG Hotel19 00Downtown dinnerOskars Day 5 Thursday 30 May 2024 Time Berlin Europe SpeakerLocation08 40Bus from ISG to EMBLISG Hotel entrance09 00 10 00scRNA data integration Raffaele Calogero University of Turin ItalyMarco Beccuti University of Turin ItalyComputer Training Lab10 00 11 00ExercisesComputer Training Lab11 00 11 30Coffee BreakATC Foyer11 30 12 30Individual exercises on bulk RNAseqRaffaele Calogero University of Turin ItalyMarco Beccuti University of Turin ItalyComputer Training Lab12 30 13 30LunchEMBL Canteen13 30 16 00Individual exercises on bulk RNAseqRaffaele Calogero University of Turin ItalyMarco Beccuti University of Turin ItalyComputer Training Lab16 00 16 30Coffee BreakATC Foyer16 30 17 30Individual exercises on bulk RNAseqRaffaele Calogero University of Turin ItalyMarco Beccuti University of Turin ItalyComputer Training Lab17 30 18 30Individual exercises on bulk RNAseqRaffaele Calogero University of Turin ItalyMarco Beccuti University of Turin ItalyComputer Training Lab18 30 19 30DinnerEMBL Canteen19 30Bus to ISG HotelATC Entrance Day 6 Friday 31 May 2024 Time Berlin Europe SpeakerLocation08 40Bus from ISG to EMBLISG Hotel entrance09 00 11 00Individual exercises on single cell RNAseqRaffaele Calogero University of Turin ItalyMarco Beccuti University of Turin ItalyComputer Training Lab11 00 11 30Coffee BreakATC Foyer11 30 12 30Individual exercises on single cell RNAseqRaffaele Calogero University of Turin ItalyMarco Beccuti University of Turin ItalyComputer Training Lab12 30 13 30LunchEMBL Canteen13 30 16 00Individual exercises on single cell RNAseqRaffaele Calogero University of Turin ItalyMarco Beccuti University of Turin ItalyComputer Training Lab16 00 16 20Final remarksVladimir Benes Raffaele Calogero Marco BeccutiComputer Training Lab16 30Bus to Heidelberg train stationATC Entrance Practical information Registration fees and motivation letter The course is limited to 28 participants For selection purposes please note that your application will not be considered without a letter of motivation Registration Registration fees include admission course materials meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Academia 715PhD Student 715Industry 1225 A letter to support your visa application will be issued on request once payment of the registration fee is confirmed We recommend that you book your visa appointment as soon as possible to avoid any delay with your visa application Confirmation and payment The registration fee should be paid only after acceptance to the course The results will be announced approximately 2 3 weeks after the application deadline Motivation letter submission After you have logged in and successfully registered you will receive an email asking you to submit your motivation letter Click on the link provided and enter your motivation letter in the text box provided Alternatively you can submit your motivation letter by clicking on the link on the confirmation page directly after registering Instructions Include your relevant skills experience and qualifications showing why you would be suitable for the course Explain why you would like to attend including what you can contribute and how you think you will benefit from the course Please note The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised For detailed instructions please watch our video on how to submit a course motivation letter Further details For further information about registration and motivation letter submission please refer to the FAQ page Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of registration fee waivers travel grants and childcare grants Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course Travel grant The travel grant will cover the cost of travel airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Course within Europe up to 1000 for participants travelling to an EMBL Course from outside Europe up to 500 for any participant travelling to an EMBO Practical Course up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Practical Course up to 700 for any participant working in Croatia Czech Republic Estonia Greece Hungary Italy Lithuania Luxembourg Poland Slovenia and Turkey travelling to an EMBO Practical Course Registration fees are only covered for EMBO Practical Courses The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant There is the possibility to apply for a childcare grant to offset child care costs incurred by participants speakers trainers and organisers when attending a course Eligible costs include but are not limited to fees for a babysitter or child care facility and travel costs for a caregiver Please note that priority will be given to early stage researchers There is a limited amount of funding available for the childcare grants and funds will be distributed amongst eligible applicants Boehringer Ingelheim Fonds travel grant Applies to selected courses only Availability will be indicated during the motivation letter submission process This grant covers costs related to your attendance at the course registration travel and accommodation costs The grant is restricted to PhD students and postdocs who conduct basic biomedical research Whether you are eligible to apply for a travel grant depends on when you received your university entrance qualification e g Abitur A Levels High School Diploma Final State Examination for PhD and MD students as well as graduates the university entrance qualification must not have been obtained more than 11 years ago at the time of the envisaged course for postdocs the university entrance qualification must not have been obtained more than 13 years ago at the time of the envisaged course Application You may apply for financial assistance when submitting your motivation letter for courses In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application For the Boehringer Ingelheim Fonds Travel Grant there is a pre application question during the motivation letter submission process and if selected you will be requested to complete a standard form and documentation consisting of your travel expense estimation Selection The scientific organisers will select the recipients of registration fee waivers and travel grants during the motivation letter or abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection for registration fee waivers and travel grants is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Childcare grants will be allocated in the same timeframe 6 8 weeks before the event start date Please note that priority will be given to early stage researchers Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details See our list of external funding opportunities and for further information about financial assistance please refer to the FAQ page Accommodation and travel Travel information For travel information please see here If you are travelling to the conference within Germany then you are eligible for the Deutsche Bahn Event Ticket called the Veranstaltungsticket in German This will result in a lower ticket price if your travel distance to Heidelberg is more than 100 km You need to provide proof of your event attendance when purchasing the ticket For more information in English see here or in German see here You can book your ticket here Hotel Accommodation is not included in the registration fee Participants are expected to book and pay for their own accommodation A mix of single and twin rooms have been reserved for 6 nights from Saturday 25 May Friday 31 May 2024 at the ISG Hotel Single rooms are limited and will be available on a first come first served basis After the selection process selected participants should contact the hotel directly to make a booking with a booking code code of your course e g DAT24 01 by the deadline of Monday 29 April 2024 We recommend that all course participants stay in the dedicated hotel for the course Local transport Shuttle buses will go from the ISG Hotel to EMBL and back mornings and evenings A bus schedule and location of the bus stops will be made available prior to the meeting Further details Address EMBL Heidelberg Meyerhofstra e 1 69117 Heidelberg GermanyFor more information about accommodation and travel please refer to the FAQ page On site information Catering All meals and coffee breaks are included in the registration fee Our catering staff will prepare a wide variety of vegetarian meals meat and fish dishes soups pasta fresh fruit and vegetables as well as a variety of desserts Please wear your badge at all times when serving yourself No food or drinks are allowed in the laboratories Electricity and charging station In most places the electricity is 220 volts AC 50 cycles An adaptor and a plug that fits the German socket may be needed for your appliances laptop i e American Japanese etc A USB charging station for electronic devices is available at the registration desk EMBL Merchandise If you are interested in purchasing EMBL merchandise products presented in the glass display in the registration area please email the EMBL shop to place an order or get in contact with your Course Organiser Kindly note the EMBL shop is only open upon request and all purchases must be made in cash Euros only Health and safety notes Please read EMBL s COVID 19 safety policy for on site events Do not smoke in any EMBL building Eating and drinking is prohibited in all laboratories Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required The first aid room is located next to the ATC Registration Desk room 10 205 Dial the Emergency number 222 from any EMBL internal phone only Where is the accident What happened How many injured Emergency number 06221 387 7821 from mobile phones Please report all accidents to the conference officer at the registration desk In case of fire Press the nearest fire alarm button or the Emergency number 222 from any internal phone A loud fire alarm will go off if an evacuation is required On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting points Do not use the lifts Beyond first aid Please remember to bring your own medication if needed to the conference Note that the next pharmacy is a 4 minute drive from the EMBL but for many medications you will be required to see a doctor to get a prescription Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg In any case the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary Internet Wi Fi is available on campus Log in using the EMBL Events network and the event specific password which will be provided on site The eduroam network secure worldwide roaming access service developed for the international research and education community is also available Lost and found Lost and Found items are kept at the registration desk until the end of the conference Luggage There are lockers available on site to store your luggage which require a 2 EURO coin to operate There is another luggage room on level E0 which is free to use but remains unlocked during the conference Nursing room There is a nursing room available in the ATC Rooftop Lounge on level A29 Photography During the conference an EMBL Photographer may be taking photos If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Printing We can help to print your boarding pass train ticket Please send it to events embl de and collect your print outs at the registration desk Room for prayer yoga and meditation There is a room for prayer meditation and yoga located on level E0 behind the Auditorium Please be respectful of others using the room Sightseeing A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing Travel to and from the venue During the event we provide conference shuttle buses to and from EMBL In addition there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time Information on the shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page Map to walk from ISG Hotel to EMBL Additional information Address EMBL Heidelberg Meyerhofstra e 1 69117 Heidelberg Germany ATC orientation map Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page Technical requirements and event software delete the technical requirements part if it is not a computer based course in the courtyard room as well as change label of the details section to only Event Software Technical requirements Below you will find the software and technical requirements for this course Participants need to bring their own laptops which will be used to remotely access EMBL virtual machines with pre installed software You will need admin rights to install the software required to access the virtual machines If you do not have admin rights please contact your technical support team in advance to make sure the software can be installed If you have a non standard HDMI port other than type A you need to bring an adaptor Keyboard and PC mouse are available for use with a standard USB port If you have a different port type such as USB C you will need to bring your own Event software The EMBL eCampus learning platform will be used to collaborate communicate and network with all of the course participants All participants will receive information on how to join shortly before the course We recommend using Chrome Safari or Mozilla Firefox browsers for eCampus Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page COVID 19 related questions COVID 19 information for on site events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other events or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9...

Marco Beccuti, Vladimir Benes, Raffaele Calogero, Francesca Cordero

EMBL Heidelberg

24 May 2024

Interpreting the effects of genetic variants on protein structure and function

Edit

May 24, 2024 00:002024CourseVirtual

Description Genetic variation between individuals results in a range of human phenotypes Variants that fall within coding regions of genes generally have direct effects on the proteins encoded by the genes with which they overlap This six hour virtual workshop will provide participants with an opportunity to gain hands on experience of using EMBL EBI tools and resources to assess the effects of genetic variants on the structure and function of proteins in a common workflow During the course a single example will be used throughout using different EMBL EBI tools and resources at each stage of the analysis pipeline The example will involve running a VCF file through the Ensembl Variant Effect Predictor VEP then following links to UniProt PDBe and AlphaFoldDB for further variant information and interpretation Virtual courseThis course will take place on Zoom Trainers will be available to assist during practical sessions answer questions and provide further explanations during the Zoom To join the course you will need to create an EMBL EBI Training website account...

Meredith Willmott

Virtual

21 May - 23 May 2024

BioMalPar XX: biology and pathology of the malaria parasite

Edit

May 21, 2024 00:002024ConferenceEMBL Heidelberg, Virtual

Description OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Conference overview Malaria remains a major global public health challenge The emergence and spread of resistance to existing antimalarial drugs further complicates the fight against this ancient foe As the BioMalPar Conference marks its 20th anniversary we would like to take a moment to reflect on the critical mission of understanding the biology of the Plasmodium parasite its interactions with hosts and vectors and the urgent need to develop effective intervention strategies This year we will focus on enhancing our research community by forging new connections We recognize that meaningful progress in combating malaria necessitates collaboration across continents and disciplines sharing data and employing state of the art techniques to unravel Plasmodium s secrets The upcoming conference is a pivotal opportunity for global scientists to convene fostering the exchange of vital information cutting edge technology and innovative ideas all crucial to advancing our collective battle against malaria Session topics Imaging Begins Revenge of the Mosquito Charlie the Vaccine Factory Mr Mrs Plasmodium V for Vivax The Parasite s Guide to the Galaxy What past participants say about the conference BioMalPar 2023 encompassed a spectacular range of research spanning basic to translational The program content was topical and comprehensive and the overall event was well organized to achieve a dynamic environment that fuelled great discussions and networking Jacquin Niles Massachusetts Institute of Technology USA After a decade working on malaria research I had heard high opinions of BioMalPar However this was my first time attending and clearly exceeded my expectations Excellent scientific content with a balanced blend of senior and junior scientists Smoothly organised in a venue that favours networking organically Alejandro Marin Menendez MIVEGEC IRD France Speakers Keynote Speaker Ally Olotu Ifakara Health Institute Tanzania Virtual speaker Speakers Takeshi Annoura National Institute of Infectious Diseases NIID Japan Nsa Dada Arizona State University USA Alfred Cort s ISGlobal Spain Emily Derbyshire Duke University USA Tibebu Habtewold Imperial College London UK Franziska Hentzschel Heidelberg University Hospital Germany Chi Min Ho Columbia University Irving Medical Center USA Felix Hol Radboud University Medical Center The Netherlands Mallika Imwong Mahidol University Thailand Virtual speaker Berlin Londo o Renteria Tulane University USA Fitsum G Tadesse Armauer Hansen Research Institute Ethiopia Moritz Treeck Gulbenkian Institute of Science Portugal Scientific Organisers Sabrina Absalon Indiana University School of Medicine USA Jessica Bryant Institut Pasteur France Fredros Okumu Ifakara Health Institute Tanzania Taco Kooij Radboud University Medical Center The Netherlands Emeritus steering group member Julian Rayner University of Cambridge UK Andy Waters University of Glasgow UK Conference Organiser Chris Stocks EMBL Heidelberg Germany Programme Are you on social media Post using EMBLMalaria and don t forget to tag EMBLEvents Please note that the programme is subject to change Some speakers may need to join virtually to give their talk For registered participants recorded talks will be accessible on demand for 2 weeks after the end of the event unless indicated otherwise Day 1 Tuesday 21 May 2024 Time Europe Berlin Speaker09 00 10 30Registration10 30 10 45Opening remarks10 45 11 45Keynote speaker A comprehensive approach to malaria elimination vaccines infrastructure and innovationAlly Olotu Ifakara Health Institute Tanzania Virtual speaker 11 45 15 15Session 1 Imaging Begins Chairs Nedal Djamil Darif EMBL Heidelberg GermanyMarkus Ganter Heidelberg University Germany 11 45 12 00A novel Dynamin interactor is required for malaria parasite apicoplast inheritanceJames Blauwkamp Indiana University School of Medicine USA12 00 12 15Imaging Plasmodium berghei gametocyte behaviour in the skinMatthew Gibbins University of Glasgow UK12 15 13 45Lunch and meet the speakers13 45 14 15Inhibiting elongation factor binding to the malarial 80S ribosome triggers ribosome biogenesisChi Min Ho Columbia University Irving Medical Center USA14 15 14 30Cryo EM structural analysis of broadly inhibitor antibodies against severe malaria associated PfEMP1Sai Sundar Rajan Raghavan The Scripps Research Institute USA14 30 14 45Multiple CENP C homologues are essential for mitosis and connect the inner kinetochore with chromosomes in malaria parasitesJessica Kimmel Bernhard Nocht Institute for Tropical Medicine Germany14 45 15 15Plasmodium cynomolgi an excellent model for imaging and valuable clue to understanding relapse and asymptomatic mechanisms in malaria endemic areasTakeshi Annoura National Institute of Infectious Diseases NIID Japan15 15 16 00Coffee break and meet the speakers16 00 17 30Session 2 V for Vivax Chairs Nicole Kilian California State University USAJerzy Dziekan Walter and Eliza Hall Institute of Medical Research Australia16 00 16 30What drives P vivax transmission Fitsum G Tadesse Armauer Hansen Research Institute Ethiopia16 30 16 45P vivax induced bone marrow alterations persist long after acute phase of infectionJoao Luiz Silva Filho University of Glasgow UK16 45 17 00Innocent residents or drivers of change investigating cell composition and interaction changes by Plasmodium infection in the bone marrow and spleenJoy Kabagenyi University of Glasgow UK17 00 17 30Anopheles gambiae population replacement using gene drive for malaria elimination in AfricaTibebu Habtewold Imperial College London UK17 30 17 55Flash talks 63 Luis Izquierdo 65 Ana Maria Filipe 75 Maria Ivanova 85 Patricia Landeau Millan 95 Hangjun Ke 97 Korbinian Niederm ller 99 Sarah Pashley 101 Christiaan van Ooij17 55 19 30Poster session 1 odd numbers 19 30 21 00Dinner21 00 22 30After dinner drinks in ATC Rooftop lounge Day 2 Wednesday 22 May 2024 Time Europe Berlin Speaker09 00 12 15Session 3 The Parasite s Guide to the Galaxy Chairs Caroline Ng University of Nebraska Medical Center USANicolas Brancucci Swiss TPH Switzerland09 00 09 30Interdisciplinary approaches to reveal Plasmodium parasite vulnerabilitiesEmily Derbyshire Duke University USA09 30 09 45Jumonji C demethylase 1 and 2 guardians of the euchromatin in Plasmodium falciparumJonas Gockel Radboud University The Netherlands09 45 10 00A metabolic switch controls ribosome heterogeneity in the human malaria parasiteJustine Couble Institut Pasteur France10 00 10 15A homing gRNA pilot screen in P berghei oocysts identifies a chloroquine resistance transporter like protein of the food vacuole essential for mosquito transmissionArjun Balakrishnan Ume University Sweden10 15 11 00Coffee break and meet the speakers11 00 11 30Expand Export Diversify and Conquer The FIKK kinase family in P falciparum host pathogen interactionMoritz Treeck The Francis Crick Institute UK and Gulbenkian Institute of Science PortugalNot available on demand11 30 11 45Stopping malaria parasites before they START aryl amino acetamides prevent ring development via inhibition of the lipid transfer protein PfSTART1Coralie Boulet Universit de Gen ve Switzerland11 45 12 00Plasmepsin V is essential for Plasmodium liver stage development via suppression of innate immunityEva Hesping Walter and Eliza Research Institute Australia12 00 12 15Order in chaos structural electron microscopy reveals the formation of a malarial maternal maintenance mechanism during ookinete developmentThanat Chookajorn Umea University Sweden Virtual short talk 12 15 13 45Lunch and meet the speakers13 45 17 00Session 4 Revenge of the Mosquito Chairs Wasim Hussein Heidelberg University Hospital GermanyLaura de Vries Harvard T H Chan Public School of Health USA13 45 14 15The mosquito microbiome the oft neglected component of malaria parasite vector interactionsNsa Dada Arizona State University USA14 15 14 30Malaria vector nutrition predicts rate of Plasmodium falciparum development and infectivityPhilipp Schwabl Harvard University USA14 30 14 45Characterization of Anopheles gambiae mosquitoes swarms using 3D video trackingRoberta Spaccapelo University of Perugia Italy14 45 15 00Flash talks 38 Jeffrey Agyapong 44 Ines Bento 98 Clara Eva Paquerau 110 Parul Singh15 00 15 45Coffee break and meet the speakers15 45 16 15Bloodthirsty Deep behavioral phenotyping reveals how mosquito pathogen interactions shape transmissionFelix Hol Radboud University Medical Center The Netherlands16 15 16 30Non CSP antibodies from immunized volunteers identify mosquito saliva proteins as a new target against P falciparum sporozoitesCarolina Andrade Radboud University Medical Center The Netherlands16 30 16 45Screen of diverse antimalarials reveals druggable Plasmodium falciparum targets for mosquito based malaria interventionAlexandra Probst Harvard T H Chan School of Public Health USA16 45 17 45Lifetime achievement award17 45 19 30Poster session 2 even numbers 19 30 21 00Dinner21 00 00 00After dinner drinks with Live music Day 3 Thursday 23 May 2024 Time Europe Berlin Speaker09 00 11 45Session 5 Mr Mrs Plasmodium Chairs David Guttery University of Leicester UKNisha Philip University of Edinburgh UK09 00 09 30Discovery of a divergent Arp2 3 complex essential for male gamete formation and transmissionFranziska Hentzschel Heidelberg University Hospital Germany09 30 09 45Microtubule inner proteins are essential for transmission of PlasmodiumAnnika Binder Heidelberg University Medical School Germany09 45 10 00Haemoglobin beta variants induce elevated Plasmodium falciparum sexual conversion rates in naturally infected individuals in Burkina FasoYasmina Drissi El Boukili Institute of Tropical Medicine Antwerp and University of Antwerp Belgium10 00 10 45Coffee break and meet the speakers10 45 11 15The regulation of the regulator of the regulator of the regulator of sexual conversion in Plasmodium falciparumAlfred Cort s ISGlobal Spain11 15 11 30Cryo EM of native Pfs230 and Pfs48 45 fertilisation complexMelanie H Dietrich Walter and Eliza Hall Institute of Medical Research University of Melbourne Australia11 30 11 45Mitochondrial ATP synthesis is essential for efficient gametogenesis in Plasmodium falciparumMichael Delves London School of Hygiene Tropical Medicine UK Virtual short talk 11 45 13 15Lunch and meet the speakers13 15 15 45Session 6 Charlie the Vaccine Factory Chairs Justin Boddey Walter and Eliza Hall Institute of Medical Research AustraliaNahla Galal Metwally Bernhard Nocht Institute for Tropical Medicine Germany13 15 13 45Evolution of multi drug resistant malaria implications on deployment of triple artemisinin based combination therapiesMallika Imwong Mahidol University Thailand Virtual speaker Not available on demand13 45 14 00Structure guided design of PfRH5 based vaccine immunogens for blood stage malariaNawsad Alam University of Oxford UK14 00 14 15The creation of pan African genetically attenuated Plasmodium falciparum sporozoite vaccines using experimental genetic crossesLucia Pazzagli Seattle Children s USA14 15 14 45Coffee break and meet the speakers14 45 15 00Safety and protection by a late liver stage attenuated malaria parasiteOlivia Lamers Leiden University Medical Center The NetherlandsNot available on demand15 00 15 15Fc afucosylation of VAR2CSA specific IgG and clinical protection against placental malariaMary Lopez Perez University of Copenhagen Denmark15 15 15 45Immune responses against mosquito saliva in chronic and infectious diseaseBerlin Londo o Renteria Tulane University USA15 45 16 00Closing remarks and poster prize announcements Practical information Choosing onsite vs virtual participation You can choose to attend the conference either onsite in Heidelberg or virtually If you hope to present your research you need to decide which mode suits you best before the abstract submission deadline considering the below If you plan to attend the conference onsite you can register and apply for an oral or poster presentation A selection process will take place with the results announced 2 3 weeks after the abstract submission deadline Please note that once you have registered for onsite attendance and submitted an abstract for an oral presentation you will still have the opportunity to present a poster onsite even if not selected for an onsite oral presentation However it is not possible to switch and apply for a virtual oral presentation after the submission deadline If you plan to attend the conference virtually you can only apply for a virtual oral presentation as there will be no virtual posters If your abstract is not selected for a virtual oral presentation you can still participate in the conference with access to all the live streamed talks a video library of the recorded talks and a facility to submit questions Only participants attending the event onsite can present a poster Registration fees and abstract submission On site registration fees include admission conference materials meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Virtual registration fees include access to all of the talks livestreamed and on demand and facility to submit questions On site Academia 735On site PhD Student 635On site Industry 935On site Journal Editors 250Virtual Academia 225Virtual PhD Student 175Virtual Industry 275 Editors from scientific journals are allowed to attend at a reduced rate but asked to contribute to the conference in return by taking part in meet the editors sessions or other planned activities within the programme A letter to support your visa application will be issued on request once payment of the registration fee is confirmed We recommend that you book your visa appointment as soon as possible to avoid any delay with your visa application Accredited journalists may be eligible to register for complimentary press registration Registrants may be required to provide accreditation or equivalent proof of press membership after registration Please contact events embl de for more information Please note that we do not offer complimentary registrations for editors of scientific journals Confirmation and payment Registration will be on a first come first served basis Your place can only be confirmed after payment of the registration fee If you are added to our waiting list please consider taking advantage of our offerings to participate virtually On site participants Types of payments accepted are international bank transfers and credit card payments Virtual participants We are only able to accept card payments In exceptional cases we can accept bank transfers Please contact events embl de for details Abstract submission Onsite and virtual participants registering to attend are eligible to submit an abstract After registration you can submit your abstract via a separate link that will be provided in the email confirmation Alternatively you can access the link on the confirmation page directly after registering The same login credentials are used for both processes Please note Abstract body The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised Title The title should not exceed 20 words Only the first word of the title should start with a capital letter and the rest should be lowercase Authors and affiliations Please fill in the author s details as requested in the online form The compulsory fields are First Name Last Name Organisation Name Affiliation or Company Country and Email Kindly mark only one author in the role of First Author and please don t forget to indicate who will be the Presenter Please enter your co authors correctly via the system by adding accounts together with their organisation institute Do not copy paste them into the body of the abstract text as they will not be indexed in the abstract book Presentation types When submitting your abstract you can apply for an oral or poster presentation A selection process will take place with the results announced 2 3 weeks after the abstract submission deadline For detailed instructions on how to submit a conference abstract follow the instructions provided in this video Please check our FAQs pages for further information on how to submit an abstract Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of registration fee waivers travel grants and childcare grants Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course or conference Travel grant The travel grant will cover the cost of travel to an on site event airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from within Europe up to 1000 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from outside Europe up to 500 for any participant travelling to an EMBO Workshop up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Workshop up to 700 for any participant working in Croatia Czech Republic Estonia Greece Hungary Italy Lithuania Luxembourg Poland Slovenia and Turkey travelling to an EMBO Workshop Registration fees are only covered for EMBO Workshops The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant There is the possibility to apply for a childcare grant to offset child care costs incurred by participants speakers and organisers when attending a conference Eligible costs include but are not limited to fees for a baby sitter or child care facility and travel costs for a caregiver Please note that priority will be given to early stage researchers In order to apply for this grant you must be registered by the abstract submission deadline There is a limited amount of funding available for the childcare grants and funds will be distributed amongst eligible applicants Application On site participants You may apply for financial assistance when submitting your abstract The financial assistance for onsite participation 13 February 2024 Please note that the deadline for applying for financial assistance for BioMalPar is earlier than the abstract submission deadline This is to allow successful applicants more time to apply for a travel visa to enter Germany if needed In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Your abstract will still be considered if you are not awarded financial help and you may still attend on a self funding basis if you wish Virtual participants If you are attending virtually you can apply for financial assistance in the submission portal by the abstract deadline Read the instructions on how to apply for financial assistance In your application you will be asked to summarise your current work answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Selection The scientific organisers will select the recipients of registration fee waivers and travel grants during the motivation letter or abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection for registration fee waivers and travel grants is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Childcare grants will be allocated in the same timeframe 6 8 weeks before the event start date Please note that priority will be given to early stage researchers Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details View our list of external funding opportunities and information on attending a conference as an event reporter For further information about financial assistance please refer to the FAQ page Accommodation and travel Accommodation is not included in the conference registration fee The hotels below have rooms on hold for participants until 23 April 2024 in some cases at special rates Please email the hotel directly quoting the booking code BMP23 01 to confirm the exact price of the room Hotel AnlageHotel ibis HeidelbergPremier Inn Heidelberg CityHotel Bayrischer Hof ISG Hotel Staycity Aparthotel HeidelbergB B HotelLeonardo Hotel Heidelberg City CentreSteffi s Hostel HeidelbergExzellenz HotelMeininger HeidelbergHotel Vier Jahreszeiten HeidelbergHotel Holl nder Hof Hotel MonptiHilton Heidelberg Travel information For travel information please see here If you are travelling to the conference within Germany then you are eligible for the Deutsche Bahn Event Ticket called the Veranstaltungsticket in German This will result in a lower ticket price if your travel distance to Heidelberg is more than 100 km You need to provide proof of your event attendance when purchasing the ticket For more information in English see here or in German see here You can book your ticket here Conference shuttle buses Conference shuttle buses are free of charge for participants and depart from designated bus stops near the hotels to EMBL and back mornings and evenings The bus stops for this conference are Staycity Aparthotel Speyerer Str 7 Kurf rsten Anlage Opposite Main Train Station Premier Inn Kurf rsten Anlage 23 Leonardo Hotel Heidelberg City Center Bergheimer Str 63 Neckarm nzplatz Heidelberg Tourist Information Peterskirche Bus stop ISG Hotel Im Eichwald 19 Conference shuttle bus schedule View Conference shuttle bus stops and hotels in a larger map Please note that not every bus stop will be used for every event You can find the bus schedule here Further details Address EMBL Meyerhofstra e 1 69117 Heidelberg Germany For more information about accommodation and travel please refer to the FAQ page On site information Catering All meals and coffee breaks are included in the registration fee Our catering staff will prepare a wide variety of vegetarian meals meat and fish dishes soups pasta fresh fruit and vegetables as well as a variety of desserts Please wear your badge at all times when serving yourself No food or drinks are allowed in the auditorium Charging lockers There are lockers available next to the stairs leading down into the Auditorium You will find some of those equipped with sockets to charge your smartphone tablet etc Electricity and charging station In most places the electricity is 220 volts AC 50 cycles An adaptor and a plug that fits the German socket may be needed for your appliances laptop i e American Japanese etc A USB charging station for electronic devices is available at the registration desk EMBL merchandise If you are interested in purchasing EMBL merchandise products presented in the glass display in the registration area please email the EMBL shop to place an order or get in contact with your Course Organiser Kindly note the EMBL shop is only open upon request and all purchases must be made in cash Euros only Health and safety notes Please read EMBL s COVID 19 safety policy for on site events Do not smoke in any EMBL building Eating and drinking is prohibited in the Auditorium and all laboratories Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required The first aid room is located next to the ATC Registration Desk room 10 205 Dial the Emergency number 222 from any EMBL internal phone only Where is the accident What happened How many injured Emergency number 06221 387 7821 from mobile phones Please report all accidents to the conference officer at the registration desk In case of fire Press the nearest fire alarm button or the Emergency number 222 from any internal phone A loud fire alarm will go off if an evacuation is required On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting points Do not use the lifts Beyond first aid Please remember to bring your own medication if needed to the conference Note that the next pharmacy is a 4 minute drive from the EMBL but for many medications you will be required to see a doctor to get a prescription Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg In any case the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary Internet Wi Fi is available on campus using the EMBL Events network and the event specific password which will be provided on site The eduroam network secure worldwide roaming access service developed for the international research and education community is also available Lost and found Lost and Found items are kept at the registration desk until the end of the conference Luggage There are lockers available on site to store your luggage which require a 2 EURO coin to operate There is another luggage room on level E0 which is free to use but remains unlocked during the conference Nursing room There is a nursing room available in the ATC Rooftop Lounge on level A29 Photography During the conference an EMBL Photographer may be taking photos If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Printing We can help to print your boarding pass train ticket Please send it to events embl de and collect your print outs at the registration desk Room for prayer yoga and meditation There is a room for prayer meditation and yoga located on level E0 behind the Auditorium Please be respectful of others using the room Sightseeing A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing Travel to and from the venue During the event we provide conference shuttle buses to and from EMBL In addition there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time Information on the conference shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page Useful German expressions HelloHalloGoodbyeAuf Wiedersehen formal Tsch ss informal Good morningGuten MorgenGood afternoonGuten TagGood eveningGuten AbendGood nightGute NachtI m sorryEs tut mir leidExcuse me Entschuldigen SieHow are you Wie gehts I m fine thanks And you Mir geht es gut danke Und Dir Ihnen What is your nameWie hei en Sie formal Wie hei t Du informal My name isIch hei e Do you speak EnglishSprechen Sie englisch I don t understandIch verstehe nichtPlease speak more slowlyK nnen Sie bitte langsamer sprechenThank youDankesch nWhere is the toilet Wo ist die Toilette Please call me a taxiBitte rufen Sie mir ein TaxiHow do I get to Wie komme ich zum zur A beer two beers pleaseEin Bier zwei Bier bitteA glass of red white wine pleaseEin Glas Rot Weisswein bitteThe menu pleaseDie Speisekarte bitteIs there a local speciality Gibt es eine Spezialit t aus dieser Gegend I m vegetarianIch bin VegetarierIt was deliciousEs war hervorragendThe bill pleaseDie Rechnung bitteI have a headacheIch habe KopfschmerzenI have a sore throatIch habe HalsschmerzenMy stomach hurtsIch habe MagenschmerzenI m allergic toIch bin allergisch gegenI need a doctor who speaks EnglishIch brauche einen Arzt der englisch spricht Virtual participation What s included Access to all the livestreamed talks Video library of the recorded talks during the event and for two weeks afterwards Please note at the request of individual speakers some talks are not recorded Facility to submit questions Talks will only be recorded upon speaker s consent Please note that only on site participants are able to submit abstracts and participate in the poster sessions Event platform We are using an event platform for this conference More information about the platform will be shared ahead of the conference Guidelines Do not broadcast the conference to unregistered participants You are encouraged to tweet and post about the event Tweet unless the speaker specifically says otherwise but be mindful of unpublished data Please do not capture transmit or redistribute data presented at the meeting Additional information can be found in our Code of Conduct Health and well being It is important to stay healthy and move around especially when you are attending an event virtually We have put together a few coffee break stretches and yoga videos in the conference platform for you to enjoy during the event How to ask questions Please use the Q A function in the event platform If you have any other questions you can go to the Help Desk in the event platform Click on more on the top menu and click Help Desk Time zone The programme is planned based on the Europe Berlin time zone unless otherwise stated Please take your time zone into consideration when planning your Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for participants page COVID 19 related questions COVID 19 information for on site events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Media partners EMBO Molecular Medicine an EMBO Press journal International Union of Biochemistry and Molecular Biology Medinformatics a Bon View Publishing journal Open Biology a Royal Society journal Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information on sponsoring possibilities If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9 Leaderboard 728 90...

Sabrina Absalon, Jess Bryant, Fredros Okumu, Taco Kooij

EMBL Conference

EMBL Heidelberg, Virtual

15 May 2024

Accessing sequence analysis tools via the new Job Dispatcher website

Edit

May 15, 2024 15:302024WebinarVirtual

Description The Job Dispatcher team at EMBL EBI provides access to various bioinformatics sequence analysis tools EMBOSS Clustal omega NCBI BLAST etc and biological datasets This webinar will introduce the new Job Dispatcher website showcasing how to navigate through various categories of tools and access them for sequence analysis We will also demonstrate the latest features and user documentation of the Job Dispatcher...

Virtual

14 May - 16 May 2024

Open Virtual Ensembl REST API Workshop

Edit

May 14, 2024 00:002024CourseVirtual

Description Work with Ensembl to master the Ensembl REST API and flexibly access genome wide data such as genes variants regulatory features homologues and alignments...

Louisse Paola Mirabueno

Virtual

14 May - 17 May 2024

Cellular mechanisms driven by phase separation

Edit

May 14, 2024 00:002024ConferenceEMBL Heidelberg, Virtual

Description OverviewSpeakersProgrammePractical informationSponsorsInstrument contestAboutMedia kit Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Symposium overview Phase separation is emerging as a common biophysical principle underlying many important cellular functions This conference will bring together scientists from cell biology biophysics biochemistry molecular biology structural biology developmental biology polymer physics and soft matter physics to study condensates in biology and disease The goals of this symposium are to increase our understanding of the physiological relevance of condensates in many biological processes explore the large repertoire of new tools and methods that can be applied to study the phenomenon of biological condensates provide transdisciplinary training to tackle the role of condensates in biology Session topics Membraneless compartments in the cell Molecular mechanisms of condensate assembly Phase separation a polymer physics perspective Condensates in cellular quality control Protein structure in the condensed state Condensates in gene expression Emerging technologies What past participants say about the Symposium I have never been to a conference where every single talk was relevant exciting and well done This is particularly phenomenal given the interdisciplinary nature of this field Carlos Castaneda Syracuse University USA Although Intrinsically Disordered Proteins and Phase Separation have been around for a number of years this meeting felt like the kick off for a novel area in molecular biology Roland Dosch University Medical Center G ttingen Germany This was the best conference I have attended in years bringing together biophysicists and biologists in an exciting and challenging format I learnt a lot and have made great contacts for new collaborations Sarah Mizielinska Kings College London UK Speakers Keynote Speakers Tanja Mittag St Jude Children s Research Hospital USA Rohit Pappu Washington University in St Louis USA Speakers Serena Carra University of Modena and Reggio Emilia Italy Amy Gladfelter Duke University USA Maria Hondele University of Basel Switzerland Anthony Hyman Max Planck Institute of Molecular Cell Biology and Genetics Germany Ankur Jain Whitehead Institute for Biomedical Research USA Tuomas Knowles University of Cambridge UK Hyun Kate Lee University of Toronto Canada Edward Lemke Institute of Molecular Biology and Johannes Gutenberg University Mainz Germany Tim Nott King s College London UK Michael Rosen The University of Texas Southwestern Medical Center USA Ritwick Sawarkar University of Cambridge UK Ben Schuler University of Zurich Switzerland Yongdae Shin Seoul National University Korea Agnes Toth Petroczy Max Planck Institute of Molecular Cell Biology and Genetics Germany Steph Weber McGill University Canada Scientific Organisers Simon Alberti Dresden University of Technology Germany Sara Cuylen H ring EMBL Heidelberg Germany Dorothee Dormann Institute of Molecular Biology and Johannes Gutenberg University Mainz Germany Alex Holehouse Washington University in St Louis USA Conference organiser Sophie Dutzi EMBL Heidelberg Germany Programme Are you on social media Post using EESPhaseSeparation and don t forget to tag EMBLEvents Please note that the programme is subject to change Some speakers may need to join virtually to give their talk For registered participants recorded talks will be accessible on demand for 2 weeks after the end of the event unless indicated otherwise Day 1 Tuesday 14 May 2024 Time Europe Berlin Speaker12 00 14 00Registration and light refreshments14 00 14 15Opening remarks 14 15 15 15Keynote lecture Interphases Interfaces and MicrophasesRohit Pappu Washington University in St Louis USA15 15 17 30Session 1 Membraneless compartments in the cellChair Sara Cuylen H ring EMBL Heidelberg Germany15 15 15 45Intracondensate demixing and the onset of diseaseTony Hyman Max Planck Institute of Molecular Cell Biology and Genetics Germany15 45 16 00Targeted perturbation of signaling driven condensatesJurian Schuijers UMC Utrecht The Netherlands16 00 16 15Nucleolus ejects internal components by altering its material properties upon arresting RNA fluxYuki Hayashi EMBL Heidelberg GermanyNot available on demand16 15 16 30Specificity of condensate composition regulates transcriptionBenjamin Sabari UT Southwestern Medical Center USA16 30 17 00Coffee break and meet the speakers17 00 17 30Identifying condensate forming proteins regardless of their structural disorder across organismsAgnes Toth Petroczy Max Planck Institute of Molecular Cell Biology and Genetics Germany17 30 18 00Flash Talk Session 1 125 Geng Jen Jang 127 Ramona J hlen 173 Stefan Niekam 175 Henri Niskanen 187 Aline Reuter 191 Tom Scheidt 201 Alexandra Shelest 203 Min Kyung Shinn 239 Theodore Yang 245 Jason Zhang18 00 19 30Poster Session 1 odd numbers 19 30 21 00Dinner in Canteen21 00 22 00After dinner drinks in ATC Foyer Day 2 Wednesday 15 May 2024 Time Europe Berlin Speaker09 00 11 15Session 2 Molecular mechanisms of condensate assemblyChair Alex Holehouse Washington University School of Medicine USA09 00 09 30Modulating DEAD box protein phase transitions with charge and ionsTim Nott King s College London UK09 30 09 45Surface condensation drives tight junction belt assembly in epithelial tissue sealingDaxiao Sun Technische Universit t Dresden MPI CBG Germany09 45 10 00Quantifying collective interactions in biomolecular phase separationHannes Ausserw ger University of Cambridge UK10 00 10 30Coffee break and meet the speakers10 30 10 45O GlcNAcylation and poly ADP ribosyl ation of protein IDRs two case studies in PTM dependent modulation of biomolecular condensatesMichael Nosella Hospital for Sick Children University of Toronto Canada10 45 11 15Internal Structure of Chromatin CondensatesMike Rosen The University of Texas Southwestern Medical Center USA11 15 13 00Session 3 Protein structure in the condensed stateChair Janosch Hennig EMBL Heidelberg Germany11 15 11 45Decoding molecular plasticity in the dark proteomeEdward Lemke Johannes Gutenberg University Mainz Institute of Molecular Biology IMB GermanyNot available on demand11 45 12 00A multiscale model of PopZ condensationKeren Lasker The Scripps Research Institute USANot available on demand12 00 12 15Lightning Condensates the electrochemical functions of biomolecular condensatesYifan Dai Washington University in St Louis USANot available on demand12 15 12 30Structural reorganization underlying yeast cytoplasmic solidificationMarie Christin Spindler EMBL Heidelberg Germany12 30 13 00Complex coacervation of highly charged IDPsBen Schuler University of Zurich SwitzerlandNot available on demand13 00 14 30Lunch and meet the editors14 30 16 45Session 4 Condensates and RNAChair Simon Alberti Technische Universit t Dresden Germany14 30 15 00Multiphase behavior of the nucleolus throughout the C elegans life cycleStephanie Weber McGill University Canada15 00 15 15Germ granule higher order organization coordinates their different functionsAli Haidar Institute of Human Genetics IGH University of Montpellier France15 15 15 30Multiscale multiphase condensates buffers mRNA variations to promote robust mRNA protein stoichiometryAmira Ouertani Universit C te D Azur CNRS Inserm iBV France15 30 16 00Coffee break and meet the speakers16 00 16 15Cold Induced Phase Separation of a Chloroplast RNAbinding proteinChristian Schmitz Linneweber Humboldt University Berlin Germany16 15 16 30Biomolecular condensates enable complex cellmorphology through localized translationZachary Geisterfer Duke University United States of America16 30 16 45TAF2 condensation in nuclear speckles links basal transcription factor TFIID to RNA splicingTanja Bhuiyan University of Freiburg Germany16 45 17 15Flash talk Session 2 73 Aritra Chowdhury 86 Nadia Erkamp 104 Marcos Gil Garcia 116 Clara Hipp 170 Ambuja Navalkar 176 Mihajlo Novakovic 198 Aleksandra Sergeeva 216 Laura Thomas 226 S ren von B low 240 Tianjin Yang17 15 18 45Poster Session 2 even numbers 18 45 20 30Dinner in Canteen 20 30 22 00After dinner drinks in ATC Foyer Day 3 Thursday 16 May 2024 Time Europe Berlin Speaker09 00 12 00Session 5 Condensates in cellular quality controlChair Dorothee Dormann Johannes Gutenberg University Mainz Germany09 00 09 30SUMO2 3 conjugation of TDP 43 protects against aggregationSerena Carra University of Modena and Reggio Emilia Italy09 30 09 45PARP1 DNA co condensation drives DNA repair site assembly to prevent disjunction of broken DNA endsNagaraja Chappidi Technische Universit t Dresden Germany09 45 10 00TERRA LSD1 phase separation promotes R loop formation for telomere maintenance in ALT cancer cellsHuaiying Zhang Carnegie Mellon University USA10 00 10 30Coffee break and meet the speakers10 30 11 00Sequence programmable nucleic acid condensatesAnkur Jain Whitehead Institute for Biomedical Research USA11 00 11 15Not just passive Active PKA inside stress granule regulates their maturation for the timely recovery after stressSonja Kroschwald ETH Zurich Switzerland11 15 11 45Regulation of stress induced condensates and their role in cell healthHyun Kate Lee University of Toronto Canada11 45 12 00PDIA6 condensates regulate ER stress signalingAnna Leder University of Basel Switzerland12 00 13 30Lunch13 30Free afternoon14 15 15 45Optional Guided City Tour of Heidelberg Registration onsite limited capacity available Meeting Point is Neckarm nzplatz Day 4 Friday 17 May 2024 Time Europe Berlin Speaker09 30 12 00Session 6 Condensates in gene expressionChair Sina Wittmann Institute of Molecular Biology Germany09 30 10 00The role of stress induced nuclear condensates of NELF in organismal physiologyRitwick Sawarkar University of Cambridge UK10 00 10 15Spatially controlled phase separation of MYC proteins as oncogenic principleMartin Eilers University of W rzburg GermanyNot available on demand10 15 10 30HP1a mediates chromatin miscibility in vitro driving spontaneous and reversible heterochromatin compartmentalizationLucy Brennan University of California Berkeley USA10 30 11 00Coffee break and meet the speakers11 00 11 15Stress granules reinforce the translation program of the integrated stress responseJarrett Smith Whitehead Institute USA11 15 11 45DEAD Box ATPases as regulators of RNA containing membraneless organellesMaria Hondele University of Basel SwitzerlandNot available on demand11 45 12 00Dissecting the contributions of D E tracts to setting up nucleolar pH gradients and complexities of complex coacervationMatthew King Washington University in St Louis USA12 00 14 00Lunch14 00 16 30Session 7 Emerging technologiesChair Julia Mahamid EMBL Heidelberg Germany14 00 14 30Molecular mechanisms of protein phase separationTuomas Knowles University of Cambridge UK14 30 14 45Systematic identification of condensate targets and development of condensate modifying drugs across therapeutic areasAvinash Patel Dewpoint Therapeutics USA14 45 15 00The phase separation landscape of genome wide genetic perturbationsMeta Heidenreich Weizmann Institute of Science Israel15 00 15 15Short linear motifs as condensation switchesSteven Boeynaems Baylor College of Medicine USANot available on demand15 15 15 45Coffee break and meet the speakers15 45 16 15Form and function in biomolecular condensationYongdae Shin Seoul National University Korea16 15 16 30Spatiotemporal control of chromatin associated condensate nucleationWilliam Jacobs Princeton University USA16 30 17 30Keynote lecture From physics to biology and back again How physical understanding of condensate properties can explain biological function and disease processesTanja Mittag St Jude Children s Hospital USA17 30 17 45Feedback Survey Session Q A 17 45 18 00Closing remarks and Poster prize18 00 20 00Conference Dinner in Canteen20 00 23 00Conference Party Practical information Registration fees and abstract submission On site registration fees include admission conference materials meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Virtual registration fees include access to all of the talks livestreamed and on demand and facility to submit questions On site Academia 725On site PhD Student 625On site Industry 925On site Journal Editor 300Virtual Academia 225Virtual PhD Student 175Virtual Industry 275 Editors from scientific journals are allowed to attend at a reduced rate but asked to contribute to the conference in return by taking part in meet the editors sessions or other planned activities within the programme A letter to support your visa application will be issued on request once payment of the registration fee is confirmed We recommend that you book your visa appointment as soon as possible to avoid any delay with your visa application Accredited journalists may be eligible to register for complimentary press registration Registrants may be required to provide accreditation or equivalent proof of press membership after registration Please contact Sophie Dutzi for more information Please note that we do not offer complimentary registrations for editors of scientific journals Confirmation and payment Registration will be on a first come first served basis Your place can only be confirmed after payment of the registration fee If you are added to our waiting list please consider taking advantage of our offerings to participate virtually On site participants Types of payments accepted are international bank transfers and credit card payments Virtual participants We are only able to accept card payments In exceptional cases we can accept bank transfers Please contact events embl de for details Abstract submission Only participants registering to attend the on site event are eligible to submit an abstract Abstracts will not be accepted from virtual participants After registration you can submit your abstract via a separate link that will be provided in the email confirmation Alternatively you can access the link on the confirmation page directly after registering The same login credentials are used for both processes Please note Abstract body The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised Title The title should not exceed 20 words Only the first word of the title should start with a capital letter and the rest should be lowercase Authors and affiliations Please fill in the author s details as requested in the online form The compulsory fields are First Name Last Name Organisation Name Affiliation or Company Country and Email Kindly mark only one author in the role of First Author and please don t forget to indicate who will be the Presenter Please enter your co authors correctly via the system by adding accounts together with their organisation institute Do not copy paste them into the body of the abstract text as they will not be indexed in the abstract book Presentation types When submitting your abstract you can apply for an oral or poster presentation A selection process will take place with the results announced 2 3 weeks after the abstract submission deadline For detailed instructions on how to submit a conference abstract follow the instructions provided in this video Please check our FAQs pages for further information on how to submit an abstract Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of registration fee waivers travel grants and childcare grants Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course or conference Travel grant The travel grant will cover the cost of travel to an on site event airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from within Europe up to 1000 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from outside Europe up to 500 for any participant travelling to an EMBO Workshop up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Workshop up to 700 for any participant working in Croatia Czech Republic Estonia Greece Hungary Italy Lithuania Luxembourg Poland Slovenia and Turkey travelling to an EMBO Workshop Registration fees are only covered for EMBO Workshops The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant There is the possibility to apply for a childcare grant to offset child care costs incurred by participants speakers and organisers when attending a conference Eligible costs include but are not limited to fees for a baby sitter or child care facility and travel costs for a caregiver Please note that priority will be given to early stage researchers In order to apply for this grant you must be registered by the abstract submission deadline There is a limited amount of funding available for the childcare grants and funds will be distributed amongst eligible applicants Application On site participants You may apply for financial assistance when submitting your abstract In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Virtual participants If you are attending virtually you can apply for financial assistance in the submission portal by the abstract deadline Read the instructions on how to apply for financial assistance Only submissions for financial assistance will be accepted Presentation abstracts cannot be submitted here and will be declined In your application you will be asked to summarise your current work answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Selection The scientific organisers will select the recipients of all financial assistance during the abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection for registration fee waivers and travel grants is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Childcare grants will be allocated in the same timeframe 6 8 weeks before the event start date Please note that priority will be given to early stage researchers Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details View our list of external funding opportunities and information on attending a conference as an event reporter For further information about financial assistance please refer to the FAQ page Accommodation and travel Accommodation is not included in the conference registration fee As further changes in our events are possible you should book flights trains and hotels with flexible options and favourable cancellation conditions The hotels below have rooms on hold for participants until 16 April 2024 in some cases at special rates Please email the hotel directly quoting the booking code EES24 06 to confirm the exact price of the room Hotel AnlageHilton HeidelbergHotel MonptiB B HotelHotel Holl nder Hof Premier Inn Heidelberg CityHotel Bayrischer Hof Hotel ibis HeidelbergHotel Vier Jahreszeiten HeidelbergExzellenz HotelLeonardo Hotel Heidelberg City Centre Travel information For travel information please see here If you are travelling to the conference within Germany then you are eligible for the Deutsche Bahn Event Ticket called the Veranstaltungsticket in German This will result in a lower ticket price if your travel distance to Heidelberg is more than 100 km You need to provide proof of your event attendance when purchasing the ticket For more information in English see here or in German see here You can book your ticket here Conference shuttle buses Conference shuttle buses are free of charge for participants and depart from designated bus stops near the hotels to EMBL and back mornings and evenings The bus stops for this conference are Hotel Staycity Speyerer Str 7 Kurf rsten Anlage Opposite Main Train Station Hotel Premier Kurf rsten Anlage 23 Leonardo Hotel Heidelberg City Center Bergheimer Str 63 Neckarmuenzplatz Heidelberg Tourist Information Peterskirche Bus stop ISG Hotel Im Eichwald 19 Conference shuttle bus schedule View Conference shuttle bus stops and hotels in a larger map Please note that not every bus stop will be used for every event Further details Address EMBL Meyerhofstra e 1 69117 Heidelberg Germany For more information about accommodation and travel please refer to the FAQ page Onsite information Catering All meals and coffee breaks are included in the registration fee Our catering staff will prepare a wide variety of vegetarian meals meat and fish dishes soups pasta fresh fruit and vegetables as well as a variety of desserts Please wear your badge at all times when serving yourself No food or drinks are allowed in the auditorium Charging lockers There are lockers available next to the stairs leading down into the Auditorium You will find some of those equipped with sockets to charge your smartphone tablet etc Electricity and charging station In most places the electricity is 220 volts AC 50 cycles An adaptor and a plug that fits the German socket may be needed for your appliances laptop i e American Japanese etc A USB charging station for electronic devices is available at the registration desk EMBL merchandise If you are interested in purchasing EMBL merchandise products presented in the glass display in the registration area please email the EMBL shop to place an order or get in contact with your Course Organiser Kindly note the EMBL shop is only open upon request and all purchases must be made in cash Euros only Health and safety notes Please read EMBL s COVID 19 safety policy for on site events Do not smoke in any EMBL building Eating and drinking is prohibited in the Auditorium and all laboratories Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required The first aid room is located next to the ATC Registration Desk room 10 205 Dial the Emergency number 222 from any EMBL internal phone only Where is the accident What happened How many injured Emergency number 06221 387 7821 from mobile phones Please report all accidents to the conference officer at the registration desk In case of fire Press the nearest fire alarm button or the Emergency number 222 from any internal phone A loud fire alarm will go off if an evacuation is required On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting points Do not use the lifts Beyond first aid Please remember to bring your own medication if needed to the conference Note that the next pharmacy is a 4 minute drive from the EMBL but for many medications you will be required to see a doctor to get a prescription Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg In any case the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary Internet Wi Fi is available on campus using the EMBL Events network and the event specific password which will be provided on site The eduroam network secure worldwide roaming access service developed for the international research and education community is also available Lost and found Lost and Found items are kept at the registration desk until the end of the conference Luggage There are lockers available on site to store your luggage which require a 2 EURO coin to operate There is another luggage room on level E0 which is free to use but remains unlocked during the conference Nursing room There is a nursing room available in the ATC Rooftop Lounge on level A29 Photography During the conference an EMBL Photographer may be taking photos If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Printing We can help to print your boarding pass train ticket Please send it to events embl de and collect your print outs at the registration desk Room for prayer yoga and meditation There is a room for prayer meditation and yoga located on level E0 behind the Auditorium Please be respectful of others using the room Sightseeing A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing Travel to and from the venue During the event we provide conference shuttle buses to and from EMBL In addition there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time Information on the conference shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page Useful German expressions HelloHalloGoodbyeAuf Wiedersehen formal Tsch ss informal Good morningGuten MorgenGood afternoonGuten TagGood eveningGuten AbendGood nightGute NachtI m sorryEs tut mir leidExcuse me Entschuldigen SieHow are you Wie gehts I m fine thanks And you Mir geht es gut danke Und Dir Ihnen What is your nameWie hei en Sie formal Wie hei t du informal My name is Ich hei e Do you speak EnglishSprechen Sie englisch I don t understandIch verstehe nichtPlease speak more slowlyK nnen Sie bitte langsamer sprechenThank youDankesch nWhere is the toilet Wo ist die Toilette Please call me a taxiBitte rufen Sie mir ein TaxiHow do I get to Wie komme ich zum zur A beer two beers pleaseEin Bier zwei Bier bitteA glass of red white wine pleaseEin Glas Rot Wei wein bitteThe menu pleaseDie Speisekarte bitteIs there a local speciality Gibt es eine Spezialit t aus dieser Gegend I m vegetarianIch bin VegetarierIt was deliciousEs war hervorragendThe bill pleaseDie Rechnung bitteI have a headacheIch habe KopfschmerzenI have a sore throatIch habe HalsschmerzenMy stomach hurtsIch habe MagenschmerzenI m allergic toIch bin allergisch gegenI need a doctor who speaks English Ich brauche einen Arzt der englisch spricht Virtual participation What s included Access to all the livestreamed talks Video library of the recorded talks during the event and for two weeks afterwards Please note at the request of individual speakers some talks are not recorded Facility to submit questions Please note that only on site participants are able to submit abstracts and participate in the poster sessions Event platform We are using an event platform for this conference More information about the platform will be shared ahead of the conference Guidelines Do not broadcast the conference to unregistered participants You are encouraged to tweet and post about the event Tweet unless the speaker specifically says otherwise but be mindful of unpublished data Please do not capture transmit or redistribute data presented at the meeting Additional information can be found in our Code of Conduct Health and well being It is important to stay healthy and move around especially when you are attending an event virtually We have put together a few coffee break stretches and yoga videos in the conference platform for you to enjoy during the event How to ask questions Please use the Q A function in the event platform If you have any other questions you can go to the Help Desk in the event platform Click on more on the top menu and click Help Desk Time zone The programme is planned based on the Europe Berlin time zone unless otherwise stated Please take your time zone into consideration when planning your attendance COVID 19 related questions COVID 19 information for onsite events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Gold sponsor Bronze sponsor Event supporter Media partners EMBO Reports an EMBO Press journal FEBS Letters FEBS Open Bio International Union of Biochemistry and Molecular Biology Journal of Cell Science The Company of Biologists Journal Medinformatics a Bon View Publishing journal Open Biology a Royal Society journal PLOS Biology a PLOS journal Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de Instrument contest Labbot a Gold sponsor of the EMBO EMBL Symposium Cellular Mechanisms Driven by Phase Separation invites participants to submit their innovative research proposals for a chance to win a Labbot instrument valued at 49 000 Entries will be evaluated based on their creativity and potential impact in the field The submission process is straightforward requiring a simple registration and a concise project description The deadline for submissions is 16 May before 17 00 Winners will be announced on site on 17 May following the closing remarks For a summary of the contest and detailed instructions on how to participate please click on the link below Download contest description About EMBO EMBL Symposia promote scientific communication and collaboration in the European research area They provide scientists with a platform to discuss and exchange ideas on forward looking topics and new developments in the life sciences Topics emphasise upcoming developments and the interdisciplinary nature of related fields Jointly funded and organised by EMBO and EMBL and complementary to their respective courses workshops and conference programmes the symposia promote scientific communication and collaboration All symposia are held in the EMBL Advanced Training Centre ATC in Heidelberg Germany or virtually Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9 Leaderboard 728 90...

Simon Alberti, Sara Cuylen-Häring, Dorothee Dormann, Alex Holehouse

EMBO | EMBL Symposium

EMBL Heidelberg, Virtual

14 May - 17 May 2024

Introduction to metabolomics analysis

Edit

May 14, 2024 00:002024CourseEMBL-EBI

Meredith Willmott

EMBL-EBI

12 May - 17 May 2024

Advanced fluorescence imaging techniques

Edit

May 12, 2024 00:002024CourseEMBL Heidelberg

Description OverviewSpeakersProgrammePractical informationSponsorsMedia Kit Overview Course overview This practical course will cover advanced light microscopy techniques and participants will learn how to derive qualitative and quantitative insights on molecular mechanisms in cells and developing organisms Invited guest researchers together with microscopy experts from EMBL will foster an intense information flow with a balance of lectures and practical workshops The focus of the course will be on the use of fluorescence microscopy to obtain information about localisation and functions of proteins and other bio molecules at different spatial scales Audience This course is directed towards researchers in the life sciences with access to light microscopy equipment who have an immediate need to apply the techniques they will learn to solve biological problems at the cellular and molecular level in vivo As the course will be primarily focused on the advanced techniques we expect participants to have basic knowledge of light microscopy This course is organised in cooperation with Evident Modules Resources The topics will include fluorescence microscopy techniques such as fast time lapse microscopy of living cells spinning disk and point scanning confocal microscopy of large 3D samples photo manipulation as a tool multicolour single molecule localization microscopy SMLM with spectral demixing expansion microscopy FRET based techniques For demanding applications we will cover the aspects of image processing and analysis and the possibilities of microscope automation The modules will cover all necessary knowledge and demonstrate tools to conduct similar pipelines at your home lab enabling you to answer emerging biological questions Learning outcomes Get an overview of advanced fluorescence imaging techniques Obtain hands on experience setting up and running advanced experiments on modern fluorescence microscopes Discuss the possibilities and drawbacks of experiment planning and data interpretation with experts in the field This course is kindly supported by the EMBL Advanced Light Microscopy Facility This course is organised in cooperation with Evident What past participants say I highly recommend this course if you are looking to take your fluorescence microscopy experiments to the next level Josefina Marin Rojas Universidad de Chile Chile Speakers Speakers trainers and staff Yannick Nossin CellSignal The Netherlands Ipek Altinoglu Abbelight France Benjamin Compans Abbelight France Joana Delgado Martins University of Zurich Switzerland Claire Deo EMBL Heidelberg Germany Manuel Alexander Peter Gunkel EMBL Heidelberg Germany Aliaksandr Halavatyi EMBL Heidelberg Germany Mark Hink University of Amsterdam Netherlands Viktor Jakob Evident Germany Robert Kasper Evident Germany Muzamil Khan EMBL Heidelberg Germany Simone K hler EMBL Heidelberg Germany Marko Lampe EMBL Heidelberg Germany Stefan Marawske Evident Germany Felix Mikus EMBL Heidelberg Germany Kaarjel Narayanasamy EMBL Heidelberg Germany Pedro Pereira ITQB NOVA Portugal Marianna Poli Euro Bioimaging Germany Markus Sauer University of W rzburg Germany Stefan Terjung EMBL Heidelberg Germany Nikita Vladimirov University of Zurich Switzerland Urs Ziegler University of Zurich Switzerland Anja Zimmermann Rapp OptoElectronic GmbH Germany Scientific organisers Joana Delgado Martins University of Zurich Switzerland Aliaksandr Halavatyi EMBL Heidelberg Germany Stefan Marawske Evident Germany Course organisers Luana Ribeiro Course and Conference Officer EMBL Heidelberg Germany Swetlana Krez Scientific Training Officer EMBL Heidelberg Germany Programme Programme Day 1 Sunday 12 May 2024 Time Europe Berlin SpeakerLocation15 30 16 00RegistrationISG Hotel Seminar Room Weimar16 00 16 30WelcomeISG Hotel Seminar Room Weimar16 30 19 00Flash talks by participantsISG Hotel Seminar Room Weimar19 00 21 00DinnerISG Hotel Day 2 Monday 13 May 2024 Time Europe Berlin SpeakerLocation08 35Bus from ISG Hotel to EMBLHotel entrance08 55 09 00EMBL introduction house notes and lab safetyCourtyard Room A B09 00 10 00Lecture Q A Concepts in Light microscopyUrs Ziegler University of Zurich SwitzerlandCourtyard Room A B10 00 11 00Lecture Q A DIY super resolution Expanding biology above diffractionPedro Matos Pereira ITQB PortugalCourtyard Room A B11 00 11 20Coffee BreakCourtyard Room A B11 20 12 05Lecture Q A Multimodal imaging driven insight into pulmonary fibrosis from model system to drug discoveryMuzamil Khan EMBL Heidelberg GermanyCourtyard Room A B12 05 12 30Lecture Q A Specificity is key A Spotlight on Cell Signaling Technology innovative solutions in multiplex IHCYannick Nossin CellSignal The NetherlandsCourtyard Room A B12 30 13 30LunchEMBL Canteen13 30 16 00Hands on practical 1 Live cell imagingJoana Delgado University of Zurich SwitzerlandUrs Ziegler University of Zurich Switzerland Groups 1 2 3D imaging of model organisms with CLSMStefan Terjung EMBL Heidelberg GermanyStefan Marawske Evident Germany Groups 3 4 Microscopy rooms 116 11716 00 16 15Coffee breakCourtyard Room A B16 15 18 45Hands on practical 2 3D imaging of model organisms with CLSM Stefan Terjung EMBL Heidelberg Germany Stefan Marawske Evident Germany Groups 1 2 Live cell imaging Joana Delgado University of Zurich Switzerland Urs Ziegler University of Zurich Switzerland Groups 1 2 Microscopy rooms 116 117Computer Training Lab18 45 19 45DinnerEMBL Canteen19 45Bus to HotelATC Entrance Day 3 Tuesday 14 May 2024 Time Europe Berlin SpeakerLocation08 35Bus from ISG Hotel to EMBLHotel entrance09 00 09 50Lecture Q A Adaptive Feedback MicroscopyAliaksandr Halavatyi EMBL Heidelberg GermanyCourtyard Room A B09 50 10 50Lecture Q A Visualizing chromosomes during meiosis Simone K hler EMBL Heidelberg GermanyCourtyard Room A B10 50 11 10Coffee breakCourtyard Room A B11 10 11 30Lecture How Euro BioImaging can support your research with access to the best imagingMarianna Poli Euro Bioimaging11 30 12 20Practical Setting and debugging adaptive feedback microscopy pipelinesManuel Gunkel EMBL Heidelberg GermanyComputer training lab12 20 13 15LunchEMBL Canteen13 15 13 30Group Photo13 30 16 00Hands on practical 3 Applying adaptive feedback microscopy for high throughput photoactivation of specific cell phenotypesAliaksandr Halavatyi EMBL Heidelberg GermanyManuel Gunkel EMBL Heidelberg Germany Group 1 Deciphering Spatial Patterns The Crucial Where in Multiplexed Immunofluorescence within Patient Tissues Muzamil Khan EMBL Heidelberg Germany Yannick Nossin CellSignal The Netherlands Group 2 DeconvolutionUrs Ziegler University of Zurich Switzerland Group 3 4 Microscopy rooms 116 11716 00 16 15Coffee breakCourtyard Room A B16 15 18 45Hands on practical 4 Applying adaptive feedback microscopy for high throughput photoactivation of specific cell phenotypes Aliaksandr Halavatyi EMBL Heidelberg Germany Manuel Gunkel EMBL Heidelberg Germany Groups 3 Deciphering Spatial Patterns The Crucial Where in Multiplexed Immunofluorescence within Patient Tissues Muzamil Khan EMBL Heidelberg Germany Yannick Nossin CellSignal The Netherlands Group 4 Deconvolution Urs Ziegler University of Zurich Switzerland Groups 1 2 Computer training labMicroscopy rooms 116 11718 45 20 00Pizza dinner and informal discussionCourtyard rooms20 00Bus to HotelATC entrance Day 4 Wednesday 15 May 2024 Time Europe Berlin SpeakerLocation08 35Bus from ISG Hotel to EMBLHotel entrance09 00 09 45Lecture Q A Introduction to SMLM from concepts to samples Benjamin Compans Abbelight FranceCourtyard Room A B09 45 10 45Lecture Q A Measuring interactions and biosensors using FRETMark Hink University of Amsterdam The NetherlandsCourtyard Room A B10 45 11 15Coffee break11 15 12 30Practical Preparation of expansion microscopy samplesPedro Matos Pereira ITQB PortugalTraining Lab12 30 13 30LunchEMBL Canteen13 30 16 00Hands on practical 5Multicolor Single molecule Localization Microscopy with Spectral Demixing Benjamin Compans Abbelight France Group 2 Deciphering Spatial Patterns The Crucial Where in Multiplexed Immunofluorescence within Patient Tissues Muzamil Khan EMBL Heidelberg Germany Yannick Nossin CellSignal The Netherlands Group 1 FRET Mark Hink University of Amsterdam The Netherlands Group 4 Imaging expanded samples Pedro Matos Pereira ITQB Portugal Group 3 Microscopy rooms 116 11716 00 16 15Coffee breakCourtyard Room A B16 15 18 45Hands on practical 6 Deciphering Spatial Patterns The Crucial Where in Multiplexed Immunofluorescence within Patient Tissues Muzamil Khan EMBL Heidelberg Germany Yannick Nossin CellSignal The Netherlands Group 3 Multicolor Single molecule Localization Microscopy with Spectral Demixing Benjamin Compans Abbelight France Group 4 Imaging expanded samples Pedro Matos Pereira ITQB Portugal Group 1 FRET Mark Hink University of Amsterdam The Netherlands Group 2 Microscopy rooms 116 11718 45 19 30Bus to dinner downtownATC entrance19 30 Dinner downtownGasthaus Zum Roten Ochsen Day 5 Thursday 16 May 2024 Time Europe Berlin SpeakerLocation08 35Bus from ISG Hotel to EMBLHotel entrance09 00 10 00Lecture Q A The Benchtop mesoSPIM a facility grade open source microscope for large cleared samples Nikita Vladimirov University of Zurich SwitzerlandCourtyard Room A B10 00 11 00Lecture Q A Small molecule fluorophores for biological imaging Claire Deo EMBL Heidelberg GermanyCourtyard Room A B11 00 11 30Coffee breakCourtyard Room A B11 30 12 30Lecture Q A True molecular resolution imaging Fluorescence imaging with a spatial resolution in the one digit nanometer range Markus Sauer University of W rzburg GermanyCourtyard Room A B12 30 13 30LunchEMBL Canteen13 30 16 00Hands on practical 7 FRET Mark Hink University of Amsterdam The Netherlands Group 3 Imaging expanded samples Pedro Matos Pereira ITQB Portugal Group 4 Applying adaptive feedback microscopy for high throughput photoactivation of specific cell phenotypes Aliaksandr Halavatyi EMBL Heidelberg Germany Manuel Gunkel EMBL Heidelberg Germany Group 2 Multicolor Single molecule Localization Microscopy with Spectral Demixing Benjamin Compans Abbelight France Group 1 Microscopy rooms 116 11716 00 16 30Visit to The World of Molecular Biology ExhibitionImaging Center16 30 19 00Hands on practical 8 Imaging expanded samplesPedro Matos Pereira ITQB Portugal Group 2 FRET Mark Hink University of Amsterdam The Netherlands Group 1 Multicolor Single molecule Localization Microscopy with Spectral Demixing Benjamin Compans Abbelight France Group 3 Applying adaptive feedback microscopy for high throughput photoactivation of specific cell phenotypes Aliaksandr Halavatyi EMBL Heidelberg Germany Manuel Gunkel EMBL Heidelberg Germany Group 4 Microscopy rooms 116 11719 00 20 00DinnerEMBL Canteen20 00 21 00Informal Q A discussion and drinksCourtyard Room A B21 00Departure to HotelATC entrance Day 6 Friday 17 May 2024 Time Europe Berlin SpeakerLocation08 35Bus from ISG Hotel to EMBLHotel Entrance09 00 10 30Practical FRET data analysisMark Hink University of Amsterdam The NetherlandsComputer training lab10 30 11 00Coffee breakoutside Computer training lab11 00 12 30Practical SMLM data analysisMarko Lampe EMBL Heidelberg GermanyComputer training lab12 30 13 30LunchEMBL Canteen13 30 14 40Preparation of student presentationsComputer training lab14 40 16 00Student presentationsComputer training lab16 00 16 30Wrap up of course and departureComputer training lab16 30Bus to ISG Hotel Heidelberg train station and city centerATC entrance Practical information Registration fees and motivation letter The course is limited to 16 participants For selection purposes please note that your application will not be considered without a letter of motivation Registration Registration fees include admission course materials meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Academia 625PhD Student 625Industry 1150 A letter to support your visa application will be issued on request once payment of the registration fee is confirmed We recommend that you book your visa appointment as soon as possible to avoid any delay with your visa application Confirmation and payment The registration fee should be paid only after acceptance to the course The results will be announced approximately 2 3 weeks after the application deadline Motivation letter submission After you have logged in and successfully registered you will receive an email asking you to submit your motivation letter Click on the link provided and enter your motivation letter in the text box provided Alternatively you can submit your motivation letter by clicking on the link on the confirmation page directly after registering Instructions Include your relevant skills experience and qualifications showing why you would be suitable for the course Explain why you would like to attend including what you can contribute and how you think you will benefit from the course Please note The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised For detailed instructions please watch our video on how to submit a course motivation letter Further details For further information about registration and motivation letter submission please refer to the FAQ page Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of registration fee waivers travel grants and childcare grants Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course Travel grant The travel grant will cover the cost of travel airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Course within Europe up to 1000 for participants travelling to an EMBL Course from outside Europe up to 500 for any participant travelling to an EMBO Practical Course up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Practical Course up to 700 for any participant working in Croatia Czech Republic Estonia Greece Hungary Italy Lithuania Luxembourg Poland Slovenia and Turkey travelling to an EMBO Practical Course Registration fees are only covered for EMBO Practical Courses The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant There is the possibility to apply for a childcare grant to offset child care costs incurred by participants speakers trainers and organisers when attending a course Eligible costs include but are not limited to fees for a babysitter or child care facility and travel costs for a caregiver Please note that priority will be given to early stage researchers There is a limited amount of funding available for the childcare grants and funds will be distributed amongst eligible applicants Boehringer Ingelheim Fonds travel grant Applies to selected courses only Availability will be indicated during the motivation letter submission process This grant covers costs related to your attendance at the course registration travel and accommodation costs The grant is restricted to PhD students and postdocs who conduct basic biomedical research Whether you are eligible to apply for a travel grant depends on when you received your university entrance qualification e g Abitur A Levels High School Diploma Final State Examination for PhD and MD students as well as graduates the university entrance qualification must not have been obtained more than 11 years ago at the time of the envisaged course for postdocs the university entrance qualification must not have been obtained more than 13 years ago at the time of the envisaged course Application You may apply for financial assistance when submitting your motivation letter for courses In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application For the Boehringer Ingelheim Fonds Travel Grant there is a pre application question during the motivation letter submission process and if selected you will be requested to complete a standard form and documentation consisting of your travel expense estimation Selection The scientific organisers will select the recipients of registration fee waivers and travel grants during the motivation letter or abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection for registration fee waivers and travel grants is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Childcare grants will be allocated in the same timeframe 6 8 weeks before the event start date Please note that priority will be given to early stage researchers Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details See our list of external funding opportunities and for further information about financial assistance please refer to the FAQ page Accommodation and travel Travel information For travel information please see here If you are travelling to the conference within Germany then you are eligible for the Deutsche Bahn Event Ticket called the Veranstaltungsticket in German This will result in a lower ticket price if your travel distance to Heidelberg is more than 100 km You need to provide proof of your event attendance when purchasing the ticket For more information in English see here or in German see here You can book your ticket here Hotel Accommodation is not included in the registration fee Participants are expected to book and pay for their own accommodation A mix of single and twin rooms have been reserved for 5 nights 12 17 May 2024 at ISG Hotel Single rooms are limited and will be available on a first come first served basis After the selection process selected participants should contact the hotel directly to make a booking with the booking code MIC24 02 by the deadline of 14 April 2024 We recommend that all course participants stay in the dedicated hotel for the course Local transport Shuttle buses will go from the ISG Hotel to EMBL and back mornings and evenings A bus schedule and location of the bus stops will be made available prior to the meeting Further details Address EMBL Heidelberg Meyerhofstra e 1 69117 Heidelberg GermanyFor more information about accommodation and travel please refer to the FAQ page On site information Catering All meals and coffee breaks are included in the registration fee Our catering staff will prepare a wide variety of vegetarian meals meat and fish dishes soups pasta fresh fruit and vegetables as well as a variety of desserts Please wear your badge at all times when serving yourself No food or drinks are allowed in the laboratories Electricity and charging station In most places the electricity is 220 volts AC 50 cycles An adaptor and a plug that fits the German socket may be needed for your appliances laptop i e American Japanese etc A USB charging station for electronic devices is available at the registration desk EMBL Merchandise If you are interested in purchasing EMBL merchandise products presented in the glass display in the registration area please email the EMBL shop to place an order or get in contact with your Course Organiser Kindly note the EMBL shop is only open upon request and all purchases must be made in cash Euros only Health and safety notes Please read EMBL s COVID 19 safety policy for on site events Do not smoke in any EMBL building Eating and drinking is prohibited in all laboratories Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required The first aid room is located next to the ATC Registration Desk room 10 205 Dial the Emergency number 222 from any EMBL internal phone only Where is the accident What happened How many injured Emergency number 06221 387 7821 from mobile phones Please report all accidents to the conference officer at the registration desk In case of fire Press the nearest fire alarm button or the Emergency number 222 from any internal phone A loud fire alarm will go off if an evacuation is required On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting points Do not use the lifts Beyond first aid Please remember to bring your own medication if needed to the conference Note that the next pharmacy is a 4 minute drive from the EMBL but for many medications you will be required to see a doctor to get a prescription Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg In any case the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary Internet Wi Fi is available on campus Log in using the EMBL Events network and the event specific password which will be provided on site The eduroam network secure worldwide roaming access service developed for the international research and education community is also available Lost and found Lost and Found items are kept at the registration desk until the end of the conference Luggage There are lockers available on site to store your luggage which require a 2 EURO coin to operate There is another luggage room on level E0 which is free to use but remains unlocked during the conference Nursing room There is a nursing room available in the ATC Rooftop Lounge on level A29 Photography During the conference an EMBL Photographer may be taking photos If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Printing We can help to print your boarding pass train ticket Please send it to events embl de and collect your print outs at the registration desk Room for prayer yoga and meditation There is a room for prayer meditation and yoga located on level E0 behind the Auditorium Please be respectful of others using the room Sightseeing A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing Travel to and from the venue During the event we provide conference shuttle buses to and from EMBL In addition there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time Information on the shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page Map to walk from ISG Hotel to EMBL Additional information Address EMBL Heidelberg Meyerhofstra e 1 69117 Heidelberg Germany ATC orientation map Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page Technical requirements and event software Event software The EMBL eCampus learning platform will be used to collaborate communicate and network with all of the course participants All participants will receive information on how to join shortly before the course We recommend using Chrome Safari or Mozilla Firefox browsers for eCampus Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page COVID 19 related questions COVID 19 information for on site events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Event Partners Event Sponsors Media partners Imaging and Microscopy a Wiley magazine Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other events or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de Media Kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9...

Manuel Gunkel, Aliaksandr Halavatyi, Debora Keller-Olivier Joana Delgado Martins, Irina Rakotoson

EMBL Course

EMBL Heidelberg

9 May 2024

Exploring human disease and protein variant data in UniProtKB

Edit

May 09, 2024 15:302024WebinarVirtual

Description UniProt KnowledgeBase UniProtKB supports biomedical research by providing a comprehensive high quality and freely accessible resource of protein sequence and functional information This webinar will provide an overview on how to access human disease and protein variant information available in UniProtKB It will outline the annotation of protein molecular function involvement in human disease as well as disease associated variants including variant position variant characterisation and their impact on protein structure and function It will present the protein variant viewer and feature viewer and demonstrate how the feature viewer facilitates visualisation of variant impact on protein features and 3D structure We will discuss the cross links to human specific databases and tools such as BLAST and Align In addition we will also demonstrate how to access and download human variation datasets available in UniProtKB By the end of this webinar attendees will have a solid foundation in navigating UniProtKB to access disease related protein data and utilising the various protein molecular data to analyse the impact of protein variants on protein function and structure...

Virtual

8 May 2024

Wine yeasts as a model system in community ecology

Edit

May 08, 2024 15:302024WebinarVirtual

Description Wine fermentation constitutes a transient microbial ecosystem wherein numerous yeast species originating from the grape surface engage in interactions This leads to an ecological succession anticipated to culminate in the ultimate dominance of Saccharomyces cerevisiae The diversity of yeast species found in grape musts has a direct impact on the final chemical and aroma complexity of the resulting wines Understanding the molecular and ecological interaction patterns between wine yeast communities is essential to harness diverse yeast functionalities with the final aim of producing tailored high quality wines In this webinar we will introduce the expectable phylogenetic and functional diversity in wine yeast communities we will discuss how to engineer wine yeast communities top down and bottom up and we will finally conclude about the necessity of adopting the adequate theoretical framework to address challenging questions in applied ecology and to finally improve microbiome based industrial processes You may either watch the entire presentation from the introduction or navigate directly to a specific section by clicking the links provided below IntroductionFirst global map of vineyard microbiomeBuilding a wine yeast collectionProspecting non conventional yeastQ A...

Virtual

7 May - 9 May 2024

Open Virtual Ensembl Browser Workshop

Edit

May 07, 2024 00:002024CourseVirtual

Description Work with the Ensembl Outreach team to get to grips with the Ensembl browser accessing gene variation comparative genomics and regulation data and mine these data with BioMart...

Aleena Mushtaq

Virtual

6 May - 8 May 2024

Building networks 2024: engineering in vascular biology

Edit

May 06, 2024 00:002024ConferenceEMBL Barcelona

Description OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview This conference will take place at EMBL Barcelona Conference overview Blood vessels are essential for the formation and maintenance of larger tissues and organs The vascular system regulates exchange of oxygen nutrients and immune cells the dysfunction of which can cause severe pathologies Mouse models genetics and histology of human samples coupled with recent advances in imaging single cell approaches and computational modelling have provided significant knowledge to the field of vascular biology Yet in vivo models are highly complex and often need to be combined with simpler in vitro studies to get mechanistic and molecular insights Growth of in vitro blood vessels presents numerous research challenges due to their complex 3D geometry and a strong coupling between biology and mechanics Recent advances in microfluidic and 3D bioprinting offer a higher degree of control over design system components and biological function With the emergence and consolidation of these technologies together with human iPS cell technologies the vascular biology field is starting to model vascularized tissues and human vascular diseases in vitro In this meeting we intend to bring together vascular biologists and bioengineers from across the world to build research synergies to tackle long standing questions in the field of vascular biology Session topics Developmental vascular biology Vascular mechanobiology Aging in vascular biology Vascular integrity and thrombosis Vascular signaling and angiogenesis Lymphatics Vascular cardiobiology and engineering Speakers Keynote Speakers Christopher Chen Boston University USA Shulamit Levenberg Technion Israel Institute of Technology Israel Stefania Nicoli Yale University USA Speakers Irene Aspalter The Francis Crick Institute UK Abdul Barakat cole Polytechnique France Rui Benedito CNIC Spain Alexandre Dubrac University of Montreal Canada Maike Frye University Medical Center Hamburg Germany Kristina Haase EMBL Barcelona Spain Thomas Iskratsch Queen Mary University of London UK Anjali Kusumbe University of Oxford UK Riccardo Levato Utrecht University The Netherlands Tatiana Petrova University of Lausanne Switzerland Li Kun Phng RIKEN Center for Biosystems Dynamics Research Japan Shahin Rafii Weill Cornell USA Stefan Schulte Merker WWU M nster Germany Andy Shih Seattle Children s USA Virtual speaker Kelly Stevens University of Washington USA Oliver Stone University of Oxford UK Andries van der Meer University of Twente Netherlands Boyang Zhang McMaster University Canada Ying Zheng University of Washington USA Scientific Organisers Maria Bernabeu EMBL Barcelona Spain Cl udio Franco University of Lisbon Portugal Stephan Huveneers Amsterdam AMC Netherlands Milica Radisic University of Toronto Canada Conference Organisers Aline Schnieder EMBL Heidelberg Germany Silvia Autet Balcells EMBL Barcelona Spain Ina Grigorjeva EMBL Barcelona Spain Programme Are you on social media Post using EMBOBuildNetworks and don t forget to tag EMBLEvents Programme is preliminary and subject to change For registered participants recorded talks will be accessible on demand for 2 weeks after the end of the event unless indicated otherwise Day 0 Sunday 5 May 2024 Time Europe Barcelona 18 00Informal city tour optional Day 1 Monday 6 May 2024 Time Europe Barcelona Speaker09 00 09 45Registration and welcome coffee09 45 10 00Opening remarks by scientific organisers10 00 11 00Keynote lecture Engineering vasculature build learn repeatChristopher Chen Boston University USANot available on demandSession 1 Developmental vascular biologyChairs Claudio Franco and Li Kun Phng11 00 11 30Unraveling vascular development insights from single cell functional geneticsRui Benedito CNIC Spain11 30 11 45Reverse angiogenesis drives vascularization in distal lung budsMiram Meziane MIT Whitehead Institute USANot available on demand11 45 12 00Deep learning s journey through mouse retinal microscopy imagesHemaxi Narotamo Universidade Cat lica Portuguesa UCP Portugal12 00 12 30Engineering Kelly Stevens University of Washington USANot available on demand12 30 12 45Establishment of an in vitro morphogenetic process of non embedded endothelial self organization towards a lumenized capillaryAna Ximena Monroy Romero Universidad Aut noma de M xico Mexico12 45 14 15LunchFrom 13 15 concurrent lab tour Session 2 Vascular mechanobiologyChairs Christopher Chen and Stephan Huveneers14 15 14 45Endothelial mechano regulation in health and diseaseMaike Frye University Medical Center Hamburg Eppendorf GermanyNot available on demand14 45 15 00Primitive macrophages enhance a perivascular niche to enable vascular perfusion in human cardiac tissueShira Landau University of Toronto Canada15 00 15 15Forces mediate endothelial recruitment and reprogramming during CCM lesion growthApeksha Shapeti KU Leuven Belgium15 15 15 45Mechanical regulation of vascular smooth muscle cell phenotypic switching in arterial diseaseThomas Iskratsch Queen Mary University of London UK15 45 16 15Coffee break Meet the speakers16 15 16 45Light based bioprinting for perfusable engineered tissues and vascular modelsRiccardo Levato Utrecht University The NetherlandsNot available on demand16 45 17 00Biofabrication of perfusable and complex vascularization via sacrificial templating for tissue engineeringMatthias Ryma University of Bayreuth University Clinic W rzburg Germany17 00 17 30Combined forces of actin cytoskeleton and hydraulics in shaping blood vesselsLi kun Phng RIKEN Center for Biosystems Dynamics Research JapanNot available on demand17 30 18 00Flash talks 47 Roeland M H Merks 57 Hannah Fleckenstein 71 Aleksandra Kopacz 85 Fatemeh Mirzapour 89 L a Pinon18 00 20 00Poster session 1 odd numbers See the poster listing here Day 2 Tuesday 7 May 2024 Time Europe Barcelona Speaker07 00 08 00Group run optional 09 00 10 00Keynote lecture Localized multimerization of RNA sequences control cell migrationStefania Nicoli Yale University USASession 3 Aging in vascular biologyChair Tatiana Petrova10 00 10 30Optical dissection of brain capillary function Andy Shih Seattle Children s USA virtual speaker 10 30 10 45Human C peptide is a ligand of the elastin receptor complex and therewith central to vascular remodelling and disease in vascular agingGert Wensvoort Uit de Krempe IP BV The Netherlands10 45 11 15Vascular aging causes and consequencesAnjali Kusumbe University of Oxford UK11 15 11 45Coffee break meet the speakersSession 4 Vascular integrity and thrombosisChairs Maria Bernabeu and Andries van der Meer11 45 12 15Anatomical reconstruction of organ specific microvasculature and their applicationsYing Zheng University of Washington USA12 15 12 303D BBB a microfluidic model to investigate cellular and transcriptional changes after exposure to P falciparumLivia Piatti EMBL Barcelona12 30 12 45A fully iPSC derived human microfluidic 3D model of the blood brain barrier allows investigating mechanisms of neurovascular diseasesDominik Paquet University Hospital LMU Munich GermanyNot available on demand12 45 13 15In vitro blood vessels as platforms for studying vascular physiology and pathologyAbdul Barakat cole Polytechnique France13 15 14 45LunchFrom 13 45 concurrent lab tourSession 5 Vascular signaling and angiogenesisChairs Holger Gerhardt and Mariona Graupera14 45 15 15How to elect a leader Cellular decision making during sprouting angiogenesisIrene Aspalter The Francis Crick Institute UK15 15 15 30Engineering extracellular vesicles to permeabilize the blood brain barrierFrancesca Tomatis University of Coimbra Portugal15 30 16 00A molecular atlas of brain vascular interactions reveals a spatiotemporal requirement of TGF signaling in brain vascularizationAlexandre Dubrac University of Montreal Canada16 00 16 30Coffee break meet the speakers16 30 16 45Mechanosensory regulation of intestinal regeneration in Drosophila through the vascular stem cell nicheJessica Perochon University of Glasgow UK16 45 17 00The YAP TAZ Notch crosstalk determines angiogenesis mechanoregulation and its spatiotemporal control in silicoTomasso Ristori Eindhoven University of Technology The Netherlands17 00 17 30Engineering tissue specific human vascular network for organ repair and tumor targetingShahin Rafii Weill Cornell USA17 30 18 00Flash talks 48 Marta Cherubini 68 Urszula Kalucka 100 Sara Silva Pereira 106 Theano Tsikari 110 Pilar Villacampa18 00 20 00Poster session 2 even numbers See the poster listing here 20 00 22 00Conference dinner Day 3 Wednesday 8 May 2024 Time Europe Barcelona Speaker09 00 10 00Keynote lecture Engineering vascularized tissue flapsShulamit Levenberg Technion Israel Institute of Technology IsraelSession 6 LymphaticsChair Maike Frye10 00 10 30Applying the finishing touch VEGF C processing is a critical process for lymphangiogenesisStefan Schulte Merker WWU M nster GermanyNot available on demand10 30 11 00Coffee break Meet the speakers 11 00 11 30Direct specification of lymphatic endothelium from mesenchymal progenitorsOliver Stone University of Oxford UK11 30 11 45Biomaterial driven three dimensional lymphangiogenesis model using click gelatin hydrogelsDana E Al Ansari Imperial College London UKNot available on demand11 45 12 15Mechanisms of lymphatic vessel renewal and specializationTatiana Petrova University of Lausanne SwitzerlandNot available on demand12 15 13 45LunchSession 7 Vascular cardiobiology and engineeringChairs Kristina Haase and Milica Radisic13 45 14 15Tissue specific in vitro vascular models to study development and diseaseKristina Haase EMBL Barcelona SpainNot available on demand14 15 14 30Magnetically assembled arrays of microvascular networks on chipKatarzyna Rojek Polish Academy of Sciences Poland14 30 14 45Vascular smooth muscle cell phenotypic switching revealed in CADASIL patient derived iPSC 3D Vessel on Chip modelMarc Vila Cuenca Leiden University Medical Center The Netherlands14 45 15 15Unlocking the potential of organoid and tissue models for drug discovery with engineered vasculaturesBoyang Zhang McMaster University CanadaNot available on demand15 15 15 45Microfluidic vessels on chips for disease modelingAndries van der Meer University of Twente The NetherlandsNot available on demand15 45 16 00Closing Remarks and short talk poster prize awards Practical information Registration fees and abstract submission On site registration fees include admission conference materials meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Virtual registration fees include access to all of the talks livestreamed and on demand and facility to submit questions On site Academia 425On site PhD Student 325On site Industry 750On site Journal Editors 250Virtual Academia 200Virtual PhD Student 150Virtual Industry 275 Editors from scientific journals are allowed to attend at a reduced rate but asked to contribute to the conference in return by taking part in meet the editors sessions or other planned activities within the programme A letter to support your visa application will be issued on request once payment of the registration fee is confirmed We recommend that you book your visa appointment as soon as possible to avoid any delay with your visa application Accredited journalists may be eligible to register for complimentary press registration Registrants may be required to provide accreditation or equivalent proof of press membership after registration Please contact Aline Schnieder for more information Please note that we do not offer complimentary registrations for editors of scientific journals Confirmation and payment Registration will be on a first come first served basis Your place can only be confirmed after payment of the registration fee If you are added to our waiting list please consider taking advantage of our offerings to participate virtually On site participants Types of payments accepted are international bank transfers and credit card payments Virtual participants We are only able to accept card payments In exceptional cases we can accept bank transfers Please contact events embl de for details Abstract submission Only participants registering to attend the on site event are eligible to submit an abstract Abstracts will not be accepted from virtual participants After registration you can submit your abstract via a separate link that will be provided in the email confirmation Alternatively you can access the link on the confirmation page directly after registering The same login credentials are used for both processes Please note Abstract body The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised Title The title should not exceed 20 words Only the first word of the title should start with a capital letter and the rest should be lowercase Authors and affiliations Please fill in the author s details as requested in the online form The compulsory fields are First Name Last Name Organisation Name Affiliation or Company Country and Email Kindly mark only one author in the role of First Author and please don t forget to indicate who will be the Presenter Please enter your co authors correctly via the system by adding accounts together with their organisation institute Do not copy paste them into the body of the abstract text as they will not be indexed in the abstract book Presentation types When submitting your abstract you can apply for an oral or poster presentation A selection process will take place with the results announced 2 3 weeks after the abstract submission deadline For detailed instructions on how to submit a conference abstract follow the instructions provided in this video Please check our FAQs pages for further information on how to submit an abstract Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of registration fee waivers travel grants and childcare grants Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course or conference Travel grant The travel grant will cover the cost of travel to an on site event airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from within Europe up to 1000 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from outside Europe up to 500 for any participant travelling to an EMBO Workshop up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Workshop up to 700 for any participant working in Croatia Czech Republic Estonia Greece Hungary Italy Lithuania Luxembourg Poland Slovenia and Turkey travelling to an EMBO Workshop Registration fees are only covered for EMBO Workshops The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant There is the possibility to apply for a childcare grant to offset child care costs incurred by participants speakers and organisers when attending a conference Eligible costs include but are not limited to fees for a baby sitter or child care facility and travel costs for a caregiver Please note that priority will be given to early stage researchers In order to apply for this grant you must be registered by the abstract submission deadline There is a limited amount of funding available for the childcare grants and funds will be distributed amongst eligible applicants Application On site participants You may apply for financial assistance when submitting your abstract In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Virtual participants If you are attending virtually you can apply for financial assistance in the submission portal by the abstract deadline Read the instructions on how to apply for financial assistance Only submissions for financial assistance will be accepted Presentation abstracts cannot be submitted here and will be declined In your application you will be asked to summarise your current work answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Selection The scientific organisers will select the recipients of registration fee waivers and travel grants during the motivation letter or abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection for registration fee waivers and travel grants is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Childcare grants will be allocated in the same timeframe 6 8 weeks before the event start date Please note that priority will be given to early stage researchers Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details View our list of external funding opportunities and information on attending a conference as an event reporter For further information about financial assistance please refer to the FAQ page Venue EMBL Barcelona is located at the Barcelona Biomedical Research Park PRBB The PRBB is located on Barceloneta seafront between Hospital del Mar and the Arts Hotel in the Olympic Port of Barcelona Address Barcelona Biomedical Research Park C Doctor Aiguader 88 08003 Barcelona The conference is taking place in the PRBB auditorium It is located on a raised level in the heart of the PRBB building overlooking the sea with independent access from the rest of the building Access to the Auditorium will be by the stairs located at the entrance of the inner square of the building For people with limited mobility the access through lifts up the 1st floor can be used While on campus please wear your conference badge at all times for security purposes PRBB EMBL Barcelona PhotoCredit Jordi Casa as EMBL Accommodation Accommodation is not included in the conference registration fee Below is a list of hotels that are located near the conference venue Please get in touch with them directly for availability and prices Please note that a city tax per person per night for the stay needs to be paid whether you book in a hotel or through Airbnb Hotel nameAddressBookingsH10 MarinaAvinguda del Bogatell 64 68 Olympic Village 08005 Barcelona map website Tel 34 933 09 79 17 reservas hmb h10hotels com H10 Port VellPas de Sota Muralla 9 08003 Barcelona map website Tel 34 933 10 30 65 reservas hpv h10hotels comH10 MontcadaVia Laietana 24 Ciutat Vella 08003 Barcelona map website Tel 34 932 68 85 70 reservas hm h10hotels comH10 UniversitatRonda de la Univ 21 L Eixample 08007 Barcelona map website Tel 34 933 42 78 50 reservas hu h10hotels comH10 UrquinaonaPl d Urquinaona 2 L Eixample 08010 Barcelona map website Tel 34 932 38 20 40 reservas2 hup h10hotels comHotel SB IcariaAv d Ic ria 195 08005 Barcelona map website Tel 34 932 21 82 00 reservations icaria sbhotels esHotel Ibis StylesCarrer de Llull 71 08005 Hb004742 Barcelona map website Tel 34 934 83 37 48 H9663 accor comMotel OnePg de Pujades 11 13 Sant Mart 08018 Barcelona map website Tel 34 936 26 19 00 iforteza motel one comDerby HotelsHotel Claris map website Hotel Granados map website Hotel Balmes map website Hotel Astoria map website Suites Avenue map website Tel 34 934 876 262 recepcionclaris derbyhotels com Tel 34 934 929 670 granados83 derbyhotels com Tel 34 934 511 914 balmes derbyhotels com Tel 34 932 098 311 astoria derbyhotels com Tel 34 934 874 159 recepsuitesavenue derbyhotels comRESA campus del Mar ResidenciaPg Salvat Papasseit 4 08003 Barcelona map website Tel 34 933 90 40 00 campusdelmar resa esRESA La Ciutadella ResidenciaPasseig Pujades 33 37 08018 Barcelona map website Tel 34 933 94 32 00 ciutadella resa es On site information Catering Lunches and coffee breaks are included in the registration fee The lunch buffets and coffee breaks will be set up in front of the Auditorium Snacks will be served on the first evening of the workshop during the Welcome reception PRBB terrace as well as during the poster sessions groundfloor beneath the Auditorium Dinners are at the participants own expense unless otherwise specified Please wear your badge at all times when serving yourself No food or drinks are allowed in the PRBB auditorium Electricity and charging station The mains voltage in Barcelona is 230 volts AC The flat European standard and the Schuko plug CEE 7 7 fit into the Spanish sockets Most Europeans do not need to buy an adapter plug for Spain Please note that there are no power outlets in the auditorium You can recharge your electronic devices at the reception area We kindly ask you to bring your own charger cables The charging station will be left unattended Health and safety notes Please read EMBL Barcelona s COVID 19 terms and conditions for events Smoking is prohibited in all PRBB facilities Eating and drinking is prohibited in the Auditorium Do not enter any restricted areas or the laboratories unless authorised to do so Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required Assist the casualty and provide first aid if trained to do so Take to Hospital del Mar Pg Maritim Barceloneta 23 31 OR Dial the emergency number 1020 from any internal phone OR Dial 112 Please report all accidents to the Conference Officer at the Registration Desk In case of fire Press the nearest fire alarm button or dial the emergency number 1020 from any internal phone There will be a loudspeaker announcement in Catalan Spanish English if an evacuation is required On hearing the evacuation message leave the building promptly following the escape route and exit signs and proceed to the meeting point Punto the reunion on Passeig Maritim Barceloneta next to the sea side Beyond first aid Please remember to bring your own medication if needed to the conference Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor Internet It is easy to access the internet via a wireless connection in any area of the building When connecting a mobile device the operating system automatically recognises the network PRBB The password for this network is darwin1809 The PRBB also participates in the Eduroam project which aims to allow network access for visitors from academic institutions associated with Eduroam Access to the service is always delivered with the same credentials as in the home institution Lost and found Lost and Found items are kept at Registration and will be stored at the EMBL Barcelona reception for a short whileafter the EMBO workshop Luggage There are no lockers available on site to store your belongings It is highly recommended to leave any valuables in your accommodation An unguarded wardrobe area is behind the registration desk You may use this wardrobe at the last day of the Workshop to store your luggage The venue is directly located at the beachside Be aware of your surroundings and belongings when leaving the building Phone numbers In case of emergency contact Security on the ground floor Ext 1020 0034933160020 Reception Ext 1000 or 0034933160000 Below are the most important emergency service phone numbers for Barcelona Fire service 080 Medical emergencies 061 Police Mossos d Esquadra 088 The Mossos d Esquadra are Catalonia s autonomous community police force They are responsible for crime investigations crime prevention and assistance at accident scenes Gu rdia Urbana 092 The Gu rdia Urbana are responsible for public order by patrollling the roads and streets They also look after traffic safety and control The Guardia Urbana are also the first point of call for everyday situations such as neighbourhood disputes like noise etc All general emergencies 112 If you become ill during the event please notify the Conference Officer s immediately Photography During the conference an EMBL Photographer may be taking photographs If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Pickpockets It is highly recommended to leave any valuables in your accommodation The venue is located at the beachside which is a very busy area Be aware of your surroundings and belongings when leaving the building Sightseeing A variety of activities in Barcelona can be found in this website https www barcelona tourist guide com Time Spain operates on Central European time CET which means that the country is 6 hours ahead of eastern standard time EST in the United States and 1 hour ahead of Greenwich mean time GMT Travel to and from the venue Our EMBO Workshop partner hotel the H10 Marina is a 15 minutes walk to the venue If you prefer you can also take the bus The next bus stop is in 6 minutes walking distance to the hotel Line V27 is departing from Av Ic ria Joan Mir to Pg Mar tim Hospital del Mar From there it is another 3 minute walk Additionally a taxi stand is located just outside the hotel main entrance Hotel address Avinguda del Bogatell 64 68 Olympic Village 08005 Barcelona Useful Spanish expressions EnglishSpanishHelloHolaGood morning Good afternoon Good evening Good nightBuenos d as Buenas tardes Buenas noches Buenas nochesI m sorryLo siento PerdonaExcuse me Perd neme How are you C mo est s I m fine thanks And you Estoy bien gracias Y usted What is your name C mo te llamas My name isMe llamoDo you speak English Habla usted Ingl s I don t understandNo entiendoPlease speak more slowlyPor favor hable m s despacioThank youGraciasWhere is the toilet D nde est el servicio Please call me a taxiPuedes avisar llamar un taxi por favor How do I get to Como llego a A beer two beers please Una cerveza dos cervezas por favor A glass of red white wine pleaseUn vaso de vino tinto blanco por favor The menu please El men por favor Is there a local speciality Hay alguna especialidad local I m VegetarianSoy vegetariano aIt was deliciousEstaba deliciosoThe bill pleaseLa cuenta por favorI have a headacheMe duele la cabezaI have a sore throatTengo dolor de gargantaMy stomach hurtsMe duele el est magoI m allergic toSoy al rgico aI need a doctor who speaks EnglishNecesito un m dico que hable ingl s Transport information Getting to Barcelona By Plane Barcelona El Prat airport is located in El Prat de Llobregat just 12 km South West of the Barcelona city centre It has two passenger terminals Terminal 1 T1 and Terminal 2 T2 The airport has allocated airlines to terminals regardless of the destination of the flight Airport Transfers to the city centre The Aerob s is an express bus service that connects the Barcelona El Prat airport with the city centre Pla a Catalunya in 35 minutes You can take the Aerob s outside Terminal 1 A1 and Terminal 2 A2 This service runs every day of the year with departures between 5 and 15 minutes From the city centre you can take the metro or a bus to move around Barcelona The train service R2 line runs approximately every 30 minutes to and from Barcelona airport to the city centre The journey takes 25 minutes The train service operates from Terminal 2 T2 To get from T2 to T1 use the shuttle bus service Bus transit T1 T2 If you travel from the airport to the city centre you can get off at Barcelona Sants Passeig de Gr cia or Clot which are serviced by metro stops You can also take the metro line L9 orange from the airport It departs at Terminal 1 and connects at stations Torrassa L1 and L10 Sud Collblanc L5 and L10 Sud with metros to the city centre You will find a taxi rank outside any of the main terminal exits Look for the sign pointing to the nearest taxi rank All official Barcelona taxis are black and yellow and are required to charge you only the value on the taximeter plus any surcharge e g luggage or night The rates and surcharges are displayed inside the cab In Barcelona a taxi may be either ordered by phone found at authorised taxi rank or flagged down in the street Getting to Barcelona By train Barcelona Sants is the main train station for national and international arrivals and departures in Barcelona It is situated in pla a dels Pa sos Catalanes Barcelona National and regional trains also depart from Fran a station It is located at avinguda Marqu s de l Argentera s n Barcelona Spanish Railways RENFE Public Transport in Barcelona Metro and tram The metro network of Barcelona is very good and the trains are frequent and quick You do not have to worry about timetables Almost all attractions are within walking distance of a metro or tram station When there are no subways the gap can be filled by tram You can find the operating hours of the metro and tram here Buses The operating times of the buses are different for each line You will find a notice board with the timetable at each stop They operate from about 5 00 clock to about 22 00 clock Night bus NitBus Both the metro and the buses do not run all night In Barcelona there is a fairly dense network of night buses to get you back to your hotel all night long Except for the line N0 all lines stop at Pla a Catalunya and can change there The N0 line is a circular line that allows you to circle around the city center and change to the other NitBus The night buses are operated by the private operator AMB which is why the Barcelona Card and Hola BCN Ticket are not valid The N17 line goes to the airport The operating hours of the NitBus are different for each line but they run from about 22 00 to 05 00 clock Sponsors Bronze sponsor Media partners EMBO Journal an EMBO Press Journal International Union of Biochemistry and Molecular Biology Medinformatics a Bon View Publishing journal Open Biology a Royal Society journal Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information on sponsoring possibilities If you are interested in becoming a media partner of this event please visit our media partnerships webpage Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsoring embl de Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9 Leaderboard 728 90...

Maria Bernabeu, Claudio Franco, Stephan Huveneers, Milica Radisic

EMBO Workshop

EMBL Barcelona

1 May 2024

Harmony in diversity: exploring the rich microbiomes of South American wildlife

Edit

May 01, 2024 15:302024WebinarVirtual

Description Colombia and northern South America is known as a biodiversity hotspot but at the basis of that diversity is the microbial communities With recent advances in metagenomics the microbial communities and genomic composition has started to be characterised by unveiling a whole new world that is highly interconnected with macro organisms and the environment This webinar will illustrate the intricate world of microbial communities associated with diverse South American fauna From the high altitude realms of neotropical bumblebees to the depths of coral reefs we ll journey through the microbiome landscapes of beings like spectacled bears woolly monkeys lichens shrimps among others Discover the unseen connections shaping the health and resilience of these unique ecosystems You may either watch the entire presentation from the introduction or navigate directly to a specific section by clicking the links provided below IntroductionExploring microbial diversity in pacific coralsHow do probiotic species protect shrimp from disease The gut microbiota in Andean bearsMicrobiota diversity is related to dietary diversityMicrobial diversity during the fermentation of cacaoQ A...

Virtual

24 April 2024

Introduction to the Ensembl Bacteria genome browser

Edit

April 24, 2024 15:302024WebinarVirtual

Description Ensembl Bacteria is a browser for bacterial and archaeal genomes In this webinar we will explore Ensembl Bacteria to learn more about the latest data and where it came from view annotation of molecular interactions involving bacterial genes and comparative genomics data involving key bacterial species You may either watch the entire presentation from the introduction or navigate directly to a specific section by clicking the links provided below IntroductionWhy do we need genome browsers Ensembl Bacteria featuresTools in Ensembl BacteriaFinding a bacterial speciesHelp and documentation...

Virtual

23 April - 26 April 2024

Organismal physiology

Edit

April 23, 2024 00:002024ConferenceEMBL Heidelberg, Virtual

Description OverviewSpeakersPreliminary programmePractical informationSponsorsAbout Overview We regret to inform you that this event has been cancelled Please have a look at our other upcoming events here Symposium overview Like a machine any organism even the simplest is a functional unit coherent and integrated We are far from having elucidated in complex organisms the entire structure of these functional units A major outcome of research using model organisms has been to address this central question of biology that was stated so clearly and candidly by J Monod in 1969 Genetic studies in model organism have first revealed that we are far from knowing all the functions fulfilled by various organs in vertebrates or invertebrates In doing so this body of work has nonetheless led to unprecedented progress in our understanding of how homeostasis of an entire organism is maintained As a result modern physiology has slowly moved from a purely molecular discipline back to rediscovering its holistic nature The powerful combination of molecular and physiological approaches is revealing new insights into energy metabolism endocrinology cardiovascular and renal physiology as well as the regulation of cognitive and immune functions Symbiotic interactions with resident microbes have added a further dimension to the study of host physiology This symposium aims to provide a high visibility platform to scientists from multiple disciplines who use molecular genetic tools to probe inter organ communication signals that maintain homeostasis By bringing together scientists interested in various aspects of vertebrate and invertebrate animal physiology we will foster interactions between them that will accelerate the discovery of novel physiologies This meeting will also directly address a fundamental and long term goal of the study of physiology how can recent developments in whole organism physiology pave the way to novel adapted and efficient therapies for multiple degenerative diseases Picking up from where the virtual 2022 EMBO EMBL Symposium Inter organ communication in physiology and disease left off the 2024 event will bring together a new generation of scientists face to face to contribute critically to engaging in this emerging cross disciplinary field Session topics Physiology of behaviour Physiology of metabolism Neuroimmune interactions Physiological transitions and reproduction Organismal immunology Physiology of the gut and its microbes What past participants say about the Symposium Emerging important topic excellent science unpublished work discussed What you look for in conferences Let s meet for real next time Fran ois Leulier ENS de Lyon France I was very happy to be part of this first conference on inter organ communication I learned many new things Ionel Sandovici University of Cambridge UK Speakers Speakers Yasmine Belkaid National Institutes of Health NIH USA Esther Borges Florsheim Arizona State University USA Jens Br ning Max Planck Institute for Metabolism Research Germany Miguel Const ncia University of Cambridge UK Julia Cordero University of Glasgow UK Sidonia Fagarasan RIKEN Center for Integrative Medical Sciences Japan Ilana Gabanyi Instituto Gulbenkian de Ci ncia Portugal Anoj Ilanges Howard Hughes Medical Institute USA Yoav Livneh Weizmann Institute of Science Israel Lolitika Mandal Indian Institute of Science Education and Research Mohali India Elvira Mass Limes Institute Bonn Germany Ryusuke Niwa University of Tsukuba Japan Christoph Thaiss University of Pennsylvania USA David Tingley Harvard Medical School USA Sophie Ugolini Centre d immunologie de Marseille Luminy France Claire Wyart Paris Brain Institute France Scientific Organisers Gerard Karsenty Columbia University USA Irene Miguel Aliaga MRC London Institute of Medical Sciences and Imperial College London UK Asya Rolls Technion Israel Institute of Technology Israel Miguel Soares Instituto Gulbenkian de Ci ncia Portugal Conference organisers Luana Ribeiro EMBL Heidelberg Germany Preliminary programme Are you on social media Post using EMBLPhysio and don t forget to tag EMBLEvents Please note that the programme is subject to change Some speakers may need to join virtually to give their talk For registered participants recorded talks will be accessible on demand for 2 weeks after the end of the event unless indicated otherwise Day 1 Tuesday 23 April 2024 Time Europe Berlin Speaker12 30 14 00Registration and light refreshments14 00 14 15Opening remarks14 15 18 00Session 1 Physiology of metabolism14 15 14 45Hypothalamus dependent control of liver metabolismJens Bruning Max Planck Institute for Metabolism Research Germany14 45 15 00Selected short talk 115 00 15 15Selected short talk 215 15 16 00Coffee Break and Meet the speakers16 00 16 30A single cell homeostat for cellular excitabilityDavid Tingley Harvard Medical School USA16 30 16 45Selected short talk 316 45 17 00Selected short talk 417 00 18 00Poster sneak peek18 00 19 30Dinner in Canteen 19 30 21 00Pub Quiz in Canteen21 00 22 00After dinner drinks in the RTL Day 2 Wednesday 24 April 2024 Time Europe Berlin Speaker09 00 12 00Session 2 Physiology of behaviour09 00 09 30Talk title TBCAnoj Ilanges Howard Hughes Medical Institute USA09 30 09 45Selected short talk 509 45 10 00Selected short talk 610 00 10 30Coffee Break and Meet the speakers10 30 11 00Talk title TBCYoav Livneh Weizmann Institute of Science Israel11 00 11 15Selected short talk 711 15 11 45Talk title TBCClaire Wyart Paris Brain Institute France11 45 12 00Selected short talk 812 00 13 30Lunch 13 30 16 30Session 3 Physiological transitions and reproduction13 30 14 00Talk title TBCMiguel Constancia Wellcome MRC Institute of Metabolic Science University of Cambridge UK14 00 14 15Selected short talk 914 15 14 30Selected short talk 1014 30 15 00Coffee Break and Meet the speakers15 00 15 30Developmental Programming of Tissue Resident MacrophagesCElvira Mass Limes Institute Germany15 30 15 45Selected short talk 1115 45 16 00Selected short talk 1216 00 16 30Flash talks16 30 18 00Poster Session 1 odd numbers 18 00Free evening Day 3 Thursday 25 April 2024 Time Europe Berlin Speaker09 00 12 00Session 4 Neuroimmune interactions09 00 09 30Body brain communication in health and diseaseChristoph Thaiss University of Pennsylvania USA09 30 09 45Selected short talk 1309 45 10 00Selected short talk 1410 00 10 30Coffee Break and Meet the speakers10 30 11 00Talk title TBCSophie Ugolini Centre d immunologie de Marseille Luminy France11 00 11 15Selected short talk 1511 15 11 45Talk title TBCEsther Borges Florsheim Arizona State University USA11 45 12 00Selected short talk 1612 00 13 30Lunch 13 30 16 30Session 5 Organismal immunology13 30 14 00Talk title TBCLolitika Mandal Indian Institute of Science Education and Research India14 00 14 15Selected short talk 1714 15 14 30Selected short talk 1814 30 15 00Coffee Break and Meet the speakers15 00 15 30Neuronal sensing of bacterial compounds and their downstream effects on metabolismIlana Gabanyi Instituto Gulbenkian de Ci ncia Portugal15 30 15 45Selected short talk 1915 45 16 15Talk title TBCSidonia Fagarasan RIKEN Center for Integrative Medical Sciences Japan16 15 16 30Selected short talk 2016 30 17 00Flash talks17 00 18 30Poster Session 2 even numbers 18 30 20 30Conference Dinner 20 30 00 00Conference Party Day 4 Friday 26 April 2024 Time Europe Berlin Speaker09 00 12 00Session 6 Physiology of the gut and its microbes09 00 09 30Talk title TBCYasmine Belkaid Institut Pasteur France09 30 09 45Selected short talk 2109 45 10 15Talk title TBCJulia Cordero University of Glasgow UK10 15 10 45Coffee Break and Meet the speakers10 45 11 00Selected short talk 2211 00 11 30Talk title TBCRyusuke Niwa University of Tsukuba Japan11 30 11 45Selected short talk 2311 45 12 00Closing Remarks and Poster Prize Announcements12 00Packed Lunch and departure Practical information Registration fees and abstract submission On site registration fees include admission conference materials meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Virtual registration fees include access to all of the talks livestreamed and on demand and facility to submit questions On site Academia 725On site PhD Student 625On site Industry 925On site Journal Editors 300Virtual Academia 225Virtual PhD Student 175Virtual Industry 275 Editors from scientific journals are allowed to attend at a reduced rate but asked to contribute to the conference in return by taking part in meet the editors sessions or other planned activities within the programme A letter to support your visa application will be issued on request once payment of the registration fee is confirmed We recommend that you book your visa appointment as soon as possible to avoid any delay with your visa application Accredited journalists may be eligible to register for complimentary press registration Registrants may be required to provide accreditation or equivalent proof of press membership after registration Please contact Luana Ribeiro for more information Please note that we do not offer complimentary registrations for editors of scientific journals Confirmation and payment Registration will be on a first come first served basis Your place can only be confirmed after payment of the registration fee If you are added to our waiting list please consider taking advantage of our offerings to participate virtually On site participants Types of payments accepted are international bank transfers and credit card payments Virtual participants We are only able to accept card payments In exceptional cases we can accept bank transfers Please contact events embl de for details Abstract submission Only participants registering to attend the on site event are eligible to submit an abstract Abstracts will not be accepted from virtual participants After registration you can submit your abstract via a separate link that will be provided in the email confirmation Alternatively you can access the link on the confirmation page directly after registering The same login credentials are used for both processes Please note Abstract body The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised Title The title should not exceed 20 words Only the first word of the title should start with a capital letter and the rest should be lowercase Authors and affiliations Please fill in the author s details as requested in the online form The compulsory fields are First Name Last Name Organisation Name Affiliation or Company Country and Email Kindly mark only one author in the role of First Author and please don t forget to indicate who will be the Presenter Please enter your co authors correctly via the system by adding accounts together with their organisation institute Do not copy paste them into the body of the abstract text as they will not be indexed in the abstract book Presentation types When submitting your abstract you can apply for an oral or poster presentation A selection process will take place with the results announced 2 3 weeks after the abstract submission deadline For detailed instructions on how to submit a conference abstract follow the instructions provided in this video Please check our FAQs pages for further information on how to submit an abstract Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of both registration fee waivers and travel grants These are available for on site participants at EMBL Conferences and EMBO EMBL Symposia and for on site and virtual participants at EMBO Workshops We are currently working on securing funding for all virtual participants and ask that you please apply for financial assistance for both on site and virtual participation Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course or conference Travel grant The travel grant will cover the cost of travel to an on site event airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from within Europe up to 1000 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from outside Europe up to 500 for any participant travelling to an EMBO Workshop up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Workshop up to 700 for any participant working in Croatia Czech Republic Estonia Greece Hungary Italy Lithuania Luxembourg Poland Slovenia and Turkey travelling to an EMBO Workshop Registration fees are only covered for EMBO Workshops The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant EMBO Workshops only For EMBO Workshop participants with children there is the possibility to apply for a childcare grant to offset child care costs incurred by participants or speakers when participating at a conference Eligible costs include fees for a baby sitter or child care facility travel costs for a caregiver or travel costs for taking the child to the meeting etc Please note that priority will be given to early stage researchers A maximum amount of 500 can be awarded per participant applying for an EMBO childcare grant In order to apply for this grant for EMBO Workshops you must be registered by the abstract submission deadline Application On site participants You may apply for financial assistance when submitting your abstract In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Virtual participants If you are attending virtually you can apply for financial assistance in the submission portal by the abstract deadline Read the instructions on how to apply for financial assistance Only submissions for financial assistance will be accepted Presentation abstracts cannot be submitted here and will be declined In your application you will be asked to summarise your current work answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Selection The scientific organisers will select the recipients of all financial assistance during the abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details View our list of external funding opportunities and information on attending a conference as an event reporter For further information about financial assistance please refer to the FAQ page Accommodation and shuttles Accommodation is not included in the conference registration fee The hotels below have rooms on hold for participants until Monday 25 March 2024 in some cases at special rates Please email the hotel directly quoting the booking code EES24 05 to confirm the exact price of the room Hotel AnlageHotel ibis HeidelbergPremier Inn Heidelberg CityHotel Bayrischer Hof ISG Hotel Staycity Aparthotel HeidelbergB B HotelLeonardo Hotel Heidelberg City CentreSteffi s Hostel HeidelbergExzellenz HotelMeininger HeidelbergHotel Vier Jahreszeiten HeidelbergHotel Holl nder Hof Hotel MonptiHilton Heidelberg Conference shuttle buses Conference shuttle buses are free of charge for participants and depart from designated bus stops near the hotels to EMBL and back mornings and evenings The bus stops for this conference are Staycity Aparthotel Speyerer Str 7 Kurf rsten Anlage Opposite Main Train Station Premier Inn Kurf rsten Anlage 23 Leonardo Hotel Heidelberg City Center Bergheimer Str 63 Neckarm nzplatz Heidelberg Tourist Information Peterskirche Bus stop ISG Hotel Im Eichwald 19 View Conference shuttle bus stops and hotels in a larger map Please note that not every bus stop will be used for every event Further details Address EMBL Meyerhofstra e 1 69117 Heidelberg Germany For further information on getting to EMBL Heidelberg visit Public Transportation to the Venue For information about accommodation and local transportation please refer to the FAQ page On site information Catering All meals and coffee breaks are included in the registration fee Our catering staff will prepare a wide variety of vegetarian meals meat and fish dishes soups pasta fresh fruit and vegetables as well as a variety of desserts Please wear your badge at all times when serving yourself No food or drinks are allowed in the auditorium Charging lockers There are lockers available next to the stairs leading down into the Auditorium You will find some of those equipped with sockets to charge your smartphone tablet etc Electricity and charging station In most places the electricity is 220 volts AC 50 cycles An adaptor and a plug that fits the German socket may be needed for your appliances laptop i e American Japanese etc A USB charging station for electronic devices is available at the registration desk EMBL merchandise If you are interested in purchasing an EMBL souvenir products presented in the glass display in the registration area please ask at the registration desk for more information Health and safety notes Please read EMBL s COVID 19 safety policy for on site events Do not smoke in any EMBL building Eating and drinking is prohibited in the Auditorium and all laboratories Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required The first aid room is located next to the ATC Registration Desk room 10 205 Dial the Emergency number 222 from any EMBL internal phone only Where is the accident What happened How many injured Emergency number 06221 387 7821 from mobile phones Please report all accidents to the conference officer at the registration desk In case of fire Press the nearest fire alarm button or the Emergency number 222 from any internal phone A loud fire alarm will go off if an evacuation is required On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting points Do not use the lifts Beyond first aid Please remember to bring your own medication if needed to the conference Note that the next pharmacy is a 4 minute drive from the EMBL but for many medications you will be required to see a doctor to get a prescription Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg In any case the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary Internet Wi Fi is available on campus using the EMBL Events network and the event specific password which will be provided on site The eduroam network secure worldwide roaming access service developed for the international research and education community is also available Lost and found Lost and Found items are kept at the registration desk until the end of the conference Luggage There are lockers available on site to store your luggage which require a 2 EURO coin to operate There is another luggage room on level E0 which is free to use but remains unlocked during the conference Nursing room There is a nursing room available in the ATC Rooftop Lounge on level A29 Photography During the conference an EMBL Photographer may be taking photos If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Printing We can help to print your boarding pass train ticket Please send it to events embl de and collect your print outs at the registration desk Room for prayer yoga and meditation There is a room for prayer meditation and yoga located on level E0 behind the Auditorium Please be respectful of others using the room Sightseeing A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing Travel to and from the venue During the event we provide conference shuttle buses to and from EMBL In addition there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time Information on the conference shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page Useful German expressions HelloHalloGoodbyeAuf Wiedersehen formal Tsch ss informal Good morningGuten MorgenGood afternoonGuten TagGood eveningGuten AbendGood nightGute NachtI m sorryEs tut mir leidExcuse me Entschuldigen SieHow are you Wie gehts I m fine thanks And you Mir geht es gut danke Und Dir Ihnen What is your nameWie hei en Sie formal Wie hei t Du informal My name isIch hei e Do you speak EnglishSprechen Sie englisch I don t understandIch verstehe nichtPlease speak more slowlyK nnen Sie bitte langsamer sprechenThank youDankesch nWhere is the toilet Wo ist die Toilette Please call me a taxiBitte rufen Sie mir ein TaxiHow do I get to Wie komme ich zum zur A beer two beers pleaseEin Bier zwei Bier bitteA glass of red white wine pleaseEin Glas Rot Weisswein bitteThe menu pleaseDie Speisekarte bitteIs there a local speciality Gibt es eine Spezialit t aus dieser Gegend I m vegetarianIch bin VegetarierIt was deliciousEs war hervorragendThe bill pleaseDie Rechnung bitteI have a headacheIch habe KopfschmerzenI have a sore throatIch habe HalsschmerzenMy stomach hurtsIch habe MagenschmerzenI m allergic toIch bin allergisch gegenI need a doctor who speaks EnglishIch brauche einen Arzt der Englisch spricht Virtual participation What s included Access to all the livestreamed talks Video library of the recorded talks during and after the event Facility to submit questions Talks will only be recorded upon speaker s consent Please note that only on site participants are able to submit abstracts and participate in the poster sessions Event platform We are using an event platform for this conference More information about the platform will be shared ahead of the conference Guidelines Do not broadcast the conference to unregistered participants You are encouraged to tweet and post about the event Tweet unless the speaker specifically says otherwise but be mindful of unpublished data Please do not capture transmit or redistribute data presented at the meeting Additional information can be found in our Code of Conduct Health and well being It is important to stay healthy and move around especially when you are attending an event virtually We have put together a few coffee break stretches and yoga videos in the conference platform for you to enjoy during the event How to ask questions Please use the Q A function in the event platform If you have any other questions you can go to the Help Desk in the event platform Click on more on the top menu and click Help Desk Time zone The programme is planned based on the Europe Berlin time zone unless otherwise stated Please take your time zone into consideration when planning your attendance Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for participants page Sponsors Event supporter Media partners EMBO Reports an EMBO Press journal FEBS Letters International Union of Biochemistry and Molecular Biology Medinformatics a Bon View Publishing journal Open Biology a Royal Society journal PLOS Biology a PLOS journal Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de About EMBO EMBL Symposia promote scientific communication and collaboration in the European research area They provide scientists with a platform to discuss and exchange ideas on forward looking topics and new developments in the life sciences Topics emphasise upcoming developments and the interdisciplinary nature of related fields Jointly funded and organised by EMBO and EMBL and complementary to their respective courses workshops and conference programmes the symposia promote scientific communication and collaboration All symposia are held in the EMBL Advanced Training Centre ATC in Heidelberg Germany or virtually...

Gerard Karsenty, Irene Miguel-Aliaga, Asya Rolls, Miguel Soares

EMBO | EMBL Symposium

EMBL Heidelberg, Virtual

22 April - 26 April 2024

Fundamentals of widefield and confocal microscopy and imaging

Edit

April 22, 2024 00:002024CourseEMBL Heidelberg

Description OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview Registration is not yet open for this event If you are interested in receiving more information please register your interest Course overview Light microscopy is the most widely used form of microscopy for life science research The correct handling of the microscope and optimising image quality e g contrast resolution as well as experimental design according to different applications are crucial to obtain the best results This course will provide the participants with an overview of the basics of microscopy light and optics contrast techniques and imaging The confocal part will include multicolour 3D and time lapse imaging as well as spectral imaging introduction to photobleaching and photoactivation techniques Basic image analysis tools including measurement functions colocalisation and spectral unmixing as well as 3D 4D image processing will be covered both in theory and practice The course will combine lectures with intense daily hands on practices followed by discussions Audience This course is directed towards PhD students and faculty searching for instruction on light microscopy and basic image processing with basic level on microscopy Learning outcomes Participants will get an overview of the basics of microscopy Please see EMBL s COVID 19 safety recommendations for testing and other requirements to attend this on site course This course is organised in cooperation with Evident Olympus Speakers Speakers trainers and staff Heiko Gaethje Evident Scientific Germany Stefan Marawske Evident Scientific Germany Jens Marquardt Evident Scientific Germany Stefan Terjung EMBL Heidelberg Germany Peter Vander Evident Scientific Germany Scientific organisers Heiko Gaethje Evident Scientific Germany Stefan Marawske Evident Scientific Germany Jens Marquardt Evident Scientific Germany Stefan Terjung EMBL Heidelberg Germany Course organisers Catherine Casas Saavedra Course and Conference Officer EMBL Heidelberg Germany Irena Provaznikova Training Laboratory Manager EMBL Heidelberg Germany Programme Are you on social media Post using EMBLWidefieldConfocal and don t forget to tag EMBLEvents Day 1 Monday 22 April 2024 Time Europe Berlin SessionLocation08 40Bus from hotel to EMBL ATC EntranceB B Hotel09 00 09 15Arrival and welcome house notesCourtyard Room A B09 15 13 00Basics of optics and microscopy Theoretical basics of light and optics Types of microscope frames and types of optics Set up bright field microscopes and the appropriate optics for different needs Cleaning centering adjusting and operating a microscope Basic set up and use of imaging devicesHands on session 1Courtyard Room A B13 00 14 00LunchEMBL Canteen14 00 15 00Contrast methods Introduction into contrast methods phase contrast and differential interference contrast DIC Courtyard Room A B15 00 17 30Contrast methods set up and alignment Set up and use of contrast methods phase contrast and differential interference contrast DICHands on session 2Courtyard Room A B17 30 18 00Discussing open questionsCourtyard Room A B18 00 19 00DinnerEMBL Canteen19 00Departure to HotelATC Entrance Day 2 Tuesday 23 April 2024 Time Europe Berlin SessionLocation08 40Bus from hotel to EMBL ATC EntranceB B Hotel08 50 09 00Arrival and coffeeCourtyard Room A B09 00 12 30Basics of digital imaging Adaptation of digital cameras and theiralignment Interpretation of image content histogram and digital filter functions Improving digital image contrastCourtyard Room A B12 30 13 30LunchEMBL Canteen13 30 16 00Fluorescence microscopy I Introduction to fluorescence microscopy Setting up of microscopes and cameras for fluorescence observation The different types of illumination sources e g mercury xenon metal halide or LED Cubes filters and objectives Find the appropriate filter combination for a given fluorochrome and applicationHands on session 3Courtyard Room A B16 00 17 30Discussing open questionsCourtyard Room A B17 30 18 30Pizza dinnerATC Rooftop Lounge18 30Departure to HotelATC Entrance Day 3 Wednesday 24 April 2024 Time Europe Berlin SessionLocation08 40Bus from hotel to EMBL ATC EntranceB B Hotel08 50 09 00Arrival and coffeeCourtyard Room A B09 00 11 30Fluorescence microscopy II Auto fluorescence a source for noise Digital imaging for fluorescence microscopy Specific needs of digital cameras Digital multicolor handling Acquisition of multidimensional images 3D time Hands on session 3 continued Courtyard Room A B11 30 11 35Group picture11 35 12 30Guided tour of the EMBL Advanced light microscopy facility ALMF ALMF12 30 13 30LunchEMBL Canteen13 30 15 00Lecture Introduction to the confocal microscopeCourtyard Room A B15 00 18 00Hands on session Group work Different applications will be covered in small groups Module 1 Multicolor imagingModule 2 Photomanipulation techniques FRAP FLIP and PhotoconversionModule 3 3D image collection and enhancement zooming resolution SNR z stacks IMARIS basicModule 4 Time lapse imaging bleaching and viability Multi Area Time Lapses and StitchingMicroscopy rooms18 00 18 30EMBL Bus via ISG Hotel to downtownATC Entrance18 30 20 00Free time20 00 22 00Dinner downtownOskar Restaurant u Vinothek Day 4 Thursday 25 April 2024 Time Europe Berlin SessionLocation08 40Bus from hotel to EMBL ATC EntranceB B Hotel08 50 09 00Arrival and coffeeCourtyard Room A B09 00 10 00FRAP and Photoconversion Talk Courtyard Room A B10 00 13 00Hands on session Group work Work in ModulesMicroscopy rooms13 00 14 00LunchEMBL Canteen14 00 18 00Hands on session Group work Comparative time lapse overnight experiment on three different setupsMicroscopy rooms18 00 19 00DinnerEMBL Canteen19 00Departure to HotelATC Entrance Day 5 Friday 26 April 2024 Time Europe Berlin SessionLocation08 40Bus from hotel to EMBL ATC EntranceB B Hotel08 50 09 00Arrival and coffeeCourtyard Room A B09 00 09 30Evaluation and summaryof overnight timelapse acquisitionCourtyard Room A B09 30 12 30Hands on session Group work Work in ModulesMicroscopy rooms12 30 13 00Tips and tricks for data presentationCourtyard Room A B13 00 13 10Closing remarksCourtyard Room A B13 10 13 25Packed lunchATC Foyer13 25EMBL Bus via Hotel to main train stationATC Entrance Practical information Registration fees and motivation letter The course is limited to 12 participants For selection purposes please note that your application will not be considered without a letter of motivation Registration Registration fees include admission course materials meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Academia 525PhD Student 525Industry 1050 A letter to support your visa application will be issued on request once payment of the registration fee is confirmed We recommend that you book your visa appointment as soon as possible to avoid any delay with your visa application Confirmation and payment The registration fee should be paid only after acceptance to the course The results will be announced approximately 2 3 weeks after the application deadline Motivation letter submission After you have logged in and successfully registered you will receive an email asking you to submit your motivation letter Click on the link provided and enter your motivation letter in the text box provided Alternatively you can submit your motivation letter by clicking on the link on the confirmation page directly after registering Instructions Include your relevant skills experience and qualifications showing why you would be suitable for the course Explain why you would like to attend including what you can contribute and how you think you will benefit from the course Please note The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised For detailed instructions please watch our video on how to submit a course motivation letter Further details For further information about registration and motivation letter submission please refer to the FAQ page Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of registration fee waivers travel grants and childcare grants Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course Travel grant The travel grant will cover the cost of travel airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Course within Europe Childcare grant There is the possibility to apply for a childcare grant to offset child care costs incurred by participants speakers trainers and organisers when attending a course Eligible costs include but are not limited to fees for a babysitter or child care facility and travel costs for a caregiver Please note that priority will be given to early stage researchers There is a limited amount of funding available for the childcare grants and funds will be distributed amongst eligible applicants Application You may apply for financial assistance when submitting your motivation letter for courses In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application For the Boehringer Ingelheim Fonds Travel Grant there is a pre application question during the motivation letter submission process and if selected you will be requested to complete a standard form and documentation consisting of your travel expense estimation Selection The scientific organisers will select the recipients of registration fee waivers and travel grants during the motivation letter or abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection for registration fee waivers and travel grants is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Childcare grants will be allocated in the same timeframe 6 8 weeks before the event start date Please note that priority will be given to early stage researchers Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details See our list of external funding opportunities and for further information about financial assistance please refer to the FAQ page Accommodation and travel Travel information For travel information please see here If you are travelling to the conference within Germany then you are eligible for the Deutsche Bahn Event Ticket called the Veranstaltungsticket in German This will result in a lower ticket price if your travel distance to Heidelberg is more than 100 km You need to provide proof of your event attendance when purchasing the ticket For more information in English see here or in German see here You can book your ticket here Hotel Accommodation is not included in the registration fee Participants are expected to book and pay for their own accommodation Single rooms have been reserved for 5 nights 21 26 April at B B Hotel After the selection process selected participants should contact the hotel directly heidelberg hotelbb com to make a booking with the booking code MIC24 01 by the deadline of Monday 25 March We recommend that all course participants stay in the dedicated hotel for the course Local transport Shuttle buses will go from the ISG Hotel to EMBL and back mornings and evenings A bus schedule and location of the bus stops will be made available prior to the meeting Further details Address EMBL Heidelberg Meyerhofstra e 1 69117 Heidelberg GermanyFor more information about accommodation and travel please refer to the FAQ page On site information Catering All meals and coffee breaks are included in the registration fee Our catering staff will prepare a wide variety of vegetarian meals meat and fish dishes soups pasta fresh fruit and vegetables as well as a variety of desserts Please wear your badge at all times when serving yourself No food or drinks are allowed in the laboratories Electricity and charging station In most places the electricity is 220 volts AC 50 cycles An adaptor and a plug that fits the German socket may be needed for your appliances laptop i e American Japanese etc A USB charging station for electronic devices is available at the registration desk EMBL Merchandise If you are interested in purchasing EMBL merchandise products presented in the glass display in the registration area please email the EMBL shop to place an order or get in contact with your Course Organiser Kindly note the EMBL shop is only open upon request and all purchases must be made in cash Euros only Health and safety notes Please read EMBL s COVID 19 safety policy for on site events Do not smoke in any EMBL building Eating and drinking is prohibited in all laboratories Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required The first aid room is located next to the ATC Registration Desk room 10 205 Dial the Emergency number 222 from any EMBL internal phone only Where is the accident What happened How many injured Emergency number 06221 387 7821 from mobile phones Please report all accidents to the conference officer at the registration desk In case of fire Press the nearest fire alarm button or the Emergency number 222 from any internal phone A loud fire alarm will go off if an evacuation is required On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting points Do not use the lifts Beyond first aid Please remember to bring your own medication if needed to the conference Note that the next pharmacy is a 4 minute drive from the EMBL but for many medications you will be required to see a doctor to get a prescription Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg In any case the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary Internet Wi Fi is available on campus Log in using the EMBL Events network and the event specific password which will be provided on site The eduroam network secure worldwide roaming access service developed for the international research and education community is also available Lost and found Lost and Found items are kept at the registration desk until the end of the conference Luggage There are lockers available on site to store your luggage which require a 2 EUR coin to operate There is another luggage room on level E0 which is free to use but remains unlocked during the conference Nursing room There is a nursing room available in the ATC Rooftop Lounge on level A29 Photography During the conference an EMBL Photographer may be taking photos If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Printing We can help to print your boarding pass train ticket Please send it to events embl de and collect your print outs at the registration desk Room for prayer yoga and meditation There is a room for prayer meditation and yoga located on level E0 behind the Auditorium Please be respectful of others using the room Sightseeing A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing Travel to and from the venue During the event we provide conference shuttle buses to and from EMBL In addition there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time Information on the shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page Additional information Address EMBL Heidelberg Meyerhofstra e 1 69117 Heidelberg Germany ATC orientation map Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page Technical requirements and event software Technical requirements Below you will find the software and technical requirements for this course Participants need to bring their own laptops which will be used to remotely access EMBL virtual machines with pre installed software You will need admin rights to install the software required to access the virtual machines If you do not have admin rights please contact your technical support team in advance to make sure the software can be installed If you have a non standard HDMI port other than type A you need to bring an adaptor Keyboard and PC mouse are available for use with a standard USB port If you have a different port type such as USB C you will need to bring your own Event software The EMBL eCampus learning platform will be used to collaborate communicate and network with all of the course participants All participants will receive information on how to join shortly before the course We recommend using Chrome Safari or Mozilla Firefox browsers for eCampus Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page COVID 19 related questions COVID 19 information for on site events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Media partners Imaging and Microscopy a Wiley magazine Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other events or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9...

Heiko Gaethje, Jens Marquard

EMBL Heidelberg

22 April - 26 April 2024

Microscopy data analysis: machine learning and the BioImage Archive

Edit

April 22, 2024 00:002024CourseVirtual

Description This virtual course will show how public bioimaging data resources centred around the BioImage Archive enable and enhance machine learning based image analysis The content will explore a variety of data types including electron and light microscopy and miscellaneous or multi modal imaging data at the cell and tissue scale Participants will cover contemporary biological image analysis with an emphasis on machine learning methods as well as how to access and use images from databases Further instruction will be offered using applications such as ZeroCostDL4Mic ilastik the BioImage Model Zoo and CellProfiler Virtual course This course will be a virtual event delivered via a mixture of live streamed sessions pre recorded lectures and tutorials with live support We will be using Zoom to run the live sessions all fully password protected with automated English closed captioning and transcription with support and both scientific and social networking opportunities provided by Slack and other methods taking different time zones into account In order to make the most out of the course you should make sure to have a stable internet connection throughout the week and are available between 08 00 18 00 BST each day In the week before the course there will be a brief induction session Computational practicals will run on EMBL EBI s virtual training infrastructure meaning participants will not require access to a powerful computer or install complex software on their own machines Selected participants may be sent materials prior to the course These might include pre recorded talks and required reading or online training that will be essential to fully engage with the course...

Meredith Willmott

Virtual

17 April 2024

Statistical thinking for microbial ecology

Edit

April 17, 2024 15:302024WebinarVirtual

Description Most microbial ecologists understand the importance of rigorous statistical analysis for conducting a replicable study However formal courses in the statistical analysis of high dimensional ecological data are rare and traditional courses in applied statistics may not teach skills applicable to modern microbiome analysis This webinar will introduce foundational concepts in statistics with a focus on applying these concepts to the analysis of modern microbiome datasets To illustrate these concepts we will use the field of differential abundance as a case study We will contrast popular differential abundance parameters and estimators specifically focusing on estimating meaningful contrasts using high throughput sequencing data You may either watch the entire presentation from the introduction or navigate directly to a specific section by clicking the links provided below IntroductionThree approaches to analysing dataCase study Microbial abundance parametersRadEmu and its applicationExamples of statistical tools suitable for different parametersQ A...

Virtual

Edit

April 11, 2024 15:302024WebinarVirtual

Description UniProt is a comprehensive expert led publicly available database of protein sequence function and variation information This webinar will give a brief introduction to the UniProt website and then highlight resources which should be of interest to people beginning work on antimicrobial resistance AMR including students early stage researchers and clinicians AMR constitutes one of the world s most urgent public health problems We have been improving the annotation of various protein classes with a known role in AMR including beta lactamases efflux pumps ABC transporters and a group of proteins essential for the survival of resistant bacteria under therapeutic concentrations of antimicrobials collectively known as the secondary resistome Using these as examples we will introduce some of the UniProt resources UniProt annotations are widely disseminated to other databases including Rhea EnsemblBacteria PATRIC Bacterial Viral Bioinformatics Resource Center BioCyc EcoCyc and KEGG Please also take this opportunity to suggest additional curation targets to us to enable us to better support ongoing AMR research...

Virtual

9 April - 12 April 2024

Diversity of plants: from genomes to metabolism

Edit

April 09, 2024 00:002024ConferenceEMBL Heidelberg, Virtual

Description OverviewSpeakersProgrammePractical informationSponsorsAboutMedia kit Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Symposium overview This inaugural EMBO EMBL Symposium will showcase the future of plant biology Going beyond the limited number of wild and crop plants that have historically been focused on modern comparative approaches are revealing the mechanistic bases and evolutionary forces driving the enormous phenotypic variation among the 400 000 plant species on Earth This conference is for biologists with an interest in plant diversity at the genomic epi genetic phenotypic and metabolic level The major topical threads will be the biology of genomes evolution of metabolic pathways and evolution of environment dependent and independent phenotypes which constitute some of the most exciting areas of contemporary biology Session topics Evolution of genomes Evolution of metabolism I Evolution of metabolism II Biology of genomes Plants in their environment Evolution of phenotypes Speakers Keynote speaker Anne Osbourn John Innes Centre UK Speakers Asaph Aharoni Weizmann Institute of Science Israel John Bowman Monash University Australia Andrea Br utigam Bielefeld University Germany C Robin Buell University of Georgia USA Christine Faulkner John Innes Centre UK Xiaoqi Feng Institute of Science and Technology Austria Austria Fernando Geu Flores University of Copenhagen Denmark Tonni Grube Andersen Max Planck Institute for Plant Breeding Research Germany Sanwen Huang Chinese Academy of Tropical Agricultural Sciences and Agricultural Genomics Institute at Shenzhen Chinese Academy of Agricultural Sciences China Xiaoguang Lei Peking University China Edwige Moyroud University of Cambridge UK Leandro Quadrana IBENS Institut de Biologie de l cole Normale Sup rieure France Seung Yon Sue Rhee Michigan State University USA Virtual speaker Aleksandra Skirycz Michigan State University USA Noah Whiteman University of California Berkeley USA Scientific organisers Barbara Ann Halkier University of Copenhagen Denmark Sarah E O Connor Max Planck Institute for Chemical Ecology Germany Detlef Weigel Max Planck Institute for Biology Germany Conference organiser Nathalie Sneider EMBL Heidelberg Germany Programme Are you on social media Post using EESPlantDiversity and don t forget to tag EMBLEvents Please note that the programme is subject to change Some speakers may need to join virtually to give their talk For registered participants recorded talks will be accessible on demand for 2 weeks after the end of the event unless indicated otherwise Please find the poster listing here Day 1 Tuesday 9 April 2024 Time Europe Berlin Speaker12 00 13 30Registration and light refreshments13 30 13 45Opening remarks13 45 14 45Keynote lecture Harnessing plant metabolic diversity for food and health applicationsAnne Osbourn John Innes Centre UK 14 45 18 15Session 1 Evolution of genomesChaired by Justyna Lalak Kanczugowska Polish Academy of Sciences Poland14 45 15 15The reinvention of potatoSanwen Huang Chinese Academy of Tropical Agricultural Sciences Agricultural Genome Institute at Shenzhen Chinese Academy of Agricultural Sciences China15 15 15 30Widespread position dependent enhancers in plantsYoav Voichek Gregor Mendel Institue GMI Austria15 30 15 45Allelic variants determine plant microbe plant interactionsNiklas Schandry Ludwig Maximilians University Germany15 45 16 15Coffee Break and Meet the speakers with Anne Osbourn Sanwen Huang16 15 16 45Evolving by jumping the role of mobile DNA in the generation of adaptive variation in response to environmental challengesLeandro Quadrana IBENS Institut de Biologie de l cole Normale Sup rieure France16 45 17 00The metabolic and genomic imprints of unparalleled growthHaim Trebes Rheinland Pf lzische Technische Universit t Kaiserslautern Landau Germany Tel Aviv University Israel17 00 17 15Illuminating biology of the red algae the forgotten plant lineageMichael Borg Max Planck Institute for Biology T bingen GermanyNot available on demand17 15 18 15Poster sneak peek18 15 19 45Dinner19 45 21 30Pub Quiz in Canteen After dinner drinks in the Rooftop Lounge Day 2 Wednesday 10 April 2024 Time Europe Berlin Speaker09 00 12 00Session 2 Evolution of metabolism IChaired by Jiawen Chen KU Leuven Belgium John Innes Centre UK09 00 09 30Let s connect to nature and explore plant metabolism in a contextAsaph Aharoni Weizmann Institute of Science IsraelNot available on demand09 30 09 45Exploring elucidating and engineering complex flavonoid glycoside biosynthesisSandra Irmisch Leiden University The NetherlandsNot available on demand09 45 10 00Leveraging the benefits of genetic mapping within local populations more fully reveals the genetic basis of defensive metabolite diversityAndrew Gloss New York University USA10 00 10 30Coffee Break and Meet the speakers with Leandro Quadrana and Asaph Aharoni10 30 11 00Biosynthesis of quinolizidine alkaloids in lupinsFernando Geu Flores University of Copenhagen Denmark11 00 11 15A novel single cell metabolomics method for the study of plant natural products biosynthesisLorenzo Caputi Max Planck Institute for Chemical Ecology Germany11 15 11 45Translational plant natural product researchXiaoguang Lei Peking University ChinaNot available on demand11 45 12 00Esculetin is biosynthesized via novel O demethylation activity in Arabidopsis thalianaAlicja Dobek University of Gdansk Poland12 00 13 30Vegetarian lunch Meet the Editors13 30 16 30Session 3 Evolution of metabolism IIChaired by Sarah E O Connor Max Planck Institute for Chemical Ecology Germany13 30 14 00Identification and functional characterization of protein metabolite interactionsAleskandra Skirycz Michigan State University USA14 00 14 15Real time evolution of plant chemical defenses in natural communitiesShuqing Xu University of Mainz Germany14 15 14 30A bipartite biosynthetic gene cluster and convergent enzyme evolution in mint monoterpenoid metabolismBenjamin Lichman University of York UK14 30 15 00Coffee Break and Meet the speakers with Fernando Geu Flores Xiaoguang Lei Aleskandra Skirycz15 00 15 30Understanding plant resilience against climate change through the lens of a thermophilic plantSeung Yon Sue Rhee Michigan State University USA Remote talk Not available on demand15 30 15 45Convergent evolution of ipecac alkaloid biosynthesisMaite Colinas Max Planck Institute for Chemical Ecology Germany15 45 16 00Plant metabolic plasticity in response to various microbesJo lle Schl pfer Sasse Universit t Z rich Switzerland16 00 16 30Flash talks odd numbers 41 Himani Agrawal 47 Jiawen Chen 59 Justyna Lalak Kanczugowska 61 Ruoxi Lin 65 Nadja Nolte 69 Izabela Perkowska 71 Claude Becker 73 Vojtech Schmidt16 30 18 00Poster Session 1 odd numbers with beer and snacks18 00Free evening Day 3 Thursday 11 April 2024 TimeEurope BerlinSpeaker09 00 12 00Session 4 Biology of genomesChaired by Douglas Domingues University of S o Paulo Brazil09 00 09 30Epigenetic reprogramming in plant germlinesXiaoqi Feng Institute of Science and Technology Austria Austria09 30 09 45Glycosylation of the transcription factor WOX4 regulates radial growth and gene expression in ArabidopsisPascal Hunziker Centre of Organismal Studies COS Heidelberg University Germany09 45 10 00Changing the structure of plant genomes by CRISPR Cas mediated chromosome engineeringMichelle R nspies Karlsruhe Institute of Technology KIT Germany10 00 10 30Coffee Break and Meet the speakers with Xiaoqi Feng10 30 11 00Evolution of cell type specific specialized metabolismC Robin Buell University of Georgia USA11 00 11 15Induced genetic variation Precision breeding utilizing conventional breeding technologiesAgnieszka Nielsen Traitomic Carlsberg Group Denmark11 15 11 45Transcriptional regulation of photosynthesisAndrea Br utigam Bielefeld University GermanyNot available on demand11 45 12 00Unveiling the green code benchmarking gene prediction tools and analyzing factors shaping precise annotation in plant genomesQussai Abbas Technical University of Munich Germany12 00 13 30Lunch13 30 16 30Session 5 Plants in their environmentChaired by Anna Ihnatowicz University of Gdansk Poland13 30 14 00My model organism eats your model organism a Drosophila that attacks Arabidopsis leads to a plant size locusNoah Whiteman University of California Berkeley USA14 00 14 15Variance in drought tolerance in the European oak genotypes from German forestsTetyana Nosenko Helmholtz Zentrum M nchen Germany14 15 14 30Interspecies pathway engineering to investigate the immune function of Trp derived specialized metabolismGopal Singh Polish Academy of Sciences Poland14 30 15 00Coffee Break and Meet the speakers with C Robin Buell Andrea Br utigam Noah Whiteman Tonni Grube Andersen 15 00 15 30Cellular lockdowns plasmodesmal regulation of trade offs between growth and defence in plantsChristine Faulkner John Innes Centre UK15 30 15 45Structural features of receptor like proteins RLPs enable versatile immune recognitionAdam Steinbrenner University of Washington USA15 45 16 15Evolution sub functionalisation and regulation of biosynthetic gene clustersClaude Becker Ludwig Maximilians University of Munich Germany16 15 16 30Spatio temporal chemical modulation of root associated microbial communities in the Brassicaceae familyAndra Octavia Roman Max Planck for Plant Breeding Research Germany16 30 17 00Flash talks even numbers 42 Rachna Behl 48 Arpita Chowdhury 50 Douglas Domingues 62 Jian Feng Mao 72 Santiago Priego Cubero17 00 18 30Poster Session 2 even numbers with beer and snacks18 30 20 30Conference dinner20 30 23 00Conference party Day 4 Friday 12 April 2024 Time Europe Berlin Speaker09 00 11 45Session 6 Evolution of phenotypes Chaired by Claude Becker Ludwig Maximilians Universit t M nchen Germany 09 00 09 30Thoughts on the evolution of the sporophyteJohn Bowman Monash University Australia09 30 09 45Creating a genomic and molecular toolbox to assess whether gene duplication has allowed for higher morphological diversity in Begonia Lucy Turnbull University of Edinburgh Royal Botanical Gardens of Edinburgh UK09 45 10 00Comparative transcriptomic analysis of the fern group reveals the evolution of cell wall modulesMarek Mutwil Nanyang Technological University Singapore10 00 10 30Coffee Break and Meet the speakers with Christine Faulkner John Bowman Edwige Moyroud 10 30 10 45Stoma to stomach the evolutionary connection of guard cells and gland cells in cephalotus follicularisDorothea Graus University of W rzburg Germany10 45 11 00A single cell transcriptomic approach to decode the evolutionary innovation of stomatal form and function in a model grassLea Berg University of Bern SwitzerlandNot available on demand11 00 11 30All bullseyes great and small understanding the development and evolution of petal patterning in HibiscusEdwige Moyroud University of Cambridge UK11 30 11 45Closing Remarks and Poster Prize Announcements11 45Packed Lunch and departure Practical information Registration fees and abstract submission On site registration fees include admission conference materials meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Virtual registration fees include access to all of the talks livestreamed and on demand and facility to submit questions On site Academia 725On site PhD Student 625On site Industry 925On site Journal Editors 300Virtual Academia 225Virtual PhD Student 175Virtual Industry 275 Editors from scientific journals are allowed to attend at a reduced rate but asked to contribute to the conference in return by taking part in meet the editors sessions or other planned activities within the programme A letter to support your visa application will be issued on request once payment of the registration fee is confirmed We recommend that you book your visa appointment as soon as possible to avoid any delay with your visa application Accredited journalists may be eligible to register for complimentary press registration Registrants may be required to provide accreditation or equivalent proof of press membership after registration Please contact Nathalie Sneider for more information Please note that we do not offer complimentary registrations for editors of scientific journals Confirmation and payment Registration will be on a first come first served basis Your place can only be confirmed after payment of the registration fee If you are added to our waiting list please consider taking advantage of our offerings to participate virtually On site participants Types of payments accepted are international bank transfers and credit card payments Virtual participants We are only able to accept card payments In exceptional cases we can accept bank transfers Please contact events embl de for details Abstract submission Only participants registering to attend the on site event are eligible to submit an abstract Abstracts will not be accepted from virtual participants After registration you can submit your abstract via a separate link that will be provided in the email confirmation Alternatively you can access the link on the confirmation page directly after registering The same login credentials are used for both processes Please note Abstract body The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised Title The title should not exceed 20 words Only the first word of the title should start with a capital letter and the rest should be lowercase Authors and affiliations Please fill in the author s details as requested in the online form The compulsory fields are First Name Last Name Organisation Name Affiliation or Company Country and Email Kindly mark only one author in the role of First Author and please don t forget to indicate who will be the Presenter Please enter your co authors correctly via the system by adding accounts together with their organisation institute Do not copy paste them into the body of the abstract text as they will not be indexed in the abstract book Presentation types When submitting your abstract you can apply for an oral or poster presentation A selection process will take place with the results announced 2 3 weeks after the abstract submission deadline For detailed instructions on how to submit a conference abstract follow the instructions provided in this video Please check our FAQs pages for further information on how to submit an abstract Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of registration fee waivers travel grants and childcare grants Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course or conference Travel grant The travel grant will cover the cost of travel to an on site event airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from within Europe up to 1000 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from outside Europe up to 500 for any participant travelling to an EMBO Workshop up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Workshop up to 700 for any participant working in Croatia Czech Republic Estonia Greece Hungary Italy Lithuania Luxembourg Poland Slovenia and Turkey travelling to an EMBO Workshop Registration fees are only covered for EMBO Workshops The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant There is the possibility to apply for a childcare grant to offset child care costs incurred by participants speakers and organisers when attending a conference Eligible costs include but are not limited to fees for a baby sitter or child care facility and travel costs for a caregiver Please note that priority will be given to early stage researchers In order to apply for this grant you must be registered by the abstract submission deadline There is a limited amount of funding available for the childcare grants and funds will be distributed amongst eligible applicants Application On site participants You may apply for financial assistance when submitting your abstract In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Virtual participants If you are attending virtually you can apply for financial assistance in the submission portal by the abstract deadline Read the instructions on how to apply for financial assistance Only submissions for financial assistance will be accepted Presentation abstracts cannot be submitted here and will be declined In your application you will be asked to summarise your current work answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Selection The scientific organisers will select the recipients of registration fee waivers and travel grants during the motivation letter or abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection for registration fee waivers and travel grants is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Childcare grants will be allocated in the same timeframe 6 8 weeks before the event start date Please note that priority will be given to early stage researchers Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details View our list of external funding opportunities and information on attending a conference as an event reporter For further information about financial assistance please refer to the FAQ page Accommodation and travel Accommodation is not included in the conference registration fee The hotels below have rooms on hold for participants until Monday 11 March 2024 in some cases at special rates Please email the hotel directly quoting the booking code EES24 04 to confirm the exact price of the room Hotel AnlageHotel ibis HeidelbergSteffi s Hostel HeidelbergHotel Bayrischer Hof Leonardo Hotel Heidelberg City CentreHotel Vier Jahreszeiten HeidelbergB B HotelHotel MonptiExzellenz HotelPremier Inn Heidelberg CityHotel Holl nder Hof Staycity Aparthotel Heidelberg Travel information For travel information please see here If you are travelling to the conference within Germany then you are eligible for the Deutsche Bahn Event Ticket called the Veranstaltungsticket in German This will result in a lower ticket price if your travel distance to Heidelberg is more than 100 km You need to provide proof of your event attendance when purchasing the ticket For more information in English see here or in German see here You can book your ticket here Conference shuttle buses Conference shuttle buses are free of charge for participants and depart from designated bus stops near the hotels to EMBL and back mornings and evenings Please find the bus schedule here The bus stops for this conference are Staycity Aparthotel Speyerer Str 7 Kurf rsten Anlage Opposite Main Train Station Premier Inn Kurf rsten Anlage 23 Leonardo Hotel Heidelberg City Center Bergheimer Str 63 Neckarm nzplatz Heidelberg Tourist Information Peterskirche Bus stop ISG Hotel Im Eichwald 19 View Conference shuttle bus stops and hotels in a larger map Please note that not every bus stop will be used for every event Further details Address EMBL Meyerhofstra e 1 69117 Heidelberg Germany For more information about accommodation and travel please refer to the FAQ page On site information Catering All meals and coffee breaks are included in the registration fee Our catering staff will prepare a wide variety of vegetarian meals meat and fish dishes soups pasta fresh fruit and vegetables as well as a variety of desserts Please wear your badge at all times when serving yourself No food or drinks are allowed in the auditorium Charging lockers There are lockers available next to the stairs leading down into the Auditorium You will find some of those equipped with sockets to charge your smartphone tablet etc Electricity and charging station In most places the electricity is 220 volts AC 50 cycles An adaptor and a plug that fits the German socket may be needed for your appliances laptop i e American Japanese etc A USB charging station for electronic devices is available at the registration desk EMBL merchandise If you are interested in purchasing EMBL merchandise products presented in the glass display in the registration area please email the EMBL shop to place an order or get in contact with your Course Organiser Kindly note the EMBL shop is only open upon request and all purchases must be made in cash Euros only Health and safety notes Please read EMBL s COVID 19 safety policy for on site events Do not smoke in any EMBL building Eating and drinking is prohibited in the Auditorium and all laboratories Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required The first aid room is located next to the ATC Registration Desk room 10 205 Dial the Emergency number 222 from any EMBL internal phone only Where is the accident What happened How many injured Emergency number 06221 387 7821 from mobile phones Please report all accidents to the conference officer at the registration desk In case of fire Press the nearest fire alarm button or the Emergency number 222 from any internal phone A loud fire alarm will go off if an evacuation is required On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting points Do not use the lifts Beyond first aid Please remember to bring your own medication if needed to the conference Note that the next pharmacy is a 4 minute drive from the EMBL but for many medications you will be required to see a doctor to get a prescription Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg In any case the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary Internet Wi Fi is available on campus using the EMBL Events network and the event specific password which will be provided on site The eduroam network secure worldwide roaming access service developed for the international research and education community is also available Lost and found Lost and Found items are kept at the registration desk until the end of the conference Luggage There are lockers available on site to store your luggage which require a 2 EURO coin to operate There is another luggage room on level E0 which is free to use but remains unlocked during the conference Nursing room There is a nursing room available in the ATC Rooftop Lounge on level A29 Photography During the conference an EMBL Photographer may be taking photos If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Printing We can help to print your boarding pass train ticket Please send it to events embl de and collect your print outs at the registration desk Room for prayer yoga and meditation There is a room for prayer meditation and yoga located on level E0 behind the Auditorium Please be respectful of others using the room Sightseeing A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing Travel to and from the venue During the event we provide conference shuttle buses to and from EMBL In addition there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time Information on the conference shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page Useful German expressions HelloHalloGoodbyeAuf Wiedersehen formal Tsch ss informal Good morningGuten MorgenGood afternoonGuten TagGood eveningGuten AbendGood nightGute NachtI m sorryEs tut mir leidExcuse me Entschuldigen SieHow are you Wie gehts I m fine thanks And you Mir geht es gut danke Und Dir Ihnen What is your nameWie hei en Sie formal Wie hei t Du informal My name isIch hei e Do you speak EnglishSprechen Sie englisch I don t understandIch verstehe nichtPlease speak more slowlyK nnen Sie bitte langsamer sprechenThank youDankesch nWhere is the toilet Wo ist die Toilette Please call me a taxiBitte rufen Sie mir ein TaxiHow do I get to Wie komme ich zum zur A beer two beers pleaseEin Bier zwei Bier bitteA glass of red white wine pleaseEin Glas Rot Weisswein bitteThe menu pleaseDie Speisekarte bitteIs there a local speciality Gibt es eine Spezialit t aus dieser Gegend I m vegetarianIch bin VegetarierIt was deliciousEs war hervorragendThe bill pleaseDie Rechnung bitteI have a headacheIch habe KopfschmerzenI have a sore throatIch habe HalsschmerzenMy stomach hurtsIch habe MagenschmerzenI m allergic toIch bin allergisch gegenI need a doctor who speaks EnglishIch brauche einen Arzt der englisch spricht Virtual participation What s included Access to all the livestreamed talks Video library of the recorded talks during the event and for two weeks afterwards Please note at the request of individual speakers some talks are not recorded Facility to submit questions Talks will only be recorded upon speaker s consent Please note that only on site participants are able to submit abstracts and participate in the poster sessions Event platform We are using an event platform for this conference More information about the platform will be shared ahead of the conference Guidelines Do not broadcast the conference to unregistered participants You are encouraged to tweet and post about the event Tweet unless the speaker specifically says otherwise but be mindful of unpublished data Please do not capture transmit or redistribute data presented at the meeting Additional information can be found in our Code of Conduct Health and well being It is important to stay healthy and move around especially when you are attending an event virtually We have put together a few coffee break stretches and yoga videos in the conference platform for you to enjoy during the event How to ask questions Please use the Q A function in the event platform If you have any other questions you can go to the Help Desk in the event platform Click on more on the top menu and click Help Desk Time zone The programme is planned based on the Europe Berlin time zone unless otherwise stated Please take your time zone into consideration when planning your attendance Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for participants page COVID 19 related questions COVID 19 information for on site events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Event sponsor ABclonal Germany Media partners EMBO Journal an EMBO Press Journal FEBS Open Bio International Union of Biochemistry and Molecular Biology Medinformatics a Bon View Publishing journal Open Biology a Royal Society journal PLOS Biology a PLOS journal Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de About EMBO EMBL Symposia promote scientific communication and collaboration in the European research area They provide scientists with a platform to discuss and exchange ideas on forward looking topics and new developments in the life sciences Topics emphasise upcoming developments and the interdisciplinary nature of related fields Jointly funded and organised by EMBO and EMBL and complementary to their respective courses workshops and conference programmes the symposia promote scientific communication and collaboration All symposia are held in the EMBL Advanced Training Centre ATC in Heidelberg Germany or virtually Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9 Leaderboard 728 90...

Barbara Ann Halkier, Sarah E. O’Connor, Detlef Weigel

EMBO | EMBL Symposium

EMBL Heidelberg, Virtual

8 April - 12 April 2024

scATAC-seq: attacking open chromatin in single cells

Edit

April 08, 2024 00:002024CourseEMBL Heidelberg

Description OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview Course overview ATAC Seq stands for Assay of Transposase Accessible Chromatin and is a widespread method to profile open chromatin on a genome scale The goal of this introductory course is to teach the entire workflow of a single cell ATAC Seq experiment including library preparation sequencing data processing and downstream analysis by addressing a real biological question that will be answered at the end of the course We will start with the experimental single cell ATAC Seq protocol highlighting the critical steps potential pitfalls and the most up to date tweaks to improve the quality of the results After sequencing the samples we will go through the basic quality control and preprocessing steps using multiple analysis tools for next generation sequencing data Finally we will perform different types of analysis on the processed data including visualisation differential peak calling and differential transcription factor activity profiling to come to a biological conclusion In addition we will discuss recent advancements in technology development and algorithms for joint analysis of scRNA and scATAC seq data how to use these joint modalities to generate gene regulatory networks and give an outlook on future perspectives and applications including ways for multiplexing scRNA scATAC assays and high throughput cost effective options Audience This course is directed towards molecular biologists who want to perform scATAC Seq experiments and or analysis in their lab Learning outcomes After this course you should be able to Perform complete flow for single cell ATAC Seq experiments Process and quality control of single cell ATAC Seq data Visualise the data and call differences between samples Analyse and interpret the data using existing tools What past participants say about the course A very well tailored course with fantastic speakers who take you on an exciting journey from wet lab to data analysis Mahdi Adam Mickiewicz University Poland It was an intense but very informative and motivating week Both the theoretical and practical parts were perfectly organised Thank you for the price worthy experience Kristyna Zavacka Masaryk University Czech Republic Speakers Christian Arnold EMBL Heidelberg Germany Gwen Bauersachs EMBL Heidelberg Germany Vladimir Benes EMBL Heidelberg Germany Ivan Berest ETH Z rich Switzerland Annique Claringbould EMBL Heidelberg Germany Michael Dorrity EMBL Heidelberg Germany Charles Dussiau EMBL Heidelberg Germany Cyndie Forestier Element Biosciences France Juan Jauregui EMBL Heidelberg Germany Dirk J rgensen 10X Genomics Germany Maksim Kholmatov EMBL Heidelberg Germany Ulrike Litzenburger Nuvisan Innovation Campus Berlin Germany Sara Lobato Moreno EMBL Heidelberg Germany Kristy Ou EMBL Heidelberg Germany Hilal Ozgur EMBL Heidelberg Germany Karin Prummel EMBL Heidelberg Germany Nila Servaas EMBL Heidelberg Germany Evi Vlachou EMBL Heidelberg Germany Daphne Welter EMBL Heidelberg Germany Judith Zaugg EMBL Heidelberg Germany Katharina Zirngibl Heidelberg University Germany Jan Provaznik EMBL Heidelberg Germany Scientific organisers Vladimir Benes EMBL Heidelberg Germany Ulrike Litzenburger Nuvisan Innovation Campus Berlin Germany Judith Zaugg EMBL Heidelberg Germany Course organisers Inna B sselmann Course and Conference Manager EMBL Heidelberg Germany Irena Provaznikova Scientifc Training Manager EMBL Heidelberg Germany Programme Are you on social media Post using EMBLATAC and don t forget to tag EMBLEvents Day 1 Monday 8 April 2024 TimeSpeakerLocation08 40Bus from ISG Hotel to EMBLISG Hotel entrance09 00 09 45Welcome introduction and safety briefingVladimir Benes EMBL Heidelberg GermanyUlrike Litzenburger Nuvisan Innovation Campus Berlin GermanyJudith Zaugg EMBL Heidelberg GermanyCourtyard Room A B09 45 10 45Participants flash talksCourtyard Room A B10 45 11 00Coffee break11 00 11 45Experimental practical Introduction and preparation to experimental practicalGwen Bauersachs EMBL Heidelberg GermanyUlrike Litzenburger Nuvisan Innovation Campus Berlin GermanyTraining Lab A B11 45 12 45LunchEMBL Canteen 12 45 14 45 Experimental practical Sample preparation and transpositionGwen Bauersachs EMBL Heidelberg GermanyJuan Jauregui EMBL Heidelberg GermanySara Lobato Moreno EMBL Heidelberg GermanyHilal Ozgur EMBL Heidelberg GermanyKarin Prummel EMBL Heidelberg GermanyDaphne Welter EMBL Heidelberg GermanyTraining Lab A B14 45 17 30Experimental practical with flexible coffee break GEM formation and elongationGwen Bauersachs EMBL Heidelberg GermanyJuan Jauregui EMBL Heidelberg GermanySara Lobato Moreno EMBL Heidelberg GermanyHilal Ozgur EMBL Heidelberg GermanyKarin Prummel EMBL Heidelberg GermanyDaphne Welter EMBL Heidelberg GermanyTraining Lab A B17 30 17 45Coffee break17 45 18 15Seminar Nuclei isolation Tips and Tricks Karin Prummel EMBL Heidelberg GermanyCourtyard Room A B18 15 19 00Lecture Single cells ATAC Seq introduction Ulrike Litzenburger Nuvisan Innovation Campus Berlin GermanyEMBL Canteen19 00 20 15DinnerEMBL Canteen 20 15Bus from EMBL to ISG Hotel Day 2 Tuesday 9 April 2024 TimeSpeakerLocation08 40 Bus from ISG Hotel to EMBLISG Hotel entrance09 00 12 00Experimental practical with flexible coffee break Breaking GEMs and library preparationGwen Bauersachs EMBL Heidelberg GermanyJuan Jauregui EMBL Heidelberg GermanySara Lobato Moreno EMBL Heidelberg GermanyHilal Ozgur EMBL Heidelberg GermanyKarin Prummel EMBL Heidelberg GermanyDaphne Welter EMBL Heidelberg GermanyTraining Lab A B12 00 13 00LunchEMBL Canteen 13 00 13 10Results explanationUlrike Litzenburger Nuvisan Innovation Campus Berlin GermanyTraining Lab A B13 10 14 00 Lecture Cyndie Forestier Element Biosciences FranceCourtyard Room A B14 00 15 40 Bioanalyzer results explained Gwen Bauersachs EMBL Heidelberg GermanyKarin Prummel EMBL Heidelberg GermanyHilal Ozgur EMBL Heidelberg GermanyCourtyard Room A B15 00 15 40Coffee break and GeneCore tourGeneCore15 40 16 00Start of sequencing run16 00 16 30Coffee break and Q AFoyer16 30 19 30Students presentations pizzaCourtyard Room A B19 30Bus from EMBL to ISG HotelATC entrance Day 3 Wednesday 10 April 2024 TimeSpeakerLocation08 40Bus from ISG Hotel to EMBLISG Hotel entrance09 00 10 00Lecture Sample Preparation for scATAC Assay What are important factorsDirk J rgensen 10X Genomics GermanyCourtyard Room A B10 00 10 45Lecture A multimodal approach to identify molecular drivers of follicular lymphoma transformationKristy Ou EMBL Heidelberg GermanyCourtyard Room A B10 45 11 00Coffee break11 00 11 45Lecture Overview of computational methods for integrating scATAC Seq and scRNA seqJudith Zaugg EMBL Heidelberg GermanyCourtyard Room A B11 45 12 30Lecture sequencing technologiesVladimir Benes EMBL Heidelberg GermanyCourtyard Room A B12 30 13 30LunchEMBL Canteen 13 30 14 00Students presentations IICourtyard Room A B14 00 14 30Group photo and coffee break14 30 16 00Computational practical Introduction to Linux R and computational analysesChristian Arnold EMBL Heidelberg GermanyIvan Berest ETH Z rich SwitzerlandAnnique Claringbould EMBL Heidelberg GermanyMaksim Kholmatov EMBL Heidelberg GermanyComputer Training Lab16 00 16 30Lecture AVITI data pre processing Jan Provaznik EMBL Heidelberg GermanyComputer Training Lab16 30 18 30Computational practical Start computational analysis overnightChristian Arnold EMBL Heidelberg GermanyIvan Berest ETH Z rich SwitzerlandAnnique Claringbould EMBL Heidelberg GermanyMaksim Kholmatov EMBL Heidelberg GermanyComputer Training Lab18 30 19 30DinnerEMBL Canteen19 30 Bus from EMBL to ISG HotelATC entrance Day 4 Thursday 11 April 2024 TimeSpeakerLocation08 40Bus from ISG Hotel to EMBLISG Hotel entrance09 00 10 30 Computational practical with flexible coffee break Christian Arnold EMBL Heidelberg GermanyIvan Berest ETH Z rich SwitzerlandAnnique Claringbould EMBL Heidelberg GermanyMaksim Kholmatov EMBL Heidelberg GermanyKristy Ou EMBL Heidelberg GermanyNila Servaas EMBL Heidelberg GermanyKatharina Zirngibl University Heidelberg GermanyCharles Dussiau EMBL Heidelberg GermanyEvi Vlachou EMBL Heidelberg GermanyComputer Training Lab10 30 12 30Computational practicalChristian Arnold EMBL Heidelberg GermanyIvan Berest ETH Z rich SwitzerlandAnnique Claringbould EMBL Heidelberg GermanyMaksim Kholmatov EMBL Heidelberg GermanyKristy Ou EMBL Heidelberg GermanyNila Servaas EMBL Heidelberg GermanyKatharina Zirngibl University Heidelberg GermanyCharles Dussiau EMBL Heidelberg GermanyEvi Vlachou EMBL Heidelberg GermanyComputer Training Lab12 30 13 30LunchEMBL Canteen 13 30 14 00Lecture Overview of scATAC computational analysesIvan Berest ETH Z rich SwitzerlandComputer Training Lab14 00 16 00Computational practicalChristian Arnold EMBL Heidelberg GermanyIvan Berest ETH Z rich SwitzerlandAnnique Claringbould EMBL Heidelberg GermanyMaksim Kholmatov EMBL Heidelberg GermanyKristy Ou EMBL Heidelberg GermanyNila Servaas EMBL Heidelberg GermanyKatharina Zirngibl University Heidelberg GermanyCharles Dussiau EMBL Heidelberg GermanyEvi Vlachou EMBL Heidelberg GermanyComputer Training Lab16 00 16 30Coffee break16 30 18 30Computational practicalChristian Arnold EMBL Heidelberg GermanyIvan Berest ETH Z rich SwitzerlandAnnique Claringbould EMBL Heidelberg GermanyMaksim Kholmatov EMBL Heidelberg GermanyKristy Ou EMBL Heidelberg GermanyNila Servaas EMBL Heidelberg GermanyKatharina Zirngibl University Heidelberg GermanyCharles Dussiau EMBL Heidelberg GermanyEvi Vlachou EMBL Heidelberg GermanyComputer Training Lab18 40Bus from EMBL to downtownATC entrance19 30Course dinner downtown at Oskar restaurantRestaurant Day 5 Friday 12 April 2024 TimeSpeakerLocation08 40Bus from ISG Hotel to EMBLISG Hotel entrance09 00 09 30Lecture Applications of sc ATAC seq to understand zebra fish in developmentMike Dorrity EMBL Heidelberg GermanyComputer Training Lab09 30 12 00Computational practical with flexible coffee break Christian Arnold EMBL Heidelberg GermanyIvan Berest ETH Z rich SwitzerlandAnnique Claringbould EMBL Heidelberg GermanyMaksim Kholmatov EMBL Heidelberg GermanyKristy Ou EMBL Heidelberg GermanyNila Servaas EMBL Heidelberg GermanyKatharina Zirngibl University Heidelberg GermanyCharles Dussiau EMBL Heidelberg GermanyEvi Vlachou EMBL Heidelberg GermanyComputer Training Lab12 00 13 00 LunchEMBL Canteen 13 00 14 00Participants prepare for presentationsComputer Training Lab14 00 14 30Coffee break14 30 16 00Presentation of results by participantsComputer Training Lab16 00 16 30Wrap up end of the course and departureComputer Training Lab16 30Bus downtown to Heidelberg train stationATC entrance Practical information Registration fees and motivation letter The course is limited to 18 participants For selection purposes please note that your application will not be considered without a letter of motivation Registration Registration fees include admission course materials COVID 19 safety measures meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Academia 715PhD Student 715Industry 1225 NO visa support letters will be issued until payment of the registration fee is confirmed Confirmation and payment The registration fee should be paid only after acceptance to the course The results will be announced approximately 2 3 weeks after the application deadline Motivation letter submission After you have logged in and successfully registered you will receive an email asking you to submit your motivation letter Click on the link provided and enter your motivation letter in the text box provided Alternatively you can submit your motivation letter by clicking on the link on the confirmation page directly after registering Instructions Include your relevant skills experience and qualifications showing why you would be suitable for the course Explain why you would like to attend including what you can contribute and how you think you will benefit from the course Please note The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised For detailed instructions please watch our video on how to submit a course motivation letter Further details For further information about registration and motivation letter submission please refer to the FAQ page Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of registration fee waivers travel grants and childcare grants Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course Travel grant The travel grant will cover the cost of travel airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Course within Europe up to 1000 for participants travelling to an EMBL Course from outside Europe up to 500 for any participant travelling to an EMBO Practical Course up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Practical Course up to 700 for any participant working in Croatia Czech Republic Estonia Greece Hungary Italy Lithuania Luxembourg Poland Slovenia and Turkey travelling to an EMBO Practical Course Registration fees are only covered for EMBO Practical Courses The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant There is the possibility to apply for a childcare grant to offset child care costs incurred by participants speakers trainers and organisers when attending a course Eligible costs include but are not limited to fees for a babysitter or child care facility and travel costs for a caregiver Please note that priority will be given to early stage researchers There is a limited amount of funding available for the childcare grants and funds will be distributed amongst eligible applicants Boehringer Ingelheim Fonds travel grant Applies to selected courses only Availability will be indicated during the motivation letter submission process This grant covers costs related to your attendance at the course registration travel and accommodation costs The grant is restricted to PhD students and postdocs who conduct basic biomedical research Whether you are eligible to apply for a travel grant depends on when you received your university entrance qualification e g Abitur A Levels High School Diploma Final State Examination for PhD and MD students as well as graduates the university entrance qualification must not have been obtained more than 11 years ago at the time of the envisaged course for postdocs the university entrance qualification must not have been obtained more than 13 years ago at the time of the envisaged course Application You may apply for financial assistance when submitting your motivation letter for courses In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application For the Boehringer Ingelheim Fonds Travel Grant there is a pre application question during the motivation letter submission process and if selected you will be requested to complete a standard form and documentation consisting of your travel expense estimation Selection The scientific organisers will select the recipients of all financial assistance during the motivation letter selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the course Selection is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details See our list of external funding opportunities and for further information about financial assistance please refer to the FAQ page Accommodation and travel Travel information For travel information please see here If you are travelling to the conference within Germany then you are eligible for the Deutsche Bahn Event Ticket called the Veranstaltungsticket in German This will result in a lower ticket price if your travel distance to Heidelberg is more than 100 km You need to provide proof of your event attendance when purchasing the ticket For more information in English see here or in German see here You can book your ticket here Accommodation is not included in the registration fee Participants are expected to book and pay for their own accommodation A mix of single and twin rooms have been reserved for 5 nights 7 12 April 2024 at the ISG Hotel Single rooms are limited and will be available on a first come first served basis After the selection process selected participants should contact the hotel directly to make a booking with a booking code ATA24 01 by the deadline of 11 March 2024 We recommend that all course participants stay in the dedicated hotel for the course Local transport Shuttle buses will go from the ISG Hotel to EMBL and back mornings and evenings A bus schedule and location of the bus stops will be made available prior to the meeting Further details Address EMBL Heidelberg Meyerhofstra e 1 69117 Heidelberg GermanyFor more information about accommodation and travel please refer to the FAQ page On site information Catering All meals and coffee breaks are included in the registration fee Our catering staff will prepare a wide variety of vegetarian meals meat and fish dishes soups pasta fresh fruit and vegetables as well as a variety of desserts Please wear your badge at all times when serving yourself No food or drinks are allowed in the laboratories Electricity and charging station In most places the electricity is 220 volts AC 50 cycles An adaptor and a plug that fits the German socket may be needed for your appliances laptop i e American Japanese etc A USB charging station for electronic devices is available at the registration desk EMBL Merchandise If you are interested in purchasing an EMBL souvenir products presented in the glass display in the registration area please ask at the registration desk for more information Health and safety notes Please read EMBL s COVID 19 safety policy for on site events Do not smoke in any EMBL building Eating and drinking is prohibited in all laboratories Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required The first aid room is located next to the ATC Registration Desk room 10 205 Dial the Emergency number 222 from any EMBL internal phone only Where is the accident What happened How many injured Emergency number 06221 387 7821 from mobile phones Please report all accidents to the conference officer at the registration desk In case of fire Press the nearest fire alarm button or the Emergency number 222 from any internal phone A loud fire alarm will go off if an evacuation is required On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting points Do not use the lifts Beyond first aid Please remember to bring your own medication if needed to the conference Note that the next pharmacy is a 4 minute drive from the EMBL but for many medications you will be required to see a doctor to get a prescription Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg In any case the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary Internet Wi Fi is available on campus Log in using the EMBL Events network and the event specific password which will be provided on site The eduroam network secure worldwide roaming access service developed for the international research and education community is also available Lost and found Lost and Found items are kept at the registration desk until the end of the conference Luggage There are lockers available on site to store your luggage which require a 2 EURO coin to operate There is another luggage room on level E0 which is free to use but remains unlocked during the conference Nursing room There is a nursing room available in the ATC Rooftop Lounge on level A29 Photography During the conference an EMBL Photographer may be taking photos If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Printing We can help to print your boarding pass train ticket Please send it to events embl de and collect your print outs at the registration desk Room for prayer yoga and meditation There is a room for prayer meditation and yoga located on level E0 behind the Auditorium Please be respectful of others using the room Sightseeing A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing Travel to and from the venue During the event we provide conference shuttle buses to and from EMBL In addition there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time Information on the shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page Map to walk from ISG Hotel to EMBL Additional information Address EMBL Heidelberg Meyerhofstra e 1 69117 Heidelberg Germany ATC orientation map Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page Event software The EMBL eCampus learning platform will be used to collaborate communicate and network with all of the course participants All participants will receive information on how to join shortly before the course We recommend using Chrome Safari or Mozilla Firefox browsers for eCampus Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page COVID 19 related questions COVID 19 information for on site events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors course partner course sponsor Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other events or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1600 900 PPT Slide 16 9...

Vladimir Benes, Ulrike Litzenburger, Judith Zaugg

EMBL Heidelberg

8 April - 12 April 2024

Data-driven approaches to understanding dementia

Edit

April 08, 2024 00:002024CourseEMBL-EBI

Description This course provides individuals working in dementia research with the skills to access and analyse dementia data Participants will learn to apply bioinformatics methodologies combine different data types and utilise relevant dementia data resources enhancing their research capabilities in the field...

Juanita Riveros

EMBL-EBI

28 March 2024

Explore Human Pangenome Reference Consortium (HPRC) data in Ensembl

Edit

March 28, 2024 15:302024WebinarVirtual

Description The Human Pangenome Reference Consortium HPRC aims to construct a comprehensive and representative human pangenome reference to better illustrate the genomic landscape of diverse human populations In this webinar we will guide you on how to access HPRC data via the Ensembl genome browser We will explore the available gene annotation and genetic variation data of the sequence assemblies produced by the project...

Virtual

27 March 2024

The Pathogens Portal: A gateway to vast biomolecular data for pathogen research

Edit

March 27, 2024 15:302024WebinarVirtual

Description The COVID 19 pandemic starkly illuminated the crucial role of open biodata in combating infectious diseases EMBL EBI recognising this significance swiftly launched the COVID 19 Data Portal a centralised repository for SARS CoV 2 related biomolecular data Building upon this success the Pathogens Portal emerges as the spiritual successor expanding its scope to encompass a broader spectrum of pathogens The Pathogens Portal serves as a comprehensive resource for researchers clinicians and policymakers seeking access to a wealth of biomolecular data related to a diverse range of pathogens It aims to facilitate rapid knowledge discovery accelerate disease prevention and treatment strategies and foster collaboration across the scientific community This webinar introduces the Pathogens Portal to users demonstrating the why and how it exists how we decide what pathogens are included as well as a tour of the features in the portal It will deepen participants understanding of how to use the portal and introduce features that are part of the broader platform such as the datahubs a system for sharing data in a controlled access environment You may either watch the entire presentation from the introduction or navigate directly to a specific section by clicking the links provided below Introduction to the pathogens portalWhat data types are included in the portalPathogens portal tourSearching and browsing dataQ A...

Virtual

20 March 2024

Microbial biodiversity at schools and its link with children’s health

Edit

March 20, 2024 15:302024WebinarVirtual

Description There is a wealth of microbial diversity in the environment in soil on plants and in the atmosphere Urbanisation usually involves disturbance and sealing of soil along with a decrease and alteration of vegetation This process drastically reduces natural microbial sources such as soil and phyllosphere leaf surfaces which also contribute to enriching the atmosphere Nevertheless in an urban environment other microbial sources are more common such as wastewater treatment trash and human associated microbes Significant differences have been observed in the environmental microbial communities between urban and non urban environments Several hypotheses highlight the importance of contact with diverse natural microbial communities for human health especially for children In this webinar using a case study of the Belgian B SEBALL project we will illustrate how to investigate microbial biodiversity at school playgrounds and its potential contribution to different aspects of children s health This case study showcases the possibilities and limits of 16S rRNA amplicon sequencing in the context of the biodiversity hypothesis Does microbial diversity benefit human health The answer seems to be more nuanced than expected We will also demonstrate the power of adjusting and generating hypotheses based on field microbiome data You may either watch the entire presentation from the introduction or navigate directly to a specific section by clicking the links provided below IntroductionCharacteristics of urban environments associated with urban diseasesThe human microbiome and its importanceMicrobiomes connecting One healthThe biodiversity hypothesisInvestigating the biodiversity hypothesis in Belgian schoolsQ A...

Virtual

19 March - 21 March 2024

Metabarcoding and data sharing for environmental DNA

Edit

March 19, 2024 00:002024CourseVirtual

Description This course will demonstrate applying metabarcoding analysis to eDNA for assessing biodiversity Sequencing DNA barcodes from mixed sources of DNA is being increasingly used to survey biodiversity whether analysing dietary content from faecal derived DNA or monitoring aquatic species from water derived DNA This course will give an overview of metabarcoding with different barcoding genes to target particular taxa Using an example data set we will go from raw sequence data through to assigning taxonomy to the sequence variants and some examples of downstream community analysis Sessions will comprise presentations and self paced computer practicals guided by an online interactive book containing theory and practice code This virtual course will be delivered via live streamed talks on Zoom with support from instructors via Zoom and Slack during the timetabled sessions Computer practicals will run on a virtual training platform so attendees will not need access to a powerful computer or to install any software We are willing to make reasonable adjustments to facilitate learning where possible and will provide clear routes to enable anyone that requires this to discuss this with us ahead of the training...

Ajay Mishra

Virtual

19 March - 22 March 2024

Biological oscillators: rhythms and synchronisation across scales

Edit

March 19, 2024 00:002024ConferenceEMBL Heidelberg, Virtual

Description OverviewSpeakersProgrammePractical informationSponsorsAboutMedia Kit Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Symposium overview Are you interested to discuss oscillatory phenomena and biological dynamical systems accross temporal and spatial scales At this symposium multiple disciplines will come together in order to discuss common themes linked to oscillations rhythms and synchronization in a broad range of contexts The 2024 edition of this established symposium will expand the discussion to the scale of ecological oscillations and willl also highlight the interplay between internal and environmental rhythms This meeting provides a unique platform to bring together a community working at the interface between quantitative biology complex oscillatory systems modelling and theory As with the editions in 2015 2018 and 2022 this meeting aims to serve as a bridge between experimentalists and theorists and to reveal common challenges and approaches that can be shared across fields Session Topics Oscillation mechanisms across different scales from circadian clock to embryonic oscillators to biochemical metabolic oscillations Oscillation function across scale and context Synchronisation of coupled oscillators Ecological rhythms and oscillations Mathematical modelling and computational approaches Imaging approaches to study oscillatory dynamics Pre symposium workshop Oscillator Theory for Biologists workshop optional Registration and details of this will be announced nearer the date What past participants say about the Symposium As a first time attendant at EMBL conference on Biological oscillations I found the event exceptionally excellent As an interdisciplinary researcher I learned about so many diverse topics and I was even offered a possible postdoc position Hamed Yeganegi Chair of Zoology TUM Munich and GSN LMU Munich Germany It was an exciting conference where new research unexpected results and profound analysis were presented In addition very bold hypotheses were discussed As a result I have new ideas for further research and possible collaborations Nancy Papalopulu F M I Basel Switzerland Speakers Speakers W Tecumseh Fitch University of Vienna Austria Alan Hastings University of California Davis USA Jae Kyoung Kim Institute for Basic Science IBS South Korea Aneta Koseska Max Planck Institue for Neurobiology Behaviour Germany Luis Larrondo Pontificia Universidad Catolica de Chile Chile Andrew Liebhold US Forest Service USA Andrew Charles Oates EPFL cole Polytechnique F d rale de Lausanne Switzerland Carrie Partch University of California Santa Cruz USA Filipa Rijo Ferreira University of California Berkeley USA Maria Robles Ludwig Maximilian University of Munich Germany Akiko Satake Kyushu University Japan Fran ois Schweisguth Institut Pasteur France Jun Yan Chinese Academy of Sciences China Scientific Organisers Alexander Aulehla EMBL Heidelberg Germany Alan Hastings University of California Davis USA Hanspeter Herzel ITB Humboldt University Berlin Germany Carrie Partch University of California Santa Cruz USA Conference organiser Chris Stocks Course and Conference Team Lead EMBL Heidelberg Germany Programme Are you on social media Post using EESBioOsc and don t forget to tag EMBLEvents Please note that the programme is subject to change Some speakers may need to join virtually to give their talk For registered participants recorded talks will be accessible on demand for 2 weeks after the end of the event unless indicated otherwise Day 1 Tuesday 19 March 2024 Time Europe Berlin Speaker12 30 13 45Registration and light refreshments13 45 14 00Opening remarks14 00 18 45Session 1Session Chair Hanspeter Herzel14 00 14 30Opening talk Synchrony in ecology why and howAlan Hastings University of California Davis USA14 30 15 00Oscillatory transients in natural systemsAneta Koseska Max Planck Institute for Neurobiology Behaviour Germany15 00 15 15Metachronal waves in the ciliary band of Platynereis dumerilii larvaeRebecca Poon University of Exeter UK15 15 15 45Coffee break and meet the speakersonsite participants to move to Large Operon 15 45 16 45Lecture Oscillator Theory for BiologistsHanspeter Herzel ITB Humboldt University GermanyVenue Large Operon16 45 17 00Break to prepare Tutorial 17 00 18 00Oscillator Theory 101 Hands on workshop on Biology and TimeMarta del Olmo Institute for Theoretical Biology BerlinZsofia Bujtar Max Delbr ck Center BerlinSaskia Grabe Institute for Theoretical Biology BerlinVenue Large Operon18 00 18 15Break and reconvene in the Auditorium18 15 18 45Circadian rhythms in hosts malaria parasites and their vectorsFilipa Rijo Ferreira University of California USA18 45 20 30Dinner in canteen20 30 22 00After dinner drinks and networking20 00Conference shuttle bus to all stops downtown including ISG21 00Conference shuttle bus to all stops downtown including ISG22 00Conference shuttle bus to all stops downtown including ISG Day 2 Wednesday 20 March 2024 Time Europe Berlin Speaker09 30 12 15Session 2Session Chair Aneta Koseska09 30 10 00Mastering noise in rhythm generation strategies for utilization and avoidanceJae Kyoung Kim Korea Advanced Institute of Science and Technology Republic of Korea10 00 10 15Notch signaling dynamics during small intestine homeostasisSonja Weterings Hubrecht Institute The Netherlands10 15 10 30Delta Cells Modulate Pancreatic Islets Beta Cell Calcium Wave Origin FormationYi Yu Peking University China10 30 11 00Coffee break and meet the speakers11 00 11 15Controlling condensates and through protein oscillationsMathias Luidor Heltberg University of Copenhagen Denmark11 15 11 45These go to eleven pushing period range in eukaryotic clocks a perspective on ultradian as well as fast circadian rhythmsLuis Larrondo P Universidad Catolica de Chile Millennium Institute for Integrative Biology iBio Chile11 45 12 15Organization of cellular network of circadian oscillators in the nervous systemJun Yan Center for Excellence in Brain Science and Intelligence Technology Chinese Acadamy of Sciences China12 15 13 45Lunch and meet the editors 13 45 16 30Session 3Session Chair Ueli Schibler13 45 14 15Periodic oscillations and synchronization of forest insect outbreaks across large spatial scalesAndrew Liebhold USDA Forest Service Northern Research Station USA14 15 14 30Molecular cooperation but functional antagonism how NF B activation perturbs p53 dynamics impairing DNA damage repair process Emanuele Colombo IRCCS Ospedale San Raffaele Italy14 30 14 45Distinct transcriptional oscillators in the circadian neuronal network preferentially synchronize with each otherDeniz Top University of Alberta Canada14 45 15 15Coffee break and meet the speakers15 15 15 30Early birds and slow worms probing links between conserved biological timing mechanisms in nematodes and mammals Rebecca Spangler University of California Santa Cruz United States of America15 30 15 45Uncovering a signaling role of metabolism in mammalian embryos using entrainment based dynamical systems approachHidenobu Miyazawa EMBL Heidelberg Germany15 45 16 00Emergent behavioural complexity in a ciliated microorganismAlexander Boggon University of Exeter UK16 00 16 30Morning larks and night owls shed light on human circadian timekeepingCarrie Partch University of California USA Virtual Speaker 16 30 17 00Flash talks 35 Bitsch Marion 37 Cebri n Lacasa Daniel 39 Combres Lea 41 Montagnac Guillaume 43 Denis Christian 49 Hawley Joshua 53 Kudo Shuichi 59 Naven Mark 63 Pietsch Julian 65 Pei Duanqing 67 Rowntree Andrew 69 Schreiber Igor 73 Stengl Monika 77 Valim Henrique 81 Zajac Olivier17 00 19 00Poster Session 1 odd numbers View poster listing here19 00 20 30Dinner in EMBL Canteen20 30 22 00After dinner drinks20 00Conference shuttle bus to all stops downtown including ISG21 00Conference shuttle bus to all stops downtown including ISG22 00Conference shuttle bus to all stops downtown including ISG Day 3 Thursday 21 March 2024 Time Europe Berlin Speaker09 30 12 30Session 4 Session Chair Alexander Auhlela09 30 10 00On clocks and timers in developmentAndrew Charles Oates EPFL Switzerland10 00 10 15Interrelation of circalunar circadian and photoperiodic time keeping in the marine midge ClunioJule Neumann Max Planck Institute for Evolutionary Biology Germany10 15 10 30A parsimonious mechanism to generate rhythmic gene expression with wide phase dispersionHelge Grosshans Friedrich Miescher Institute for Biomedical Research Switzerland10 30 11 00Coffee break and meet the speakers11 00 11 15Ghost cycles in biological systemsDaniel Koch Max Planck Institute for Neurobiology of Behavior Germany11 15 11 45Spatiotemporal dynamics of the mammalian circadian clock transcriptional active complex at the chromatinMaria Robles Ludwig Maximilians Universit t M nchen GermanyNot available on demand11 45 12 15Self organized patterning in the Drosophila eyeFran ois Schweisguth Institut Pasteur FranceNot available on demand12 15 12 30RBBP5 is an epigenetic regulator of mammalian 12h oscillator and stress responses Bokai Zhu University of Pittsburgh USA12 30 14 00Lunch14 00 16 30Group Activity Hike16 30 17 00Coffee break and meet the speakers17 00 17 30Flash talks 32 Abenza Juan F 34 Avello Paula 44 el Azhar Yasmine 50 Jadhav Dinesh 52 Zambrano Samuel 54 Mishra Nikhil 66 Gelens Lendert 70 Sellier Prono Marie 72 Nunley Hayden 76 Trummel Tabea 78 Weir Kurt 82 Zhu Ruimin17 30 19 30Poster session 2 even numbers View poster listing here19 30 21 00Conference dinner21 00 23 30Conference party with DJ21 30Conference shuttle bus to all stops downtown including ISG22 30Conference shuttle bus to all stops downtown including ISG23 30Conference shuttle bus to all stops downtown including ISG Day 4 Friday 22 March 2024 Time Europe Berlin Speaker09 30 12 15Session 5Session Chair Alan Hastings09 30 09 45Unlocking the rhythm Deciphering the role of rhythmic stability for circadian dynamics through single cell analysis and mathematical modelingMarta Del Olmo Institute for Theoretical Biology Humboldt Universit t zu Berlin and Charit Universit tsmedizin Berlin Berlin09 45 10 00HES1 oscillations offer a new perspective on re emergence from cellular dormancy in breast cancerOliver Cottrell University of Manchester UK10 00 10 30Synchrony from genes to ecosystemsAkiko Satake Kyushu University Japan10 30 11 00Coffee break and meet the speakers11 00 11 15Control of segmentation timing in the zebrafish notochordAdhyapok Priyom Duke University USA11 15 11 30Theoretical analysis of body temperature fluctuation during hibernationShingo Gibo RIKEN Japan11 30 11 45Cytoplasmic oscillations and cytoskeletal dynamics collectively control the cell cycle periodMartina Boiardi KU Leven Belgium11 45 12 15Human rhythmic synchronization in music dance and languageW Tecumseh Fitch University of Vienna Austria12 15 12 30Closing remarks and poster prize announcements12 30 12 45Packed lunch and departure12 45Airport bus to Frankfurt airport13 00Conference shuttle bus to all stops downtown including ISG Practical information Registration fees and abstract submission On site registration fees include admission conference materials meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Virtual registration fees include access to all of the talks livestreamed and on demand and facility to submit questions On site Academia 725On site PhD Student 625On site Industry 925On site Journal Editor 300Virtual Academia 225Virtual PhD Student 175Virtual Industry 275 Editors from scientific journals are allowed to attend at a reduced rate but asked to contribute to the conference in return by taking part in meet the editors sessions or other planned activities within the programme A letter to support your visa application will be issued on request once payment of the registration fee is confirmed We recommend that you book your visa appointment as soon as possible to avoid any delay with your visa application Accredited journalists may be eligible to register for complimentary press registration Registrants may be required to provide accreditation or equivalent proof of press membership after registration Please contact Christopher Stocks for more information Please note that we do not offer complimentary registrations for editors of scientific journals Confirmation and payment Registration will be on a first come first served basis Your place can only be confirmed after payment of the registration fee If you are added to our waiting list please consider taking advantage of our offerings to participate virtually On site participants Types of payments accepted are international bank transfers and credit card payments Virtual participants We are only able to accept card payments In exceptional cases we can accept bank transfers Please contact events embl de for details Abstract submission Only participants registering to attend the on site event are eligible to submit an abstract Abstracts will not be accepted from virtual participants After registration you can submit your abstract via a separate link that will be provided in the email confirmation Alternatively you can access the link on the confirmation page directly after registering The same login credentials are used for both processes Please note Abstract body The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised Title The title should not exceed 20 words Only the first word of the title should start with a capital letter and the rest should be lowercase Authors and affiliations Please fill in the author s details as requested in the online form The compulsory fields are First Name Last Name Organisation Name Affiliation or Company Country and Email Kindly mark only one author in the role of First Author and please don t forget to indicate who will be the Presenter Please enter your co authors correctly via the system by adding accounts together with their organisation institute Do not copy paste them into the body of the abstract text as they will not be indexed in the abstract book Presentation types When submitting your abstract you can apply for an oral or poster presentation A selection process will take place with the results announced 2 3 weeks after the abstract submission deadline For detailed instructions on how to submit a conference abstract follow the instructions provided in this video Please check our FAQs pages for further information on how to submit an abstract Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of registration fee waivers travel grants and childcare grants Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course or conference Travel grant The travel grant will cover the cost of travel to an on site event airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from within Europe up to 1000 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from outside Europe up to 500 for any participant travelling to an EMBO Workshop up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Workshop up to 700 for any participant working in Croatia Czech Republic Estonia Greece Hungary Italy Lithuania Luxembourg Poland Slovenia and Turkey travelling to an EMBO Workshop Registration fees are only covered for EMBO Workshops The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant There is the possibility to apply for a childcare grant to offset child care costs incurred by participants speakers and organisers when attending a conference Eligible costs include but are not limited to fees for a baby sitter or child care facility and travel costs for a caregiver Please note that priority will be given to early stage researchers In order to apply for this grant you must be registered by the abstract submission deadline There is a limited amount of funding available for the childcare grants and funds will be distributed amongst eligible applicants Application On site participants You may apply for financial assistance when submitting your abstract In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Virtual participants If you are attending virtually you can apply for financial assistance in the submission portal by the abstract deadline Read the instructions on how to apply for financial assistance Only submissions for financial assistance will be accepted Presentation abstracts cannot be submitted here and will be declined In your application you will be asked to summarise your current work answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Selection The scientific organisers will select the recipients of all financial assistance during the abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection for registration fee waivers and travel grants is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Childcare grants will be allocated in the same timeframe 6 8 weeks before the event start date Please note that priority will be given to early stage researchers Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details View our list of external funding opportunities and information on attending a conference as an event reporter For further information about financial assistance please refer to the FAQ page Accommodation and travel Accommodation is not included in the conference registration fee As further changes in our events are possible you should book flights trains and hotels with flexible options and favourable cancellation conditions The hotels below have rooms on hold for participants until 20 February 2024 in some cases at special rates Please email the hotel directly quoting the booking code EES24 02 to confirm the exact price of the room Hotel AnlageISG Hotel Steffi s Hostel HeidelbergHotel Bayrischer Hof Hotel MonptiStaycity Aparthotel HeidelbergB B HotelMeininger HeidelbergHotel Vier Jahreszeiten HeidelbergHotel ibis HeidelbergPremier Inn Heidelberg City Travel information For travel information please see here If you are travelling to the conference within Germany then you are eligible for the Deutsche Bahn Event Ticket called the Veranstaltungsticket in German This will result in a lower ticket price if your travel distance to Heidelberg is more than 100 km You need to provide proof of your event attendance when purchasing the ticket For more information in English see here or in German see here You can book your ticket here Conference shuttle buses Conference shuttle buses are free of charge for participants and depart from designated bus stops near the hotels to EMBL and back mornings and evenings Here is the conference shuttle bus timetable The bus stops for this conference are Hotel Staycity Speyerer Str 7 Kurf rsten Anlage Opposite Main Train Station Hotel Premier Kurf rsten Anlage 23 Leonardo Hotel Heidelberg City Center Bergheimer Str 63 Neckarmuenzplatz Heidelberg Tourist Information Peterskirche Bus stop ISG Hotel Im Eichwald 19 View Conference shuttle bus stops and hotels in a larger map Please note that not every bus stop will be used for every event Further details Address EMBL Meyerhofstra e 1 69117 Heidelberg Germany For more information about accommodation and travel please refer to the FAQ page Onsite information Catering All meals and coffee breaks are included in the registration fee Our catering staff will prepare a wide variety of vegetarian meals meat and fish dishes soups pasta fresh fruit and vegetables as well as a variety of desserts Please wear your badge at all times when serving yourself No food or drinks are allowed in the auditorium Charging lockers There are lockers available next to the stairs leading down into the Auditorium You will find some of those equipped with sockets to charge your smartphone tablet etc Electricity and charging station In most places the electricity is 220 volts AC 50 cycles An adaptor and a plug that fits the German socket may be needed for your appliances laptop i e American Japanese etc A USB charging station for electronic devices is available at the registration desk EMBL merchandise If you are interested in purchasing EMBL merchandise products presented in the glass display in the registration area please email the EMBL shop to place an order or get in contact with your Course Organiser Kindly note the EMBL shop is only open upon request and all purchases must be made in cash Euros only Health and safety notes Please read EMBL s COVID 19 safety policy for on site events Do not smoke in any EMBL building Eating and drinking is prohibited in the Auditorium and all laboratories Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required The first aid room is located next to the ATC Registration Desk room 10 205 Dial the Emergency number 222 from any EMBL internal phone only Where is the accident What happened How many injured Emergency number 06221 387 7821 from mobile phones Please report all accidents to the conference officer at the registration desk In case of fire Press the nearest fire alarm button or the Emergency number 222 from any internal phone A loud fire alarm will go off if an evacuation is required On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting points Do not use the lifts Beyond first aid Please remember to bring your own medication if needed to the conference Note that the next pharmacy is a 4 minute drive from the EMBL but for many medications you will be required to see a doctor to get a prescription Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg In any case the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary Internet Wi Fi is available on campus using the EMBL Events network and the event specific password which will be provided on site The eduroam network secure worldwide roaming access service developed for the international research and education community is also available Lost and found Lost and Found items are kept at the registration desk until the end of the conference Luggage There are lockers available on site to store your luggage which require a 2 EURO coin to operate There is another luggage room on level E0 which is free to use but remains unlocked during the conference Nursing room There is a nursing room available in the ATC Rooftop Lounge on level A29 Photography During the conference an EMBL Photographer may be taking photos If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Printing We can help to print your boarding pass train ticket Please send it to events embl de and collect your print outs at the registration desk Room for prayer yoga and meditation There is a room for prayer meditation and yoga located on level E0 behind the Auditorium Please be respectful of others using the room Sightseeing A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing Travel to and from the venue During the event we provide conference shuttle buses to and from EMBL In addition there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time Information on the conference shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page Useful German expressions HelloHalloGoodbyeAuf Wiedersehen formal Tsch ss informal Good morningGuten MorgenGood afternoonGuten TagGood eveningGuten AbendGood nightGute NachtI m sorryEs tut mir leidExcuse me Entschuldigen SieHow are you Wie gehts I m fine thanks And you Mir geht es gut danke Und Dir Ihnen What is your nameWie hei en Sie formal Wie hei t du informal My name is Ich hei e Do you speak EnglishSprechen Sie englisch I don t understandIch verstehe nichtPlease speak more slowlyK nnen Sie bitte langsamer sprechenThank youDankesch nWhere is the toilet Wo ist die Toilette Please call me a taxiBitte rufen Sie mir ein TaxiHow do I get to Wie komme ich zum zur A beer two beers pleaseEin Bier zwei Bier bitteA glass of red white wine pleaseEin Glas Rot Wei wein bitteThe menu pleaseDie Speisekarte bitteIs there a local speciality Gibt es eine Spezialit t aus dieser Gegend I m vegetarianIch bin VegetarierIt was deliciousEs war hervorragendThe bill pleaseDie Rechnung bitteI have a headacheIch habe KopfschmerzenI have a sore throatIch habe HalsschmerzenMy stomach hurtsIch habe MagenschmerzenI m allergic toIch bin allergisch gegenI need a doctor who speaks English Ich brauche einen Arzt der englisch spricht Virtual participation What s included Access to all the livestreamed talks Video library of the recorded talks during the event and for two weeks afterwards Please note at the request of individual speakers some talks are not recorded Facility to submit questions Please note that only on site participants are able to submit abstracts and participate in the poster sessions Event platform We are using an event platform for this conference More information about the platform will be shared ahead of the conference Guidelines Do not broadcast the conference to unregistered participants You are encouraged to tweet and post about the event Tweet unless the speaker specifically says otherwise but be mindful of unpublished data Please do not capture transmit or redistribute data presented at the meeting Additional information can be found in our Code of Conduct Health and well being It is important to stay healthy and move around especially when you are attending an event virtually We have put together a few coffee break stretches and yoga videos in the conference platform for you to enjoy during the event How to ask questions Please use the Q A function in the event platform If you have any other questions you can go to the Help Desk in the event platform Click on more on the top menu and click Help Desk Time zone The programme is planned based on the Europe Berlin time zone unless otherwise stated Please take your time zone into consideration when planning your attendance Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for participants page COVID 19 related questions COVID 19 information for onsite events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Event sponsor Bruker goodBot Event supporter Media partners EMBO Reports an EMBO Press journal FEBS Letters International Union of Biochemistry and Molecular Biology Medinformatics a Bon View Publishing journal Open Biology a Royal Society journal Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de About EMBO EMBL Symposia promote scientific communication and collaboration in the European research area They provide scientists with a platform to discuss and exchange ideas on forward looking topics and new developments in the life sciences Topics emphasise upcoming developments and the interdisciplinary nature of related fields Jointly funded and organised by EMBO and EMBL and complementary to their respective courses workshops and conference programmes the symposia promote scientific communication and collaboration All symposia are held in the EMBL Advanced Training Centre ATC in Heidelberg Germany or virtually Media Kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9 Leaderboard 728 90...

Alexander Aulehla, Alan Hastings, Hanspeter Herzel, Carrie Partch

EMBO | EMBL Symposium

EMBL Heidelberg, Virtual

19 March - 22 March 2024

Protein quality control for downstream processes

Edit

March 19, 2024 00:002024CourseEMBL Heidelberg

Description OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview Course overview Purified proteins are used in various types of scientific experiments and fields For example in structural biology insights into the functional mechanisms can be obtained by elucidating the 3D molecular structure of proteins and protein complexes using technologies such as X ray crystallography cryo EM and NMR In biochemistry and biophysics interactions with other proteins nucleic acids and small molecules can be studied by determining affinities and specificities Proteins can function as antigens to generate specific antibodies or as reagents in cell biology experiments Furthermore recombinant proteins can be used as tool molecules in genomics chemical biology and microscopy assays In order for these experiments to produce reliable and biologically relevant results they must be performed using high quality proteins that are active properly folded in the right oligomeric state and contain correctly inserted co factors Ensuring that these parameters are fulfilled requires quality control In this course we want to help the participants to become acquainted with the concept of protein quality control and provide them with an overview of the specific protein requirements for various downstream applications Different techniques that can be applied for this purpose will be introduced and participants will have the opportunity to get hands on experience with these technologies Audience This course is aimed at life science researchers of all levels who are using or plan to use purified proteins in their wet lab experiments but who do not necessarily have a strong background in protein production and characterisation methods We will focus on introducing protein quality control methodologies in order to improve the reliability and reproducibility of data obtained from experiments that make use of purified proteins After this course participants should be familiar with the biochemical and biophysical techniques that can be applied to ensure that they are working with high quality protein samples suitable for the planned downstream experiments Modules resources Basic information Protein expression and purification process Protein concentration Buffer conditions pH ionic strength buffer components Purity and intactness SDS PAGE right size no degradation UV VIS spectrum nucleic acid contaminations Mass spectrometry expected molecular weight and amino acid sequence Homogeneity polydispersity SEC SEC MALS oligomeric state no aggregates molar mass DLS presence of aggregates Mass photometry oligomeric state molar mass Flow Induced Dispersion Analysis presence of aggregates Folding state and conformational stability Circular dichroism secondary structure influence of buffer conditions and or ligands Nano DSF thermofluor optimal buffer conditions thermal stability Activity Enzymatic assays functionality Interaction studies ITC MST Flow Induced Dispersion Analysis affinity for binding partners Learning outcomes During the course specialists from both academia and industry will work closely together to introduce technologies frequently used in protein quality control Some of these methodologies can be utilised both to assess protein quality and as standalone biophysical characterisation techniques Our main goals are Teach the participants how to perform proper protein quality control checks Introduce the participants to various biophysical techniques used for protein characterization such as SEC MALS DLS SLS mass photometry nano DSF flow induced dispersion analysis and spectroscopy Show participants how to characterize protein interactions using ITC MST and flow induced dispersion analysis Where possible allow participants to apply these technologies onto their own protein samples in the practicals Overall increase the success rate reliability and reproducibility of downstream experiments in which purified proteins are used What past participants say about the course This advanced course was my first live experience at the EMBL and it was superb It was packed with great lectures state of the art technology fruitful discussions and beautiful people The course was also a great opportunity to meet new people and expand your network Highly recommend and I will definitely attend the next event Klemen Mezgec National Institute of Chemistry Ljubljana Slovenia Speakers Speakers trainers and staff Sebastian Eustermann EMBL Heidelberg Germany David Golonka Wyatt Technology Germany Felix Gloge Wyatt Technology Germany Janosch Hennig EMBL and University of Bayreuth Germany Marijke Jansma NanoTemper Technologies Germany Sebastian Joecks Refeyn UK Stephan Koetzner FidaBio Denmark Arpita Kundu NanoTemper Technologies Germany Karine Lapouge EMBL Heidelberg Germany Caroline Mas Biophysics Platform Insitut de Biologie Structurale Grenoble France Melanie McDowell Max Planck Institute of Biophysics Germany Stephen Maughan Refeyn UK Bertrand Raynal Institut Pasteur France Kim Remans EMBL Heidelberg Germany Mandy Rettel EMBL Heidelberg Germany Agatha Rosenthal Malvern Pananalytical UK Jan Schaeferkordt Refeyn UK Sascha Schifrin Wyatt Technology Germany Arthur Sedivy Protein Technologies Core Facility Vienna BioCenter Austria Peter Spies FidaBio Denmark Bernd Tartsch Malvern Pananalytical UK Scientific organisers Karine Lapouge EMBL Heidelberg Germany Kim Remans EMBL Heidelberg Germany Bertrand Raynal Institut Pasteur France Course organisers Maria Bacadare Course and Conference Team Lead EMBL Heidelberg Germany Swetlana Krez Scientific Training Officer EMBL Heidelberg Germany Programme Are you on social media Post using EMBLProteinQC and don t forget to tag EMBLEvents Day 1 Tuesday 19 March 2024 Time Europe Berlin SpeakerLocation08 20 08 50Bus from Premier Inn Hotel to EMBLPremier Inn City Center Hotel bus stop09 00 09 45Welcome house notes course overviewKarine Lapouge EMBL Heidelberg GermanyKim Remans EMBL Heidelberg GermanyCourtyard Room A B09 45 10 00Tour de tableCourtyard Room A B10 00 11 00Flash talks 20 students 3 minutes eachCourtyard Room A B11 00 11 30Coffee breakCourtyard Room A B11 30 11 50FidaBio introductionStephan Koetzner FidaBio DenmarkPeter Spies FidaBio DenmarkCourtyard Room A B11 50 12 10Malvern introductionAgatha Rosenthal Malvern Pananalytical UKBernd Tartsch Malvern Pananalytical UKCourtyard Room A B12 10 12 30NanoTemper introductionMarijke Jansma NanoTemper Technologies GermanyArpita Kundu NanoTemper Technologies GermanyCourtyard Room A B12 30 13 30LunchEMBL Canteen13 30 13 50Refeyn introductionSebastian Joecks Refeyn UKJan Schaeferkordt Refeyn UKCourtyard Room A B13 50 14 10Wyatt introductionFelix Gloge Wyatt Technology GermanyDavid Golonka Wyatt Technology GermanySascha Schifrin Wyatt Technology GermanyCourtyard Room A B14 10 15 00Lecture 1 Assessing and improving protein sample qualityBetrand Raynal Institut Pasteur FranceCourtyard Room A B15 00 15 30Coffee breakCourtyard Room A B15 30 18 30Practical session 1All trainersTraining Lab A B18 30 20 00DinnerATC Rooftop Lounge20 00 20 30Bus from EMBL to Premier Inn HotelEMBL bus stop Day 2 Wednesday 20 March 2024 Time Europe Berlin SpeakerLocation08 20 08 50Bus from Premier Inn Hotel to EMBLPremier Inn City Center Hotel bus stop09 00 09 10Overview of the dayCourtyard Room A B09 10 10 00Lecture 2 An overview of protein expression and purification methods for obtaining high quality protein samplesKim Remans EMBL Heidelberg GermanyCourtyard Room A B10 00 10 30Coffee breakCourtyard Room A B10 30 11 20Lecture 3 Spectroscopy Methods for Protein Quality ControlArthur Sedivy Protein Technologies Core Facility Vienna BioCenter AustriaCourtyard Room A B11 20 12 10Lecture 4 Analytical Ultracentrifugation for samples characterization and quality controlCaroline Mas Biophysics Platform Insitut de Biologie Structurale Grenoble FranceCourtyard Room A B12 10 13 10LunchEMBL Canteen13 10 16 30Practical session 2All trainersTraining Lab A B16 30 17 00Coffee breakCourtyard Room A B17 00 17 50Preparation time for group presentationsCourtyard Room A B17 50 18 45Tour Protein Expression and Purification Core Facility PEPCF PEPCF EMBL18 45 19 15Bus departure to downtownEMBL bus stop19 30 00 00Downtown dinner Day 3 Thursday 21 March 2024 Time Europe Berlin SpeakerLocation08 20 08 50Bus from Premier Inn Hotel to EMBLPremier Inn City Center Hotel bus stop09 00 09 10Overview of the dayCourtyard Room A B09 10 12 10Practical session 3All trainersTraining Lab A B12 10 13 15LunchEMBL Canteen13 15 14 05Lecture 5 Protein quality control and cryoEM for membrane proteinsMelanie McDowell Max Planck Institute of Biophysics GermanyCourtyard Room A B14 05 15 00Lecture 6 Mass spectroscopy methods used in protein characterisation and quality controlMandy Rettel EMBL Heidelberg GermanyCourtyard Room A B15 00 15 30Coffee breakCourtyard Room A B15 30 18 30Practical session 4All trainersTraining Lab A B18 30 20 00DinnerCourtyard Room A B20 00 20 30Bus from EMBL to Premier Inn HotelEMBL bus stop Day 4 Friday 22 March 2024 Time Europe Berlin SpeakerLocation08 20 08 50Bus from Premier Inn Hotel to EMBLPremier Inn City Center Hotel bus stop09 00 09 10Overview of the dayCourtyard Room A B9 10 10 00Lecture 7 Cryo EMSebastian Eustermann EMBL Heidelberg GermanyCourtyard Room A B10 00 10 50Lecture 8 NMR as a tool for protein quality controlJanosch Hennig EMBL Heidelberg University of Bayreuth GermanyCourtyard Room A B10 50 11 15Coffee breakCourtyard Room A B11 15 12 15Discussion practical 1Courtyard Room A B12 15 13 15LunchEMBL Canteen13 15 14 15Discussion practical 2Courtyard Room A B14 15 15 15Discussion practical 3Courtyard Room A B15 15 16 15Discussion practical 4Courtyard Room A B16 15 16 30Feed back and closing remarksCourtyard Room A B Practical information Registration fees and motivation letter The course is limited to 20 participants For selection purposes please note that your application will not be considered without a letter of motivation Registration Registration fees include admission course materials meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Academia 715PhD Student 715Industry 1225 A letter to support your visa application will be issued on request once payment of the registration fee is confirmed We recommend that you book your visa appointment as soon as possible to avoid any delay with your visa application Confirmation and payment The registration fee should be paid only after acceptance to the course The results will be announced approximately 2 3 weeks after the application deadline Motivation letter submission After you have logged in and successfully registered you will receive an email asking you to submit your motivation letter Click on the link provided and enter your motivation letter in the text box provided Alternatively you can submit your motivation letter by clicking on the link on the confirmation page directly after registering Instructions Include your relevant skills experience and qualifications showing why you would be suitable for the course Explain why you would like to attend including what you can contribute and how you think you will benefit from the course Please note The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised For detailed instructions please watch our video on how to submit a course motivation letter Further details For further information about registration and motivation letter submission please refer to the FAQ page Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of registration fee waivers travel grants and childcare grants Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course Travel grant The travel grant will cover the cost of travel airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Course within Europe up to 1000 for participants travelling to an EMBL Course from outside Europe up to 500 for any participant travelling to an EMBO Practical Course up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Practical Course up to 700 for any participant working in Croatia Czech Republic Estonia Greece Hungary Italy Lithuania Luxembourg Poland Slovenia and Turkey travelling to an EMBO Practical Course Registration fees are only covered for EMBO Practical Courses The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant There is the possibility to apply for a childcare grant to offset child care costs incurred by participants speakers trainers and organisers when attending a course Eligible costs include but are not limited to fees for a babysitter or child care facility and travel costs for a caregiver Please note that priority will be given to early stage researchers There is a limited amount of funding available for the childcare grants and funds will be distributed amongst eligible applicants Boehringer Ingelheim Fonds travel grant Applies to selected courses only Availability will be indicated during the motivation letter submission process This grant covers costs related to your attendance at the course registration travel and accommodation costs The grant is restricted to PhD students and postdocs who conduct basic biomedical research Whether you are eligible to apply for a travel grant depends on when you received your university entrance qualification e g Abitur A Levels High School Diploma Final State Examination for PhD and MD students as well as graduates the university entrance qualification must not have been obtained more than 11 years ago at the time of the envisaged course for postdocs the university entrance qualification must not have been obtained more than 13 years ago at the time of the envisaged course Application You may apply for financial assistance when submitting your motivation letter for courses In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application For the Boehringer Ingelheim Fonds Travel Grant there is a pre application question during the motivation letter submission process and if selected you will be requested to complete a standard form and documentation consisting of your travel expense estimation Selection The scientific organisers will select the recipients of all financial assistance during the motivation letter selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the course Selection is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details See our list of external funding opportunities and for further information about financial assistance please refer to the FAQ page Accommodation and travel Travel information For travel information please see here If you are travelling to the conference within Germany then you are eligible for the Deutsche Bahn Event Ticket called the Veranstaltungsticket in German This will result in a lower ticket price if your travel distance to Heidelberg is more than 100 km You need to provide proof of your event attendance when purchasing the ticket For more information in English see here or in German see here You can book your ticket here Hotel Accommodation is not included in the registration fee Participants are expected to book and pay for their own accommodation A mix of single and twin rooms have been reserved for 4 nights 19 22 March 2024 at the Premier Inn Hotel City Centre Heidelberg Single rooms are limited and will be available on a first come first served basis After the selection process selected participants should contact the hotel directly to make a booking with a booking code code of your course e g PQC24 01 by the deadline of 20 February 2024 We recommend that all course participants stay in the dedicated hotel for the course Local transport Shuttle buses will go from the Hotel to EMBL and back mornings and evenings A bus schedule and location of the bus stops will be made available prior to the meeting Further details Address EMBL Heidelberg Meyerhofstra e 1 69117 Heidelberg GermanyFor more information about accommodation and travel please refer to the FAQ page On site information Travel information For travel information please see here If you are travelling to the conference within Germany then you are eligible for the Deutsche Bahn Event Ticket called the Veranstaltungsticket in German This will result in a lower ticket price if your travel distance to Heidelberg is more than 100 km You need to provide proof of your event attendance when purchasing the ticket For more information in English see here or in German see here You can book your ticket here Catering All meals and coffee breaks are included in the registration fee Our catering staff will prepare a wide variety of vegetarian meals meat and fish dishes soups pasta fresh fruit and vegetables as well as a variety of desserts Please wear your badge at all times when serving yourself No food or drinks are allowed in the laboratories Electricity and charging station In most places the electricity is 220 volts AC 50 cycles An adaptor and a plug that fits the German socket may be needed for your appliances laptop i e American Japanese etc A USB charging station for electronic devices is available at the registration desk EMBL Merchandise If you are interested in purchasing EMBL merchandise products presented in the glass display in the registration area please email the EMBL shop to place an order or get in contact with your Course Organiser Kindly note the EMBL shop is only open upon request and all purchases must be made in cash Euros only Health and safety notes Please read EMBL s COVID 19 safety policy for on site events Do not smoke in any EMBL building Eating and drinking is prohibited in all laboratories Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required The first aid room is located next to the ATC Registration Desk room 10 205 Dial the Emergency number 222 from any EMBL internal phone only Where is the accident What happened How many injured Emergency number 06221 387 7821 from mobile phones Please report all accidents to the conference officer at the registration desk In case of fire Press the nearest fire alarm button or the Emergency number 222 from any internal phone A loud fire alarm will go off if an evacuation is required On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting points Do not use the lifts Beyond first aid Please remember to bring your own medication if needed to the conference Note that the next pharmacy is a 4 minute drive from the EMBL but for many medications you will be required to see a doctor to get a prescription Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg In any case the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary Internet Wi Fi is available on campus Log in using the EMBL Events network and the event specific password which will be provided on site The eduroam network secure worldwide roaming access service developed for the international research and education community is also available Lost and found Lost and Found items are kept at the registration desk until the end of the conference Luggage There are lockers available on site to store your luggage which require a 2 EURO coin to operate There is another luggage room on level E0 which is free to use but remains unlocked during the conference Nursing room There is a nursing room available in the ATC Rooftop Lounge on level A29 Photography During the conference an EMBL Photographer may be taking photos If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Printing We can help to print your boarding pass train ticket Please send it to events embl de and collect your print outs at the registration desk Room for prayer yoga and meditation There is a room for prayer meditation and yoga located on level E0 behind the Auditorium Please be respectful of others using the room Sightseeing A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing Travel to and from the venue During the event we provide conference shuttle buses to and from EMBL In addition there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time Information on the shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page Map to walk from ISG Hotel to EMBL Additional information Address EMBL Heidelberg Meyerhofstra e 1 69117 Heidelberg Germany ATC orientation map Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page Technical requirements and event software Event software The EMBL eCampus learning platform will be used to collaborate communicate and network with all of the course participants All participants will receive information on how to join shortly before the course We recommend using Chrome Safari or Mozilla Firefox browsers for eCampus Sponsors Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other events or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9...

Karine Lapouge, Kim Remans, Bertrand Raynal

EMBL Heidelberg

18 March - 22 March 2024

Livestock genomics

Edit

March 18, 2024 00:002024CourseVirtual

Description This hands on virtual course will introduce participants to methods and approaches for analysing genomic data from common livestock species including cattle pig chicken and sheep During the course participants will learn about the use of sequencing methods in the field of livestock genomics resequencing genomes locating variant data annotating genomes and carrying out GWAS approaches The course will also cover the use of public EMBL EBI resources such as Ensembl EVA and ENA to progress in your research as well as to submit and share your discoveries with the community and will present relevant use cases in the field The course will enable you to harness the wealth of publicly available farmed animal datasets held in EMBL EBI public archives and utilise our free services and tools to for example identify genetic variants associated with disease identify genetic markers associated with desirable breeding traits or use Ensembl Variant Effect Predictor VEP tool to predict the functional impact of genetic variants EMBL EBI is committed to support the livestock research community and industry to improve animal health and welfare increase productivity and reduce environmental impact Virtual courseParticipants will learn via a mix of pre recorded lectures live presentations and trainer led computational exercises Live sessions will be delivered using Zoom with additional support and asynchronous communication via Slack Pre recorded material may be provided before the course starts that participants will need to watch read or work through to gain the most out of the actual training event In the week before the course there will be a brief induction session Computational practicals will run on EMBL EBI s virtual training infrastructure meaning participants will not require access to a powerful computer or install complex software on their own machines Participants will need to be available during the course hours maximum 09 00 18 30 GMT each day of the course Trainers will be available to assist answer questions and provide further explanations during these times...

Sophie Spencer

Virtual

13 March 2024

Strain-resolved approaches for human microbiome studies

Edit

March 13, 2024 15:302024WebinarVirtual

Description In the last few years the human microbiome has received great attention by the community due to its fundamental role in health and disease Advancements in the field have also been possible due to technological improvements in shotgun metagenomics including the development and application of computational approaches This webinar will introduce metagenomics for characterisation of the human microbiome with focus on computational tools to achieve strain level resolution This will comprise pipelines for generation of profiles as well as extraction of draft genomes It will also present some recent analyses aiming at conducting large scale scenario investigations including the use of machine learning approaches and the integration of human microbiomes with other sources You may either watch the entire presentation from the introduction or navigate directly to a specific section by clicking the links provided below IntroductionHow can we study the microbiome The shotgun metagenomics workflowMicrobiome and colorectal cancer CRC Strain resolved metagenomicsToward full mappability of the human microbiomeThe curated Food Metagenomic Data resourceQ A...

Virtual

12 March - 15 March 2024

AI and biology

Edit

March 12, 2024 00:002024ConferenceEMBL Heidelberg, Virtual

Description OverviewSpeakersProgrammePractical informationSponsorsAboutMedia kitDB train strike information Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Symposium overview Artificial intelligence AI is transforming virtually all areas of science and the life sciences are no exception AI based methods are pushing the limits of what is possible in experimental design data analysis simulation and modelling The aim of this symposium is to catalyse synergistic interactions between AI researchers in different subfields of biology by exploring shared theoretical approaches cross domain experiments and data integration as well as shared topics in dissemination of tools and collaboration with experimental labs Furthermore we will look into the future and discuss how the concerted actions of AI and life science communities can enable both fields to exploit the full potential of the ongoing data deluge and find new application areas ripe for disruption by AI AI based analytics is subject to active research in at least three major application areas sequencing imaging and structural biology While all three domains are experiencing very fast growth the development of AI based analysis is largely happening independently The aim of our symposium is to bring these communities together to discuss topics of mutual interest to make progress including on the theoretical methodological side and on the more strategic issues of identifying the next areas of high potential Session topics Challenging the state of the art Cross domain cross modality learning Explainable AI and its role in science From algorithms to biology Connections to the wider AI field Generative modeling from drug design to synthetic images Speakers Mohammed AlQuraishi Columbia University USA Ewan Birney EMBL EBI Hinxton UK Michael Bronstein University of Oxford UK Arne Elofsson SciLifeLab Sweden Trey Ideker University of California San diego USA Florian Jug Human Technopole Italy Samuel Kaski Aalto University and University of Helsinki Finland Jennifer Listgarten University of California Berkeley USA Julia Mahamid EMBL Heidelberg Germany Lena Meier Hein German Cancer Research Center Germany Alex Rives New York University USA Fabian Theis Helmholtz Munich Germany Caroline Uhler Broad Institute of MIT and Harvard USA Mihaela van der Schaar University of Cambridge UK Jong Chul Ye Korea Advanced Institute of Science and Technology KAIST Korea Ellen Zhong Princeton University USA Scientific organisers Mohammed AlQuraishi Columbia University USA Wolfgang Huber EMBL Heidelberg Germany Anna Kreshuk EMBL Heidelberg Germany Emma Lundberg Stanford University USA Oliver Stegle EMBL Heidelberg and German Cancer Research Center Conference organiser Charlotte Courtney EMBL Heidelberg Germany Programme Are you on social media Post using EESAIBio and don t forget to tag EMBLEvents Please note that the programme is subject to change Some speakers may need to join virtually to give their talk For registered participants recorded talks will be accessible on demand for 2 weeks after the end of the event unless indicated otherwise Day 1 Tuesday 12 March 2024 Timings Europe CET Speaker12 00 13 30Registration and light refreshments13 45 17 15Session 1 Challenging the state of the artChairs Anna Kreshuk and Mohammed AlQuraishi13 30 13 45Opening remarks13 45 14 15Question everything A critical reflection of medical imaging AILena Maier Hein German Cancer Research Center Germany14 15 14 30GROVER Building a language model of the human genomeMelissa Sanabria Dresden University of Technology Germany14 30 14 45Deep mutational scanning of entire human protein interaction domain familiesGuillaume Diss Virtual speaker Friedrich Miescher Institute for Biomedical Research Germany14 45 15 15Coffee break and meet the speakers of day one Lena Maier Hein Michael Bronstein Mihaela van der Schaar15 15 15 45To be presented on siteMichael Bronstein University of Oxford UK15 45 16 00Protein engineering using transformer based energy landscape approximationEvgenii Lobzaev University of Edinburgh UK16 00 16 15AI based biomarker identification and profiling in heterogeneous prostate tumorsKathleen Marchal Ghent University IMEC Belgium16 15 16 45Beyond Causality Discovering and Analyzing the Governing Equations of MedicineMihaela van der Schaar University of Cambridge UK16 45 17 15Flash talks for poster session 1 Anna Poetsch 41 Bernard Ciraulo 55 Ava Khamseh 87 Christian Kolter 93 Dan Liu 103 Niklas Schmacke 143 Ron Schwessinger 145 Konstantina Tzavella 157 17 15 18 45Poster session 1 odd numbers 18 45 20 15Dinner in canteen20 15 22 00After dinner drinks in the ATC Foyer20 15Conference shuttle bus to all stops downtown including ISG21 00Conference shuttle bus to all stops downtown including ISG22 00Conference shuttle bus to all stops downtown including ISG Day 2 Wednesday 13 March 2024 Timings Europe CET Speaker08 45 9 00Arrival and coffee09 00 12 00Session 2 cross domain cross modality learningChairs Jong Chul Ye and Uwe Ohler09 00 09 30Learning a foundational representation of the cellular nicheFabian Theis Helmholtz Munich Germany09 30 09 45SpaceTree Deciphering Tumor Microenvironments by joint modeling of cell states and genotype phenotype relationships in spatial omics dataOlga Lazareva EMBL DKFZ Germany09 45 10 00Accurately predicting single cell drug responses of progressed melanoma patientsGabriele Gut University Hospital Z rich Switzerland10 00 10 30Coffee break and meet the EditorsGemma K Alderton Deputy Editor Insights ScienceGeorge Caputa Senior Editor Nature ResearchRituparna Chakrabarti Senior Scientific Editor iScienceQian Cheng Associate Editor Computational Biology Nature CommunicationsMike Fletcher Senior Editor Nature GeneticsSara Osman Associate Editor Nature Structural Molecular BiologyMaria Polychronidou Senior Editor Molecular Systems BiologyArunima Singh Senior Editor Nature Methods10 30 11 00Machine learning for reconstructing protein structure and dynamics from cryo EM imagesEllen Zhong Princeton University USA11 00 11 15AI based protein stability prediction from sequences and structures and its application to the engineering of plastic degrading enzymesAnia Di Pede Mattatelli Institute of Marine Sciences ICM CSIC Barcelona Spain11 15 11 30Regression on latent spaces predicts multi condition single cell gene expressionConstantin Ahlmann Eltze EMBL Heidelberg Germany11 30 12 00To be presented on siteSami Kaski Aalto University and University of Helsinki Finland12 00 13 30Lunch13 30 16 00Session 3 Explainable AI and its role in scienceChairs Leopold Parts and Alex Rives13 30 14 00Causal Representation Learning and Optimal Design of InterventionsCaroline Uhler Broad Institute of MIT and Harvard USA14 00 14 15Learning and visualizing the morphological differences between synapses of different typesDiane Adjavon HHMI Janelia USA14 15 14 30MoCHI mechanistic AI models from deep mutational scanning dataAndre Faure ALLOX Spain14 30 15 00Coffee break and meet the speakers of day two Fabian Theis Ellen Zhong Sami Kaski Caroline Uhler Trey Ideker15 00 15 30Assembling a Digital Tumor CellTrey Ideker University of California San Diego USA15 30 15 45Variational autoencoder for design of synthetic viral vector serotypesMichael Garton Virtual speaker University of Toronto Canada15 45 16 00Comprehensive characterization of human druggable pockets through novel binding site descriptors built upon inverse dockingArnau Comajuncosa Creus IRB Barcelona Spain16 00 Free evening downtown Heidelberg16 15Conference shuttle bus to all stops downtown including ISG Day 3 Thursday 14 March 2024 Timings Europe CET Speaker08 45 09 00Arrival and coffee09 00 12 15Session 4 from algorithms to biologyChairs Ellen Zhong and Florian Jug09 00 09 30The convergence of genomics imaging and AI for understanding lifeEwan Birney EMBL EBI Hinxton Cambridge UK09 30 09 45Modeling regulatory networks with single cell expression dataUwe Ohler Max Delbr ck Center for Molecular Medicine and Humboldt University of Berlin Germany09 45 10 00Pre trained molecular representations can aid antimicrobial discoveryRoberto Olayo Institute for Statistics LMU M nchen Germany10 00 10 30Coffee break 10 30 11 00Enabling discovery by in cell structural biology challenges in cryo electron tomography data mining and integrationJulia Mahamid EMBL Heidelberg GermanyNot available on demand11 00 11 15Integration of variant annotations using deep set networks boosts rare variant association geneticsEva Holtkamp Technical University of Munich Germany11 15 11 30Exploiting time to phenotype cell morphologyJulian Pietsch Max Planck Institute for Terrestrial Microbiology Germany11 30 12 15Panel discussion From algorithms to biologyModerator Emma Lundberg12 15 13 45Lunch13 45 16 45Session 5 connections to the wider AI fieldChairs Oliver Stegle and Samuel Kaski13 45 14 15Towards a Complete Structural Map of the Human Proteome Using AlphaFoldArne Elofsson SciLifeLab Sweden14 15 14 30Towards transformer based tracking in live cell microscopyBenjamin Galusser EPFL Switzerland14 30 14 45Can AI predict how human cells interpret dinosaur DNA Leopold Parts The Wellcome Trust Sanger Institute UK14 45 15 15Coffee break and meet the speakers of day three Ewan Birney Julia Mahamid Arne Elofsson Alex Rives Jong Chul Ye15 15 15 45Language Modeling at the Scale of EvolutionAlex Rives EvolutionaryScale USANot available on demand15 45 16 00BioCypher and BioChatter open frameworks for AI ready biomedical knowledge graphs and their integration with current Large Language ModelsSebastian Lobentanzer Heidelberg University and Heidelberg University Hospital Germany16 00 16 30Enlarging the Capability of Diffusion Models for Inverse Problems in ImagingJong Chul Ye Korea Advanced Institute of Science and Technology KAIST Korea16 30 16 45PeTriBERT Augmenting BERT with tridimensional encoding for inverse protein folding and designBaldwin Dumortier CNRS France16 45 17 15Flash talks for poster session 2 Cedric Allier 42 Noah Bruderer 52 Adele de Hoffer 58 Albert Dominguez Mantes 62 Lucas Farndale 64 Lucien Hinderling 76 Grzegorz Kudla 96 Xiaomei Li 100 Paulyna Maga a 106 Abdelrahman Mahmoud 108 Roman Bushuiev 138 Yuxin Shen 148 17 15 18 45Poster session 2 even numbers 18 45 21 00Conference dinner21 00 00 00Party with The Chaotics band20 30Conference shuttle bus to all stops downtown including ISG21 30Conference shuttle bus to all stops downtown including ISG22 30Conference shuttle bus to all stops downtown including ISG23 59Conference shuttle bus to all stops downtown including ISG Day 4 Friday 15 March 2024 Timings Europe CET Speaker08 45 09 00Arrival and coffee09 00 13 00Session 6 generative modeling from drug design to synthetic imagesChairs Wolfgang Huber and Arne Eloffson09 00 09 30From Content Aware Denoising to Semantic Unmixing of Microscopy Data how AI is and will transform scientific image data analysis in the life sciencesFlorian Jug Human Technopole Italy09 30 09 45Controllable generative modelling lessons from protein designKieran Didi University of Cambridge UK09 45 10 15Some thoughts on machine learning based protein engineeringJennifer Listgarten University of California Berkeley USA10 15 10 45Coffee Break and Meet the speakers of day four Florian Jug Jennifer Listgarten Mohammed AlQuraishi10 45 11 45Panel discussion Industry vs AcademiaModerators Wolfgang Huber and Oliver Stegle11 45 12 00Seedling a scoring and generation framework for protein ligand co foldingWilliam McCorkindale Charm Therapeutics UK12 00 12 30To be presented on siteMohammed AlQuraishi Columbia University USA12 30 12 45Efficient and accurate sequence generation with small scale protein language modelsYaiza Serrano Nostrum Biodiscovery Spain12 45 13 00Closing Remarks and Poster Prize Announcements13 00Packed lunch and departure13 20Conference shuttle bus to all stops downtown including ISG13 20Conference shuttle bus to Frankfurt Am Main International Airport Practical information Registration fees and abstract submission On site registration fees include admission conference materials meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Virtual registration fees include access to all of the talks live streamed and on demand and the facility to submit questions On site Academia 725On site PhD Student 625On site Industry 925On site Journal Editors 300Virtual Academia 225Virtual PhD Student 175Virtual Industry 275 Editors from scientific journals are allowed to attend at a reduced rate but asked to contribute to the conference in return by taking part in meet the editors sessions or other planned activities within the programme A letter to support your visa application will be issued on request once payment of the registration fee is confirmed We recommend that you book your visa appointment as soon as possible to avoid any delay with your visa application Accredited journalists may be eligible to register for complimentary press registration Registrants may be required to provide accreditation or equivalent proof of press membership after registration Please contact Charlotte Courtney for more information Please note that we do not offer complimentary registrations for editors of scientific journals Confirmation and payment Registration will be on a first come first served basis Your place can only be confirmed after payment of the registration fee If you are added to our waiting list please consider taking advantage of our offerings to participate virtually On site participants Types of payments accepted are international bank transfers and credit card payments Virtual participants We are only able to accept card payments In exceptional cases we can accept bank transfers Please contact events embl de for details Abstract submission Only participants registering to attend the on site event are eligible to submit an abstract Abstracts will not be accepted from virtual participants After registration you can submit your abstract via a separate link that will be provided in the email confirmation Alternatively you can access the link on the confirmation page directly after registering The same login credentials are used for both processes Please note Abstract body The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised Title The title should not exceed 20 words Only the first word of the title should start with a capital letter and the rest should be lowercase Authors and affiliations Please fill in the author s details as requested in the online form The compulsory fields are First Name Last Name Organisation Name Affiliation or Company Country and Email Kindly mark only one author in the role of First Author and please don t forget to indicate who will be the Presenter Please enter your co authors correctly via the system by adding accounts together with their organisation institute Do not copy paste them into the body of the abstract text as they will not be indexed in the abstract book Presentation types When submitting your abstract you can apply for an oral or poster presentation A selection process will take place with the results announced 2 3 weeks after the abstract submission deadline For detailed instructions on how to submit a conference abstract follow the instructions provided in this video Please check our FAQs pages for further information on how to submit an abstract Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of registration fee waivers travel grants and childcare grants Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course or conference Travel grant The travel grant will cover the cost of travel to an on site event airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from within Europe up to 1000 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from outside Europe up to 500 for any participant travelling to an EMBO Workshop up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Workshop up to 700 for any participant working in Croatia Czech Republic Estonia Greece Hungary Italy Lithuania Luxembourg Poland Slovenia and Turkey travelling to an EMBO Workshop Registration fees are only covered for EMBO Workshops The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant There is the possibility to apply for a childcare grant to offset child care costs incurred by participants speakers and organisers when attending a conference Eligible costs include but are not limited to fees for a baby sitter or child care facility and travel costs for a caregiver Please note that priority will be given to early stage researchers In order to apply for this grant you must be registered by the abstract submission deadline There is a limited amount of funding available for the childcare grants and funds will be distributed amongst eligible applicants Application On site participants You may apply for financial assistance when submitting your abstract In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Virtual participants If you are attending virtually you can apply for financial assistance in the submission portal by the abstract deadline Read the instructions on how to apply for financial assistance Only submissions for financial assistance will be accepted Presentation abstracts cannot be submitted here and will be declined In your application you will be asked to summarise your current work answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Selection The scientific organisers will select the recipients of all financial assistance during the abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details View our list of external funding opportunities and information on attending a conference as an event reporter For further information about financial assistance please refer to the FAQ page Accommodation and travel Accommodation is not included in the conference registration fee The hotels below have rooms on hold for participants until Monday 12th February 2024 in some cases at special rates Please email the hotel directly quoting the booking code EES24 01 to confirm the exact price of the room Hotel AnlageHotel ibis HeidelbergPremier Inn Heidelberg CityHotel Bayrischer Hof ISG Hotel Staycity Aparthotel HeidelbergB B HotelLeonardo Hotel Heidelberg City CentreSteffi s Hostel HeidelbergExzellenz HotelMeininger HeidelbergHotel Vier Jahreszeiten HeidelbergHotel Holl nder Hof Hotel Monpti Travel information For travel information please see here If you are travelling to the conference within Germany then you are eligible for the Deutsche Bahn Event Ticket called the Veranstaltungsticket in German This will result in a lower ticket price if your travel distance to Heidelberg is more than 100 km You need to provide proof of your event attendance when purchasing the ticket For more information in English see here or in German see here You can book your ticket here Conference shuttle buses Conference shuttle buses are free of charge for participants and depart from designated bus stops near the hotels to EMBL and back mornings and evenings Here is the conference shuttle bus timetable The bus stops for this conference are Staycity Aparthotel Speyerer Str 7 Kurf rsten Anlage Opposite Main Train Station Premier Inn Kurf rsten Anlage 23 Leonardo Hotel Heidelberg City Center Bergheimer Str 63 Neckarm nzplatz Heidelberg Tourist Information Peterskirche Bus stop ISG Hotel Im Eichwald 19 View Conference shuttle bus stops and hotels in a larger map Please note that not every bus stop will be used for every event Further details Address EMBL Meyerhofstra e 1 69117 Heidelberg Germany For more information about accommodation and travel please refer to the FAQ page On site information Catering All meals and coffee breaks are included in the registration fee Our catering staff will prepare a wide variety of vegetarian meals meat and fish dishes soups pasta fresh fruit and vegetables as well as a variety of desserts Please wear your badge at all times when serving yourself No food or drinks are allowed in the auditorium Charging lockers There are lockers available next to the stairs leading down into the Auditorium You will find some of those equipped with sockets to charge your smartphone tablet etc Electricity and charging station In most places the electricity is 220 volts AC 50 cycles An adaptor and a plug that fits the German socket may be needed for your appliances laptop i e American Japanese etc A USB charging station for electronic devices is available at the registration desk EMBL merchandise If you are interested in purchasing EMBL merchandise products presented in the glass display in the registration area please email the EMBL shop to place an order or get in contact with your Course Organiser Kindly note the EMBL shop is only open upon request and all purchases must be made in cash Euros only Health and safety notes Do not smoke in any EMBL building Eating and drinking is prohibited in the Auditorium and all laboratories Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required The first aid room is located next to the ATC Registration Desk room 10 205 Dial the Emergency number 222 from any EMBL internal phone only Where is the accident What happened How many injured Emergency number 06221 387 7821 from mobile phones Please report all accidents to the conference officer at the registration desk In case of fire Press the nearest fire alarm button or the Emergency number 222 from any internal phone A loud fire alarm will go off if an evacuation is required On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting points Do not use the lifts Beyond first aid Please remember to bring your own medication if needed to the conference Note that the next pharmacy is a 4 minute drive from the EMBL but for many medications you will be required to see a doctor to get a prescription Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg In any case the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary Internet Wi Fi is available on campus using the EMBL Events network and the event specific password which will be provided on site The eduroam network secure worldwide roaming access service developed for the international research and education community is also available Lost and found Lost and Found items are kept at the registration desk until the end of the conference Luggage There are lockers available on site to store your luggage which require a 2 EURO coin to operate There is another luggage room on level E0 which is free to use but remains unlocked during the conference Nursing room There is a nursing room available in the ATC Rooftop Lounge on level A29 Photography During the conference an EMBL Photographer may be taking photos If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Printing We can help to print your boarding pass train ticket Please send it to events embl de and collect your print outs at the registration desk Room for prayer yoga and meditation There is a room for prayer meditation and yoga located on level E0 behind the Auditorium Please be respectful of others using the room Sightseeing A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing Travel to and from the venue During the event we provide conference shuttle buses to and from EMBL In addition there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time Information on the conference shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page Useful German expressions HelloHalloGoodbyeAuf Wiedersehen formal Tsch ss informal Good morningGuten MorgenGood afternoonGuten TagGood eveningGuten AbendGood nightGute NachtI m sorryEs tut mir leidExcuse me Entschuldigen SieHow are you Wie gehts I m fine thanks And you Mir geht es gut danke Und Dir Ihnen What is your nameWie hei en Sie formal Wie hei t du informal My name is Ich hei e Do you speak EnglishSprechen Sie englisch I don t understandIch verstehe nichtPlease speak more slowlyK nnen Sie bitte langsamer sprechenThank youDankesch nWhere is the toilet Wo ist die Toilette Please call me a taxiBitte rufen Sie mir ein TaxiHow do I get to Wie komme ich zum zur A beer two beers pleaseEin Bier zwei Bier bitteA glass of red white wine pleaseEin Glas Rot Wei wein bitteThe menu pleaseDie Speisekarte bitteIs there a local speciality Gibt es eine Spezialit t aus dieser Gegend I m vegetarianIch bin VegetarierIt was deliciousEs war hervorragendThe bill pleaseDie Rechnung bitteI have a headacheIch habe KopfschmerzenI have a sore throatIch habe HalsschmerzenMy stomach hurtsIch habe MagenschmerzenI m allergic toIch bin allergisch gegenI need a doctor who speaks English Ich brauche einen Arzt der englisch spricht Virtual participation What s included Access to all the livestreamed talks Video library of the recorded talks during the event and for two weeks afterwards Please note at the request of individual speakers some talks are not recorded Facility to submit questions Please note that only on site participants are able to submit abstracts and participate in the poster sessions Event platform We are using an event platform for this conference More information about the platform will be shared ahead of the conference Guidelines Do not broadcast the conference to unregistered participants You are encouraged to tweet and post about the event Tweet unless the speaker specifically says otherwise but be mindful of unpublished data Please do not capture transmit or redistribute data presented at the meeting Additional information can be found in our Code of Conduct Health and well being It is important to stay healthy and move around especially when you are attending an event virtually We have put together a few coffee break stretches and yoga videos in the conference platform for you to enjoy during the event How to ask questions Please use the Q A function in the event platform If you have any other questions you can go to the Help Desk in the event platform Click on more on the top menu and click Help Desk Time zone The programme is planned based on the Europe Berlin time zone unless otherwise stated Please take your time zone into consideration when planning your attendance Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for participants page COVID 19 related questions COVID 19 information for on site events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Bronze sponsor Event sponsor Novigenix Event supporters Media partners Disease Models Mechanisms The Company of Biologists Journal FEBS Letters International Union of Biochemistry and Molecular Biology Medinformatics a Bon View Publishing journal Molecular Systems Biology an EMBO Press Journal Open Biology a Royal Society journal PLOS Biology a PLOS journal Royal Society of Chemistry Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de About EMBO EMBL Symposia promote scientific communication and collaboration in the European research area They provide scientists with a platform to discuss and exchange ideas on forward looking topics and new developments in the life sciences Topics emphasise upcoming developments and the interdisciplinary nature of related fields Jointly funded and organised by EMBO and EMBL and complementary to their respective courses workshops and conference programmes the symposia promote scientific communication and collaboration All symposia are held in the EMBL Advanced Training Centre ATC in Heidelberg Germany or virtually Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 Leaderboard 728 90 DB train strike information Deutsche Bahn DB the national rail provider has announced a last minute strike affecting all rail travel across Germany on Tuesday 12 March Further details can be found here on the DB website There is a version in English here Currently DB state that long distance intercity trains regional and local trains will be severely disrupted DB rail tickets booked on or before 10 March for travel on Tuesday 12 March can now be used flexibly and are valid on any train either today Monday 11 March long distance trains only or after 12 March We realise this could impact your journey to the EMBO EMBL Symposium AI and biology The following information is to assist you in checking and adjusting travel plans to reach Heidelberg Arriving to Heidelberg Tuesday 12 March 2024 By train DB says that long distance regional and local S Bahn train services in Germany will be severely disrupted on Tuesday Only very few services will run The timetable will be updated regularly on the DB website and app If your accommodation arrangements can be changed consider making use of the flexible ticket validity announced by DB to travel to Heidelberg tonight before the strike Alternatively you could look into bus route alternatives driving or car sharing The strike affects only travel on the first day of the four day symposium Of course you will still be able to join if you arrive on day 2 as a last resort By air from Frankfurt Main Airport EMBL will provide 3 buses free of charge departing from Terminal 1 Bus stop P36 bus parking lot Frankfurt Main Airport at 9 00 1 bus and 11 30 2 buses Places are limited on a first come first served basis If you arrive before this time please wait at the airport until the buses depart These buses will take you directly to EMBL Heidelberg The buses Hoffman Reisen company will be on the P36 bus lot and have a sign displaying EMBL SHUTTLE in the front window By car car sharing Car parking is available at EMBL Heidelberg We recommend connecting with other participants in advance is the Discussion area in the virtual platform for the conference Joining instructions for the virtual conference platform have been sent to you separately Important Please check with your hotel if parking is available and if a reservation is required FAQS 1 Is the conference still running as scheduled YES 2 I cannot travel to EMBL Heidelberg to attend the conference onsite due to the strike and none of the above options work for me All is not lost as a second best you can attend the conference as a virtual participant using the details previously sent The strike only affects travel on the first day of the four day symposium 3 Can I get a refund if I cannot attend the conference Unfortunately not However you can still enjoy the conference as a virtual participant using the details previously sent 4 Will EMBL provide any other buses outside of what has been arranged during the strikes No However you can also make alternative transport arrangements by clicking on the useful links websites below 5 Do I need to reserve a seat on the EMBL airport bus on Tuesday 12 March No Seats are on a first come first served basis However we have planned that capacity will not be exceeded 6 Where do I find the buses at the Frankfurt airport From Terminal 1 you can reach the long distance bus parking lot P36 via Arrival C Then keep right The long distance bus parking lot is signposted 7 Does the strike affect local buses and trams in Heidelberg No Public buses and trams will continue to operate as planned 8 Do I need to pay for the EMBL buses from Frankfurt Main to Heidelberg on Tuesday 12 March No EMBL are providing this free of charge 9 How will I know which is the correct bus from the airport to Heidelberg EMBL on Tuesday 12 March At Frankfurt Main airport buses will depart from Terminal 1 Bus stop P36 parking lot Buses Hoffman Reisen company will have a sign displaying EMBL SHUTTLE in the front window of the bus 10 Will the conference shuttle buses from Heidelberg hotels to EMBL still run Yes we are providing transport service as usual at specific times Information can be found here 11 What if I miss the EMBL airport bus Alternative transport is available Please see useful websites below 12 Will the trains run on Friday check out day of the conference Yes The strike is expected to end at 2am on Wednesday 13 March We will keep participants updated if this changes You can also follow on the DB website here 13 Can I get a taxi from the airport to Heidelberg Yes official taxis which run on a meter basis are available outside the airports but this is an expensive option at around 200 Euros for a normal passenger car from Frankfurt airport for example Alternatively Personal Transfers Heidelberg are an option if you want to consider pre booking a private individual or group car transfer from the airport 14 Where can I connect with other participants to discuss transport arrangements An option for connecting with other participants in advance is the virtual platform for the conference under discussion menu Joining instructions for the virtual conference platform have been sent to you separately 15 If arriving directly to EMBL can I bring my luggage Yes There are lockers available on site to store your luggage which require a 2 EURO coin to operate There is another luggage room on level E0 which is free to use but remains unlocked during the conference Useful websites information DB Deutsche Bahn website containing useful strike and travel information TRN Airport Transfer airport transfer provider Taxi Weinmann taxi company close to Heidelberg offering airport transfers Flixbus bus transfers across Germany Busradar long distance buses EMBL information for participants travelling to EMBL Heidelberg Taxis from the airports official taxis which run on a meter basis are available outside the airports but this is an expensive option at around 200 Euros for a normal passenger car from Frankfurt airport for example We hope you find the above helpful However if you still have a question that is not answered above please email us with any queries at events embl de Please note Information is correct at the time of issue 11 March 2024 15 00 and is subject to change...

Mohammed AlQuraishi, Wolfgang Huber, Anna Kreshuk, Emma Lundberg, Oliver Stegle

EMBO | EMBL Symposium

EMBL Heidelberg, Virtual

11 March - 15 March 2024

Mathematics of life: modelling molecular mechanisms

Edit

March 11, 2024 00:002024CourseVirtual

Description This course will provide participants with an introduction and hands on training on modelling approaches tools and resources used in systems biology as well as touch on network analysis Computer models are increasingly used to understand the essential processes of biology Researchers in academic institutions as well as the pharmaceutical industry use mathematical models to generate hypotheses on how complex biomolecular systems work Modelling of biochemical pathways deregulated in disease conditions can offer mechanistic insights into the pathology help to elucidate mechanisms behind drug action and predict the dose required for treatment thus facilitating fundamental research and drug discovery This course will provide a helpful brief introduction to key modelling concepts and hands on training to use popular tools and resources used in this scientific field Virtual courseParticipants will learn via a mix of pre recorded lectures live presentations and trainer Q A sessions Practical experience will be developed through group activities and trainer led computational exercises Live sessions will be delivered using Zoom with additional support and asynchronous communication via Slack Pre recorded material may be provided before the course starts that participants will need to watch read or work through to gain the most out of the actual training event In the week before the course there will be a brief induction session Computational practicals will run on EMBL EBI s virtual training infrastructure meaning participants will not require access to a powerful computer or install complex software on their own machines Participants will need to be available between the hours of 09 00 17 30 GMT each day of the course Trainers will be available to assist answer questions and provide further explanations during these times...

Juanita Riveros

Virtual

6 March 2024

Bioinformatic approaches to understand the role of the human microbiome in health and disease

Edit

March 06, 2024 15:302024WebinarVirtual

Description The human microbiome represents a diverse community of microbes with important roles for the maintenance of human health The wealth of metagenomics data currently available has brought about a new era of research for the human microbiome field The ability to reconstruct high quality microbial genomes purely from metagenomic sequencing data has unlocked our ability to study the hidden microbial universe living alongside us Given there are thousands of human associated bacterial species that cannot yet be experimentally characterised there is a need to develop and apply bioinformatics methods to better understand their role in health and disease This webinar will provide an overview of current metagenomic approaches to study the human microbiome and introduce several statistical methods that can be used to link its composition and function to different human phenotypes and populations You may either watch the entire presentation from the introduction or navigate directly to a specific section by clicking the links provided below IntroductionThe microbiome in human biologyWhat can metagenomics tell us What is genome assembly Evaluating genome MAG qualityLinking microbiome composition to phenotypeAdditional resourcesQ A...

Virtual

4 March - 8 March 2024

Introduction to multi-omics data integration and visualisation

Edit

March 04, 2024 00:002024CourseEMBL-EBI

Meredith Willmott

EMBL-EBI

4 March - 8 March 2024

Gene expression at spatial resolution

Edit

March 04, 2024 00:002024CourseEMBL Heidelberg

Description OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview Course overview This interactive course will introduce participants to a new generation of a spatially resolved transcriptomics assay provided by 10x Genomics Objectives The Visium Cytassist Spatial Gene Expression Solution uses probes targeting the whole transcriptome for intact tissue sections in morphological context offering a previously inaccessible view of tissue biology These two complementary methods to study tissue come together on Visium Cytassist Spatial Gene Expression slides Through practical work in the lab and theoretical sessions the participants will learn the entire workflow of sample preparation of fresh frozen tissue samples fixation and sequencing library preparation Utilising the 10x Genomics Loupe Browser pipeline the participants will also have hands on training in spatial transcriptomics data analysis Audience This is an interdisciplinary course designed for molecular biologists as well as researchers more familiar with morphology analysis by brightfield and fluorescence microscopy who are seeking to introduce the 10x Genomics Visium Cytassist Spatial Gene Expression application into their labs research Modules Resources Overview of 10x Genomics Visium Cytassist Spatial Gene Expression technology Focusing on fresh frozen samples with Hematoxylin and Eosin H E staining Alternative staining by Immunofluorescence and usage of FFPE samples as starting material Pre recorded application lectures on Spatial Transcriptomics Theoretical aspects of cryosectioning and brightfield and fluorescence microscopy Visium Spatial Gene Expression data analysis using Loupe Browser license free 1 on 1 Project Consultation with application specialist optional service offered at the discretion of the individual participant Learning Outcomes After this course you will be able to Appreciate the importance of spatially resolved transcriptomics data Realise the significance of properly prepared tissue sections by cryosectioning Understand the requirements for brightfield and fluorescent tissue slide imaging Analyse and interpret data output using Loupe Browser What past participants say about the course Gene expression at spatial resolution workshop was amazing Thanks to the organizing team and all the trainers I could practice each step from sectioning to data analysis Also meeting with other participants with varying backgrounds and the expert lecturers was a great opportunity Mustafa Beter University of Eastern Finland Finland This course provided a week of hands on practical training on 10X Visium complemented by scientific talks and discussions Not only was I introduced to the workflow of the technique but I also received advice tailored to my specific research question and tissue type Rounded off with a thorough step by step guide on data analysis I now feel confident to start my experiments soon Lisa Mayrginther Maastricht University Finland Speakers Speakers trainers Ahmad Al Alwash EMBL Heidelberg Germany Monika Dabrowska 10x Genomics United Kingdom Linda Decker EMBL Heidelberg Germany Anna Klemm SciLifeLab and Uppsala University Sweden Mireia Osuna Lopez EMBL Heidelberg Germany Kristy Ou EMBL Heidelberg Germany Valeriy Pak EMBL Heidelberg Germany Idoia Quintana Urzainqui EMBL Heidelberg Germany Sinem Saka EMBL Heidelberg Germany Oliver Stegle EMBL Heidelberg Germany Laura Villacorta EMBL Heidelberg Germany Scientific organisers Vladimir Benes EMBL Heidelberg Germany Dirk J rgensen 10x Genomics Germany Elisabeth Zielonka EMBL Heidelberg Germany Course organisers Sophie Dutzi Course and Conference Officer EMBL Heidelberg Germany Irena Provaznikova Training Lab Technician EMBL Heidelberg Germany Programme Are you on social media Post using EMBLSpatialOmics and don t forget to tag EMBLEvents Some pre course work such as watching pre recordings protocol reading and computational exercises with estimated time 0 10 hours will be required and will be shared in advance of the course Some speakers may need to join virtually to give their lecture or Q A and the programme is subject to change Day 1 Monday 4 March 2024 Time Europe Berlin ProgrammeLocation08 40 09 00Bus from hotel to EMBL ATC EntranceBus stop in front of ISG Hotel08 45 09 00RegistrationCourtyard Room A B09 00 09 30Welcome and house notes and course overviewCourtyard Room A B09 30 10 30Flash talk sessionCourtyard Room A B10 30 11 00Coffee BreakCourtyard Room A B11 00 12 00Lecture 1 Introduction to the Visium Spatial Gene Expression WorkflowDirk J rgensen 10x Genomics GermanyCourtyard Room A B12 00 13 00LunchEMBL Canteen13 00 15 30Practical session 1 Sample fixation staining and probe hybridizationAhmad Al Alwash EMBL Heidelberg GermanyMonika Dabrowska 10x Genomics UKDirk J rgensen 10x Genomics GermanyFabio Marsoner 10x Genomics The NetherlandsMireia Osuna Lopez EMBL Heidelberg GermanyLaura Villacorta EMBL Heidelberg GermanyTraining Lab A B15 30 16 00Coffee breakCourtyard Room A B16 00 18 00CryoStat demo session ALMF tour and imagingMonika Dabrowska 10x Genomics UKAhmad Al Alwash EMBL Heidelberg GermanyLinda Decker EMBL Heidelberg GermanyDB unit ALMF18 00 19 00Lecture 2 Imaging good practicesAhmad Al Alwash EMBL Heidelberg GermanyCourtyard Room A B19 00 20 00DinnerEMBL Canteen20 00Departure to HotelATC Entrance Day 2 Tuesday 5 March 2024 Time Europe Berlin ProgrammeLocation08 40 09 00Bus from hotel to EMBL ATC EntranceBus stop in front of ISG Hotel09 00 09 05Overview of the dayTraining Lab B09 05 10 05Practical session 2 Post Hybridzation Wash Probe Ligation Ahmad Al Alwash EMBL Heidelberg GermanyMonika Dabrowska 10x Genomics UKDirk J rgensen 10x Genomics GermanyFabio Marsoner 10x Genomics The NetherlandsMireia Osuna Lopez EMBL Heidelberg GermanyLaura Villacorta EMBL Heidelberg GermanyTraining Lab B10 05 11 05Lecture 3 A DNA toolbox for spatial biologySinem Saka EMBL Heidelberg GermanyCourtyard Room A B11 05 12 05Practical session 3 Post ligation wash Ahmad Al Alwash EMBL Heidelberg GermanyMonika Dabrowska 10x Genomics UKDirk J rgensen 10x Genomics GermanyFabio Marsoner 10x Genomics The NetherlandsMireia Osuna Lopez EMBL Heidelberg GermanyLaura Villacorta EMBL Heidelberg GermanyTraining Lab B12 05 13 05LunchEMBL Canteen13 05 17 05Practical session 4 Cytassist sessionTraining Lab B17 05 17 35Practical session 5 Probe extension Ahmad Al Alwash EMBL Heidelberg GermanyMonika Dabrowska 10x Genomics UKDirk J rgensen 10x Genomics GermanyFabio Marsoner 10x Genomics The NetherlandsMireia Osuna Lopez EMBL Heidelberg GermanyLaura Villacorta EMBL Heidelberg GermanyTraining lab B17 35 18 35Lecture 4 Rubbish In Equals Rubbish Out The Importance of Sample QualityMonika Dabrowska 10x Genomics UKCourtyard Room A B18 35 19 35DinnerEMBL Canteen19 35Departure to HotelATC Entrance Day 3 Wednesday 6 March 2024 Time Europe Berlin ProgrammeLocation08 40 09 00Bus from hotel to EMBL ATC EntranceBus stop in front of ISG Hotel09 00 09 05Overview of the dayTraining lab B09 05 10 35Practical session 6 Probe elution and pre amplification Ahmad Al Alwash EMBL Heidelberg GermanyMonika Dabrowska 10x Genomics UKDirk J rgensen 10x Genomics GermanyFabio Marsoner 10x Genomics The NetherlandsMireia Osuna Lopez EMBL Heidelberg GermanyLaura Villacorta EMBL Heidelberg GermanyTraining lab B10 35 10 50Coffee breakCourtyard Room A B10 50 11 50Practical session 7 SPRI beads clean up Ahmad Al Alwash EMBL Heidelberg GermanyMonika Dabrowska 10x Genomics UKDirk J rgensen 10x Genomics GermanyFabio Marsoner 10x Genomics The NetherlandsMireia Osuna Lopez EMBL Heidelberg GermanyLaura Villacorta EMBL Heidelberg GermanyTraining lab B11 50 12 50Lunch and course group photoEMBL Canteen12 50 13 50Lecture 5 Studying the shark embryo to understand the cellular origin and evolution of the vertebrate brainIdoia Quintana Urzainqui EMBL Heidelberg GermanyCourtyard Room A B13 50 14 05Coffee breakCourtyard Room A B14 05 15 05Practical session 8 qPCR cycle number determination Ahmad Al Alwash EMBL Heidelberg GermanyMonika Dabrowska 10x Genomics UKDirk J rgensen 10x Genomics GermanyFabio Marsoner 10x Genomics The NetherlandsMireia Osuna Lopez EMBL Heidelberg GermanyLaura Villacorta EMBL Heidelberg GermanyTraining lab B15 05 16 05Lecture 6 Title to be confirmedOliver Stegle EMBL Heidelberg GermanyCourtyard Room A B16 05Free evening16 05Departure to HotelIn front of ATC entrance16 25Bus to Neckarm nzplatzBus stop in front of ISG Hotel Day 4 Thursday 7 March 2024 Time Europe Berlin ProgrammeLocation08 40 09 00Bus from hotel to EMBL ATC EntranceBus stop in front of ISG Hotel09 00 09 20Practical Lecture 7 qPCR results explained Ahmad Al Alwash EMBL Heidelberg GermanyMonika Dabrowska 10x Genomics UKDirk J rgensen 10x Genomics GermanyFabio Marsoner 10x Genomics The NetherlandsMireia Osuna Lopez EMBL Heidelberg GermanyLaura Villacorta EMBL Heidelberg GermanyCourtyard Room A B09 20 10 00Practical session 9 Index PCR Ahmad Al Alwash EMBL Heidelberg GermanyMonika Dabrowska 10x Genomics UKDirk J rgensen 10x Genomics GermanyFabio Marsoner 10x Genomics The NetherlandsMireia Osuna Lopez EMBL Heidelberg GermanyLaura Villacorta EMBL Heidelberg GermanyTraining Lab B10 00 10 30Coffee breakCourtyard Room A B10 30 11 30Practical session 10 Final clean up and QC Ahmad Al Alwash EMBL Heidelberg GermanyMonika Dabrowska 10x Genomics UKDirk J rgensen 10x Genomics GermanyFabio Marsoner 10x Genomics The NetherlandsMireia Osuna Lopez EMBL Heidelberg GermanyLaura Villacorta EMBL Heidelberg GermanyTraining Lab B11 45 12 30LunchEMBL Canteen12 30 13 30Lecture 8 NGS an end point or a new beginning Vladimir Benes EMBL Heidelberg GermanyCourtyard Room A B13 30 13 50Practical Lecture 9 Bioanalyzer results explainedAhmad Al Alwash EMBL Heidelberg GermanyMonika Dabrowska 10x Genomics UKDirk J rgensen 10x Genomics GermanyFabio Marsoner 10x Genomics The NetherlandsMireia Osuna Lopez EMBL Heidelberg GermanyLaura Villacorta EMBL Heidelberg GermanyCourtyard Room A B13 50 15 50CryoStat demo session ALMF tour and imagingMonika Dabrowska 10x Genomics UKAhmad Al Alwash EMBL Heidelberg GermanyLinda Decker EMBL Heidelberg GermanyDB unit ALMF15 50 16 05Coffee breakCourtyard Room A B16 05 17 30Practical lecture and demo 10 Loop Browser and Space rangerDirk J rgensen 10x Genomics GermanyCourtyard Room A B17 30 18 00Departure to Hotel and DowntownIn front of ATC entrance18 00 19 30Free Time in the City Centre19 30 22 00Course dinner downtown Day 5 Friday 8 March 2024 Time Europe Berlin ProgrammeLocation08 40 09 00Bus from hotel to EMBL ATC EntranceBus stop in front of ISG Hotel09 00 10 30Practical session 11 Data analysis Ahmad Al Alwash EMBL Heidelberg Germany Kristy Ou EMBL Heidelberg GermanyValeriy Pak EMBL Heidelberg GermanyComputer Training Lab10 30 11 00Coffee breakComputer Training Lab11 00 12 00Practical session 12 Data analysis Ahmad Al Alwash EMBL Heidelberg Germany Kristy Ou EMBL Heidelberg GermanyValeriy Pak EMBL Heidelberg GermanyComputer Training Lab12 00 13 00LunchEMBL Canteen13 00 14 00Lecture 11 Evaluating Spatial Omics DataAnna Klemm SciLifeLab and Uppsala University SwedenCourtyard Room A B14 00 14 15Coffee breakComputer Training Lab14 15 14 45Course wrap upCourtyard Room A B14 45Departure ATC entrance Practical information Registration fees and motivation letter The course is limited to 16 participants For selection purposes please note that your application will not be considered without a letter of motivation Registration Registration fees include admission course materials COVID 19 safety measures meals and coffee breaks Academia 715PhD Student 715Industry 1225 A letter to support your visa application will be issued on request once payment of the registration fee is confirmed We recommend that you book your visa appointment as soon as possible to avoid any delay with your visa application Confirmation and payment The registration fee should be paid only after acceptance to the course The results will be announced approximately 2 3 weeks after the application deadline Motivation letter submission After you have logged in and successfully registered you will receive an email asking you to submit your motivation letter Click on the link provided and enter your motivation letter in the text box provided Alternatively you can submit your motivation letter by clicking on the link on the confirmation page directly after registering Instructions Include your relevant skills experience and qualifications showing why you would be suitable for the course Explain why you would like to attend including what you can contribute and how you think you will benefit from the course Please note The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised For detailed instructions please watch our video on how to submit a course motivation letter Further details For further information about registration and motivation letter submission please refer to the FAQ page Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of both registration fee waivers and travel grants Availability is limited to participants attending on site EMBL Courses and virtual or on site EMBO Practical Courses in Heidelberg and will be indicated during the motivation letter submission process Your place in the course is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course Travel grant The travel grant will cover the cost of travel airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Course within Europe up to 1000 for participants travelling to an EMBL Course from outside Europe up to 500 for any participant travelling to an EMBO Practical Course up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Practical Course up to 700 for any participant working in Croatia Czech Republic Estonia Greece Hungary Italy Lithuania Luxembourg Poland Slovenia and Turkey travelling to an EMBO Practical Course Registration fees are only covered for EMBO Practical Courses The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant EMBO Practical Courses only For EMBO Practical Course participants with children there is the possibility to apply for a childcare grant to offset child care costs incurred by participants or speakers when participating at a course Eligible costs include fees for a babysitter or child care facility travel costs for a caregiver or travel costs for taking the child to the meeting etc Please note that priority will be given to early stage researchers A maximum amount of 500 can be awarded per participant applying for an EMBO childcare grant Boehringer Ingelheim Fonds travel grant Applies to selected courses only Availability will be indicated during the motivation letter submission process This grant covers costs related to your attendance at the course registration travel and accommodation costs The grant is restricted to PhD students and postdocs who conduct basic biomedical research Whether you are eligible to apply for a travel grant depends on when you received your university entrance qualification e g Abitur A Levels High School Diploma Final State Examination for PhD and MD students as well as graduates the university entrance qualification must not have been obtained more than 11 years ago at the time of the envisaged course for postdocs the university entrance qualification must not have been obtained more than 13 years ago at the time of the envisaged course Application You may apply for financial assistance when submitting your motivation letter for courses In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application For the Boehringer Ingelheim Fonds Travel Grant there is a pre application question during the motivation letter submission process and if selected you will be requested to complete a standard form and documentation consisting of your travel expense estimation Selection The scientific organisers will select the recipients of all financial assistance during the motivation letter selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the course Selection is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details See our list of external funding opportunities and for further information about financial assistance please refer to the FAQ page Accommodation and shuttles Hotel Single rooms have been reserved for 5 nights 3 8 March 2024 at the ISG Hotel After the selection process selected participants should contact the hotel directly to make a booking booking code SPA24 01 We recommend that all course participants stay at the ISG Hotel which is the dedicated hotel for the course Local transport Shuttle buses will go from the ISG Hotel to EMBL and back mornings and evenings A bus schedule and location of the bus stops will be made available prior to the meeting Further details Address EMBL Heidelberg Meyerhofstra e 1 69117 Heidelberg GermanyFor further information on getting to EMBL Heidelberg visit our Travel Information page For enquiries about accommodation and local transportation please refer to the FAQ page Technical requirements and event software Event software The EMBL eCampus learning platform will be used to collaborate communicate and network with all of the course participants All participants will receive information on how to join shortly before the course We recommend using Chrome Safari or Mozilla Firefox browsers for eCampus Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page COVID 19 related questions COVID 19 information for on site events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Course Sponsor Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other events or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9...

Vladimir Benes, Dirk Jürgensen, Elisabeth Zielonka

EMBL Heidelberg

29 February 2024

UniProt for proteomics scientists

Edit

February 29, 2024 15:302024WebinarVirtual

Description UniProt is a comprehensive expert led publicly available database of protein sequence function and variation information This webinar will give a brief introduction to the UniProt website and then highlight resources available that proteomics scientists or users with large protein datasets may find useful in analysing their data This will encompass our proteomes service how to convert and retrieve ID mappings how to carry out a peptide search and how to visualise new large scale proteomics derived PTM data The webinar will then go on to introduce the UniProt Proteins API which allows researchers to access and download UniProt data alongside large scale genomic proteomics and variation data without needing prior in depth knowledge of programmatic languages Data is available for download and querying in a range of formats including XML FASTA and PEFF The API multi query search functions will be demonstrated and useful features such as searching the database by peptide finding proteomic evidence of post translational modifications and accessing a protein entry to find its peptides will be explained The UniProt Proteins API is available at www ebi ac uk proteins api doc...

Virtual

Edit

January 29, 2024 00:002024OtherEMBL Heidelberg, Virtual

Description OverviewSpeakersProgrammePractical informationSponsors PartnersIndustry workshopsMedia kit Overview This conference will take place at EMBL Heidelberg with the option to attend virtually For late registrations please contact Lea Hohmann Due to the announced railway strike in Germany there will be additional buses on Sunday evening 28 January and Monday morning 29 January from Frankfurt Airport to Heidelberg Sunday 28 01 Frankfurt Airport Terminal 1 P36 Departure 23 00 to Heidelberg Main Station Monday 29 01 Frankfurt Airport Terminal 1 P36 Departure 10 00 to EMBL More information will be shared with all participants shortly Conference overview The second edition of this workshop aims to bring the academic and industrial cryo EM communities together to evaluate how the use of cryo EM has developed 10 years on from the cryo EM resolution revolution and build upon the successful first edition held at EMBL in 2019 Showcasing high quality research in academia and industry relevant and exemplary for both cryo EM communities the meeting will provide updates on recent and ongoing methodological developments A particular focus will be on the integration of cryo ET and cryo EM with complementary imaging techniques e g imaging across scales as well as other omics technologies such as proteomics genomics and metabolomics The integration of cryo EM in the drug discovery workflow will also be examined This event is part of the iNEXT Discovery activities and is co organised with the Netherlands Cancer Institute NKI iNext Discovery is structural biology project funded from the European Commission Horizon 2020 scheme Its main aim is to provide enable access to structural biology research infrastructures for all European researchers Session topics Cryo EM in industry workflows Cryo EM applications in research Cryo EM for integrative structural biology Recent developments in cryo EM Access to cryo EM for industry and academia What past participants say about the conference The feedback from our first workshop has been very positive 100 of our participants stated that they would attend a repeat of this event This was my first experience of an EMBL advanced training centre conference and I hope it won t be my last The quality of the scientific discussion training and opportunities for networking were exceptional Mohammad Bahar University of Oxford UK This workshop gave me an excellent overview of current opinions in the field Hans Raaijmakers Thermo Fisher Scientific Speakers Keynote Speaker Carsten Sachse Forschungszentrum J lich GmbH Germany Speakers Andreas Boland University of Geneva Switzerland Doryen Bubeck Imperial College London UK Claudio Ciferri Genentech USA Tristan Croll Altos Labs USA Ilaria Ferlenghi GSK Italy Julia Mahamid EMBL Heidelberg Germany Marion MacFarlane University of Cambridge UK Francesca Ester Morreale The Francis Crick Institute UK Gergely Papp EMBL Grenoble France Anastassis Perrakis Netherlands Cancer Institute iNEXT Discovery The Netherlands Giovanna Scapin Nanoimaging Services USA Jeremy Sloan BASF Germany Andrew Ward Scripps Research USA Denis Zeyer NovAliX France Peijun Zhang eBIC Electron Biology Imaging Centre UK Ellen Zhong Princeton University USA virtual speaker Scientific Organisers Chun wa Chung GSK UK Simone Mattei EMBL Heidelberg Germany Christoph M ller EMBL Heidelberg Germany Chiara Rapisarda Sanofi France Conference Organisers Edward Avenell EMBL Heidelberg Germany Lea Hohmann EMBL Heidelberg Germany Programme Are you on social media Post using EMBLCryoEM and don t forget to tag EMBLEvents Please note that the programme is subject to change Some speakers may need to join virtually to give their talk For registered participants recorded talks will be accessible on demand for 2 weeks after the end of the event unless indicated otherwise Day 1 Monday 29 January 2024 Time Europe Berlin Speaker12 00 13 45Registration and light refreshments12 30 13 30Industry workshop Facilitating cryo EM by further automation Smart EPU and Tomo Live Software by Thermo Fishher Scientific registration required 13 45 14 00Opening remarks by Simone Mattei14 00 17 15Session 1 Cryo EM in Industry WorkflowsSession chair Chiara Rapisarda14 00 14 45Keynote Lecture Towards next generation cryo EM imaging and visualization of heterogeneous membrane remodeling systemsCarsten Sachse Forschungszentrum J lich GmbH GermanyNot available on demand14 45 15 15Rigid Fabs enable high resolution structure determination of small proteins by cryoEMClaudio Ciferri Genentech USA15 15 15 45From implementing cryo EM to effectively supporting structure based drug design an 8 year journey at NovAliXDenis Zeyer NovAliX France15 45 16 15Coffee Break16 15 16 45Novel Insight Drive Innovation for Successful AgricultureJeremy Sloan BASF GermanyNot available on demand16 45 17 00The industrialisation of cryo EM at Astex Pharmaceuticals a facility geared towards structure based drug designJoanna Brown Astex Pharmaceuticals UK17 00 17 15CryoEM a powerful tool for structure based high throughput epitope mapping of Next Generation BiologicsMadhumati Sevvana Sanofi USA17 15 17 45Coffee Break17 45 19 15Poster Session19 15 20 45Dinner in Canteen20 45 22 15After dinner drinks in ATC Rooftop Lounge Day 2 Tuesday 30 January 2024 Time Europe Berlin Speaker09 00 12 00Session 2 Cryo EM Applications in ResearchSession chair Christoph M ller09 00 09 30Controlling complementDoryen Bubeck Imperial College London UK09 30 10 00Visualising proteolytic complexes in action the small molecule switchFrancesca Ester Morreale Research Institute of Molecular Pathology Austria10 00 10 30Molecular Architecture of FADD Caspase 8 Signalling Complexes from assembly to co ordinated control of Life Death DecisionsMarion MacFarlane University of Cambridge UK10 30 11 00Coffee Break11 00 11 15Cryo EM imaging of replicative helicase loading with yeast and human proteinsJulia Greiwe The Francis Crick Institute UKNot available on demand11 15 11 30Large scale conformational changes in a spliceosomal RNA helicase induced by allosteric inhibitorsGopika S Freie Universit t Berlin Germany11 30 11 45Structural journey of an insecticidal protein against western corn rootwormGuendalina Marini CSSB GermanyNot available on demand11 45 12 00Cryo EM to study CRISPR Cas interference and adaptation for type I multiprotein effectorsInga Songailiene Vilnius University LithuaniaNot available on demand12 00 13 30Meet the speakers and Lunch12 30 13 15Industry workshop Recent Advances in Grid Technology by Quantifoil registration required 13 30 17 00Session 3 Cryo EM for Integrative Structural BiologySession chair Chun wa Chung13 30 14 00Enabling discovery by in cell structural biologyJulia Mahamid EMBL Heidelberg GermanyNot available on demand14 00 14 30Universal strategies in cryoEM to visualize small drug targetsAndreas Boland University of Geneva Switzerland14 30 15 00Accelerating vaccine discovery by multidisciplinary structural and digital innovative approaches combinationIlaria Ferlenghi GSK Italy15 00 15 30Coffee Break15 30 16 00From structure to sequence Antibody discovery using cryoEMAndrew Ward Scripps Research USA16 00 16 15Finding antibodies in cryo EM densities with CrAIChiara Rapisarda Sanofi France16 15 16 30Structural Analysis of COPI Pathway in Chlamydomonas reinhardtiiGrigory Tagiltsev Max Planck Institute of Biochemistry Germany16 30 17 00Coffee Break17 00 19 30Session 4 Recent Developments in cryo EMSession chair Anastassis Perrakis 17 00 17 30CryoDRGN Advances in deep learning for reconstructing structure and dynamics in vitro and in situ Ellen Zhong Princeton University USA remote talk17 30 18 00Physics based interactive modelling with ISOLDETristan Croll Altos Labs USA18 00 18 30EasyGrid automated sample preparation and control for cryo imaging experimentsGergely Papp EMBL Grenoble FranceNot available on demand18 30 18 45Short break18 45 19 00Towards a better understanding of sample preparation within single particle cryo EMStephen Muench University of Leeds UK19 00 19 15CCP EM Pipeliner Doppio Software tools for efficient accurate and reproducible management and automation of cryoEM processing workflowsMatthew Iadanza UKRI UK19 15 19 30Troubleshooting cryo EM sample preparation through cryo EM grid hardware past present and futureWouter Van Putte Puxano Belgium19 30 21 00Dinner in Canteen21 00 23 00After Dinner Drink Live Jazz Day 3 Wednesday 31 January 2024 Time Europe Berlin Speaker09 00 12 15Session 5 Access to cryo EM for Industry and AcademiaSession chair Simone Mattei09 00 09 30Cryo EM in industry still challenging but many opportunitiesGiovanna Scapin Nanoimaging Services USA09 30 10 00Visualizing macromolecular structures in situ by cryo electron tomographyPeijung Zhang eBIC Electron Biology Imaging Centre UKNot available on demand10 00 10 30Opportunities for using the iNEXT Discovery access program and a future outlook to services for structural biologyAnastassis Perrakis NKI iNEXT Discovery The Netherlands10 30 11 00Coffee Break11 00 11 30Structures of human tRNAs by single particle cryo EMSebastian Glatt Jagiellonian University Krakow Malopolska Centre of Biotechnology PolandNot available on demand11 30 11 45Cryo EM User facility at the Ernst Ruska Centre Forschungszentrum J lich Germany Thomas Heidler Forschungszentrum Juelich Germany11 45 12 45Round Table Discussion on Future perspectives and sustainability for cryo EM in industryPanel members Anastassis Perrakis and more to be confirmed12 45 13 00Closing Remarks and poster prizes13 00 14 30Lunch followed by departure13 15 14 15Imaging Centre ToursSeparate Registration required please await further information before event14 30Airport shuttle to Frankfurt airport terminal 1 30 EUR tickets may be purchased on site Practical information Registration fees and abstract submission On site registration fees include admission conference materials meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Virtual registration fees include access to all of the talks livestreamed and on demand and facility to submit questions On site Academia 750On site PhD Student 550On site Industry 1050Virtual Academia 225Virtual PhD Student 175Virtual Industry 275 A letter to support your visa application will be issued on request once payment of the registration fee is confirmed We recommend that you book your visa appointment as soon as possible to avoid any delay with your visa application Accredited journalists may be eligible to register for complimentary press registration Registrants may be required to provide accreditation or equivalent proof of press membership after registration Please contact Lea Hohmann for more information Confirmation and payment Registration will be on a first come first served basis Your place can only be confirmed after payment of the registration fee If you are added to our waiting list please consider taking advantage of our offerings to participate virtually On site participants Types of payments accepted are international bank transfers and credit card payments Virtual participants We are only able to accept card payments In exceptional cases we can accept bank transfers Please contact events embl de for details Abstract submission Only participants registering to attend the on site event are eligible to submit an abstract Abstracts will not be accepted from virtual participants After registration you can submit your abstract via a separate link that will be provided in the email confirmation Alternatively you can access the link on the confirmation page directly after registering The same login credentials are used for both processes Please note Abstract body The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised Title The title should not exceed 20 words Only the first word of the title should start with a capital letter and the rest should be lowercase Authors and affiliations Please fill in the author s details as requested in the online form The compulsory fields are First Name Last Name Organisation Name Affiliation or Company Country and Email Kindly mark only one author in the role of First Author and please don t forget to indicate who will be the Presenter Please enter your co authors correctly via the system by adding accounts together with their organisation institute Do not copy paste them into the body of the abstract text as they will not be indexed in the abstract book Presentation types When submitting your abstract you can apply for an oral or poster presentation A selection process will take place with the results announced 2 3 weeks after the abstract submission deadline For detailed instructions on how to submit a conference abstract follow the instructions provided in this video Please check our FAQs pages for further information on how to submit an abstract Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of registration fee waivers travel grants and childcare grants Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course or conference Travel grant The travel grant will cover the cost of travel to an on site event airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from within Europe up to 1000 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from outside Europe up to 500 for any participant travelling to an EMBO Workshop up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Workshop up to 700 for any participant working in Croatia Czech Republic Estonia Greece Hungary Italy Lithuania Luxembourg Poland Slovenia and Turkey travelling to an EMBO Workshop Registration fees are only covered for EMBO Workshops The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant There is the possibility to apply for a childcare grant to offset child care costs incurred by participants speakers and organisers when attending a conference Eligible costs include but are not limited to fees for a baby sitter or child care facility and travel costs for a caregiver Please note that priority will be given to early stage researchers In order to apply for this grant you must be registered by the abstract submission deadline There is a limited amount of funding available for the childcare grants and funds will be distributed amongst eligible applicants Application On site participants You may apply for financial assistance when submitting your abstract In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Virtual participants If you are attending virtually you can apply for financial assistance in the submission portal by the abstract deadline Read the instructions on how to apply for financial assistance Only submissions for financial assistance will be accepted Presentation abstracts cannot be submitted here and will be declined In your application you will be asked to summarise your current work answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Selection The scientific organisers will select the recipients of all financial assistance during the abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details View our list of external funding opportunities and information on attending a conference as an event reporter For further information about financial assistance please refer to the FAQ page Accommodation and travel Accommodation is not included in the conference registration fee The hotels below have rooms on hold for participants until 3 January 2024 in some cases at special rates Please email the hotel directly quoting the booking code CPP 24 01 to confirm the exact price of the room Hotel ibis HeidelbergPremier Inn Heidelberg CityISG Hotel Staycity Aparthotel HeidelbergB B HotelLeonardo Hotel Heidelberg City CentreMeininger Heidelberg Travel information For travel information please see here If you are travelling to the conference within Germany then you are eligible for the Deutsche Bahn Event Ticket called the Veranstaltungsticket in German This will result in a lower ticket price if your travel distance to Heidelberg is more than 100 km You need to provide proof of your event attendance when purchasing the ticket For more information in English see here or in German see here You can book your ticket here Conference shuttle buses Please see the bus schedule HERE as of 24 January 2024 Conference shuttle buses are free of charge for participants and depart from designated bus stops near the hotels to EMBL and back mornings and evenings The bus stops for this conference are Staycity Aparthotel Speyerer Str 7 Kurf rsten Anlage Opposite Main Train Station Premier Inn Kurf rsten Anlage 23 Leonardo Hotel Heidelberg City Center Bergheimer Str 63 Neckarm nzplatz Heidelberg Tourist Information Peterskirche Bus stop ISG Hotel Im Eichwald 19 Additional buses due to railway strike free of charge Sunday 28 01 Frankfurt Airport Terminal 1 P36 Departure 23 00 to Heidelberg Main Station Monday 29 01 Frankfurt Airport Terminal 1 P36 Departure 10 00 to EMBL View Conference shuttle bus stops and hotels in a larger map Please note that not every bus stop will be used for every event Further details Address EMBL Meyerhofstra e 1 69117 Heidelberg Germany For more information about accommodation and travel please refer to the FAQ page On site information Catering All meals and coffee breaks are included in the registration fee Our catering staff will prepare a wide variety of vegetarian meals meat and fish dishes soups pasta fresh fruit and vegetables as well as a variety of desserts Please wear your badge at all times when serving yourself No food or drinks are allowed in the auditorium Charging lockers There are lockers available next to the stairs leading down into the Auditorium You will find some of those equipped with sockets to charge your smartphone tablet etc Electricity and charging station In most places the electricity is 220 volts AC 50 cycles An adaptor and a plug that fits the German socket may be needed for your appliances laptop i e American Japanese etc A USB charging station for electronic devices is available at the registration desk EMBL merchandise If you are interested in purchasing EMBL merchandise products presented in the glass display in the registration area please email the EMBL shop to place an order or get in contact with your Course Organiser Kindly note the EMBL shop is only open upon request and all purchases must be made in cash Euros only Health and safety notes Please read EMBL s COVID 19 safety policy for on site events Do not smoke in any EMBL building Eating and drinking is prohibited in the Auditorium and all laboratories Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required The first aid room is located next to the ATC Registration Desk room 10 205 Dial the Emergency number 222 from any EMBL internal phone only Where is the accident What happened How many injured Emergency number 06221 387 7821 from mobile phones Please report all accidents to the conference officer at the registration desk In case of fire Press the nearest fire alarm button or the Emergency number 222 from any internal phone A loud fire alarm will go off if an evacuation is required On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting points Do not use the lifts Beyond first aid Please remember to bring your own medication if needed to the conference Note that the next pharmacy is a 4 minute drive from the EMBL but for many medications you will be required to see a doctor to get a prescription Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg In any case the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary Internet Wi Fi is available on campus using the EMBL Events network and the event specific password which will be provided on site The eduroam network secure worldwide roaming access service developed for the international research and education community is also available Lost and found Lost and Found items are kept at the registration desk until the end of the conference Luggage There are lockers available on site to store your luggage which require a 2 EURO coin to operate There is another luggage room on level E0 which is free to use but remains unlocked during the conference Nursing room There is a nursing room available in the ATC Rooftop Lounge on level A29 Photography During the conference an EMBL Photographer may be taking photos If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Printing We can help to print your boarding pass train ticket Please send it to events embl de and collect your print outs at the registration desk Room for prayer yoga and meditation There is a room for prayer meditation and yoga located on level E0 behind the Auditorium Please be respectful of others using the room Sightseeing A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing Travel to and from the venue During the event we provide conference shuttle buses to and from EMBL In addition there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time Information on the conference shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page Useful German expressions HelloHalloGoodbyeAuf Wiedersehen formal Tsch ss informal Good morningGuten MorgenGood afternoonGuten TagGood eveningGuten AbendGood nightGute NachtI m sorryEs tut mir leidExcuse me Entschuldigen SieHow are you Wie gehts I m fine thanks And you Mir geht es gut danke Und Dir Ihnen What is your nameWie hei en Sie formal Wie hei t du informal My name is Ich hei e Do you speak EnglishSprechen Sie englisch I don t understandIch verstehe nichtPlease speak more slowlyK nnen Sie bitte langsamer sprechenThank youDankesch nWhere is the toilet Wo ist die Toilette Please call me a taxiBitte rufen Sie mir ein TaxiHow do I get to Wie komme ich zum zur A beer two beers pleaseEin Bier zwei Bier bitteA glass of red white wine pleaseEin Glas Rot Weisswein bitteThe menu pleaseDie Speisekarte bitteIs there a local speciality Gibt es eine Spezialit t aus dieser Gegend I m vegetarianIch bin VegetarierIt was deliciousEs war hervorragendThe bill pleaseDie Rechnung bitteI have a headacheIch habe KopfschmerzenI have a sore throatIch habe HalsschmerzenMy stomach hurtsIch habe MagenschmerzenI m allergic toIch bin allergisch gegenI need a doctor who speaks EnglishIch brauche einen Arzt der englisch spricht Virtual participation What s included Access to all the livestreamed talks Video library of the recorded talks during the event and for two weeks afterwards Please note at the request of individual speakers some talks are not recorded Facility to submit questions Please note that only on site participants are able to submit abstracts and participate in the poster sessions Event platform We are using an event platform for this conference More information about the platform will be shared ahead of the conference Guidelines Do not broadcast the conference to unregistered participants You are encouraged to tweet and post about the event Tweet unless the speaker specifically says otherwise but be mindful of unpublished data Please do not capture transmit or redistribute data presented at the meeting Additional information can be found in our Code of Conduct Health and well being It is important to stay healthy and move around especially when you are attending an event virtually We have put together a few coffee break stretches and yoga videos in the conference platform for you to enjoy during the event How to ask questions Please use the Q A function in the event platform If you have any other questions you can go to the Help Desk in the event platform Click on more on the top menu and click Help Desk Time zone The programme is planned based on the Europe Berlin time zone unless otherwise stated Please take your time zone into consideration when planning your attendance Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for participants page COVID 19 related questions COVID 19 information for on site events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Partners Event partner Gold sponsor Silver sponsor Bronze sponsor Event sponsorCryoSol WorldEvent supporter Media partners EMBO Reports an EMBO Press journal International Union of Biochemistry and Molecular Biology Imaging and Microscopy a Wiley magazine Medinformatics a Bon View Publishing journal Open Biology a Royal Society journal Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information on sponsoring possibilities If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de Industry workshops For on site participants only The following industry workshops will be hosted by the sponsors of EMBL Industry Workshop Cryo EM in academia and industry during the event on Monday 29 January 2024 12 30 13 30Facilitating cryo EM by further automation Smart EPU and Tomo Live Software by Dr Rebecca Thompson and Dr Julio Ortiz Thermo Fisher Scientific on Tuesday 30 January 2024 12 30 13 15Recent Advances in Grid Technology by Dr Claire Naylor and Dr Paul Thaw Quantifoil In order to read the abstract of each workshop please click on the corresponding links above Participation in these workshop is free of charge for registered on site conference attendees The number of available places is limited first come first served You may register for and attend to both workshops All registered conference attendees will receive an email with a registration link shortly Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9 Leaderboard 728 90...

Edward Avenell, Chun-wa Chung, Simone Mattei, Christoph Mueller, Chiara Rapisarda

EMBL Industry Workshop

EMBL Heidelberg, Virtual

22 January - 26 January 2024

Exploratory analysis of biological data: data carpentry

Edit

January 22, 2024 00:002024CourseEMBL Heidelberg, Virtual

Description OverviewSpeakersProgrammePractical informationMedia kit Overview Course overview The missing step between data collection and research progress is a lack of training for researchers in crucial skills for effectively managing and analysing data often in large amounts This hands on workshop teaches researchers the fundamental data skills they need to conduct their work and provides high quality domain specific training covering the full lifecycle of data driven research The domain specific approach allows participants to tailor the data content and tools to reflect the specific data and analysis needs of different areas Audience The course is aimed at graduate students and other researchers in the life sciences who would like to learn good practices in project and data organisation and computational data analysis with R The course is ideally suited to students without prior experience in computational research but some familiarity with working with tabular data on a computer is welcome Modules Data organisation and cleaning Versioning with Git Introduction to R Data analysis and visualisation in R Data analysis with applications to genomics Learning outcomes How to organise data and some practices for more effective data handling To effectively clean and format data and automatically track any changes To use R to handle filter and summarise tabular data To use the split apply combine concept for data analysis To visualise the results of these analyses in R using the ggplot2 library To apply all of the concepts in an exploratory analysis of a typical biological dataset What past participants say about the course The best course to take first steps in data analysis I learned a lot and wholeheartedly recommend it to everyone learning to program for science purposes Magdalena Ziemianska Maj Institute of Pharmacology Polish Academy of Sciences Poland Excellent course to learn basics of R A very friendly group of instructors who were easy to interact with and patient with all the queries we had Also the organisation team made it very easy for us the pre and post course preparations and also during the stay Balagopal Pai University of Regensburg Germany Speakers Speakers trainers and staff Renato Alves EMBL Heidelberg Germany Gaurav Diwan University of Heidelberg Germany Stella Fragkouli Center for Research and Technology Hellas CERTH Greece virtual Ece Kartal University of Heidelberg Germany Supriya Khedkar EMBL Heidelberg Germany Eleonora Mastrorilli EMBL Heidelberg Germany Lisanna Paladin EMBL Heidelberg Germany Nikos Pechlivanis Center for Research and Technology Hellas CERTH Greece virtual Fotis Psomopoulos Center for Research and Technology Hellas CERTH Greece virtual Christian Schudoma EMBL Heidelberg Germany Francesco Tabaro EMBL Rome Italy Vasileios Vasileiou Center for Research and Technology Hellas CERTH Greece virtual Tristan Wiessalla EMBL Rome Italy virtual Scientific organisers Renato Alves EMBL Heidelberg Germany Lisanna Paladin EMBL Heidelberg Germany Fotis Psomopoulos Center for Research and Technology Hellas CERTH Greece Christian Schudoma EMBL Heidelberg Germany Course organisers Iva Gavran Course and conference officer EMBL Heidelberg Germany Swetlana Krez Training Lab Technician EMBL Heidelberg Germany Programme Are you on social media Post using EMBLDataCarpentry and don t forget to tag EMBLEvents Some pre course work in the form of preinstalling software and attending a pre course onboarding session will be required Details will be shared in advance of the course Some speakers may need to join virtually to give their lecture or Q A and the programme is subject to change On boarding session Monday 15 January 2024 Time Europe Berlin SpeakerLocation15 00 17 00On boarding session and Q A regarding software installationRenato Alves EMBL Heidelberg GermanyLisanna Paladin EMBL Heidelberg GermanyFrancesco Tabaro EMBL Rome Italyvirtual Day 1 Monday 22 January 2024 Time Europe Berlin SpeakerLocation10 45 11 00Bus from hotel to EMBL ATC EntranceISG Hotel11 00 11 15Welcome and house notes and course overview by scientific organisersCourtyard Room A B11 15 12 15FlashtalksCourtyard Room A B12 15 13 15LunchEMBL Canteen13 15 14 15Lecture Data Organization in SpreadsheetsLisanna Paladin EMBL Heidelberg GermanyCourtyard Room A B14 15 14 35Coffee breakCourtyard Foyer14 35 16 05Lecture OpenRefine for Data CleaningLisanna Paladin EMBL Heidelberg GermanyCourtyard Room A B16 05 16 20Coffee breakCourtyard Foyer16 20 17 50Lecture OpenRefine for Data Cleaning continued Lisanna Paladin EMBL Heidelberg GermanyCourtyard Room A B17 50 18 50Networking sessionCourtyard Room A B18 50 19 50DinnerEMBL Canteen19 50 20 00Shuttle bus to hotelATC Entrance Day 2 Tuesday 23 January 2024 Time Europe Berlin SpeakerLocation08 40 08 55Bus from hotel to EMBL ATC EntranceISG Hotel09 00 11 00Practical session Versioning with Git using RStudio Fotis Psomopoulos Center for Research and Technology Hellas CERTH Greece virtual Courtyard Room A B11 00 11 30Coffee breakCourtyard foyer11 30 12 30Practical session Versioning with Git using RStudio Fotis Psomopoulos Center for Research and Technology Hellas CERTH Greece virtual Courtyard Room A B12 30 13 30Lunch breakEMBL Canteen13 30 15 00Practical session Introduction to REleonora Mastrorilli EMBL Heidelberg GermanyCourtyard Room A B15 00 15 30Coffee breakCourtyard foyer15 30 16 50Practical session Introduction to REleonora Mastrorilli EMBL Heidelberg GermanyCourtyard Room A B16 50 17 10Coffee breakCourtyard foyer17 10 18 30Practical session Introduction to REleonora Mastrorilli EMBL Heidelberg GermanyCourtyard Room A B18 30 19 30DinnerEMBL Canteen19 45 19 55Shuttle bus to ISG HotelATC Entrance Day 3 Wednesday 24 January 2024 Time Europe Berlin SpeakerLocation08 40 08 55Bus from hotel to EMBL ATC EntranceISG Hotel 09 00 11 00Practical session Data manipulation with dplyrSupriya Khedkar EMBL Heidelberg GermanyCourtyard Room A B11 00 11 30Coffee breakCourtyard foyer11 30 12 30Practical session Data manipulation with dplyrSupriya Khedkar EMBL Heidelberg GermanyCourtyard Room A B12 30 13 30Lunch breakEMBL Canteen13 30 15 00Practical session Data visualisation with ggplot2Francesco Tabaro EMBL Rome ItalyEleonora Mastrorilli EMBL Heidelberg GermanyCourtyard Room A B15 00 15 30Group photo and Coffee breakCourtyard foyer15 30 16 50Practical session Data visualisation with ggplot2Francesco Tabaro EMBL Rome ItalyEleonora Mastrorilli EMBL Heidelberg GermanyCourtyard Room A B16 50 17 10Coffee breakCourtyard foyer17 10 18 30Practical session Data visualisation with ggplot2Francesco Tabaro EMBL Rome ItalyEleonora Mastrorilli EMBL Heidelberg GermanyCourtyard Room A B18 30 19 30DinnerEMBL Canteen19 45 19 55Shuttle bus to ISG HotelATC Entrance Day 4 Thursday 25 January 2024 Time Europe Berlin SpeakerLocation08 40 08 55Bus from hotel to EMBL ATC EntranceISG Hotel09 00 09 50Lecture Data visualisation with ggplot2Francesco Tabaro EMBL Rome ItalyEleonora Mastrorilli EMBL Heidelberg GermanyCourtyard Room A B09 50 10 00Short coffee breakCourtyard foyer10 00 10 50Practical session Data analysis with applications to genomicsGaurav Diwan University of Heidelberg GermanyCourtyard Room A B10 50 11 20Coffee breakCourtyard foyer11 20 12 20Practical session Data analysis with applications to genomicsRenato Alves EMBL Heidelberg GermanyCourtyard Room A B12 20 13 20Lunch breakEMBL Canteen13 20 14 50Practical session Data analysis with applications to genomicsRenato Alves EMBL Heidelberg GermanyCourtyard Room A B14 50 15 20Coffee breakCourtyard foyer15 20 17 00Practical session Data analysis with applications to genomicsRenato Alves EMBL Heidelberg GermanyCourtyard Room A B17 00 17 30Shuttle bus to downtownATC Entrance 17 30 19 00Free time19 00 21 30Downtown dinnertbd Day 5 Friday 26 January 2024 Time Europe Berlin SpeakerLocation08 40 08 55Bus from hotel to EMBL ATC EntranceISG Hotel09 00 10 30Practical session Data analysis with applications to genomicsFrancesco Tabaro EMBL Rome ItalyCourtyard Room A B10 30 11 00Coffee breakCourtyard foyer11 00 12 00Practical session Data analysis with applications to genomicsFrancesco Tabaro EMBL Rome ItalyCourtyard Room A B12 00 13 00Lunch breakEMBL Canteen13 00 14 00Debrief and wrap upCourtyard Room A B14 00 14 30Shuttle bus to Heidelberg main train stationATC Entrance Practical information Registration fees and motivation letter The course is limited to 15 on site and 15 virtual participants For selection purposes please note that your application will not be considered without a letter of motivation and answering all additional questions Registration Onsite registration fees include admission course materials meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Virtual registration fees include access to live streamed course content lectures practical sessions discussion rounds as well as any learning activities in the virtual learning platform Onsite Academia 425Onsite PhD Student 425Onsite Industry 750Virtual Academia 190Virtual PhD Student 190Virtual Industry 250 A letter to support your visa application will be issued on request once payment of the registration fee is confirmed We recommend that you book your visa appointment as soon as possible to avoid any delay with your visa application Confirmation and payment The registration fee should be paid only after acceptance to the course The results will be announced approximately 2 3 weeks after the application deadline Motivation letter submission After you have logged in and successfully registered you will receive an email asking you to submit your motivation letter Click on the link provided and enter your motivation letter in the text box provided Alternatively you can submit your motivation letter by clicking on the link on the confirmation page directly after registering Instructions Include your relevant skills experience and qualifications showing why you would be suitable for the course Explain why you would like to attend including what you can contribute and how you think you will benefit from the course Please note The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised For detailed instructions please watch our video on how to submit a course motivation letter Further details For further information about registration and motivation letter submission please refer to the FAQ page Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of registration fee waivers travel grants and childcare grants Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course Travel grant The travel grant will cover the cost of travel airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Course within Europe up to 1000 for participants travelling to an EMBL Course from outside Europe up to 500 for any participant travelling to an EMBO Practical Course up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Practical Course up to 700 for any participant working in Croatia Czech Republic Estonia Greece Hungary Italy Lithuania Luxembourg Poland Slovenia and Turkey travelling to an EMBO Practical Course Registration fees are only covered for EMBO Practical Courses The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant There is the possibility to apply for a childcare grant to offset childcare costs incurred by participants speakers and organisers when attending a conference Eligible costs include but are not limited to fees for a babysitter or child care facility and travel costs for a caregiver Please note that priority will be given to early stage researchers In order to apply for this grant you must be registered by the abstract submission deadline There is a limited amount of funding available for the childcare grants and funds will be distributed amongst eligible applicants Application You may apply for financial assistance when submitting your motivation letter for courses In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Selection The scientific organisers will select the recipients of all financial assistance during the motivation letter selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the course Selection is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details See our list of external funding opportunities and for further information about financial assistance please refer to the FAQ page Accommodation and travel Travel information For travel information please see here If you are travelling to the conference within Germany then you are eligible for the Deutsche Bahn Event Ticket called the Veranstaltungsticket in German This will result in a lower ticket price if your travel distance to Heidelberg is more than 100 km You need to provide proof of your event attendance when purchasing the ticket For more information in English see here or in German see here You can book your ticket here Hotel Accommodation is not included in the registration fee On site participants are expected to book and pay for their own accommodation Single rooms have been reserved for 5 nights 21 26 January 2024 at ISG Hotel After the selection process selected participants should contact the hotel directly to make a booking with a booking code code of your course e g DTC24 01 by the deadline of 24 December 2023 We recommend that all course participants stay at the dedicated hotel for the course Local transport Shuttle buses will go from the ISG Hotel to EMBL and back mornings and evenings A bus schedule and location of the bus stops will be made available prior to the meeting Further details Address EMBL Meyerhofstra e 1 69117 Heidelberg Germany For more information about accommodation and travel please refer to the FAQ page On site information Catering All meals and coffee breaks are included in the on site registration fee Our catering staff will prepare a wide variety of vegetarian meals meat and fish dishes soups pasta fresh fruit and vegetables as well as a variety of desserts Please wear your badge at all times when serving yourself No food or drinks are allowed in the laboratories Electricity and charging station In most places the electricity is 220 volts AC 50 cycles An adaptor and a plug that fits the German socket may be needed for your appliances laptop i e American Japanese etc A USB charging station for electronic devices is available at the registration desk EMBL Merchandise If you are interested in purchasing EMBL merchandise products presented in the glass display in the registration area please email the EMBL shop to place an order or get in contact with your Course Organiser Kindly note the EMBL shop is only open upon request and all purchases must be made in cash Euros only Health and safety notes Please read EMBL s COVID 19 safety policy for on site events Do not smoke in any EMBL building Eating and drinking is prohibited in all laboratories Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required The first aid room is located next to the ATC Registration Desk room 10 205 Dial the Emergency number 222 from any EMBL internal phone only Where is the accident What happened How many injured Emergency number 06221 387 7821 from mobile phones Please report all accidents to the conference officer at the registration desk In case of fire Press the nearest fire alarm button or the Emergency number 222 from any internal phone A loud fire alarm will go off if an evacuation is required On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting points Do not use the lifts Beyond first aid Please remember to bring your own medication if needed to the conference Note that the next pharmacy is a 4 minute drive from the EMBL but for many medications you will be required to see a doctor to get a prescription Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg In any case the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary Internet Wi Fi is available on campus Log in using the EMBL Events network and the event specific password which will be provided on site The eduroam network secure worldwide roaming access service developed for the international research and education community is also available Lost and found Lost and Found items are kept at the registration desk until the end of the conference Luggage There are lockers available on site to store your luggage which require a 2 EURO coin to operate There is another luggage room on level E0 which is free to use but remains unlocked during the conference Nursing room There is a nursing room available in the ATC Rooftop Lounge on level A29 Photography During the conference an EMBL Photographer may be taking photos If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Printing We can help to print your boarding pass train ticket Please send it to events embl de and collect your print outs at the registration desk Room for prayer yoga and meditation There is a room for prayer meditation and yoga located on level E0 behind the Auditorium Please be respectful of others using the room Sightseeing A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing Travel to and from the venue During the event we provide conference shuttle buses to and from EMBL In addition there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time Information on the shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page Map to walk from ISG Hotel to EMBL Additional information Address EMBL Heidelberg Meyerhofstra e 1 69117 Heidelberg Germany ATC orientation map Please find additional information including FAQs terms and conditions and travelling to EMBL on our Information for Participants page Technical requirements and event software Technical requirements Below you will find the software and technical requirements for this course On site participants need to bring their own laptops which will be used to remotely access EMBL virtual machines with pre installed software All participants will be requested to install software before the course Please make sure to bring the laptop with the installed software to the course You will need admin rights to install the software required to access the virtual machines If you do not have admin rights please contact your technical support team in advance to make sure the software can be installed If you have a non standard HDMI port other than type A you need to bring an adaptor Keyboard and PC mouse are available for use with a standard USB port If you have a different port type such as USB C you will need to bring your own Event software The EMBL eCampus learning platform will be used to collaborate communicate and network with all of the course participants All participants will receive information on how to join shortly before the course We recommend using Chrome Safari or Mozilla Firefox browsers for eCampus Additional information Please find additional information including FAQs terms and conditions and travelling to EMBL on our Information for Participants page Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9...

Renato Alves, Lisanna Paladin, Fotis E. Psomopoulos, Christian Schudoma

EMBL Heidelberg, Virtual

18 January 2024

Automated annotation in UniProt

Edit

January 18, 2024 15:302024WebinarVirtual

Virtual

17 January 2024

An introduction to EMBL-EBI resources

Edit

January 17, 2024 15:302024WebinarVirtual

Description EMBL EBI is the home of the world s most comprehensive range of freely available molecular databases and resources Our resources help researchers share and analyse data and perform complex queries in many different ways Join us for a tour of the core data resources at EMBL EBI During this webinar we will introduce the types of data available how you can search for data and the various ways of getting assistance We will also discuss the role of EMBL EBI in making data open and accessible and how you can include EMBL EBI data in your workflows We will also provide information on further online training to help you learn more about specific topics in bioinformatics and EMBL EBI resources including an introduction to the training collections The collections bring together videos and online tutorials on a specific topic to help get started...

Virtual

14 December 2023

Uncovering protein function with UniProt

Edit

December 14, 2023 15:302023WebinarVirtual

Virtual

12 December 2023

Edit

November 30, 2023 00:002023CourseVirtual

Description Genetic variation between individuals results in a range of human phenotypes Variants that fall within coding regions of genes generally have direct and effects on the proteins encoded by the genes with which they overlap This four hour virtual workshop will provide participants with an opportunity to gain hands on experience of using EMBL EBI tools and resources to assess the effects of genetic variants on the structure and function of proteins in a common workflow During the course a single example will be used throughout using different EMBL EBI tools resources at each stage of the analysis pipeline The example will involve running a VCF file through the Ensembl Variant Effect Predictor VEP then following links to UniProt PDBe and AlphaFoldDB for further variant information and interpreation Virtual courseThis course will take place on Zoom Trainers will be available to assist answer questions and provide further explanations during the Zoom...

Meredith Willmott

Virtual

29 November 2023

Studying metabolites and small molecules with MetaboLights and ChEBI

Edit

November 29, 2023 15:302023WebinarVirtual

Description Metabolites are small molecules that play important roles in biological and cellular processes They act as signalling molecules serve as cofactors involved in energy production and storage and thus responsible for the maintenance growth and development of living organisms In this webinar we will first introduce metabolomics which focuses on the comprehensive analysis of metabolites within biological systems such as cells biofluids tissues or organisms from different ecosystems and health and environmental backgrounds In the second part of the webinar we will show how metabolite data is represented in MetaboLights an open access cross species and cross technique database for metabolomic experiments and derived information Studies in MetaboLights contain information across study design sample origin collection processing spectral data measurement data processing and metabolite identification The re use of data from MetaboLights can take various forms from identified metabolites towards interpretation with pathways reactions literature to a matrix for statistical modelling or even re processing of raw data In the final part of the webinar we will introduce MetaboLights partner database ChEBI that focuses on the nomenclature structure and biological properties of small molecules...

Virtual

28 November - 1 December 2023

Subcortical sensory circuits: visual, auditory, somatosensory, and beyond

Edit

November 28, 2023 00:002023ConferenceEMBL Heidelberg, Virtual

Description OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Conference overview Subcortical sensory circuits play a fundamental role in the perception of the outside world However they are often thought of as relay stations that passively transmit sensory information to the cortex or simple effectors of behavioral reflexes Recent studies however suggest that subcortical pathways also perform sophisticated computations such as integrating peripheral information among many sensory pathways and the animal s internal states This meeting will gather leading researchers in the field to discuss different subcortical circuits involving various sensory modalities and revisit their increasingly complex and interconnected contributions to perception behavior and cognition Furthermore we will delve into various topics which often play an interconnected role with sensory perception and are crucial to a detailed yet holistic understanding of perceptual circuits Topics Visual processing by the thalamus Circuits of the colliculus vision and multisensory integration Multisensory Integration and higher order thalamic nuclei Thalamocortical circuits of somatosensation Thalamic circuits for auditory perception The subcortical influence on decision making Development of subcortical circuits in mice and non human primates Thalamic modulation by glia The neuronal circuits underlying sleep Please see EMBL s COVID 19 safety recommendations if attending the on site event Speakers Keynote speakers Sabine Kastner Princeton University USA Karel Svoboda Allen Institute USA Speakers Victoria Abraira Rutgers University USA Mark Andermann Harvard Medical School USA Hiroki Asari EMBL Rome Italy Martha Bickford University of Louisville USA Christian B chel University Hospital Hamburg Eppendorf Germany Laura Busse Ludwig Maximilians University Munich Germany Eunji Cheong Yonsei University Republic of Korea Christine Constantinople NYU Center for Neural Science USA Karl Farrow NERF Belgium Maria Geffen University of Pennsylvania USA Mike Halassa Tufts University USA Maria Florencia Iacaruso Francis Crick Institute UK Max J sch Institute of Science and Technology Austria Andrew King Oxford University UK Liang Liang Yale University USA Anita L thi University of Lausanne Switzerland David McAlpine Macquarie University Australia Carl Petersen EPFL Switzerland Santiago Rompani EMBL Rome Italy Tomomi Shimogori RIKEN Center for Brain Science Japan Scientific organisers Hiroki Asari EMBL Rome Italy Martha Bickford University of Louisville USA Carl Petersen EPFL Switzerland Santiago Rompani EMBL Rome Italy Conference organiser Aline Schnieder EMBL Heidelberg Germany Programme Got something to say Tweet it EMBOSensoryCircuits Programme is preliminary and subject to change For registered participants recorded talks will be accessible on demand for 2 weeks after the end of the event unless indicated otherwise Day 1 Tuesday 28 November 2023 Time Europe Berlin Session Speaker12 00 13 00Registration and light refreshments13 00 13 15Opening remarks13 15 14 15Keynote lecture Computation in multi regional neural circuits with thalamus in the middleKarel Svoboda Allen Institute USANot available on demand14 15 15 00Better research panel discussion Improving job prospects for postdocs and tackling status inequality in hiringChair Santiago Rompani EMBL Rome ItalyPanellists Victoria Abraira Rutgers University USALaura Busse LMU Munich GermanyTomomi Shimogori RIKEN Center for Brain Science JapanKarel Svoboda Allen Institute USANot available on demand15 00 15 30Coffee Break and Meet the speakerSession 1 Subcortical influence on decision makingSession Chair Hiroki Asari15 30 16 00Thalamocortical control of cell type specificity drives a circuit for processing whisker related information in mouse barrel cortexTomomi Shimogori RIKEN Center for Brain Science Japan16 00 16 15What is a place cell Mayank Mehta University of California Los Angeles USA16 15 16 45Neural mechanisms of inferenceChristine Constantinople NYU USANot available on demand16 45 17 00Subcortical threats processing and non Hebbian consolidation of transient experiencesIslam Faress DANDRITE Aarhus University Denmark17 00 17 15The neural basis of defensive behaviour evolution in Peromyscus miceKatja Reinhard SISSA ItalyNot available on demand17 15 17 30Complex synaptic mechanisms between superior colliculus and thalamus during multisensory processesAnna Vir g Bakacsi Semmelweis University HungaryNot available on demand17 30 18 00Speed Networking 18 00 19 30Dinner19 30 21 00Welcome reception After dinner drinks Day 2 Wednesday 29 November 2023 Time Europe Berlin Session Speaker Session 2 Subcortical circuits for auditory perceptionSession Chair Santiago Rompani09 00 09 30Attentional modulation of subcortical auditory centres and sensory receptors in complex listening tasksDavid McAlpine Macquarie University Australia09 30 09 45Effective population coding of sound location by noisy neurons from the dorsal cortex of inferior colliculus in awake passively listening miceJuan Carlos Boffi EMBL Heidelberg GermanyNot available on demand09 45 10 15Subcortical circuits for auditory prediction and learningMaria Geffen University of Pennsylvania USA10 15 10 45Coffee Break and Meet the speakers10 45 11 00Network state changes in auditory thalamus represent learned outcomesJan Gr ndemann Deutsches Zentrum f r Neurodegenerative Erkrankungen DZNE Germany11 00 11 30Subcortical contributions to auditory processing and behaviourAndrew King University of Oxford UK11 30 12 00Flash talks odd numbers 39 Borb ly S ndor 41 Guarascio Domenico 43 Kamm Gretel 47 Magyar Aletta 49 Micheli Pietro 51 Myers Thomas 53 Nuttin Bram 55 Qu Mengdi 57 Schmidt Florian 61 Tortella Lorenza 63 Trpevski Daniel 65 Sumser Anton 67 Whitley JamesNot available on demand12 00 13 00Lunch and Meet the speakers Session 3 Visual processing by the thalamusSession Chair Martha Bickford13 00 13 30Functional organization of feeding related signals in the lateral parabrachial nucleusMark Andermann Harvard Medical School USA13 30 13 45Binocular integration of RGC boutons in the LGN can encode binocular summationTjasa Lapanja EMBL Rome Italy13 45 14 15Retinal ganglion cell axon binocularity in the mouseSantiago Rompani EMBL Rome ItalyNot available on demand14 15 14 45Coffee Break and Meet the speakers14 45 15 15Selective convergence of distinct excitatory inputs in the visual thalamus reinforces motion processingLiang Liang Yale University USANot available on demand15 15 15 30Flexible regulation of behavioural strategy during approach avoidance conflicts by the lateral geniculate nucleusAlice Monica Koltchev Sainsbury Wellcome Centre UK15 30 16 00Spiking activity in the visual thalamus is coupled to pupil dynamics across temporal scalesLaura Busse Ludwig Maximilians University of Munich Germany16 00 16 15Individual thalamic inhibitory interneurons are functionally specialized towards distinct visual featuresFiona Muellner Institute of Molecular and Clinical Ophthalmology Basel IOB SwitzerlandNot available on demand16 15 16 30An interpretable spline GLM to assess feedforward and feedback processing in mouse dLGNAnn Hossam Mohamed Kotkat Ludwig Maximilians University of Munich Germany16 30 18 30Poster Session odd numbers with beer and snacksView poster listing here18 30Free evening Day 3 Thursday 30 November 2023 Time Europe Berlin Session SpeakerSession 4 Colliculus circuits vision and multisensory integrationSession Chair Carl Petersen09 00 09 30Corollary discharge signals shape visuomotor transformation in the superficial superior colliculusMaximilian J sch Institute of Science and Technology Austria AustriaNot available on demand09 30 09 45Retinal origin of orientation but not direction selective maps in the superior colliculusDaniel de Malmazet MRC Laboratory of Molecular Biology UK09 45 10 15What does the eye tell the brain in vivo Hiroki Asari EMBL Rome ItalyNot available on demand10 15 10 45Coffee Break and Meet the speakers10 45 11 15Brain wide inputs to the superior colliculus and the modulating of innate behaviorsKarl Farrow VIB Belgium11 15 11 30Dendritic properties shape the responses of collicular wide field neurons to behaviorally relevant stimuliNorma K hn NERF Belgium11 30 11 45Characterization of visual response properties and connectivity of wide field vertical neurons in the mouse superior colliculusElise Savier University of Michigan USA11 45 12 15Flexible approach strategies support interceptive pursuit behaviour in miceMaria Florencia Iacaruso Francis Crick Institute UK12 15 13 30Lunch and Meet the speakersSession 5 Thalamocortical circuits of somatosensationSession Chair Hiroki Asari13 30 14 00Neuronal circuits for goal directed sensorimotor learningCarl Petersen EPFL Switzerland14 00 14 15Neural encoding of sensory surprise in the mouse brainDiego Benusiglio EMBL Rome Italy14 15 14 45Glial control of thalamic sensory processingEunji Cheong Yonsei University Republic of Korea14 45 15 15Coffee Break and Meet the speakers15 15 15 45Wired for Touch the story of how touch shapes our livesVictoria Abraira Rutgers University USA15 45 16 15The interaction of subcortical and cortical sensory circuits in pain processingChristian B chel University Hospital Hamburg Eppendorf Germany16 15 16 45Flash talks even numbers 38 Boone Howard 40 Ferrarese Leiron 42 Han Xu 44 Li Chen 46 Liu Chen 48 Mason Kierra 50 Molotkov Dmitry 52 Naeem Nazratan 54 Puvvada Madhuri 56 Sans Dublanc Arnau 58 Sokoloski Sacha 60 Susi Frank 62 Tripodi Matteo 64 Uran Cem 66 Gaspar Patricia 68 Zemmouri FirdaoussNot available on demand16 45 18 45Poster Session even numbers with beer and snacksView poster listing here18 45 20 30Conference dinner20 30 23 00Conference party in ATC Rooftop Lounge Day 4 Friday 1 December 2023 Time Europe Berlin Session SpeakerSession 6 Multisensory Integration and higher order thalamic nucleiSession Chair Santiago Rompani09 00 10 00Keynote lecture The cognitive visual thalamusSabine Kastner Princeton University USA10 00 10 15Parallel corticothalamic pathways from postrhinal cortex to pulvinar synaptic and physiological propertiesJulia Zaltsman Brown University USANot available on demand10 15 10 45Thalamic regulation of prefrontal dynamics in decision makingMichael Halassa Tufts University USA10 45 11 15Coffee Break and Meet the speakers11 15 11 45Integration of driver like inputs across the visual thalamusMartha Bickford University of Louisville USA11 45 12 15Being disconnected but remaining vigilant the neuroscience of opposing sleep functionsAnita Luthi University of Lausanne Switzerland12 15 12 30Closing Remarks and Poster Prize12 30 12 45Packed lunch and departure Practical information Registration fees and abstract submission On site registration fees include admission conference materials COVID 19 safety measures meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Virtual registration fees include access to all of the talks livestreamed and on demand and facility to submit questions On site Academia 450On site PhD Student 350On site Industry 750Virtual Academia 200Virtual PhD Student 150Virtual Industry 250 A letter to support your visa application will be issued on request once payment of the registration fee is confirmed We recommend that you book your visa appointment as soon as possible to avoid any delay with your visa application Accredited journalists may be eligible to register for complimentary press registration Registrants may be required to provide accreditation or equivalent proof of press membership after registration Please contact Aline Schnieder for more information Please note that we do not offer complimentary registrations for editors of scientific journals Confirmation and payment Registration will be on a first come first served basis Your place can only be confirmed after payment of the registration fee If you are added to our waiting list please consider taking advantage of our offerings to participate virtually On site participants Types of payments accepted are international bank transfers and credit card payments Virtual participants We are only able to accept card payments In exceptional cases we can accept bank transfers Please contact events embl de for details Abstract submission Only participants registering to attend the on site event are eligible to submit an abstract Abstracts will not be accepted from virtual participants After registration you can submit your abstract via a separate link that will be provided in the email confirmation Alternatively you can access the link on the confirmation page directly after registering The same login credentials are used for both processes Please note Abstract body The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised Title The title should not exceed 20 words Only the first word of the title should start with a capital letter and the rest should be lowercase Authors and affiliations Please fill in the author s details as requested in the online form The compulsory fields are First Name Last Name Organisation Name Affiliation or Company Country and Email Kindly mark only one author in the role of First Author and please don t forget to indicate who will be the Presenter Please enter your co authors correctly via the system by adding accounts together with their organisation institute Do not copy paste them into the body of the abstract text as they will not be indexed in the abstract book Presentation types When submitting your abstract you can apply for an oral or poster presentation A selection process will take place with the results announced 2 3 weeks after the abstract submission deadline For detailed instructions on how to submit a conference abstract follow the instructions provided in this video Please check our FAQs pages for further information on how to submit an abstract Financial assistance EMBO Workshops We are currently working on securing funding for all virtual participants and ask that you please apply for financial assistance for both on site and virtual participation Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course or conference Travel grant The travel grant will cover the cost of travel to an on site event airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from within Europe up to 1000 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from outside Europe up to 500 for any participant travelling to an EMBO Workshop up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Workshop up to 700 for any participant working in Croatia Czech Republic Estonia Greece Hungary Italy Lithuania Luxembourg Poland Slovenia and Turkey travelling to an EMBO Workshop Registration fees are only covered for EMBO Workshops The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant EMBO Workshops only For EMBO Workshop participants with children there is the possibility to apply for a childcare grant to offset child care costs incurred by participants or speakers when participating at a conference Eligible costs include fees for a baby sitter or child care facility travel costs for a caregiver or travel costs for taking the child to the meeting etc Please note that priority will be given to early stage researchers A maximum amount of 500 can be awarded per participant applying for an EMBO childcare grant In order to apply for this grant for EMBO Workshops you must be registered by the abstract submission deadline Application On site participants You may apply for financial assistance when submitting your abstract In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Virtual participants If you are attending virtually you can apply for financial assistance in the submission portal by the abstract deadline Read the instructions on how to apply for financial assistance Only submissions for financial assistance will be accepted Presentation abstracts cannot be submitted here and will be declined In your application you will be asked to summarise your current work answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Selection The scientific organisers will select the recipients of all financial assistance during the abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details View our list of external funding opportunities and information on attending a conference as an event reporter For further information about financial assistance please refer to the FAQ page Accommodation and shuttles Accommodation is not included in the conference registration fee As further changes in our events are possible due to COVID 19 you should book flights trains and hotels with flexible options and favourable cancellation conditions The hotels below have rooms on hold for participants until 23 August 2023 in some cases at special rates Please email the hotel directly quoting the booking code SSC23 01 to confirm the exact price of the room Hotel AnlageHotel ibis HeidelbergPremier Inn Heidelberg CityHotel Bayrischer Hof ISG Hotel Staycity Aparthotel HeidelbergB B HotelLeonardo Hotel Heidelberg City CentreHotel Vier Jahreszeiten HeidelbergExzellenz HotelMeininger HeidelbergHotel Holl nder Hof Hotel Monpti Conference shuttle buses Conference shuttle buses are free of charge for participants and depart from designated bus stops near the hotels to EMBL and back mornings and evenings You can now find the conference bus schedule here The bus stops for this conference are Staycity Aparthotel Speyerer Str 7 Kurf rsten Anlage Opposite Main Train Station Premier Inn Kurf rsten Anlage 23 Leonardo Hotel Heidelberg City Center Bergheimer Str 63 Neckarm nzplatz Heidelberg Tourist Information ISG Hotel Im Eichwald 19 View Conference shuttle bus stops and hotels in a larger map Please note that not every bus stop will be used for every event Further details Address EMBL Meyerhofstra e 1 69117 Heidelberg Germany For further information on getting to EMBL Heidelberg visit Public Transportation to the Venue For information about accommodation and local transportation please refer to the FAQ page On site information Catering All meals and coffee breaks are included in the registration fee Our catering staff will prepare a wide variety of vegetarian meals meat and fish dishes soups pasta fresh fruit and vegetables as well as a variety of desserts Please wear your badge at all times when serving yourself No food or drinks are allowed in the auditorium Charging lockers There are lockers available next to the stairs leading down into the Auditorium You will find some of those equipped with sockets to charge your smartphone tablet etc Electricity and charging station In most places the electricity is 220 volts AC 50 cycles An adaptor and a plug that fits the German socket may be needed for your appliances laptop i e American Japanese etc A USB charging station for electronic devices is available at the registration desk EMBL merchandise If you are interested in purchasing an EMBL souvenir products presented in the glass display in the registration area please ask at the registration desk for more information Health and safety notes Please read EMBL s COVID 19 safety policy for on site events Do not smoke in any EMBL building Eating and drinking is prohibited in the Auditorium and all laboratories Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required The first aid room is located next to the ATC Registration Desk room 10 205 Dial the Emergency number 222 from any EMBL internal phone only Where is the accident What happened How many injured Emergency number 06221 387 7821 from mobile phones Please report all accidents to the conference officer at the registration desk In case of fire Press the nearest fire alarm button or the Emergency number 222 from any internal phone A loud fire alarm will go off if an evacuation is required On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting points Do not use the lifts Beyond first aid Please remember to bring your own medication if needed to the conference Note that the next pharmacy is a 4 minute drive from the EMBL but for many medications you will be required to see a doctor to get a prescription Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg In any case the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary Internet Wi Fi is available everywhere on the premises using the EMBL Events network and the event specific password which will be provided on site The eduroam network secure world wide roaming access service developed for the international research and education community is also available Lost and found Lost and Found are kept at the registration desk until the end of the conference Luggage There are lockers available on site to store your luggage which require a 2 EURO coin to operate There is another luggage room on level E0 which is free to use but remains unlocked during the conference Nursing room There is a nursing room available in the ATC Rooftop Lounge on level A29 Photography During the conference an EMBL Photographer may be taking photographs If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Printing We can help printing your boarding passes train ticket Please send it to events embl de and collect your print outs at the registration desk Room for prayer yoga and meditation There is a room for prayer mediation and yoga located on level E0 behind the Auditorium Please be respectful of other participants using the room Sightseeing A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing Travel to and from the venue During the event we provide conference shuttle buses to and from EMBL In addition there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time Information on the conference shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page Useful German expressions Where is the nearest Covid test centre Wo ist das n chste Covid Testzentrum HelloHalloGoodbyeAuf WiedersehenGood morningGuten MorgenGood afternoonGuten TagGood eveningGuten AbendGood nightGute NachtI m sorryTut mir leidExcuse me Entschuldigen SieHow are you Wie gehts I m fine thanks And you Mir geht es gut danke und dir Ihnen What is your nameWie heisst du Wie heissen Sie My name isIch heisseDo you speak EnglishSprechen Sie Englisch I don t understandIch verstehe nichtPlease speak more slowlyK nnen Sie bitte langsamer sprechenThank youDankesch nWhere is the toilet Wo ist die Toilette Please call me a taxiBitte rufen Sie mir ein TaxiHow do I get to Wie komme ich zum zur A beer two beers pleaseEin Bier zwei Bier bitteA glass of red white wine pleaseEin Glas Rot Weisswein bitteThe menu pleaseDie Speisekarte bitteIs there a local speciality Gibt es eine Spezialit t aus dieser Gegend I m VegetarianIch bin VegetarierIt was deliciousEs war hervorragendThe bill pleaseDie Rechnung bitteI have a headacheIch habe KopfschmerzenI have a sore throatIch habe HalsschmerzenMy stomach hurtsIch habe MagenschmerzenI m allergic toIch bin allergisch gegenI need a doctor who speaks EnglishGibt es einen Arzt der Englisch spricht Where is the nearest COVID 19 test centre Wo ist das n chste COVID 19 Testzentrum Virtual participation What s included Access to all the livestreamed talks Video library of the recorded talks during and after the event Facility to submit questions Please note that only on site participants are able to submit abstracts and participate in the poster sessions Event platform We are using an event platform for this conference More information about the platform will be shared ahead of the conference Guidelines Do not broadcast the conference to unregistered participants You are encouraged to tweet and post about the event Tweet unless the speaker specifically says otherwise but be mindful of unpublished data Please do not capture transmit or redistribute data presented at the meeting Additional information can be found in our Code of Conduct Health and well being It is important to stay healthy and move around especially when you are attending an event virtually We have put together a few coffee break stretches and yoga videos in the conference platform for you to enjoy during the event How to ask questions Please use the Q A function in the event platform If you have any other questions you can go to the Help Desk in the event platform Click on more on the top menu and click Help Desk Time zone The programme is planned based on the Europe Berlin time zone unless otherwise stated Please take your time zone into consideration when planning your attendance Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for participants page COVID 19 related questions COVID 19 information for on site events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Media partners EMBO reports an EMBO Press journal International Union of Biochemistry and Molecular Biology Bio Essays a Wiley Online Library Advanced Biology a Wiley Online Library Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information on sponsoring possibilities If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9 Leaderboard 728 90...

Hiroki Asari, Martha Bickford, Carl Petersen, Santiago Rompani

EMBO Workshop

EMBL Heidelberg, Virtual

23 November - 24 November 2023

Exploring EMBL-EBI sequence analysis tools and managing bioinformatics workflows

Edit

November 23, 2023 00:002023CourseVirtual

Description The European Bioinformatics Institute EMBL EBI offers a wide range of bioinformatics sequence analysis applications for free through web and programmatic access This two day course is designed to provide a comprehensive overview of sequence analysis tools and how to use the workflows effectively covering hands on exercises and demonstrations throughout The first day focuses on learning about the types of sequence analysis tools and how to use different tools in your analysis There will be a focus on sequence alignment e g Clustal Omega EMBOSS sequence similarity search tools mainly on how to perform Blast against the UniProt databases and using InterProScan for protein functional analysis The second day focuses on alternative methods of accessing the tools and how they help enhance flexibility in sequence analysis using web service clients and managing workflows...

Ajay Mishra

Virtual

22 November 2023

Accessing single cell transcriptome data with the Human Cell Atlas Data Portal

Edit

November 22, 2023 15:302023WebinarVirtual

Description The Human Cell Atlas is an ambitious project that aims to map the transcriptome of all the cell types in the human body This effort relies on single cell data generated from hundreds of labs across the globe which will be combined together into one comprehensive reference atlas The Data Portal helps to coordinate the data produced and standardise the format of data and metadata to reduce the burden of the integration efforts In this webinar we will provide an overview of data generation for HCA and how the data is curated for the Data Portal We will demonstrate how to navigate the Data Portal to find data that can be used for integration or as controls for your studies how to access the data and how to find the latest data from the integration efforts...

Virtual

20 November - 22 November 2023

25th EMBL PhD Symposium

Edit

November 20, 2023 00:002023ConferenceEMBL Heidelberg

Description If you are not redirected automatically please go to PhD Symposium website...

2023 EMBL PhD Symposium Organising Committee

EMBL Conference

EMBL Heidelberg

20 November - 24 November 2023

Genome bioinformatics: from short- to long-read sequencing

Edit

November 20, 2023 00:002023CourseEMBL-EBI

Description A guide to the technology analysis workflows tools and resources for next generation sequencing data analysis This course will provide insights and training into how biological knowledge can be derived from genomics experiments and explain different approaches in analysing such data The main focus will be on introducing sequence informatics re sequencing differences between short and long read sequencing and variant calling during the analysis of higher eukaryotes with an emphasis on human genetic research Throughout the week more advanced topics will introduce the creation of pipelines automation and the scaling up of analysis experiments Practical sessions will be run on datasets prepared by the trainers not on personal research data Participants will learn how to process these training datasets and to apply appropriate statistical methods in their analyses...

Sophie Spencer

EMBL-EBI

16 November 2023

Programmatic access to UniProt using Python

Edit

November 16, 2023 15:302023WebinarVirtual

Virtual

Edit

November 12, 2023 00:002023Public EventEMBL-EBI

Description Overview Overview 31st Protein Structure Determination in Industry PSDI meeting On behalf of the executive committee we are delighted to invite you to the 31st Protein Structure Determination in Industry Meeting which will be held at the Wellcome Genome Campus Hinxton Cambridge between November 12 14 2023 This year s PSDI meeting is organised jointly by EMBL EBI and GSK supported by Hg3 Conferences For the latest details on the Programme Abstracts Registration details Accommodation Exhibition Venue please visit the dedicated conference microsite If you have any queries regarding the upcoming PSDI 2023 Conference then please do not hesitate to contact Hg3 Conferences By email events hg3 co uk By phone 44 0 1423 529333...

EMBL-EBI

8 November 2023

Exploring protein families and domains using InterPro

Edit

November 08, 2023 15:302023WebinarVirtual

Description InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites using predictive models provided by 13 different databases This webinar will take you through the different ways to search the InterPro website and its API to identify protein families and domains We will explore different use cases including how to use the InterPro sequence search functionality to identify the protein family membership the different domains and potentially the protein function of unknown proteins We will also explain how InterPro can be used to identify new protein domains using AlphaFold structure predictions...

Virtual

8 November - 11 November 2023

The mobile genome: genetic and physiological impacts of transposable elements

Edit

November 08, 2023 00:002023ConferenceEMBL Heidelberg, Virtual

Description OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Please see EMBL s COVID 19 safety recommendations if attending the on site event Conference overview This conference assembles world leading experts from diverse fields including genomics epigenetics structural biology developmental biology immunology cancer biology and neurobiology to discuss the broad impacts of transposable elements TEs on organismal biology The meeting provides a venue for cross disciplinary discussions with the goal of catalysing inter disciplinary collaborations to address emerging questions in these scientific fields Although often disparaged as junk DNA it is now undeniable that TE activity has significantly shaped the structure and function of all genomes ranging from bacteria to humans TEs are major drivers of genetic diversity and contribute to human disease Remarkably TE derived sequences are also often co opted by the host to play important roles in gene expression early development immunity neuronal diversification and perhaps aging Session topics Genomics and evolution Transposon regulation Transposition mechanisms Physiological impacts I Physiological impacts II Speakers Keynote speakers John Moran University of Michigan USA Anne Ferguson Smith University of Cambridge UK Speakers Joan Barau Institute of Molecular Biology Germany Jef Boeke NYU Grossman School of Medicine USA Virtual speaker Miguel Branco Queen Mary University of London UK Alejandro Burga Institute of Molecular Biotechnology Austria Daniel Croll University of Neuch tel Switzerland Ang lique Deleris Institute of Integrative Biology of the Cell I2BC France Sandra Duharcourt Institut Jacques Monod France Geoff Faulkner The University of Queensland Australia Yukiko Yamashita Massachusetts Institute of Technology USA Cl ment Gilbert Universit Paris Saclay France Vera Gorbunova University of Rochester USA Virtual speaker Michael Imbeault University of Cambridge UK Johan Jakobsson Lund University Sweden Claudia K hler Max Planck Institute of Molecular Plant Physiology Germany Virtual speaker Eric Miska University of Cambridge UK Tomoichiro Miyoshi Kyoto University Japan Coleen Murphy Princeton University USA Virtual speaker Jos Penad s Imperial College London UK Joseph Peters Cornell University USA Femi Olorunniji Liverpool John Moores University UK Sandra Richardson Mater Research Institute Australia Martin Taylor Harvard Medical School USA Phillip Zamore UMass Chan Medical School USA Scientific organisers D borah Bourc his Institut Curie France Julius Brennecke Institute of Molecular Biotechnology Austria Jose L Garcia Perez The University of Edinburgh UK Virtual Susan Wessler University of California Riverside USA Virtual Conference organiser Diah Yulianti EMBL Heidelberg Germany Programme Got something to say Tweet it EMBOMobileGenome For registered participants recorded talks will be accessible on demand for 2 weeks after the end of the event unless indicated otherwise Day 1 Wednesday 8 November 2023 Time Europe Berlin Speaker 11 00 12 45Registration and light lunchShuttle Bus schedule12 45 13 00Opening remarksScientific organisers D borah Bourc his Institute Curie France and Julius Brennecke Institute of Molecular Biotechnology Austria13 00 18 15Session 1 Genomics and evolutionChaired by Julius Fabian Brennecke Institute of Molecular Biotechnology AustriaMarianne Yoth Aarhus University France13 00 13 30Escapee L1s promote parvalbumin interneuron developmentGeoff Faulkner University of Queensland Australia13 30 13 45Evolution of gene regulation by species specific transposable elements in primatesMari Ohnuki Kyoto University Japan13 45 14 00Protein domains from multigene families recurrently associate with domains derived from transposable elements and virusesMiguel Vasconcelos Almeida University of Cambridge UK14 00 14 30A Devil s Bargain with TEs for crop pathogen adaptationDaniel Croll University of Neuchatel Switzerland14 30 15 00Locus resolution analysis of L1 regulation and retrotransposition potential in mouse embryonic developmentSandra Richardson Mater Institute Australia15 00 15 30The role of the Cer1 transposon in horizontal transfer of transgenerational memoryColeen Murphy Princeton University USAVirtual talk15 30 16 00Coffee break and Meet the speakers withGeoff Faulkner Daniel Croll and Sandra Richardson16 00 16 15Exploring the contribution of transposable elements to the evolution of salamander developmental and regenerative programsDiego Rodriguez Terrones Research Institute of Molecular Pathology Austria16 15 16 30The silent architects of yeast genomeAleksandras Konovalovas Vilnius University Life Sciences Centre Institute of Biosciences Lithuania16 30 16 45The transcriptional repertoire of transposable elements during mammalian preimplantation developmentMarlies Oomen Helmholtz Zentrum Munich GermanyNot available on demand16 45 17 15Horizontal transfer of transposable elements in animalsCl ment Gilbert Paris Saclay University France17 15 18 15Keynote speaker 1 The genetics of epigenetic variation at transposable elements Anne Ferguson Smith University of Cambridge UK18 15 19 45Dinner19 45 21 15Science pub quiz optional EMBL Canteen19 45 21 45After dinner drinks optional ATC Rooftop Lounge Day 2 Thursday 9 November 2023 Time Europe Berlin Speaker 09 00 20 00Session 2 Transposon regulationChaired by D borah Bourc his Institut Curie FranceJuliane Glaser Max Planck Institute for Molecular Genetics Germany09 00 09 30Architects of genomic harmony KRAB zinc finger proteins expand the domestication potential of mobile elementsMichael Imbeault University of Cambridge UK09 30 09 45Novel actors involved in chromatin associated TE control in embryonic stem cellsEmeline Roger Institut Curie FranceNot available on demand09 45 10 15H3K27me3 recruitment at Transposable Elements in ArabidopsisAng lique Deleris I2BC Gif sur Yvette France10 15 10 30Comprehensive investigation of de novo insertions in piRNA clusters reveals dual functions of Panoramix in the piRNA pathwayYicheng Luo California Institute of Technology USA10 30 11 00Coffee break and Meet the speakers withAnne Ferguson Smith and Michael Imbeault11 00 11 30Transposable elements drive hybrid incompatibility in plantsClaudia K hler Max Planck Institute of Molecular Plant Physiology GermanyVirtual talk11 30 12 00Regulation of TEs in the mammalian germlineJoan Barau IMB Mainz Germany12 00 12 15Young hot L1s in the human genome evade the host restriction factor TEX19Ricky Padilla Del Valle University of Washington USANot available on demand12 15 12 30Flash Talks 1 odd numbers 53 54 101 141 15312 30 14 00Lunch and Meet the speakers withJoan Barau14 00 16 00Poster session 1 odd numbers 16 00 16 30Catalytic and non catalytic functions of PRC2 in the control of transposable elements in ParameciumSandra Duharcourt Institut Jacques Monod France16 30 16 45Recurrent molecular adaptation revealed by systematic cross species protein interaction analyses of the Drosophila piRNA pathwaySebastian Riedelbauch Aarhus University Denmark16 45 17 00A direct protein protein interaction network of cytoplasmic Drosophila piRNA pathway factorsMandy Jeske Heidelberg University Germany17 00 17 30PiRNA mediated TE control in mammalsPhilip Zamore University of Massachusetts Medical School USA17 30 17 45A co opted retroviral capsid defines a rapidly evolving architectural protein family that binds to transposable elementsWayo Matsushima cole Polytechnique F d rale de Lausanne EPFL Switzerland17 45 18 00Flash Talks 2 even numbers 92 118 162 16418 00 18 30Coffee break and Meet the speakers withSandra Duharcourt and Philip Zamore 18 30 19 00Genetics of cheating of geneticsYukiko Yamashita MIT Cambridge USA19 00 19 30The role of L1 elements in promoting agingVera Gorbunova University of Rochester USAVirtual talk19 30 19 45Transposon silencing in duckweeds lessons from non model organismsArturo Mari Ordonez Gregor Mendel Institute of Molecular Plant Biology Austria19 45 20 00Structural and biochemical insights on the role of HUSH component MPP8 in transposon regulationYorgo Modis University of Cambridge UK20 00 21 30Dinner21 00 22 30After dinner drinks Day 3 Friday 10 November 2023 Time Europe Berlin Speaker 09 00 14 00Session 3 Transposition mechanismsChaired by Orsolya Barabas University of Geneva SwitzerlandTomoichiro Miyoshi RIKEN Japan09 00 09 30Redefining mobility in bacterial geneticsJose Penad s Imperial College London UK09 30 09 45Structure function analysis of mammalian tRNA derived SINEsEmily Koch University of Michigan USA09 45 10 15A network of interferon stimulated genes inhibits human LINE 1 retrotranspositionTomoichiro Miyoshi RIKEN Japan10 15 10 30Extrachromosomal circular DNA reveals helitron activity in wheatEtienne Bucher Agroscope Switzerland10 30 11 00Coffee break and Meet the speakers withYukiko Yamashita Jose Penad s and Tomoichiro Miyoshi11 00 11 30Regulation of site specific recombination by serine integrasesFemi Olorunniji Liverpool John Moores University UK11 30 11 45From retroelements to retroviruses the evolutionary plasticity of reverse transcribing RNA virusesHaoming Zhai University of Cambridge UK11 45 12 15Diversity of target selection systems with Tn7 like elements from CRISPR guided transposons to bacterial telomere elementsJoseph Peters Cornell University USA12 15 12 30The genetic and environmental basis of heritable transposition in Arabidopsis thalianaMireia Bueno Merino IPS2 Paris Saclay University France12 30 12 45Genomic integration of SARS CoV 2 sequences in virus infected and viral RNA transfected human cells and infection of bat iPS cells with virusRudolf Jaenisch Whitehead Institute USA12 45 14 00Lunch and Meet the speakers withFemi Olorunniji and Joseph Peters14 00 16 30Session 4 Physiological impactsChaired by John Moran University of Michigan USAStephanie Workman Mater Research Institute Australia14 00 14 30Structural analysis and inhibition of human LINE 1 ORF2 protein reveals novel adaptations and functionsMartin Taylor Harvard Medical School USA14 30 15 00Giant virus like transposons mediate widespread horizontal gene transfer in nematodesAlejandro Burga IMBA Austria15 00 15 30Coffee break and Meet the speakers withMartin Taylor and Alejandro Burga15 30 16 30Keynote speaker 2 Studies of a human retrotransposable elementJohn Moran University of Michigan Ann Arbor USA16 30 17 30Panel Discussion on emerging topics in TE biologyNot available on demand17 30 19 30Poster session 2 even numbers 19 30 21 00Conference dinner21 00 00 00Conference party Day 4 Saturday 11 November 2023 Time Europe Berlin Speaker 09 00 13 15 Session 4 Physiological impacts continued Chaired by John Moran University of Michigan USAStephanie Workman Mater Research Institute Australia 09 00 09 15Co opted endogenous retrovirus governed Pregnancy Specific Glycoprotein 9 PSG9 locus coordinates trophoblast differentiation in human placentationZsuzsanna Izsvak Max Delbr ck Center Germany09 15 09 45Species specific regulation of trophoblast gene expression by endogenous retroviruses Miguel Branco Queen Mary University of London UKNot available on demand09 45 10 00Helitron derived repeat structures regulate transgenerational inheritance in C elegansFaisal Alkhaldi King Abdullah University of Science and Technology KAUST Saudi Arabia10 00 10 30Transposable elements and human brain disordersJohan Jakobsson Lund University Sweden10 30 10 45Reverse transcriptase related genes at the intersection of environmental stress responsesIrina Arkhipova Marine Biological Laboratory USANot available on demand10 45 11 00Somatic LINE retrotransposition in motorneurons has functional consequencesThomas Widmann FIBAO Fundaci n de Investigaci n Biosanitaria GENYO Centre for Genomics and Oncological Research Spain11 00 11 30Coffee break and Meet the speakers withJohn Moran Miguel Branco Johan Jakobsson and Eric Miska11 30 11 45Retroviral like particles inducing cell death drive a limb developmental malformationJuliane Glaser Max Planck Institute for Molecular Genetics Germany11 45 12 15Great GEMMs reveal dramatic human phenotypes conferred by intronic retrotransposon insertionsJef Boeke NYU Grossman School of Medicine USAVirtual talkNot available on demand12 15 12 30The Drosophila retrotransposable element Copia regulates larval neuromuscular junction physiologyPeter M Angale University of Massachusetts Chan Medical School USA12 30 12 45Endogenous retroviruses wrestle with epigenetic surveillance to drive host pathophysiologyYejing Ge MD Anderson Cancer Center USANot available on demand12 45 13 15piRNA dynamics in mammalian genomesEric Miska University of Cambridge UK13 15 13 30Closing remarks13 30 14 00Packed lunch and departure14 00Shuttle bus to Frankfurt airport tickets 30 Practical information Registration fees and abstract submission On site registration fees include admission conference materials COVID 19 safety measures meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Virtual registration fees include access to all of the talks livestreamed and on demand and facility to submit questions On site Academia 450On site PhD Student 350On site Industry 750Virtual Academia 200Virtual PhD Student 150Virtual Industry 250 A letter to support your visa application will be issued on request once payment of the registration fee is confirmed We recommend that you book your visa appointment as soon as possible to avoid any delay with your visa application Accredited journalists may be eligible to register for complimentary press registration Registrants may be required to provide accreditation or equivalent proof of press membership after registration Please contact Diah Yulianti for more information Please note that we do not offer complimentary registrations for editors of scientific journals Confirmation and payment Registration will be on a first come first served basis Your place can only be confirmed after payment of the registration fee If you are added to our waiting list please consider taking advantage of our offerings to participate virtually On site participants Types of payments accepted are international bank transfers and credit card payments Virtual participants We are only able to accept card payments In exceptional cases we can accept bank transfers Please contact events embl de for details Abstract submission Only participants registering to attend the on site event are eligible to submit an abstract Abstracts will not be accepted from virtual participants After registration you can submit your abstract via a separate link that will be provided in the email confirmation Alternatively you can access the link on the confirmation page directly after registering The same login credentials are used for both processes Please note Abstract body The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised Title The title should not exceed 20 words Only the first word of the title should start with a capital letter and the rest should be lowercase Authors and affiliations Please fill in the author s details as requested in the online form The compulsory fields are First Name Last Name Organisation Name Affiliation or Company Country and Email Kindly mark only one author in the role of First Author and please don t forget to indicate who will be the Presenter Please enter your co authors correctly via the system by adding accounts together with their organisation institute Do not copy paste them into the body of the abstract text as they will not be indexed in the abstract book Presentation types When submitting your abstract you can apply for an oral or poster presentation A selection process will take place with the results announced 2 3 weeks after the abstract submission deadline For detailed instructions on how to submit a conference abstract follow the instructions provided in this video Please check our FAQs pages for further information on how to submit an abstract Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of both registration fee waivers and travel grants These are available for on site participants at EMBL Conferences and EMBO EMBL Symposia and for on site and virtual participants at EMBO Workshops We are currently working on securing funding for all virtual participants and ask that you please apply for financial assistance for both on site and virtual participation Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course or conference Travel grant The travel grant will cover the cost of travel to an on site event airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from within Europe up to 1000 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from outside Europe up to 500 for any participant travelling to an EMBO Workshop up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Workshop up to 700 for any participant working in Croatia Czech Republic Estonia Greece Hungary Italy Lithuania Luxembourg Poland Slovenia and Turkey travelling to an EMBO Workshop Registration fees are only covered for EMBO Workshops The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant EMBO Workshops only For EMBO Workshop participants with children there is the possibility to apply for a childcare grant to offset child care costs incurred by participants or speakers when participating at a conference Eligible costs include fees for a baby sitter or child care facility travel costs for a caregiver or travel costs for taking the child to the meeting etc Please note that priority will be given to early stage researchers A maximum amount of 500 can be awarded per participant applying for an EMBO childcare grant In order to apply for this grant for EMBO Workshops you must be registered by the abstract submission deadline Application On site participants You may apply for financial assistance when submitting your abstract In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Virtual participants If you are attending virtually you can apply for financial assistance in the submission portal by the abstract deadline Read the instructions on how to apply for financial assistance Only submissions for financial assistance will be accepted Presentation abstracts cannot be submitted here and will be declined In your application you will be asked to summarise your current work answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Selection The scientific organisers will select the recipients of all financial assistance during the abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details View our list of external funding opportunities and information on attending a conference as an event reporter For further information about financial assistance please refer to the FAQ page Accommodation and shuttles Accommodation is not included in the conference registration fee Conference shuttle buses Conference shuttle buses are free of charge for participants and depart from designated bus stops near the hotels to EMBL and back mornings and evenings The bus stops for this conference are Kurf rsten Anlage Opposite Main Train Station Hotel Premier Kurf rsten Anlage 23 Leonardo Hotel Bergheimer Str Neckarmuenzplatz Peterskirche ISG Hotel Here are the shuttle bus times for this conference View Conference shuttle bus stops and hotels in a larger map Please note that not every bus stop will be used for every event Further details Address EMBL Meyerhofstra e 1 69117 Heidelberg Germany For further information on getting to EMBL Heidelberg visit Public Transportation to the Venue For information about accommodation and local transportation please refer to the FAQ page On site information Catering All meals and coffee breaks are included in the registration fee Our catering staff will prepare a wide variety of vegetarian meals meat and fish dishes soups pasta fresh fruit and vegetables as well as a variety of desserts Please wear your badge at all times when serving yourself No food or drinks are allowed in the auditorium Charging lockers There are lockers available next to the stairs leading down into the Auditorium You will find some of those equipped with sockets to charge your smartphone tablet etc Electricity and charging station In most places the electricity is 220 volts AC 50 cycles An adaptor and a plug that fits the German socket may be needed for your appliances laptop i e American Japanese etc A USB charging station for electronic devices is available at the registration desk EMBL merchandise If you are interested in purchasing an EMBL souvenir products presented in the glass display in the registration area please ask at the registration desk for more information Health and safety notes Please read EMBL s COVID 19 safety policy for on site events Do not smoke in any EMBL building Eating and drinking is prohibited in the Auditorium and all laboratories Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required The first aid room is located next to the ATC Registration Desk room 10 205 Dial the Emergency number 222 from any EMBL internal phone only Where is the accident What happened How many injured Emergency number 06221 387 7821 from mobile phones Please report all accidents to the conference officer at the registration desk In case of fire Press the nearest fire alarm button or the Emergency number 222 from any internal phone A loud fire alarm will go off if an evacuation is required On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting points Do not use the lifts Beyond first aid Please remember to bring your own medication if needed to the conference Note that the next pharmacy is a 4 minute drive from the EMBL but for many medications you will be required to see a doctor to get a prescription Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg In any case the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary Internet Wi Fi is available on campus Log in using the EMBL Events network and the event hashtag as the password The eduroam network secure worldwide roaming access service developed for the international research and education community is also available Lost and found Lost and Found are kept at the registration desk until the end of the conference Luggage There are lockers available on site to store your luggage which require a 2 EURO coin to operate There is another luggage room on level E0 which is free to use but remains unlocked during the conference Nursing room There is a nursing room available in the ATC Rooftop Lounge on level A29 Photography During the conference an EMBL Photographer may be taking photos If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Printing We can help print your boarding pass train ticket Please send it to events embl de and collect your print outs at the registration desk Room for prayer yoga and meditation There is a room for prayer meditation and yoga located on level E0 behind the Auditorium Please be respectful of other participants using the room Sightseeing A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing Travel to and from the venue During the event we provide conference shuttle buses to and from EMBL In addition there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time Information on the conference shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page Useful German expressions HelloHalloGoodbyeTsch ssGood morningGuten MorgenGood afternoonGuten TagGood eveningGuten AbendGood nightGute NachtI m sorryEs tut mir leidExcuse me Entschuldigen SieHow are you Wie geht s I m fine thanks And you Mir geht es gut danke und dir Ihnen What is your nameWie heisst du Wie heissen Sie My name isIch heisseDo you speak EnglishSprechen Sie Englisch I don t understandIch verstehe nichtPlease speak more slowlyK nnen Sie bitte langsamer sprechenThank youDankesch nWhere is the toilet Wo ist die Toilette Please call me a taxiBitte rufen Sie mir ein TaxiHow do I get to Wie komme ich zum zur A beer two beers pleaseEin Bier zwei Bier bitteA glass of red white wine pleaseEin Glas Rot Weisswein bitteThe menu pleaseDie Speisekarte bitteIs there a local speciality Gibt es eine Spezialit t aus dieser Gegend I m VegetarianIch bin VegetarierIt was deliciousEs war hervorragendThe bill pleaseDie Rechnung bitteI have a headacheIch habe KopfschmerzenI have a sore throatIch habe HalsschmerzenMy stomach hurtsIch habe MagenschmerzenI m allergic toIch bin allergisch gegenI need a doctor who speaks EnglishGibt es einen Arzt der Englisch spricht Virtual Participation What s included Access to all the livestreamed talks Video library of the recorded talks during and after the event Facility to submit questions Please note that only on site participants are able to submit abstracts and participate in the poster sessions Event platform We are using an event platform for this conference More information about the platform will be shared ahead of the conference Guidelines Do not broadcast the conference to unregistered participants You are encouraged to tweet and post about the event Tweet unless the speaker specifically says otherwise but be mindful of unpublished data Please do not capture transmit or redistribute data presented at the meeting Additional information can be found in our Code of Conduct Health and well being It is important to stay healthy and move around especially when you are attending an event virtually We have put together a few coffee break stretches and yoga videos in the conference platform for you to enjoy during the event How to ask questions Please use the Q A function in the event platform If you have any other questions you can go to the Help Desk in the event platform Click on more on the top menu and click Help Desk Time zone The programme is planned based on the Europe Berlin time zone unless otherwise stated Please take your time zone into consideration when planning your attendance Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page COVID 19 related questions COVID 19 information for on site events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Media partners EMBO reports an EMBO Press journal International Union of Biochemistry and Molecular Biology FEBS Open Bio a FEBS Press journal Bio Essays a Wiley Online Library Advanced Biology a Wiley Online Library Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information on sponsoring possibilities If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9 Leaderboard 728 90...

Déborah Bourc’his, Julius Brennecke, Jose L. Garcia-Perez, Susan Wessler

EMBO Workshop

EMBL Heidelberg, Virtual

7 November 2023

Multiscale model of the different modes of invasion: a PhysiBoSS application

Edit

November 07, 2023 15:002023WebinarVirtual

Description The tumour microenvironment encompasses many different cell types including cancer cells stromal cells immune cells and the extracellular matrix ECM that interact and collectively influence cancer progression and treatment outcomes Recently computational mathematical models have been proved efficient in testing hypotheses and giving insights about tumour microenvironment functionalities Among those hybrid multiscale models combine different techniques that simulate both inter and intra cellular interactions In this context we present a 3D model of cancer cell invasion aiming to study the different modes of cell migration through the extracellular matrix and to predict means to block it by considering spatial information molecules diffusion and intracellular regulation The model was constructed using PhysiBoSS a multiscale framework which combines agent based modelling and continuous time Markov processes applied on Boolean network models Our multiscale model successfully reproduces single and collective migration processes reported in published experiments on cell invasion These experiments include various aspects such as the role of p63 expression in regulating MT1 MMP the spatio temporal activation of SRC triggering collective migration and the influence of different collagen densities on invasion modes In silico experiments can be performed to suggest potential targets capable of inhibiting highly invasive tumour phenotypes About the speakerMarco Ruscone is a PhD student in the Computation Systems Biology of Cancer group at Institut Curie Paris He started his academic career in Turin Italy where he pursued his bachelor degree in Physics and master degree in Physics of Complex Systems for the Biology at Universit degli Studi di Torino Currently his work focuses on developing multiscale models of cancer using a mixed approach of agent based modelling and simulation on Boolean networks...

Marco Ruscone

Virtual

7 November 2023

How to make your research open with Europe PMC

Edit

November 07, 2023 10:002023WebinarVirtual

Description Europe PMC is an open global database of life science publications and preprints hosted by European Bioinformatics Institute EMBL EBI Europe PMC is endorsed and supported by a group of international science funders including Wellcome World Health Organisation European Research Council and many others as their repository of choice The Europe PMC funders expect research outputs arising from research they support to be made freely and readily available In this webinar we will explain how researchers can make their research open using Europe PMC and cover the benefits of including publications and preprints in Europe PMC for authors and readers We will provide guidance on open access policies of Europe PMC funders and demonstrate how to include research publications in Europe PMC and PubMed Central USA...

Virtual

7 November - 9 November 2023

Managing a bioinformatics core facility

Edit

November 07, 2023 00:002023CourseEMBL-EBI

Description This knowledge exchange workshop is an opportunity for managers of bioinformatics core facilities to learn from EMBL EBI s service teams and from each other These facilities play an essential role in enabling research in the molecular life sciences The landscape is constantly evolving as new research tools emerge as experiments become increasingly data intensive and as their clients experimental researchers become more exposed to the power of data driven biology This course will allow participants to share experiences discuss challenges and solutions that they face and plan ways to cope with the ever changing demands raised by the molecular life science field It will include sessions to learn from bioinformatics service providers hear how others have tackled common problems and work together to design core services resource them and measure their impact A limited number or travel bursaries are available Please see the Additional information tab for conditions...

Juanita Riveros

EMBL-EBI

6 November - 9 November 2023

Preparation of genomics libraries for an emerging next-gen sequencing platform

Edit

November 06, 2023 00:002023CourseEMBL Heidelberg

Description OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview Course overview This course will focus on the latest state of the art sequencing platform technology and novel library preparation protocols We will start with experimental design focusing on the hands on library preparation including best practices standards and potential pitfalls concluding with sequencing of libraries bioinformatic evaluation best practice For this purpose we will use for the first time ever in the settings of the practical course the cutting edge sequencing platform AVITI https www elementbiosciences com products aviti which was developed by Element Biosciences and is currently entering the next gen sequencing NGS field An evaluation of the technology in conjunction with the newly developed library preparation reagents by New England Biolabs NEB will be important for the scientific community and course participants to assist their decision if to adopt the new sequencing technology The course will cover a complete workflow such as library preparation and sequencing The course participants will also learn about its tips and tricks and will also use bioinformatics tools required for data processing quality control and initial data analysis Beside the practical exercises lectures and discussion sessions the course will offer the opportunity to learn more about transferring the knowledge gained during the course to the home institute of the participants as well as the implementation of this new technology into the environment of genomics core facilities During the course participants will prepare two types of NGS libraries gDNA Seq and mRNA Seq We offer the opportunity to provide a maximum of 2 samples Those samples must be shipped to Heidelberg prior to the course and must meet quality criteria of EMBL GeneCore Generated libraries will be used for shallow sequencing Audience This course is directed towards wet lab molecular biologists scientists and technicians who want to assess and use the AVITI technology A focus will be on applicants from member states and their genomics core facilities This audience can best disseminate the knowledge gained during the course and serve scientists at their home institutes Modules resources Presentation of the latest state of the art sequencing technology Element Biosciences the AVITI system Hands on training on genomic library preparation with upcoming state of the art reagents Setting up an AVITI sequencing run Basics in data handling and analysis Learning outcomes The NGS field is entering a new phase of sequencing platforms available to the community and for their various applications One crucial eplatform is the Aviti sytem by Element Bioscinces During the course its participants will be exposed to the cutting edge sequencing technology learn to apply novel NEBNext NGS library preparation reagents and protocols learn about the benefits and bottlenecks of different systems be provided with guidance on the implementation of sequencing technologies into the core facility environment What past participants say about this course I truly recommend this course to anyone interested in RNASeq We were pushed to go below the limits of RNA input to construct libraries and it was an exciting challenge The spirit of science go beyond our limits was present through all of the course The knowledge sharing environment with all the participants trainers and speakers made this one of the best courses I have ever attended Anna Sofia Varanda University of Aveiro Portugal Speakers Speakers trainers and staff Stefaan Derveaux VIB Nucleomics Core Belgium Lim De Swert VIB Nucleomics Core Belgium Max Fritsch New England Biolabs Inc UK Samina Kaufmann Agilent Technologies Germany Jonathan Landry EMBL Heidelberg Germany Chris Mason Weill Cornell Medicine USA Virtual Speaker Pingfang Liu New England Biolabs USA Chris Mason Weill Cornell Medicine USA Virtual Speaker Matthias Meister Agilent Technologies The Netherlands Mireia Osuna Lopez EMBL Heidelberg Germany Hilal Ozgur EMBL Heidelberg Germany Michael Petridis New England Biolabs Inc USA Jan Provaznik EMBL Heidelberg Germany Tobias Rausch EMBL Heidelberg Germany Jessica Sutter EMBL Heidelberg Germany Laura Villacorta EMBL Heidelberg Germany Daphne Welter EMBL Heidelberg Germany Scientific organisers John Baeten Element Biosciences The Netherlands Vladimir Benes EMBL Heidelberg Germany Bj rn Textor New England Biolabs Germany Pingfang Liu New England Biolabs USA Laura Villacorta EMBL Heidelberg Germany Course organisers Luana Ribeiro EMBL Heidelberg Germany Catherine Casas EMBL Heidelberg Germany Irena Provaznikova Training Lab Technician EMBL Heidelberg Germany Programme Got something to say Tweet it EMBLSeqLibPrep Some speakers may need to join virtually to give their lecture or Q A and the programme is subject to change Day 1 Monday 6 November 2023 Time Europe Berlin SessionLocation12 40Bus from ISG Hotel to EMBLHotel Entrance13 15 13 30Welcome of participants registrationFlex Lab A B13 30 14 00EMBL introduction house notes and lab safetyVladimir Benes EMBL Heidelberg GermanyBjoern Textor New England Biolabs USA John Baeten Element Biosciences The Netherlands Laura Villacorta EMBL Heidelberg GermanyLuana Ribeiro EMBL Heidelberg GermanyIrena Provaznikova EMBL Heidelberg GermanyFlex Lab A B14 00 14 30Lecture 1 Get familiar with the lab and introduction into the NEBNext Ultra II FS DNA workflow for Element BiosciencesPingfang Liu New England Biolabs USAVladimir Benes EMBL Heidelberg GermanyFlex Lab A B14 30 14 45Practical session Fragmentation End PrepPingfang Liu New England Biolabs USAMichael Petridis New England Biolabs USAMax Fritsch New England Biolabs USA Lim de Swert VIB Nucleomics Core Belgium Hilal Ozgur EMBL Heidelberg Germany Daphne Welter EMBL Heidelberg GermanyTraining Lab B14 45 16 00Icebreaking activity Introduction round each participant 2 slides Flex Lab A B16 00 17 45Practical session Adaptor ligation Cleanup of adaptor ligated DNA size selection of adaptor ligated DNA and setup enrichment PCRPingfang Liu New England Biolabs USAMichael Petridis New England Biolabs USAMax Fritsch New England Biolabs USA Lim de Swert VIB Nucleomics Core Belgium Hilal Ozgur EMBL Heidelberg Germany Daphne Welter EMBL Heidelberg GermanyTraining Lab B17 45 18 30Lecture 2 NEBNext protocol discussion and performance on the Aviti systemPingfang Liu New England Biolabs USAVladimir Benes EMBL Heidelberg GermanyFlex Lab A B18 30 19 30Practical session Clean UpPingfang Liu New England Biolabs USAMichael Petridis New England Biolabs USAMax Fritsch New England Biolabs USA Lim de Swert VIB Nucleomics Core Belgium Hilal Ozgur EMBL Heidelberg Germany Daphne Welter EMBL Heidelberg GermanyTraining Lab B19 30 20 30Dinner at EMBLEMBL Canteen20 30Departure to hotelEMBL Bus Stop Day 2 Tuesday 7 November 2023 Time Europe Berlin SessionLocation08 40Bus from ISG Hotel to EMBLHotel entrance09 00 09 10Overview of the dayFlex Lab A B09 10 10 00Lecture 3 The Aviti platform at the VIB Nucleomics Core from implementation to routine usage Stefaan Derveaux VIB Nucleomics BelgiumFlex Lab A B10 00 10 15Introduction into RNA library preparation protocolPingfang Liu New England Biolabs USAVladimir Benes EMBL Heidelberg GermanyFlex Lab A B10 15 12 30Practical session polyA First Second Strand SynthesisPingfang Liu New England Biolabs USAMichael Petridis New England Biolabs USAMax Fritsch New England Biolabs USALim de Swert VIB Nucleomics Core Belgium Laura Villacorta EMBL Heidelberg Germany Mireia Osuna Lopez EMBL Heidelberg GermanyTraining Lab B12 30 13 30LunchEMBL Canteen13 30 14 30Practical session cDNA continuesPingfang Liu New England Biolabs USAMichael Petridis New England Biolabs USAMax Fritsch New England Biolabs USALim de Swert VIB Nucleomics Core Belgium Laura Villacorta EMBL Heidelberg Germany Mireia Osuna Lopez EMBL Heidelberg GermanyTraining Lab B14 30 15 00Practical session Set Up of End Prep dA TailingPingfang Liu New England Biolabs USAMichael Petridis New England Biolabs USAMax Fritsch New England Biolabs USALim de Swert VIB Nucleomics Core Belgium Laura Villacorta EMBL Heidelberg Germany Mireia Osuna Lopez EMBL Heidelberg GermanyTraining Lab B15 00 16 30Practical session Ligation and Clean Up PCR Set UpPingfang Liu New England Biolabs USAMichael Petridis New England Biolabs USAMax Fritsch New England Biolabs USALim de Swert VIB Nucleomics Core Belgium Laura Villacorta EMBL Heidelberg Germany Mireia Osuna Lopez EMBL Heidelberg GermanyTraining Lab B16 30 17 30Lecture 4 Multi omic profiling methods for astronauts and spaceflight virtual Chris Mason Weill Cornell USAFlex Lab A B17 30 18 30Practical session Clean UpPingfang Liu New England Biolabs USAMichael Petridis New England Biolabs USAMax Fritsch New England Biolabs USALim de Swert VIB Nucleomics Core Belgium Laura Villacorta EMBL Heidelberg Germany Mireia Osuna Lopez EMBL Heidelberg GermanyTraining Lab B18 30 19 45Tips Tricks with concurrent Pizza DinnerATC Rooftop Lounge19 45Departure to HotelEMBL Bus Stop Day 3 Wednesday 8 November 2023 Time Europe Berlin SessionLocation08 40 Bus from ISG Hotel to EMBLHotel Entrance09 00 09 10Overview of the dayFlex Lab A B09 10 10 00Practical session Library QCPingfang Liu New England Biolabs USAMichael Petridis New England Biolabs USA Max Fritsch New England Biolabs USA Lim de Swert VIB Nucleomics Core Belgium Hilal Ozgur EMBL Heidelberg Germany Laura Villacorta EMBL Heidelberg Germany Daphne Welter EMBL Heidelberg Germany Mireia Osuna Lopez EMBL Heidelberg Germany Jessica Sutter EMBL Heidelberg GermanyTraining Lab B10 00 11 00Lecture 5 Library QC A perspective from Agilent TechnologiesSamina Kaufmann Agilent Technologies GermanyFlex Lab A B11 00 12 30Lecture 6 Aviti System by Element Biosciences John Baeten Element Biosciences The NetherlandsFlex Lab A B12 30 13 15LunchEMBL Canteen13 15 13 30Group Photo13 30 15 00Set up of the Aviti Sequencer Tour through GeneCore FacilityJohn Baeten Element Biosciences The NetherlandsVladimir Benes EMBL Heidelberg GermanyGeneCore Facility15 00 15 30Coffee Break15 30 17 00Lecture 7 Considerations on experimental design and NGS implementation the Core FacilityVladimir Benes EMBL Heidelberg GermanyFlex Lab A B17 00Bus Heidelberg downtown and sightseeingATC Entrance19 30Dinner Networking NEB sponsored Oskar Vinothek and Restaurant Day 4 Thursday 9 November 2023 Time Europe Berlin SessionLocation08 40 Bus from ISG Hotel to EMBL Hotel Entrance09 00 09 10Overview of the dayComputer Training Lab09 10 10 00Practical Lecture Introduction to NGS Data formats and QC Jan Provaznik EMBL Heidelberg GermanyJonathan Landry EMBL Heidelberg GermanyComputer Training Lab10 00 10 30Coffee break10 30 12 00Practical Lecture Review Generated Raw Data Element Cloud Solution John Beaten Element Biosciences The NetherlandsComputer Training Lab12 00 13 00Lunch EMBL Canteen13 00 14 30Practical session Light Intro to Genome Mapping Variant Calling Jan Provaznik EMBL Heidelberg GermanyJonathan Landry EMBL Heidelberg GermanyTobias Rausch EMBL Heidelberg GermanyComputer Training Lab14 30 15 00Feedback round and closing remarksFlex Lab A B15 30Bus to Heidelberg train station and city centerEMBL Bus Stop Practical information Registration fees and motivation letter The course is limited to 16 participants For selection purposes please note that your application will not be considered without a letter of motivation Registration fees include admission course materials meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Academia575 PhD Student575 Industry1100 A letter to support your visa application will be issued on request once payment of the registration fee is confirmed We recommend that you book your visa appointment as soon as possible to avoid any delay with your visa application Confirmation and payment The registration fee should be paid only after acceptance to the course The results will be announced approximately 2 3 weeks after the application deadline Motivation letter submission After you have logged in and successfully registered you will receive an email asking you to submit your motivation letter Click on the link provided and enter your motivation letter in the text box provided Alternatively you can submit your motivation letter by clicking on the link on the confirmation page directly after registering Instructions Include your relevant skills experience and qualifications showing why you would be suitable for the course Explain why you would like to attend including what you can contribute and how you think you will benefit from the course Please note The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised For detailed instructions please watch our video on how to submit a course motivation letter Further details For further information about registration and motivation letter submission please refer to the FAQ page Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of both registration fee waivers and travel grants Availability is limited to participants attending on site EMBL Courses and virtual or on site EMBO Practical Courses in Heidelberg and will be indicated during the motivation letter submission process Your place in the course is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course Travel grant The travel grant will cover the cost of travel airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Course within Europe up to 1000 for participants travelling to an EMBL Course from outside Europe up to 500 for any participant travelling to an EMBO Practical Course up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Practical Course up to 700 for any participant working in Croatia Czech Republic Estonia Greece Hungary Italy Lithuania Luxembourg Poland Slovenia and Turkey travelling to an EMBO Practical Course Registration fees are only covered for EMBO Practical Courses The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant EMBO Practical Courses only For EMBO Practical Course participants with children there is the possibility to apply for a childcare grant to offset child care costs incurred by participants or speakers when participating at a course Eligible costs include fees for a babysitter or child care facility travel costs for a caregiver or travel costs for taking the child to the meeting etc Please note that priority will be given to early stage researchers A maximum amount of 500 can be awarded per participant applying for an EMBO childcare grant Boehringer Ingelheim Fonds travel grant Applies to selected courses only Availability will be indicated during the motivation letter submission process This grant covers costs related to your attendance at the course registration travel and accommodation costs The grant is restricted to PhD students and postdocs who conduct basic biomedical research Whether you are eligible to apply for a travel grant depends on when you received your university entrance qualification e g Abitur A Levels High School Diploma Final State Examination for PhD and MD students as well as graduates the university entrance qualification must not have been obtained more than 11 years ago at the time of the envisaged course for postdocs the university entrance qualification must not have been obtained more than 13 years ago at the time of the envisaged course Application You may apply for financial assistance when submitting your motivation letter for courses In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application For the Boehringer Ingelheim Fonds Travel Grant there is a pre application question during the motivation letter submission process and if selected you will be requested to complete a standard form and documentation consisting of your travel expense estimation Selection The scientific organisers will select the recipients of all financial assistance during the motivation letter selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the course Selection is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details See our list of external funding opportunities and for further information about financial assistance please refer to the FAQ page Accommodation and shuttles Hotel Single rooms have been reserved for 5 nights 5 10 November 2023 at the ISG Hotel After the selection process selected participants should contact the hotel directly to make a booking booking code NEB23 01 We recommend that all course participants stay at the ISG Hotel which is the dedicated hotel for the course Local transport Shuttle buses will go from the ISG Hotel to EMBL and back mornings and evenings A bus schedule and location of the bus stops will be made available prior to the meeting Further details Address EMBL Heidelberg Meyerhofstra e 1 69117 Heidelberg GermanyFor further information on getting to EMBL Heidelberg visit our Travel Information page For enquiries about accommodation and local transportation please refer to the FAQ page On site information Catering All meals and coffee breaks are included in the registration fee Our catering staff will prepare a wide variety of vegetarian meals meat and fish dishes soups pasta fresh fruit and vegetables as well as a variety of desserts Please wear your badge at all times when serving yourself No food or drinks are allowed in the laboratories Electricity and charging station In most places the electricity is 220 volts AC 50 cycles An adaptor and a plug that fits the German socket may be needed for your appliances laptop i e American Japanese etc A USB charging station for electronic devices is available at the registration desk EMBL Merchandise If you are interested in purchasing an EMBL souvenir products presented in the glass display in the registration area please ask at the registration desk for more information Health and safety notes Please read EMBL s COVID 19 safety policy for on site events Do not smoke in any EMBL building Eating and drinking is prohibited in all laboratories Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required The first aid room is located next to the ATC Registration Desk room 10 205 Dial the Emergency number 222 from any EMBL internal phone only Where is the accident What happened How many injured Emergency number 06221 387 7821 from mobile phones Please report all accidents to the conference officer at the registration desk In case of fire Press the nearest fire alarm button or the Emergency number 222 from any internal phone A loud fire alarm will go off if an evacuation is required On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting points Do not use the lifts Beyond first aid Please remember to bring your own medication if needed to the conference Note that the next pharmacy is a 4 minute drive from the EMBL but for many medications you will be required to see a doctor to get a prescription Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg In any case the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary Internet Wi Fi is available on campus Log in using the EMBL Events network and the event specific password which will be provided on site The eduroam network secure worldwide roaming access service developed for the international research and education community is also available Lost and found Lost and Found items are kept at the registration desk until the end of the conference Luggage There are lockers available on site to store your luggage which require a 2 EURO coin to operate There is another luggage room on level E0 which is free to use but remains unlocked during the conference Nursing room There is a nursing room available in the ATC Rooftop Lounge on level A29 Photography During the conference an EMBL Photographer may be taking photos If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Printing We can help to print your boarding pass train ticket Please send it to events embl de and collect your print outs at the registration desk Room for prayer yoga and meditation There is a room for prayer meditation and yoga located on level E0 behind the Auditorium Please be respectful of others using the room Sightseeing A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing Travel to and from the venue During the event we provide conference shuttle buses to and from EMBL In addition there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time Information on the shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page Map to walk from ISG Hotel to EMBL Additional information Address EMBL Heidelberg Meyerhofstra e 1 69117 Heidelberg Germany ATC orientation map Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page Technical requirements and event software Technical requirements Below you will find the software and technical requirements for this course Participants need to bring their own laptops which will be used to remotely access EMBL virtual machines with pre installed software You will need admin rights to install the software required to access the virtual machines If you do not have admin rights please contact your technical support team in advance to make sure the software can be installed If you have a non standard HDMI port other than type A you need to bring an adaptor Keyboard and PC mouse are available for use with a standard USB port If you have a different port type such as USB C you will need to bring your own Event software The EMBL eCampus learning platform will be used to collaborate communicate and network with all of the course participants All participants will receive information on how to join shortly before the course We recommend using Chrome Safari or Mozilla Firefox browsers for eCampus Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page COVID 19 related questions COVID 19 information for on site events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other events or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 x 9...

John Baeten, Vladimir Benes, Björn Textor, Pingfang Liu, Laura Villacorta

EMBL Course

EMBL Heidelberg

6 November - 10 November 2023

Edit

October 18, 2023 00:002023ConferenceEMBL Heidelberg, Virtual

Description OverviewSpeakersProgrammePractical informatonSponsorsAboutMedia kitPre conference workshops Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Symposium overview The ability to grow human tissues from stem cells in 3D culture has the potential to revolutionise the drug discovery process and regenerative medicine Building on a long tradition of cell and developmental biology knowledge organoids resembling a variety of human tissues have been generated This conference will bring together the leading researchers in this field to establish a new research community and reveal parallels between various tissue models The aim of this meeting is to bring together researchers from different fields to enhance our understanding of how organoids can be formed and maintained how they can be used to study disease and how we might eventually use them to regenerate and replace human organ tissue Session topics Concepts from development and evolution Building organoid complexity Organoids from adult stem cells Organoids in regenerative medicine therapy Organoids in disease modeling What past participants say about the symposium Organoid biology is all about interaction across multiple disciplines and methods TheEMBO EMBL Symposium has been a wonderful venue for hosting such cross talks Francesco Cambuli Columbia University USA This conference was a great oppotunity to bring together experts on the organoid field creating an important network for future collaborations Veronica Foletto University of Trento Italy This symposium was one of the best conferences I attended so far Beside the location and networking possibilities I would like to emphasize the great choice of speakers and posters The presented data and new applications were astonishing and represented the development of organoid field very nicely Thank you very much for the organization of such a great symposium Thomas D ullary Julius Maximilians Universit t of W rzburg Germany Please see EMBL s COVID 19 safety recommendations if attending the on site event Speakers Keynote speaker Melissa Little Murdoch Children s Research Institute Australia Magdalena Zernicka Goetz University of Cambridge and California Institute of Technology UK and USA Speakers Cantas Alev Remote speaker Kyoto University Japan Gray Camp University of Basel Switzerland Silvia Cappello Max Planck Institute of Psychiatry Germany Hans Clevers F Hoffmann La Roche Ltd Switzerland Switzerland Penney Gilbert University of Toronto Canada Anne Grapin Botton Max Planck Institute of Molecular Cell Biology and Genetics Germany Muzlifah Haniffa Newcastle University and Wellcome Sanger Institute UK Kim Bak Jensen University of Copenhagen Denmark J rgen Knoblich Institute of Molecular Biotechnology IMBA Austria Joo Hyeon Lee University of Cambridge UK Sasha Mendjan Institute of Molecular Biotechnology Austria Christine Mummery Leiden University The Netherlands Josef Penninger Helmholtz Centre for Infection Research Germany Anne Rios Princess M xima Center The Netherlands Jason Spence University of Michigan USA Takanori Takebe Cincinnati Children s Hospital Medical Center USA Sara Wickstr m Max Planck Institute for Molecular Biomedicine Germany Scientific organisers Meritxell Huch Max Planck Institute of Molecular Cell Biology and Genetics Germany Karl R Koehler Boston Children s Hospital and Harvard Medical School USA Madeline Lancaster MRC Laboratory of Molecular Biology UK Esther Schnapp EMBO Press Germany Conference organiser Lea Hohmann EMBL Heidelberg Germany Programme Got something to say Tweet it EESOrgan Please note that due to the ongoing pandemic situation some speakers may need to join virtually to give their talk and the programme is subject to change For registered participants recorded talks will be accessible on demand for 2 weeks after the end of the event unless indicated otherwise Day 1 Wednesday 18 October 2023 Time Europe Berlin Speaker14 00 16 00Registration and light refreshments14 30 15 30Pre conference workshops withAmsbio Carl ZEISS Evident STEMCELL TakaraBioMore information will be shared closer to the conference16 00 16 15Opening remarks by Esther Schnapp16 15 18 50Session 1 Concepts from development and evolutionSession Chair Madeleine Lancester MRC Laboratory of Molecular Biology Cambridge UK16 15 16 40Charting human development with organoid single cell technologiesGray Camp University of Basel SwitzerlandNot available on demand16 40 16 55The emergence of actin stars for epithelium coordination and tissue patterningAmlan Barai Institut de Biologie du D veloppement de Marseille IBDM CNRS Aix Marseille University FranceNot available on demand16 55 17 10Morphogen stepwise temporal gradient driven neural induction shapes brain organoid development into a single expanded neuroepithelium with enhanced cortical identityAnna Pagliaro Prinses Maxima Centrum The NetherlandsNot available on demand17 10 17 40Coffee Break and Meet the speakers17 40 18 05Human iPSC Intestine Mimetics co differentiated with Mesenchymal Endothelial and Enteric Nervous TissueJason Spence University of Michigan USANot available on demand18 05 18 20Modulation of human placental development by uterine Natural Killer cells new insights using trophoblast organoidsElisa Magistrati Friedrich Miescher Institute for Biomedical Research SwitzerlandNot available on demand18 20 18 35Multimodal signal integration for tissue scale decision makingCornelia Schwayer Friedrich Miescher Institute for Biomedical Research SwitzerlandNot available on demand18 35 18 50Cell type tracking in intestinal organoids reveals commit then sort differentiation modelSander Tans AMOLF institute The Netherlands18 50 19 35Keynote Lecture Extending what we know about kidney organoids to deliver on disease modelling and tissue engineeringMelissa Little Murdoch Children s Research Institute Australia19 35 21 05Dinner in Canteen21 05 23 00After dinner drinks Day 2 Thursday 19 October 2023 Time Europe Berlin Speaker09 00 12 05Session 1 Concepts from development and evolution cont Session Chair Meritxell Huch Max Planck Institute of Molecular Cell Biology and Genetics Germany09 00 09 25Decoding the developing human immune systemMuzlifah Haniffa Newcastle University and Wellcome Sanger Institute UK09 25 09 40Human Pluripotent Stem Cells Derived Inner Ear Organoids Recapitulate Otic Development In Vitro Marta Roccio University Hospital Zurich SwitzerlandNot available on demand09 40 09 55Fueling Cellular Transformation Insulin s Dynamic Role in Generating Airway and Alveolar Lung Organoids from Endodermal NKX2 1 Cells Mirian Romitti Universit libre de Bruxelles ULB Belgium09 55 10 25Coffee Break and Meet the speakers10 25 10 50Organoids to probe infectionsJosef Penninger Helmholtz Centre for Infection Research Germany10 50 11 05Recapitulation of human early embryonic development in artificial micro environments from notochord to gastrula Zhe Wang Kyoto University Japan11 05 11 20Spatial and temporal regulation of cell cell fusion in human placentaVeronica Farmer Duke University USA11 20 12 05Keynote Lecture To be presented on siteMagdalena Zernicka Goetz California Institute of Technology USANot available on demand12 05 13 30Lunch13 30 16 25Session 2 Building organoid complexitySession Chair Kim Bak Jensen University of Copenhagen Denmark13 30 13 55Self organization in pancreas organoids formation of complex ductal networksAnne Grapin Botton Max Planck Institute of Molecular Cell Biology and Genetics GermanyNot available on demand13 55 14 10Complex intestinal organoid models to study immune epithelial interactions Joana F Neves King s College London United Kingdom14 10 14 35Overcoming challenges of brain organoids to uncover what it means to be pluripotent Madeline Lancaster MRC Cambridge UK14 35 15 05Coffee Break and Meet the speakers15 05 15 30Reconstituting human axial development with axioloidsCantas Alev Kyoto University JapanNot available on demand remote talk15 30 15 45Differentiating stem cells one at a time in 3D reveals how the dynamical build up of local microniches controls tissue organisation in gastruloids and bile duct organoids Virgile Viasnoff National University of Singapore Singapore15 45 16 00Design and control of in vitro microenvironments with simple CUBE device to achieve organoid architecture Masaya Hagiwara RIKEN Japan16 00 16 25Multi chamber cardioids unravel human heart development and cardiac defectsSasha Mendjan Institute of Molecular Biotechnology Austria16 25 16 45Flash talks 52 Reconstructing the development of fetal insulinproducing enteroendocrine cellsAkkerman Ninouk 74 Light dependent modulation of microRNA expression in human retinal organoidsCeliker Canan 91 Developing an immunocompetent in vitro 3D brain model of alzheimer s disease to study the neuroprotective effects of estrogenDemetriou Aphrodite 112 Supracellular contractility of fibroblasts in homeostasis injury and wound healingGlisovic Neda 181 Ex utero cell derived model of the human post implantation embryo developmentBondarenko Vladyslav 183 Microfluidics driven tissue patterning of neural organoidsPark JiSoo 219 Local tissue mechanics controls homeostatic livecell extrusion in the small intestineSpoelstra Willem Kasper 243 Communication of cellular fitness in intestinal organoidsvan Luyk Merel 245 Bacterial infection of intestinal organoidsvon Peinen Kristin16 45 18 45Poster Session 1 odd with beer and snacksView poster listing here18 45Free evening Day 3 Friday 20 October 2023 Time Europe Berlin Speaker09 00 12 00Session 3 Organoids from adult stem cellsSession Chair Penney Gilbert University of Toronto Canada09 00 09 25Organoids to model human diseaseHans Clevers F Hoffmann La Roche Ltd SwitzerlandNot available on demand09 25 09 40PIEZO dependent mechano sensing of the niche is essential for intestinal stem cell fate decision and maintenance Meryem B Baghdadi Institut Curie France09 40 09 55Multilineage liver organoids recapitulate aspects of the liver peri portal region and faithfully model cholestatic liver diseaseAleksandra Sljukic Max Planck Institute of Molecular Cell Biology and Genetics MPI CBG GermanyNot available on demand09 55 10 25Coffee Break and Meet the speakers10 25 10 40Intestinal organoid and organ on chip models to recapitulate celiac disease pathophysiology Sebo Withoff University Medical Center Groningen The NetherlandsRemote speaker10 40 10 55Host response to Pseudomonas aeruginosa and Staphylococcus aureus in an ex vivo human airway model of cystic fibrosisPawan Parajuli Commonwealth Scientific and Industrial Research Organisation CSIRO Australia10 55 11 20Regulation of stem cell dynamics through niche derived signals and forcesSara Wickstr m Max Planck Institute for Molecular Biomedicine GermanyNot available on demand11 20 11 45Esther Schnapp Editor Talk Transparent Publishing at EMBO Press11 45 13 30Lunch13 30 16 25Session 4 Organoids in regenerative medicine therapySession Chair Anne Grapin Botton Max Planck Institute of Molecular Cell Biology and Genetics Germany13 30 13 55Understanding interconnectedness in liver development and diseaseTakanori Takebe Cincinnati Children s Hospital Medical Center USA Not available on demand13 55 14 10Golgi organization is a determinant of stem cell function in the small intestine Sandra Scharaw Karolinska Institutet SwedenNot available on demand14 10 14 35Skin organoids for developmental modeling and therapyKarl Koehler Boston Children s Hospital and Harvard Medical School USANot available on demand14 35 15 05Coffee Break and Meet the editors and Meet the speakers15 05 15 30In silico predictions coupled with the mini IDLE predictive assay identifies myofiber derived biomolecules dictating muscle stem cell return to quiescencePenney Gilbert University of Toronto Canada15 30 15 45Generation of complex human induced pluripotent stem cell derived bone marrow organoids to model hematopoietic development and disease Stephanie Frenz Wiessner Dr von Hauner Children s Hospital Ludwig Maximilians University Munich GermanyNot available on demand15 45 16 00Cerebral organoids display dynamic clonal growth with lineage replenishment Christopher Esk University of Innsbruck Austria16 00 16 25Cardiovascular diseases and drugs where are we with hiPSC models Christine Mummery Leiden University Medical Centre The NetherlandsNot available on demand16 25 16 45Flash talks 106 iPSC derived human organoid based model of intestinal filovirus infectionFlores Elizabeth Yvonne 164 Volumetric compression by heterogeneous scaffold embedding promotes cerebral organoid growth and maturationMa Shaohua 172 Generation and characterization of microgliacontaining human forebrain assembloidsMichels Susanne 220 Covalent tracking of DNMT1 specific activity in lung cancer spheroids Stankevicius Vaidotas 236 Collective organization of circadian rhythms in murine intestinal organoidsTonin Elena 238 Screening gastric cancer patient derived organoids develops the first in class anti invadopodia therapeutic antibodyTsai Kelvin Kunchih 242 Exploring human inner ear organoids Singlecell analysis of oto pharyngeal development and comparative profiling to human inner ear tissue across developmental stagesvan der Valk Wouter 254 Differentiated tubuloids to model human distal nephron Patho PhysiologyPou Casellas Carla16 45 18 45Poster Session 2 even with beer and snacksView poster listing here18 45 21 00Conference dinner in the canteen 21 00 00 00Party with Who2Ladies Day 4 Saturday 21 October 2023 Time Europe Berlin Speaker09 00 12 25Session 5 Organoids in disease modelingSession Chair Karl Koehler Boston Children s Hospital and Harvard Medical School09 00 09 25Guiding Intestinal Stem Cell Fate Kim Bak Jensen University of Copenhagen DenmarkNot available on demand09 25 09 40Salmonella Typhimurium and Shigella flexneri use alternative virulence strategies to colonize the human enteroid and colonoid epithelium Petra Geiser Uppsala University Sweden09 40 09 55Extracellular signaling in neurodevelopmental disordersSilvia Cappello Ludwig Maximilian University of Munich GermanyNot available on demand09 55 10 25Coffee Break and Meet the speakers10 25 10 50Organoid cellular cancer immunity models in motion Anne Rios The Princess Maxima Center of Pediatric Oncology10 50 11 05RFX6 Regulates Human Intestinal Patterning and Function J Guillermo Sanchez Cincinnati Children s Hospital United States of America11 05 11 30Liver organoids to study regeneration and cancer across biological scalesMeritxell Huch Max Planck Institute of Molecular Cell Biology and Genetics GermanyNot available on demand11 30 11 45Isogenic patient derived organoids reveal early neurodevelopmental defects in spinal muscular atrophy initiationNatalia Rodriguez Muela German Center for Neurodegenerative Diseases DZNE Germany11 45 12 10Genetic screening and neural network pathology in cerebral organoids J rgen Knoblich Institute of Molecular Biotechnology IMBA AustriaNot available on demand12 10 12 25Closing Remarks and Poster Prize Announcement12 25 12 45Packed Lunch and departure12 45Airport shuttle to terminal 1 30 EUR tickets may be purchased on site Practical informaton Registration fees and abstract submission On site registration fees include admission conference materials meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Virtual registration fees include access to all of the talks livestreamed and on demand and facility to submit questions On site Academia 700On site PhD Student 600On site Industry 900Virtual Academia 200Virtual PhD Student 150Virtual Industry 250 A letter to support your visa application will be issued on request once payment of the registration fee is confirmed We recommend that you book your visa appointment as soon as possible to avoid any delay with your visa application Accredited journalists may be eligible to register for complimentary press registration Registrants may be required to provide accreditation or equivalent proof of press membership after registration Please contact Lea Hohmann for more information Please note that we do not offer complimentary registrations for editors of scientific journals Confirmation and payment Registration will be on a first come first served basis Your place can only be confirmed after payment of the registration fee If you are added to our waiting list please consider taking advantage of our offerings to participate virtually On site participants Types of payments accepted are international bank transfers and credit card payments Virtual participants We are only able to accept card payments In exceptional cases we can accept bank transfers Please contact events embl de for details Abstract submission Only participants registering to attend the on site event are eligible to submit an abstract Abstracts will not be accepted from virtual participants After registration you can submit your abstract via a separate link that will be provided in the email confirmation Alternatively you can access the link on the confirmation page directly after registering The same login credentials are used for both processes Please note Abstract body The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised Title The title should not exceed 20 words Only the first word of the title should start with a capital letter and the rest should be lowercase Authors and affiliations Please fill in the author s details as requested in the online form The compulsory fields are First Name Last Name Organisation Name Affiliation or Company Country and Email Kindly mark only one author in the role of First Author and please don t forget to indicate who will be the Presenter Please enter your co authors correctly via the system by adding accounts together with their organisation institute Do not copy paste them into the body of the abstract text as they will not be indexed in the abstract book Presentation types When submitting your abstract you can apply for an oral or poster presentation A selection process will take place with the results announced 2 3 weeks after the abstract submission deadline For detailed instructions on how to submit a conference abstract follow the instructions provided in this video Please check our FAQs pages for further information on how to submit an abstract Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of both registration fee waivers and travel grants These are available for on site participants at EMBL Conferences and EMBO EMBL Symposia and for on site and virtual participants at EMBO Workshops We are currently working on securing funding for all virtual participants and ask that you please apply for financial assistance for both on site and virtual participation Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course or conference Travel grant The travel grant will cover the cost of travel to an on site event airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from within Europe up to 1000 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from outside Europe up to 500 for any participant travelling to an EMBO Workshop up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Workshop up to 700 for any participant working in Croatia Czech Republic Estonia Greece Hungary Italy Lithuania Luxembourg Poland Slovenia and Turkey travelling to an EMBO Workshop Registration fees are only covered for EMBO Workshops The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Application On site participants You may apply for financial assistance when submitting your abstract In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Virtual participants If you are attending virtually you can apply for financial assistance in the submission portal by the abstract deadline Read the instructions on how to apply for financial assistance Only submissions for financial assistance will be accepted Presentation abstracts cannot be submitted here and will be declined In your application you will be asked to summarise your current work answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Selection The scientific organisers will select the recipients of all financial assistance during the abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details View our list of external funding opportunities and information on attending a conference as an event reporter For further information about financial assistance please refer to the FAQ page Accommodation and shuttles Accommodation is not included in the conference registration fee As further changes in our events are possible you should book flights trains and hotels with flexible options and favourable cancellation conditions The hotels below have rooms on hold for participants until 20 September 2023 in some cases at special rates Please email the hotel directly quoting the booking code EES23 11 to confirm the exact price of the room Hotel AnlageHotel ibis HeidelbergPremier Inn Heidelberg CityHotel Bayrischer Hof ISG Hotel Staycity Aparthotel HeidelbergB B HotelLeonardo Hotel Heidelberg City CentreSteffi s Hostel HeidelbergExzellenz HotelMeininger HeidelbergHotel Vier Jahreszeiten HeidelbergHotel Monpti Conference shuttle buses Conference shuttle buses are free of charge for participants and depart from designated bus stops near the hotels to EMBL and back mornings and evenings The bus stops for this conference are Hotel Staycity Speyerer Str 7 Kurf rsten Anlage Opposite Main Train Station Hotel Premier Kurf rsten Anlage 23 Leonardo Hotel Heidelberg City Center Bergheimer Str 63 Neckarmuenzplatz Heidelberg Tourist Information Peterskirche Bus stop ISG Hotel Im Eichwald 19 CLICK HERE FOR THE BUS SCHEDULE as of 10 October 2023 View Conference shuttle bus stops and hotels in a larger map Please note that not every bus stop will be used for every event Further details Address EMBL Meyerhofstra e 1 69117 Heidelberg Germany For further information on getting to EMBL Heidelberg visit Public Transportation to the Venue For information about accommodation and local transportation please refer to the FAQ page On site information Catering All meals and coffee breaks are included in the registration fee Our catering staff will prepare a wide variety of vegetarian meals meat and fish dishes soups pasta fresh fruit and vegetables as well as a variety of desserts Please wear your badge at all times when serving yourself No food or drinks are allowed in the auditorium Charging lockers There are lockers available next to the stairs leading down into the Auditorium You will find some of those equipped with sockets to charge your smartphone tablet etc Electricity and charging station In most places the electricity is 220 volts AC 50 cycles An adaptor and a plug that fits the German socket may be needed for your appliances laptop i e American Japanese etc A USB charging station for electronic devices is available at the registration desk EMBL merchandise If you are interested in purchasing an EMBL souvenir products presented in the glass display in the registration area please ask at the registration desk for more information Health and safety notes Please read EMBL s COVID 19 safety policy for on site events Do not smoke in any EMBL building Eating and drinking is prohibited in the Auditorium and all laboratories Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required The first aid room is located next to the ATC Registration Desk room 10 205 Dial the Emergency number 222 from any EMBL internal phone only Where is the accident What happened How many injured Emergency number 06221 387 7821 from mobile phones Please report all accidents to the conference officer at the registration desk In case of fire Press the nearest fire alarm button or the Emergency number 222 from any internal phone A loud fire alarm will go off if an evacuation is required On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting points Do not use the lifts Beyond first aid Please remember to bring your own medication if needed to the conference Note that the next pharmacy is a 4 minute drive from the EMBL but for many medications you will be required to see a doctor to get a prescription Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg In any case the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary Internet Wi Fi is available on campus using the EMBL Events network and the event specific password which will be provided on site The eduroam network secure worldwide roaming access service developed for the international research and education community is also available Lost and found Lost and Found items are kept at the registration desk until the end of the conference Luggage There are lockers available on site to store your luggage which require a 2 EURO coin to operate There is another luggage room on level E0 which is free to use but remains unlocked during the conference Nursing room There is a nursing room available in the ATC Rooftop Lounge on level A29 Photography During the conference an EMBL Photographer may be taking photos If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Printing We can help to print your boarding pass train ticket Please send it to events embl de and collect your print outs at the registration desk Room for prayer yoga and meditation There is a room for prayer meditation and yoga located on level E0 behind the Auditorium Please be respectful of others using the room Sightseeing A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing Travel to and from the venue During the event we provide conference shuttle buses to and from EMBL In addition there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time Information on the conference shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page Useful German expressions HelloHalloGoodbyeAuf Wiedersehen formal Tsch ss informal Good morningGuten MorgenGood afternoonGuten TagGood eveningGuten AbendGood nightGute NachtI m sorryEs tut mir leidExcuse me Entschuldigen SieHow are you Wie gehts I m fine thanks And you Mir geht es gut danke Und Dir Ihnen What is your nameWie hei en Sie formal Wie hei t du informal My name is Ich hei e Do you speak EnglishSprechen Sie englisch I don t understandIch verstehe nichtPlease speak more slowlyK nnen Sie bitte langsamer sprechenThank youDankesch nWhere is the toilet Wo ist die Toilette Please call me a taxiBitte rufen Sie mir ein TaxiHow do I get to Wie komme ich zum zur A beer two beers pleaseEin Bier zwei Bier bitteA glass of red white wine pleaseEin Glas Rot Weisswein bitteThe menu pleaseDie Speisekarte bitteIs there a local speciality Gibt es eine Spezialit t aus dieser Gegend I m vegetarianIch bin VegetarierIt was deliciousEs war hervorragendThe bill pleaseDie Rechnung bitteI have a headacheIch habe KopfschmerzenI have a sore throatIch habe HalsschmerzenMy stomach hurtsIch habe MagenschmerzenI m allergic toIch bin allergisch gegenI need a doctor who speaks EnglishIch brauche einen Arzt der englisch spricht Virtual participation What s included Access to all the livestreamed talks Video library of the recorded talks during and after the event Facility to submit questions Please note that only on site participants are able to submit abstracts and participate in the poster sessions Event platform We are using an event platform for this conference More information about the platform will be shared ahead of the conference Guidelines Do not broadcast the conference to unregistered participants You are encouraged to tweet and post about the event Tweet unless the speaker specifically says otherwise but be mindful of unpublished data Please do not capture transmit or redistribute data presented at the meeting Additional information can be found in our Code of Conduct Health and well being It is important to stay healthy and move around especially when you are attending an event virtually We have put together a few coffee break stretches and yoga videos in the conference platform for you to enjoy during the event How to ask questions Please use the Q A function in the event platform If you have any other questions you can go to the Help Desk in the event platform Click on more on the top menu and click Help Desk Time zone The programme is planned based on the Europe Berlin time zone unless otherwise stated Please take your time zone into consideration when planning your attendance Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page COVID 19 related questions COVID 19 information for onsite events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Gold Sponsors Silver Sponsors Bronze sponsors Event sponsors Axion BioSystems Bio Techne BIOMEX Cell Research MaxWell Biosystems Molecular Devices Nikon Europe BV Optics11 Life The FEBS Journal World Precision Instruments Xceltis GmbH Event supporter Media partners Disease Models Mechanisms The Company of Biologists Journal Development The Company of Biologists journal EMBO Journal an EMBO Press journal FEBS Journal a FEBS Press journal FEBS Letters a FEBS Press journal International Union of Biochemistry and Molecular Biology Open Biology a Royal Society journal Bio Essays a Wiley Online Library Advanced Biology a Wiley Online Library Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de About EMBO EMBL Symposia promote scientific communication and collaboration in the European research area They provide scientists with a platform to discuss and exchange ideas on forward looking topics and new developments in the life sciences Topics emphasise upcoming developments and the interdisciplinary nature of related fields Jointly funded and organised by EMBO and EMBL and complementary to their respective courses workshops and conference programmes the symposia promote scientific communication and collaboration All symposia are held in the EMBL Advanced Training Centre ATC in Heidelberg Germany or virtually Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9 Leaderboard 728 90 Pre conference workshops For on site participants only The following industry workshops will be hosted by the sponsors of EMBO EMBL Symposium Organoids modelling organ development and disease in 3D culture prior to the start of the event Three Dimensional Reconstitution of Liver Epithelial Tissue Structures ex vivo Enhanced with Animal Origin Free Recombinant Proteins and Culture Media by Prof Tanimizu The University of Tokyo Helix B01 Imaging and Analysis of 3D cell cultures using ZEISS microscope systems and Arivis by Dr Volker D ring and Dr Philipp Seidel Carl Zeiss Microscopy GmbH Main Auditorium Deep live cell imaging with new IXplore SpinSR NIR add on by Stefan Marawske Kristina Mayer EVIDENT Europe FlexLab A Innovations in In Vitro Tissue Modeling Hepatic and Airway Organoids by Riya Sharma and Salvatore Simmini STEMCELL Technologies FlexLab B Newer technologies assisting the sustainable disease modelling by Karthi Rajamani Takara Bio Helix A01 on Wednesday 18 October 2023 14 30 15 30 In order to read the abstract of each workshop please click on the corresponding links above Participation in this workshop is free of charge for registered on site conference attendees The available place is limited first come first served All registered conference attendees will receive an email with a registration link shortly All pre conference workshops will take place simultaneously therefore please choose the one you would be interested in the most...

Meritxell Huch, Karl R. Koehler, Madeline Lancaster, Esther Schnapp

EMBO | EMBL Symposium

EMBL Heidelberg, Virtual

17 October - 19 October 2023

Open Virtual Ensembl REST API Workshop

Edit

October 17, 2023 00:002023CourseVirtual

Description Work with Ensembl to master the Ensembl REST API and flexibly access genome wide data such as genes variants regulatory features homologues and alignments...

Louisse Paola Mirabueno

Virtual

11 October 2023

Accessing and interpreting predicted protein structures from AlphaFold database

Edit

October 11, 2023 15:302023WebinarVirtual

Description AlphaFold database AlphaFold DB provides open access to over 200 million protein structure predictions to accelerate scientific research This webinar aims to provide a comprehensive introduction to AlphaFold DB Participants will gain a clear understanding of the fundamental concepts principles and functionalities of the database They will learn how to access and evaluate predicted protein structures explore the underlying technologies and algorithms used in AlphaFold and identify the potential applications of AlphaFold DB in their research...

Virtual

11 October - 14 October 2023

The non-coding genome

Edit

October 11, 2023 00:002023ConferenceEMBL Heidelberg, Virtual

Description OverviewSpeakersProgrammePractical informationSponsorsAboutMedia kit Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Symposium overview Over the past two decades advances in transcriptomic methods have led to the discovery of a very rich and diverse set of RNA transcripts short and long that serve as regulators rather than templates for protein production Many of these transcribed elements are encoded in noncoding regions of the genome with other regulatory and structural DNA elements of known and unknown functions While the catalogs of such elements are very rich and an ever increasing number are implicated in almost every known biological process there are still many key open questions Often these important problems are tackled and discussed within different sub communities including the mature fields of microRNAs miRNAs and piRNAs and the emerging fields focused on longer linear noncoding RNAs lncRNAs circular RNAs circRNAs and other non transcribed yet functional genomic elements This symposium traditionally brings together members of these communities enabling researchers focusing on different classes of non coding elements to interact and learn from each other We are pleased to return to doing this at an in person meeting this year following the virtual edition held in 2021 For 2023 the main pillars of the meeting will remain with sessions on miRNAs piRNAs lncRNAs and circRNAs alongside sessions showcasing less RNA centric fields such as heterochromatin and telomere biology and transcribed regulatory regions Topics that have received relatively limited attention in previous meetings will also feature such as ncRNAs in plants and RNA therapeutics which has become a particularly active field due to the current pandemic Session topics Small RNAs Non coding genome and disease Unconventional RNA structure and mechanisms Transcriptional regulation by non coding RNA and DNA Genome organisation and epigenetic regulation and development Long non coding RNAs What past participants say about the symposium The Non coding Genome was a truly inspiring meeting both in terms of topics and the excellent level of the talks with a good balance of novel and published work Thanks to the organisers for providing me the opportunity to present my latest work at this high profile event which also enabled networking with peers publishers and industries Roberto Simone UCL UK Please see EMBL s COVID 19 safety recommendations if attending the on site event Speakers Keynote speakers Julius Brennecke Institute of Molecular Biotechnology Austria Ling Ling Chen Shanghai Institute of Biochemistry and Cell Biology China Speakers Peter Andersen Aarhus University Denmark David Bartel Massachusetts Institute of Technology USA Fr d ric Berger Gregor Mendel Institute of Molecular Plant Biology Austria Nadya Dimitrova Yale University USA Ines Drinnenberg Institut Curie France Archa Fox The University of Western Australia Australia Maite Huarte Universidad de Navarra Spain Nicola Iovino Max Planck Institute of Immunobiology and Epigenetics Germany Joanna Jachowicz Institute of Molecular Biotechnology Austria Jeannie Lee Harvard Medical School USA Katherine McJunkin National Institute of Diabetes and Digestive and Kidney Diseases USA Eric Miska University of Cambridge UK Shinichi Nakagawa Hokkaido University Japan Michael Nodine Wageningen University Research The Netherlands Claire Rougeulle Epigenetics and Cell Fate Centre France Edda Schulz Max Planck Institute for Molecular Genetics Germany Cynthia Sharma Julius Maximilians Universit t W rzburg Germany Yukihide Tomari The University of Tokyo Japan J rg Vogel Helmholtz Centre for Infection Research Germany Scientific organisers Marc B hler Friedrich Miescher Institute for Biomedical Research Switzerland Ana Eul lio Imperial College London UK Joshua Mendell UT Southwestern Medical Center USA Gisela Storz National Institutes of Health USA Igor Ulitsky Weizmann Institute of Science Israel Conference organiser Inna B sselmann EMBL Heidelberg Germany Programme Got something to say Tweet it EESNoncoding Please note that the programme is subject to change For registered participants recorded talks will be accessible on demand for 2 weeks after the end of the event All times in the programme below are shown as the time in Europe Berlin Programme is preliminary and subject to change Day 1 Wednesday 11 October Time Europe Berlin Title 11 30 13 00 Registration and light refreshments13 00 13 15Opening remarksSession 1 Small RNAsChairs Joshua Mendell and Ana Eulalio13 15 13 40 Argonaute catalyzed slicing and conformational dynamicsDavid Bartel Massachusetts Institute of Technology USA13 40 14 05Changeability of piRNA production patterns negatively correlates with the efficiency of their biogenesisYukihide Tomari The University of Tokyo Japan14 05 14 30 Theme and variations Emerging diversity in mechanisms of miRNA decayKatherine McJunkin National Institute of Diabetes and Digestive and Kidney Diseases USA14 30 14 55Small RNA functions in plant embryosMichael Nodine Wageningen University Research The NetherlandsNot available on demand14 55 15 25Coffee break15 25 15 50Regulation of protein activity by base pairing small RNAsGisela Storz National Institutes of Health USA15 50 16 05Natural and genetically engineered mammalian canonical RNAi in vivoPetr Svoboda Czech Academy of Sciences Czech Republic16 05 16 20agoTRIBE detects microRNA target interactions transcriptome wide in single cells Marc Friedl nder Stockholm University Sweden16 20 16 35Casein kinase 1 and 2 phosphorylate a conserved cluster of argonaute to control microRNA function Vivek Nilesh Shuah Chu de Qu bec Universit Laval Cancer Research Center Canada16 35 16 50Quantitative measurement of RNA protein interactions in vivo Dmitry Kretov Boston University School of Medicine USA16 50 17 20Coffee break17 20 18 05 Keynote talk 1 Biogenesis function and potential application of circular RNAsLing Ling Chen Shanghai Institute of Biochemistry and Cell Biology China18 05 19 30Dinner in canteen19 30 21 00 Drinks in ATC rooftop lounge Day 2 Thursday 12 October Time Europe Berlin Title Session 2 Non coding genome and diseaseChairs Edda Schulz and Nadya Dimitrova09 00 09 25Deregulation of long noncoding RNAs in cancerNadya Dimitrova Yale University USA09 25 09 50CRISPR Cas9 based endogenous RNA targeting in bacteria from discovery to applicationsSahil Sharma University of W rzburg Germany09 50 10 15Leveraging bacterial RNA biology knowledge for the development of programmable RNA antibioticsJ rg Vogel Helmholtz Centre for Infection Research Germany10 15 10 40Unravelling the role of microRNAs in bacterial pathogen host interactionAna Eul lio Imperial College London UKNot available on demand10 40 11 10Coffee break11 10 11 25SINEUP RNA rescues molecular phenotypes associated with CHD8 suppression in Autism Spectrum Disorder model systems Marta Biagioli University of Trento Italy11 25 11 40Haploinsufficiency of human DGCR8 results in primate specific RNAs dysregulation and pluripotency defects Ana Colomer Boronat University of Granada Spain11 40 11 55Positive feedback amplification of antiviral signaling by endogenous double stranded RNAs in autoimmune diseases Doyeong Ku Korea Advanced Institute of Science and Technology Republic of Korea11 55 12 10The Alzheimer s disease risk factor RBFOX1 is a major regulatory hub for Alzheimer associated circRNAs Sambhavi Puri Boston University School of Medicine USA 12 10 13 30Meet the speakers and lunchSession 3 Unconventional RNA structure and mechanismsChairs Gisela Storz and Julius Brennecke13 30 13 55Confined environments induce polarized paraspeckle condensatesArcha Fox The University of Western Australia AustraliaNot available on demand13 55 14 20piRNA dynamics in mammalian genomesEric Miska University of Cambridge UK14 20 14 45Diversity of spatial genome organization Insights from LepidopteraInes Drinnenberg Institut Curie France14 45 15 00Molecular and physiological functions of circRNAs in the brain Sebastian Kadener Brandeis University USA15 00 15 30Coffee break meet the editors15 30 15 45A direct protein protein interaction network of cytoplasmic Drosophila piRNA pathway factors Mandy Jeske Heidelberg University Germany15 45 16 00Unistrand piRNA clusters have repeatedly emerged across the Drosophila genus to control endogenous retroviruses of the Gypsy family Susanne Bornel v University of Cambridge UK16 00 16 15Epstein Barr virus non coding RNA steers ribosomes into virus favorable translation Nara Lee University of Pittsburgh USA 16 15 16 45Flash talks 116 45 18 45Poster session 1 odd numbers 18 50Free evening Day 3 Friday 13 October Time Europe Berlin TitleSession 4 Transcriptional regulation by non coding RNA and DNAChairs Lingling Chen and Maite Huarte09 00 09 25The ChAHP complexesMarc B hler Friedrich Miescher Institute for Biomedical Research Switzerland09 25 09 50Contribution of lncRNAs to the control of X chromosome activity in early human developmentClaire Rougeulle Epigenetics and Cell Fate Centre France09 50 10 15Information processing at the Xist locusEdda Schulz Max Planck Institute for Molecular Genetics Germany10 15 10 40Recurrent innovation of germline genome regulation through paralog adaptationPeter Andersen Aarhus University Denmark10 40 11 10Coffee break11 10 11 35Epigenetic regulation by RNA G QuadruplexesJeannie Lee Harvard Medical School USANot available on demand11 35 11 50Mechanisms of long noncoding RNA dependent chromatin repression Aaron Johnson University of Colorado School of Medicine USA11 50 12 05Inseparable RNA binding and chromatin modification activities of a nucleosome interacting surface in PRC2 Chen Davidovich Monash University EMBL Australia Australia12 05 12 20LINE1 regulate human T cell function by assembling chromatin into condensates Beatrice Bodega University of Milan Italy12 20 13 30Meet the speakers and lunchSession 5 Genome organisation and epigenetic regulation and development Chairs Marc Buehler and Jeannie Lee13 30 13 55Inheritance of H3K9 methylation regulates genome architecture in early embryosNicola Iovino Max Planck Institute of Immunobiology and Epigenetics Germany13 55 14 20Meta analysis of RNA chromatin interaction datasetsIgor Ulitsky Weizmann Institute of Science Israel remote talk 14 20 14 45Short stories about long RNAs during early mammalian developmentJoanna Jachowicz Institute of Molecular Biotechnology Austria14 45 15 10Organization of the epigenetic information and its impact on transcriptionFr d ric Berger Gregor Mendel Institute of Molecular Plant Biology Austria15 10 15 40Coffee break15 40 15 55The lncRNA Sweetheart regulates compensatory cardiac hypertrophy after myocardial injury Sandra Rogala Georg Speyer Haus Germany15 55 16 10Network like condensation of satellite DNA into chromocenters safeguards nuclear mechanostability Franziska Br ndle ETH Zurich Switzerland16 10 16 25The effect of lncRNAs on gene regulation and inter chromosomal topology Philipp Maass SickKids Research Institute Canada remote talk 16 25 16 40Genome organization and lncRNAs synergistically control the dynamics of Hox gene expression during development Philippe Batut Princeton University USA16 40 17 10Flash talks 217 10 19 10Poster session 2 even numbers 19 10 21 00Conference dinner in the canteen21 00 24 00Party in the ATC foyer Day 4 Saturday 14 October Time Europe Berlin TitleSession 6 Long non coding RNAsChairs Archa Fox and Claire Rougeulle09 00 09 25Regulation of alternative splicing by short noncoding RNAShinichi Nakagawa Hokkaido University JapanNot available on demand09 25 09 50Noncoding RNA roles in the coordination of DNA replication and stress signalingMaite Huarte Universidad de Navarra Spain09 50 10 15New functions and regulators of noncoding RNAs in mammalsJoshua Mendell Howard Hughes Medical Institute UT Southwestern Medical Center USANot available on demand10 15 10 30A unified model for the surveillance of translation in diverse noncoding sequences Xuebing Wu Columbia University USA10 30 11 00Coffee break11 00 11 45piRNA guided transcriptional silencingKeynote talk 2 Julius Brennecke Institute of Molecular Biotechnology Austria11 45 12 00The Unexpected Match STAT3 NORAD Interaction a Novel Link in Antiviral Defense Amir Argoetti Yael Mandel Gutfreund Technion Israel Institute for Technology Israel remote talk 12 00 12 15The interplay between lncRNA CHERR and chromatin remodelling complex in cell division and lung cancer developmentGiulia Guiducci Barts Cancer Institute UK12 15 12 30Lncfoxp3 controls cell identity and function of human regulatory t cells Stefano Abbiati IFOM ETS The AIRC Institute of Molecular Oncology Italy12 30 12 45Closing remarks and poster prize12 45 13 30Packed lunch13 30DepartureOptional Bus to Frankfurt airport Terminal 1 Practical information Registration fees and abstract submission On site registration fees include admission conference materials COVID 19 safety measures meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Virtual registration fees include access to all of the talks livestreamed and on demand and facility to submit questions On site Academia 700On site PhD Student 600On site Industry 900Virtual Academia 200Virtual PhD Student 150Virtual Industry 250 NO visa support letters will be issued until payment of the registration fee is confirmed Accredited journalists may be eligible to register for complimentary press registration Registrants may be required to provide accreditation or equivalent proof of press membership after registration Please contact Inna Boesselmann for more information Please note that we do not offer complimentary registrations for editors of scientific journals Confirmation and payment Registration will be on a first come first served basis Your place can only be confirmed after payment of the registration fee If you are added to our waiting list please consider taking advantage of our offerings to participate virtually On site participants Types of payments accepted are international bank transfers and credit card payments Virtual participants We are only able to accept card payments In exceptional cases we can accept bank transfers Please contact events embl de for details Abstract submission Only participants registering to attend the on site event are eligible to submit an abstract Abstracts will not be accepted from virtual participants After registration you can submit your abstract via a separate link that will be provided in the email confirmation Alternatively you can access the link on the confirmation page directly after registering The same login credentials are used for both processes Please note Abstract body The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised Title The title should not exceed 20 words Only the first word of the title should start with a capital letter and the rest should be lowercase Authors and affiliations Please fill in the author s details as requested in the online form The compulsory fields are First Name Last Name Organisation Name Affiliation or Company Country and Email Kindly mark only one author in the role of First Author and please don t forget to indicate who will be the Presenter Please enter your co authors correctly via the system by adding accounts together with their organisation institute Do not copy paste them into the body of the abstract text as they will not be indexed in the abstract book Presentation types When submitting your abstract you can apply for an oral or poster presentation A selection process will take place with the results announced 2 3 weeks after the abstract submission deadline For detailed instructions on how to submit a conference abstract follow the instructions provided in this video Please check our FAQs pages for further information on how to submit an abstract Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of both registration fee waivers and travel grants These are available for on site participants at EMBL Conferences and EMBO EMBL Symposia and for on site and virtual participants at EMBO Workshops We are currently working on securing funding for all virtual participants and ask that you please apply for financial assistance for both on site and virtual participation Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course or conference Travel grant The travel grant will cover the cost of travel to an on site event airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from within Europe up to 1000 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from outside Europe up to 500 for any participant travelling to an EMBO Workshop up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Workshop up to 700 for any participant working in Croatia Czech Republic Estonia Greece Hungary Italy Lithuania Luxembourg Poland Slovenia and Turkey travelling to an EMBO Workshop Registration fees are only covered for EMBO Workshops The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Application On site participants You may apply for financial assistance when submitting your abstract In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Virtual participants If you are attending virtually you can apply for financial assistance in the submission portal by the abstract deadline Read the instructions on how to apply for financial assistance Only submissions for financial assistance will be accepted Presentation abstracts cannot be submitted here and will be declined In your application you will be asked to summarise your current work answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Selection The scientific organisers will select the recipients of all financial assistance during the abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details View our list of external funding opportunities and information on attending a conference as an event reporter For further information about financial assistance please refer to the FAQ page Accommodation and shuttles Accommodation Accommodation is not included in the conference registration fee As further changes in our events are possible due to COVID 19 you should book flights trains and hotels with flexible options and favourable cancellation conditions The hotels below have rooms on hold for participants until 13 September 2023 in some cases at special rates Please email the hotel directly quoting the booking code EES23 10 to confirm the exact price of the room Hotel AnlageHotel ibis HeidelbergPremier Inn Heidelberg CityHotel Bayrischer Hof ISG Hotel Staycity Aparthotel HeidelbergB B HotelLeonardo Hotel Heidelberg City CentreSteffi s Hostel HeidelbergExzellenz Hotel Meininger HeidelbergHotel Vier Jahreszeiten HeidelbergHotel Holl nder Hof Hotel Monpti Conference shuttle buses Conference shuttle buses are free of charge for participants and depart from designated bus stops near the hotels to EMBL and back mornings and evenings You can now find the Conference Bus Schedule here The bus stops for this conference are Hotel Staycity Speyerer Str 7 Kurf rsten Anlage Opposite Main Train Station Hotel Premier Kurf rsten Anlage 23 Leonardo Hotel Bergheimer Str Neckarmuenzplatz Peterskirche ISG Hotel View Conference shuttle bus stops and hotels in a larger map Please note that not every bus stop will be used for every event You can find the final bus schedule here Further details Address EMBL Meyerhofstra e 1 69117 Heidelberg Germany For further information on getting to EMBL Heidelberg visit Public Transportation to the Venue For information about accommodation and local transportation please refer to the FAQ page On site information Catering All meals and coffee breaks are included in the registration fee Our catering staff will prepare a wide variety of vegetarian meals meat and fish dishes soups pasta fresh fruit and vegetables as well as a variety of desserts Please wear your badge at all times when serving yourself No food or drinks are allowed in the auditorium Charging lockers There are lockers available next to the stairs leading down into the Auditorium You will find some of those equipped with sockets to charge your smartphone tablet etc Electricity and charging station In most places the electricity is 220 volts AC 50 cycles An adaptor and a plug that fits the German socket may be needed for your appliances laptop i e American Japanese etc A USB charging station for electronic devices is available at the registration desk EMBL merchandise If you are interested in purchasing an EMBL souvenir products presented in the glass display in the registration area please ask at the registration desk for more information Health and safety notes Please read EMBL s COVID 19 safety policy for on site events Do not smoke in any EMBL building Eating and drinking is prohibited in the Auditorium and all laboratories Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required The first aid room is located next to the ATC Registration Desk room 10 205 Dial the Emergency number 222 from any EMBL internal phone only Where is the accident What happened How many injured Emergency number 06221 387 7821 from mobile phones Please report all accidents to the conference officer at the registration desk In case of fire Press the nearest fire alarm button or the Emergency number 222 from any internal phone A loud fire alarm will go off if an evacuation is required On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting points Do not use the lifts Beyond first aid Please remember to bring your own medication if needed to the conference Note that the next pharmacy is a 4 minute drive from the EMBL but for many medications you will be required to see a doctor to get a prescription Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg In any case the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary Internet Wi Fi is available everywhere on the premises using the EMBL Events network and the event specific password which will be provided on site The eduroam network secure world wide roaming access service developed for the international research and education community is also available Lost and found Lost and Found are kept at the registration desk until the end of the conference Luggage There are lockers available on site to store your luggage which require a 2 EURO coin to operate There is another luggage room on level E0 which is free to use but remains unlocked during the conference Nursing room There is a nursing room available in the ATC Rooftop Lounge on level A29 Photography During the conference an EMBL Photographer may be taking photographs If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Printing We can help printing your boarding passes train ticket Please send it to events embl de and collect your print outs at the registration desk Room for prayer yoga and meditation There is a room for prayer mediation and yoga located on level E0 behind the Auditorium Please be respectful of other participants using the room Sightseeing A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing Travel to and from the venue During the event we provide conference shuttle buses to and from EMBL In addition there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time Information on the conference shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page Useful German expressions HelloHalloGoodbyeAuf WiedersehenGood morningGuten MorgenGood afternoonGuten TagGood eveningGuten AbendGood nightGute NachtI m sorryTut mir leidExcuse me Entschuldigen SieHow are you Wie gehts I m fine thanks And you Mir geht es gut danke und dir Ihnen What is your nameWie heisst du Wie heissen Sie My name isIch heisseDo you speak EnglishSprechen Sie Englisch I don t understandIch verstehe nichtPlease speak more slowlyK nnen Sie bitte langsamer sprechenThank youDankesch nWhere is the toilet Wo ist die Toilette Please call me a taxiBitte rufen Sie mir ein TaxiHow do I get to Wie komme ich zum zur A beer two beers pleaseEin Bier zwei Bier bitteA glass of red white wine pleaseEin Glas Rot Weisswein bitteThe menu pleaseDie Speisekarte bitteIs there a local speciality Gibt es eine Spezialit t aus dieser Gegend I m VegetarianIch bin VegetarierIt was deliciousEs war hervorragendThe bill pleaseDie Rechnung bitteI have a headacheIch habe KopfschmerzenI have a sore throatIch habe HalsschmerzenMy stomach hurtsIch habe MagenschmerzenI m allergic toIch bin allergisch gegenI need a doctor who speaks EnglishGibt es einen Arzt der Englisch spricht Virtual participation What s included Access to all the livestreamed talks Video library of the recorded talks during and after the event Facility to submit questions Please note that only on site participants are able to submit abstracts and participate in the poster sessions Event platform We are using an event platform for this conference More information about the platform will be shared ahead of the conference Guidelines Do not broadcast the conference to unregistered participants You are encouraged to tweet and post about the event Tweet unless the speaker specifically says otherwise but be mindful of unpublished data Please do not capture transmit or redistribute data presented at the meeting Additional information can be found in our Code of Conduct Health and well being It is important to stay healthy and move around especially when you are attending an event virtually We have put together a few coffee break stretches and yoga videos in the conference platform for you to enjoy during the event How to ask questions Please use the Q A function in the event platform If you have any other questions you can go to the Help Desk in the event platform Click on more on the top menu and click Help Desk Time zone The programme is planned based on the Europe Berlin time zone unless otherwise stated Please take your time zone into consideration when planning your attendance Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page COVID 19 related questions COVID 19 information for onsite events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Bronze sponsor Event sponsor Arraystar Inc Cell Research Event supporters Media partners Advanced Biology a Wiley Online Library Bio Essays a Wiley Online Library International Union of Biochemistry and Molecular Biology FEBS Journal a FEBS Press journal FEBS Letters a FEBS Press journal FEBS Open Bio a Febs Press journal Molecular Systems Biology an EMBO Press journal Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de About EMBO EMBL Symposia promote scientific communication and collaboration in the European research area They provide scientists with a platform to discuss and exchange ideas on forward looking topics and new developments in the life sciences Topics emphasise upcoming developments and the interdisciplinary nature of related fields Jointly funded and organised by EMBO and EMBL and complementary to their respective courses workshops and conference programmes the symposia promote scientific communication and collaboration All symposia are held in the EMBL Advanced Training Centre ATC in Heidelberg Germany or virtually Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9 Leaderboard 728 90...

Marc Bühler, Anna Eulálio, Joshua Mendell, Gisela Storz, Igor Ulitsky

EMBO | EMBL Symposium

EMBL Heidelberg, Virtual

10 October - 12 October 2023

Open Virtual Ensembl Browser Workshop

Edit

October 10, 2023 00:002023CourseVirtual

Description Work with the Ensembl Outreach team to get to grips with the Ensembl browser accessing gene variation comparative genomics and regulation data and mine these data with BioMart...

Benjamin Moore

Virtual

9 October - 13 October 2023

Liquid biopsies

Edit

October 09, 2023 00:002023CourseEMBL Heidelberg

Description OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview Please see EMBL s COVID 19 safety policy for testing and other requirements to attend this on site course Course Overview There is an increasing interest and need to analyse biomarkers in liquid biopsies including basic research and clinical applications Liquid biopsies have several advantages including being minimally invasive allowing repeated sampling and sampling is often clinical routine This course will provide an overview of the several techniques to detect and analyse liquid biopsy based analytes such as circulating tumour cells cell free tumor DNA ctDNA miRNA extracellular vesicles mRNA carbohydrates and proteins Participants will be introduced to all aspects ranging from proper sampling through analyte analysis and final data analysis Experimentally we will demonstrate ultrasensitive ctDNA analysis using sequencing and digital PCR In addition targeted miRNA profiling and flow cytometry with single cell analysis will be highlighted We will cover aspects of other analytes by lectures and we will have a strong focus on applications especially cancer applications Aspects of biobanking and clinical implementation will also be highlighted Audience This course targets scientists entering the field of liquid biopsy analysis and wanting to learn about the benefits and limitations of different approaches Modules Resources Ultra sensitive mutation detection using sequencing Flow cytometry and single cell analysis Digital PCR applications in the liquid biopsy workflow Hands on data analysis and interpretations Learning Outcomes Participants will receive an overview of various experimental workflows in liquid biopsies from sample preparation to data analysis The course provides an overview of current theories methods and emerging applications Whereby a strong focus will be on experimental design best practices pitfalls as well as dos and don ts After the course participants should be able to assess the best methods for their application as well as design their experiment What past participants say about the course This was a great course that has helped me understand the basics as well as gain in depth knowledge on liquid biopsies Simply phenomenal M A Bari Siddiqui All India Institute of Medical Sciences Speakers Speakers trainers and staff J rg Bantin Bio Rad Germany Anders Edsj Sk ne University Hospital Sweden Daniel Gimenes EMBL Heidelberg Germany Tony E Godfrey Boston University School of Medicine USA An Hendrix Ghent University Belgium Romy Kirsten University Hospital Mannheim Germany Mikael Kubista Institute of Biotechnology of the Czech Academy of Sciences Czech Republic Ulf Landegren Uppsala University Sweden Manuel Luna Santamar a Sahlgrenska Academy at University of Gothenburg Sweden Tobias sterlund Sahlgrenska University Hospital Sweden Hilal Ozgur EMBL Heidelberg Germany Kim Pettersson University of Turku Finland Michael Pfaffl Technical University of Munich Germany Beata Ramasz EMBL Heidelberg Germany Pia Scheu Bio Rad Germany Anders St hlberg University of Gothenburg Sweden Karin Sundfeldt University of Gothenburg Sweden Jessica Sutter EMBL Heidelberg Germany Val rie Taly Paris Descartes University France Scientific organisers Anders St hlberg University of Gothenburg Sweden Karin Sundfeldt University of Gothenburg Sweden Course organisers Sophie Dutzi Course and Conference Officer EMBL Heidelberg Germany Irena Provaznikova Training Lab Technician EMBL Heidelberg Germany Programme Got something to say Tweet it EMBLLiquidBiopsies Some pre course work such as watching pre recordings protocol reading and computational exercises with estimated time 0 10 hours will be required and will be shared in advance of the course Some speakers may need to join virtually to give their lecture or Q A and the programme is subject to change Day 1 Monday 9 October 2023 Time Europe Berlin ProgrammeLocation08 40 09 00Bus from hotel to EMBL ATC EntranceBus stop in front of ISG Hotel08 45 09 00RegistrationFlex Lab A B09 00 09 30Welcome and house notes and course overviewFlex Lab A B09 30 10 30Background SimSen protocol lectureAnders St hlberg Sahlgrenska Academy at University of Gothenburg SwedenKarin Sundfeldt University of Gothenburg SwedenFlex Lab A BFlexible Coffee BreakIn front of Training Lab Area10 30 12 00Practical session 1 DNA extraction Manuel Marceliano Luna Santa Mar a Sahlgrenska Academy at University of Gothenburg Sweden Hilal Ozgur EMBL Heidelberg Germany Jessica Sutter EMBL Heidelberg GermanyTraining Lab B12 00 13 00LunchEMBL Canteen13 00 14 30Practical session 2 SiMSen Seq library preparation Manuel Marceliano Luna Santa Mar a Sahlgrenska Academy at University of Gothenburg Sweden Hilal Ozgur EMBL Heidelberg Germany Jessica Sutter EMBL Heidelberg GermanyTraining Lab B14 30 15 00Coffee breakIn front of Training Lab Area15 00 16 30Ice breaker Flash talksFlex Lab A B16 30 17 00Q A session to pre recorded lectures Anders St hlberg Sahlgrenska Academy at University of Gothenburg SwedenFlex Lab A B17 00 18 30Practical session 3 SiMSen Seq Clean Up and quality controlManuel Marceliano Luna Santa Mar a Sahlgrenska Academy at University of Gothenburg Sweden Hilal Ozgur EMBL Heidelberg Germany Jessica Sutter EMBL Heidelberg GermanyTraining Lab B18 30 20 30Pizza and Poster Session 1ATC Helix B20 30Departure to HotelATC Entrance Day 2 Tuesday 10 October 2023 Time Europe Berlin ProgrammeLocation08 40 09 00Bus from hotel to EMBL ATC EntranceBus stop in front of ISG Hotel09 00 09 05Overview of the dayFlex Lab A B09 05 10 00Lecture Single Cell Sorting Beata Ramasz EMBL Heidelberg GermanyFACS Facility GeneCore FacilityFlexible Coffee BreakIn front of Training Lab Area10 00 12 00Practical session 4 Single Cell Sorting Beata Ramasz EMBL Heidelberg Germany Daniel Gimenes EMBL Heidelberg Germany GeneCore tourFACS Facility GeneCore Facility12 00 12 30Practical session 5 SiMSen Seq QCLibrary poolingAnders St hlberg Sahlgrenska Academy at University of Gothenburg SwedenHilal Ozgur EMBL Heidelberg GermanyJessica Sutter EMBL Heidelberg GermanyTraining lab B12 30 13 30LunchCanteen13 30 14 30Lecture Exosomal Biomarkers in Liquid Biopsies How to identify valid and better Biomarker Signatures from micro vesicular small RNA SequencingMichael Pfaffl Technical University of Munich GermanyFlex Lab A B14 30 15 00Practical session 6 Single cell RTManuel Marceliano Luna Santa Mar a Sahlgrenska Academy at University of Gothenburg Sweden Hilal Ozgur EMBL Heidelberg Germany Jessica Sutter EMBL Heidelberg GermanyTraining lab B15 00 16 00Lecture Introduction to ddPCRJ rg Bantin Bio Rad GermanyFlex Lab A B16 00 16 30Practical session 7 Single cell qPCRManuel Marceliano Luna Santa Mar a Sahlgrenska Academy at University of Gothenburg Sweden Hilal Ozgur EMBL Heidelberg Germany Jessica Sutter EMBL Heidelberg GermanyTraining lab B16 30 16 45Coffee breakIn front of Training Lab Area16 45 18 30Practical session 8 ddPCRJ rg Bantin BioRad GermanyPia Scheu Bio Rad GermanyTraining lab B18 30 19 30Practical session 9 PCR setup droplet generation and cyclingStart reading the experimentJ rg Bantin BioRad GermanyPia Scheu Bio Rad GermanyTraining lab B19 30 21 30Poster session 2 tapasATC Helix B21 30Departure to HotelATC Entrance Day 3 Wednesday 11 October 2023 Time Europe Berlin ProgrammeLocation08 40 09 00Bus from hotel to EMBL ATC EntranceBus stop in front of ISG Hotel09 00 09 15Overview of the dayFlex Lab A B09 15 11 15Practical session 10 Data analysis with QX Manager J rg Bantin BioRad Germany Pia Scheu Bio Rad GermanyFlex Lab A B11 15 11 30Coffee breakIn front of Training Lab Area11 30 12 30Lecture Role of biobanks in securing process quality in sample retrieval and storageRomy Kirsten University Hospital Mannheim GermanyFlex Lab A B12 30 13 30Technology lunchRooftop Lounge13 30 14 30Lecture Effect of pre analytical factors on the measurement of Evs in Liquid BiopsiesAn Hendrix Ghent University BelgiumFlex Lab A B14 30 15 30Title to be confirmedNayara Azevedo Roche GermanyFlex Lab A B15 30 16 00Coffee break and Course PictureIn front of Training Lab Area16 00 17 00Lecture Clinical validation of droplet based procedures in the context of liquid biopsiesValerie Taly Paris Descartes University FranceFlex Lab A B17 00Free evening17 00Departure to HotelIn front of ATC entrance17 30Bus to Neckarm nzplatzBus stop in front of ISG Hotel Day 4 Thursday 12 October 2023 Time Europe Berlin ProgrammeLocation08 40 09 00Bus from hotel to EMBL ATC EntranceBus stop in front of ISG Hotel09 00 09 15Overview of the dayFlex Lab A B09 15 10 15Lecture Europium nanoparticle based test concept for glycovariants of traditional and novel biomarkers to provide enhanced cancer specifictyKim Pettersson University of Turku FinlandFlex Lab A B10 15 10 45Coffee breakIn front of Training Lab Area10 45 11 45Lecture Protein detection in Liquid BiopsiesUlf Landegren Uppsala University SwedenFlex Lab A B11 45 12 45Poster group discussionFlex Lab A B12 45 13 45LunchEMBL Canteen13 45 14 45Lecture Diagnostic potential of tumor DNA in proximal fluids in gynecologic cancer Karin Sundfeldt Sahlgrenska Academy at University of Gothenburg SwedenFlex Lab A B14 45 16 00Lecture two tailed PCR Mikael Kubista Institute of Biotechnology and TATAA Biocenter Czech RepublicComputer Training Lab16 00 16 30Coffee breakIn front of Training Lab Area16 30 18 00Practical session 11 Single cell analysis Data analysis and complianceMikael Kubista Institute of Biotechnology of the Czech Academy of Sciences Czech RepublicComputer Training Lab18 00 18 30Departure to Hotel and DowntownIn front of ATC entrance18 30 19 30Free Time in the City Centre19 30 22 00Course dinner downtown Day 5 Friday 13 October 2023 Time Europe Berlin ProgrammeLocation08 40 09 00Bus from hotel to EMBL ATC EntranceBus stop in front of ISG Hotel09 00 09 15Overview of the dayFlex Lab A B09 15 10 15Lecture Liquid Biopsies in the clinical contextHigh fidelity sequencingTony E Godfrey Boston University School of Medicine USAFlex Lab A B10 15 10 30Coffee breakComputer Training Lab10 30 12 00Practical session 12 multivariate analysis Mikael Kubista Institute of Biotechnology and TATAA Biocenter Czech RepublicComputer Training Lab12 00 13 00LunchEMBL Canteen13 00 16 00Practical session 13 SiMSen Seq Data analysis Tobias sterlund and Manuel Marceliano Luna Santa Mar a Sahlgrenska Academy at University of Gothenburg SwedenComputer Training Lab16 00 16 30Coffee BreakComputer Training Lab16 30 17 30Lecture Implementing liquid biopsies in the clinic needs obstacles and possibilitiesAnders Edsj Sk ne University Hospital SwedenFlex Lab A B17 30 18 00Course wrap upFlex Lab A B18 00Departure to the HotelIn front of ATC entrance18 30DinnerISG Hotel Practical information Registration fees and motivation letter The course is limited to 16 participants For selection purposes please note that your application will not be considered without a letter of motivation Registration Registration fees include admission course materials COVID 19 safety measures meals and coffee breaks Academia 790PhD Student 790Industry 1200 A letter to support your visa application will be issued on request once payment of the registration fee is confirmed We recommend that you book your visa appointment as soon as possible to avoid any delay with your visa application Confirmation and payment The registration fee should be paid only after acceptance to the course The results will be announced approximately 2 3 weeks after the application deadline Motivation letter submission After you have logged in and successfully registered you will receive an email asking you to submit your motivation letter Click on the link provided and enter your motivation letter in the text box provided Alternatively you can submit your motivation letter by clicking on the link on the confirmation page directly after registering Instructions Include your relevant skills experience and qualifications showing why you would be suitable for the course Explain why you would like to attend including what you can contribute and how you think you will benefit from the course Please note The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised For detailed instructions please watch our video on how to submit a course motivation letter Further details For further information about registration and motivation letter submission please refer to the FAQ page Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of both registration fee waivers and travel grants Availability is limited to participants attending on site EMBL Courses and virtual or on site EMBO Practical Courses in Heidelberg and will be indicated during the motivation letter submission process Your place in the course is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course Travel grant The travel grant will cover the cost of travel airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Course within Europe up to 1000 for participants travelling to an EMBL Course from outside Europe up to 500 for any participant travelling to an EMBO Practical Course up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Practical Course up to 700 for any participant working in Croatia Czech Republic Estonia Greece Hungary Italy Lithuania Luxembourg Poland Slovenia and Turkey travelling to an EMBO Practical Course Registration fees are only covered for EMBO Practical Courses The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant EMBO Practical Courses only For EMBO Practical Course participants with children there is the possibility to apply for a childcare grant to offset child care costs incurred by participants or speakers when participating at a course Eligible costs include fees for a babysitter or child care facility travel costs for a caregiver or travel costs for taking the child to the meeting etc Please note that priority will be given to early stage researchers A maximum amount of 500 can be awarded per participant applying for an EMBO childcare grant Boehringer Ingelheim Fonds travel grant Applies to selected courses only Availability will be indicated during the motivation letter submission process This grant covers costs related to your attendance at the course registration travel and accommodation costs The grant is restricted to PhD students and postdocs who conduct basic biomedical research Whether you are eligible to apply for a travel grant depends on when you received your university entrance qualification e g Abitur A Levels High School Diploma Final State Examination for PhD and MD students as well as graduates the university entrance qualification must not have been obtained more than 11 years ago at the time of the envisaged course for postdocs the university entrance qualification must not have been obtained more than 13 years ago at the time of the envisaged course Application You may apply for financial assistance when submitting your motivation letter for courses In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application For the Boehringer Ingelheim Fonds Travel Grant there is a pre application question during the motivation letter submission process and if selected you will be requested to complete a standard form and documentation consisting of your travel expense estimation Selection The scientific organisers will select the recipients of all financial assistance during the motivation letter selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the course Selection is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details See our list of external funding opportunities and for further information about financial assistance please refer to the FAQ page Accommodation and shuttles Hotel Single rooms have been reserved for 5 nights 9 14 October 2023 at the ISG Hotel After the selection process selected participants should contact the hotel directly to make a booking booking code LIQ23 01 We recommend that all course participants stay at the ISG Hotel which is the dedicated hotel for the course Local transport Shuttle buses will go from the ISG Hotel to EMBL and back mornings and evenings A bus schedule and location of the bus stops will be made available prior to the meeting Further details Address EMBL Heidelberg Meyerhofstra e 1 69117 Heidelberg GermanyFor further information on getting to EMBL Heidelberg visit our Travel Information page For enquiries about accommodation and local transportation please refer to the FAQ page Technical requirements and event software Event software The EMBL eCampus learning platform will be used to collaborate communicate and network with all of the course participants All participants will receive information on how to join shortly before the course We recommend using Chrome Safari or Mozilla Firefox browsers for eCampus Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page COVID 19 related questions COVID 19 information for on site events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Course partners Course sponsors Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other events or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9...

Anders Ståhlberg, Karin Sundfeldt

EMBL Course

EMBL Heidelberg

9 October - 13 October 2023

Metagenomics bioinformatics at MGnify

Edit

October 09, 2023 00:002023CourseEMBL-EBI

Description Overview Learn about the tools processes and analysis approaches used by MGnify in the field of genome resolved metagenomics This course will cover the use of publicly available resources to manage share analyse and interpret metagenomics data focussing primarily on the assembly based approaches used in MGnify analysis The delivered content will involve participants learning via live lectures and presentations followed by live Q As with the trainers Practical experience will be developed in group activities and in computational exercises run using containerised tools on our training infrastructure...

Meredith Willmott

EMBL-EBI

5 October 2023

Poster winners, PerMedCoE Summer School 2023

Edit

October 05, 2023 15:052023WebinarVirtual

Description This special edition of the PerMedCoE webinar series features speakers who were awarded poster prizes at the PerMedCoE Summer School 2023 Find out more about our speakers and their research Towards Tailored Cancer Therapies Robust platform for drug testing in patient specific Boolean models Viviam Berm dezComputational modelling of High Grade Serous Ovarian Cancer HGSOC Marco Fari asDissecting cellular communication in the tumour microenvironment through multiscale dynamical modelling Malvina MarkuAbout the speakerViviam Berm dez is a PhD candidate at the Norwegian University of Science and Technology specialising in Boolean models Her academic journey began in general biology back in her home country Venezuela at Sim n Bol var University Then she hopped over to Norway for a one year student exchange where she unexpectedly found herself staying longer to complete a master s degree in molecular cell biology diving deep into systems biology and cell modelling Now in her Computational Cancer Biology PhD she combines machine learning and modelling to address complex challenges of precision medicine Beyond her coding skills she also has green fingers so she finds peace caring for her plants during her free time Looking ahead she aspires to contribute to the field of precision medicine through her PhD project and continue exploring the fascinating world of digital twins without forgetting the ethical side of things Marco Fari as originally from Ponferrada in north western Spain is an enthusiastic nature lover who enjoys spending free time outdoors His academic journey began with a Bachelor s degree in Biology at the Complutense University of Madrid Following his interest for cellular and molecular biology he moved to Trondheim Norway where he pursued a Master s degree at the Norwegian University of Science and Technology NTNU During this period Marco did his thesis focusing on Boolean modelling of macrophage polarisation and its relevance to acute COVID 19 This research was conducted under the guidance of Martin Kuiper within the DrugLogics group Following the completion of the Master s program Marco moved to Barcelona and joined Marta Cascante s research group at Barcelona University There he delved into the intricate metabolic alterations triggered by SARS CoV 2 infection In his latest pursuit Marco returned to Trondheim to start his PhD journey at NTNU under the supervision of Kaisa Lehti His research leverages Boolean modelling to explore the dynamics of the tumour microenvironment and its influence on the aggressiveness of high grade serous ovarian cancer Malvina Marku studied her undergraduate degree in Physics at the University of Tirana Albania where she pursued her MSci project in the field of Nonlinear Dynamics studying the qualitatively universal behaviour of recursive systems As a PhD student on Computational Physics at the University of Tirana her PhD thesis focused on mathematical modelling of regulatory networks and inference methods of network reaction rates She joined Pancaldi s lab at the Cancer Research Center of Toulouse as a postdoc where she is currently working on multi scale dynamical modelling of the tumour microenvironment The research is focused on Chronic Lymphocytic Leukaemia CLL microenvironment and the crucial role of the cancer cell immune cell interaction in defining the cancer cell survival Her main interest is in applying dynamical modelling and networks theory to study the dynamics and emerging behaviour of complex biological systems and to gain a deeper understanding of systems evolution from the molecular network perspective She is interested in using computational models that are able to capture emerging biological behaviour and evolving patterns in spatially structured tumours for enabling more accurate and clinically relevant predictions regarding disease course and treatment outcome...

Viviam Bermúdez, Marco Fariñas, Malvina Marku

Virtual

4 October 2023

Studying genes and genomes with Ensembl genome browser

Edit

October 04, 2023 15:302023WebinarVirtual

Description The Ensembl genome browser provides data on genes variants comparative genomics and gene regulation for over 300 species Its sister project Ensembl Genomes www ensemblgenomes org consists of five sub portals bacteria fungi protists plants and invertebrate metazoa which contain data for over 2 000 eukaryotic including wheat barley tomato and brassicas and over 30 000 prokaryotic genomes This webinar will provide the participants with an introduction on how to use the Ensembl genome browser navigate the website and export data...

Virtual

4 October - 7 October 2023

Seeing is believing: imaging the molecular processes of life

Edit

October 04, 2023 00:002023ConferenceEMBL Heidelberg, Virtual

Description OverviewSpeakersProgrammePractical informationSponsorsAboutMedia kitPre conference workshopsLunch workshops Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Symposium overview The molecular processes of life are naturally dynamic in space and time from the atomic to the organismal level The rapid development of imaging methods across the full scale of biological organisation is revolutionising our ability to visualise the inner workings of macromolecular complexes organelles cells tissues organs and whole organisms Being able to see biological processes unfold in real time allows us to understand the mechanisms of life as well as disease The symposium will bring together the leading developers of imaging methods with cutting edge applications that illustrate how imaging can answer biological questions We will emphasize methods that can capture the dynamics of life spanning the whole range from molecular resolution to imaging of whole organisms From its beginning in 2011 Seeing is Believing has embraced novel imaging technologies that open new windows for biological discovery including single molecule and super resolution light sheet and correlative light electron microscopy The symposium provides many opportunities for presentations discussions and interactions between students postdocs junior and senior investigators Session topics Imaging structure and function of single molecules in situ Tissue and organoid imaging Probes biosensors Organismal and intravital imaging Image analysis modelling New approaches to imaging What past participants say about the symposium This conference was very well organised great talks and exciting new tools and techniques were presented I am very happy I attended Highly recommend for everybody interested in microscopy Alina Gavrilov Hoffmann La Roche Switzerland The EMBL symposium was well organised and executed The combination of field expert talk and technical field talk made researchers very much aware about subject research and available advance imaging facility and their applications Dr Vijay K Verma Dept of Microbiology University of Delhi South Campus India I was happy to attend this amazing meeting full of talks showing incredible combinations of the most recent state of the art techniques some of which even looked like being from far future or sci fi Marketa Schmidt Cernohorska Max Perutz Labs Vienna Austria Seeing Is Believing maybe you have to see it to believe me how AMAZING this conference is Three days filled with the latest around microscopy biology and data analysis presented by the big names and the young but rising stars A delight Florian Jug Fondazione Human Technopole ItalyPlease see EMBL s COVID 19 safety recommendations if attending the on site event Speakers Speakers Ibrahim Ciss Max Planck Institute of Immunobiology and Epigenetics Germany Lucy Collinson Francis Crick Institute UK Qionghai Dai Tsinghua University China Xavier Darzacq University of California Berkley USA Meghan Driscoll University of Minnesota USA Jan Ellenberg EMBL Heidelberg Germany Sebastian Eustermann EMBL Heidelberg Germany Ronald Germain National Institute of Allergy and Infectious Diseases USA Anna Kreshuk EMBL Heidelberg Germany Jennifer Lippincott Schwartz HHMI Janelia Research Campus USA Ons M Saad Panluminate USA Satyajit Mayor National centre for Biological Sciences India Atsushi Miyawaki RIKEN Center for Brain Science Japan Jonas Ries EMBL Heidelberg Germany Loic Royer Chan Zuckerberg Biohub USA Andrej Sali University of California San Francisco USA Erdinc Sezgin SciLifeLab Sweden Marvin Tanenbaum Hubrecht Institute The Netherlands Aubrey Weigel Janelia Research Campus USA Scientific organisers Jan Ellenberg EMBL Heidelberg Germany Jennifer Lippincott Schwartz HHMI Janelia Research Campus USA Satyajit Mayor National centre for Biological Sciences India Atsushi Miyawaki RIKEN Center for Brain Science Japan Conference organisers Iva Gavran Course and Conference Officer EMBL Heidelberg Germany Programme Got something to say Tweet it EESImaging For registered participants recorded talks will be accessible on demand for 2 weeks after the end of the event unless indicated otherwise Programme is subject to change Day 1 Wednesday 4 October 2023 Time Europe Berlin Speaker10 45 11 30Registration for workshop participants11 30 12 30Industry pre conference workshops registration required 11 30 13 00Registration and light refreshments13 00 13 15Opening remarksSession 1 Imaging structure and function of single molecules in situChaired by Xavier Darzacq University of California Berkley USA13 15 13 35Super resolution imaging of transcription in living cellsIbrahim Ciss Max Planck Institute of Immunobiology and Epigenetics Germany13 35 13 55Single molecule tracking using proximity assisted photoactivation to study the dynamics of proteins engaged in multiple macromolecular assembliesXavier Darzacq University of California Berkley USA13 55 14 15Exploring the principles of energy driven chromatin organisationSebastian Eustermann EMBL Heidelberg Germany14 15 14 35Localization influences macromolecular complex composition Origin of Nuclear Pore Complex AsymmetryJenny Sachweh Max Planck Institute of Biophysics Germany14 35 14 55Studying viral infection dynamics and heterogeneity using single molecule microscopyMarvin Tanenbum Hubrecht Institute The Netherlands14 55 15 40Coffee Break in Foyer and Meet the invited speakers in the CTY Foyer with Ibrahim Ciss Xavier Darzacq Sebastian Eustermann and Marvin Tanenbumkindly sponsored by ATTO TEC15 40 16 00Direct observation of motor protein stepping in living cells using MINFLUXJonas Ries EMBL Heidelberg Germany16 00 16 20Motion of single VAPB molecular tethers reveals a metastable structure at ER mitochondria contact sitesChris Obara HHMI Janelia Research Campus USA16 20 16 40Mitochondria move via distinct transport modesJulius Winter EPFL Switzerland16 40 17 00Measuring biophysical properties of cells and bioparticles in health and diseaseErdinc Sezgin Karolinska Institutet Sweden17 00 17 20Unveiling the ultrastructural landscape of native extracellular matrix via lift out cryo FIB and cryo ETBettina Zens Institute of Science and Technology Austria Austria17 20 19 00Poster Sneak peek session 19 00 20 30Conference dinner20 30 22 00Poster Sneak peek session continued Day 2 Thursday 5 October 2023 Time Europe Berlin SpeakerSession 2 Tissue and organoid imagingChaired by Jennifer Lippincott Schwartz HHMI Janelia Research Campus USA09 00 09 20Uncovering brain tissue architecture with super resolution light microscopyJohann Danzl Institute of Science and Technology Austria AustriaNot available on demand09 20 09 40Automated live cell single molecule imaging reveals the molecular dynamics of overexpressed Sox9 associated with a cancerous state transition in intestinal organoidsNike Walther University of California Berkeley USANot available on demand09 40 10 00Imaging of cancer cell dynamics in vitro and in situ from a whole organism to subcellular imaging with self driving multi scale microscopyStephan Daetwyler UT Southwestern Medical Center USA10 00 10 45Coffee Break and Meet the editors in ATC FoyerMeet the speakers in CTY Foyer with Jonas Ries and Erdinc Sezginkindly sponsored by ATTO TEC10 45 11 05Open top dual view light sheet microscope for live imaging of large multicellular systems in multi well formatFranziska Moos Friedrich Miescher Institute Switzerland11 05 11 25Exploring life across scales with volume correlative light and electron microscopyLucy Collinson Francis Crick Institute UK11 25 11 45Do synaptic like mechanisms control insulin secretion in pancreatic cells Kylie Dang University of Sydney Australia11 45 12 05Investigating the spatial distribution dynamics and regulation of translation of mRNAs encoding secretory and membrane proteins by single molecule trackingJennifer Lippincott Schwartz HHMI Janelia Research Campus USA12 05 14 05Lunch break Lunch workshop by Thermo Fisher Scientific12 35 13 35 Courtyard Room AEMBL Imaging centre tours sign in sheets at the registration desk Meeting point registration deskPlease be there a few minutes before the start of tour12 15 12 55 Tour 113 05 13 45 Tour 2Session 3 Probes biosensorsChaired by Atsushi Miyawaki RIKEN Center for Brain Science Japan14 05 14 25Sensitized acceptor anisotropy with dim fluorescent donor to monitor FRET induced angular displacementHideaki Mizuno KU Leuven Belgium14 25 14 45Highly specific and non invasive imaging of Piezo1 dependent activity across scales using GenEPiKonstantinos Kalyviotis Imperial College London UK14 45 15 05Chemigenetic kinase biosensors for multiplexed activity sensing and super resolution imagingMichelle Frei University of California San Diego USANot available on demand15 05 15 50Coffee Break and Meet the editors in ATC FoyerMeet the speakers in CTY Foyer with Lucy Collinson and Jennifer Lippincott Schwartz kindly sponsored by ATTO TEC15 50 16 10Colors by Shape EMcapsulins as multi channel gene reporters for Electron Microscopy and correlative imaging modalitiesGil Westmeyer Technical University of Munich Germany16 10 16 30Chemically programmable bacterial probes for the recognition of cell surface proteinsLeila Motiei Weizmann Institute of Science IsraelNot available on demand16 30 16 50A locally activatable sensor for robust quantification of organellar GSHSarah Emmert University of Z rich Switzerland16 50 17 10Continuity in space and timeAtsushi Miyawaki RIKEN Center for Brain Science Japan17 10 17 40Flash talksPoster numbers odd 63 85 91 109 147 149 155 157 161 163 173 185 195 197 209 21117 40 19 10Poster Session 1 odd with beer and snacks19 10 20 30Conference dinner20 30 22 30Pub quiz in the Canteen Day 3 Friday 6 October 2023 Time Europe Berlin SpeakerSession 4 Organismal intravital imagingChaired by Jan Ellenberg EMBL Heidelberg Germany09 00 09 20Imaging the structure and mechanism of mitotic chromosome folding in human cells and mouse embryosJan Ellenberg EMBL Heidelberg Germany09 20 09 40Programmed disassembly of an Interplanar Amida Network coordinates 3D epithelial growthOsamu Shimmi University of Helsinki Finland09 40 10 00Zebrahub Multimodal Zebrafish Developmental Atlas Reveals the State Transition Dynamics of Late Vertebrate Pluripotent Axial ProgenitorsLoic Royer Chan Zuckerberg Biohub USA10 00 10 45Coffee Break in Foyer and Meet the invited speakers in the CTY Foyer with Lin Tian Atsushi Miyawaki Jan Ellenberg and Loic Royer kindly sponsored by ATTO TEC10 45 11 05Highly Multiplex 2D and 3D Imaging Methods and Analytical Tools for Probing Cell Organization and Function in Complex Tissue SettingsRonald Germain National Institute of Allergy and Infectious Diseases NIH USANot available on demand11 05 11 25Deep Brain Tumor Imaging Through Customized Three Photon Microscopy and AnalysisVarun Venkataramani University Heidelberg GermanyNot available on demand11 25 11 45High resolution line scan Brillouin microscopy for live imaging of mechanical properties during embryo developmentCarlo Bevilacqua EMBL Heidelberg Germany11 45 12 05Computational intravital fluorescence mesoscopyQionghai Dai Tsinghua University ChinaNot available on demand12 05 14 05Lunch break Lunch workshop by BD Life Sciences12 35 13 35 Courtyard Room AEMBL Imaging centre tours sign in sheets at the registration desk Meeting point registration deskPlease be there a few minutes before the start of tour12 15 12 55 Tour 313 05 13 45 Tour 4Session 5 Image analysis modellingChaired by Meghan Driscoll University of Minnesota USA14 05 14 25Life in the cytoplasm computational microscope captures in cell protein dynamicsTaras Pogorelov University of Illinois Urbana Champaign USANot available on demand14 25 14 45From integrative structural biology to cell biologyAndrej Sali University of California San Francisco USA14 45 15 05Exploring the universe of sub and multicellular organizationAubrey Weigel Janelia Research Campus HHMI USA15 05 15 50Coffee Break in Foyer and Meet the invited speakers in the CTY Foyer with Ronald Germain Qionghai Dai Andrej Sali and Aubrey Weigelkindly sponsored by ATTO TEC15 50 16 10Image analysis from the perspective of the 3D cell surfaceMeghan Driscoll University of Minnesota USA16 10 16 30Learning to explore phenotypesAnna Kreshuk EMBL Heidelberg Germany16 30 16 50Deciphering the randomness of lineage decisions in early developing mouse embryosGesa Loof Aix Marseille Universit France16 50 17 10ultrack large scale versatile cell tracking in Python under segmentation uncertaintyJordao Bragatani Chan Zuckerberg Biohub USA17 10 17 40Flash talksPoster numbers even 58 76 108 128 140 166 182 192 200 204 210 21817 40 19 10Poster Session 2 even with beer and snacks19 15Bus departures to Heidelberg Castle please show your dinner ticket when entering the bus and the castle 19 30Bus departures downtown for free evening 19 45 01 00Conference dinner and Party at the Heidelberg castle dinner ticket holders only or Free evening Day 4 Saturday 7 October 2023 Time Europe Berlin SpeakerSession 6 New approaches to imagingChaired by Satyajit Mayor National Centre for Biological Sciences India09 30 09 50 ngstr m resolution fluorescence microscopyIsabell Baudrexel Max Planck Institute of Biochemistry Germany09 50 10 10DNA tracing reveals the nanoscale organization of chromatin loops and domainsKai Beckwith Norwegian University of Science and Technology Norway10 10 10 30HiExM high throughput expansion microscopy enables scalable super resolution imagingJohn Day Massachusetts Institute of Technology USA10 30 11 15Coffee Break in Foyer and Meet the invited speakers in the CTY Foyer with Meghan Driscol Anna Kreshuk Ons M Saad and Satyajit Mayorkindly sponsored by ATTO TEC11 15 11 35 pan OptiX Illuminating the Nanostructural Landscape of Tissues and Cells for Precision MedicineOns M Saad Panluminate USA11 35 11 55Single molecule peptide identification using fluorescence blinking fingerprintsSalome P ntener University of Z rich Switzerland11 55 12 15Examining virus cell interactions via confocal iSCAT microscopyVahid Sandoghdar Max Planck Institute for the Science of Light Germany12 15 12 35Imaging the living cell membrane bilayer leaflet by leafletSatyajit Mayor National Centre for Biological Sciences IndiaNot available on demand12 35 12 50Closing Remarks and Poster Prize12 50 13 20Packed Lunch and departure13 20Shuttle bus to downtown13 30Shuttle bus to Frankfurt airport tickets sold at reception Practical information Registration fees and abstract submission On site registration fees include admission conference materials meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Virtual registration fees include access to all of the talks livestreamed and on demand and facility to submit questions On site Academia 700On site PhD Student 600On site Industry 900Virtual Academia 200Virtual PhD Student 150Virtual Industry 250 A letter to support your visa application will be issued on request once payment of the registration fee is confirmed We recommend that you book your visa appointment as soon as possible to avoid any delay with your visa application Accredited journalists may be eligible to register for complimentary press registration Registrants may be required to provide accreditation or equivalent proof of press membership after registration Please contact Iva Gavran for more information Please note that we do not offer complimentary registrations for editors of scientific journals Confirmation and payment Registration will be on a first come first served basis Your place can only be confirmed after payment of the registration fee If you are added to our waiting list please consider taking advantage of our offerings to participate virtually On site participants Types of payments accepted are international bank transfers and credit card payments Virtual participants We are only able to accept card payments In exceptional cases we can accept bank transfers Please contact events embl de for details Abstract submission Only participants registering to attend the on site event are eligible to submit an abstract Abstracts will not be accepted from virtual participants After registration you can submit your abstract via a separate link that will be provided in the email confirmation Alternatively you can access the link on the confirmation page directly after registering The same login credentials are used for both processes Please note Abstract body The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised Title The title should not exceed 20 words Only the first word of the title should start with a capital letter and the rest should be lowercase Authors and affiliations Please fill in the author s details as requested in the online form The compulsory fields are First Name Last Name Organisation Name Affiliation or Company Country and Email Kindly mark only one author in the role of First Author and please don t forget to indicate who will be the Presenter Please enter your co authors correctly via the system by adding accounts together with their organisation institute Do not copy paste them into the body of the abstract text as they will not be indexed in the abstract book Presentation types When submitting your abstract you can apply for an oral or poster presentation A selection process will take place with the results announced 2 3 weeks after the abstract submission deadline For detailed instructions on how to submit a conference abstract follow the instructions provided in this video Please check our FAQs pages for further information on how to submit an abstract Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of both registration fee waivers and travel grants These are available for on site participants at EMBL Conferences and EMBO EMBL Symposia and for on site and virtual participants at EMBO Workshops We are currently working on securing funding for all virtual participants and ask that you please apply for financial assistance for both on site and virtual participation Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course or conference Travel grant The travel grant will cover the cost of travel to an on site event airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from within Europe up to 1000 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from outside Europe up to 500 for any participant travelling to an EMBO Workshop up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Workshop up to 700 for any participant working in Croatia Czech Republic Estonia Greece Hungary Italy Lithuania Luxembourg Poland Slovenia and Turkey travelling to an EMBO Workshop Registration fees are only covered for EMBO Workshops The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Application On site participants You may apply for financial assistance when submitting your abstract In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Virtual participants If you are attending virtually you can apply for financial assistance in the submission portal by the abstract deadline Read the instructions on how to apply for financial assistance Only submissions for financial assistance will be accepted Presentation abstracts cannot be submitted here and will be declined In your application you will be asked to summarise your current work answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Selection The scientific organisers will select the recipients of all financial assistance during the abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details View our list of external funding opportunities and information on attending a conference as an event reporter For further information about financial assistance please refer to the FAQ page Accommodation and shuttles Accommodation is not included in the conference registration fee As further changes in our events are possible you should book flights trains and hotels with flexible options and favourable cancellation conditions The hotels below have rooms on hold for participants until Wednesday 6 September 2023 in some cases at special rates Please email the hotel directly quoting the booking code EES23 09 to confirm the exact price of the room Hotel AnlageHotel ibis HeidelbergHotel MonptiB B HotelISG Hotel Premier Inn Heidelberg CityExzellenz HotelLeonardo Hotel Heidelberg City CentreStaycity Aparthotel HeidelbergHotel Holl nder Hof Meininger HeidelbergHotel Vier Jahreszeiten Heidelberg Conference shuttle buses Conference shuttle buses are free of charge for participants and depart from designated bus stops near the hotels to EMBL and back mornings and evenings Conference bus shuttle schedule The bus stops for this conference are Hotel Staycity Speyerer Str 7 Kurf rsten Anlage Opposite Main Train Station Hotel Premier Kurf rsten Anlage 23 Leonardo Hotel Heidelberg City Center Bergheimer Str 63 Neckarmuenzplatz Heidelberg Tourist Information Peterskirche Bus stop in front of Monpti hotel ISG Hotel Im Eichwald 19 View Conference shuttle bus stops and hotels in a larger map Please note that not every bus stop will be used for every event Further details Address EMBL Meyerhofstra e 1 69117 Heidelberg Germany For further information on getting to EMBL Heidelberg visit Public Transportation to the Venue For information about accommodation and local transportation please refer to the FAQ page Onsite information Catering All meals and coffee breaks are included in the registration fee Our catering staff will prepare a wide variety of vegetarian meals meat and fish dishes soups pasta fresh fruit and vegetables as well as a variety of desserts Please wear your badge at all times when serving yourself No food or drinks are allowed in the auditorium Charging lockers There are lockers available next to the stairs leading down into the Auditorium You will find some of those equipped with sockets to charge your smartphone tablet etc Electricity and charging station In most places the electricity is 220 volts AC 50 cycles An adaptor and a plug that fits the German socket may be needed for your appliances laptop i e American Japanese etc A USB charging station for electronic devices is available at the registration desk EMBL merchandise If you are interested in purchasing an EMBL souvenir products presented in the glass display in the registration area please ask at the registration desk for more information Health and safety notes Please read EMBL s COVID 19 safety policy for on site events Do not smoke in any EMBL building Eating and drinking is prohibited in the Auditorium and all laboratories Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required The first aid room is located next to the ATC Registration Desk room 10 205 Dial the Emergency number 222 from any EMBL internal phone only Where is the accident What happened How many injured Emergency number 06221 387 7821 from mobile phones Please report all accidents to the conference officer at the registration desk In case of fire Press the nearest fire alarm button or the Emergency number 222 from any internal phone A loud fire alarm will go off if an evacuation is required On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting points Do not use the lifts Beyond first aid Please remember to bring your own medication if needed to the conference Note that the next pharmacy is a 4 minute drive from the EMBL but for many medications you will be required to see a doctor to get a prescription Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg In any case the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary Internet Wi Fi is available on campus using the EMBL Events network and the event specific password which will be provided on site The eduroam network secure worldwide roaming access service developed for the international research and education community is also available Lost and found Lost and Found items are kept at the registration desk until the end of the conference Luggage There are lockers available on site to store your luggage which require a 2 EURO coin to operate There is another luggage room on level E0 which is free to use but remains unlocked during the conference Nursing room There is a nursing room available in the ATC Rooftop Lounge on level A29 Photography During the conference an EMBL Photographer may be taking photos If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Printing We can help to print your boarding pass train ticket Please send it to events embl de and collect your print outs at the registration desk Room for prayer yoga and meditation There is a room for prayer meditation and yoga located on level E0 behind the Auditorium Please be respectful of others using the room Sightseeing A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing Travel to and from the venue During the event we provide conference shuttle buses to and from EMBL In addition there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time Information on the conference shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page Useful German expressions HelloHalloGoodbyeAuf Wiedersehen formal Tsch ss informal Good morningGuten MorgenGood afternoonGuten TagGood eveningGuten AbendGood nightGute NachtI m sorryEs tut mir leidExcuse me Entschuldigen SieHow are you Wie gehts I m fine thanks And you Mir geht es gut danke Und Dir Ihnen What is your nameWie hei en Sie formal Wie hei t du informal My name is Ich hei e Do you speak EnglishSprechen Sie englisch I don t understandIch verstehe nichtPlease speak more slowlyK nnen Sie bitte langsamer sprechenThank youDankesch nWhere is the toilet Wo ist die Toilette Please call me a taxiBitte rufen Sie mir ein TaxiHow do I get to Wie komme ich zum zur A beer two beers pleaseEin Bier zwei Bier bitteA glass of red white wine pleaseEin Glas Rot Wei wein bitteThe menu pleaseDie Speisekarte bitteIs there a local speciality Gibt es eine Spezialit t aus dieser Gegend I m VegetarianIch bin VegetarierIt was deliciousEs war hervorragendThe bill pleaseDie Rechnung bitteI have a headacheIch habe KopfschmerzenI have a sore throatIch habe HalsschmerzenMy stomach hurtsIch habe MagenschmerzenI m allergic toIch bin allergisch gegenI need a doctor who speaks English Ich brauche einen Arzt der englisch spricht Virtual participation What s included Access to all the livestreamed talks Video library of the recorded talks during and after the event Facility to submit questions Please note that only on site participants are able to submit abstracts and participate in the poster sessions Event platform We are using an event platform for this conference More information about the platform will be shared ahead of the conference Guidelines Do not broadcast the conference to unregistered participants You are encouraged to tweet and post about the event Tweet unless the speaker specifically says otherwise but be mindful of unpublished data Please do not capture transmit or redistribute data presented at the meeting Additional information can be found in our Code of Conduct Health and well being It is important to stay healthy and move around especially when you are attending an event virtually We have put together a few coffee break stretches and yoga videos in the conference platform for you to enjoy during the event How to ask questions Please use the Q A function in the event platform If you have any other questions you can go to the Help Desk in the event platform Click on more on the top menu and click Help Desk Time zone The programme is planned based on the Europe Berlin time zone unless otherwise stated Please take your time zone into consideration when planning your attendance Additional information Please find additional information including FAQs terms and conditions and travelling to EMBL on our Information for participants page Sponsors Platinum Sponsor Gold Sponsors Silver Sponsors Bronze Sponsors Event sponsors Abberior Instruments ASI Applied Scientific Instrumentation ATTO TEC BD Life Sciences Biosciences Chip NanoImaging DECTRIS AG MicroscopeHeaters com Hamamatsu Photonics H BNER Photonics Interherence Nikon Europe BV PicoQuant SmarAct GmbH tebu bio GmbH Event supporters Media partners EMBO reports an EMBO Press journal International Union of Biochemistry and Molecular Biology Journal of Cell Science a The Company of Biologists journal Open Biology a Royal Society journal Bio Essays a Wiley Online Library Advanced Biology a Wiley Online Library Imaging and Microscopy a Wiley Journal PLOS Biology a PLOS journal Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de About EMBO EMBL Symposia promote scientific communication and collaboration in the European research area They provide scientists with a platform to discuss and exchange ideas on forward looking topics and new developments in the life sciences Topics emphasise upcoming developments and the interdisciplinary nature of related fields Jointly funded and organised by EMBO and EMBL and complementary to their respective courses workshops and conference programmes the symposia promote scientific communication and collaboration All symposia are held in the EMBL Advanced Training Centre ATC in Heidelberg Germany or virtually Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 x 9 Leaderboard 728 x 90 Pre conference workshops For on site participants only The following industry workshops will be hosted by the sponsors of EMBO EMBL Symposium Seeing is believing imaging the molecular processes of life prior to the start of the event High throughput light sheet microscopy for delicate and large samples and how to handle the data by Felix WELTZIEN Luxendo GmbH Bruker Fluorescence Microscopy Room Helix B01 Simultaneous multicolor quantitative and auto calibrated TIRF imaging with the new Abbelight TIRF solution by Ipek Altinoglu Abbelight and Buelent Peker EVIDENT Europe Room Flexlab B Rare event detection with Autonomous Microscopy powered by Aivia and Coral Life workflow for Live Cell CLEM by J rgen Reymann and Robert Kirmse Leica Microsystems Room Flexlab A Untying your hands Using optical tweezers to go beyond just imaging by Emma Verver LUMICKS Room Court Yard Room B A benchtop super resolution platform for single molecule imaging and analysis by Ricardo Bastos ONI Room Helix A01 Add a new dimension to live imaging Use your Airyscan detector and uncover spatial molecular dynamics in your current samples by Dr Annette Bergter Carl Zeiss Microscopy GmbH Room Court Yard Room A on Wednesday 4 October 2023 11 30 12 30 In order to read the abstract of each workshop please click on the corresponding links above Participation in this workshop is free of charge for registered on site conference attendees The available place is limited first come first served All registered conference attendees will receive an email with a registration link shortly All pre conference workshops will take place simultaneously therefore please choose the one you would be interested in the most Lunch workshops For on site participants only The following lunch workshops will be hosted by the sponsors of EMBO EMBL Symposium Seeing is believing imaging the molecular processes of life will prior to the start of the event Image acquisition and analysis solutions for volume EM and cryo tomography by Alex Rigort and Maximilian Voll Thermo Fisher Scientific on Thursday 5 October 12 35 13 35 Room Court Yard Room A BD FACSDiscover S8 Cell Sorter See what you sort and sort what you see with BD CellView and BD SpectralFX Technologies by Tim Schenkel BD Life Sciences Biosciences on Friday 6 October 12 35 13 35 Room Court Yard Room A In order to read the abstract of each workshop please click on the corresponding links above Participation in this workshop is free of charge for registered on site conference attendees The available place is limited first come first served All registered conference attendees will receive an email with a registration link shortly...

Jan Ellenberg, Jennifer Lippincott-Schwartz, Satyajit Mayor, Atsushi Miyawaki

EMBO | EMBL Symposium

EMBL Heidelberg, Virtual

2 October - 6 October 2023

Structural bioinformatics

Edit

October 02, 2023 00:002023CourseEMBL-EBI

Sophie Spencer

EMBL-EBI

2 October - 4 October 2023

Signaling through Chromatin: from molecules to ecosystems

Edit

October 02, 2023 00:002023Public EventOther

Description If you are not redirected please visit the event website...

Symposium

Other

27 September 2023

Nucleotide sequencing data submission and retrieval at the ENA

Edit

September 27, 2023 15:302023WebinarVirtual

Description The European Nucleotide Archive ENA is an open access supported platform for the management sharing integration archiving and dissemination of sequence data The archive provides a comprehensive record of the world s nucleotide sequencing information covering raw sequencing data sequence assembly information and functional annotation This webinar will introduce you to the data and metadata structures for nucleotides at the ENA It will support you in learning about how you can submit data to this archive and retrieve submitted data relevant to your field of work...

Virtual

21 September 2023

A guided tour of improvements to the UniProt website

Edit

September 21, 2023 15:302023WebinarVirtual

Description This webinar will provide an interactive introduction to the UniProt website Developed with our user community in mind the website aims to allow users to access all data provided by the UniProt consortium while being adaptable enough to meet the evolving needs of our users Join us to find out how our website is structured to enable users to better navigate and find content in our various databases Also discover how to use our tools BLAST Align Peptide search and ID mapping and how to organise them in the Tools results dashboard where the user can view and revisit their previous BLAST Align Peptide search or ID mapping jobs save them as favourites or resubmit them We hope that this interactive webinar will introduce you to all the features and show you some of the latest improvements we implemented into the new website...

Virtual

20 September 2023

Using RNAcentral to explore and investigate non-coding RNA sequences

Edit

September 20, 2023 15:302023WebinarVirtual

Description Non coding RNAs ncRNAs are a key molecule for life They are involved in many complex biological processes from gene regulation to translation This complexity has led to an explosion of many different databases with specialised focuses and data RNAcentral provides users a single entry point into the complexity of ncRNA data This webinar will show users how to effectively navigate and search RNAcentral Additionally we will show users how to download data for their own analysis and tooling We will highlight commonly used data formats such as BED GFF3 and FASTA files Finally we will demonstrate how to use the RNAcentral sequence search to quickly explore sequences...

Virtual

20 September - 23 September 2023

The human microbiome

Edit

September 20, 2023 00:002023ConferenceEMBL Heidelberg, Virtual

Description OverviewSpeakersProgrammePractical informationSponsorsMedia kitPre conference workshop Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Symposium overview Human microbiota the collection of microbes living in and on our body have a significant impact on human health and well being They have been associated with numerous diseases yet we are still far from understanding their role in the context of lifestyle and genetics Various initiatives are underway around the world to survey the human microbiota at several body sites characterise them understand their interactions with the human hosts elucidate their role in diseases and design possible therapeutic or dietary interventions There is a new wave of studies mining the human microbiota for health relevant bioactive compounds for characterising specific microbial strains and for cataloguing the human microbiota from all across the globe This conference will provide plentiful opportunities for researchers to learn about and to connect to important developments in studying the human microbiota The return of this established meeting will bring together the community for a timely in person symposium picking up on developments across the field since the last edition in 2018 For 2023 sessions will focus on the human microbiome across biological time and in nutrition and drugs host microbe interactions integrative approaches in microbiome research and methodological advances in microbiome analysis The final session will look to the future of microbiome research and translation Session topics Methodological advances in microbiome analysis The human microbiome across biological age The human microbiome in nutrition and drugs Host microbe interactions Integrative approaches in microbiome research Future outlook for microbiome research and translation What past participants say about the conference This meeting was in my top 3 of best meetings ever that I attended The atmosphere was very lively with lots of good discussions with diverse scientists The topic microbiome research was covered extremely well I am looking forward to attending the next time this meeting is taking place Peter van Baarlen Wageningen University the Netherlands Please see EMBL s COVID 19 safety recommendations if attending the on site event Speakers Speakers Yasmine Belkaid remote speaker National Institute of Allergy and Infectious Diseases NIH USA Clara Belzer Wageningen University The Netherlands Maria Carmen Collado Spanish National Research Council Spain Mahesh Desai Luxembourg Institute of Health Luxembourg Kenya Honda Keio University School of Medicine Japan Curtis Huttenhower Harvard University USA Rob Knight University of California San Diego USA Sarah Lebeer University of Antwerp Belgium Ruth Ley Max Planck Institute for Biology Germany Lisa Maier University of T bingen Germany Eric Martens University of Michigan USA Julia Salzman Stanford University USA Eran Segal Weizmann Institute of Science Israel Harry Sokol Saint Antoine Hospital France Gene Tyson Queensland University of Technology Australia Paul Wilmes University of Luxembourg Luxembourg Moran Yassour The Hebrew University of Jerusalem Israel Alexandra Zhernakova University of Groningen The Netherlands Scientific Organisers Manimozhiyan Arumugam University of Copenhagen Denmark Ami Bhatt Stanford University USA Peer Bork EMBL Heidelberg Germany Nicola Segata University of Trento Italy Conference Organiser Lea Hohmann EMBL Heidelberg Germany Aline Schnieder EMBL Heidelberg Germany Programme Got something to say Tweet it EESMicrobiome Programme is preliminary and subject to change For registered participants recorded talks will be accessible on demand for 2 weeks after the end of the event unless indicated otherwise Day 1 Wednesday 20 September 2023 Time Europe Berlin Speaker11 15 13 00Registration and light refreshments11 45 12 45Pre conference workshop Robust and versatile ultra high throughput single microbe genome sequencing by Atrandi Biosciences registration required 13 00 13 30Opening remarks and lightning talks by Scientific OrganisersSession 1 Methodological advances in microbiome analysisSession chair Manimozhiyan Arumugam13 30 14 00A pipeline for developing novel therapeutics from the human microbiomeGene Tyson Queensland University of Technology Australia14 00 14 15Ex vivo cultivation model of the complex human gut microbiota for investigating modulation approaches and spatial interactionsAnnelies Geirnaert ETH Zurich Food Biotechnology SwitzerlandNot available on demand14 15 14 30Detecting Natural Selection in the Human MicrobiotaSur Herrera Paredes Universidad Nacional Aut noma de M xico Mexico14 30 15 00Systems ecology of the human expobiomePaul Wilmes University of Luxembourg Luxembourg15 00 15 30Coffee break and meet the speakers15 30 15 45Identification of eukaryotic symbionts and diet as bycatch in human gut microbiome dataOleksandr Maistrenko Royal Netherlands Institute for Sea Research Netherlands15 45 16 Kinetic modeling and in vitro fermentation reveal how gut microbiota impacts bioactivation and bioavailability of phytoestrogensMaja Stevanoska ETH Zurich SwitzerlandNot available on demand16 00 16 30Ultra fast reference free genomics algorithm discover novel genomic regulation in the microbial worldJulia Salzman Stanford University USA Remote speaker 16 30 17 00The Isala project and the vaginal microbiomeSarah Lebeer University of Antwerp Belgium17 00 18 30Global Grants for Gut Health symposium17 00 17 05 Welcome and Introductory RemarksAmi Bhatt Stanford University USA17 05 17 30 Bile Acid Conjugation as a New Mechanism of Host Microbiome CrosstalkRobert Quinn Michigan State University USA17 30 17 55 Using genomics to decode infant dietary diversity and microbiome maturationLawrence David Duke University USA17 55 18 20 Gut microbiome metabolites and growth in children at risk of malnutritionEvans Mudibo Wageningen University KEMRI Wellcome Trust Research Programme18 20 18 25 Concluding RemarksAmi Bhatt Stanford University USA18 30 20 00Dinner in EMBL Canteen20 00 21 00After dinner drinks and speed networking optional 20 00 20 30 Day 2 Thursday 21 September 2023 Time Europe Berlin SpeakerSession 2 The human microbiome across biological ageSession chair Peer Bork09 30 10 00Maternal infant microbiota Factors shaping microbial transfer assembly and evolutionMaria Carmen Collado Spanish National Research Council CSIC Spain10 00 10 15Longitudinal culturing of the developing human microbiome reveals temporal and spatial differentiation between distal body sitesSara Di Simone Hudson Institute of Medical Research Australia10 15 10 30Tracking the transmission of the gut microbiome a one health perspectiveMireia Valles Colomer Pompeu Fabra University Spain10 30 11 00Coffee break and meet the speakers11 00 11 30Toward the development of defined microbial therapeuticsKenya Honda Keio University School of Medicine JapanNot available on demand11 30 11 45Gut metagenomic profiling of 1 800 African women reveals novel microbial diversity and associations with cardiometabolic healthJakob Wirbel Stanford University USA11 45 12 00Unsaturated long chain fatty acids differentially modulate growth of vaginal Lactobacillus speciesMeilin Zhu MIT USANot available on demand12 00 12 30Longitudinal Variability of Bifidobacterium Species in the Infant Gut is Independent of Maternal Milk HMO CompositionMoran Yassour The Hebrew University of Jerusalem IsraelNot available on demand12 30 14 00LunchSession 3 The human microbiome s response to nutrition and drugsSession chair Ami Bhatt14 00 14 30The consequences of drugging the gut microbiome from the individual microbe to the hostLisa Maier University of T bingen GermanyNot available on demand14 30 14 45Baseline gut microbiome predicts the efficacy of randomized oral antihypertensives in patients with essential hypertensionLianmin Chen Nanjing Medical University China14 45 15 00Emergence of community behaviors in the gut microbiota upon drug treatmentSarela Garcia Santamarina ITQB NOVA Portugal15 00 15 30Coffee break and meet the speakers15 30 16 00Dietary fiber and mucin degrading bacteria in inflammatory bowel diseaseEric Martens University of Michigan USA16 00 16 15Investigating microbial dark matter unveils a consistent gut metagenomic biomarker for response to immune checkpoint blockade across diverse cohortsChan Yeong Kim EMBL Heidelberg Germany16 15 16 30Immunotherapy and microbiome unique set of taxa and genes associated with antibiotics useGiacomo Vitali INRAE France16 30 17 00Gut Microbial Synthetic communities to study how microbial ecologic networks collaboratively ferment glycans from diet and mucinClara Belzer Wageningen University The Netherlands17 00 18 30Poster session 1 odd numbers with beer and snacksPlease see the poster overview here Free evening Day 3 Friday 22 September 2023 Time Europe Berlin SpeakerSession 4 Host microbe interactionsSession chair Nicola Segata09 30 10 00Silent flagellins or how the gut immune system turns a blind eyeRuth Ley Max Planck Institute for Biology Germany10 00 10 15Bacterial DNA inversions and functional plasticity during inflammation and encounter with bacteriophagesShaqed Carasso Technion Israel Institute of Technology Israel10 15 10 30Host Microbiome Interactions between Lesional Skin Microbiome and Genomic Profiles in Psoriasis Susceptibility Loci Predisposes to Psoriasis Vulgaris in Indian PatientsSouvik Mukherjee National Institute of Biomedical Genomics India10 30 11 00Coffee break and meet the speakers11 00 11 30Leveraging diet to engineer the gut microbiomeMahesh Desai Luxembourg Institute of Health LuxembourgNot available on demand11 30 11 45A role for the gut microbiome in determining the rate of progression of amyotrophic lateral sclerosisMaria Emilia Panzetta Duke University USA11 45 12 00Extravesicles secreted by human gut GABA producing Bacteroides sp a possible shuttle mechanism for neuroactive metabolitesBasit Yousuf University of Ottawa Canada12 00 12 30Talk title tbcYasmine Belkaid National Institute of Allergy and Infectious Diseases NIH remote speaker12 30 14 00Lunch and Meet the editorsSession 5 Integrative approaches in microbiome researchSession chair Maria Carmen Collado14 00 14 30Microbiome multi omics and the Human Microbiome Bioactives ResourceCurtis Huttenhower Harvard University USA14 30 14 45Microbial sub species diversity and its interactions with host physiologyLiron Zahavi and Saar Shoer Weizmann Institute of Science Israel14 45 15 00Multi view integration of microbiome data for predicting host diseaseEfrat Muller Tel Aviv University Israel15 00 15 30Coffee break and meet the speakers15 30 16 00Development of gut microbiome and virome during the first year of lifeAlexandra Zhernakova University of Groningen The Netherlands16 00 16 15Gut microbial genetic architecture of human healthYue Zhang and Doaming Wang University Medical Center Groningen The NetherlandsNot available on demand16 15 16 30Exploration of 1000 human gut viromes and matched metagenomes discovers phages with unexpected integration potential and broad host rangeLore Van Espen KU Leuven Belgium16 30 17 00Personalized medicine based on deep human phenotypingEran Segal Weizmann Institute of Science Israel17 00 18 30Poster session 2 even numbers with beer and snacksPlease see the poster overview here 18 30 00 00Conference dinner at Heidelberg Castle with band limited seating first come first served Day 4 Saturday 23 September 2023 Time Europe Berlin SpeakerSession 6 Future outlook for microbiome research and translationSession chair Moran Yassour09 30 10 00High throughput approaches for integrated microbiome and metabolome studiesRob Knight University of California San Diego USA10 00 10 15Unraveling the complex interplay between the human gut microbiome diet and cardiometabolic health from the ZOE PREDICT studiesFrancesco Asnicar University of Trento Italy10 15 10 30Revealing the reservoir and spread of antimicrobial resistance in the human gut microbiota using the controlled human infection modelIrina Chelysheva University of Oxford United Kingdom10 30 11 00Coffee Break and Meet the speakers11 00 11 30Host microbiome tryptophan metabolism in IBDHarry Sokol Saint Antoine Hospital France11 30 11 45Fecal metabolic dysbiosis is associated with 30 day mortality of patients on the medical intensive care unitAlexander de Porto University of Chicago USA11 45 12 00Harnessing gut microbiota for risk assessment and therapeutics of NAFLDYueqiong Ni Leibniz Institute for Natural Product Research and Infection Biology Hans Kn ll Institute HKI Germany Remote speaker 12 00 12 15Key metabolic interactions define microbiota response to nutrient changesRemy Young Hudson Institute of Medical Research Australia12 15 12 30Discovery and development of anaerobic microbial choline metabolism inhibitors that target novel proteins beyond the choline utilization gene clusterAmelia Woo Harvard University USANot available on demand12 30 12 45Closing Remarks and Poster Prize12 45 13 15Packed Lunch and departure13 15Buses to downtown Heidelberg and 1 bus to Frankfurt airport terminal 1 30 EUR tickets may be purchased on site Practical information Registration fees and abstract submission On site registration fees include admission conference materials COVID 19 safety measures meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Virtual registration fees include access to all of the talks livestreamed and on demand and facility to submit questions On site Academia 700On site PhD Student 600On site Industry 900Virtual Academia 200Virtual PhD Student 150Virtual Industry 250 A letter to support your visa application will be issued on request once payment of the registration fee is confirmed We recommend that you book your visa appointment as soon as possible to avoid any delay with your visa application Accredited journalists may be eligible to register for complimentary press registration Registrants may be required to provide accreditation or equivalent proof of press membership after registration Please contact Aline Schnieder for more information Please note that we do not offer complimentary registrations for editors of scientific journals Confirmation and payment Registration will be on a first come first served basis Your place can only be confirmed after payment of the registration fee If you are added to our waiting list please consider taking advantage of our offerings to participate virtually On site participants Types of payments accepted are international bank transfers and credit card payments Virtual participants We are only able to accept card payments In exceptional cases we can accept bank transfers Please contact events embl de for details Abstract submission Only participants registering to attend the on site event are eligible to submit an abstract Abstracts will not be accepted from virtual participants After registration you can submit your abstract via a separate link that will be provided in the email confirmation Alternatively you can access the link on the confirmation page directly after registering The same login credentials are used for both processes Please note Abstract body The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised Title The title should not exceed 20 words Only the first word of the title should start with a capital letter and the rest should be lowercase Authors and affiliations Please fill in the author s details as requested in the online form The compulsory fields are First Name Last Name Organisation Name Affiliation or Company Country and Email Kindly mark only one author in the role of First Author and please don t forget to indicate who will be the Presenter Please enter your co authors correctly via the system by adding accounts together with their organisation institute Do not copy paste them into the body of the abstract text as they will not be indexed in the abstract book Presentation types When submitting your abstract you can apply for an oral or poster presentation A selection process will take place with the results announced 2 3 weeks after the abstract submission deadline For detailed instructions on how to submit a conference abstract follow the instructions provided in this video Please check our FAQs pages for further information on how to submit an abstract Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of both registration fee waivers and travel grants These are available for on site participants at EMBL Conferences and EMBO EMBL Symposia and for on site and virtual participants at EMBO Workshops We are currently working on securing funding for all virtual participants and ask that you please apply for financial assistance for both on site and virtual participation Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course or conference Travel grant The travel grant will cover the cost of travel to an on site event airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from within Europe up to 1000 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from outside Europe up to 500 for any participant travelling to an EMBO Workshop up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Workshop up to 700 for any participant working in Croatia Czech Republic Estonia Greece Hungary Italy Lithuania Luxembourg Poland Slovenia and Turkey travelling to an EMBO Workshop Registration fees are only covered for EMBO Workshops The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Application On site participants You may apply for financial assistance when submitting your abstract In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Virtual participants If you are attending virtually you can apply for financial assistance in the submission portal by the abstract deadline Read the instructions on how to apply for financial assistance Only submissions for financial assistance will be accepted Presentation abstracts cannot be submitted here and will be declined In your application you will be asked to summarise your current work answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Selection The scientific organisers will select the recipients of all financial assistance during the abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details View our list of external funding opportunities and information on attending a conference as an event reporter For further information about financial assistance please refer to the FAQ page Accommodation and shuttles Accommodation is not included in the conference registration fee As further changes in our events are possible due to COVID 19 you should book flights trains and hotels with flexible options and favourable cancellation conditions The hotels below have rooms on hold for participants until 23 August 2023 in some cases at special rates Please email the hotel directly quoting the booking code EES23 08 to confirm the exact price of the room Hotel AnlageHotel ibis HeidelbergPremier Inn Heidelberg CityHotel Bayrischer Hof ISG Hotel Staycity Aparthotel HeidelbergB B HotelLeonardo Hotel Heidelberg City CentreHotel Vier Jahreszeiten HeidelbergExzellenz HotelMeininger HeidelbergHotel Holl nder Hof Hotel Monpti Conference shuttle buses Conference shuttle buses are free of charge for participants and depart from designated bus stops near the hotels to EMBL and back mornings and evenings You can now find the Conference Bus Schedule here The bus stops for this conference are Staycity Aparthotel Speyerer Str 7 Kurf rsten Anlage Opposite Main Train Station Premier Inn Kurf rsten Anlage 23 Leonardo Hotel Heidelberg City Center Bergheimer Str 63 Neckarm nzplatz Heidelberg Tourist Information Peterskirche Bus stop in front of Hotel Monpti ISG Hotel Im Eichwald 19 View Conference shuttle bus stops and hotels in a larger map Please note that not every bus stop will be used for every event Further details Address EMBL Meyerhofstra e 1 69117 Heidelberg Germany For further information on getting to EMBL Heidelberg visit Public Transportation to the Venue For information about accommodation and local transportation please refer to the FAQ page On site information Catering All meals and coffee breaks are included in the registration fee Our catering staff will prepare a wide variety of vegetarian meals meat and fish dishes soups pasta fresh fruit and vegetables as well as a variety of desserts Please wear your badge at all times when serving yourself No food or drinks are allowed in the auditorium Charging lockers There are lockers available next to the stairs leading down into the Auditorium You will find some of those equipped with sockets to charge your smartphone tablet etc Electricity and charging station In most places the electricity is 220 volts AC 50 cycles An adaptor and a plug that fits the German socket may be needed for your appliances laptop i e American Japanese etc A USB charging station for electronic devices is available at the registration desk EMBL merchandise If you are interested in purchasing an EMBL souvenir products presented in the glass display in the registration area please ask at the registration desk for more information Health and safety notes Please read EMBL s COVID 19 safety policy for on site events Do not smoke in any EMBL building Eating and drinking is prohibited in the Auditorium and all laboratories Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required The first aid room is located next to the ATC Registration Desk room 10 205 Dial the Emergency number 222 from any EMBL internal phone only Where is the accident What happened How many injured Emergency number 06221 387 7821 from mobile phones Please report all accidents to the conference officer at the registration desk In case of fire Press the nearest fire alarm button or the Emergency number 222 from any internal phone A loud fire alarm will go off if an evacuation is required On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting points Do not use the lifts Beyond first aid Please remember to bring your own medication if needed to the conference Note that the next pharmacy is a 4 minute drive from the EMBL but for many medications you will be required to see a doctor to get a prescription Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg In any case the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary Internet Wi Fi is available everywhere on the premises using the EMBL Events network and the event specific password which will be provided on site The eduroam network secure world wide roaming access service developed for the international research and education community is also available Lost and found Lost and Found are kept at the registration desk until the end of the conference Luggage There are lockers available on site to store your luggage which require a 2 EURO coin to operate There is another luggage room on level E0 which is free to use but remains unlocked during the conference Nursing room There is a nursing room available in the ATC Rooftop Lounge on level A29 Photography During the conference an EMBL Photographer may be taking photographs If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Printing We can help printing your boarding passes train ticket Please send it to events embl de and collect your print outs at the registration desk Room for prayer yoga and meditation There is a room for prayer mediation and yoga located on level E0 behind the Auditorium Please be respectful of other participants using the room Sightseeing A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing Travel to and from the venue During the event we provide conference shuttle buses to and from EMBL In addition there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time Information on the conference shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page Useful German expression Where is the nearest Covid test centre Wo ist das n chste Covid Testzentrum HelloHalloGoodbyeAuf WiedersehenGood morningGuten MorgenGood afternoonGuten TagGood eveningGuten AbendGood nightGute NachtI m sorryTut mir leidExcuse me Entschuldigen SieHow are you Wie gehts I m fine thanks And you Mir geht es gut danke und dir Ihnen What is your nameWie heisst du Wie heissen Sie My name isIch heisseDo you speak EnglishSprechen Sie Englisch I don t understandIch verstehe nichtPlease speak more slowlyK nnen Sie bitte langsamer sprechenThank youDankesch nWhere is the toilet Wo ist die Toilette Please call me a taxiBitte rufen Sie mir ein TaxiHow do I get to Wie komme ich zum zur A beer two beers pleaseEin Bier zwei Bier bitteA glass of red white wine pleaseEin Glas Rot Weisswein bitteThe menu pleaseDie Speisekarte bitteIs there a local speciality Gibt es eine Spezialit t aus dieser Gegend I m VegetarianIch bin VegetarierIt was deliciousEs war hervorragendThe bill pleaseDie Rechnung bitteI have a headacheIch habe KopfschmerzenI have a sore throatIch habe HalsschmerzenMy stomach hurtsIch habe MagenschmerzenI m allergic toIch bin allergisch gegenI need a doctor who speaks EnglishGibt es einen Arzt der Englisch spricht Where is the nearest COVID 19 test centre Wo ist das n chste COVID 19 Testzentrum Virtual participation What s included Access to all the livestreamed talks Video library of the recorded talks during and after the event Facility to submit questions Please note that only on site participants are able to submit abstracts and participate in the poster sessions Event platform We are using an event platform for this conference More information about the platform will be shared ahead of the conference Guidelines Do not broadcast the conference to unregistered participants You are encouraged to tweet and post about the event Tweet unless the speaker specifically says otherwise but be mindful of unpublished data Please do not capture transmit or redistribute data presented at the meeting Additional information can be found in our Code of Conduct Health and well being It is important to stay healthy and move around especially when you are attending an event virtually We have put together a few coffee break stretches and yoga videos in the conference platform for you to enjoy during the event How to ask questions Please use the Q A function in the event platform If you have any other questions you can go to the Help Desk in the event platform Click on more on the top menu and click Help Desk Time zone The programme is planned based on the Europe Berlin time zone unless otherwise stated Please take your time zone into consideration when planning your attendance Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for participants page COVID 19 related questions COVID 19 information for on site events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Silver sponsor Bronze sponsors Session sponsor Event sponsor BaseClear CosmosID Don Whitley Scientific MP Biomedicals Media partners Disease Models Mechanisms The Company of Biologists Journal EMBO Molecular Medicine an EMBO Press journal FEBS Journal a FEBS Press journal FEBS Letters a FEBS Press journal FEBS Open Bio a FEBS Press journal International Union of Biochemistry and Molecular Biology PLOS Biology a PLOS journal Open Biology a Royal Society journal Bio Essays a Wiley Online Library Advanced Biology a Wiley Online Library Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information on sponsoring possibilities If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PTT slide 16 9 Leaderboard 728 90 Pre conference workshop For on site participants only This industry webinar will be hosted by our sponsor Atrandi Biosciences prior to the EMBO EMBL Symposium The human microbiome on Wednesday 20 September 2023 11 45 12 45 Participation in this workshop is free of charge for registered on site conference attendees The number of available places is limited first come first served All registered conference attendees will receive an email with a registration link ABSTRACT Robust and versatile ultra high throughput single microbe genome sequencing by Linas Pupelis Justyna MazulAtrandi Biosciences Whole genome and targeted sequencing open a window to understanding the function of unculturable microorganisms On one hand metagenomic sequencing is attractive for its straightforward sequencing library preparation from bulk environmental samples but only offers limited resolution into individual species On the other hand single microbe sequencing offers true single clone resolution but can only meaningfully address the high biological diversity expected in environmental samples if performed on thousands of individual cells in parallel To satisfy the need to study such large numbers of single microbes per sample well and droplet based approaches keep evolving in parallel to provide single cell compartmentalization required during sequencing library preparation However these approaches suffer from a fundamental trade off between throughput and versatility Being individually addressable microwells enable multi step processing but are not scalable Droplets offer a throughput of up to a million cells per experiment but only allow a limited number of processing steps to be performed The later limitation is severely felt when it comes to microbial research as harsh conditions typically required for lysis are incompatible with downstream nucleic acid barcoding steps Our Semi Permeable Capsule SPC technology combines the throughput of droplets with the versatility of wells by enabling a virtually unlimited number of processing steps on genetic material from millions of individual microbes in parallel We demonstrate the use of SPCs for barcoding 100 000 individual microbial genomes to obtain single microbe whole genome sequencing data of unprecedented quality...

Manimozhiyan Arumugam, Ami Bhatt, Peer Bork, Nicola Segata

EMBO | EMBL Symposium

EMBL Heidelberg, Virtual

19 September - 22 September 2023

CCPBioSim workshop: structural bioinformatics resources and tools for molecular dynamics simulations

Edit

September 19, 2023 00:002023CourseEMBL-EBI

Description This introductory workshop will provide hands on training on protein and structural bioinformatics resources in the context of molecular dynamics biomolecular modelling and simulations The workshop is sponsored by the Collaborative Computational Project for Biomolecular Simulation CCPBioSim Participants will gain knowledge and skills for searching selecting and assessing publicly available protein biodata for use in downstream methods relating to biomolecular modelling and molecular dynamics simulations The workshop will begin with an introduction to basic concepts in genomics and associated resources then to protein resources their uses and limitations and validation of both experimentally and predicted protein structures Finally the workshop will cover variant effect prediction and offer participants hands on group projects to bring together the previous days training with highly experienced mentors During this time participants will work with simulated datasets to answer small research questions then present findings thereafter Participants will also get the chance to network with one another trainers and workshop organisers...

Jane Reynolds

EMBL-EBI

18 September - 22 September 2023

Single cell RNA-seq analysis using Python

Edit

September 18, 2023 00:002023CourseVirtual

Description This course covers the analysis of single cell RNA sequencing scRNA seq data using Python and command line tools Participants will be guided through droplet based scRNA seq analysis pipelines from raw reads to cell clusters You will explore and interpret single cell RNA seq data using Python as well as the Single Cell Expression Atlas Finally you will put their knowledge into practice through a group challenge on the last day Please note that you will not analyse your own data as part of the course There will however be ample opportunity to discuss your research and ideas with other course participants and trainers Virtual course Participants will learn via a mix of pre recorded lectures live presentations and trainer Q A sessions Practical experience will be developed through group activities and trainer led computational exercises Live sessions will be delivered using Zoom with additional support and asynchronous communication via Slack Pre recorded material may be provided before the course starts that participants will need to watch read or work through to gain the most out of the actual training event In the week before the course there will be a brief induction session Computational practicals will run on EMBL EBI s virtual training infrastructure meaning you will not require access to a powerful computer or install complex software on your own machines Participants will need to be available between the hours of 09 00 17 30 BST each day of the course Trainers will be available to assist answer questions and provide further explanations during these times This course is currently under construction and so details are subject to change Please note that we will operate this course virtually Hybrid options are not currently available We reserve the right to change the format of this course or cancel it due to the ongoing coronavirus pandemic...

Juanita Riveros

Virtual

17 September - 22 September 2023

Genome engineering: CRISPR/Cas from cells to mice

Edit

September 17, 2023 00:002023CourseEMBL Heidelberg

Description OverviewSpeakersProgrammePractical InformationSponsorsMedia kit Overview Course overview This course will provide training in genome editing and cell engineering in mammalian cells and mouse embryos using the highly efficient CRISPR Cas9 system Participants will learn design of CRISPR targets using bioinformatics tools generation of gene knock outs knock ins and target validation using the most current technologies The course will be split into two groups mammalian cells OR mice based on participants expertise Please note that all participants are expected to engage in all sessions Participants should plan for approximately 1 hour extra per day for self paced learning modules Audience This course is aimed at researchers who are familiar with basic molecular and cell biology techniques and who want to learn how to create an engineered mammalian cell line or mouse model using the most recent and advanced CRISPR Cas9 system No previous experience in genome editing is required Modules resources How to create a CRISPR Cas9 experiment using various design tools Transfection optimisation for efficient gene editing Generation of knock out and knock in cell lines and mouse embryos Validation of genome edited cell lines and embryos Learning outcomes After this course you should be able to Design a CRISPR based project using editing tools for your target gene of interest Choose the right format of gene editing tool and delivery strategy for your cell type or embryos Edit screen and validate the engineered models embryo manipulation What past participants say about the course The EMBL course about CRISPR applications for genome engineering was an incredible experience From the quality of the lectures the availability of the invited speakers to respond to all questions and doubts the openness and diversity of participants to the great organization and the impressive facilities and core facility teams working there It all created a perfect atmosphere for learning about this groundbreaking technique and the inspiring work being done with it as well as great networking I highly recommend this course Sofia Morazzo International Clinical Research Center Czech Republic The course covers all you need to organise your CRISPR experiments in great detail The speakers are fantastic and eager to help with your specific questions The organisation is also fantastic where you only have to think on CRISPR and nothing else Sergio G San Miguel Max Planck Institute for Infection Biology Germany Please see EMBL s COVID 19 safety policy for testing and other requirements to attend this on site course Speakers Antony Adamson The University of Manchester UK Michela Ascolani EMBL Rome Italy Alessandro Barenghi EMBL Rome Italy Dana Carroll University of Utah School of Medicine USA Silke Deckert Thermo Fisher Scientific Germany Julian Gr newald Technical University of Munich Germany Manuel Kaulich Universit tsklinikum Frankfurt Germany Frank Montoya EMBL Heidelberg Germany Beate Neumann EMBL Heidelberg Germany Alexandre Paix EMBL Heidelberg Germany Kim Remans EMBL Heidelberg Germany Isabel Rollan EMBL Heidelberg Germany Daniel Schraivogel EMBL Heidelberg Germany Maj Simonsen Jackson EMBL Rome Italy Kieran Van Kessel Thermo Fisher Scientific UK Scientific Organisers Neil Humphreys EMBL Rome Italy Kristof Kersse Thermo Fisher Scientific Germany Birgit Koch Max Planck Institute for Medical Research Germany Elisabeth Zielonka EMBL Heidelberg Germany Course Organisers Chris Stocks Course and Conference Team Lead EMBL Heidelberg Germany Swetlana Krez Training Lab EMBL Heidelberg Germany Programme Got something to say Tweet it EMBLCRISPRcas Some pre course work such as watching pre recordings protocol reading and computational exercises with estimated time 0 10 hours will be required and will be shared in advance of the course Some speakers may need to join virtually to give their lecture or Q A and the programme is subject to change Day 1 Sunday 17 September 2023 Time Europe Berlin SessionLocation 16 00 16 30 Registration ISG Hotel16 30 17 30Arrival WelcomeIntroduction to course design ISG Seminar room 17 30 18 00IcebreakerISG Seminar room 18 00 19 00Live Keynote Lecture Introduction to CRISPR Cas 9Dana Carroll University of Utah School of Medicine USA this talk will be remote ISG Seminar room 19 00Dinner Networking ISG Hotel Day 2 Monday 18 September 2023 Time Europe Berlin Session Location08 30 08 45 Bus from ISG Hotel to EMBL ISG Hotel08 45 09 00 Overview of the dayCourtyard Room09 00 12 15Day 2 Guide RNA Design09 00 09 15Lab SafetySwetlana Kretz EMBL Heidelberg GermanyCourtyard Room09 15 10 15Practical 1 gRNA Donor design Kristof Kersse Thermo Fisher Scientific GermanyTraining Lab A B10 15 11 15Practical 1 gRNA Donor designBirgit Koch Max Planck Institute for Medical Research GermanyTraining Lab A B11 15 11 45Coffee 11 45 12 30 Practical in groups11 45 12 30Mammalian Cell GroupPractical 1 1 TrueTag Donor Template Synthesis PCRSilke Deckert Thermo Fisher Scientific GermanyKristof Kersse Thermo Fisher Scientific GermanyKieran Van Kessel Thermo Fisher Scientific UKTraining Lab A 11 45 12 30Mouse Embryo GroupGlass transfer pipet prep harvest embryos and short seminar on embryo transfer and demonstration Neil Humphreys EMBL Rome ItalyMichela Ascolani EMBL Rome ItalyMaj Simonsen Jackson EMBL Rome ItalyAlessandro Barenghi EMBL Rome ItalyIsabel Rollan EMBL Heidelberg GermanyFrank Montoya EMBL Heidelberg GermanyTraining Lab B12 30 13 30Lunch 13 30 14 30Lecture A rationale for efficient genome editing using linear repair donorsAlexandre Paix EMBL Heidelberg GermanyCourtyard Room14 30 16 00Practical 1 2Mammalian Cell Group TrueTag Donor Template Synthesis Gel analysis and Clean upSilke Deckert Thermo Fisher Scientific GermanyKristof Kersse Thermo Fisher Scientific Germany Kieran Van Kessel Thermo Fisher Scientific UKTraining Lab A14 30 16 00Practical 1 2Mouse Embryo Group Intro to TLR2 system describe injection mix prep microinjection zygotes electroporation Electroporation Maj Simonsen Jackson EMBL Rome Italy Michela Ascolani EMBL Rome Italy Alessandro Barenghi EMBL Rome ItalyMicroinjection Neil Humphreys EMBL Rome Italy Isabel Rollan EMBL Heidelberg Germany Frank Diego Montoya Castillo EMBL Heidelberg Germany Sandra Stobrawa Biozol Calibre ScientificTraining Lab B16 00 16 30Coffee 16 30 18 00Practical 2 3Mammalian Cell GroupGroup A gRNA efficiency Lipid transfection of 293FT cells with gRNA and Cas9 protein Lipid transfection of 293FT eBFP cells with gRNA Cas9 protein and ssODNSilke Deckert Thermo Fisher Scientific GermanyKieran Van Kessel Thermo Fisher Scientific UKGroup B Guide RNA design taskBirgit Koch Max Planck Institute for Medical Research GermanyKristof Kersse Thermo Fisher Scientific GermanyCell Culture Flex Lab16 30 18 00Mouse Embryo Group 2nd Microinjection electroporation and AAVElectroporation Maj Simonsen Jackson EMBL Rome Italy Michela Ascolani EMBL Rome Italy Alessandro Barenghi EMBL Rome ItalyMicroinjection Neil Humphreys EMBL Rome Italy Isabel Rollan EMBL Heidelberg Germany Frank Diego Montoya Castillo EMBL Heidelberg Germany Sandra Stobrawa Biozol Calibre ScientificTraining Lab A B18 00 19 00Dinner 19 00 20 30Practical 2 3Mammalian Cell GroupGroup B gRNA efficiency Lipid transfection of 293FT cells with gRNA and Cas9 protein Lipid transfection of 293FT eBFP cells with gRNA Cas9 protein and ssODNSilke Deckert Thermo Fisher Scientific GermanyKieran Van Kessel Thermo Fisher Scientific UK Group A Guide RNA design taskBirgit Koch Max Planck Institute for Medical Research GermanyKristof Kersse Thermo Fisher Scientific GermanyTraining Lab A B19 00 20 30Practical 2 3Mouse Embryo GroupExtra time with Embryos microinjection and embryos transfer KSOM media O N cultureNeil Humphreys EMBL Rome ItalyMichela Ascolani EMBL Rome ItalyMaj Simonsen Jackson EMBL Rome ItalyAlessandro Barenghi EMBL Rome ItalyIsabel Rollan EMBL Heidelberg GermanyFrank Montoya EMBL Heidelberg GermanyTraining Lab A B20 30Bus from EMBL to ISG Hotel Day 3 Tuesday 19 September 2023 Time Europe Berlin SessionLocation08 30 08 45 Bus from ISG Hotel to EMBL08 45 09 15Overview of the day09 15 10 15Lecture Gene editing in different experimental modelsAntony Adamson The University of Manchester UKCourtyard Room10 15 11 15Practical Lecture Mammalian Cell Group Generation and validation of endogenously tagged cell lineBirgit Koch Max Planck Institute for Medical Research Germany Courtyard Room10 15 11 15Practical 4 Mouse Embryo Group Assess and clean up 2 cell microinjected embryosNeil Humphreys EMBL Rome ItalyMichela Ascolani EMBL Rome ItalyIsabel Rollan EMBL Heidelberg Germany Frank Montoya EMBL Heidelberg GermanyTraining Lab A B11 15 11 45Coffee11 45 12 45Lecture CRISPR Prime EditingJulian Gr newald Technical University of Munich GermanyCourtyard Room12 45 13 45Lunch 13 45 15 45Practical 1 3 4Mammalian Cell GroupGroup A Tag Knock in Electroporation of 293FT with gRNA Cas9 protein and TrueTag donor templateSilke Deckert Thermo Fisher Scientific GermanyKieran Van Kessel Thermo Fisher Scientific UK Group B Project discussionBirgit Koch Max Planck Institute for Medical Research GermanyKristof Kersse Thermo Fisher Scientific GermanyCell Culture Flex LabCourtyard Room13 45 15 45Practical 4Mouse Embryo GroupThaw pre prepared blastocysts assess viability and extract DNANeil Humphreys EMBL Rome Italy Michela Ascolani EMBL Rome Italy Maj Simonsen Jackson EMBL Rome Italy Isabel Rollan EMBL Heidelberg Alessandro Barenghi EMBL Rome ItalyTraining Lab A B 15 45 16 15Coffee 16 15 18 15Practical 1 3 4Mammalian Cell GroupGroup B Tag Knock in Electroporation of 293FT with gRNA Cas9 protein and TrueTag donor templateSilke Deckert Thermo Fisher Scientific GermanyKieran Van Kessel Thermo Fisher Scientific UK Group A Project discussionBirgit Koch Max Planck Institute for Medical Research GermanyKristof Kersse Thermo Fisher Scientific GermanyCell Culture Flex Lab16 15 18 15Practical 5Mouse Embryo GroupSet up T7 assay and mutant specific PCRsNeil Humphreys EMBL Rome Italy Michela Ascolani EMBL Rome Italy Maj Simonsen Jackson EMBL Rome Italy Alessandro Barenghi EMBL Rome Italy Training Lab A B18 15 19 15DinnerCanteen19 45Bus from EMBL to ISG hotelEMBL Bus stop Day 4 Wednesday 20 September 2023 Time Europe Berlin SessionLocation08 30 08 45 Bus from ISG Hotel to EMBL 08 45 09 15Overview of the dayCourtyard Room09 15 10 15Lecture Daniel SchraivogelEMBL Heidelberg GermanyCourtyard Room10 15 12 15Practical in GroupsMammalian Cell Group Practicals 5 1 5 2 GCD Cell Harvest and lysis set up GCD PCRSilke Deckert Thermo Fisher Scientific GermanyKristof Kersse Thermo Fisher Scientific GermanyKieran Van Kessel Thermo Fisher Scientific UKTraining Lab B 10 15 12 15Mouse Embryo Group Practicals 5 1 5 22Assess and clean up 4 to 8 cell embryos Run Gels for PCRsSet up T7 assay and digestion assay PCRs Neil Humphreys EMBL Rome Italy Michela Ascolani EMBL Rome Italy Maj Simonsen Jackson EMBL Rome ItalyAlessandro Barenghi EMBL Rome Italy Isabel Rollan EMBL Heidelberg GermanyTraining Lab A 12 30 13 15Lunch 13 15 13 30Group photo13 30 14 30Lecture The 3Cs technology for CRISPR gRNA library generationManuel Kaulich Goethe University GermanyCourtyard Room14 30 16 30Practical in GroupsPractical 5 3 Mammalian Cell GroupCR analysis set up GCD re annealing reactionPractical 5 4 5 5Set up digestion for GCD gel purification sample submission for sanger sequencingGel analysis of GCDSilke Deckert Thermo Fisher Scientific GermanyKristof Kersse Thermo Fisher Scientific GermanyKieran Van Kessel Thermo Fisher Scientific UKFlex Lab A B 14 30 16 30Mouse Embryo Group Project discussion focus on the analysis of sequencing data and design optionsNeil Humphreys EMBL Rome Italy Michela Ascolani EMBL Rome Italy Alessandro Barenghi EMBL Rome Italy Isabel Rollan EMBL Heidelberg Germany Antony Adamson The University of Manchester UKTraining Lab A B16 30 17 00Coffee 17 00 18 00Lecture Imaged based high throughput screening RNAi vs CRISPRBeate Neumann EMBL Heidelberg Germany Courtyard Room18 00 20 30Pizza Dinner and Discussion round and drinks Ethical issues of CRISPR technology and genome engineeringRoof Top Lounge20 30 Bus from EMBL to ISG hotel EMBL bus stop Day 5 Thursday 21 September 2023 Time Europe Berlin SessionLocation08 30 08 45 Bus from ISG Hotel to EMBL 08 45 09 15Overview of the day 09 15 10 45Practical in GroupsMammalian Cell GroupGroup A Examine BFP cells via microscopy and FACSKristof Kersse Thermo Fisher Scientific GermanyKieran Van Kessel Thermo Fisher Scientific UK FACS Specialist Thermo FisherGroup B Knock In cell validation DNA PreparationBirgit Koch Max Planck Institute for Medical Research Germany Training Lab B09 15 10 45Mouse Embryo GroupThaw TLR2 embryos and examine KO and KI morular blastocysts for florescenceKnock In validation Neil Humphreys EMBL Rome Italy Michela Ascolani EMBL Rome Italy Maj Simonsen Jackson EMBL Rome Italy Isabel Rollan EMBL Heidelberg Germany Beate Neumann EMBL Heidelberg GermanyTraining Lab B10 45 11 15Coffee 11 15 12 45Practical in GroupsMammalian Cell GroupKnock In cell validation FACS AnalysisBirgit Koch Max Planck Institute for Medical Research GermanyCell Culture 116 Training Lab B11 15 12 45Mouse Embryo GroupImage embryosNeil Humphreys EMBL Rome ItalyMichela Ascolani EMBL Rome ItalyALMF Facility12 45 13 45Lunch 13 45 15 00Practical in groupsMammalian cell groupKnock In cell validation Set up Junction PCRBirgit Koch Max Planck Institute for Medical Research GermanyNeil Humphreys EMBL Rome ItalyMichela Ascolani EMBL Rome ItalyTraining Lab B 13 45 15 00 Mouse embryo groupTour of LAR Facility 15 00 15 30Break 15 30 16 30Lecture CRISPR Cas genome editing to generate transgenic miceNeil Humphreys EMBL Rome ItalyCourtyard Room16 30 18 30Technology Lounge Genome modification technologiesPresentation by different companies 18 45Bus from EMBL to downtown via ISG Hotel ATC entrance19 00Downtown course dinnerOskars Downtown Day 6 Friday 22 September 2023 Time Europe Berlin SessionLocation08 30 08 45 Bus from ISG Hotel to EMBL ISG Hotel08 45 09 15Overview of the dayCourtyard Room09 15 10 15Lecture Purification of Cas9 proteinKim Remans EMBL Heidelberg GermanyCourtyard Room10 15 11 15Practical in GroupsMammalian Cell GroupGel electrophoresis of junction PCRBirgit Koch Max Planck Institute for Medical Research GermanyTraining Lab B10 15 11 15Mouse Embryo GroupProject discussionNeil Humphreys EMBL Rome ItalyMichela Ascolani EMBL Rome ItalyMaj Simonsen Jackson EMBL Rome ItalyAlessandro Barenghi EMBL Rome ItalyIsabel Rollan EMBL Heidelberg GermanyFrank Montoya EMBL Heidelberg GermanyFlex Lab A B11 15 11 45Break11 45 12 45Practical in GroupsMammalian Cell GroupAnalysis of gel electrophoresisBirgit Koch Max Planck Institute for Medical Research GermanyTraining Lab B11 45 12 45Mouse Embryo GroupProject discussionNeil Humphreys EMBL Rome ItalyMichela Ascolani EMBL Rome ItalyMaj Simonsen Jackson EMBL Rome ItalyAlessandro Barenghi EMBL Rome ItalyIsabel Rollan EMBL Heidelberg GermanyFrank Montoya EMBL Heidelberg GermanyFlex Lab A B12 45 13 45Lunch13 45 15 00The Solution Room Last chance to ask questions Flex Lab A B 15 00 15 30Final discussions feedback session Flex Lab A B Practical Information Registration fees and motivation letter The course is limited to 20 participants For selection purposes please note that your application will not be considered without a letter of motivation Registration Registration fees include admission course materials COVID 19 safety measures meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Academia 790PhD Student 790Industry 1200 NO visa support letters will be issued until payment of the registration fee is confirmed Confirmation and payment The registration fee should be paid only after acceptance to the course The results will be announced approximately 2 3 weeks after the application deadline Motivation letter submission After you have logged in and successfully registered you will receive an email asking you to submit your motivation letter Click on the link provided and enter your motivation letter in the text box provided Alternatively you can submit your motivation letter by clicking on the link on the confirmation page directly after registering Instructions Include your relevant skills experience and qualifications showing why you would be suitable for the course Explain why you would like to attend including what you can contribute and how you think you will benefit from the course Please note The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised For detailed instructions please watch our video on how to submit a course motivation letter Further details For further information about registration and motivation letter submission please refer to the FAQ page Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of both registration fee waivers and travel grants Availability is limited to participants attending on site events in Heidelberg and will be indicated during the abstract or motivation letter submission process Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course or conference Travel grant The travel grant will cover the cost of travel airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Course EMBL Conference or EMBO EMBL Symposium from within Europe up to 1000 for participants travelling to an EMBL Course EMBL Conference or EMBO EMBL Symposium from outside Europe up to 500 for any participant travelling to an EMBO Practical Course or EMBO Workshop up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Practical Course or EMBO Workshop Registration fees are only covered for EMBO Practical Courses or EMBO WorkshopsThe organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant EMBO practical courses and workshops only For EMBO Practical Course or EMBO Workshop participants with children there is the possibility to apply for a childcare grant to offset child care costs incurred by participants or speakers when participating at a course or conference Eligible costs include fees for a babysitter or child care facility travel costs for a caregiver or travel costs for taking the child to the meeting etc Please note that priority will be given to early stage researchers A maximum amount of 500 EUR can be awarded per participant applying for an EMBO Childcare Grant In order to apply for this grant for EMBO Workshops you must be registered by the abstract submission deadline Boehringer ingelheim fonds travel grant Applies to selected courses only Availability will be indicated during the abstract or motivation letter submission process This grant covers costs related to your attendance at the course registration travel and accommodation costs The grant is restricted to PhD students and postdocs who conduct basic biomedical research Whether you are eligible to apply for a travel grant depends on when you received your university entrance qualification e g Abitur A Levels High School Diploma Final State Examination for PhD and MD students as well as graduates the university entrance qualification must not have been obtained more than 11 years ago at the time of the envisaged course for postdocs the university entrance qualification must not have been obtained more than 13 years ago at the time of the envisaged course Application You may apply for financial assistance when submitting your motivation letter for courses and abstract for conferences In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application For the Boehringer Ingelheim Fonds Travel Grant there is a pre application question during the motivation letter submission process and if selected you will be requested to complete a standard form and documentation consisting of your travel expense estimation Selection The scientific organisers will select the recipients of all financial assistance during the motivation letter or abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection is based on your current work or study location the reasons for needing financial support and the impact this event will have on your career Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details See our list of external funding opportunities and information on attending a conference as an event reporter For further information about financial assistance please refer to the FAQ page Accommodation and travel Travel information For travel information please see here If you are travelling to the conference within Germany then you are eligible for the Deutsche Bahn Event Ticket called the Veranstaltungsticket in German This will result in a lower ticket price if your travel distance to Heidelberg is more than 100 km You need to provide proof of your event attendance when purchasing the ticket For more information in English see here or in German see here You can book your ticket here Hotel Single rooms have been reserved for 5 nights 17 21 September 2023 at the ISG Hotel After the selection process selected participants should contact the hotel directly to make a booking booking code GEE23 01 We recommend that all course participants stay at the ISG Hotel which is the dedicated hotel for the course Local transport Shuttle buses will go from the ISG Hotel to EMBL and back mornings and evenings A bus schedule and location of the bus stops will be made available prior to the meeting Further details Address EMBL Heidelberg Meyerhofstra e 1 69117 Heidelberg Germany For more information about accommodation and travel please refer to the FAQ page Event software Event software The EMBL eCampus learning platform will be used to collaborate communicate and network with all of the course participants All participants will receive information on how to join shortly before the course We recommend using Chrome Safari or Mozilla Firefox browsers for eCampus Sponsors Event Partner Event Sponsor Event Supporter Media partners Medinformatics a Gold Open Access journal Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other events or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1080 Social 1600 900 PPT Slide 16 9...

Neil Humphreys, Kristof Kersse, Birgit Koch, Elisabeth Zielonka

EMBL Course

EMBL Heidelberg

13 September 2023

Edit

July 18, 2023 00:002023CourseVirtual

Description Work with Ensembl to master the Ensembl REST API and flexibly access genome wide data such as genes variants regulatory features homologues and alignments...

Louisse Paola Mirabueno

Virtual

16 July - 21 July 2023

Drosophila genetics and genomics

Edit

July 16, 2023 00:002023CourseEMBL Heidelberg, Virtual

Description OverviewSpeakersOnsite programmeVirtual programmePractical informationSponsorsMedia kit Overview Please see EMBL s COVID 19 safety policy for testing and other requirements to attend this on site course Course overview The fruit fly Drosophila has played a leading role in the discovery and dissection of basic biological processes uncovering general principles of development evolution and disease Almost a century of research has generated a powerful genetic toolbox that provides a unique arsenal of methods that can tackle almost any biological question This combined with exciting new technologies developed in recent years have changed the way Drosophila research is conducted enabling biologists to address questions that were impossible to study before The course has three main objectives First to educate and inspire the next generation of scientists by providing an up to date overview and hands on training of contemporary and classic topics spanning state of the art techniques in genetics imaging and genomics Participants will obtain an essential knowledge base combined with practical training forming a launch pad for their research Second to stimulate the exchange of ideas between established and early career scientists enabling participants to better direct their research trajectory Third to provide networking opportunities hence fostering collaborations and career development The new course combines 50 interactive theoretical discussions that have been successfully used to train generations of Drosophila researchers for nearly 30 years combined with 50 new practical hands on cutting edge experiments taught by experts in the field Audience The course is aimed at PhD students and early stage post doctoral researchers who want to start using or enhance their knowledge of Drosophila as a model organism Modules Drosophila anatomy development genetics and outreach advocacy CRISPR design in flies Live imaging in the fly Genomics at single cell resolution Drosophila behavioural analysis Analysis of fly infection Drosophila diversity and evolution Learning outcomes Training session will familiarize attendees with classical and modern approaches to fruit fly genetics and genomics including EMS screens and CRISPR gene editing modern imaging methods behavioural analysis immunity assays and handling wild caught species Speakers Speakers trainers and staff Baptiste Alberti Institute of Functional Genomics of Lyon France Saudat Alishayeva The Friedrich Miescher Laboratory Germany Matthew Benton EMBL Heidelberg Germany Noa Borst EMBL Heidelberg Germany Justin Crocker EMBL Heidelberg Germany Marc Freeman Vollum Institute USA Eileen Furlong EMBL Heidelberg Germany Lautaro Gandara EMBL Heidelberg Germany Hernan Garcia University of California Berkeley USA Yad Ghavi Helm Institute of Functional Genomics of Lyon France Nicolas Gompel Ludwig Maximilians Universit t M nchen Germany Scott Gratz Brown University USA Amanda Larracuente University of Rochester USA Xueying Li EMBL Heidelberg Germany Audrey Medeiros Brown University USA Migla Miskinyte Instituto Gulbenkian de Ci ncia Portugal Kate O Connor Giles Brown University USA Luisa Pallares The Friedrich Miescher Laboratory Germany Mindy Perkins EMBL Heidelberg Germany Ella Preger Ben Noon Technion Israel Institute of Technology Israel Andreas Prokop The University of Manchester UK Julie Simpson University of California Santa Barbara USA James Tan Sheng Yi The Friedrich Miescher Laboratory Germany Lu s Teixeira Cat lica Biomedical Research Centre and Instituto Gulbenkian de Ci ncia Portugal Natascha Turetzek Ludwig Maximilians Universit t M nchen Germany Harald V hringer EMBL Heidelberg Germany Robert Patrick Zinzen Max Delbr ck Center Germany Scientific organisers Justin Crocker EMBL Heidelberg Germany Kate O Connor Giles Brown University USA Ella Preger Ben Noon Technion Israel Institute of Technology Israel Andreas Prokop The University of Manchester UK Course organisers Catherine Casas Course and Conference Officer EMBL Heidelberg Germany Irena Provaznikova Training Laboratory Officer EMBL Heidelberg Germany Onsite programme Got something to say Tweet it EMBODrosophila Some pre course work such as watching pre recordings protocol reading and computational exercises with estimated time 0 10 hours will be required and will be shared in advance of the course Some speakers may need to join virtually to give their lecture or Q A and the programme is subject to change Day 1 Sunday 16 July 2023 Time Europe Berlin SessionLocation14 30 15 00Bus from hotel to EMBL ATC entranceB B Hotel15 00 15 30Registration and light refreshmentsCourtyard Room A B15 30 15 40Welcome introduction and housenotesJustin Crocker EMBL Heidelberg GermanyKate O Connor Giles Brown University USAElla Preger Ben Noon Technion Israel Institute of Technology IsraelAndreas Prokop The University of Manchester UKCourtyard Room A B15 40 15 45Overview of the day The power of Drosophila as a model organismCourtyard Room A B15 45 16 45Ice breaking activity Flash talksCourtyard Room A B16 45 17 05Coffee breakCourtyard Room A B17 05 17 50Lecture Drosophila functional evolutionary genomicsAmanda Larracuente University of Rochester USACourtyard Room A B17 50 18 05Q ACourtyard Room A B18 05 19 35Practical session Drosophila anatomy development genetics and outreach advocacyMatthew Benton EMBL Heidelberg GermanyLautaro Gandara EMBL Heidelberg GermanyAndreas Prokop The University of Manchester UKCourtyard Room A B19 35 21 35Dinner and networkingEMBL Canteen21 35Bus to hotelEMBL Bus Stop Day 2 Monday 17 July 2023 Time Europe Berlin SessionLocation08 30 09 00Bus from hotel to EMBL ATC entranceB B Hotel09 00 09 10Overview of the day Discerning function through perturbationCourtyard Room A B09 10 09 30Lab safety instructionsIrena Provaznikova EMBL Heidelberg GermanyCourtyard Room A B09 30 10 15Lecture Screen design in fliesMarc Freeman Vollum Institute USACourtyard Room A B10 15 10 30Q ACourtyard Room A B10 30 11 00Coffee break and meet the speakersCourtyard Room A B11 00 11 45Lecture Fly behavioural screensJulie Simpson University of California Santa Barbara USACourtyard Room A B11 45 12 00Q ACourtyard Room A B12 00 13 00Lunch breakEMBL Canteen13 00 14 45Practical session CRISPR design in fliesTrainers Noa Borts EMBL Heidelberg GermanyKate O Connor Giles Brown University USAScott Graz Brown University USAAudrey Medeiros Brown University USAComputer Training Lab14 45 15 15Coffee break and meet the speakersfor virtual participantsFlex Lab A B15 15 17 00Practical session CRISPR design in flies continued Trainers Noa Borts EMBL Heidelberg GermanyKate O Connor Giles Brown University USAScott Graz Brown University USAAudrey Medeiros Brown University USAComputer Training Lab17 00 19 30Poster session I 10 students Helix A19 30 20 30Vegetarian dinnerEMBL Canteen20 30Bus to hotelEMBL Bus Stop Day 3 Tuesday 18 July 2023 Time Europe Berlin SessionLocation08 30 09 00Bus from hotel to EMBL ATC entranceB B Hotel09 00 09 10Overview of the day Revealing new insights through live imagingCourtyard Room A B09 10 09 55Lecture Imaging across scalesJustin Crocker EMBL Heidelberg GermanyCourtyard Room A B09 55 10 10Q ACourtyard Room A B10 10 10 40Coffee break and meet the speakersCourtyard Room A B10 40 11 25Lecture Quantitative imaging of transcriptionHernan Garcia University of Berkeley USACourtyard Room A B11 25 11 40Q ACourtyard Room A B11 40 12 40Lecture Intro to live imagingJustin Crocker EMBL Heidelberg GermanyHernan Garcia University of Berkeley USACourtyard Room A B12 40 13 40Lunch BreakEMBL Canteen13 40 14 10Embryo mounting for imagingTraining Lab A B14 10 15 40Practical session Imaging in the flyTrainers Matthew Benton EMBL Heidelberg GermanyNoa Borst EMBL Heidelberg GermanyJustin Crocker EMBL Heidelberg GermanyHernan Garcia University of Berkeley USAMindy Perkins EMBL Heidelberg GermanyTraining Lab A B15 40 16 10Coffee break and meet the speakersfor virtual participantsTraining Lab A B16 10 17 40Practical session Imaging in the fly continued Trainers Matthew Benton EMBL Heidelberg GermanyNoa Borst EMBL Heidelberg GermanyJustin Crocker EMBL Heidelberg GermanyHernan Garcia University of Berkeley USAMindy Perkins EMBL Heidelberg GermanyTraining Lab A B17 40 20 10Poster session II 10 students Helix A20 10 21 10Pizza dinnerATC Rooftop Lounge21 10 22 10Career chatATC Rooftop Lounge22 10Bus to HotelEMBL Bus Stop Day 4 Wednesday 19 July 2023 Time Europe Berlin SessionLocation08 15 09 00Bus from hotel to EMBL ATC entranceB B Hotel09 00 09 10Overview of the dayNew views from single cell genomicsCourtyard Room A B09 10 09 55Lecture Systems biology of neural tissue differentiationRobert Zinzen Max Delbr ck Center for Molecular Medicine GermanyCourtyard Room A B09 55 10 10Q ACourtyard Room A B10 10 10 40Coffee break and meet the speakersCourtyard Room A B10 40 11 25Lecture Three dimensional organization of the genomeYad Ghavi Helm Institute Genomics Functional De Lyon FranceCourtyard Room A B11 25 11 40Q ACourtyard Room A B11 40 12 25Lecture Genome regulation during developmental transitionsEileen Furlong EMBL Heidelberg GermanyCourtyard Room A B12 25 12 40Q ACourtyard Room A B12 40 13 30Lunch BreakEMBL Canteen13 30 13 40Group photoATC Entrance13 40 15 10Practical session Genomics at single cell resolutionTrainers Baptiste Alberti Institute Genomics Functional De Lyon FranceYad Ghavi Helm Institute Genomics Functional De Lyon FranceRobert Zinzen Max Delbr ck Center for Molecular Medicine GermanyTraining Lab A B15 10 15 40Coffee break and meet the speakersfor virtual participantsComputer Training Lab15 40 17 10Practical session Genomics at single cell resolution continued Trainers Baptiste Alberti Institute Genomics Functional De Lyon FranceYad Ghavi Helm Institute Genomics Functional De Lyon FranceHarald V hringer EMBL Heidelberg GermanyRobert Zinzen Max Delbr ck Center for Molecular Medicine GermanyComputer Training Lab17 10 19 10Poster session III 6 virtual students Courtyard Room A B19 10 20 10DinnerEMBL Canteen20 10Bus to hotelEMBL Bus Stop Day 5 Thursday 20 July 2023 Time Europe Berlin SessionLocation08 15 09 00Bus from hotel to EMBL ATC entranceB B Hotel09 00 09 10Overview of the dayDrosophila diversity and evolutionCourtyard Room A B09 10 09 40Lecture The genetic basis of complex traitsLuisa Pallares The Friedrich Miescher Laboratory GermanyCourtyard Room A B09 40 09 55Q ACourtyard Room A B09 55 10 25Coffee break and meet the speakersCourtyard Room A B10 25 10 55Lecture Genetics of phenotype evolutionNicolas Gompel Ludwig Maximilians Universit t M nchen GermanyCourtyard Room A B10 55 11 10Q ACourtyard Room A B11 10 11 55Lecture The evolution of a complex morphology at a single cell resolutionElla Preger Ben Noon Technion Israel Institute of Technology IsraelCourtyard Room A B11 55 12 10Q ACourtyard Room A B12 10 13 10Lunch BreakEMBL Canteen13 10 15 10Practical session Drosophila behavioral analysisTrainers Saudat Alishayeva The Friedrich Miescher Laboratory GermanyNicolas Gompel Ludwig Maximilians Universit t M nchen GermanyLuisa Pallares The Friedrich Miescher Laboratory GermanyJames Tan Sheng Yi The Friedrich Miescher Laboratory GermanyNatascha Turetzek Ludwig Maximilians Universit t M nchen GermanyTraining Lab A B15 10 15 40Coffee break and meet the speakersfor virtual participantsCourtyard Room A B15 40 17 40Practical session Drosophila behavioral analysis continued Trainers Saudat Alishayeva The Friedrich Miescher Laboratory GermanyNicolas Gompel Ludwig Maximilians Universit t M nchen GermanyLuisa Pallares The Friedrich Miescher Laboratory GermanyJames Tan Sheng Yi The Friedrich Miescher Laboratory GermanyNatascha Turetzek Ludwig Maximilians Universit t M nchen GermanyTraining Lab A B17 40 18 25Bus to city centre with 10 min stop at hotel EMBL Bus Stop18 25 19 30Free afternoon City Centre19 30 21 30Downtown dinnerUrban Kitchen Day 6 Friday 21 July 2023 Time Europe Berlin SessionLocation08 15 09 00Bus from hotel to EMBL ATC entranceB B Hotel09 00 09 10Overview of the dayOrganismal interactionsCourtyard Room A B09 10 09 55Lecture The interaction of Drosophilamelanogaster with microorganismsLu s Teixeira Cat lica Biomedical Research Centre and Instituto Gulbenkian de Ci ncia PortugalCourtyard Room A B09 55 10 10Q ACourtyard Room A B10 10 10 40Coffee break and meet the speakersCourtyard Room A B10 40 12 10Practical session Analysis of fly infectionTrainer Matthew Benton EMBL Heidelberg GermanyLautaro Gandara EMBL Heidelberg GermanyMigla Miskinyte Instituto Gulbenkian de Ci ncia PortugalLu s Teixeira Cat lica Biomedical Research Centre and Instituto Gulbenkian de Ci ncia PortugalTraining Lab A B12 10 13 10Lunch BreakEMBL Canteen13 10 14 10Wrap up of practicals and final data analysisCourtyard Room A B14 10 15 10Feedback round and departureCourtyard Room A B Virtual programme Got something to say Tweet it EMBODrosophila All lectures panels and discussions will be live streamed facilitating enhanced informal discussions Pre course work such as watching pre recordings protocol reading and computational exercises with estimated time 0 10 hours will be required and will be shared in advance of the course Virtual participants will have access to the practical sessions in the form of virtual learning activities in the EMBL eCampus platform and live Q A with the trainers Some practical sessions may be delivered in a fully hybrid mode Some speakers may need to join virtually to give their lecture or Q A and the programme is subject to change The course will be live streamed in CET time zone and lectures will not be recorded Day 1 Sunday 16 July 2023 Time Europe Berlin Session15 30 15 40Welcome introduction and housenotesJustin Crocker EMBL Heidelberg GermanyKate O Connor Giles Brown University USAElla Preger Ben Noon Technion Israel Institute of Technology IsraelAndreas Prokop The University of Manchester UK15 40 15 45Overview of the day The power of Drosophila as a model organism15 45 16 45Ice breaking activity Flash talks16 45 17 05Break17 05 17 50Lecture Drosophila functional evolutionary genomicsAmanda Larracuente University of Rochester USA17 50 18 05Q A18 05 19 35Practical session Drosophila anatomy development genetics and outreach advocacyMatthew Benton EMBL Heidelberg GermanyLautaro Gandara EMBL Heidelberg GermanyAndreas Prokop The University of Manchester UK Day 2 Monday 17 July 2023 Time Europe Berlin Session09 00 09 10Overview of the day Discerning function through perturbation09 10 09 30Lab safety instructionsIrena Provaznikova EMBL Heidelberg Germany09 30 10 15Lecture Screen design in fliesMarc Freeman Vollum Institute USA10 15 10 30Q A10 30 11 00Break11 00 11 45Lecture Fly behavioural screensJulie Simpson University of California Santa Barbara USA11 45 12 00Q A12 00 13 00Break13 00 14 45Practical session CRISPR design in fliesTrainers Noa Borts EMBL Heidelberg GermanyKate O Connor Giles Brown University USAScott Graz Brown University USAAudrey Medeiros Brown University USA14 45 15 15Meet the speakers for virtual participants15 15 17 00Practical session CRISPR design in flies continued Trainers Noa Borts EMBL Heidelberg GermanyKate O Connor Giles Brown University USAScott Graz Brown University USAAudrey Medeiros Brown University USA Day 3 Tuesday 18 July 2023 Time Europe Berlin Session09 00 09 10Overview of the dayRevealing new insights through live imaging09 10 09 55Lecture Imaging across scalesJustin Crocker EMBL Heidelberg Germany09 55 10 10Q A10 10 10 40Break10 40 11 25Lecture Quantitative imaging of transcriptionHernan Garcia University of Berkeley USA11 25 11 40Q A11 40 12 40Lecture Intro to live imaging Justin Crocker EMBL Heidelberg GermanyHernan Garcia University of Berkeley USA12 40 13 40Break13 40 14 10Embryo mounting for imaging14 10 15 40Practical session Imaging in the flyTrainers Matthew Benton EMBL Heidelberg GermanyNoa Borst EMBL Heidelberg GermanyJustin Crocker EMBL Heidelberg GermanyHernan Garcia University of Berkeley USAMindy Perkins EMBL Heidelberg Germany15 40 16 10Meet the speakers for virtual participants16 10 17 40Practical session Imaging in the fly continued Trainers Matthew Benton EMBL Heidelberg GermanyNoa Borst EMBL Heidelberg GermanyJustin Crocker EMBL Heidelberg GermanyHernan Garcia University of Berkeley USAMindy Perkins EMBL Heidelberg Germany Day 4 Wednesday 19 July 2023 Time Europe Berlin Session09 00 09 10Overview of the day New views from single cell genomics09 10 09 55Lecture Systems Biology of Neural Tissue DifferentiationRobert Zinzen Max Delbr ck Center for Molecular Medicine Germany09 55 10 10Q A10 10 10 40Break10 40 11 25Lecture Three dimensional organization of the genomeYad Ghavi Helm Institute Genomics Functional De Lyon France11 25 11 40Q A11 40 12 25Lecture Genome regulation during developmental transitionsEileen Furlong EMBL Heidelberg Germany12 25 12 40Q A12 40 15 10Break15 10 15 40Meet the speakers for virtual participants15 40 17 10Practical session Genomics at single cell resolutionTrainers Baptiste Alberti Institute Genomics Functional De Lyon FranceYad Ghavi Helm Institute Genomics Functional De Lyon FranceHarald V hringer EMBL Heidelberg GermanyRobert Zinzen Max Delbr ck Center for Molecular Medicine Germany17 10 19 10Poster session III 6 virtual students Day 5 Thursday July 2023 Time Europe Berlin Session09 00 09 10Overview of the dayDrosophila diversity and evolution09 10 09 40Lecture The genetic basis of complex traitsLuisa Pallares The Friedrich Miescher Laboratory Germany09 40 09 55Q A09 55 10 25Break10 25 10 55Lecture Genetics of phenotype evolutionNicolas Gompel Ludwig Maximilians Universit t M nchen Germany10 55 11 10Q A11 10 11 55Lecture The evolution of a complex morphology at a single cell resolutionElla Preger Ben Noon Technion Israel Institute of Technology Israel11 55 12 10Q A12 10 13 10Break13 10 15 10Practical session Q A Genomics at single cell resolution15 10 15 40Meet the speakers for virtual participants Day 6 Friday 21 July 2023 Time Europe Berlin Session09 00 09 10Overview of the day Organismal interactions09 10 09 55Lecture The interaction of Drosophila melanogaster with microorganismsLu s Teixeira Cat lica Biomedical Research Centre and Instituto Gulbenkian de Ci ncia Portugal09 55 10 10Q A10 10 10 40Break10 40 12 10Practical session Q A Drosophila behavioral analysis12 10 13 10Break13 10 14 10Wrap up of practicals and final data analysis14 10 15 10Feedback round Practical information Registration fees and motivation letter The course is limited to 20 onsite and 5 virtual participants For selection purposes please note that your application will not be considered without a letter of motivation Registration On site registration fees include admission course materials COVID 19 safety measures meals and coffee breaks This EMBO course includes accommodation and transportation to and from the ISG Hotel to the venue Virtual registration fees include access to live streamed course content lectures Q A sessions with speakers and trainers discussion rounds as well as virtual learning activities in the learning platform On site Academia 500On site PhD Student 500On site Industry 1000Virtual Academia 190Virtual PhD Student 190Virtual Industry 250 A letter to support your visa application will be issued on request once payment of the registration fee is confirmed We recommend that you book your visa appointment as soon as possible to avoid any delay with your visa application Confirmation and payment The registration fee should be paid only after acceptance to the course The results will be announced approximately 2 3 weeks after the application deadline Motivation letter submission After you have logged in and successfully registered you will receive an email asking you to submit your motivation letter Click on the link provided and enter your motivation letter in the text box provided Alternatively you can submit your motivation letter by clicking on the link on the confirmation page directly after registering Instructions Include your relevant skills experience and qualifications showing why you would be suitable for the course Explain why you would like to attend including what you can contribute and how you think you will benefit from the course Please note The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised For detailed instructions please watch our video on how to submit a course motivation letter Further details For further information about registration and motivation letter submission please refer to the FAQ page Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of both registration fee waivers and travel grants Availability is limited to participants attending on site EMBL Courses and virtual or on site EMBO Practical Courses in Heidelberg and will be indicated during the motivation letter submission process Your place in the course is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course Travel grant The travel grant will cover the cost of travel airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Course within Europe up to 1000 for participants travelling to an EMBL Course from outside Europe up to 500 for any participant travelling to an EMBO Practical Course up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Practical Course up to 700 for any participant working in Croatia Czech Republic Estonia Greece Hungary Italy Lithuania Luxembourg Poland Slovenia and Turkey travelling to an EMBO Practical Course Registration fees are only covered for EMBO Practical Courses The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant EMBO Practical Courses only For EMBO Practical Course participants with children there is the possibility to apply for a childcare grant to offset child care costs incurred by participants or speakers when participating at a course Eligible costs include fees for a babysitter or child care facility travel costs for a caregiver or travel costs for taking the child to the meeting etc Please note that priority will be given to early stage researchers A maximum amount of 500 can be awarded per participant applying for an EMBO childcare grant Boehringer Ingelheim Fonds travel grant Applies to selected courses only Availability will be indicated during the motivation letter submission process This grant covers costs related to your attendance at the course registration travel and accommodation costs The grant is restricted to PhD students and postdocs who conduct basic biomedical research Whether you are eligible to apply for a travel grant depends on when you received your university entrance qualification e g Abitur A Levels High School Diploma Final State Examination for PhD and MD students as well as graduates the university entrance qualification must not have been obtained more than 11 years ago at the time of the envisaged course for postdocs the university entrance qualification must not have been obtained more than 13 years ago at the time of the envisaged course Application You may apply for financial assistance when submitting your motivation letter for courses In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application For the Boehringer Ingelheim Fonds Travel Grant there is a pre application question during the motivation letter submission process and if selected you will be requested to complete a standard form and documentation consisting of your travel expense estimation Selection The scientific organisers will select the recipients of all financial assistance during the motivation letter selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the course Selection is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details See our list of external funding opportunities and for further information about financial assistance please refer to the FAQ page Accommodation and shuttles Hotel Accommodation has been pre booked for you at the B B Hotel for the default dates of 16 to 21 July 5 nights Please note that the onsite course registration fee includes coverage of accommodation costs in twin rooms including breakfasts for your stay at the B B Hotel In case you would like to have a single room please let us know and please note that you will be required to pay an additional cost of 31 50 per night This should be paid by you directly to the Hotel during your stay Any additional nights need to be booked and paid for by you We recommend that all course participants stay at the B B Hotel which is the dedicated hotel for the course Local transport Shuttle buses will go from the B B Hotel to EMBL and back mornings and evenings A bus schedule and location of the bus stops will be made available prior to the meeting Further details Address EMBL Heidelberg Meyerhofstra e 1 69117 Heidelberg GermanyFor further information on getting to EMBL Heidelberg visit our Travel Information page For enquiries about accommodation and local transportation please refer to the FAQ page Event software Event software The EMBL eCampus learning platform will be used to collaborate communicate and network with all of the course participants All participants will receive information on how to join shortly before the course We recommend using Chrome Safari or Mozilla Firefox browsers for eCampus Technical Requirements Virtual participants Below you will find the software and technical requirements for this course You will need admin rights to be able to install the software on your computer and we recommend you try this before the course If you do not have admin rights please contact your technical support team in advance to make sure the software can be installed Internet requirements Client computer with fast and stable internet access for the live virtual sessions Minimum 50 mbit download and 10 mbit upload suitable for pre recorded lectures Preferred 100 mbit download and upload at your host institute While using the software during the course please make sure you have nothing else using your bandwidth We recommend using a wired connection Other Information A classroom application like Zoom will be used for the live talks and Q A sessions More information will be provided closer to the start of the course Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page COVID 19 related questions COVID 19 information for on site events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Event partner Event sponsor Event supporter Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other events or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 PPT Slide 16 9...

Justin Crocker, Kate O'Connor-Giles, Ella Preger-Ben Noon, Andreas Prokop

EMBO Practical Course

EMBL Heidelberg, Virtual

11 July - 14 July 2023

Predicting evolution

Edit

July 11, 2023 00:002023ConferenceEMBL Heidelberg, Virtual

Description OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Conference overview Advances in genome sequencing and gene editing tools are providing unprecedented insights into biological mechanisms and evolutionary processes In parallel computational and theoretical approaches are providing new insights into our understanding of these new data A goal for this conference is to unite people across theoretical and experimental backgrounds into a coherent focus on predicting evolution The conference will explore the evolution of biological systems at different levels from genes and molecules to organism development and ecology As such we have invited leaders in their respective fields across various scales of evolution molecular network microbial developmental and community Particular emphasis for this conference will be placed on understanding evolution through mechanistic biology We will explore recent advances in experimental and theoretical approaches to study how genetic and non genetic changes drive and constrain evolution The meeting will offer a training ground and productive learning experience for attendees and provide networking opportunities for scientists across disciplines relevant to evolutionary biology It should be of particular interest to those working at the interface of evolution quantitative genetics development and systems biology Session topics Predicting the evolution of molecules part 1 Predicting regulatory network evolution Predicting cellular evolution Prediction developmental evolution Predicting population and community evolution Predicting the evolution of molecules part 2 Please see EMBL s COVID 19 safety recommendations if attending the on site event Speakers Naama Barkai Weizmann Institute of Science Israel Camille Berthelot Institut Pasteur France Virginie Courtier Orgogozo Institut Jacques Monod Paris France Justin Crocker EMBL Heidelberg Germany Carl de Boer University of British Columbia Vancouver Canada Gautam Dey EMBL Heidelberg Germany Maitreya Dunham University of Washington Seattle USA Georg Hochberg Max Planck Institute for Terrestrial Microbiology Germany Hopi E Hoekstra Harvard University HHMI Cambridge USA Amanda Larracuente University of Rochester USA Michael L ssig University of Cologne Germany Mia Levine University of Pennsylvania USA Peter Lind Ume University Sweden Zachary Lippman CSHL HHMI New York USA Duncan Odom German Cancer Research Center Germany Brandon Ogbunu Yale University New Haven USA Joshua Payne ETH Zurich Switzerland Catherine Peichel University of Bern Switzerland Tzachi Pilpel Weizmann Institute of Science Israel Patricia Wittkopp University of Michigan USA Pedro Beltrao ETH Zurich Switzerland Christian Landry Institute of Integrative and Systems Biology Canada Scientific organisers Justin Crocker EMBL Heidelberg Germany Gautam Dey EMBL Heidelberg Germany Joshua Payne ETH Zurich Switzerland Patricia Wittkopp University of Michigan USA Conference organiser Inna B sselmann EMBL Heidelberg Germany Programme Got something to say Tweet it EMBOPredictEvo Programme is preliminary and subject to change For registered participants recorded talks will be accessible on demand for 2 weeks after the end of the event All times in the programme below are shown as the time in Europe Berlin Day 1 Tuesday 11 July 2023 Time Europe Berlin Speaker11 30 13 00Registration and light refreshments13 00 13 15Opening remarksSession 1 Predicting the evolution of molecules part 1Chairs Patricia Wittkopp Frank Albert13 15 13 40Meiotic drive and satellite DNA in DrosophilaAmanda Larracuente University of Rochester USA 13 40 14 05Epistasis between promoter activity and coding mutations shapes gene evolvabilityChristian Landry Institute of Integrative and Systems Biology CanadaNot available on demand14 05 14 30Towards a mechanistic basis of evolvabilityTzachi Pilpel Weizmann Institute of Science Israel14 30 14 45Evolutionary playgrounds and how to find them Alexandra Dallaire Royal Botanic Gardens Kew UK14 45 15 00Mutational hotspots of T G in bacteria can be constructed by manipulating local nucleotide context James Horton University of Bath UK15 00 15 30Coffee Break and meet the speakers15 30 15 55Clustering structures at the scale of the known protein universe to study protein evolutionPedro Beltrao ETH Zurich Switzerland15 55 16 10Epistasis facilitates functional evolution in an ancient transcription factor Brian Metzger Purdue University USA16 10 16 25B subtilis underground metabolic richness hinders evolutionary predictability Lianet Noda Garc a The Hebrew University of Jerusalem Israel16 25 16 50The evolution of transcription factor binding specificity a role for disordered regionsNaama Barkai Weizmann Institute of Science Israel16 50 17 15 Antagonistic coevolution preserves genome integrityMia Levine University of Pennsylvania USANot available on demand17 15 17 30Flash talks 117 30 19 00Dinner in canteen19 00 21 00Pub quiz after dinner drinks in canteen Day 2 Wednesday 12 July 2023 Time Europe Berlin SpeakerSession 2 Predicting regulatory network evolutionChairs Joshua Payne Tamar Friedlander09 15 09 40 Evolutionary changes in gene regulatory networks inferred from patterns of co expressionPatricia Wittkopp University of Michigan USA09 40 09 55Predictive genotype phenotype fitness mapping of tetracycline resistance Mato Lagator University of Manchester UK09 55 10 10The contribution of alternative splicing to adaptation in threespine stickleback Carlos Ramirez University of Bern Switzerland10 10 10 35Predicting the evolution of Sars CoV 2Michael L ssig University of Cologne Germany10 35 11 05Coffee break and meet the speakers11 05 11 30Predicting cis regulatory evolution using a deep learning oracleCarl de Boer University of British Columbia Canada11 30 11 45Towards interpretable genomic predictions effect propagation in gene regulatory networks Natalia Ruzickova Institute of Science and Technology Austria11 45 12 00Origin and evolution of dynamic properties of gene regulatory circuits in fluctuating environments Mariana G mez Schiavon Universidad Nacional Aut noma de M xico Mexico12 00 12 25Does lab yeast evolution predict wild yeast evolution Maitreya Dunham University of Washington Seattle USA12 25 14 00LunchSession 3 Predicting cellular evolution Chairs Gautam Dey Tim Fuqua14 00 14 25A foray into convergent mechanisms of embryo implantationCamille Berthelot Institut Pasteur France14 25 14 40Genetic variation in the ubiquitin proteasome system Frank Albert University of Minnesota USA14 40 14 55The Evolution of Biomolecular Condensates Why is it an exciting and fundamental problem Pouria Dasmeh University of Marburg Germany14 55 15 10Simple rules govern metabolome evolution in animals Balazs Papp Biological Research Centre Szeged Hungary 15 10 15 40Coffee break and meet the speakers15 40 15 55Acquired antimicrobial resistance affects the evolvability of resistance to further antibiotic exposure Maria Rosa Domingo Sananes Nottingham Trent University UK15 55 16 10Bacterial evolved resistance against host targeting drugs culminates in predictable antibiotic cross resistance Amir Mitchell University of Massachusetts Medical School USANot available on demand16 10 16 35Predicting experimental evolution in PseudomonasPeter Lind Ume University SwedenNot available on demand16 35 17 00A tail of tales convergent phenotypes driven by divergent genotypesHopi E Hoekstra Harvard University HHMI Cambridge USA remote talk 17 00 17 15Flash talks 217 15 19 00Poster session 1 odd numbers 19 00Free evening Day 3 Thursday 13 July 2023 Time Europe Berlin SpeakerSession 4 Prediction developmental evolutionPatricia Wittkopp Virginie Courtier Orgogozo09 15 09 40 Multidimensional Approach to Decoding the Mysteries of Animal DevelopmentJustin Crocker EMBL Heidelberg Germany09 40 09 55Studying enhancer evolution in Drosophila trichome development using neural networks Tatiana Gaitan Stowers Institute for Medical Research USA 09 55 10 10Polyploidization can we predict its evolutionary pathway David Peris CSIC University of Oslo Spain10 10 10 35Genetic and nongenetic evolutionary determinants of cancer driver choiceDuncan Odom German Cancer Research Center Germany10 35 11 05Coffee break and meet the speakers11 05 11 30Replaying the tape of life how predictable is evolutionCatherine Peichel University of Bern Switzerland11 30 11 45Exploring the mechanisms of adaptation to altered glucose homeostasis in blind Mexican cavefish Ansa Cobham Stowers Institute for Medical Research USA11 45 12 00Evolution of the capability for regulation of gene expression in the symbionts of reed beetles Ana Carvalho Max Planck Institute for Chemical Ecology Germany12 00 12 25Diversification of duplicated genes and their cis regulatory control in shaping natural and engineered plant phenotypesZachary Lippman CSHL HHMI New York USANot available on demand12 25 14 00LunchSession 5 Prediction population and community evolutionJustin Crocker Joe Thornton14 00 14 25The predictability of protein evolution under rewired genetic codesJoshua Payne ETH Zurich SwitzerlandNot available on demand14 25 14 40Strong environmental memory revealed by experimental evolution in static and fluctuating environmentsClare Abreu Stanford University USA14 40 14 55Evolutionary adaptations in microbial microcosms are largely independent of the presence of coevolving species Jonathan Friedman Hebrew University of Jerusalem Israel14 55 15 10Developmental selection and its impact on evolutionary trajectories Paco Majic ETH Zurich Switzerland15 10 15 40Coffee break and meet the speakers15 40 15 55Evolving insertion sequences into promotersTimothy Fuqua University of Zurich Switzerland15 55 16 10The role of promiscuous molecular recognition in the evolution of RNase based self incompatibility Tamar Friedlander Hebrew University of Jerusalem IsraelNot available on demand16 10 16 25The rise Patterns of recombination in snakes reveal a tug of war between PRDM9 and promoter like featuresCarla Hoge Columbia University New York USA16 25 16 40Broad Explorations of SARS CoV 2 Omicron Lineage Protein LandscapesThomas Dupic Harvard University USA16 40 16 55Flash talks 316 55 19 00Poster session 2 even numbers 19 00 21 00Conference dinner in the canteen21 00 23 00Conference party Day 4 Friday 14 July 2023 Time Europe Berlin SpeakerSession 6 Predicting the evolution of molecules part 2Chairs Joshua Payne and Balazs Papp 09 15 09 40The evolutionary road to complexity of earth s most important CO2 fixing enzymeGeorg Hochberg MPI Marburg Germany09 40 09 55A rugged yet easily navigable fitness landscape of antibiotic resistance Andrei Papkou University of Zurich Switzerland09 55 10 10The global simplicity of protein sequence function relationships Joe Thornton University of Chicago USA10 10 10 35Provisional parcels for predicting evolutionBrandon Ogbunu Yale University New Haven USA remote talk 10 35 11 05Coffee break and meet the speakers11 05 11 30Predicting the mutations underlying phenotypic evolution using GephebaseVirginie Courtier Orgogozo Institut Jacques Monod Paris France11 30 11 45How does temperature adaptation influence the evolvability of proteins David Schnettler ETH Zurich Switzerland11 45 12 00Genomic analysis predicts the emergence of de novo Oxalate Metabolism in E coli during Lab Evolution Avihu Yona The Hebrew University Jerusalem Israel12 00 12 15Closing remarks and poster prizeJustin Crocker12 15 13 00Packed lunch and departure13 00Optional Bus to Frankfurt airport Terminal 1 Practical information Registration fees and abstract submission On site registration fees include admission conference materials COVID 19 safety measures meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Virtual registration fees include access to all of the talks livestreamed and on demand and facility to submit questions On site Academia 450On site PhD Student 350On site Industry 750Virtual Academia 200Virtual PhD Student 150Virtual Industry 250 NO visa support letters will be issued until payment of the registration fee is confirmed Accredited journalists may be eligible to register for a reduced press rate or in some cases for complimentary registration Registrants may be required to provide accreditation or equivalent proof of press membership after registration Please contact Inna B sselmann for more information Please note that we do not offer complimentary registrations for editors of scientific journals Confirmation and payment Registration will be on a first come first served basis Your place can only be confirmed after payment of the registration fee If you are added to our waiting list please consider taking advantage of our offerings to participate virtually On site participants Types of payments accepted are international bank transfers and credit card payments Virtual participants We are only able to accept card payments In exceptional cases we can accept bank transfers Please contact events embl de for details Abstract submission Only participants registering to attend the on site event are eligible to submit an abstract Abstracts will not be accepted from virtual participants After registration you can submit your abstract via a separate link that will be provided in the email confirmation Alternatively you can access the link on the confirmation page directly after registering The same login credentials are used for both processes Please note Abstract body The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised Title The title should not exceed 20 words Only the first word of the title should start with a capital letter and the rest should be lowercase Authors and affiliations Please fill in the author s details as requested in the online form The compulsory fields are First Name Last Name Organisation Name Affiliation or Company Country and Email Kindly mark only one author in the role of First Author and please don t forget to indicate who will be the Presenter Please enter your co authors correctly via the system by adding accounts together with their organisation institute Do not copy paste them into the body of the abstract text as they will not be indexed in the abstract book Presentation types When submitting your abstract you can apply for an oral or poster presentation A selection process will take place with the results announced 2 3 weeks after the abstract submission deadline For detailed instructions on how to submit a conference abstract follow the instructions provided in this video Please check our FAQs pages for further information on how to submit an abstract Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of both registration fee waivers and travel grants These are available for on site participants at EMBL Conferences and EMBO EMBL Symposia and for on site and virtual participants at EMBO Workshops We are currently working on securing funding for all virtual participants and ask that you please apply for financial assistance for both on site and virtual participation Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course or conference Travel grant The travel grant will cover the cost of travel to an on site event airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from within Europe up to 1000 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from outside Europe up to 500 for any participant travelling to an EMBO Workshop up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Workshop up to 700 for any participant working in Croatia Czech Republic Estonia Greece Hungary Italy Lithuania Luxembourg Poland Slovenia and Turkey travelling to an EMBO Workshop Registration fees are only covered for EMBO Workshops The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant EMBO Workshops only For EMBO Workshop participants with children there is the possibility to apply for a childcare grant to offset child care costs incurred by participants or speakers when participating at a conference Eligible costs include fees for a baby sitter or child care facility travel costs for a caregiver or travel costs for taking the child to the meeting etc Please note that priority will be given to early stage researchers A maximum amount of 500 can be awarded per participant applying for an EMBO childcare grant In order to apply for this grant for EMBO Workshops you must be registered by the abstract submission deadline Application On site participants You may apply for financial assistance when submitting your abstract In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Virtual participants If you are attending virtually you can apply for financial assistance in the submission portal by the abstract deadline Read the instructions on how to apply for financial assistance Only submissions for financial assistance will be accepted Presentation abstracts cannot be submitted here and will be declined In your application you will be asked to summarise your current work answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Selection The scientific organisers will select the recipients of all financial assistance during the abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details View our list of external funding opportunities and information on attending a conference as an event reporter For further information about financial assistance please refer to the FAQ page Accommodation and shuttles Accommodation is not included in the conference registration fee As further changes in our events are possible due to COVID 19 you should book flights trains and hotels with flexible options and favourable cancellation conditions The hotels below have rooms on hold for participants until 13 June 2023 in some cases at special rates Please email the hotel directly quoting the booking code PEV23 01 to confirm the exact price of the room Hotel AnlageHotel Holl nder Hof Hotel MonptiHotel Bayrischer Hof Hotel ibis HeidelbergPremier Inn Heidelberg CityB B HotelISG Hotel Staycity Aparthotel HeidelbergExzellenz Hotel Leonardo Hotel Heidelberg City CentreSteffi s Hostel Heidelberg Conference shuttle buses Conference shuttle buses are free of charge for participants and depart from designated bus stops near the hotels to EMBL and back mornings and evenings You can find the final bus schedule here The bus stops for this conference are Kurf rsten Anlage Opposite Main Train Station Hotel Premier Kurf rsten Anlage 23 Leonardo Hotel Bergheimer Str Neckarmuenzplatz Peterskirche ISG Hotel View Conference shuttle bus stops and hotels in a larger map Please note that not every bus stop will be used for every event You can find the final bus schedule here Further details Address EMBL Meyerhofstra e 1 69117 Heidelberg Germany For further information on getting to EMBL Heidelberg visit Public Transportation to the Venue For information about accommodation and local transportation please refer to the FAQ page On site information Catering All meals and coffee breaks are included in the registration fee Our catering staff will prepare a wide variety of vegetarian meals meat and fish dishes soups pasta fresh fruit and vegetables as well as a variety of desserts Please wear your badge at all times when serving yourself No food or drinks are allowed in the auditorium Charging lockers There are lockers available next to the stairs leading down into the Auditorium You will find some of those equipped with sockets to charge your smartphone tablet etc Electricity and charging station In most places the electricity is 220 volts AC 50 cycles An adaptor and a plug that fits the German socket may be needed for your appliances laptop i e American Japanese etc A USB charging station for electronic devices is available at the registration desk EMBL merchandise If you are interested in purchasing an EMBL souvenir products presented in the glass display in the registration area please ask at the registration desk for more information Health and safety notes Please read EMBL s COVID 19 safety policy for on site events Do not smoke in any EMBL building Eating and drinking is prohibited in the Auditorium and all laboratories Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required The first aid room is located next to the ATC Registration Desk room 10 205 Dial the Emergency number 222 from any EMBL internal phone only Where is the accident What happened How many injured Emergency number 06221 387 7821 from mobile phones Please report all accidents to the conference officer at the registration desk In case of fire Press the nearest fire alarm button or the Emergency number 222 from any internal phone A loud fire alarm will go off if an evacuation is required On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting points Do not use the lifts Beyond first aid Please remember to bring your own medication if needed to the conference Note that the next pharmacy is a 4 minute drive from the EMBL but for many medications you will be required to see a doctor to get a prescription Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg In any case the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary Internet Wi Fi is available everywhere on the premises using the EMBL Events network and the event specific password which will be provided on site The eduroam network secure world wide roaming access service developed for the international research and education community is also available Lost and found Lost and Found are kept at the registration desk until the end of the conference Luggage There are lockers available on site to store your luggage which require a 2 EURO coin to operate There is another luggage room on level E0 which is free to use but remains unlocked during the conference Nursing room There is a nursing room available in the ATC Rooftop Lounge on level A29 Photography During the conference an EMBL Photographer may be taking photographs If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Printing We can help printing your boarding passes train ticket Please send it to events embl de and collect your print outs at the registration desk Room for prayer yoga and meditation There is a room for prayer mediation and yoga located on level E0 behind the Auditorium Please be respectful of other participants using the room Sightseeing A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing Travel to and from the venue During the event we provide conference shuttle buses to and from EMBL In addition there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time Information on the conference shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page Useful German expressions HelloHalloGoodbyeAuf WiedersehenGood morningGuten MorgenGood afternoonGuten TagGood eveningGuten AbendGood nightGute NachtI m sorryTut mir leidExcuse me Entschuldigen SieHow are you Wie gehts I m fine thanks And you Mir geht es gut danke und dir Ihnen What is your nameWie heisst du Wie heissen Sie My name isIch heisseDo you speak EnglishSprechen Sie Englisch I don t understandIch verstehe nichtPlease speak more slowlyK nnen Sie bitte langsamer sprechenThank youDankesch nWhere is the toilet Wo ist die Toilette Please call me a taxiBitte rufen Sie mir ein TaxiHow do I get to Wie komme ich zum zur A beer two beers pleaseEin Bier zwei Bier bitteA glass of red white wine pleaseEin Glas Rot Weisswein bitteThe menu pleaseDie Speisekarte bitteIs there a local speciality Gibt es eine Spezialit t aus dieser Gegend I m VegetarianIch bin VegetarierIt was deliciousEs war hervorragendThe bill pleaseDie Rechnung bitteI have a headacheIch habe KopfschmerzenI have a sore throatIch habe HalsschmerzenMy stomach hurtsIch habe MagenschmerzenI m allergic toIch bin allergisch gegenI need a doctor who speaks EnglishGibt es einen Arzt der Englisch spricht Virtual Participation What s included Access to all the livestreamed talks Video library of the recorded talks during and after the event Facility to submit questions Please note that only on site participants are able to submit abstracts and participate in the poster sessions Event platform We are using an event platform for this conference More information about the platform will be shared ahead of the conference Guidelines Do not broadcast the conference to unregistered participants You are encouraged to tweet and post about the event Tweet unless the speaker specifically says otherwise but be mindful of unpublished data Please do not capture transmit or redistribute data presented at the meeting Additional information can be found in our Code of Conduct Health and well being It is important to stay healthy and move around especially when you are attending an event virtually We have put together a few coffee break stretches and yoga videos in the conference platform for you to enjoy during the event How to ask questions Please use the Q A function in the event platform If you have any other questions you can go to the Help Desk in the event platform Click on more on the top menu and click Help Desk Time zone The programme is planned based on the Europe Berlin time zone unless otherwise stated Please take your time zone into consideration when planning your attendance Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page COVID 19 related questions COVID 19 information for on site events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Event supporter Media partners International Union of Biochemistry and Molecular Biology Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information on sponsoring possibilities If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9 Leaderboard 728 90...

Justin Crocker, Gautam Dey, Joshua Payne, Patricia Wittkopp

EMBO Workshop

EMBL Heidelberg, Virtual

11 July - 13 July 2023

Open Virtual Ensembl Browser Workshop

Edit

July 11, 2023 00:002023CourseVirtual

Description Work with the Ensembl Outreach team to get to grips with the Ensembl browser accessing gene variation comparative genomics and regulation data and mine these data with BioMart...

Louisse Paola Mirabueno

Virtual

10 July - 14 July 2023

Fluorescence imaging beyond intensity

Edit

July 10, 2023 00:002023CourseEMBL Heidelberg

Description OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview This course is organised in cooperation with Leica Microsystems Course overview As fluorescence lifetime based readouts become more accessible this course aims to provide a broad understanding of how the lifetime based information can be leveraged to solve biological questions This application centred course will provide insights into how this additional dimension of fluorescence information can help unveil functional and mechanistic information Audience This course is aimed at PhD students and Post Docs with experience in fluorescence microscopy It will enable them to better apply confocal fluorescence microscopy and in particular lifetime based readouts to their cutting edge research disseminate their gained expertise to colleagues at their home institution and eventually to develop imaging methods beyond the state of the art Modules resources Measuring protein protein interactions Environmental sensing with FRET based and non FRET based biosensors Using fluorescence lifetime for multiplexing Increasing the resolution with tauSTED Endogenous fluorescence harnessing additional information and removing unwanted fluorescence like autofluorescence and background fluorescence Sessions at the microscopes to practice using lifetime imaging in exemplary workflows Analysis of the lifetime based information and applicative conclusions Learning outcomes Understand the basics of fluorescence lifetime Identify which types of research questions and approaches can benefit from lifetime related measurements and how to design such experiments Learn to use common biosensors probes and fluorophores and understand the additional information and contrast provided by fluorescence lifetime Understand the basis of endogenous fluorescence in particular in tissue and animal models and how fluorescence lifetime can help to exploit or cope with their signals Acquire and analyze lifetime related information in different experimental setups Please see EMBL s COVID 19 safety policy for testing and other requirements to attend this on site course Speakers Speakers trainers and staff Luiz Alvarez Leica Microsystems CMS GmbH Germany Marie Erard Universit Paris Saclay France Dorus Gadella Swammerdam Institute for Life Sciences The Netherlands Mariano Gonzalez Pisfil Biomedical Center Munich LMU Munich Germany Manuel Gunkel EMBL Heidelberg Germany Elizabeth Hinde University of Melbourne Australia Kees Jalink The Netherlands Cancer Institute The Netherlands Zhongxiang Jiang Leica Microsystems CMS GmbH Germany Kai Johnsson Max Planck Institute for Medical Research Germany Birgit Koch Max Planck Institute for Medical Research Germany Marko Lampe EMBL Heidelberg Germany Giulia Ossato Leica Microsystems CMS GmbH Germany Sergi Padilla Parra King s College London UK Julia Roberti Leica Microsystems CMS GmbH Germany Ulf Schwarz Leica Microsystems CMS GmbH Germany Irmtraud Steinmetz Leica Microsystems CMS GmbH Germany Timo Zimmermann EMBL Heidelberg Germany Scientific organisers Luis Alvarez Leica Microsystems CMS GmbH Germany Manuel Gunkel EMBL Heidelberg Germany Birgit Koch Max Planck Institute for Medical Research Germany Andrea M lter Leica Microsystems CMS GmbH Germany Course organisers Chris Stocks Course and Conference Team Lead EMBL Heidelberg Germany Swetlana Krez Training Lab Manager EMBL Heidelberg Germany Programme Got something to say Tweet it EMBLFluorescenceLifetime Some pre course work such as watching pre recordings protocol reading and computational exercises with estimated time 0 10 hours will be required and will be shared in advance of the course Some speakers may need to join virtually to give their lecture or Q A and the programme is subject to change All participants will attend all practicals in turns Day 1 Monday 10 July 2023 Time SpeakerLocation08 40Bus from ISG hotel to EMBLISG hotel bus stop09 00 09 15 Welcome registrationEMBL Imaging Centre09 15 09 45Icebreaking activityEMBL Imaging Centre09 45 10 45 Lecture Introduction to fluorescence lifetime based readoutsKees Jalink Dorus Gadella EMBL Imaging Centre10 45 11 00Coffee BreakEMBL Imaging Centre11 00 12 00Lecture Visualization and analysis of lifetime based informationGiulia Ossato Leica Microsystems CMS GmbH GermanyEMBL Imaging Centre12 00 13 00LunchEMBL Canteen13 00 14 00Lecture The application of FRET FLIM to study protein protein interactions and spatial organization of proteins in the cells Marie Erard Universit Paris Saclay FranceEMBL Imaging Centre14 00 16 00Practical sessions 1 2EMBL Imaging Centre16 00 16 15Coffee breakEMBL Imaging Centre16 15 17 45Practical sessions 1 2EMBL Imaging Centre17 45 18 00Wrap up sessionEMBL Imaging Centre18 00 19 00DinnerEMBL canteen19 45 Bus from EMBL to ISG HotelEMBL bus stop Day 2 Tuesday 11 July 2023 TimeSpeakerLocation08 40Bus from ISG hotel to EMBLISG hotel bus stop09 00 11 00 Participants flash talksEMBL Imaging Centre11 00 11 15Coffee breakEMBL Imaging Centre11 15 12 15 Lecture Time Domain Fluorescence lifetime Imaging of cAMP Levels with EPAC Based FRET SensorsKees Jalink The Netherlands Cancer Institute The NetherlandsEMBL Imaging Centre12 15 13 15 LunchEMBL Canteen13 15 14 00 Lecture Fluorescence lifetime based biosensorsDorus Gadella Swammerdam Institute for Life Sciences The NetherlandsEMBL Imaging Centre14 00 16 00Practical sessions 1 2EMBL Imaging Centre16 00 16 15Coffee breakEMBL Imaging Centre16 15 17 45Practical sessions 1 2EMBL Imaging Centre17 45 18 00Wrap up sessionEMBL Imaging Centre18 00 19 30Tips Tricks with concurrent Pizza dinnerEMBL Imaging Centre19 45Bus from EMBL to ISG HotelEMBL bus stop Day 3 Wednesday 12 July 2023 TimeSpeakerLocation08 40Bus from ISG hotel to EMBLISG hotel bus stop09 00 10 00 Lecture Introduction to STED microscopy and tauSTEDUlf Schwarz Leica Microsystems CMS GmbH GermanyEMBL Imaging Centre10 00 11 00 Lecture STED microscopy with a single depletion laser using five fluorochromes and fluorescence lifetime phasor separationMariano Gonzalez Pisfil Biomedical Center Munich GermanyEMBL Imaging Centre11 00 11 15 Coffee breakEMBL Imaging Centre11 15 12 00 Lecture Label free imaging and endogenous fluorescence Giulia Ossato Leica Microsystems CMS GmbH GermanyEMBL Imaging Centre12 00 12 15Group photoEMBL Imaging Centre12 15 13 15LunchEMBL canteen13 15 15 45 Practical sessions 3 6EMBL Imaging Centre15 45 16 15Coffee breakEMBL Imaging Centre16 15 18 45Practical sessions 3 6EMBL Imaging Centre18 45 19 00Wrap up sessionEMBL Imaging Centre19 00 20 30Dinner discussionsEMBL canteen20 35Bus from EMBL to ISG HotelEMBL bus stop Day 4 Thursday 13 July 2023 TimeSpeakerLocation08 40Bus from ISG hotel to EMBLISG hotel bus stop09 00 10 00 Lecture TauSense Tools making lifetime based readouts easily accessibleJulia Roberti Leica Microsystems CMS GmbH GermanyEMBL Imaging Centre10 00 11 00Lecture Synthetic fluorescent probes for live cell imagingKai Jonsson Max Planck Institute for Medical Research GermanyEMBL Imaging Centre11 00 11 15Coffee breakEMBL Imaging Centre11 15 12 15Lecture FP based Multicolour experiments with FLIMSergi Padilla Parra King s College UKEMBL Imaging Centre12 15 13 15LunchEMBL Imaging Centre13 15 15 45Practical sessions 3 6EMBL Imaging Centre15 45 16 15Coffee breakEMBL Imaging Centre16 15 18 45Practical sessions 3 6EMBL Imaging Centre18 45 19 15Wrap up sessionEMBL Imaging Centre19 45Bus to Heidelberg downtownEMBL bus stop20 00 22 00Course dinner downtown Day 5 Friday 14 July 2023 TimeSpeakerLocation08 40Bus from ISG hotel to EMBLISG hotel bus stop09 00 10 00 Lecture The phasor approach to fluorescence lifetime analysis of biosensor F rster resonance energy transfer FRET Elisabeth Hinde University of Melbourne AustraliaEMBL Imaging Centre10 00 11 00Lecture Open discussionEMBL Imaging Centre11 00 11 15Coffee breakEMBL Imaging Centre11 15 12 15Practical session Lifetime based readout analysis and interpretationEMBL Imaging Centre12 15 13 15Lunch EMBL Imaging Centre13 15 15 15Practical session Lifetime based readout analysis and interpretationEMBL Imaging Centre15 15 15 30Coffee breakEMBL Imaging Centre15 30 16 15Round Table The future of lifetime based read outs16 15 16 30Feedback round and Wrap up16 30Bus to Heidelberg train station and city centerEMBL bus stop Practical information Registration fees and motivation letter The course is limited to 20 participants For selection purposes please note that your application will not be considered without a letter of motivation Registration Registration fees include admission course materials COVID 19 safety measures meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Academia 500PhD Student 500Industry 1000 NO visa support letters will be issued until payment of the registration fee is confirmed Confirmation and payment The registration fee should be paid only after acceptance to the course The results will be announced approximately 2 3 weeks after the application deadline Motivation letter submission After you have logged in and successfully registered you will receive an email asking you to submit your motivation letter Click on the link provided and enter your motivation letter in the text box provided Alternatively you can submit your motivation letter by clicking on the link on the confirmation page directly after registering Instructions Include your relevant skills experience and qualifications showing why you would be suitable for the course Explain why you would like to attend including what you can contribute and how you think you will benefit from the course Please note The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised For detailed instructions please watch our video on how to submit a course motivation letter Further details For further information about registration and motivation letter submission please refer to the FAQ page Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of both registration fee waivers and travel grants Availability is limited to participants attending on site EMBL Courses and virtual or on site EMBO Practical Courses in Heidelberg and will be indicated during the motivation letter submission process Your place in the course is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course Travel grant The travel grant will cover the cost of travel airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Course within Europe up to 1000 for participants travelling to an EMBL Course from outside Europe up to 500 for any participant travelling to an EMBO Practical Course up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Practical Course up to 700 for any participant working in Croatia Czech Republic Estonia Greece Hungary Italy Lithuania Luxembourg Poland Slovenia and Turkey travelling to an EMBO Practical Course Registration fees are only covered for EMBO Practical Courses The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Boehringer Ingelheim Fonds travel grant Applies to selected courses only Availability will be indicated during the motivation letter submission process This grant covers costs related to your attendance at the course registration travel and accommodation costs The grant is restricted to PhD students and postdocs who conduct basic biomedical research Whether you are eligible to apply for a travel grant depends on when you received your university entrance qualification e g Abitur A Levels High School Diploma Final State Examination for PhD and MD students as well as graduates the university entrance qualification must not have been obtained more than 11 years ago at the time of the envisaged course for postdocs the university entrance qualification must not have been obtained more than 13 years ago at the time of the envisaged course Application You may apply for financial assistance when submitting your motivation letter for courses In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application For the Boehringer Ingelheim Fonds Travel Grant there is a pre application question during the motivation letter submission process and if selected you will be requested to complete a standard form and documentation consisting of your travel expense estimation Selection The scientific organisers will select the recipients of all financial assistance during the motivation letter selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the course Selection is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details See our list of external funding opportunities and for further information about financial assistance please refer to the FAQ page Accommodation and shuttles Hotel Single rooms have been reserved for 6 nights Sunday 9 July to Saturday 15 July 2023 at the ISG Hotel After the selection process selected participants should contact the hotel directly to make a booking booking code MIC23 03 We recommend that all course participants stay at the ISG Hotel which is the dedicated hotel for the course Local transport Shuttle buses will go from the ISG Hotel to EMBL and back mornings and evenings A bus schedule and location of the bus stops will be made available prior to the meeting Further details Address EMBL Heidelberg Meyerhofstra e 1 69117 Heidelberg GermanyFor further information on getting to EMBL Heidelberg visit our Travel Information page For enquiries about accommodation and local transportation please refer to the FAQ page Technical requirements and event software Technical requirements Below you will find the software and technical requirements for this course Participants need to bring their own laptops which will be used to remotely access EMBL virtual machines with pre installed software You will need admin rights to install the software required to access the virtual machines If you do not have admin rights please contact your technical support team in advance to make sure the software can be installed If you have a non standard HDMI port other than type A you need to bring an adaptor Keyboard and PC mouse are available for use with a standard USB port If you have a different port type such as USB C you will need to bring your own Event software The EMBL eCampus learning platform will be used to collaborate communicate and network with all of the course participants All participants will receive information on how to join shortly before the course We recommend using Chrome Safari or Mozilla Firefox browsers for eCampus Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page COVID 19 related questions COVID 19 information for on site events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Co organisers Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other events or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9...

Luis Alvarez, Manuel Gunkel, Birgit Koch, Andrea Mülter

EMBL Course

EMBL Heidelberg

10 July - 14 July 2023

Cancer genomics and transcriptomics

Edit

July 10, 2023 00:002023CourseEMBL-EBI

Sophie Spencer

EMBL-EBI

5 July 2023

A guide to sequence analysis resources in Job Dispatcher

Edit

July 05, 2023 15:302023WebinarVirtual

Description The Job Dispatcher team at EMBL EBI provides access to various bioinformatics sequence analysis tools and biological datasets This webinar will introduce different tool categories and explain how to find access and use these tools for your sequence analysis It will cover the latest features and user documentation of the sequence analysis tools and also demonstrate how to access these tools programmatically...

Virtual

3 July - 4 July 2023

Development and morphogenesis: Symposium in honour of Maria Leptin

Edit

July 03, 2023 00:002023ConferenceOther

Description If you are not redirected please visit the event website...

Fiona Watt

Conference

Other

3 July - 7 July 2023

Proteomics bioinformatics

Edit

July 03, 2023 00:002023CourseEMBL-EBI

Description This course provides hands on training in the basics of mass spectrometry MS and proteomics bioinformatics Participants will receive training on how to use search engines and post processing software quantitative approaches MS data repositories the use of public databases for protein analysis annotation of subsequent protein lists and incorporation of information from molecular interaction and pathway databases This course is organised in association with the Vlaams Instituut voor Biotechnologie VIB In person course The course fee is inclusive of four nights of accommodation and catering including dinner We plan to deliver this course in person onsite at our training suite at EMBL EBI Hinxton Please be aware that we are continually evaluating the ongoing pandemic situation and as such may need to change the format of courses at short notice Your safety is paramount to us you can read our COVID guidance policy for more information All information is correct at time of publishing Please also note that there are delays in the issuing of visas from the UK Government We encourage you to check if you need a visa and apply in plenty of time before travelling Current waiting times are more than six weeks For more information please visit the UK Government website...

Shereen Pethania

EMBL-EBI

Edit

June 25, 2023 00:002023CourseEMBL Barcelona

Description The course will combine lectures and hands on exercises to Introduce attendees to key practicalities of working with high performance computing HPC clusters Build first hand experience in using PerMedCoE modelling tools CellNOpt CARNIVAL COBREXA MaBoSS PhysiCell and PhysiBoSS Develop a practical appreciation of using workflow managers and containerised PerMedCoE modelling tools to execute biomedical workflows It will also include poster sessions where participants can present their work and plenty of time for interaction between participants and between participants and trainers This course will take place at the Hotel Montany in Seva less than an hour away from Barcelona Visit the PerMedCoE summer school website for more information...

Juanita Riveros

EMBL Barcelona

21 June 2023

A guide to identifying suitable patient-derived cancer models in CancerModels.Org

Edit

June 21, 2023 15:302023WebinarVirtual

Description Patient derived cancer models PDCMs have become an essential tool in both cancer research and preclinical studies Each model type offers unique advantages and is better suited for specific research areas cell lines are low cost and allow high throughput assays organoids model the impact of intratumour heterogeneity tumour evolution and drug response and patient derived xenografts PDXs retain the tumour architecture to better predict patient response to treatment Seamless access to PDCMs is however hindered by the lack of shared data standards As such PDCMs stakeholders i e researchers clinicians bioinformaticians and analytical tool developers are faced with the challenge to navigate a complex and siloed landscape across multiple commercial and academic resources CancerModels Org is a new cancer research platform that aggregates clinical genomic and functional data from PDXs organoids and cell lines The platform addresses the needs of the stakeholders by standardising harmonising and integrating the complex and diverse data associated with patient derived cancer models Its foundation is underpinned by our efforts to develop and promote the use of descriptive standards e g PDX MI PMID 29092942 to facilitate data interoperability and global sharing of models Further value is provided by enriching the models and data with concepts from well established terminologies e g NCI Thesaurus and links to external resources such as publication platforms raw data archives and cancer specific annotation tools enabling exploration and prioritisation of cancer model variation data CancerModels Org is freely available under an Apache 2 0 license https github com PDCMFinder...

Virtual

19 June - 21 June 2023

Edit

June 15, 2023 15:002023WebinarVirtual

Description Nowadays GPU programming plays an important role in software development The massive parallel hardware enables us to analyze bigger datasets process data in finer details or visualize simulations in real time Still due to the programming complexity and the lack of knowledge GPUs are not regularly used in many scientific fields Thankfully GPU programming matures and provides simpler tools to utilize GPU hardware In this presentation we describe multiple GPU programming frameworks ranging from high level to low level and showcase them on selected bioinformatics algorithms About the speaker Adam melko is a third year doctoral student in the Department of Distributed and Dependable Systems at Charles University in Prague with the dissertation topic of Employing parallel computing in data intensive tasks He specializes in GPU programming and in the analysis of memory accesses in programs His current research topic involves development of tools for effective memory layouts and traversals of data structures...

Adam Smelko

Virtual

12 June - 15 June 2023

Life at the periphery: mechanobiology of the cell surface

Edit

June 12, 2023 00:002023ConferenceEMBL Heidelberg, Virtual

Description OverviewSpeakersProgrammePractical informationSponsorsAboutMedia kit Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Symposium overview After a very engaging virtual first edition in 2021 this hybrid symposium on cell surface mechanics will bring together researchers across kingdoms of life interested in dynamic processes occurring at the cell surface The focus will be on new technologies that empower studies of cell wall cytoskeleton and membrane biology such as advanced imaging in in vitro and in vivo systems as well as approaches combining molecular biology with computational and biophysical approaches The first edition started building a much needed bridge between the wall and wall less fields This edition will cement that bridge but turn the focus to the balance between keeping a particular cell morphology necessary for function while allowing the dynamic processes that must occur at the cell surface The goal is to inspire and induce collaborations across these communities to reach a comprehensive understanding of the biology at the cell surface integrating cell wall actin and membrane biochemistry and biophysics with cell mechanics Topics In vitro reconstitution of the cell surface Cell surface in a single cell Planetary mechanobiology Cell surface mechanics in multicellular systems Modelling the cell surface What past participants say about the symposium Life at the Periphery was a rewarding opportunity to connect with people across the world and see some amazing science I really appreciated in the different sessions how the organizers worked hard to pair seemingly different topics fields of research together it made us see the common threads of interest we have in different domains of biology Michael Henderson Institut Curie Please see EMBL s COVID 19 safety recommendations if attending the on site event Speakers Patricia Bassereau Institut Curie France Buzz Baum MRC Laboratory of Molecular Biology UK Peter Bieling Max Planck Institute of Molecular Physiology Germany Sandra Citi University of Geneva Switzerland Alba Diz Mu oz EMBL Heidelberg Germany Anna Erzberger EMBL Heidelberg Germany Lillian Fritz Laylin University of Massachusetts Amherst USA Anja Geitmann McGill University Canada KC Huang Stanford University USA Chien Jung Lo National Central University Taiwan Satyajit Mayor National Centre for Biological Sciences India Bela Mulder AMOLF Netherlands Dyche Mullins University of California San Francisco USA Alexandre Persat EPFL Switzerland Hawa Racine Thiam Stanford University USA Virtual Pere Roca Cusachs Soulere Institute for Bioengineering of Catalonia IBEC Spain Enrique Rojas New York University USA Katja R per MRC Laboratory of Molecular Biology UK Jakub Sedzinski Novo Nordisk Foundation Center for Stem Cell Medicine reNEW Denmark Carolina Tropini The University of British Columbia Canada Viola Vogel ETH Z rich Switzerland Kirsty Wan University of Exeter UK Scientific organisers Alba Diz Mu oz EMBL Heidelberg Germany Zemer Gitai Princeton University USA KC Huang Stanford University USA Ewa Paluch University of Cambridge UK Conference organiser Maria Mercedes Bacadare Goitia EMBL Heidelberg Germany Programme Got something to say Tweet it EESCellSurface Please note that due to the ongoing pandemic situation some speakers may need to join virtually to give their talk and the programme is subject to change For registered participants recorded talks will be accessible on demand for 2 weeks after the end of the event unless indicated otherwise Day 1 Monday 12 June 2023 Time Europe Berlin Speaker12 30 14 00Registration and light refreshments14 00 14 15Opening remarks14 15 18 30Session 1Chair Alexandre Persat EPFL Switzerland14 15 14 45Cell adhesion and spreading on fluid membranes through microtubules dependent mechanotransductionPatricia Bassereau Institut Curie France14 45 15 15Physical and embodied intelligence at the ciliated surfaceKirsty Wan University of Exeter UK15 15 15 30Plasma membrane shape homeostasis in response to cell stretchAnabel Lise Le Roux Institute for Bioengineering of Catalonia Spain15 30 16 00Chytrid fungi differentiate from cell types with an animal like actin cortex to cells with actin patches and a fungal cell wallLillian Fritz Laylin University of Massachusetts Amherst USA16 00 16 45Coffee Break and Meet the speakers 16 45 17 15Getting stressed versus going with the flow the mechanical and diffusive properties of the bacterial cell envelopeKC Huang Stanford University USA17 15 17 30Hydrogel based Molecular Tension Fluorescence Microscopy for Investigating Integrin mediated Rigidity SensingZheng Liu Wuhan University China17 30 17 45Waves on the surface of rewired oocytes membrane patterning and cytoskeletal biomechanicsAndrew Goryachev University of Edinburgh United Kingdom17 45 18 00Aberrant cortex contractions impact mammalian oocyte qualityElvira Nikalayevich Center for Interdisciplinary Research in Biology Coll ge de France France18 00 18 30From the cell surface to the nucleus through integrins and intermediate filamentsPere Roca Cusachs Soulere Institute for Bioengineering of Catalonia and University of Barcelona Spain18 30 20 00Dinner in Canteen 20 00 21 30Drinks in ATC Roof top lounge Day 2 Tuesday 13 June 2023 Time Europe Berlin Speaker09 00 12 00Session 2Chair Lillian Fritz Laylin University of Massachusetts Amherst USA09 00 09 30Probing bacterial cell wall growth by tracing wall anchored protein complexesChien Jung Lo National Central University Taiwan09 30 09 45Mechanical polarity of the cell cortexAnumita Jawahar PMMH ESPCI Institut Curie France09 45 10 00Membrane to cortex attachment determines different mechanical phenotypes in LGR5 and LGR5 colorectal cancer cellsSefora Conti Institute for Bioengineering of Catalonia Spain10 00 10 30Coffee Break and Meet the speakers 10 30 11 00Multi scale control of structural functionality in plantsAnja Geitmann McGill University Canada11 00 11 15Contribution of cell mechanics in promoting supracellular migrationSelena Gupta New York University United States of America11 15 11 30Hepatocyte apical bulkheads provide a mechanical means to oppose bile pressureMatthew Bovyn Max Planck Institute for Cellular Biology and Genetics Germany11 30 12 00A molecular view on the control of actin turnover by phosphate releasePeter Bieling Max Planck Institute of Molecular Physiology Germany12 00 12 25Flash talks 2 minutes 1 slide per talk 49 Sebastian Aland 51 Raul Aparicio Yuste 53Natalia Baranova 55 Catherine Villard 57 Andrea Disanza 59 Jaime Fernandez Sobaberas 61 Carolin Gierse 63 Xiangfu Guo 65 Saurabh Kaushik and 69 Jesus Lopz Gay Orts12 25 13 25Lunch13 25 14 25Panel Discussion ChatGPT or Family and science discussion14 25 17 25Session 3Chair Carolina Tropini The University of British Columbia Canada14 25 14 55Sub surface activities the role of the cortical microtubule cytoskeleton in regulating plant cell growth and divisionBela Mulder AMOLF Netherlands14 55 15 10ERK activation waves are key drivers in the mechanical cell competition that leads to collective onslaught of bacterially infected cellsLara Hundsdorfer University of T bingen Germany15 10 15 25Bacterial adhesion on the apical cell surface modifies the traction force field on the basal side through a new actomyosin structure called ancreopodiaDaria Bonazzi Institut Pasteur France15 25 15 55Coffee Break and Meet the speakers 15 55 16 25Multiciliated cells use filopodia to probe tissue mechanics during epithelial integration in vivoJakub Sedzinski Novo Nordisk Foundation Center for Stem Cell Medicine reNEW Denmark16 25 16 40Dual roles of catenin in signaling and cell cell junction maintenance in the intestinal epitheliumAndrew Clark University of Stuttgart Germany16 40 16 55The stability of Arp2 3 nucleated actin filamentsLuYan Cao The Francis Crick Institute United Kingdom16 55 17 25Cellular Biophysics of Membranes Remodeling and Rupture Lessons from NETosisHawa Racine Thiam Stanford University USA Remote speaker 17 25 17 55Flash talks 2 minutes 1 slide per talk 71 Xinwen Miao 73 Alexander Dulebo 75 Priyanka Roy 77 Jan Sabo 79 Gautham Hari Sankara Narayana 81 Lan Jiang 83 Oscar Stassen 85 Joseph Vermeil 87 Hannes Vogler 89 Arash Yahyazadeh Shourabi and 91 Andrew Zhao17 55 19 25Poster Session 1 odd numbers 19 25 20 25Dinner in Canteen20 25 21 30Drinks in ATC Roof top lounge Day 3 Wednesday 14 June 2023 Time Europe Berlin Speaker09 00 12 00Session 4Chair Jakub Sedzinski Novo Nordisk Foundation Center for Stem Cell Medicine reNEW Denmark09 00 09 30Molecular mechanobiology of the extracellular matrixViola Vogel ETH Z rich Switzerland09 30 09 45Polarity driven three dimensional spontaneous rotation of a cell doubletQuentin Vagne University of Geneva Switzerland09 45 10 15Mechanobiology of tight junctionsSandra Citi University of Geneva SwitzerlandNot available on demand10 15 10 45Coffee Break and Meet the speakers10 45 11 00Interacting systems for complex cell wall patterns with special functionsEva Deinum Wageningen University Research The Netherlands11 00 11 15Membrane reshaping across the tree of lifeFelix Frey Institute of Science and Technology Austria Austria11 15 11 30Modelling macropinocytic cup formation and closure informed by lattice light sheet microscopy dataJudith Lutton University of Warwick United Kingdom11 30 12 00Inoviruses in the gut microbiota release without bacterial lysisCarolina Tropini The University of British Columbia Canada12 00 12 25Flash talks 2 minutes 1 slide per talk 50 Luca Andronico 52 Bin Qu 54 Golnar Kolahgar 56 Srishti Dar 58 Jenna Elliott 60 Sherman Foo 62 David Gomez 64 Kyojiro N Ikeda 66 Mengya Kong and 68 Jia Hui Li12 25 13 25Lunch13 25 16 55Session 5Chair Peter Bieling Max Planck Institute of Molecular Physiology Germany13 25 13 55The skin of a living cell a mechanoresponsive membraneSatyajit Mayor National Centre for Biological Sciences India13 55 14 10Cytoskeleton mediated spatial accommodation shapes lateral root morphogenesisDorothee St ckle University of Zurich Switzerland14 10 14 25Mechanisms and mechanics at the cell surface driving epithelial tube formationMatteo Rauzi University C te d Azur CNRS Inserm iBV Nice France14 25 14 55Bacteria mechanosense surfaces to guide motility and biofilm formationAlexandre Persat EPFL Switzerland14 55 15 25Coffee Break and Meet the speakers15 25 15 55The evolutionary mechanics of microbial morphogenesisEnrique Rojas New York University USA15 55 16 10Fast remodeling of surface cytoskeleton underlie phenotypic switches in the closest relatives of animalsThibaut Brunet Institut Pasteur FranceNot available on demand16 10 16 25Nanoscale Membrane Topography Engineering in cells in vitro and in between Wenting Zhao Nanyang Technological University Singapore16 25 16 55Interplay between cell surface mechanics and contact dependent signalingAnna Erzberger EMBL Heidelberg Germany16 55 17 20Flash talks 2 minutes 1 slide per talk 72 Marie Muenkel 74 Nicolas Roby 76 Francois Fagotto 78 Julio Cesar Sanchez Rendon 80 Annika Sa 82 Vui Yin Seow 84 Abdul Basith Tanari 86 Filipe Vicente 88 Steve Caplan and 90 Cheng han Yu17 20 18 50Poster Session 2 even numbers 18 50 20 20Conference Dinner20 20 23 00Conference Party Day 4 Thursday 15 June 2023 Time Europe Berlin Speaker09 15 14 15Session 6Chair Anna Erzberger EMBL Heidelberg Germany and Ewa Paluch University of Cambridge UK09 15 09 45More than the sum How does a composite interface govern function at the cell surface Alba Diz Mu oz EMBL Heidelberg GermanyNot available on demand09 45 10 00PPP2R1A Regulates Migration Persistence through the NHSL1 containing WAVE Shell ComplexYanan Wang cole Polytechnique France10 00 10 15Chitosan glycerol blended micro structured membranes for the enhancement of peripheral nerve regenerationLuca Scaccini Scuola Normale Superiore Italy10 15 10 30Organic semiconductors for modulation of mechano sensitive channels in MDCK cellsVanessa Spagnolo Istituto Italiano di Tecnologia Italy10 30 10 45Staying in touch septate junctions and epithelial sampling in the Drosophila cropJason Millington Stanford University United States of America10 45 11 15Coffee Break and Meet the speakers 11 15 11 45The final cut ESCRT III in cell division from archaea to eukaryotesBuzz Baum MRC Laboratory of Molecular Biology UK11 45 12 00 Cracking the gut epithelium junctional rupture at the interface of two different cell typesJustine Creff Molecular Cellular and Developmental Biology France12 00 13 00Lunch13 00 13 30Coordinating morphogenetic events supracellular actomyosin cables as mechanical insulatorsKatja R per MRC Laboratory of Molecular Biology UK13 30 13 45Hechtian strands The threads for mechanosensing in plant cells Denise Arico Laboratoire de Recherche en Sciences V g tales Universit de Toulouse CNRS Laboratoire Reproduction et D veloppement des Plantes ENS Lyon INRAe France13 45 14 15The molecular mechanism of force feedback in lamellipodial actin networksDyche Mullins University of California San Francisco USA14 15 14 30Closing Remarks and Poster Prize14 30 14 45Departures Practical information Registration fees and abstract submission On site registration fees include admission conference materials COVID 19 safety measures meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Virtual registration fees include access to all of the talks livestreamed and on demand and facility to submit questions On site Academia 700On site PhD Student 600On site Industry 900Virtual Academia 200Virtual PhD Student 150Virtual Industry 250 A letter to support your visa application will be issued on request once payment of the registration fee is confirmed We recommend that you book your visa appointment as soon as possible to avoid any delay with your visa application Accredited journalists may be eligible to register for complimentary press registration Registrants may be required to provide accreditation or equivalent proof of press membership after registration Please contact Maria Bacadare for more information Please note that we do not offer complimentary registrations for editors of scientific journals Confirmation and payment Registration will be on a first come first served basis Your place can only be confirmed after payment of the registration fee If you are added to our waiting list please consider taking advantage of our offerings to participate virtually On site participants Types of payments accepted are international bank transfers and credit card payments Virtual participants We are only able to accept card payments In exceptional cases we can accept bank transfers Please contact events embl de for details Abstract submission Only participants registering to attend the on site event are eligible to submit an abstract Abstracts will not be accepted from virtual participants After registration you can submit your abstract via a separate link that will be provided in the email confirmation Alternatively you can access the link on the confirmation page directly after registering The same login credentials are used for both processes Please note Abstract body The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised Title The title should not exceed 20 words Only the first word of the title should start with a capital letter and the rest should be lowercase Authors and affiliations Please fill in the author s details as requested in the online form The compulsory fields are First Name Last Name Organisation Name Affiliation or Company Country and Email Kindly mark only one author in the role of First Author and please don t forget to indicate who will be the Presenter Please enter your co authors correctly via the system by adding accounts together with their organisation institute Do not copy paste them into the body of the abstract text as they will not be indexed in the abstract book Presentation types When submitting your abstract you can apply for an oral or poster presentation A selection process will take place with the results announced 2 3 weeks after the abstract submission deadline For detailed instructions on how to submit a conference abstract follow the instructions provided in this video Please check our FAQs pages for further information on how to submit an abstract Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of both registration fee waivers and travel grants These are available for on site participants at EMBL Conferences and EMBO EMBL Symposia and for on site and virtual participants at EMBO Workshops We are currently working on securing funding for all virtual participants and ask that you please apply for financial assistance for both on site and virtual participation Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course or conference Travel grant The travel grant will cover the cost of travel to an on site event airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from within Europe up to 1000 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from outside Europe up to 500 for any participant travelling to an EMBO Workshop up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Workshop up to 700 for any participant working in Croatia Czech Republic Estonia Greece Hungary Italy Lithuania Luxembourg Poland Slovenia and Turkey travelling to an EMBO Workshop Registration fees are only covered for EMBO Workshops The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Application On site participants You may apply for financial assistance when submitting your abstract In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Virtual participants If you are attending virtually you can apply for financial assistance in the submission portal by the abstract deadline Read the instructions on how to apply for financial assistance Only submissions for financial assistance will be accepted Presentation abstracts cannot be submitted here and will be declined In your application you will be asked to summarise your current work answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Selection The scientific organisers will select the recipients of all financial assistance during the abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details View our list of external funding opportunities and information on attending a conference as an event reporter For further information about financial assistance please refer to the FAQ page Accommodation and shuttles Accommodation is not included in the conference registration fee As further changes in our events are possible due to COVID 19 you should book flights trains and hotels with flexible options and favourable cancellation conditions The hotels below have rooms on hold for participants until Monday 15 May 2023 in some cases at special rates Please email the hotel directly quoting the booking code EES23 05 to confirm the exact price of the room Hotel AnlageHotel ibis HeidelbergPremier Inn Heidelberg CityHotel Bayrischer Hof ISG Hotel Staycity Aparthotel HeidelbergB B HotelLeonardo Hotel Heidelberg City CentreSteffi s Hostel HeidelbergExzellenz Hotel Boarding HouseMeininger HeidelbergHotel Vier Jahreszeiten HeidelbergHotel Holl nder Hof Hotel Monpti Conference shuttle buses Conference shuttle buses are free of charge for participants and depart from designated bus stops near the hotels to EMBL and back mornings and evenings Conference shuttle bus schedule The bus stops for this conference are Staycity Aparthotel Speyerer Str 7 Kurf rsten Anlage Opposite Main Train Station Premier Inn Kurf rsten Anlage 23 Leonardo Hotel Heidelberg City Center Bergheimer Str 63 Neckarm nzplatz Heidelberg Tourist Information Peterskirche Bus stop ISG Hotel Im Eichwald 19 View Conference shuttle bus stops and hotels in a larger map Please note that not every bus stop will be used for every event Further details Address EMBL Meyerhofstra e 1 69117 Heidelberg Germany For further information on getting to EMBL Heidelberg visit Public Transportation to the Venue For information about accommodation and local transportation please refer to the FAQ page On site information Catering All meals and coffee breaks are included in the registration fee Our catering staff will prepare a wide variety of vegetarian meals meat and fish dishes soups pasta fresh fruit and vegetables as well as a variety of desserts Please wear your badge at all times when serving yourself No food or drinks are allowed in the auditorium Charging lockers There are lockers available next to the stairs leading down into the Auditorium You will find some of those equipped with sockets to charge your smartphone tablet etc Electricity and charging station In most places the electricity is 220 volts AC 50 cycles An adaptor and a plug that fits the German socket may be needed for your appliances laptop i e American Japanese etc A USB charging station for electronic devices is available at the registration desk EMBL merchandise If you are interested in purchasing an EMBL souvenir products presented in the glass display in the registration area please ask at the registration desk for more information Health and safety notes Please read EMBL s COVID 19 safety policy for on site events Do not smoke in any EMBL building Eating and drinking is prohibited in the Auditorium and all laboratories Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required The first aid room is located next to the ATC Registration Desk room 10 205 Dial the Emergency number 222 from any EMBL internal phone only Where is the accident What happened How many injured Emergency number 06221 387 7821 from mobile phones Please report all accidents to the conference officer at the registration desk In case of fire Press the nearest fire alarm button or the Emergency number 222 from any internal phone A loud fire alarm will go off if an evacuation is required On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting points Do not use the lifts Beyond first aid Please remember to bring your own medication if needed to the conference Note that the next pharmacy is a 4 minute drive from the EMBL but for many medications you will be required to see a doctor to get a prescription Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg In any case the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary Internet Wi Fi is available everywhere on the premises no password required just log on to ATC Guest The eduroam network secure world wide roaming access service developed for the international research and education community is also available Lost and found Lost and Found are kept at the registration desk until the end of the conference Luggage There are lockers available on site to store your luggage which require a 2 EURO coin to operate There is another luggage room on level E0 which is free to use but remains unlocked during the conference Nursing room There is a nursing room available in the ATC Rooftop Lounge on level A29 Photography During the conference an EMBL Photographer may be taking photographs If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Printing We can help printing your boarding passes train ticket Please send it to events embl de and collect your print outs at the registration desk Room for prayer yoga and meditation There is a room for prayer mediation and yoga located on level E0 behind the Auditorium Please be respectful of other participants using the room Sightseeing A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing Travel to and from the venue During the event we provide conference shuttle buses to and from EMBL In addition there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time Information on the conference shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page Useful German expressions HelloHalloGoodbyeAuf WiedersehenGood morningGuten MorgenGood afternoonGuten TagGood eveningGuten AbendGood nightGute NachtI m sorryTut mir leidExcuse me Entschuldigen SieHow are you Wie gehts I m fine thanks And you Mir geht es gut danke und dir Ihnen What is your nameWie heisst du Wie heissen Sie My name isIch heisseDo you speak EnglishSprechen Sie Englisch I don t understandIch verstehe nichtPlease speak more slowlyK nnen Sie bitte langsamer sprechenThank youDankesch nWhere is the toilet Wo ist die Toilette Please call me a taxiBitte rufen Sie mir ein TaxiHow do I get to Wie komme ich zum zur A beer two beers pleaseEin Bier zwei Bier bitteA glass of red white wine pleaseEin Glas Rot Weisswein bitteThe menu pleaseDie Speisekarte bitteIs there a local speciality Gibt es eine Spezialit t aus dieser Gegend I m VegetarianIch bin VegetarierIt was deliciousEs war hervorragendThe bill pleaseDie Rechnung bitteI have a headacheIch habe KopfschmerzenI have a sore throatIch habe HalsschmerzenMy stomach hurtsIch habe MagenschmerzenI m allergic toIch bin allergisch gegenI need a doctor who speaks EnglishGibt es einen Arzt der Englisch spricht Where is the nearest COVID 19 test centre Wo ist das n chste COVID 19 Testzentrum Virtual participation What s included Access to all the livestreamed talks Video library of the recorded talks during and after the event Facility to submit questions Please note that only on site participants are able to submit abstracts and participate in the poster sessions Event platform We are using an event platform for this conference More information about the platform will be shared ahead of the conference Guidelines Do not broadcast the conference to unregistered participants You are encouraged to tweet and post about the event Tweet unless the speaker specifically says otherwise but be mindful of unpublished data Please do not capture transmit or redistribute data presented at the meeting Additional information can be found in our Code of Conduct Health and well being It is important to stay healthy and move around especially when you are attending an event virtually We have put together a few coffee break stretches and yoga videos in the conference platform for you to enjoy during the event How to ask questions Please use the Q A function in the event platform If you have any other questions you can go to the Help Desk in the event platform Click on more on the top menu and click Help Desk Time zone The programme is planned based on the Europe Berlin time zone unless otherwise stated Please take your time zone into consideration when planning your attendance Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page COVID 19 related questions COVID 19 information for on site events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Bronze sponsor Event sponsor Molecular Machines Industries MMI Media partners EMBO Journal an EMBO Press journal FEBS Letters a FEBS Press journal International Union of Biochemistry and Molecular Biology Journal of Cell Science a The Company of Biologists journal Open Biology a Royal Society journal Bio Essays a Wiley Online Library Advanced Biology a Wiley Online Library Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de About EMBO EMBL Symposia promote scientific communication and collaboration in the European research area They provide scientists with a platform to discuss and exchange ideas on forward looking topics and new developments in the life sciences Topics emphasise upcoming developments and the interdisciplinary nature of related fields Jointly funded and organised by EMBO and EMBL and complementary to their respective courses workshops and conference programmes the symposia promote scientific communication and collaboration All symposia are held in the EMBL Advanced Training Centre ATC in Heidelberg Germany or virtually Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9 Leaderboard 728 x90...

Alba Diz Muñoz, Zemer Gitai, KC Huang, Ewa Paluch

EMBO | EMBL Symposium

EMBL Heidelberg, Virtual

12 June - 16 June 2023

Summer school in bioinformatics

Edit

June 12, 2023 00:002023CourseEMBL-EBI

Description This course provides an introduction to the use of bioinformatics in biological research giving participants guidance for using bioinformatics in their work whilst also providing hands on training in tools and resources appropriate to their research Participants will initially be introduced to bioinformatics theory and practice including best practices for undertaking bioinformatics analysis data management and reproducibility To enable specific exploration of resources in their particular field of interest participants will then be divided into focused groups to work on a project Participants will be required to review some pre recorded material prior to the start of the course Group projects A major element of this course is a group project where participants will be placed in small groups to work together on a challenge set by trainers from EMBL EBI and external institutes This allows people to explore the bioinformatics tools and resources available in their area of interest and apply them to a set problem providing participants with hands on experience relevant to their own research The group work will culminate in a presentation session involving all participants on the final day of the course giving an opportunity for wider discussion on the benefits and challenges of working with biological data Groups are mentored and supported by the trainers who set the initial challenge but the groups will be responsible for driving their projects forward with all members expected to take an active role Groups are pre organised before the course and all group members will be sent some short homework in preparation for their project work prior to the start of the course Basic outlines of the projects on offer this year are given below In your application you must indicate your first and second choice of project based on which you think would benefit your research most Not all projects may be offered and final decisions on which projects will be run during the course will be made based on the number of applicants per project Most of the projects cover mammalian data sets however in many cases the methods and approaches taught are transferable to data from various species Group project one Genome variation across human populations Natural variation between individuals or between different human populations is a result of genome mutations throughout evolutionary history Some mutations may become fixed because of their beneficial effect while most drift among individuals During this project you will investigate genomic variation between two separate human populations of European and Asian descent Using sequence data from a number of individuals from each population you will use a range of bioinformatics tools to discover variants that exist between them In the second section of the project you will attempt to analyse the functional consequences of the variants you have identified attempting to find clinical association and linking them to phenotypes Project mentor Baron Koylass EMBL EBI Group project two Interpreting functional information from large scale protein structure data This project will introduce you to the wealth of publicly available data in the Protein Data Bank PDB and give you the opportunity to investigate how large subsets of structure data can be used to analyse protein features and determine function In the project you will learn how to identify relevant protein structures collate and interpret functional information and implement this process programmatically Project mentor Preeti Choudhary EMBL EBI Marcus Bage EMBL EBI Group project three Modelling cell signalling pathways Curating models of biological processes is an effective training in computational systems biology where the curators gain an integrative knowledge of biological systems modelling and bioinformatics You will learn to encode and simulate ordinary differential equation models of signalling pathways from a recent publication using user friendly software such as COPASI even without extensive mathematical background You will learn to perform in silico experiments new predictions and develop hypotheses Furthermore you will learn how to annotate models and re use pre existing models from open repositories such as BioModels Project mentors Rahuman Sheriff EMBL EBI Krishna Tiwari EMBL EBI Group project four Networks and pathways This project will cover typical bioinformatics analysis steps needed to put differentially expressed genes into a wider biological context You will start with gene expression data RNA seq to build an initial interaction network Next you will learn to combine public network datasets identify key regulators of biological pathways and explore biological function through network analysis You will get first hand experience in integration and co visualising with additional data and functional enrichment analysis All this helps to put the initial results into a previously known context and provide hypotheses for potential follow up experiments We will use Cytoscape Expression Atlas g Profiler StringDb among other tools We also may give a few R packages a try Project mentor Priit Adler University of Tartu Group project five Reusing FAIR Bioimage data an AI application Biological imaging is a rapidly growing field with a vast potential of re use for further scientific research and development Re use of bioimage data requires FAIR Findable Accessible Interoperable Reusable data by public repositories that support FAIR sharing such as the BioImage Archive This project aims to showcase one of many ways of reusing bioimage data by applying artificial intelligence AI models on selected datasets in the BioImage Archive In this project you will learn to search and download the extensive variety of data that is held in this publicly available data resource You will also use Jupyter Python notebooks to visualise image data in the archive and deploy AI models on selected datasets Project mentors Aybuke Kupcu Yoldas EMBL EBI Teresa Zulueta Coarasa EMBL EBI Additional information Please note that we will operate this course face to face at EMBL EBI in Hinxton Hybrid options are not currently available We reserve the right to change the format of this course or cancel it due to the ongoing coronavirus pandemic...

Sophie Spencer

EMBL-EBI

11 June - 16 June 2023

Quantitative proteomics: strategies and tools to probe biology

Edit

June 11, 2023 00:002023CourseEMBL Heidelberg

Description OverviewSpeakersProgrammePractical InformationSponsorsMedia kit Overview Please see EMBL s COVID 19 safety policy for testing and other requirements to attend this on site course Course overview This course will provide both theoretical and practical training in the use of quantitative proteomics Participants will learn the principles of the most frequently used data acquisition methods DDA DIA and targeted proteomics and proteomic quantification approaches label free SILAC and TMT The major aim of this course is to practically train the participants in the use of readily available bioinformatic tools as well as in the statistical interpretation of proteomic data in order to empower them to make informed decisions in their own research Audience This course is aimed at researchers who know the basics of proteomics and who want to get a deeper understanding of quantitative methodologies and at those who are familiar with wet lab proteomic experimentation but want to gain experience in bioinformatic data interpretation To enter the course a basic understanding of mass spectrometry based proteomics is beneficial Modules resources The principles of proteome quantification by stable isotope labeling SILAC and TMT label free and targeted proteomics Introduction how various types of mass spectrometers can be used for proteome quantification Computer training sessions using software tools for the analysis of various quantitative proteomic data types Lectures demonstrating the application of quantitative proteomics in biology clinical research and drug discovery Learning outcomes Understand the principles and use cases of quantitative proteomic methods Ability to design quantitative proteomic experiments including selection of the most appropriate hardware and software Ability to analyse quantitative proteomic data by various software tools Speakers Speakers trainers and staff Miriam Abele Technical University Munich Germany Tine Claeys Ghent University Belgium Dominic Helm German Cancer Research Center Germany Devon Kohler Northeastern University USA Jeroen Krijgsveld German Cancer Research Center and Heidelberg University Germany Janne Lehti Karolinska Institute Sweden Kathryn Lilley University of Cambridge UK Fan Liu Leibniz Forschungsinstitut f r Molekulare Pharmakologie Germany Christina Ludwig Technical University Munich Germany Lennart Martens Ghent University Belgium Julia Mergner Technical University Munich Germany Shabaz Mohammed University of Oxford UK Alexey Nesvizhskii University of Michigan Medical School USA Ilaria Piazza Max Delbr ck Center Germany Daniel Polasky University of Michigan Medical School USA Pablo Andres Rivera Mej as EMBL Heidelberg Germany Mikhail Savitski EMBL Heidelberg Germany Frank Stein EMBL Heidelberg Germany Olga Vitek Northeastern University USA Scientific organisers Jeroen Krijgsveld German Cancer Research Center and Heidelberg University Germany Christina Ludwig Technical University Munich Germany Mikhail Savitski EMBL Heidelberg Germany Course organisers Aline Schnieder Course and Conference Officer EMBL Heidelberg Germany Swetlana Krez Training Lab Technician EMBL Heidelberg Germany Programme Got something to say Tweet it with EMBOQuantPro Some speakers may need to join virtually to give their lecture or Q A and the programme is subject to change Day 1 Sunday 11 June 2023 Time Europe Berlin SessionLocation13 00Bus to EMBL ATCISG Hotel13 30 14 00Registration welcome and housenotesCourtyard Room A B14 00 14 45Introduction Quantitative proteomics for biologyJeroen Krijgsveld German Cancer Research Center DKFZ University of Heidelberg GermanyChristina Ludwig Technical University Munich GermanyMikhail Savitski EMBL Heidelberg GermanyCourtyard Room A B14 45 16 00Lecture Peptide chromatography in proteomics remote lecture Shabaz Mohammed University of Oxford UKCourtyard Room A B16 00 16 30Coffee BreakCourtyard Room A B16 30 17 30Flash talks 1 odd numbers Courtyard Room A B17 30 19 00Poster Session odd numbers with drinks and snacksHelix B19 00 20 00DinnerEMBL Canteen20 00Bus to ISG HotelATC entrance Day 2 Monday 12 June 2023 Time Europe Berlin SessionLocation08 40Bus to EMBL ATCISG Hotel09 00 09 05Overview of the dayCourtyard Room A B09 05 10 05Lecture MS technologiesDominic Helm German Cancer Research Center DKFZ GermanyCourtyard Room A B10 05 11 20Lecture Peptide and protein identificationLennart Martens Ghent University BelgiumCourtyard Room A B11 20 11 35Coffee BreakCourtyard Room A B11 35 12 35Practical session 1 Peptide and protein identificationLennart Martens Ghent University BelgiumMiriam Abele Technical University Munich GermanyTine Claeys Ghent University BelgiumChristina Ludwig Technical University Munich GermanyJulia Mergner Technical University Munich GermanyComputer Training Lab12 35 13 35LunchEMBL Canteen13 35 15 05Practical session 1 cont Peptide and protein identificationLennart Martens Ghent University BelgiumMiriam Abele Technical University Munich GermanyTine Claeys Ghent University BelgiumChristina Ludwig Technical University Munich GermanyJulia Mergner Technical University Munich GermanyComputer Training Lab15 05 16 20Coffee break and Lab tourCourtyard Room A B Proteomics Core Facility16 20 17 20Flash talks 2 even numbers Courtyard Room A B17 20 18 20Application talk 1 Cancer proteogenomicsJanne Lehti Karolinska Institute SwedenCourtyard Room A B18 20 19 20DinnerEMBL Canteen19 20 20 50Poster Session even numbers with drinks and snacksHelix B20 50Bus to ISG HotelATC entrance Day 3 Tuesday 13 June 2023 Time Europe Berlin SessionLocation08 40Bus to EMBL ATCISG Hotel09 00 09 05Overview of the dayCourtyard Room A B09 05 10 35Lecture Introduction to label free quantification by DIA SWATHChristina Ludwig Technical University Munich GermanyCourtyard Room A B10 35 11 05Coffee BreakCourtyard Room A B11 05 12 35Practical session 2 Label free protein quantification by DIA SWATHMiriam Abele Technical University Munich Germany Jeroen Krijgsveld German Cancer Research Center DKFZ University of Heidelberg Germany Christina Ludwig Technical University Munich Germany Julia Mergner Technical University Munich Germany Mikhail Savitski EMBL Heidelberg GermanyComputer Training Lab12 35 13 35LunchEMBL Canteen13 35 15 35Practical session 2 cont Label free protein quantification by DIA SWATHMiriam Abele Technical University Munich Germany Jeroen Krijgsveld German Cancer Research Center DKFZ University of Heidelberg Germany Christina Ludwig Technical University Munich Germany Julia Mergner Technical University Munich Germany Mikhail Savitski EMBL Heidelberg GermanyComputer Training Lab15 35 16 05Coffee BreakCourtyard Room A B16 05 17 05Application talk 2 Spatial and sub cellular proteomicsKathryn Lilley University of Cambridge UKCourtyard Room A B17 05 18 05Application talk 3 Versatility of SILAC labeling to understand proteome dynamicsJeroen Krijgsveld German Cancer Research Center DKFZ University of Heidelberg GermanyCourtyard Room A B18 05 19 00DinnerEMBL Canteen19 00Bus to ISG HotelATC entrance Day 4 Wednesday 14 June 2023 Time Europe Berlin SessionLocation08 40Bus to EMBL ATCISG Hotel09 00 09 05Overview of the dayCourtyard Room A B09 05 10 05Lecture Introduction of MSFragger for analysis of TMT dataAlexey Nesvizhskii University of Michigan USACourtyard Room A B10 05 12 05Practical session 3 Analysis of TMT and PTM data with MSFraggerAlexey Nesvizhskii University of Michigan USADaniel Polasky University of Michigan USAChristina Ludwig Technical University Munich GermanyMikhail Savitski EMBL Heidelberg GermanyFrank Stein EMBL Heidelberg GermanyComputer Training Lab12 05 13 05LunchEMBL Canteen13 05 14 35Practical session 3 cont Analysis of TMT and PTM data with MSFraggerAlexey Nesvizhskii University of Michigan USADaniel Polasky University of Michigan USAChristina Ludwig Technical University Munich GermanyMikhail Savitski EMBL Heidelberg GermanyFrank Stein EMBL Heidelberg GermanyComputer Training Lab14 35 15 05Coffee BreakCourtyard Room A B15 05 16 05Open discussion Agenda to be set by course participantsCourtyard Room A B16 05 17 05Application talk 4 Stability proteomicsMikhail Savitski EMBL Heidelberg GermanyCourtyard Room A B17 05 18 05Meet the speaker session with drinks and snacksCourtyard Room A B18 05Free eveningBus downtown via ISG HotelEMBL bus stop Day 5 Thursday 15 June 2023 Time Europe Berlin SessionLocation08 40Bus to EMBL ATCISG Hotel09 00 09 05Overview of the dayCourtyard Room A B09 05 10 35Lecture Introduction to statistical analysis of proteomics dataOlga Vitek Northeastern University USACourtyard Room A B10 35 11 05Coffee BreakCourtyard Room A B11 05 12 35Practical session 4 Statistical analysis of proteomics data using MSStatsOlga Vitek Northeastern University USAMiriam Abele Technical University Munich GermanyDevon Kohler Northeastern University USAChristina Ludwig Technical University Munich GermanyJulia Mergner Technical University Munich GermanyComputer Training Lab12 35 13 35LunchEMBL Canteen13 35 15 35Practical session 4 cont Statistical analysis of proteomics data using MSStatsOlga Vitek Northeastern University USAMiriam Abele Technical University Munich GermanyDevon Kohler Northeastern University USAChristina Ludwig Technical University Munich GermanyJulia Mergner Technical University Munich GermanyComputer Training Lab15 35 16 05Coffee breakCourtyard Room A B16 05 17 05Application talk 5 Allosteric proteomicsIlaria Piazza MDC Berlin GermanyCourtyard Room A B17 05 17 45Bus downtown via ISGEMBL bus stop17 45 19 15Guided city tour19 30 21 30Course dinner Day 6 Friday 16 June 2023 Time Europe Berlin SessionLocation08 40Bus to EMBL ATCISG Hotel09 00 09 05Overview of the dayCourtyard Room A B09 05 10 05Application talk 6 Structural interactomicsFan Liu Leibniz Forschungsinstitut f r Molekulare Pharmakologie FMP GermanyCourtyard Room A B10 05 12 35Breakout sessions Discussion in groupsCourtyard Room A B Flex Lab A B12 35 13 35LunchEMBL Canteen13 35 15 35Presentations from breakout session Panel discussionCourtyard Room A B15 35 16 05Recap and FarewellCourtyard Room A B16 05Bus to train station via ISGATC entrance Practical Information Registration fees and motivation letter The course is limited to 24 participants For selection purposes please note that your application will not be considered without a letter of motivation Registration Registration fees include admission course materials COVID 19 safety measures meals and coffee breaks This EMBO course includes accommodation and transportation to and from the ISG Hotel to the venue Academia 500PhD Student 500Industry 1000 A letter to support your visa application will be issued on request once payment of the registration fee is confirmed We recommend that you book your visa appointment as soon as possible to avoid any delay with your visa application Confirmation and payment The registration fee should be paid only after acceptance to the course The results will be announced approximately 2 3 weeks after the application deadline Motivation letter submission After you have logged in and successfully registered you will receive an email asking you to submit your motivation letter Click on the link provided and enter your motivation letter in the text box provided Alternatively you can submit your motivation letter by clicking on the link on the confirmation page directly after registering Instructions Include your relevant skills experience and qualifications showing why you would be suitable for the course Explain why you would like to attend including what you can contribute and how you think you will benefit from the course Please note The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised For detailed instructions please watch our video on how to submit a course motivation letter Further details For further information about registration and motivation letter submission please refer to the FAQ page Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of both registration fee waivers and travel grants Availability is limited to participants attending on site EMBL Courses and virtual or on site EMBO Practical Courses in Heidelberg and will be indicated during the motivation letter submission process Your place in the course is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course Travel grant The travel grant will cover the cost of travel airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Course within Europe up to 1000 for participants travelling to an EMBL Course from outside Europe up to 500 for any participant travelling to an EMBO Practical Course up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Practical Course up to 700 for any participant working in Croatia Czech Republic Estonia Greece Hungary Italy Lithuania Luxembourg Poland Slovenia and Turkey travelling to an EMBO Practical Course Registration fees are only covered for EMBO Practical Courses The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant EMBO Practical Courses only For EMBO Practical Course participants with children there is the possibility to apply for a childcare grant to offset child care costs incurred by participants or speakers when participating at a course Eligible costs include fees for a babysitter or child care facility travel costs for a caregiver or travel costs for taking the child to the meeting etc Please note that priority will be given to early stage researchers A maximum amount of 500 can be awarded per participant applying for an EMBO childcare grant Boehringer Ingelheim Fonds travel grant Applies to selected courses only Availability will be indicated during the motivation letter submission process This grant covers costs related to your attendance at the course registration travel and accommodation costs The grant is restricted to PhD students and postdocs who conduct basic biomedical research Whether you are eligible to apply for a travel grant depends on when you received your university entrance qualification e g Abitur A Levels High School Diploma Final State Examination for PhD and MD students as well as graduates the university entrance qualification must not have been obtained more than 11 years ago at the time of the envisaged course for postdocs the university entrance qualification must not have been obtained more than 13 years ago at the time of the envisaged course Application You may apply for financial assistance when submitting your motivation letter for courses In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application For the Boehringer Ingelheim Fonds Travel Grant there is a pre application question during the motivation letter submission process and if selected you will be requested to complete a standard form and documentation consisting of your travel expense estimation Selection The scientific organisers will select the recipients of all financial assistance during the motivation letter selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the course Selection is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details See our list of external funding opportunities and for further information about financial assistance please refer to the FAQ page Accommodation and shuttles Hotel Accommodation has been pre booked for you at the ISG Hotel for the default dates of 11 to 16 June 2023 5 nights Please note that the course registration fee includes coverage of accommodation costs in twin rooms including breakfasts for your stay at the ISG In case you would like to have a single room please let us know and please note that you will be required to pay an additional cost of 31 per night This should be paid by you directly to the ISG during your stay Any additional nights need to be booked and paid for by you We recommend that all course participants stay at the ISG Hotel which is the dedicated hotel for the course Local transport Shuttle buses will go from the ISG Hotel to EMBL and back mornings and evenings A bus schedule and location of the bus stops will be made available prior to the meeting Further details Address EMBL Heidelberg Meyerhofstra e 1 69117 Heidelberg GermanyFor further information on getting to EMBL Heidelberg visit our Travel Information page For enquiries about accommodation and local transportation please refer to the FAQ page Technical requirements and event software Event software The EMBL eCampus learning platform will be used to collaborate communicate and network with all of the course participants All participants will receive information on how to join shortly before the course We recommend using Chrome Safari or Mozilla Firefox browsers for eCampus Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page COVID 19 related questions COVID 19 information for on site events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Event supporter Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other events or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9...

Jeroen Krijgsveld, Christina Ludwig, Mikhail Savitski

EMBO Practical Course

EMBL Heidelberg

Edit

May 24, 2023 15:302023WebinarVirtual

Description Genomic variation can impact normal biological function in complex ways and so understanding variant effects requires a broad range of data to be coherently assimilated Understanding variation in proteins offers unique opportunities over and above diagnostics such as identifying drug targets and synthetic biology applications however it also poses unique challenges which is why most missense variation remain of unknown effect ProtVar is a new updated and maintained human variant annotation and assessment web tool which offers users unparalleled flexibility and ease of accessibility and integration It combines data and analyses from a plethora of resources to bring together genomic protein sequence functional as well as structural insights and predictions to better understand the potential effects of missense variation on humans This webinar will cover the variety of data types which can be used to access ProtVar and the ways in which such data can be submitted It will also cover the annotation and prediction types available as well as the visualisations available and the methods by which data can be retrieved...

Virtual

23 May 2023

Edit

May 21, 2023 00:002023CourseEMBL Heidelberg

Description OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview Course overview This course will teach the biological researchers how to analyse biological data sets using open source software Most of the analysis will be performed with docker4seq and rCASC packages which was developed to facilitate the use of computing demanding applications in the field of NGS data analysis Docker4seq and rCASC packages use docker containers that embed demanding computing tasks e g short reads mapping into isolated containers This approach provides multiple advantages the user does not need to install all the software on its local server the results generated by different containers can be organised in pipelines and reproducible research is guarantee by the possibility of sharing the docker images used for the analysis Computers for hands on exercises will be provided along with demo data sets Audience This course was developed for biological researchers as the intended audience Basic knowledge of massively parallel sequencing MPS is desirable however R coding skills and deep knowledge of statistics are not necessary Modules Resources Tools for RNA seq and single cell RNA seq data analysis Experimental design RNAseq scRNAseq Quality control RNAseq scRNAseq Normalisation and data reformatting RNAseq scRNAseq Basic statistics RNAseq Selecting differentially regulated genes microRNAs RNAseq Multiple testing RNAseq Dimensionality reduction scRNAseq Clustering RNAseq scRNAseq Biological interpretation RNAseq scRNAseq Learning outcomes Understand the importance of experimental design in order to ask sensible biological questions Assess the quality of your data Perform normalisation and reformatting procedures Complete basic statistical tests on Next Generation Sequencing NGS data Understand some of the problems encountered when analysing data What past participants say about this course My research focus is on RNA sequencing infectious diseases and next generation sequencing Attending this course helped me understand the basics got me career advice and extended my network Overall it made me a better researcher Abhay Deep Pandey Translational Health Science And Technology Institute India Excellent course on the complete spectrum of RNA Seq I would highly recommend this course to all biologists Issaac Rajan King Abdullah University of Science and Technology Saudi Arabia Speakers Speakers trainers and staff Marco Beccuti University of Turin Italy Vladimir Benes EMBL Heidelberg Germany Raffaele Calogero University of Turin Italy Francesca Cordero University of Turin Italy Maria L Ratto University of Turin Italy Scientific organisers Marco Beccuti University of Turin Italy Vladimir Benes EMBL Heidelberg Germany Raffaele Calogero University of Turin Italy Francesca Cordero University of Turin Italy Course organisers Inna B sselmann Course and Conference Manager EMBL Heidelberg Germany Irena Provaznikova Training Lab Technician EMBL Heidelberg Germany Programme Got something to say Tweet it with EMBLDataAnalysis Some pre course work such as watching pre recordings protocol reading and computational exercises with estimated time 0 10 hours will be required and will be shared in advance of the course Some speakers may need to join virtually to give their lecture or Q A and the programme is subject to change All times in the programme below are shown as the time in Europe Berlin The preliminary programme is a draft and is subject to change Day 1 Sunday 21 May 2023 Time Berlin Europe SpeakerLocation13 30EMBL shuttle bus from ISG to EMBLISG Hotel entrance14 00 14 30Arrival welcome course overview and safety briefingVladimir Benes EMBL Heidelberg GermanyInna B sselmann EMBL Heidelberg GermanyIrena Provaznikova EMBL Heidelberg GermanyCourtyard Room A B14 30 15 00Participants flash talksCourtyard Room A B15 00 16 00RNA seq cool but is it that simple Vladimir Benes EMBL Heidelberg GermanyCourtyard Room A B16 00 16 30Coffee BreakCourtyard Foyer16 30 18 00RNA seq cool but is it that simple Vladimir Benes EMBL Heidelberg GermanyCourtyard Room A B18 00 19 00DinnerEMBL Canteen19 00EMBL shuttle bus to ISG HotelATC Entrance Day 2 Monday 22 May 2023 Time Berlin Europe SpeakerLocation08 40Embl shuttle bus from ISG to EMBLISG Hotel entrance09 00 10 00R pills theory and practiceMarco Beccuti University of Turin ItalyComputer Training Lab10 00 10 30Coffee BreakATC Foyer10 30 11 00Experimental designRaffaele Calogero University of Turin ItalyComputer Training Lab11 00 12 00Docker4seq rCASC 4SeqGUI overviewRaffaele Calogero University of Turin ItalyComputer Training Lab12 00 13 00LunchEMBL Canteen13 00 13 30Docker container and reproducibilityMarco Beccuti University of Turin ItalyComputer Training Lab13 30 14 30QC bulkRaffaele Calogero University of Turin ItalyComputer Training Lab14 30 15 00Coffee BreakATC Foyer15 00 16 00QC single cellsRaffaele Calogero University of Turin ItalyComputer Training Lab16 00 17 30R pills theory and practiceMarco Beccuti University of Turin ItalyComputer Training Lab17 30 18 30Social programme Facility tour18 30 20 10DinnerEMBL Canteen20 15EMBL shuttle bus to ISG HotelATC Entrance Day 3 Tuesday 23 May 2023 Time Berlin Europe SpeakerLocation08 40EMBL shuttle bus from ISG to EMBLISG Hotel entrance09 00 10 30R pills theory and practiceMarco Beccuti University of Turin ItalyComputer Training Lab10 30 11 00Coffee BreakATC Foyer11 00 12 30Counting reads and data reductionRaffaele Calogero University of Turin ItalyComputer Training Lab12 30 13 30LunchEMBL Canteen13 30 15 00Counting reads and data reductionRaffaele Calogero University of Turin ItalyComputer Training Lab15 00 16 00Counting reads miRNAFrancesca Cordero University of Turin ItalyComputer Training Lab16 00 16 30Coffee BreakATC Foyer16 30 18 00ExercisesComputer Training Lab18 00 19 00R pills theory and practiceMarco Beccuti University of Turin ItalyComputer Training Lab19 00 20 30DinnerEMBL Canteen20 30EMBL shuttle bus to ISG HotelATC Entrance Day 4 Wednesday 24 May 2023 Time Berlin Europe SpeakerLocation08 40Hoffmann Bus from ISG to EMBLISG Hotel entrance09 00 10 00Differential expression analysis for bulk RNAseqRaffaele Calogero University of Turin ItalyComputer Training Lab10 00 11 00Sub population discovery in single cell RNAseq clusteringRaffaele Calogero University of Turin ItalyComputer Training Lab11 00 11 30Coffee BreakATC Foyer11 30 12 30Differential expression analysis for multiple groups ANOVA likeRaffaele Calogero University of TurinComputer Training Lab12 30 13 30Lunch and group photoEMBL Canteen13 30 15 00Exercises Bulk RNAseqComputer Training Lab15 00 16 00Exercises single cell RNAseqComputer Training Lab16 00 16 30Coffee BreakATC Foyer16 30 18 00R pills theory and practiceMarco Beccuti University of Turin ItalyComputer Training Lab18 00EMBL shuttle bus to restaurantATC Entrance19 00Social Dinner at Oskar Restaurant Day 5 Thursday 25 May 2023 Time Berlin Europe SpeakerLocation08 40Hoffmann Bus from ISG to EMBLISG Hotel entrance09 00 10 00R pills theory and practiceMarco Beccuti University of Turin ItalyComputer Training Lab10 00 11 00Mining differential expression results for bulk RNAseqRaffaele Calogero University of Turin ItalyComputer Training Lab11 00 11 30Coffee BreakATC Foyer11 30 12 30Depicting clusters specific biomarkers in single cell RNAseq dataFrancesca Cordero University of Turin ItalyComputer Training Lab12 30 13 30Lunch EMBL Canteen13 30 16 00ExercisesComputer Training Lab16 00 16 30Coffee BreakATC Foyer16 30 17 30ExercisesComputer Training Lab17 30 18 30R pills theory and practiceMarco Beccuti University of Turin ItalyComputer Training Lab18 30 20 00DinnerEMBL Canteen20 00EMBL shuttle bus to ISG HotelATC Entrance Day 6 Friday 26 May 2023 Time Berlin Europe SpeakerLocation08 40EMBL shuttle bus from ISG to EMBLISG Hotel entrance09 00 11 00 Individual exercises on bulk or single cell RNAseqRaffaele Calogero University of Turin ItalyMarco Beccuti University of Turin ItalyComputer Training Lab11 00 11 30Coffee BreakATC Foyer11 30 12 30Individual exercises on bulk or single cell RNAseqRaffaele Calogero University of Turin ItalyMarco Beccuti University of Turin ItalyComputer Training Lab12 30 13 30LunchEMBL Canteen13 30 16 00Individual exercises on bulk or single cell RNAseqRaffaele Calogero University of Turin ItalyMarco Beccuti University of Turin ItalyComputer Training Lab16 00 16 20Final remarksVladimir Benes Raffaele Calogero Marco BeccutiComputer Training Lab16 30Hoffmann shuttle bus to Heidelberg Train StationATC Entrance Practical information Registration fees and motivation letter The course is limited to 28 participants For selection purposes please note that your application will not be considered without a letter of motivation Registration Registration Fees include admission course materials COVID 19 safety measures meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Academia 690PhD Student 690Industry 1200 Confirmation and payment The registration fee should be paid only after acceptance to the course The results will be announced approximately 2 3 weeks after the application deadline Motivation letter submission After you have logged in and successfully registered you will receive an email asking you to submit your motivation letter Click on the link provided and enter your motivation letter in the text box provided Alternatively you can submit your motivation letter by clicking on the link on the confirmation page directly after registering Instructions Include your relevant skills experience and qualifications showing why you would be suitable for the course Explain why you would like to attend including what you can contribute and how you think you will benefit from the course Please note The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised For more detailed information follow the instructions provided in our video on how to submit a course motivation letter Further details For further information about registration and motivation letter submission please refer to the FAQ page Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of both registration fee waivers and travel grants Availability is limited to participants attending on site EMBL Courses and virtual or on site EMBO Practical Courses in Heidelberg and will be indicated during the motivation letter submission process Your place in the course is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course Travel grant The travel grant will cover the cost of travel airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Course within Europe up to 1000 for participants travelling to an EMBL Course from outside Europe up to 500 for any participant travelling to an EMBO Practical Course up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Practical Course up to 700 for any participant working in Croatia Czech Republic Estonia Greece Hungary Italy Lithuania Luxembourg Poland Slovenia and Turkey travelling to an EMBO Practical Course Registration fees are only covered for EMBO Practical Courses The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant EMBO Practical Courses only For EMBO Practical Course participants with children there is the possibility to apply for a childcare grant to offset child care costs incurred by participants or speakers when participating at a course Eligible costs include fees for a babysitter or child care facility travel costs for a caregiver or travel costs for taking the child to the meeting etc Please note that priority will be given to early stage researchers A maximum amount of 500 can be awarded per participant applying for an EMBO childcare grant Boehringer Ingelheim Fonds travel grant Applies to selected courses only Availability will be indicated during the motivation letter submission process This grant covers costs related to your attendance at the course registration travel and accommodation costs The grant is restricted to PhD students and postdocs who conduct basic biomedical research Whether you are eligible to apply for a travel grant depends on when you received your university entrance qualification e g Abitur A Levels High School Diploma Final State Examination for PhD and MD students as well as graduates the university entrance qualification must not have been obtained more than 11 years ago at the time of the envisaged course for postdocs the university entrance qualification must not have been obtained more than 13 years ago at the time of the envisaged course Application You may apply for financial assistance when submitting your motivation letter for courses In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application For the Boehringer Ingelheim Fonds Travel Grant there is a pre application question during the motivation letter submission process and if selected you will be requested to complete a standard form and documentation consisting of your travel expense estimation Selection The scientific organisers will select the recipients of all financial assistance during the motivation letter selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the course Selection is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details See our list of external funding opportunities and for further information about financial assistance please refer to the FAQ page Accommodation and shuttles Single rooms have been reserved for 6 nights 20 26 May 2023 at the ISG Hotel After the selection process selected participants should contact the hotel directly to make a booking booking code DAT23 01 We recommend that all course participants stay at the ISG Hotel which is the dedicated hotel for the course Local transport Shuttle buses will go from the ISG Hotel to EMBL and back mornings and evenings A bus schedule and location of the bus stops will be made available prior to the meeting Further details Address EMBL Heidelberg Meyerhofstra e 1 69117 Heidelberg GermanyFor further information on getting to EMBL Heidelberg visit our Travel Information page For enquiries about accommodation and local transportation please refer to the FAQ page Technical requirements and event software Technical requirements Below you will find the software and technical requirements for this course All software and hardware required for this course will be ready for you to use in our Computer Training Lab You will need admin rights to install the software required to access the virtual machines If you do not have admin rights please contact your technical support team in advance to make sure the software can be installed If you have a non standard HDMI port other than type A you need to bring an adaptor Keyboard and PC mouse are available for use with a standard USB port If you have a different port type such as USB C you will need to bring your own Event software The EMBL eCampus learning platform will be used to collaborate communicate and network with all of the course participants All participants will receive information on how to join shortly before the course We recommend using Chrome Safari or Mozilla Firefox browsers for eCampus Additional Information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page COVID 19 related questions COVID 19 information for onsite events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9...

Marco Beccuti, Vladimir Benes, Raffaele Calogero, Francesca Cordero

EMBL Course

EMBL Heidelberg

18 May - 19 May 2023

EMBL in Italy 2023: Chance and necessity-the indispensable role of curiosity-driven life sciences

Edit

May 18, 2023 00:002023Public EventOther

Description If you are not redirected please visit the event website...

Public conference

Other

17 May 2023

Annotating genomes with non-coding RNAs using Rfam and Infernal

Edit

May 17, 2023 15:302023WebinarVirtual

Description Rfam is a database of RNA families that currently contains over 4 000 families Together with the Infernal software Rfam is commonly used to annotate non coding RNAs in newly sequenced genomes In this webinar we will give an overview of the data available in Rfam and give a live demo of annotating a genome with non coding RNAs using Rfam and the Infernal software We will also discuss recent efforts to synchronise Rfam and miRBase...

Virtual

16 May - 18 May 2023

Practical biocuration

Edit

May 16, 2023 00:002023CourseEMBL-EBI

Description This three day course will introduce concepts vital to biocuration including metadata and ontologies the role of identifiers and extracting data from literature During the course there will be a focus on practical skills required by biocurators including programming for handling large biological datasets and querying databases Participants will have the opportunity to use these skills in a real life practical biocuration exercise during the group projects There will also be an opportunity to network with biocurators and learn more about their roles and data resources Group projects A major element of this course is a group project where participants will be placed in small groups to work together on a challenge set by trainers from EMBL EBI and external institutes This allows people to explore the role of biocurators and provide participants with hands on experience in biocuration The group work will culminate in a presentation session involving all participants on the final day of the course giving an opportunity for wider discussion in the whole course group Groups are mentored and supported by the trainers who set the initial challenge but the groups will be responsible for driving their projects forward with all members expected to take an active role Groups are pre organised before the course Basic outlines of the projects on offer this year are given below In your registration you must indicate your first and second choice of project Not all projects may be offered and final decisions on which projects will be run during the course will be made based on the number of applicants per project Group project Curating a protein complex In this project a new protein complex has been published and it is your role to find out as much information as possible about the complex Using literature and bioinformatics resources you will provide an overview of the protein complex including a full list of the complex members a description of the role of each protein and an overview of the role of the complex You will use resources such as UniProt PDB and EuropePMC Project mentor Michele Magrane Group project Exploring data and metadata from a genome wide association study The GWAS Catalog is a richly annotated database of human genome wide association studies which analyse associations between genetic variants and a disease or other trait of interest in a sample of individuals from a particular population In this mini project you will examine a GWAS publication in detail to extract information about the traits and samples under investigation and decide how to represent these metadata using standardised vocabularies and ontologies You will also use simple command line tools to look at a GWAS dataset and explore the role of standard formats and quality control in biocuration Project mentor Elliot Sollis Group project Using alignments to improve Rfam families a case of curating non coding RNA families Rfam is the database of non coding RNAs ncRNAs families These families are built out of a sequence alignment metadata describing the family and an infernal model Each family is built by curating alignments from publications or user submitted alignments In this project we will demonstrate the process of updating an existing family with an improved alignment We will examine the reports generated during curation In this process we will examine the phylogenetic distribution sequence alignment and model results to determine how the family should be updated to reflect the improved alignment Additionally we will show how to connect this information to resources like Wikipedia Project mentor Nancy Ontiveros...

Sophie Spencer

EMBL-EBI

15 May - 18 May 2023

Chromatin and epigenetics

Edit

May 15, 2023 00:002023ConferenceEMBL Heidelberg, Virtual

Description OverviewSpeakersProgrammePractical informationSponsorsMedia kitPre conference workshop Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Conference overview Epigenetics refers to heritable changes in gene expression that do not involve changes to the underlying DNA sequence At least three systems including DNA methylation histone modifications and non coding RNAs ncRNA are considered to play fundamental roles in epigenetic regulation Research over the last two decades has uncovered the role of epigenetics in a variety of human disorders and fatal diseases Moreover influence of age environment lifestyle and disease state on epigenetic states is being increasingly appreciated and actively studied This conference provides an international forum for cutting edge research in chromatin and epigenetics It provides the focal hub for people to present their research and exchange ideas Renowned speakers will cover the latest advances in the field Session topics Heterochromatin Developmental epigenetics Chromatin regulation Transcription and chromatin defects and diseases Nuclear architecture Single cell genomics What past participants say about the conference The conference was very thoughtfully organised and the subject matter allowed me to deepen my knowledge on many interesting levels It was a valuable experience that I would like to repeat in the future Magdalena University of Lodz Poland The training provided by EMBL was very fruitful and productive I would like to be a part of such training in future too and also like to recommend others to be part of it Dr Laxman Khanal BPKIHS Nepal Although online this conference was well organised with an overall great quality of talks about many novelties If I can I will definitely attend the next time maybe already on site Tobias Hohl Max Planck Institute of Immunology and Epigenetics Germany Please see EMBL s COVID 19 safety recommendations if attending the on site event Speakers Keynote Speaker Genevi ve Almouzni Institut Curie France Speakers Asifa Akhtar Max Planck Institute of Immunobiology and Epigenetics Germany Robin Allshire The University of Edinburgh UK Yehudit Bergman The Hebrew University of Jerusalem Israel Wendy Bickmore The University of Edinburgh UK Marc B hler Friedrich Miescher Institute for Biomedical Research Switzerland L Stirling Churchman Harvard Medical School USA Ibrahim Ciss Max Planck Institute of Immunobiology and Epigenetics Germany Rong Fan Yale University USA Mary Gehring Whitehead Institute for Biomedical Research USA Steven Henikoff Fred Hutchinson Cancer Research Center USA Nicola Iovino Max Planck Institute of Immunobiology and Epigenetics Germany Gary H Karpen University of California Berkeley USA Haruhiko Koseki RIKEN Japan Cornelis Murre University of California San Diego USA Paola Scaffidi Francis Crick Institute UK Anne Sch fer Max Planck Institute for Biology of Ageing Germany Efrat Shema Weizmann Institute of Science Israel Yang Shi Ludwig Cancer Research UK Alexander Stark Research Institute of Molecular Pathology Austria Sarah Teichmann Wellcome Sanger Institute UK Yi Zhang Howard Hughes Medical Institute Harvard Medical School and Boston Children s Hospital USA Scientific organisers Asifa Akhtar Max Planck Institute of Immunobiology and Epigenetics Germany Yehudit Bergman The Hebrew University of Jerusalem Israel Nicola Iovino Max Planck Institute of Immunobiology and Epigenetics Germany Gary H Karpen University of California Berkeley USA Sarah Teichmann Wellcome Sanger Institute UK Conference organiser Charlotte Courtney Course and Conference Officer EMBL Heidelberg Germany Programme Got something to say Tweet it EMBLChromatin Please note that the programme is subject to change Some speakers may need to join virtually to give their talk For registered participants recorded talks will be accessible on demand for 2 weeks after the end of the event unless indicated otherwise Day 1 Monday 15th May 2023 Time Berlin Europe SpeakerLocation12 30 14 30Arrival and RegistrationATC Registration Desk13 00 14 00Pre conference workshop Single molecule biology democratizing optical tweezers to enable your breakthrough discoveries in chromatin biology and epigenetics by LUMICKS B V registration required Courtyard room14 30 16 50Session 1 Chromatin RegulationChairs Yang Shi and Wendy Bickmore14 30 14 45Opening remarksNicola Iovino Max Planck Institute of Immunobiology and Epigenetics GermanyKlaus Tschira Auditorium14 45 15 10Genome wide mapping of chromatin dynamicsSteven Henifkoff Fred Hutchinson Cancer Research Center USAKlaus Tschira Auditorium15 10 15 25Repair of double strand breaks in Drosophila polycomb bodiesAniek Janssen University Medical Center Utrecht The NetherlandsKlaus Tschira Auditorium15 25 15 40A regulator of RNA Polymerase III embedded in the tDNA chromatin proteomeFred van Leeuwen Netherlands Cancer Institute The NetherlandsKlaus Tschira Auditorium15 40 16 05Epigenetic dynamics during plant reproductionMary Gehring Whitehead Institute for Biomedical Research USAKlaus Tschira Auditorium16 05 16 50Coffee Break Meet the Speakers of Day 1Steven Henikoff Mary Gehring Gary Karpen Robin Allshire Marc B hlerAuditorium Foyer16 50 19 05Session 2 HeterochromatinChairs Yehudit Bergman and Alexander Stark16 50 17 15New insights into formation organization and function of heterochromatin condensatesGary Karpen University of California Berkeley USAKlaus Tschira Auditorium17 15 17 30Coordination of chromatin functions and genome stability by the nuclear membrane protein Lem2Sigurd Braun Justus Liebig Universit t Gie en GermanyKlaus Tschira Auditorium17 30 17 45The bromodomain inhibitor JQ1 is a molecular glue targeting BRD4 to centromeric chromatinSamuel Corless Karlsruhe Institute of Technology KIT GermanyKlaus Tschira Auditorium17 45 18 10Epigenetic Regulation Heterochromatin and Antifungal ResistanceRobin Allshire University of Edinburgh UKNot available on demandKlaus Tschira Auditorium18 10 18 25VIRTUALLinker histone H1 differentially impacts the Polycomb chromatin landscape at genes and telomeric repeats in ArabidopsisFredy Barneche Ecole Normale Sup rieure France remote speaker Klaus Tschira Auditorium18 25 18 40DiMeLo seq mapping protein DNA interactions and DNA modifications on single chromatin fibers using long read sequencingNicolas Altemose Stanford University USAKlaus Tschira Auditorium18 40 19 05The ChAHP complexesMarc B hler Friedrich Miescher Institute for Biomedical Research SwitzerlandNot available on demandKlaus Tschira Auditorium19 05 20 30DinnerEMBL Canteen20 30 22 00Drinks and poster previewATC Foyer and Helix A B Day 2 Tuesday 16th May 2023 Time Berlin Europe SpeakerLocation8 30 9 00Coffee and light refreshmentsAuditorium Foyer9 00 12 30Session 3 Developmental epigeneticsChairs Gary Karpen and Raffaella Santoro9 00 9 25Epigenetic regulation by the MSLs old complex new factsAsifa Akhtar Max Planck Institute of Immunobiology and Epigenetics GermanyNot available on demandKlaus Tschira Auditorium9 25 9 50Mechanism and function of PRC1 and PRC2 in mouse gastrulationYi Zhang Howard Hughes Medical Institute Harvard Medical School and Boston Children s Hospital USANot available on demandKlaus Tschira Auditorium9 50 10 05The Tbx factor Eomes instructs global chromatin dynamics during pluripotency exit to initiate first lineage specificationSebastian Arnold University of Freiburg GermanyKlaus Tschira Auditorium10 05 10 20Signal decoding at the Xist locusEdda Schulz Max Planck Institute for Molecular Genetics GermanyKlaus Tschira Auditorium10 20 11 05Coffee Break Meet the Speakers of Day 2Asifa Akhtar Yi Zhang Nicola Iovino Rong Fan Yehudit Bergman Ibrahim Ciss Efrat ShemaAuditorium Foyer11 05 11 30Epigenetics of early developmentNicola Iovino Max Planck Institute of Immunobiology and Epigenetics GermanyNot available on demandKlaus Tschira Auditorium11 30 11 45Molecular timetable of differentiation in human pluripotent stem cellsMaria Rostovskaya Babraham Institute UKKlaus Tschira Auditorium11 45 12 00Uncovering how the genome directs development mother to daughter cell regulation of chromatin and gene expression in C elegans embryogenesisJulie Ahringer University of Cambridge UKKlaus Tschira Auditorium12 00 12 15Soma to germline small RNA transfer promotes intragenerational survival to environmental stressGermano Cecere Institut Pasteur FranceKlaus Tschira Auditorium12 15 12 30RNA pol I shapes the large scale chromatin architecture in response to nutrients in C elegansDaphne Cabianca Helmholtz Zentrum Munich GermanyNot available on demandKlaus Tschira Auditorium12 30 14 30Lunch Auditorium Foyer13 30 15 30Poster Session I odd numbers Helix A B15 30 18 25Session 4 Single cell genomics and microscopyChairs Asifa Akhtar and Cornelis Murre15 30 15 55Epigenetic programming of allelic extinctionYehudit Bergman Hebrew University of Jerusalem IsraelKlaus Tschira Auditorium15 55 16 10Genome wide profiling of DNA repair detects higher order coordination in single cellsJop Kind Hubrecht Institute The NetherlandsKlaus Tschira Auditorium16 10 16 40Coffee Break Meet the EditorsTiago Faial Linda Koch Sara Osman Sabrya Carim Lavinia Arseni Vitor SousaAuditorium Foyer16 40 17 05Spatial Epigenome Sequencing of Mouse and Human BrainRong Fan Yale University USAKlaus Tschira Auditorium17 05 17 30Single molecule and single cell epigenetics Decoding the epigenome for cancer research and diagnosticsEfrat Shema Weizmann Institute of Science IsraelKlaus Tschira Auditorium17 30 17 55Super resolution imaging of transcription in living cellsIbrahim Ciss Max Planck Institute of Immunobiology and Epigenetics GermanyKlaus Tschira Auditorium17 55 18 10TET activity propagates cellular memory through embryonic dormancyAydan Bulut Karslioglu Max Planck Institute for Molecular Genetics GermanyKlaus Tschira Auditorium18 10 18 25The Drosophila acetyltransferase chameau chm promotes starvation resilience at the expense of a shortened life spanAxel Imhof Ludwig Maximilians University of Munich GermanyKlaus Tschira Auditorium18 25 20 00DinnerEMBL Canteen20 00 22 00Pub quiz with after dinner drinksEMBL Canteen Day 3 Wednesday 17th May 2023 Time Berlin Europe SpeakerLocation8 30 9 00Coffee and light refreshmentsAuditorium Foyer9 00 17 25Session 5 Transcription and chromatin and diseasesMorning Chairs L Stirling Churchman and Robin AllshireAfternoon Chairs Steven Henifkoff and Julie Ahringer9 00 9 25Chromatin regulation in immuno oncologyYang Shi Ludwig Cancer Research UKNot available on demandKlaus Tschira Auditorium9 25 9 40Transcription restart stimulates chromatin reassembly following DNA replicationConstance Alabert University of Dundee UKKlaus Tschira Auditorium9 40 9 55Nucleosomal Asymmetry Regulates Reader Recruitment and Poising at Bivalent DomainsPhilipp Voigt Babraham Institute UKKlaus Tschira Auditorium9 55 10 20Decoding regulatory networks in human development one cell at a timeSarah Teichmann Wellcome Sanger Institute UKKlaus Tschira Auditorium10 20 11 05Coffee Break Meet the Speakers of Day 3Yang Shi Paola Scaffidi L Stirling Churchman Sarah TeichmannAuditorium Foyer11 05 11 30Epigenetic dysregulation and cancer evolutionPaola Scaffidi Francis Crick Institute UKKlaus Tschira Auditorium11 30 11 45Intrinsic transcription factor cooperativity in reconstituted na ve embryonic chromatinPeter B Becker Ludwig Maximilians University of Munich GermanyKlaus Tschira Auditorium11 45 12 00H4K16ac activates the transcription of transposable elements and contributes to their cis regulatory functionPradeepa Madapura Queen Mary University of London UKKlaus Tschira Auditorium12 00 14 00LunchAuditorium Foyer13 00 15 00Poster Session II even numbers Helix A B15 00 15 25RNA Polymerase II pausing temporally coordinates cell cycle progression and erythroid differentiationL Stirling Churchman Harvard Medical School USANot available on demandKlaus Tschira Auditorium15 25 15 40An RNA dependent and phase separated active subnuclear compartment safeguards repressive chromatin domainsRaffaella Santoro University of Zurich SwitzerlandKlaus Tschira Auditorium15 40 15 55Chromatin ubiquitylation in development and diseasePeter Verrijzer Erasmus University Medical Center The NetherlandsKlaus Tschira Auditorium15 55 16 20Epigenetic mechanisms of microglia driven neurodegenerationAnne Sch fer Max Planck Institute for Biology of Ageing Germany remote speaker Klaus Tschira Auditorium16 20 16 35Chem map profiles drug binding to chromatin in cellsZutao Yu University of Cambridge UKKlaus Tschira Auditorium16 35 16 50The Sex specific Factor SOA Establishes X Chromosome Dosage Compensation in Anopheles MosquitosClaudia Keller Valsecchi Institute of Molecular Biology IMB Mainz GermanyKlaus Tschira Auditorium16 50 17 00Poster Prize AnnouncementsKlaus Tschira Auditorium17 00 17 20Coffee BreakAuditorium FoyerFree evening Day 4 Thursday 18th May 2023 Time Berlin Europe SpeakerLocation8 30 9 00Coffee and light refreshmentsAuditorium Foyer9 00 16 40Session 6 Nuclear architectureMorning Chairs Ibrahim Ciss and Paola ScaffidiAfternoon Chairs Nicola Iovino and Yi Zhang9 00 9 25Enhancer promoter contacts depends how you look at itWendy Bickmore The University of Edinburgh UKKlaus Tschira Auditorium9 25 9 40Chromosome scale organization of the regulatory genome in the Drosophila nervous systemMaria Cristina Gambetta University of Lausanne SwitzerlandNot available on demandKlaus Tschira Auditorium9 40 9 55In vitro reconstitution of chromatin domainsMarieke Oudelaar Max Planck Institute for Multidisciplinary Sciences GermanyKlaus Tschira Auditorium9 55 10 20Decoding transcriptional regulationAlexander Stark Research Institute of Molecular Pathology AustriaNot available on demandKlaus Tschira Auditorium10 20 11 05Coffee Break Meet the Speakers of Day 4Wendy Bickmore Alexander Stark Cornelis Murre Haruhiko Koseki Genevieve AlmouzniAuditorium Foyer11 05 11 20Structural basis of H3K36 trimethylation by SETD2 during chromatin transcriptionLucas Farnung Harvard Medical School USAKlaus Tschira Auditorium11 20 11 35Recycling of modified H2A H2B provides short term memory of chromatin statesValentin Flury University of Copenhagen DenmarkKlaus Tschira Auditorium11 35 11 50Poster Prize Short talk 1 Alternative splicing decouples local from global PRC2 activityNiccol Arecco Centre for Genomic Regulation CRG Spain Klaus Tschira Auditorium11 50 12 05Poster Prize Short talk 2 Histone divergence in Trypanosoma brucei results in uniquealterations in nucleosome structureGauri Deak University of Edinburgh UK Klaus Tschira Auditorium12 05 13 35LunchCanteen13 35 14 00Molecular Mechanisms that Instruct Nuclear ShapeCornelis Murre University of California San Diego USANot available on demandKlaus Tschira Auditorium14 00 14 15DNA elements tether Polycomb Repressive Complex 1 to translate histone methylation into chromatin foldingYuri Schwartz Ume University SwedenKlaus Tschira Auditorium14 15 14 30Genome access is transcription factor specific and defined by nucleosome positionRalph Grand Center for Molecular Biology of Heidelberg University ZMBH DKFZ ZMBH Alliance GermanyKlaus Tschira Auditorium14 30 14 55SKP1A links Polycomb repressed genes with proteasomeHaruhiko Koseki RIKEN JapanKlaus Tschira Auditorium14 55 15 25Coffee BreakAuditorium Foyer15 25 15 40Nucleosome sliding in condensed chromatinFelix Mueller Planitz Institute for physiological chemistry TU Dresden GermanyKlaus Tschira Auditorium15 40 15 55Chromosome structure regulated by a transcription dependent RNA polymer gelNick Gilbert The University of Edinburgh UKKlaus Tschira Auditorium15 55 16 40Histones variants and friends a state of play for shaping chromatin and cell fateKeynote speaker Genevi ve Almouzni Institut Curie FranceNot available on demandKlaus Tschira Auditorium16 40 17 00Closing remarksKlaus Tschira Auditorium17 00 18 00Ap ritifATC Foyer18 00 20 30Conference DinnerEMBL Canteen20 30 00 00Conference Party Live DJ and drinksAuditorium Foyer Practical information Registration fees and abstract submission On site registration fees include admission conference materials COVID 19 safety measures meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Virtual registration fees include access to all of the talks live streamed and on demand and the facility to submit questions On site Academia 775On site PhD Student 675On site Industry 975Virtual Academia 200Virtual PhD Student 150Virtual Industry 250 NO visa support letters will be issued until payment of the registration fee is confirmed Accredited journalists may be eligible to register for complimentary press registration Registrants may be required to provide accreditation or equivalent proof of press membership after registration Please contact Charlotte Courtney for more information Please note that we do not offer complimentary registrations for editors of scientific journals Confirmation and payment Registration will be on a first come first served basis Your place can only be confirmed after payment of the registration fee If you are added to our waiting list please consider taking advantage of our offerings to participate virtually On site participants Types of payments accepted are international bank transfers and credit card payments Virtual participants We are only able to accept card payments In exceptional cases we can accept bank transfers Please contact events embl de for details Abstract submission Only participants registering to attend the on site event are eligible to submit an abstract Abstracts will not be accepted from virtual participants After registration you can submit your abstract via a separate link that will be provided in the email confirmation Alternatively you can access the link on the confirmation page directly after registering The same login credentials are used for both processes Please note Abstract body The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised Title The title should not exceed 20 words Only the first word of the title should start with a capital letter and the rest should be lowercase Authors and affiliations Please fill in the author s details as requested in the online form The compulsory fields are First Name Last Name Organisation Name Affiliation or Company Country and Email Kindly mark only one author in the role of First Author and please don t forget to indicate who will be the Presenter Please enter your co authors correctly via the system by adding accounts together with their organisation institute Do not copy paste them into the body of the abstract text as they will not be indexed in the abstract book Presentation types When submitting your abstract you can apply for an oral or poster presentation A selection process will take place with the results announced 2 3 weeks after the abstract submission deadline For detailed instructions on how to submit a conference abstract follow the instructions provided in this video Please check our FAQs pages for further information on how to submit an abstract Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of both registration fee waivers and travel grants These are available for on site participants at EMBL Conferences and EMBO EMBL Symposia and for on site and virtual participants at EMBO Workshops We are currently working on securing funding for all virtual participants and ask that you please apply for financial assistance for both on site and virtual participation Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course or conference Travel grant The travel grant will cover the cost of travel to an on site event airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from within Europe up to 1000 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from outside Europe up to 500 for any participant travelling to an EMBO Workshop up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Workshop up to 700 for any participant working in Croatia Czech Republic Estonia Greece Hungary Italy Lithuania Luxembourg Poland Slovenia and Turkey travelling to an EMBO Workshop Registration fees are only covered for EMBO Workshops The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant EMBO Workshops only For EMBO Workshop participants with children there is the possibility to apply for a childcare grant to offset child care costs incurred by participants or speakers when participating at a conference Eligible costs include fees for a baby sitter or child care facility travel costs for a caregiver or travel costs for taking the child to the meeting etc Please note that priority will be given to early stage researchers A maximum amount of 500 can be awarded per participant applying for an EMBO childcare grant In order to apply for this grant for EMBO Workshops you must be registered by the abstract submission deadline Application On site participants You may apply for financial assistance when submitting your abstract In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Virtual participants If you are attending virtually you can apply for financial assistance in the submission portal by the abstract deadline Read the instructions on how to apply for financial assistance Only submissions for financial assistance will be accepted Presentation abstracts cannot be submitted here and will be declined In your application you will be asked to summarise your current work answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Selection The scientific organisers will select the recipients of all financial assistance during the abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details View our list of external funding opportunities and information on attending a conference as an event reporter For further information about financial assistance please refer to the FAQ page Accommodation and shuttles Accommodation is not included in the conference registration fee As further changes in our events are possible due to COVID 19 you should book flights trains and hotels with flexible options and favourable cancellation conditions The hotels below have rooms on hold for participants until 14th April 2023 in some cases at special rates Please email the hotel directly quoting the booking code CHR23 01 to confirm the exact price of the room Hotel AnlageHotel ibis HeidelbergPremier Inn Heidelberg CityHotel Bayrischer Hof ISG Hotel Staycity Aparthotel HeidelbergB B HotelLeonardo Hotel Heidelberg City CentreSteffi s Hostel HeidelbergExzellenz Hotel Meininger HeidelbergHotel Vier Jahreszeiten HeidelbergHotel Holl nder Hof Hotel Monpti Conference shuttle buses Conference shuttle buses are free of charge for participants and depart from designated bus stops near the hotels to EMBL and back mornings and evenings The bus stops for this conference are Kurf rsten Anlage Opposite Main Train Station Hotel Premier Kurf rsten Anlage 23 Leonardo Hotel Bergheimer Str Neckarmuenzplatz Peterskirche ISG Hotel Staycity Aparthotels Here are the shuttle bus times for EMBL Conference Chromatin and epigenetics View Conference shuttle bus stops and hotels on a larger map Please note that not every bus stop will be used for every event Further details Address EMBL Meyerhofstra e 1 69117 Heidelberg Germany For further information on getting to EMBL Heidelberg visit Public Transportation to the Venue For information about accommodation and local transportation please refer to the FAQ page On site information Catering All meals and coffee breaks are included in the registration fee Our catering staff will prepare a wide variety of vegetarian meals meat and fish dishes soups pasta fresh fruit and vegetables as well as a variety of desserts Please wear your badge at all times when serving yourself No food or drinks are allowed in the auditorium Charging lockers There are lockers available next to the stairs leading down into the Auditorium You will find some of those equipped with sockets to charge your smartphone tablet etc Electricity and charging station In most places the electricity is 220 volts AC 50 cycles An adaptor and a plug that fits the German socket may be needed for your appliances laptop i e American Japanese etc A USB charging station for electronic devices is available at the registration desk EMBL merchandise If you are interested in purchasing an EMBL souvenir products presented in the glass display in the registration area please ask at the registration desk for more information Health and safety notes Please read EMBL s COVID 19 safety policy for on site events Do not smoke in any EMBL building Eating and drinking is prohibited in the Auditorium and all laboratories Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required The first aid room is located next to the ATC Registration Desk room 10 205 Dial the Emergency number 222 from any EMBL internal phone only Where is the accident What happened How many injured Emergency number 06221 387 7821 from mobile phones Please report all accidents to the conference officer at the registration desk In case of fire Press the nearest fire alarm button or the Emergency number 222 from any internal phone A loud fire alarm will go off if an evacuation is required On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting points Do not use the lifts Beyond first aid Please remember to bring your own medication if needed to the conference Note that the next pharmacy is a 4 minute drive from the EMBL but for many medications you will be required to see a doctor to get a prescription Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg In any case the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary Internet Wi Fi is available everywhere on the premises using the EMBL Events network and the event specific password which will be provided on site The eduroam network secure world wide roaming access service developed for the international research and education community is also available Lost and found Lost and Found are kept at the registration desk until the end of the conference Luggage There are lockers available on site to store your luggage which require a 2 EURO coin to operate There is another luggage room on level E0 which is free to use but remains unlocked during the conference Nursing room There is a nursing room available in the ATC Rooftop Lounge on level A29 Photography During the conference an EMBL Photographer may be taking photographs If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Printing We can help printing your boarding passes train ticket Please send it to events embl de and collect your print outs at the registration desk Room for prayer yoga and meditation There is a room for prayer mediation and yoga located on level E0 behind the Auditorium Please be respectful of other participants using the room Sightseeing A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing Travel to and from the venue During the event we provide conference shuttle buses to and from EMBL In addition there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time Information on the conference shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page Useful German expressions HelloHalloGoodbyeAuf WiedersehenGood morningGuten MorgenGood afternoonGuten TagGood eveningGuten AbendGood nightGute NachtI m sorryTut mir leidExcuse me Entschuldigen SieHow are you Wie gehts I m fine thanks And you Mir geht es gut danke und dir Ihnen What is your nameWie heisst du Wie heissen Sie My name isIch heisseDo you speak EnglishSprechen Sie Englisch I don t understandIch verstehe nichtPlease speak more slowlyK nnen Sie bitte langsamer sprechenThank youDankesch nWhere is the toilet Wo ist die Toilette Please call me a taxiBitte rufen Sie mir ein TaxiHow do I get to Wie komme ich zum zur A beer two beers pleaseEin Bier zwei Bier bitteA glass of red white wine pleaseEin Glas Rot Weisswein bitteThe menu pleaseDie Speisekarte bitteIs there a local speciality Gibt es eine Spezialit t aus dieser Gegend I m VegetarianIch bin VegetarierIt was deliciousEs war hervorragendThe bill pleaseDie Rechnung bitteI have a headacheIch habe KopfschmerzenI have a sore throatIch habe HalsschmerzenMy stomach hurtsIch habe MagenschmerzenI m allergic toIch bin allergisch gegenI need a doctor who speaks EnglishGibt es einen Arzt der Englisch spricht Virtual participation What s included Access to all the livestreamed talks Video library of the recorded talks during and after the event Facility to submit questions Please note that only on site participants are able to submit abstracts and participate in the poster sessions Event platform We are using an event platform for this conference More information about the platform will be shared ahead of the conference Guidelines Do not broadcast the conference to unregistered participants You are encouraged to tweet and post about the event Tweet unless the speaker specifically says otherwise but be mindful of unpublished data Please do not capture transmit or redistribute data presented at the meeting Additional information can be found in our Code of Conduct Health and well being It is important to stay healthy and move around especially when you are attending an event virtually We have put together a few coffee break stretches and yoga videos in the conference platform for you to enjoy during the event How to ask questions Please use the Q A function in the event platform If you have any other questions you can go to the Help Desk in the event platform Click on more on the top menu and click Help Desk Time zone The programme is planned based on the Europe Berlin time zone unless otherwise stated Please take your time zone into consideration when planning your attendance Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page COVID 19 related questions COVID 19 information for on site events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Silver sponsor Bronze sponsors Event sponsor Arima Genomics Cell Research New England Biolabs GmbH Media partners Development a The Company of Biologists journal EMBO reports an EMBO Press journal International Union of Biochemistry and Molecular Biology FEBS Letters a FEBS Press journal FEBS Open Bio a FEBS Press journal FEBS Journal a FEBS Press journal Open Biology a Royal Society journal Bio Essays a Wiley Online Library Advanced Biology a Wiley Online Library Nature a Nature Portfolio journal Nature Genetics a Nature Portfolio journal Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information on sponsoring possibilities If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9 Leaderboard 728 90 Pre conference workshop Pre conference workshop For on site participants only This industry webinar will be hosted by our sponsor LUMICKS B V prior to the EMBL Conference Chromatin and Epigenetics on Monday 15 May 2023 13 00 14 00 Participation in this workshop is free of charge for registered on site conference attendees The number of available places is limited first come first served All registered conference attendees will receive an email with a registration link towards the end of April ABSTRACT Single molecule biology democratizing optical tweezers to enable your breakthrough discoveries in chromatin biology and epigenetics Roman Renger Emma Verver Philipp RauchLUMICKS B V Amsterdam The Netherlands The structure regulation maintenance and organization of chromatin is critical to cellular function Errors in the underlying molecular mechanisms play a major role in diseases such as cancer Hence insights into the molecular details are needed to advance our understanding improve biological models and develop novel therapeutics Dynamic single molecule technologies offer an exciting opportunity to meet these challenges and to study protein dynamics function and activity in real time In this workshop we present our efforts for enabling discoveries in the field of chromatin and epigenetics research With the C Trap we provide an easy to use instrument that combines optical tweezers fluorescence microscopy and microfluidics It allows to visualize the interaction and activity of individual protein complexes with and on chromatin in real time assemble chromatin structures in situ and to directly measure the mechanical forces that determine chromatin architecture We will cover several example studies in which our technology biochemistry and data analysis solutions enhanced the understanding of chromatin biology ranging from DNA damage repair to CRISPR Cas based gene editing to nucleosome remodeling and even the mechanical properties of individual chromatin fibers to complete chromosomes...

Asifa Akhtar, Yehudit Bergman, Nicola Iovino, Gary Karpen, Sarah Teichmann

EMBL Conference

EMBL Heidelberg, Virtual

10 May 2023

Developing an improved understanding of the structure and function of the wheat root microbiome

Edit

May 10, 2023 15:302023WebinarVirtual

Description The root microbiome is selected by plants and can benefit crop plants in several ways including improved plant nutritional status as well as protection against biotic and abiotic stresses There are various factors which determine the wheat root microbiome community structure and developing a robust understanding of these is imperative for the development of sustainable agricultural systems This webinar explores the relative importance of factors such as fertilisation regime land management and plant genotype in shaping the structure and function of the wheat root microbiome and how this knowledge can be taken forward to develop microbiome facilitated agriculture...

Tim Mauchline

Virtual

10 May 2023

Data protection and privacy preservation in software development

Edit

May 10, 2023 15:002023WebinarVirtual

Description When writing software to process health genetic or other sensitive data in High Performance Computing HPC clusters software developers and researchers must consider the requirements of the General Data Protection Regulation including the principle of privacy by design and the duties of data protection In this webinar we will highlight the risks of working with sensitive data on an HPC cluster and what are common software vulnerabilities We will discuss general best practices in software development and provide guidelines on how to handle data in applications We will also raise awareness of outside factors that affect data security and briefly mention important generic organisational measures that should be in place About the speaker Sarah Peter studied Bioinformatics and worked for a few years as a researcher and data manager at the Max Planck Institute Now she works at the Luxembourg Centre for Systems Biomedicine UNILU as an Infrastructure Engineer in the R3 and IT Infrastructure team She is also the liaison for the HPC team Since GDPR has come into effect she spends some of her time doing risk analysis for the institute s IT infrastructure and the HPC cluster...

Virtual

9 May - 12 May 2023

The organism and its environment

Edit

May 09, 2023 00:002023ConferenceEMBL Heidelberg, Virtual

Description OverviewSpeakersProgrammePractical informationSponsorsAboutMedia kit Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Symposium overview We are at the dawn of a new era of biology where we will start to understand how organisms function together and react or adapt to changes at different molecular levels This includes the multitude of stressors that organisms are exposed to from malnutrition and adverse climate events to many other biological chemical and physical insults Progress in biological analyses at both a single scale and across scales have allowed us to further understand organisms in the context of dynamic environments These can be environments which are changed by disease commensal cohabitation or competition as well as abiotic factors With the molecular understanding we already have at the cellular and organismal levels and new tools and quantitative approaches this symposium will address how genotype and the environment bring about phenotypes at the population level Topics Biodiversity Marine symbiosis Terrestrial Symbiosis Theory of organismal interactions Enviromental adptation in model organisims Paleogenomics What past participants say about the symposium An excellent meeting covering important topics for future research with outstanding speakers and excellent enthusiastic students Isabel Gordo Instituto Gulbenkian de Ci ncia Portugal I really enjoyed the quality and diversity of the talks all related but different Enriching and awesomely organized conference Julie Zaworski New England Biolabs USA One of the most enriching conferences in the recent past Great venue great food great support team and outstanding speakers and presentations Kudos to the AV team for the glitch free remote presentations A great platform for young researchers and emerging scientists Anupam Sengupta University of Luxembourg Please see EMBL s COVID 19 safety recommendations if attending the on site event Speakers Keynote speaker Richard Durbin University of Cambridge UK Speakers Yasmine Belkaid National Institutes of Health USA Virtual speaker Silvia Bulgheresi University of Vienna Austria Maria Dzunkova University of Valencia Spain Kate Farquharson University of Sydney Australia Aissam Ikmi EMBL Heidelberg Germany Martin Kaltenpoth Max Planck Institute for Chemical Ecology Germany Jos Maria Montoya Teran CNRS France Raquel Peixoto King Abdullah University Saudi Arabia Virtual speaker Emma Rocke University of Cape Town South Africa Wenying Shou University College London United Kingdom Raffaele Siano IFREMER France Sk li Sk lason H lar University and the Icelandic Museum of Natural History Iceland Ricard Sol Catalan Institute for research and Advanced Studies Spain Flora Vincent EMBL Heidelberg Germany Detlef Weigel Max Planck Institute for Biology T bingen Germany Phillip Wilcox University of Otago New Zealand Anna Zaidman Remy INSA Lyon France Virtual speaker Scientific organisers Detlev Arendt EMBL Heidelberg Germany Edith Heard EMBL Heidelberg Germany Maria Leptin European Research Council Belgium Fiona Watt EMBO Germany Detlef Weigel Max Planck Institute for Biology T bingen Germany Conference organiser Maria Mercedes Bacadare Goitia EMBL Heidelberg Germany Programme Got something to say Tweet it EESOrganism For registered participants recorded talks will be accessible on demand for 2 weeks after the end of the event unless indicated otherwise Day 1 Tuesday 9 May 2023 Time Europe Berlin Speaker14 00 15 00Registration and light refreshments15 00 15 15Opening remarks15 15 18 30Session 1 BiodiversityChair Tobias Gerber EMBL Heidelberg Germany15 15 15 45In what way does the organism environment association drive the development and evolution of biological diversity Sk li Sk lason H lar University College Iceland15 45 16 00A Diatoms tale from the sea to lab and back Antonella Ruggiero EMBL Stazione Zoologica A Dohrn Germany16 00 16 15Evolution of canalization lessons from a classic case of resource polymorphismKalina Kapralova University of Iceland Iceland16 15 17 00Coffee break17 00 17 30Australian genomes saving us and saving themKate Farquharson The University of Sydney Australia17 30 17 45Functional analysis of dna methylation in the marbled crayfish as a model to study rapid adaptation and invasivenessJaime Diaz Larrosa German Cancer Research Center DKFZ Germany17 45 18 00Targeted volume Correlative Light and Electron Microscopy of an environmental marine microorganismKarel Mocaer EMBL Heidelberg GermanyNot available on demand18 00 18 30Plant ParanoiaDetlef Weigel Max Planck Institute for Biology T bingen Germany18 30 19 30Dinner in Canteen19 30 20 30Drinks in ATC Rooftop lounge Day 2 Wednesday 10 May 2023 Time Europe Berlin Speaker09 30 12 00Session 2 Marine symbiosisChair Antonella Ruggiero EMBL Heidelberg Germany Stazione Zoologica Anton Dohrn Italy09 30 10 00Microbial communities driving nutrient and carbon cycling in the Southern Benguela upwelling regionEmma Rocke University of Cape Town South Africa10 00 10 15Interactions between marine picocyanobacteria and particulate chitinGiovanna Capovilla Massachusetts Institute of Technology MIT United States of America10 15 10 30The genetic mechanisms underlying the transition to piscivoryMarina de la C mara University of Iceland Iceland10 30 11 00Coffee break11 00 11 30Synthase selected single cell genomics for discovering symbiotic microbes providing chemical defense for soft bodied marine animalsMaria Dzunkova Univeristy of Valencia Spain11 30 11 45Bacterial physiology in an environmental ContextEinat Segev Weizmann Institute of Science Israel11 45 12 00Nitric oxide signaling controls collective contractions in a colonial choanoflagellateJosean Reyes Rivera University of California Berkeley Howard Hughes Medical Institute United States of AmericaNot available on demand12 00 13 00Lunch13 00 17 00Session 2 Marine symbiosis cont Chair Detleft Weigel Max Planck Institute for Biology T bingen Germany13 00 13 30Viral impacts in the marine world from single cells to planktonic ecosystemsFlora Vincent EMBL Heidelberg Germany13 30 13 45Unravelling the role of venom in predator prey interactions using natural populations and transgenic approaches in Nematostella vectensisJoachim Surm The Hebrew University of Jerusalem Israel13 45 14 00Determining hotspots of cellular adaptation in the marine ragworm Platynereis dumeriliiTobias Gerber EMBL Heidelberg Germany14 00 14 30Coffee break14 30 15 00Cell biology of bacteria that live on the surface of animalsSilvia Bulgheresi University of Vienna Austria15 00 15 30Restoration and rehabilitation of coral microbiomesRaquel Peixoto King Abdullah University of Science and Technology Saudi Arabia Remote speaker 15 30 16 00Flash talks 2 minutes 1 slide per talk 36 James Cleland 37 Bechara Saade 38 Markus Ulrich 39 Bettina Welz and 40 Frederic Zimmer16 00 17 00Poster Session17 00Free evening Day 3 Thursday 11 May 2023 Time Europe Berlin Speaker10 00 13 00Session 3 Terrestrial SymbiosisChair Einat Segev Weizmann Institute of Science Israel10 00 10 30When the environment is another organism deciphering the insect bacteria molecular dialogue in a nutritional mutualistic endosymbiosisAnna Zaidman Remy BF2i Lab UMR INRAE INSA Lyon France Remote speaker Not available on demand10 30 10 45Caenorhabditis elegans susceptibility to virus infection is modulated by its naturally associated bacteriaRuben Gonzalez French National Center for Scientific Research CNRS France10 45 11 00Indicators and partner specificity in plant fungal interactionsLeho Tedersoo University of Tartu Estonia11 00 11 45Coffee break11 45 12 15Outsourcing immunity Symbiont mediated defense of immature life stages in beetlesMartin Kaltenpoth MPI Chemical Ecology Jena GermanyNot available on demand12 15 12 30When noise is regulation and regulation is noise how bacteria adapt their phenotypes in an uncertain environmentErik van Nimwegen University of Basel Switzerland12 30 13 00Microbiome Control of Host ImmunityYasmine Belkaid NIH National Institute of Allergy and Infectious Diseases USA Remote speaker 13 00 14 00Lunch14 00 18 00Session 4 TheoryChair Raphael Aguillon Bar Ilan University Israel 14 00 14 30Quantitative biology of microbial phenotypes in changing environmentsWenying Shou University College London UK14 30 14 45Selective capture at phenotypic boundaries enhances population evolvability in a changing environmentBhaskar Kumawat University of Michigan United States of America Remote speaker 14 45 15 00Zooming in and back out again Biochemical reflections of intergenerational environmental history across the life course with examples in ADHDSu Chu Brigham and Women s Hospital and Harvard Medical School United States of AmericaNot available on demand15 00 15 30Terraforming ecosystems from synthetic biology to community ecologyRicard Sol Catalan Institute for research and Advanced Studies Spain15 30 16 15Coffee break16 15 16 45When less isn t more the value of indigenous knowledge in understanding the relationship between the organism and its environmentPhillip Wilcox University of Otago New Zeland16 45 17 15Ecology and evolution of host microbiome networksJose Maria Montoya Teran CNRS France17 15 18 00Keynote Exploring ancient ecosystems using environmental DNARichard Durbin University of Cambridge UK18 00 19 00Dinner in Canteen19 00 21 00Drinks in ATC Rooftop lounge Day 4 Friday 12 May 2023 Time Europe Berlin Speaker09 00 10 45Session 5 Environmental adaptation in model organismsChair Giovanna Capovilla Massachusetts Institute of Technology MIT United States of America09 00 09 30Linking animal behavior to life history transition in CnidariaAissam Ikmi EMBL Heidelberg Germany09 30 09 45Clockwise adaptation CLOCK s role in nematostella s circadian response to environmental cuesRaphael Aguillon Bar Ilan University Israel09 45 10 00Short heat stress has a long term effect on mesenchymal stem cells transcriptome and their differentiation propertiesIvana Ribarski Chorev The Hebrew University Israel10 00 10 30Coffee break10 30 10 45Exposure to elevated temperature fatally disrupts nuclear divisions in the early Drosophila embryo Girish Kale Centre for Organismal Studies Heidelberg University Germany10 45 11 00Session 6 PaleogenomicsChair Giovanna Capovilla Massachusetts Institute of Technology MIT United States of America10 45 11 15Marine dinoflagellate phenology variations in a changing environmentRaffaele Siano IFREMER France11 15 11 30Closing Remarks11 30 11 45Packed Lunch and departure Practical information Registration fees and abstract submission On site registration fees include admission conference materials COVID 19 safety measures meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Virtual registration fees include access to all of the talks livestreamed and on demand and facility to submit questions On site Academia 700On site PhD Student 600On site Industry 900Virtual Academia 200Virtual PhD Student 150Virtual Industry 250 A letter to support your visa application will be issued on request once payment of the registration fee is confirmed We recommend that you book your visa appointment as soon as possible to avoid any delay with your visa application Accredited journalists may be eligible to register for complimentary press registration Registrants may be required to provide accreditation or equivalent proof of press membership after registration Please contact Maria Bacadare for more information Please note that we do not offer complimentary registrations for editors of scientific journals Confirmation and payment Registration will be on a first come first served basis Your place can only be confirmed after payment of the registration fee If you are added to our waiting list please consider taking advantage of our offerings to participate virtually On site participants Types of payments accepted are international bank transfers and credit card payments Virtual participants We are only able to accept card payments In exceptional cases we can accept bank transfers Please contact events embl de for details Abstract submission Only participants registering to attend the on site event are eligible to submit an abstract Abstracts will not be accepted from virtual participants After registration you can submit your abstract via a separate link that will be provided in the email confirmation Alternatively you can access the link on the confirmation page directly after registering The same login credentials are used for both processes Please note Abstract body The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised Title The title should not exceed 20 words Only the first word of the title should start with a capital letter and the rest should be lowercase Authors and affiliations Please fill in the author s details as requested in the online form The compulsory fields are First Name Last Name Organisation Name Affiliation or Company Country and Email Kindly mark only one author in the role of First Author and please don t forget to indicate who will be the Presenter Please enter your co authors correctly via the system by adding accounts together with their organisation institute Do not copy paste them into the body of the abstract text as they will not be indexed in the abstract book Presentation types When submitting your abstract you can apply for an oral or poster presentation A selection process will take place with the results announced 2 3 weeks after the abstract submission deadline For detailed instructions on how to submit a conference abstract follow the instructions provided in this video Please check our FAQs pages for further information on how to submit an abstract Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of both registration fee waivers and travel grants These are available for on site participants at EMBL Conferences and EMBO EMBL Symposia and for on site and virtual participants at EMBO Workshops We are currently working on securing funding for all virtual participants and ask that you please apply for financial assistance for both on site and virtual participation Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course or conference Travel grant The travel grant will cover the cost of travel to an on site event airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from within Europe up to 1000 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from outside Europe up to 500 for any participant travelling to an EMBO Workshop up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Workshop up to 700 for any participant working in Croatia Czech Republic Estonia Greece Hungary Italy Lithuania Luxembourg Poland Slovenia and Turkey travelling to an EMBO Workshop Registration fees are only covered for EMBO Workshops The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Application On site participants You may apply for financial assistance when submitting your abstract In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Virtual participants If you are attending virtually you can apply for financial assistance in the submission portal by the abstract deadline Read the instructions on how to apply for financial assistance Only submissions for financial assistance will be accepted Presentation abstracts cannot be submitted here and will be declined In your application you will be asked to summarise your current work answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Selection The scientific organisers will select the recipients of all financial assistance during the abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details View our list of external funding opportunities and information on attending a conference as an event reporter For further information about financial assistance please refer to the FAQ page Accommodation and shuttles Accommodation is not included in the conference registration fee As further changes in our events are possible due to COVID 19 you should book flights trains and hotels with flexible options and favourable cancellation conditions The hotels below have rooms on hold for participants until Tuesday 11 April 2023 in some cases at special rates Please email the hotel directly quoting the booking code EES23 03 to confirm the exact price of the room Exzellenz HotelMeininger HeidelbergStaycity Aparthotel HeidelbergHotel ibis HeidelbergPremier Inn Heidelberg CityHotel Vier Jahreszeiten HeidelbergLeonardo Hotel Heidelberg City Centre Conference shuttle buses Conference shuttle buses are free of charge for participants and depart from designated bus stops near the hotels to EMBL and back mornings and evenings Conference shuttle bus schedule The bus stops for this conference are Hotel Staycity Speyerer Str 7 Kurf rsten Anlage Opposite Main Train Station Premier Inn Kurf rsten Anlage 23 Leonardo Hotel Heidelberg City Center Bergheimer Str 63 Neckarm nzplatz Heidelberg Tourist Information Peterskirche Bus stop Bahnhofstr 9 near Penny supermarket View Conference shuttle bus stops and hotels in a larger map Please note that not every bus stop will be used for every event Further details Address EMBL Meyerhofstra e 1 69117 Heidelberg Germany For further information on getting to EMBL Heidelberg visit Public Transportation to the Venue For information about accommodation and local transportation please refer to the FAQ page On site information Catering All meals and coffee breaks are included in the registration fee Our catering staff will prepare a wide variety of vegetarian meals meat and fish dishes soups pasta fresh fruit and vegetables as well as a variety of desserts Please wear your badge at all times when serving yourself No food or drinks are allowed in the auditorium Charging lockers There are lockers available next to the stairs leading down into the Auditorium You will find some of those equipped with sockets to charge your smartphone tablet etc Electricity and charging station In most places the electricity is 220 volts AC 50 cycles An adaptor and a plug that fits the German socket may be needed for your appliances laptop i e American Japanese etc A USB charging station for electronic devices is available at the registration desk EMBL merchandise If you are interested in purchasing an EMBL souvenir products presented in the glass display in the registration area please ask at the registration desk for more information Health and safety notes Please read EMBL s COVID 19 safety policy for on site events Do not smoke in any EMBL building Eating and drinking is prohibited in the Auditorium and all laboratories Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required The first aid room is located next to the ATC Registration Desk room 10 205 Dial the Emergency number 222 from any EMBL internal phone only Where is the accident What happened How many injured Emergency number 06221 387 7821 from mobile phones Please report all accidents to the conference officer at the registration desk In case of fire Press the nearest fire alarm button or the Emergency number 222 from any internal phone A loud fire alarm will go off if an evacuation is required On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting points Do not use the lifts Beyond first aid Please remember to bring your own medication if needed to the conference Note that the next pharmacy is a 4 minute drive from the EMBL but for many medications you will be required to see a doctor to get a prescription Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg In any case the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary Internet Wi Fi is available everywhere on the premises using the EMBL Events network and the event specific password which will be provided on site The eduroam network secure world wide roaming access service developed for the international research and education community is also available Lost and found Lost and Found are kept at the registration desk until the end of the conference Luggage There are lockers available on site to store your luggage which require a 2 EURO coin to operate There is another luggage room on level E0 which is free to use but remains unlocked during the conference Nursing room There is a nursing room available in the ATC Rooftop Lounge on level A29 Photography During the conference an EMBL Photographer may be taking photographs If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Printing We can help printing your boarding passes train ticket Please send it to events embl de and collect your print outs at the registration desk Room for prayer yoga and meditation There is a room for prayer mediation and yoga located on level E0 behind the Auditorium Please be respectful of other participants using the room Sightseeing A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing Travel to and from the venue During the event we provide conference shuttle buses to and from EMBL In addition there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time Information on the conference shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page Useful German expressions HelloHalloGoodbyeAuf WiedersehenGood morningGuten MorgenGood afternoonGuten TagGood eveningGuten AbendGood nightGute NachtI m sorryTut mir leidExcuse me Entschuldigen SieHow are you Wie gehts I m fine thanks And you Mir geht es gut danke und dir Ihnen What is your nameWie heisst du Wie heissen Sie My name isIch heisseDo you speak EnglishSprechen Sie Englisch I don t understandIch verstehe nichtPlease speak more slowlyK nnen Sie bitte langsamer sprechenThank youDankesch nWhere is the toilet Wo ist die Toilette Please call me a taxiBitte rufen Sie mir ein TaxiHow do I get to Wie komme ich zum zur A beer two beers pleaseEin Bier zwei Bier bitteA glass of red white wine pleaseEin Glas Rot Weisswein bitteThe menu pleaseDie Speisekarte bitteIs there a local speciality Gibt es eine Spezialit t aus dieser Gegend I m VegetarianIch bin VegetarierIt was deliciousEs war hervorragendThe bill pleaseDie Rechnung bitteI have a headacheIch habe KopfschmerzenI have a sore throatIch habe HalsschmerzenMy stomach hurtsIch habe MagenschmerzenI m allergic toIch bin allergisch gegenI need a doctor who speaks EnglishGibt es einen Arzt der Englisch spricht Virtual participation What s included Access to all the livestreamed talks Video library of the recorded talks during and after the event Facility to submit questions Please note that only on site participants are able to submit abstracts and participate in the poster sessions Event platform We are using an event platform for this conference More information about the platform will be shared ahead of the conference Guidelines Do not broadcast the conference to unregistered participants You are encouraged to tweet and post about the event Tweet unless the speaker specifically says otherwise but be mindful of unpublished data Please do not capture transmit or redistribute data presented at the meeting Additional information can be found in our Code of Conduct Health and well being It is important to stay healthy and move around especially when you are attending an event virtually We have put together a few coffee break stretches and yoga videos in the conference platform for you to enjoy during the event How to ask questions Please use the Q A function in the event platform If you have any other questions you can go to the Help Desk in the event platform Click on more on the top menu and click Help Desk Time zone The programme is planned based on the Europe Berlin time zone unless otherwise stated Please take your time zone into consideration when planning your attendance Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page COVID 19 related questions COVID 19 information for on site events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Media partners Disease Models Mechanisms The Company of Biologists Journal EMBO Journal an EMBO Press journal International Union of Biochemistry and Molecular Biology Open Biology a Royal Society journal Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de About EMBO EMBL Symposia promote scientific communication and collaboration in the European research area They provide scientists with a platform to discuss and exchange ideas on forward looking topics and new developments in the life sciences Topics emphasise upcoming developments and the interdisciplinary nature of related fields Jointly funded and organised by EMBO and EMBL and complementary to their respective courses workshops and conference programmes the symposia promote scientific communication and collaboration All symposia are held in the EMBL Advanced Training Centre ATC in Heidelberg Germany or virtually Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 Leaderboard 728 90...

Detlev Arendt, Edith Heard, Maria Leptin, Fiona Watt, Detlef Weigel

EMBO | EMBL Symposium

EMBL Heidelberg, Virtual

8 May - 12 May 2023

Data visualisation for biology

Edit

May 08, 2023 00:002023CourseEMBL-EBI

Description This course will give insights into and practical experience in data visualisation for exploring complex and multi dimensional biological data Biological and life sciences data often consists of multiple dimensions a combination of numerical values ordered data categories and time series To make sense of this data simple plots like scatterplots barcharts and boxplots are often not enough Still visualisation is critical in gaining deep insight into the data This is why many custom visualisations originated in the biological field In this course we will dive into the topic of visualisation of complex biological data and how it can be used to gain insight into and get a feel for a dataset so that targeted analyses can be defined It will be delivered through a mixture of lectures and workshop sessions and will provide hands on experience in developing visualisations The course will focus on working with omics e g genomics transcriptomics data rather than e g imaging data Additional information The course fee is inclusive of four nights accommodation and catering including dinner We plan to deliver this course in an in person manner onsite at our training suite at EMBL EBI Hinxton Hybrid options are not currently available Please be aware that we are continually evaluating the ongoing pandemic situation and as such may need to change the format of courses at short notice Your safety is paramount to us you can read our COVID guidance policy for more information All information is correct at time of publishing Monday 8 May will be a bank holiday in the UK to mark the Coronation of King Charles III The course will take place as outlined in the programme including sessions as planned on Monday 8 May Should you be selected as a participant please take extra care planning your travel to the course as public transport may be affected by the Coronation Saturday 6 May and bank holiday Please also note that there are delays in the issuing of visas from the UK Government We encourage you to check if you need a visa and apply in plenty of time before travelling Current waiting times are more than six weeks For more information please visit the UK Government website...

Jane Reynolds

EMBL-EBI

7 May - 12 May 2023

Advanced fluorescence imaging techniques

Edit

May 07, 2023 00:002023CourseEMBL Heidelberg

Description OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview Please see EMBL s COVID 19 safety policy for testing and other requirements to attend this on site course Course overview This practical course will cover advanced light microscopy techniques and participants will learn how to derive qualitative and quantitative insights on molecular mechanisms in cells and developing organisms Invited guest researchers together with microscopy experts from EMBL will foster an intense information flow with a balance of lectures and practical workshops The focus of the course will be on the use of fluorescence microscopy to obtain information about localisation and functions of proteins and other bio molecules at different spatial scales Audience This course is directed towards researchers in the life sciences with access to light microscopy equipment who have an immediate need to apply the techniques they will learn to solve biological problems at the cellular and molecular level in vivo As the course will be primarily focused on the advanced techniques we expect participants to have basic knowledge of light microscopy Modules resources The topics will include fluorescence microscopy techniques such as fast time lapse microscopy of living cells spinning disk and point scanning confocal microscopy light sheet microscopy of cleared samples photo manipulation as a tool multicolour single molecule localization microscopy SMLM with spectral demixing expansion microscopy FRET based techniques For demanding applications we will cover the aspects of image processing and analysis and the possibilities of microscope automation The modules will cover all necessary knowledge and demonstrate tools to conduct similar pipelines at your home lab enabling you to answer emerging biological questions Learning outcomes Get an overview of advanced fluorescence imaging techniques Obtain hands on experience setting up and running advanced experiments on modern fluorescence microscopes Discuss the possibilities and drawbacks of experiment planning and data interpretation with experts in the field This course is kindly supported by the EMBL Advanced Light Microscopy Facility This course is organised in cooperation with Evident What past participants say I highly recommend this course if you are looking to take your fluorescence microscopy experiments to the next level Josefina Marin Rojas Universidad de Chile Chile Speakers Speakers trainers and staff Alexander Aulehla EMBL Heidelberg Germany Ipek Altinoglu Abbelight France Joana Delgado Martins University of Zurich Switzerland Ulrike Endesfelder University of Bonn Germany Manuel Alexander Peter Gunkel EMBL Heidelberg Germany Aliaksandr Halavatyi EMBL Heidleberg Germany Mark Hink University of Amsterdam The Netherlands Ines H fer Evident Germany Robert Kasper Evident Germany Debora Keller Olivier Abbelight France Simone K hler EMBL Heidelberg Germany Marko Lampe EMBL Heidelberg Germany Stefan Marawske Evident Germany Felix Mikus EMBL Heidelberg Germany Pedro Pereira ITQB NOVA Portugal Marianna Poli EMBL Heidelberg Germany Irina Rakotoson PhaseView France Anjalie Schlaeppi EPFL Switzerland Stefan Terjung EMBL Heidelberg Germany Urs Ziegler University of Zurich Switzerland Scientific organisers Joana Delgado Martins University of Zurich Switzerland Manuel Alexander Peter Gunkel EMBL Heidelberg Germany Aliaksandr Halavatyi EMBL Heidleberg Germany Debora Keller Olivier Abbelight France Stefan Marawske Evident Germany Irina Rakotoson PhaseView France Course Organisers Lea Hohmann Course and Conference Manager EMBL Heidelberg Germany Swetlana Krez Training Lab Technician EMBL Heidelberg Germany Programme Day 1 7 May 2023 Time Europe Berlin SpeakerLocation15 30 16 00RegistrationISG Hotel Seminar Room Berlin16 00 16 30WelcomeISG Hotel Seminar Room Berlin16 30 19 30Flash talks by participantsISG Hotel Seminar Room Berlin19 30 21 00DinnerISG Hotel Day 2 8 May 2023 Time Europe Berlin SpeakerLocation08 40Bus from ISG Hotel to EMBLHotel entrance08 55 09 00Safety briefing by Swetlana Krez EMBL HeidelbergCourtyard Room A B09 00 10 00Lecture Q A Concepts in Light microscopyUrs Ziegler University of Zurich SwitzerlandCourtyard Room A B10 00 11 00Lecture Q A DIY super resolution Expanding biology above diffractionPedro Matos Pereira ITQB PortugalCourtyard Room A B11 00 11 10Coffee BreakCourtyard Room A B11 10 11 30Lecture How Euro BioImaging can support your research with access to the best imaging Marianna Poli EMBL Heidelberg GermanyCourtyard Room A B11 30 12 30Lecture Q A Light sheet microscopyRobert Kasper Evident GermanyCourtyard Room A B12 30 13 30LunchEMBL Canteen13 30 16 00Hands on practical 1 Live cell imagingJoana Delgado University of Zurich SwitzerlandUrs Ziegler University of Zurich Switzerland Groups 1 2 3D imaging of model organisms with CLSMStefan Terjung EMBL Heidelberg GermanyStefan Marawske Evident Groups 3 4 Microscopy rooms 116 11716 00 16 15Coffee breakCourtyard Room A B16 15 18 45Hands on practical 2 3D imaging of model organisms with CLSMStefan Terjung EMBL Heidelberg GermanyStefan Marawske Evident Groups 1 2 DeconvolutionUrs Ziegler University of Zurich Switzerland Groups 3 4 Microscopy rooms 116 117Computer training lab18 45 19 45DinnerEMBL Canteen19 45Bus to HotelATC Entrance Day 3 9 May 2023 Time Europe Berlin SpeakerLocation08 40Bus from ISG Hotel to EMBLHotel entrance09 00 10 00Lecture Q A Adaptive Feedback MicroscopyAliaksandr Halavatyi EMBL Heidelberg GermanyCourtyard Room A B10 00 11 00Lecture Q A Visualizing chromosomes during meiosis Simone K hler EMBL Heidelberg GermanyCourtyard Room A B11 00 11 30Coffee breakCourtyard Room A B11 30 12 30Practical Setting and debugging adaptive feedback microscopy pipelinesManuel Gunkel EMBL Heidelberg GermanyComputer training lab12 30 13 30LunchEMBL Canteen13 30 16 00Hands on practical 3 Applying adaptive feedback microscopy for high throughput photoactivation of specific cell phenotypesAliaksandr Halavatyi EMBL Heidelberg GermanyManuel Gunkel EMBL Heidelberg Germany Group 1 TBCGroup 2Deconvolution Urs Ziegler University of Zurich Switzerland Groups 3 4 Microscopy rooms 116 11716 00 16 15Coffee breakCourtyard Room A B16 15 18 45Hands on practical 4 Applying adaptive feedback microscopy for high throughput photoactivation of specific cell phenotypes Aliaksandr Halavatyi EMBL Heidelberg Germany Manuel Gunkel EMBL Heidelberg Germany Groups 3 TBC Group 4 Deconvolution Urs Ziegler University of Zurich Switzerland Groups 1 2 Computer training labMicroscopy rooms 116 11718 45 20 00Pizza dinner and informal discussion20 00Bus to HotelATC entrance Day 4 10 May 2023 Time Europe Berlin SpeakerLocation08 40Bus from ISG Hotel to EMBLHotel entrance09 00 09 45Lecture Q A Introduction to SMLM from concepts to samples Debora Keller Olivier Abbelight FranceCourtyard Room A B09 45 10 45Lecture Q A Measuring interactions and biosensors using FRETMark Hink University of Amsterdam The NetherlandsCourtyard Room A B10 45 11 15Coffee break11 15 12 30Practical Preparation of expansion microscopy samplesPedro Matos Pereira ITQB PortugalTraining Lab12 30 13 30LunchEMBL Canteen13 30 16 00Hands on practical 5 Multicolor Single molecule Localization Microscopy with Spectral DemixingDebora Keller Olivier Abbelight France Group 1 Ultra thin light sheet microscope with automated multi scale imaging capabilitiesRobert Kasper Evident Germany Group 2 FRETMark Hink University of Amsterdam The Netherlands Group 3 Imaging expanded samplesPedro Matos Pereira ITQB Portugal Group 4 Microscopy rooms 116 11716 00 16 15Coffee breakCourtyard Room A B16 15 18 30Hands on practical 6 Ultra thin light sheet microscope with automated multi scale imaging capabilitiesRobert Kasper Evident Germany Group 1 Multicolor Single molecule Localization Microscopy with Spectral DemixingDebora Keller Olivier Abbelight France Group 2 Imaging expanded samplesPedro Matos Pereira ITQB Portugal Group 3 FRETMark Hink University of Amsterdam The Netherlands Group 4 Microscopy rooms 116 11718 30Bus to dinner downtownATC entrance Day 5 11 May 2023 Time Europe Berlin SpeakerLocation09 00 10 00Lecture Q A Visualizing chromosomes during meiosisSimone K hler EMBL Heidelberg Germany Q A Courtyard Room A B10 00 11 00Lecture Q A We can start testing next month practical considerations for spatial transcriptomics and multiplexing Anjalie Schlaeppi EPFLCourtyard Room A B11 00 11 30Coffee breakCourtyard Room A B11 30 12 30Lecture Q A Visualizing cellular life From single cell imaging to in vivo single molecule biophysics biochemistry and structural micro biologyUlrike Endesfelder University of Bonn GermanyCourtyard Room A B12 30 13 30LunchEMBL Canteen13 30 16 00Hands on practical 7 FRETMark Hink University of Amsterdam The Netherlands Group 1 Imaging expanded samplesPedro Matos Pereira ITQB Portugal Group 2 Applying adaptive feedback microscopy for high throughput photoactivation of specific cell phenotypesAliaksandr Halavatyi EMBL Heidelberg GermanyManuel Gunkel EMBL Heidelberg Germany Group 3 Multicolor Single molecule Localization Microscopy with Spectral DemixingDebora Keller Olivier Abbelight France Group 4 Microscopy rooms 116 11716 00 16 15Coffee breakCourtyard Room A B16 15 18 45Hands on practical 8 Imaging expanded samplesPedro Matos Pereira ITQB Portugal Group 1 FRETMark Hink University of Amsterdam The Netherlands Group 2 Multicolor Single molecule Localization Microscopy with Spectral DemixingDebora Keller Olivier Abbelight France Group 3 Applying adaptive feedback microscopy for high throughput photoactivation of specific cell phenotypesAliaksandr Halavatyi EMBL Heidelberg GermanyManuel Gunkel EMBL Heidelberg Germany Group 4 Microscopy rooms 116 11718 45 19 45DinnerEMBL Canteen19 45 20 45Informal Q A discussion and drinksCourtyard Room A B20 45Departure to HotelATC entrance Day 6 12 May 2023 Time Europe Berlin SpeakerLocation09 00 10 30Practical FRET data analysisMark Hink University of Amsterdam The NetherlandsComputer training lab10 30 11 00Coffee breakoutside Computer training lab11 00 12 30Practical SMLM data analysisMarko Lampe EMBL Heidelberg GermanyComputer training lab12 30 13 30LunchEMBL Canteen13 30 14 45Preparation of student presentationsComputer training lab14 45 16 15Student presentationsComputer training lab16 15 16 40Wrap up of course and departure16 40Bus to Heidelberg main stationATC entrance Practical information Registration fees and motivation letter The course is limited to 16 participants For selection purposes please note that your application will not be considered without a letter of motivation Registration Registration fees include admission course materials COVID 19 safety measures meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Academia 550PhD Student 550Industry 1100 A letter to support your visa application will be issued on request once payment of the registration fee is confirmed We recommend that you book your visa appointment as soon as possible to avoid any delay with your visa application Confirmation and payment The registration fee should be paid only after acceptance to the course The results will be announced approximately 2 3 weeks after the application deadline Motivation letter submission After you have logged in and successfully registered you will receive an email asking you to submit your motivation letter Click on the link provided and enter your motivation letter in the text box provided Alternatively you can submit your motivation letter by clicking on the link on the confirmation page directly after registering Instructions Include your relevant skills experience and qualifications showing why you would be suitable for the course Explain why you would like to attend including what you can contribute and how you think you will benefit from the course Please note The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised For detailed instructions please watch our video on how to submit a course motivation letter Further details For further information about registration and motivation letter submission please refer to the FAQ page Accommodation and shuttles Hotel Single rooms have been reserved for 5 nights 7 12 May 2023 at the ISG Hotel After the selection process selected participants should contact the hotel directly to make a booking booking code MIC23 02 We recommend that all course participants stay at the ISG Hotel which is the dedicated hotel for the course Local transport Shuttle buses will go from the ISG Hotel to EMBL and back mornings and evenings Please see the bus schedule here Further details Address EMBL Heidelberg Meyerhofstra e 1 69117 Heidelberg GermanyFor further information on getting to EMBL Heidelberg visit our Travel Information page For enquiries about accommodation and local transportation please refer to the FAQ page Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of both registration fee waivers and travel grants Availability is limited to participants attending on site EMBL Courses and virtual or on site EMBO Practical Courses in Heidelberg and will be indicated during the motivation letter submission process Your place in the course is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course Travel grant The travel grant will cover the cost of travel airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Course within Europe up to 1000 for participants travelling to an EMBL Course from outside Europe up to 500 for any participant travelling to an EMBO Practical Course up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Practical Course up to 700 for any participant working in Croatia Czech Republic Estonia Greece Hungary Italy Lithuania Luxembourg Poland Slovenia and Turkey travelling to an EMBO Practical Course Registration fees are only covered for EMBO Practical Courses The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Boehringer Ingelheim Fonds travel grant Applies to selected courses only Availability will be indicated during the motivation letter submission process This grant covers costs related to your attendance at the course registration travel and accommodation costs The grant is restricted to PhD students and postdocs who conduct basic biomedical research Whether you are eligible to apply for a travel grant depends on when you received your university entrance qualification e g Abitur A Levels High School Diploma Final State Examination for PhD and MD students as well as graduates the university entrance qualification must not have been obtained more than 11 years ago at the time of the envisaged course for postdocs the university entrance qualification must not have been obtained more than 13 years ago at the time of the envisaged course Application You may apply for financial assistance when submitting your motivation letter for courses In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application For the Boehringer Ingelheim Fonds Travel Grant there is a pre application question during the motivation letter submission process and if selected you will be requested to complete a standard form and documentation consisting of your travel expense estimation Selection The scientific organisers will select the recipients of all financial assistance during the motivation letter selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the course Selection is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details See our list of external funding opportunities and for further information about financial assistance please refer to the FAQ page Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page COVID 19 related questions COVID 19 information for on site events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other events or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9...

Aliaksandr Halavatyi, Stefan Marawske, Rainer Pepperkok, Stefan Terjung

EMBL Course

EMBL Heidelberg

3 May 2023

Historical perspectives on plant science databases

Edit

May 03, 2023 15:302023WebinarVirtual

Description This webinar will discuss the history of database development in the plant sciences with a focus on European efforts to build international cross institutional genebank databases Although accounts of these often focus on the need for well curated and cross linked databases to adequately serve research communities it is equally important to consider the political and economic motivations behind database development Exploring the history of data management in the plant sciences can potentially help researchers recognise and navigate contemporary challenges...

Helen Anne Curry

Virtual

26 April 2023

Applications and impacts of the BrAPI project on plant breeding

Edit

April 26, 2023 15:302023WebinarVirtual

Description Modern genomic breeding methods rely heavily on very large amounts of phenotypic and genotypic data presenting new challenges in effective data management and integration The datasets are often large and complex and the data is often stored on multiple systems sometimes separated by country and organisation As the common analyses methods increasingly require aggregation of datasets from diverse sources data exchange between disparate systems becomes a challenge This webinar will be an introduction to The Breeding API BrAPI Project The BrAPI Project began in 2014 when a small group of plant breeding and technology experts came together to try to standardise their data Since then BrAPI has become internationally accepted as one of the primary data exchange standards in the plant breeding domain This webinar will give an overview of what BrAPI is how it works what it is capable of and the impact the project has had so far on the community...

Peter Selby

Virtual

25 April - 28 April 2023

Brain genome: regulation, evolution, and function

Edit

April 25, 2023 00:002023ConferenceEMBL Heidelberg, Virtual

Description OverviewSpeakersProgrammePractical informationSponsorsAboutMedia kit Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Please see EMBL s COVID 19 safety recommendations if attending the on site event Symposium overview This symposium explores the many ways by which the genome is regulated in the brain in order to support neural function and plasticity The extraordinary complexity of the brain places unique demands on the genome How are several hundreds of different neural types specified by the same genetic instructions Does the genome provide information that guides their connectivity How is neural activity regulated by and how does it affect genome output We will explore these fundamental questions from the standpoint of transcriptional regulation and chromatin based processes including but not limited to histone marks and variants chromatin topology and folding coding and noncoding RNAs transposable elements and DNA modifications The conference aims to bring together neuroscientists and experts in genome regulation It will cover a broad range of experimental approaches and model systems from biochemistry to single cell genomics from worms to human organoids Overall the conference will address the impact of genome regulation on unique features of the brain its excitable nature exquisite response to the environment and parallel processing capacity with the longer term vision of understanding how defective genome regulation can give rise to brain disease Session topics Interplay between gene regulation and neuronal activity Genomic regulation of brain plasticity and behaviour Chromatin variations in the brain From one genome to many neurons neurodevelopment and neural diversity Speakers Angel Barco Instituto de Neurociencias UMH CSIC Spain Brenda Bloodgood University of California San Diego USA Roberto Bonasio University of Pennsylvania USA remotely Claude Desplan New York University USA Yukiko Gotoh University of Tokyo Japan Magdalena G tz Ludwig Maximilian University of Munich and Helmholtz Zentrum M nchen Germany Johannes Gr ff EPFL Switzerland Elizabeth Heller University of Pennsylvania USA Johan Jakobsson Lund University Sweden Daniel Kronauer The Rockefeller University USA Ryan Lister The University of Western Australia Australia Stavros Lomvardas Columbia University USA Ana Martin Villalba German Cancer Research Center Germany Ian Maze Icahn School of Medicine at Mount Sinai USA Lindy McBride Princeton University USA Kyung Min Noh EMBL Heidelberg Germany Coleen T Murphy Princeton University USA Gaia Novarino Institute of Science and Technology Austria Austria Sergiu Pasca Stanford University USA Ana Pombo Max Delbr ck Center for Molecular Medicine Germany Anne Sch fer Max Planck Institute for Biology of Ageing Germany Alex Schier University of Basel Switzerland Pelin Cayirlioglu Volkan Duke University USA Scientific organisers Roberto Bonasio University of Pennsylvania USA remotely Matthieu Boulard EMBL Rome Italy Magdalena G tz Ludwig Maximilian University of Munich and Helmholtz Zentrum M nchen Germany Kyung Min Noh EMBL Heidelberg Germany Conference organiser Iva Gavran EMBL Heidelberg Germany Programme Got something to say Tweet it EESBrainGenome For registered participants recorded talks will be accessible on demand for 2 weeks after the end of the event unless indicated otherwise Programme is subject to change Day 1 Tuesday 25 April 2023 Time Europe Berlin Speaker12 00 13 30Registration and refreshments light lunch 13 30 13 45Opening remarks13 45 18 00Session 1 From one genome to many neurons neurodevelopment and neural diversityChair Gaia Novarino Institute of Science and Technology Austria Austria13 45 14 15Chromatin level regulation of neural stem cell fate during mouse neocortical developmentYukiko Gotoh The University of Tokyo JapanNot available on demand14 15 14 45Epigenetic etiology of intellectual disabilityAngel Barco Instituto de Neurociencias UMH CSIC SpainNot available on demand14 45 15 00Joint epigenome profiling reveals cell type specific gene regulatory programs in human cortical organoidsBoyan Bonev Helmholtz Zentrum M nchen Germany15 00 15 15Deep learning from scMultiomes suggests conserved gene regulatory codes for mammalian and avian brain cell typesNikolai Hecker VIB KU Leuven Center for Brain Disease Research Belgium15 15 15 45Transposable elements and the evolution of the human brainJohan Jakobsson Lund University Sweden15 45 16 15Coffee Break and Meet the speakers with Yukiko Gotoh Angel Barco Johan Jakobsson16 15 16 45From Stem Cells to Organoids to Assembloids and Toward Building Human Circuits in Living SystemsSergiu Pasca Stanford University USA16 45 17 00Mapping Neuronal Networks in Cerebral Organoids with Single cell Transcriptional ResolutionRamsey Najm Institute of Molecular Biotechnology Austria17 00 17 15Primate expressed EPIREGULIN promotes basal progenitor proliferation in the developing neocortexMareike Albert Technical University Dresden GermanyNot available on demand17 15 17 45Reconstructing cellular biographiesAlex Schier Biozentrum University of Basel Switzerland17 45 18 00Development and evolution of the mammalian cerebellum at single cell resolutionMari Sepp Heidelberg University GermanyNot available on demand18 00 19 00Poster previews and Meet the speakers with Sergiu Pasca and Alex Schier19 00 20 30Canteen dinner20 30 22 00Networking in the ATC Rooftop lounge Day 2 Wednesday 26 April 2023 Time Europe Berlin Speaker09 15 12 15Session 2 Genomic regulation of brain plasticity and behaviorChair Boyan Bonev Helmholtz Zentrum M nchen Germany09 15 09 45Autism associated chromatin dysregulation hinders synaptic plasticityGaia Novarino Institute of Science and Technology Austria Austria09 45 10 00Sites of transcription initiation drive mRNA isoform selection in the brainValerie Hilgers Max Planck Institute of Immunobiology and Epigenetics Germany10 00 10 15Adaptation phenotypic plasticity and the brain in a changing worldCelia Schunter University of Hong Kong Hong Kong10 15 10 45Coffee Break and Meet the speakers with Gaia Novarino10 45 11 15Protein monoaminylation in brain novel mechanisms of neural development plasticity and diseaseIan Maze Howard Hughes Medical Institute Icahn School of Medicine at Mount Sinai United States of America11 15 11 30Manipulation of neural stem cell fates through activation of global protein translation rates using a novel CRISPR approachStefan Stricker Ludwig Maximilians University of Munich Helmholtz Zentrum Germany11 30 11 45The regulatory determinants of modern human brain development and evolutionAlessandro Vitriolo Human Technopole Italy11 45 12 15Epigenetic editing for the study of addictionElizabeth Heller University of Pennsylvania USA12 15 13 45Lunch and Meet the speakers with Ian Maze and Elizabeth Heller13 45 17 00Session 2 Genomic regulation of brain plasticity and behavior continued Chair Ryan Lister The University of Western Australia Australia13 45 14 15Pheromone communication in antsDaniel Kronauer The Rockefeller University USANot available on demand14 15 14 30Convergent and complementary selection shaped the evolution of social behavior in beesSarah Kocher Princeton University United States of America14 30 14 45L1 retrotransposons drive human neuronal transcriptome complexity and functional diversificationDiahann Atacho Lund University Sweden14 45 15 15EGL 30 GNAQ activation rejuvenates age related cognitive decline in worms and mammals Coleen T Murphy Princeton University USA15 15 15 45Coffee Break and Meet the speakers with Daniel Kronauer Coleen Murphy and Carolyn McBride15 45 16 15Socially induced brain plasticity and behavioral reprogramming in antsRoberto Bonasio University of Pennsylvania USA remote talk 16 15 16 30Nup153 regulates activity dependent gene expression in neuronsAbhinav Soni German Center for Neurodegenrative Diseases Dresden GermanyNot available on demand16 30 17 00A map of neuronal diversity on mosquito antennae reveals rampant co expression and co option of olfactory receptorsCarolyn McBride Princeton University USA17 00 17 30Flash talksBonefas Katherine 53 Porrua Odil 65 Kentro James 71 Martelli Carlotta 81 Rowland Megan 93 Soliman Azza 99 Winter Julia 111 Yip Kwok Yui Reymond Tony 11317 30 19 00Poster Session 1 odd with beer and light refreshments19 15Free evening bus downtown Day 3 Thursday 27 April 2023 Time Europe Berlin Speaker09 30 12 45Session 3 Interplay between gene regulation and neuronal activity Chair Lindy McBride Princeton University USA09 30 09 45Histone H3K79 methylation demarcates an epigenetic barrier of progenitor differentiation and neuronal maturation in cerebral cortex and hippocampus developmentTanja Vogel University of Freiburg Germany 09 45 10 00Condensins restrict retrotransposable element expression and activity in neural stem cells to promote Drosophila brain developmentMichelle Longworth Cleveland Clinic Lerner Research Institute United States of America10 00 10 30Novel mechanisms of endogenous and induced neurogenesisMagdalena G tz Ludwig Maximilian University of Munich and Helmholtz Zentrum M nchen Germany10 30 11 00Coffee Break and Meet the speakers with Magdalena G tz11 00 11 30Transcriptional regulation of inhibitory synapses impacts place field coding and stabilityBrenda Bloodgood University of California San Diego USA11 30 11 45Spatial enhancer activation determines inhibitory neuron identityElena Dvoretskova Max Planck Institute for Biological Intelligence GermanyNot available on demand11 45 12 15Chromatin plasticity predetermines neuronal eligibility for memory trace allocationJohannes Gr ff EPFL Switzerland12 15 12 45Evolution of neural diversityClaude Desplan New York University USA12 45 14 15Lunch and Meet the speakers14 15 17 15Session 4 Chromatin variations in the brainChair Stefan Stricker Ludwig Maximilians University of Munich Helmholtz Zentrum Germany14 15 14 45The effect of social experience on gene expression circuit function and behaviorsPelin Volkan Duke University USA14 45 15 00linc mipep and linc wrb encode micropeptides that regulate chromatin accessibility in vertebrate specific neural cellsValerie Tornini Yale University United States of America15 00 15 15Regulatory genomics of primate astrocyte evolutionAleksandra Pekowska Nencki Institute of Experimental Biology Polish Academy of Sciences Poland15 15 15 45Olfactory receptor mRNAs as selfish lnRNAs that promote transcriptional singularityStavros Lomvardas Columbia University USA15 45 16 15Coffee Break and Meet the speakers with Pelin Volkan Stavros Lomvardas and Ana Martin Villalba16 15 16 45The molecular secrets of stemness in the adult healthy and injured brain Ana Martin Villalba German Cancer Research Center DKFZ Germany16 45 17 00HP1 Deficiency Results in De Repression of Endogenous Retroviruses and Induction of Neurodegeneration via Complement Andrew Newman Charit Universit tsmedizin Berlin Germany17 00 17 15Epigenetically distinct synaptic architecture in clonal compartments in the teleostean dorsal palliumYasuko Isoe Harvard University United States of America17 15 17 45Flash talksBurgos Ruiz Ana Mar a 54 Castilla Vallmanya Laura 56 Gracia Diaz Carolina 66 Horvath Vivien 68 Jacobs Jelle 70 Kitanishi Yuki 72 Krick Keegan 74 Mall Moritz 80 Schofield Mia 96 Villamor Paya Marina 108 Wiseglass Gil 11217 45 19 15Poster Session 2 even with beer and snacks19 15 21 00Conference dinner21 00 23 00Live music and drinks Day 4 Friday 28 April 2023 Time Europe Berlin Speaker09 15 12 30Session 4 continued Chromatin variations in the brainChair Elizabeth Heller University of Pennsylvania USA09 15 09 45Specialization of 3D genome structure in different brain cells and cell stateAna Pombo Max Delbr ck Center for Molecular Medicine Germany09 45 10 00L1 RNAs regulate cortical development by tuning PRC2 activityDamiano Mangoni Istituto Italiano di Tecnologia Italy10 00 10 30The operational principles of neuron microglia circuitsAnne Schaefer Max Planck Institute for Biology of Ageing Germany10 30 11 00Coffee Break and Meet the speakers with Ana Pombo Anne Schaefer Ryan Lister and Kyung Min Noh11 00 11 30Human prefrontal cortex gene regulatory dynamics from gestation to adulthood at single cell resolutionRyan Lister The University of Western Australia Australia11 30 11 45SATB2 organizes the 3D genome architecture of cognition in cortical neuronsGalina Apostolova Medical University of Innsbruck Austria11 45 12 00A PRC2 network controls neural progenitor death division and differentiationJamy Peng St Jude Children s Research Hospital United States of America12 00 12 30Functional single cell genomics of transcription factors and chromatin regulators associated with neurodevelopmental disordersKyung Min Noh EMBL Heidelberg Germany12 30 12 45Closing Remarks and Poster prize12 45 13 15Packed lunch and departure Practical information Registration fees and abstract submission On site registration fees include admission conference materials COVID 19 safety measures meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Virtual registration fees include access to all of the talks livestreamed and on demand and facility to submit questions On site Academia 700On site PhD Student 600 On site Industry 900Virtual Academia 200Virtual PhD Student 150Virtual Industry 250 NO visa support letters will be issued until payment of the registration fee is confirmed Accredited journalists may be eligible to register for complimentary press registration Registrants may be required to provide accreditation or equivalent proof of press membership after registration Please contact Iva Gavran for more information Please note that we do not offer complimentary registrations for editors of scientific journals Confirmation and payment Registration will be on a first come first served basis Your place can only be confirmed after payment of the registration fee If you are added to our waiting list please consider taking advantage of our offerings to participate virtually On site participants Types of payments accepted are international bank transfers and credit card payments Virtual participants We are only able to accept card payments In exceptional cases we can accept bank transfers Please contact events embl de for details Abstract submission Only participants registering to attend the on site event are eligible to submit an abstract Abstracts will not be accepted from virtual participants After registration you can submit your abstract via a separate link that will be provided in the email confirmation Alternatively you can access the link on the confirmation page directly after registering The same login credentials are used for both processes Please note Abstract body The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised Title The title should not exceed 20 words Only the first word of the title should start with a capital letter and the rest should be lowercase Authors and affiliations Please fill in the author s details as requested in the online form The compulsory fields are First Name Last Name Organisation Name Affiliation or Company Country and Email Kindly mark only one author in the role of First Author and please don t forget to indicate who will be the Presenter Please enter your co authors correctly via the system by adding accounts together with their organisation institute Do not copy paste them into the body of the abstract text as they will not be indexed in the abstract book Presentation types When submitting your abstract you can apply for an oral or poster presentation A selection process will take place with the results announced 2 3 weeks after the abstract submission deadline For detailed instructions on how to submit a conference abstract follow the instructions provided in this video Please check our FAQs pages for further information on how to submit an abstract Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO as well as other partner institutions in the form of both registration fee waivers and travel grants These are available for on site participants at EMBL Conferences and EMBO EMBL Symposia and for on site and virtual participants at EMBO Workshops We are currently working on securing funding for all virtual participants and ask that you please apply for financial assistance for both on site and virtual participation Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course or conference CPP and EMBO travel grants The travel grant will cover the cost of travel to an on site event airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from within Europe up to 1000 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from outside Europe up to 500 for any participant travelling to an EMBO Workshop up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Workshop up to 700 for any participant working in Croatia Czech Republic Estonia Greece Hungary Italy Lithuania Luxembourg Poland Slovenia and Turkey travelling to an EMBO Workshop Registration fees are only covered for EMBO Workshops Boehringer Ingelheim Stiftung travel grants up to 800 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from within Europe as well as the cost of registration up to 1 800 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from outside Europe as well as the cost of registration The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Application On site participants You may apply for financial assistance when submitting your abstract In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Virtual participants If you are attending virtually you can apply for financial assistance in the submission portal by the abstract deadline Read the instructions on how to apply for financial assistance Only submissions for financial assistance will be accepted Presentation abstracts cannot be submitted here and will be declined In your application you will be asked to summarise your current work answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Selection The scientific organisers will select the recipients of all financial assistance during the abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details View our list of external funding opportunities and information on attending a conference as an event reporter For further information about financial assistance please refer to the FAQ page Accommodation and shuttles Accommodation is not included in the conference registration fee As further changes in our events are possible due to COVID 19 you should book flights trains and hotels with flexible options and favourable cancellation conditions The hotels below have rooms on hold for participants until 27 March 2023 in some cases at special rates Please email the hotel directly quoting the booking code EES23 02 to confirm the exact price of the room Hotel AnlageHotel ibis HeidelbergPremier Inn Heidelberg CityHotel Bayrischer Hof ISG Hotel Staycity Aparthotel HeidelbergB B HotelLeonardo Hotel Heidelberg City CentreSteffi s Hostel HeidelbergExzellenz HotelMeininger HeidelbergHotel Vier Jahreszeiten HeidelbergHotel Holl nder Hof Hotel Monpti Conference shuttle buses Conference shuttle buses are free of charge for participants and depart from designated bus stops near the hotels to EMBL and back mornings and evenings Conference shuttle bus schedule The bus stops for this conference are Hotel Staycity Speyerer Str 7 Kurf rsten Anlage Opposite Main Train Station Hotel Premier Inn Kurf rsten Anlage 23 Leonardo Hotel Heidelberg City Center Bergheimer Str 63 Neckarmuenzplatz Heidelberg Tourist Information Peterskirche View Conference shuttle bus stops and hotels in a larger map Please note that not every bus stop will be used for every event Further details Address EMBL Meyerhofstra e 1 69117 Heidelberg Germany For further information on getting to EMBL Heidelberg visit Public Transportation to the Venue For information about accommodation and local transportation please refer to the FAQ page On site information Catering All meals and coffee breaks are included in the registration fee Our catering staff will prepare a wide variety of vegetarian meals meat and fish dishes soups pasta fresh fruit and vegetables as well as a variety of desserts Please wear your badge at all times when serving yourself No food or drinks are allowed in the auditorium Charging lockers There are lockers available next to the stairs leading down into the Auditorium You will find some of those equipped with sockets to charge your smartphone tablet etc Electricity and charging station In most places the electricity is 220 volts AC 50 cycles An adaptor and a plug that fits the German socket may be needed for your appliances laptop i e American Japanese etc A USB charging station for electronic devices is available at the registration desk EMBL merchandise If you are interested in purchasing an EMBL souvenir products presented in the glass display in the registration area please ask at the registration desk for more information Health and safety notes Please read EMBL s COVID 19 safety policy for on site events Do not smoke in any EMBL building Eating and drinking is prohibited in the Auditorium and all laboratories Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required The first aid room is located next to the ATC Registration Desk room 10 205 Dial the Emergency number 222 from any EMBL internal phone only Where is the accident What happened How many injured Emergency number 06221 387 7821 from mobile phones Please report all accidents to the conference officer at the registration desk In case of fire Press the nearest fire alarm button or the Emergency number 222 from any internal phone A loud fire alarm will go off if an evacuation is required On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting points Do not use the lifts Beyond first aid Please remember to bring your own medication if needed to the conference Note that the next pharmacy is a 4 minute drive from the EMBL but for many medications you will be required to see a doctor to get a prescription Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg In any case the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary Internet Wi Fi is available everywhere on the premises using the EMBL Events network and the event specific password which will be provided on site The eduroam network secure world wide roaming access service developed for the international research and education community is also available Lost and found Lost and Found are kept at the registration desk until the end of the conference Luggage There are lockers available on site to store your luggage which require a 2 EURO coin to operate There is another luggage room on level E0 which is free to use but remains unlocked during the conference Nursing room There is a nursing room available in the ATC Rooftop Lounge on level A29 Photography During the conference an EMBL Photographer may be taking photographs If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Printing We can help printing your boarding passes train ticket Please send it to events embl de and collect your print outs at the registration desk Room for prayer yoga and meditation There is a room for prayer mediation and yoga located on level E0 behind the Auditorium Please be respectful of other participants using the room Sightseeing A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing Travel to and from the venue During the event we provide conference shuttle buses to and from EMBL In addition there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time Information on the conference shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page Useful German expressions HelloHalloGoodbyeAuf WiedersehenGood morningGuten MorgenGood afternoonGuten TagGood eveningGuten AbendGood nightGute NachtI m sorryTut mir leidExcuse me Entschuldigen SieHow are you Wie gehts I m fine thanks And you Mir geht es gut danke und dir Ihnen What is your nameWie heisst du Wie heissen Sie My name isIch heisseDo you speak EnglishSprechen Sie Englisch I don t understandIch verstehe nichtPlease speak more slowlyK nnen Sie bitte langsamer sprechenThank youDankesch nWhere is the toilet Wo ist die Toilette Please call me a taxiBitte rufen Sie mir ein TaxiHow do I get to Wie komme ich zum zur A beer two beers pleaseEin Bier zwei Bier bitteA glass of red white wine pleaseEin Glas Rot Weisswein bitteThe menu pleaseDie Speisekarte bitteIs there a local speciality Gibt es eine Spezialit t aus dieser Gegend I m VegetarianIch bin VegetarierIt was deliciousEs war hervorragendThe bill pleaseDie Rechnung bitteI have a headacheIch habe KopfschmerzenI have a sore throatIch habe HalsschmerzenMy stomach hurtsIch habe MagenschmerzenI m allergic toIch bin allergisch gegenI need a doctor who speaks EnglishGibt es einen Arzt der Englisch spricht Virtual Participation What s included Access to all the livestreamed talks Video library of the recorded talks during and after the event Facility to submit questions Please note that only on site participants are able to submit abstracts and participate in the poster sessions Event platform We are using an event platform for this conference More information about the platform will be shared ahead of the conference Guidelines Do not broadcast the conference to unregistered participants You are encouraged to tweet and post about the event Tweet unless the speaker specifically says otherwise but be mindful of unpublished data Please do not capture transmit or redistribute data presented at the meeting Additional information can be found in our Code of Conduct Health and well being It is important to stay healthy and move around especially when you are attending an event virtually We have put together a few coffee break stretches and yoga videos in the conference platform for you to enjoy during the event How to ask questions Please use the Q A function in the event platform If you have any other questions you can go to the Help Desk in the event platform Click on more on the top menu and click Help Desk Time zone The programme is planned based on the Europe Berlin time zone unless otherwise stated Please take your time zone into consideration when planning your attendance Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page COVID 19 related questions COVID 19 information for on site events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Bronze sponsor Event sponsorsAAAS Science Advances Active Motif BGI Genomics Cell ResearchEvent supporters Media partners EMBO reports an EMBO Press journal FEBS Journal a FEBS Press journal FEBS Letters a FEBS Press journal International Union of Biochemistry and Molecular Biology Bio Essays a Wiley Online Library Advanced Biology a Wiley Online Library Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de About EMBO EMBL Symposia promote scientific communication and collaboration in the European research area They provide scientists with a platform to discuss and exchange ideas on forward looking topics and new developments in the life sciences Topics emphasise upcoming developments and the interdisciplinary nature of related fields Jointly funded and organised by EMBO and EMBL and complementary to their respective courses workshops and conference programmes the symposia promote scientific communication and collaboration All symposia are held in the EMBL Advanced Training Centre ATC in Heidelberg Germany or virtually Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9 Leaderboard 728 90...

Roberto Bonasio, Matthieu Boulard, Magdalena Götz, Kyung-Min Noh

EMBO | EMBL Symposium

EMBL Heidelberg, Virtual

25 April - 27 April 2023

Bioinformatics resources for protein biology

Edit

April 25, 2023 00:002023CourseVirtual

Description Are you aware of the wide range of protein data resources that can easily be accessed and explored to enhance your research Do you want to know more about the sequence of your protein and its functions Wondered whether a structure of your protein exists and how to explore it Want to know more about the potential complexes and reaction pathways your protein of interest is involved in giving you a better overview of its biological context This short virtual course will introduce you to data resources and tools developed by EMBL EBI that can help you in your protein studies During the first three days you will learn about how to browse retrieve and use EMBL EBI protein data in theory Those who are interested in learning more about programmatic access to EMBL EBI protein resources can attend an optional section on this topic on 25 April 2023 For an introduction to the concept of web services and how you can use them to access the tools and data available at EMBL EBI please watch our webinar You will then be provided exercises for each resource you will work through on your own in the following week with remote trainer support available if needed We will meet again on 3 May 2023 to discuss issues that occurred while working through the material in more detail Additional information Please note that we will operate this course virtually Hybrid options are not currently available We reserve the right to change the format of this course or cancel it due to the ongoing coronavirus pandemic Virtual course Participants will learn via a mix of pre recorded lectures live presentations and trainer Q A sessions Practical experience will be developed through group activities and trainer led computational exercises Live sessions will be delivered using Zoom with additional support and asynchronous communication via Slack Pre recorded material may be provided before the course starts that participants will need to watch read or work through to gain the most out of the actual training event In the week before the course there may be a brief induction session Participants will need to be available between the hours of 09 45 16 30 GMT each day of the course Trainers will be available to assist answer questions and provide further explanations during these times...

Juanita Riveros

Virtual

19 April 2023

Kew tree of life project: discovering the phylogeny of all flowering plants

Edit

April 19, 2023 15:302023WebinarVirtual

Description High throughput sequencing has transformed approaches to phylogenetic analysis allowing the construction of trees based on multiple loci and consideration of incongruence between nuclear and plastid data This webinar will highlight how the Hyb Seq method enriches whole genome sequence data for target genes and can be used on preserved specimens enabling a cost effective and practicable strategy for the rigorous investigation of plant evolutionary relationships over a broad taxonomic scope The Royal Botanic Gardens Kew has already generated a phylogeny covering over half of all flowering plant genera and aims to complete the tree at the generic level by 2025...

Bill Baker

Virtual

18 April 2023

From transcriptomics to mechanistic models of signalling

Edit

April 18, 2023 00:002023CourseVirtual

Description Event registration is now full Cellular signalling networks are the communication pathways that govern the behaviour of cells They allow cells to receive and process external signals such as growth factors and hormones and respond appropriately by activating specific gene expression programs or inducing cellular behaviours like proliferation migration and differentiation Disruptions in these signalling networks can lead to various diseases including cancer metabolic disorders and immune disorders Understanding the regulatory mechanisms of signalling networks is critical to developing effective therapies for these diseases One approach to discover signalling network alterations from omics data is through the use of upstream regulatory pathway analysis which aims to identify the transcription factors and upstream signalling regulators that control the expression of downstream genes This can be achieved through the joint analysis of omics data and the signalling network structure using methods such as CARNIVAL By using powerful algorithms and general purpose integer optimization solvers CARNIVAL explores the vast space of potential signalling alterations to identify a parsimonious signalling network that explains the measurements In this course participants will learn how to process differential gene expression data to estimate transcription factor activities with DecoupleR obtain and process prior knowledge networks with OmniPath and pypath and use CARNIVAL to infer signalling networks...

Daniel V. Thomas Lopez

Virtual

17 April - 24 April 2023

Microbial metagenomics: a 360º approach

Edit

April 17, 2023 00:002023CourseEMBL Heidelberg

Description OverviewSpeakersPreliminary programmePractical informationSponsorsMedia kit Overview Course overview The course focuses on the highly interdisciplinary topic of metagenomics During the course participants will receive an overview of state of the art genomic technologies and bioinformatic tools A balanced approach of lectures and practical sessions will provide a general background and the latest advancements in the field as well as its relationship with other disciplines The course will start with training the participants about experimental design and the preparation of their own metagenomic libraries with soil or their environmental samples The metagenomic DNA will be sequenced onsite using third generation sequencing technologies and subsequent data analysis Thus the students have a unique opportunity to work on the complete workflow from sample preparation to data analysis This updated course version will also address cutting edge single cell microbial genomics during practical Bioinformatics analysis is a key part of the course where students will learn how to process data from raw sequences to the application of algorithms for analysing metagenomic datasets Trainers will provide short lectures with follow up hands on exercises in order to have the participants learning and assessing their knowledge Audience This course is aimed at advanced PhD students and post doctoral researchers who are doing or planning to start research in the field of metagenomics Modules resources Experimental design Extraction of metagenomic DNA Construction of metagenomic libraries Single cell microbial genomics 3rd generation sequencing Nanopore Bioinformatic analysis of metagenomic data data standards and submission processing of raw data assembly functional annotation overview of databases retrieval and analysis tools Learning outcomes Construct your own metagenomic library Analyse and organise your data Interpret results explore different databases use different retrieval and analysis tools Sequence analysis What past participants say about the course This course gave me the opportunity to learn from my coursemates and understand the software used in metagenomics The speakers were friendly and are always ready to answer our research questions and provide us with valuable advice and comments Lee Hwei Huih The University of Hong Kong Please see EMBL s COVID 19 safety policy for testing and other requirements to attend this on site course Speakers Speakers trainers and staff Vladimir Benes EMBL Heidelberg Germany Josefa Ant n Botella University of Alicante Spain Giuseppe D Auria FISABIO Sequencing and Bioinformatics Spain Jos Eduardo Gonz lez Pastor Center of Astrobiology CSIC INTA Spain Daniel Huson University of T bingen Germany Kostas Konstantinidis Georgia Institute of Technology USA Eugeni Belda IRD UMMISCO INSERM NutriOmique France Arantxa L pez L pez Hospital Can Misses Spain Gabrielle Potocki Veronese French National Institute for Agricultural Research INRA France Mariana Reyes Prieto FISABIO Sequencing and Bioinformatics Spain Lorna Richardson EMBL EBI UK Kristian Vlahovicek University of Zagreb Croatia Tobias Wenzel Pontificia Universidad Cat lica de Chile Chile Georg Zeller EMBL Heidelberg Germany Daphne Welter EMBL Heidelberg Germany Laura Villacorta EMBL Heidelberg Germany Luis Miguel Rodriguez R University of Innsbruck Austria Dienty Hendrina Maria Johanna Hazenbrink EMBL Heidelberg Germany Lukas Mathur EMBL Heidelberg Germany Jean Karim H rich EMBL Heidelberg Germany Yi Sun EMBL Heidelberg Germany Scientific organisers Vladimir Benes EMBL Heidelberg Germany Giuseppe D Auria FISABIO Sequencing and Bioinformatics Spain Jos Eduardo Gonz lez Pastor Center of Astrobiology CSIC INTA Spain Elisabeth Zielonka EMBL Heideilberg Germany Course organisers Diah Yulianti EMBL Heidelberg Germany Swetlana Krez EMBL Heidelberg Germany Preliminary programme Got something to say Tweet it EMBOMetaG Some pre course work such as watching pre recordings protocol reading and computational exercises with estimated time 0 10 hours will be required and will be shared in advance of the course Some speakers may need to join virtually to give their lecture or Q A and the programme is subject to change Day 0 Onboarding day Monday 3 April 2023 TimeSpeakerLocation16 00 17 00 Overview of pre course work introduction to course content on EMBL eCampus Virtual Day 1 Monday 17 April 2023 Time Europe Berlin Speaker Location 09 00 09 15 Welcome and EMBL overviewElisabeth Zielonka EMBL Heidelberg Germany Courtyard Room A B09 15 09 30 Introduction to Training Lab and House notesEMBL Heidelberg Germany Courtyard Room A B09 30 09 45Welcome and IntroductionsJos Eduardo Gonz lez Pastor Center of Astrobiology CSIC INTA Spain Courtyard Room A B09 45 10 45 Flash talks participantsElisabeth Zielonka EMBL Heidelberg Germany Courtyard Room A B10 45 11 00 BREAK11 00 12 00 Metagenomics Concepts historical milestones and next advanceJos Eduardo Gonz lez Pastor Center of Astrobiology CSIC INTA Spain Courtyard Room A B12 00 13 00 LUNCH EMBL Canteen13 00 14 00 Metagenomics library preparation for NGSVladimir Benes EMBL Heidelberg GermanyCourtyard Room A B14 00 15 00 Group ActivityChallenges and Expectations Courtyard Room A B15 00 16 00 The impact of Metagenomics on genes and genomes discoveryGabrielle Potock i Veronese INRA LISBP FranceCourtyard Room A B16 00 16 30 BREAK 16 30 17 30 What brings a metagenomic approach in cardiometabolic and nutrition related disorders Eugeni Belda IRD UMMISCO INSERM NutriOmique France Courtyard Room A B17 30 20 00 Poster Session 1 and Pizza dinnerHelix A and Rooftop Lounge Day 2 Tuesday 18 April 2023 Time Europe Berlin Speaker Location 09 00 09 15 Quick overview of the dayJos Eduardo Gonz lez Pastor Center of Astrobiology CSIC INTA Spain Courtyard Room A B09 15 10 30 PRACTICAL 1 Extraction of metagenomic DNA in groups from soil samplesJos Eduardo Gonz lez Pastor Center of Astrobiology CSIC INTA SpainArantxa Lopez Hospital Can Misses Spain Training Lab A B10 30 11 00 BREAK 11 00 12 30 PRACTICAL 2Quality control of DNA samples and Nanopore 16S PCR set upDaphne Welter EMBL Heidelberg Germany Laura Villacorta EMBL Heidelberg GermanyTraining Lab A B12 30 13 30 LUNCHEMBL Canteen13 30 14 30Discussion of metagenomic DNA Extraction ResultsJos Eduardo Gonz lez Pastor Center of Astrobiology CSIC INTA SpainArantxa Lopez Hospital Can Misses SpainCourtyard Room A B14 30 15 30Metagenomics and other culture independent tools to study virus communitiesJosefa Ant n Botella University of Alicante SpainCourtyard Room A B15 30 16 45PRACTICAL 2Nanopore 16S PCR cleanup finishing library preparation and starting sequencing run followed by Genomics Core Facility TourDaphne Welter EMBL Heidelberg Germany Laura Villacorta EMBL Heidelberg GermanyTraining Lab A B16 45 17 15BREAK17 15 19 15PRACTICAL 2Nanopore 16S analysis DNA cleanup and Sequencing startDaphne Welter EMBL Heidelberg Germany Laura Villacorta EMBL Heidelberg GermanyTraining Lab A BGeneCore Facility19 15 19 30Group activity Description of Case StudiesElisabeth Zielonka EMBL Heidelberg GermanyJos Eduardo Gonz lez Pastor Center of Astrobiology CSIC INTA SpainGiuseppe D Auria FISABIO SpainCourtyard Room A B19 40DINNER Hotel ISG Day 3 Wednesday 19 April 2023 Time Europe Berlin Speaker Location 09 00 09 15Quick overview of the dayJos Eduardo Gonz lez Pastor Center of Astrobiology CSIC INTA SpainCourtyard Room A B09 15 09 45PRACTICAL 1Test digestion conditions for metagenomic DNA and preparation of agarose gelsJos Eduardo Gonz lez Pastor Center of Astrobiology CSIC INTA SpainArantxa Lopez Hospital Can Misses SpainTraining Lab A B 09 45 11 00PRACTICAL 3Practical introduction Single cells genomics in dropletsTobias Wenzel EMBL Heidelberg GermanyTraining Lab A B11 00 11 15BREAK11 15 12 30PRACTICAL 1Digestion of metagenomic DNA for cloning in the libraries once that digestion conditions are determined Jos Eduardo Gonz lez Pastor Center of Astrobiology CSIC INTA SpainArantxa Lopez Hospital Can Misses SpainTraining Lab A B12 30 13 30LUNCHEMBL Canteen13 30 14 30PRACTICAL 1Purification from gel of the digested metagenomic DNAJos Eduardo Gonz lez Pastor Center of Astrobiology CSIC INTA SpainArantxa Lopez Hospital Can Misses SpainTraining Lab A B14 30 15 00BREAK15 00 17 00PRACTICAL 1Cloning of the metagenomic DNA overnight ligationEduardo Gonz lez Pastor Center of Astrobiology CSIC INTA SpainArantxa Lopez Hospital Can Misses SpainTraining Lab A B 17 00 19 30 PRACTICAL 3Practical single cell microbial genomics Droplet generation for single cell genomics and PCR set upTobias Wenzel EMBL Heidelberg GermanyTraining Lab A B19 30 20 30DINNER Hotel ISG Day 4 Thursday 20 April 2023 Time Europe Berlin Speaker Location 09 00 09 15 Quick overview of the dayJos Eduardo Gonz lez Pastor Center of Astrobiology CSIC INTA SpainCourtyard Room A B09 15 11 00 PRACTICAL 1Transformation in E coli of the libraryJos Eduardo Gonz lez Pastor Center of Astrobiology CSIC INTA SpainArantxa Lopez Hospital Can Misses SpainTraining Lab A B11 00 12 00 Methodological discussion of practical session 1 Metagenomics experimental design Common shortcoming and pitfallsJos Eduardo Gonz lez Pastor Center of Astrobiology CSIC INTA SpainCourtyard Room A B12 00 13 00 LUNCHEMBL Canteen13 00 14 30PRACTICAL 4Solving problems and questions Introduction to Linux and R based on pre recorded lecture 1 and 2Giuseppe D Auria FISABIO SpainTraining Lab A B14 30 15 30Metabolomic profiling of microbial communitiesMariana Reyes Prieto FISABIO SpainCourtyard Room A B15 30 16 00 BREAK16 00 17 00 Pacific Bioscience PacBio sequencing for metagenomicsVladimir Benes EMBL Heidelberg GermanyCourtyard Room A B18 15Bus leaves at 17 45Free evening with tour of Heidelberg Day 5 Friday 21 April 2023 Time Europe Berlin Speaker Location 09 00 09 15 Quick overview of the dayGiuseppe D Auria FISABIO SpainCourtyard Room A B09 15 10 00 PRACTICAL 1Analysis of some colonies from the metagenomic libraries Interpretation of resultsJos Eduardo Gonz lez Pastor Center of Astrobiology CSIC INTA SpainArantxa Lopez Hospital Can Misses SpainTraining Lab A B 10 00 10 30 BREAK10 30 11 15 Metatranscriptomics applied to the study microbial communitiesJos Eduardo Gonz lez Pastor Center of Astrobiology CSIC INTA SpainCourtyard Room A B11 15 12 00Case studiesCourtyard Room A B12 00 13 30 LUNCHEMBL Canteen13 30 14 30 Functional and taxonomic analysis with MgnifyLorna Richardson EMBL EBI Hinxton UKCourtyard Room A B14 30 16 30PRACTICAL 5Functional and taxonomic analysis with MgnifyGrisel Alejandra Escobar Zepeda EMBL EBI Hinxton UKLorna Richardson EMBL EBI Hinxton UKComputer Training Lab16 30 19 30 PRACTICAL 3Visualization of droplets and single cell analysis with flexible coffee breakTobias Wenzel EMBL Heidelberg GermanyTraining Lab A B19 30 22 00 BBQ DINNER Hotel ISG Day 6 Saturday 22 April 2023 Time Europe Berlin Speaker Location 09 00 09 15 Quick overview of the dayGiuseppe D Auria FISABIO SpainCourtyard Room A B09 15 11 00Introduction to 16S rDNA profiling Illumina PacBio Giuseppe D Auria FISABIO SpainComputer Training Lab11 00 11 15 BREAK11 15 12 15PRACTICAL 6Practical to 16S rDNA profiling Illumina PacBio Giuseppe D Auria FISABIO SpainComputer Training Lab12 15 13 15 LUNCHEMBL Canteen13 15 14 15PRACTICAL 6Practice to 16S rDNA profiling Illumina PacBio Giuseppe D Auria FISABIO SpainComputer Training Lab14 15 16 00PRACTICAL 7The microbial species definition and its challenges The MiGA web server for species identification the genome equivalent of RDP SilvaSSU web serversKostas Konstantinidis Georgia Institute of Technology USALuis Miguel Rodriguez R University of Innsbruck AustriaComputer Training Lab16 00 16 30 BREAK16 30 18 30 PRACTICAL 8Analysis of 100s of metagenomes shows that bacterial species existTools for specialized analyses of metagenomesKostas Konstantinidis Georgia Institute of Technology USALuis Miguel Rodriguez R University of Innsbruck AustriaComputer Training Lab18 30 20 00 Poster session 2 and dinnerHelix A and Rooftop Lounge Day 7 Sunday 23 April 2023 Time Europe Berlin Speaker Location 09 00 09 15 Quick overview of the dayKristian Vlahovicek University of Zagreb CroatiaCourtyard Room A B09 15 11 15 PRACTICAL 9Metagenomic assembly ORF finding functional annotationGiuseppe D Auria FISABIO SpainComputer Training Lab11 15 11 30 BREAK11 30 12 30 Analysis Tools Overview INCA MILC and MELPKristian Vlahovicek University of Zagreb CroatiaComputer Training Lab12 30 13 30 LUNCHEMBL Canteen13 30 15 30 PRACTICAL 10INCAKristian Vlahovicek University of Zagreb CroatiaComputer Training Lab15 30 16 00 BREAK16 00 18 00 Student presentation preparation time Case StudiesAll trainers and speakersCourtyard Room A B19 00DINNERDowntown Day 8 Monday 24 April 2023 Time Europe Berlin Speaker Location 09 00 09 15 Quick overview of the dayGiuseppe D Auria FISABIO SpainCourtyard Room A B09 15 10 15 Nanopore 16S sequencing results EPI2ME Laura Villacorta EMBL Heidelberg GermanyCourtyard Room A B10 15 10 45BREAK10 45 12 00 PRACTICAL 11MEGANDaniel Huson University of T bingen GermanyComputer Training Lab12 00 13 00LUNCHEMBL Canteen 13 00 14 00PRACTICAL 11MEGANDaniel Huson University of T bingen GermanyComputer Training Lab14 00 16 30Group activity and presentations Case StudiesCourtyard Room A B16 30 16 45BREAK16 45 17 15Wrap up and conclusionsCourtyard Room A B18 00DINNERHotel ISG Practical information Registration fees and motivation letter The course is limited to 20 participants For selection purposes please note that your application will not be considered without a letter of motivation Registration Registration fees include admission course materials COVID 19 safety measures meals and coffee breaks This EMBO course includes accommodation and transportation to and from the ISG Hotel to the venue Academia 500PhD Student 500Industry 1000 NO visa support letters will be issued until payment of the registration fee is confirmed Confirmation and payment The registration fee should be paid only after acceptance to the course The results will be announced approximately 2 3 weeks after the application deadline Motivation letter submission After you have logged in and successfully registered you will receive an email asking you to submit your motivation letter Click on the link provided and enter your motivation letter in the text box provided Alternatively you can submit your motivation letter by clicking on the link on the confirmation page directly after registering Instructions Include your relevant skills experience and qualifications showing why you would be suitable for the course Explain why you would like to attend including what you can contribute and how you think you will benefit from the course Please note The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised For detailed instructions please watch our video on how to submit a course motivation letter Further details For further information about registration and motivation letter submission please refer to the FAQ page Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of both registration fee waivers and travel grants Availability is limited to participants attending on site EMBL Courses and virtual or on site EMBO Practical Courses in Heidelberg and will be indicated during the motivation letter submission process Your place in the course is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course Travel grant The travel grant will cover the cost of travel airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Course within Europe up to 1000 for participants travelling to an EMBL Course from outside Europe up to 500 for any participant travelling to an EMBO Practical Course up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Practical Course up to 700 for any participant working in Croatia Czech Republic Estonia Greece Hungary Italy Lithuania Luxembourg Poland Slovenia and Turkey travelling to an EMBO Practical Course Registration fees are only covered for EMBO Practical Courses The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant EMBO Practical Courses only For EMBO Practical Course participants with children there is the possibility to apply for a childcare grant to offset child care costs incurred by participants or speakers when participating at a course Eligible costs include fees for a babysitter or child care facility travel costs for a caregiver or travel costs for taking the child to the meeting etc Please note that priority will be given to early stage researchers A maximum amount of 500 can be awarded per participant applying for an EMBO childcare grant Boehringer Ingelheim Fonds travel grant Applies to selected courses only Availability will be indicated during the motivation letter submission process This grant covers costs related to your attendance at the course registration travel and accommodation costs The grant is restricted to PhD students and postdocs who conduct basic biomedical research Whether you are eligible to apply for a travel grant depends on when you received your university entrance qualification e g Abitur A Levels High School Diploma Final State Examination for PhD and MD students as well as graduates the university entrance qualification must not have been obtained more than 11 years ago at the time of the envisaged course for postdocs the university entrance qualification must not have been obtained more than 13 years ago at the time of the envisaged course Application You may apply for financial assistance when submitting your motivation letter for courses In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application For the Boehringer Ingelheim Fonds Travel Grant there is a pre application question during the motivation letter submission process and if selected you will be requested to complete a standard form and documentation consisting of your travel expense estimation Selection The scientific organisers will select the recipients of all financial assistance during the motivation letter selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the course Selection is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details See our list of external funding opportunities and for further information about financial assistance please refer to the FAQ page Accommodation and shuttles Hotel Accommodation has been pre booked for you at the ISG Hotel for the default dates of 16 April to 24 April 2023 9 nights Please note that the course registration fee includes coverage of accommodation costs in twin rooms including breakfasts for your stay at the ISG In case you would like to have a single room please let us know and please note that you will be required to pay an additional cost of 31 per night This should be paid by you directly to the ISG during your stay Any additional nights need to be booked and paid for by you We recommend that all course participants stay at the ISG Hotel which is the dedicated hotel for the course Local transport Shuttle buses will go from the ISG Hotel to EMBL and back mornings and evenings Please see the schedule here Further details Address EMBL Heidelberg Meyerhofstra e 1 69117 Heidelberg GermanyFor further information on getting to EMBL Heidelberg visit our Travel Information page For enquiries about accommodation and local transportation please refer to the FAQ page Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page COVID 19 related questions COVID 19 information for on site events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Event partners Event sponsors Event supporters Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other events or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9...

Vladimir Benes, Giuseppe D´Auria, José Eduardo González-Pastor, Elisabeth Zielonka

EMBO Practical Course

EMBL Heidelberg

17 April - 18 April 2023

EuroFAANG AQUA-FAANG workshop: methods to use and reuse the AQUA-FAANG data and Ensembl resources to advance science

Edit

April 17, 2023 00:002023CourseVirtual

Description This one and a half day workshop will provide detailed training on methods to use and reuse the wealth of data generated by the EuroFAANG AQUA FAANG project AQUA FAANG aims to improve understanding the genome function and usage of genotype to phenotype prediction in the six most important European farmed fish species EUROPEAN SEABASS GILTHEAD SEABREAM RAINBOW TROUT ATLANTIC SALMON COMMON CARP TURBOT The workshop will primarily focus on the comprehensive and integrated annotation of these six species by the Ensembl genome browser The course will also include a deeper dive from the Ensembl analysis teams into gene annotation and regulation and demonstrations of the specific analyses and research conducted by AQUA FAANG scientists...

Peter Harrison

Virtual

12 April 2023

Pangenomics and machine learning for crop improvement

Edit

April 12, 2023 10:002023WebinarVirtual

Description The changing climate and increasing human population mean that we need to accelerate the production of improved crop varieties Advances in genomics and phenomics are helping to accelerate crop improvement but the quantity and diversity of data being generated is vast and needs new methods for integrated analysis Artificial intelligence AI approaches provide one solution to this analysis challenge This webinar will provide an overview on recent advances in pangenomics and application of machine learning and deep learning for crop genomic and phenomic data analysis...

Dave Edwards

Virtual

28 March - 31 March 2023

Visualizing biological data (VIZBI 2023)

Edit

March 28, 2023 00:002023ConferenceEMBL Heidelberg, Virtual

Description This conference will take place at EMBL Heidelberg with the option to attend virtually Please see EMBL s COVID 19 safety recommendations if attending the on site event Conference overview Visualisation is increasingly important in life science as data grows rapidly in volume and complexity The VIZBI initiative is an international conference series bringing together researchers developing and using computational visualisation to address a broad range of biological research areas the conference also attracts participation from medical illustrators graphic designers and graphic artists VIZBI is held annually usually alternating between Europe and the USA More information on VIZBI can be found at https vizbi org...

Barbora Kozlikova, Marc A. Marti-Renom, Andrea Schafferhans, Nico Scherf, Michelle Scott, Srigokul Upadhyayula

EMBO Workshop

EMBL Heidelberg, Virtual

28 March - 31 March 2023

Introduction to metabolomics analysis

Edit

March 28, 2023 00:002023CourseEMBL-EBI

Description This course will provide an introduction to metabolomics through lectures and hands on sessions using publicly available data software and tools Participants will become familiar with the current state of experimental design data acquisition LC MS MS imaging processing and modelling In addition they will learn about community standards and sharing in metabolomics particularly through using the EMBL EBI s MetaboLights repository and Galaxy infrastructure Participants will learn through hands on tutorials to use tools available for data analysis and data submission Additionally case studies will be used to discuss and show how to employ the week s learning In person course We plan to deliver this course in an in person manner onsite at our training suite at EMBL EBI Hinxton Please be aware that we are continually evaluating the ongoing pandemic situation and as such may need to change the format of courses at short notice Your safety is paramount to us you can read our COVID guidance policy for more information All information is correct at time of publishing Additional information The course fee is inclusive of three nights accommodation and catering including dinner Please note that we will operate this course face to face at EMBL EBI Hinxton Hybrid options are not currently available We reserve the right to change the format of this course or cancel it due to the ongoing coronavirus pandemic Please also note that there are delays in the issuing of visas from the UK Government We encourage you to check if you need a visa and apply in plenty of time before travelling Current waiting times are more than six weeks For more information please visit the UK Government website...

Jane Reynolds

EMBL-EBI

26 March - 1 April 2023

Measuring translational dynamics by ribosome profiling

Edit

March 26, 2023 00:002023CourseEMBL Heidelberg

Description OverviewSpeakers trainers and staffProgrammePractical informationSponsorsMedia kit Overview Please see EMBL s COVID 19 safety policy for testing and other requirements to attend this on site course Course overview Regulation of translation is key in the control of gene expression playing a critical role in many biological and pathophysiological settings In the last decade methodological advances have provided comprehensive insights into cellular transcriptomes and proteomes however the systems wide analysis of translation remained an unsolved experimental challenge The advent of ribosome profiling provided the methodological basis for comprehensive transcriptome wide analyses of translation at sub codon resolution by the precise and high throughput determination of ribosomal positions on mRNA Its application in a variety of organisms yielded novel insights into protein synthesis and its dynamic regulation significantly advancing our understanding of the post transcriptional regulation of gene expression Audience The course is aimed at PhD students and early post doctoral researchers who are entering the field of posttranscriptional regulation of gene expression Learning outcomes The practical course Measuring translational dynamics by ribosome profiling aims to a generate a detailed theoretical understanding of ribosome profiling its variations to address specific aspects of translation and its experimental strengths and limitations b provide hands on wet lab training to perform ribosome profiling experiments with the aim to understand and master the critical steps of the experimental workflow and to train the participants to independently perform and adapt similar experiments in their own laboratories c provide hands on bioinformatics training on processing the high throughput sequencing data the quality control and on the use of specialised tools for data generated by ribosome profiling Speakers trainers and staff Pavel Baranov University College Cork Ireland Vladimir Benes EMBL Heidelberg Germany Alla Fedorova University College Cork Ireland Rachel Green Johns Hopkins University School of Medicine USA Nicholas Ingolia University of California Berkeley USA Yeji Kim University of Bern Switzerland Leon Kleemann University of Bern Switzerland Sebastian Leidel University of Bern Switzerland Jan Medenbach University of Regensburg Germany Andreas Meindl University of Regensburg Germany Marina Rodnina Max Planck Institute for Biophysical Chemistry Germany Noam Stern Ginossar Weizmann Institute of Science Israel Jack Tierney University College Cork Ireland Michael VanInsberghe Hubrecht Institute KNAW Netherlands Anne Willis MRC Toxicology UK Oza Zaheed University College Cork Ireland Elisabeth Zielonka EMBL Heidelberg Germany Scientific organisers Pavel Baranov University College Cork Ireland Sebastian Leidel University of Bern Switzerland Jan Medenbach University of Regensburg Germany Elisabeth Zielonka EMBL Heidelberg Germany Course organisers Irena Provaznikova Training Lab Technician EMBL Heidelberg Germany Aline Schnieder Course and Conference Officer EMBL Heidelberg Germany Programme Got something to say Tweet it with EMBORiboProf Some pre course work such as watching pre recordings protocol reading and computational exercises with estimated time 0 10 hours will be required and will be shared in advance of the course Some speakers may need to join virtually to give their lecture or Q A and the programme is subject to change Day 0 Monday 13 March 2023 Time Europe Berlin SessionLocation14 00 15 30Onboarding session Welcome introduction to material and software testing Virtual Day 1 Sunday 26 March 2023 Time Europe Berlin SessionLocation13 15Bus to EMBL ATCISG Hotel13 30 14 00Registration and light refreshmentsCourtyard A B14 00 14 30Welcome and house notes and course overviewPavel Baranov University College Cork IrelandSebastian Leidel University of Bern SwitzerlandJan Medenbach University of Regensburg GermanyElisabeth Zielonka EMBL Heidelberg GermanyCourtyard A B14 30 15 00Ice Breaking activityCourtyard A B15 00 15 30Coffee BreakCourtyard A B15 30 16 00Introduction Lecture Overview of the course and technology backgroundPavel Baranov University College Cork IrelandSebastian Leidel University of Bern SwitzerlandJan Medenbach University of Regensburg GermanyCourtyard A B16 00 17 00LectureJan Medenbach University of Regensburg GermanyCourtyard A B17 00 18 00LectureSebastian Leidel University of Bern SwitzerlandCourtyard A B18 00 20 00Flash talks by participants speakers and trainersCourtyard A B20 00Bus to ISG HotelATC Entrance20 15 21 30Dinner NetworkingISG Hotel Day 2 Monday 27 March 2023 Time Europe Berlin SessionLocation08 10Bus to EMBL ATCISG Hotel08 30 08 45Laboratory Safety InstructionsCourtyard A B08 45 09 00Overview of the day introduction to practical workCourtyard A B09 00 10 00Practical work preparation of RPFs Native extract preparationLeon Kleemann University of Bern Switzerland Sebastian Leidel University of Bern Switzerland Jan Medenbach University of Regensburg Germany Andreas Meindl University of Regensburg Germany Elisabeth Zielonka EMBL Heidelberg GermanyTraining Lab A B10 00 10 30Coffee BreakCourtyard A B10 30 11 30Practical work preparation of RPFs Extract quantification ribonuclease digestion preparation of gradientsLeon Kleemann University of Bern Switzerland Sebastian Leidel University of Bern Switzerland Jan Medenbach University of Regensburg Germany Andreas Meindl University of Regensburg Germany Elisabeth Zielonka EMBL Heidelberg Germany Training Lab A B11 30 12 00Practical work preparation of RPFs Start of ultracentrifugationLeon Kleemann University of Bern Switzerland Sebastian Leidel University of Bern Switzerland Jan Medenbach University of Regensburg Germany Andreas Meindl University of Regensburg Germany Elisabeth Zielonka EMBL Heidelberg Germany Training Lab A B12 00 13 00Lunch breakEMBL Canteen13 00 15 30Computer Class Raw Data processing assessment of sequence data quality adaptors removal removal of rRNA and tRNA reads PCR duplicates removal using UMIs read mapping to genomes and transcriptomesPavel Baranov University College Cork IrelandAlla Fedorova University College Cork IrelandJack Tierney University College Cork IrelandOza Zaheed University College Cork Ireland Computer Training Lab15 30 16 00Coffee BreakCourtyard A B16 00 17 00Lecture remote Nicholas Ingolia University of California Berkeley USACourtyard A B17 00 19 00Practical work preparation of RPFsGradient fractionation and RNA preparationLeon Kleemann University of Bern Switzerland Sebastian Leidel University of Bern Switzerland Jan Medenbach University of Regensburg Germany Andreas Meindl University of Regensburg Germany Elisabeth Zielonka EMBL Heidelberg Germany Training Lab A B19 00 21 00Poster Session Discussion concurrent finger food dinner and drinksATC Helix A Rooftop Lounge21 00Bus to ISG HotelATC Entrance Day 3 Tuesday 28 March 2023 Time Europe Berlin SessionLocation08 40Bus to EMBL ATCISG Hotel09 00 09 15Overview of the dayCourtyard A B09 15 11 00Practical work preparation of RPFsSize selection of RPFs by PAGELeon Kleemann University of Bern Switzerland Sebastian Leidel University of Bern Switzerland Jan Medenbach University of Regensburg Germany Andreas Meindl University of Regensburg Germany Elisabeth Zielonka EMBL Heidelberg Germany Training Lab A B11 00 11 30Coffee breakCourtyard A B11 30 12 30Lecture Translation A tug war during viral infectionNoam Stern Ginossar Weizmann Institute of Science IsraelCourtyard A B12 30 13 00Practical work preparation of RPFsGel extraction setup over night incubation Leon Kleemann University of Bern Switzerland Sebastian Leidel University of Bern Switzerland Jan Medenbach University of Regensburg Germany Andreas Meindl University of Regensburg Germany Elisabeth Zielonka EMBL Heidelberg Germany Training Lab A B13 00 14 00Lunch breakEMBL Canteen14 00 16 00Computer Class Quality Assessments Analysis of read mapping across different functional regions read length distribution and triplet periodicity metagen profiles for the assessment of global translationPavel Baranov University College Cork IrelandAlla Fedorova University College Cork IrelandJack Tierney University College Cork IrelandOza Zaheed University College Cork Ireland Computer Training Lab16 00 16 30Coffee breakCourtyard A B16 30 17 30Lecture remote Rachel Green Johns Hopkins University School of Medicine USACourtyard A B17 30 19 00Interactive discussion round Responsible conduct of research sources of experimental artifacts the technology in different species what are the key quality controls parameter space for optimizationCourtyard A B19 00 21 00Poster Session Discussion concurrent finger food dinner and drinksATC Helix A Rooftop Lounge21 00Bus to ISG HotelATC Entrance Day 4 Wednesday 29 March 2023 Time Europe Berlin SessionLocation08 40Bus to EMBL ATCISG Hotel09 00 09 15Overview of the dayCourtyard A B09 15 10 45Practical work Library Preparation Dephosphorylation linker ligationLeon Kleemann University of Bern Switzerland Sebastian Leidel University of Bern Switzerland Jan Medenbach University of Regensburg Germany Andreas Meindl University of Regensburg Germany Elisabeth Zielonka EMBL Heidelberg Germany Training Lab A B10 45 11 15Coffee breakCourtyard A B11 15 13 15Computer Class Goal oriented data analysis Differential gene expression detection of translated ORFs translational pauses codon specific decoding ratesPavel Baranov University College Cork IrelandAlla Fedorova University College Cork IrelandJack Tierney University College Cork IrelandOza Zaheed University College Cork Ireland Computer Training Lab13 15 14 15Lunch breakEMBL Canteen14 15 15 15Lecture Junk translation translation of junk and translation that does not make proteinsPavel Baranov University College Cork IrelandCourtyard A B15 15 16 15LectureVladimir Benes EMBL Heidelberg GermanyCourtyard A B16 15 16 45Bus downtownATC Entrance16 45 18 45Guided tour of Heidelberg free time downtown18 45 21 15Course dinner Day 5 Thursday 30 March 2023 Time Europe Berlin SessionLocation08 40Bus to EMBL ATCISG Hotel09 00 09 15Overview of the dayCourtyard A B09 15 11 15Practical work Library preparationsubtractive hybridization 1st purification solid phase extraction reverse transcriptionLeon Kleemann University of Bern Switzerland Sebastian Leidel University of Bern Switzerland Jan Medenbach University of Regensburg Germany Andreas Meindl University of Regensburg Germany Elisabeth Zielonka EMBL Heidelberg Germany Training Lab A B11 15 11 45Coffee breakCourtyard A B11 45 13 15Practical Work Library preparation2nd purification solid phase extraction circularization of RT productLeon Kleemann University of Bern Switzerland Sebastian Leidel University of Bern Switzerland Jan Medenbach University of Regensburg Germany Andreas Meindl University of Regensburg Germany Elisabeth Zielonka EMBL Heidelberg Germany Training Lab A B13 15 14 15Lunch breakEMBL Canteen14 15 15 15Guided tour of the EMBL genomics core facility Genecore Genecore15 15 16 15Practical Work Library preparation3rd purification solid phase extraction pre amplification PCRLeon Kleemann University of Bern Switzerland Sebastian Leidel University of Bern Switzerland Jan Medenbach University of Regensburg Germany Andreas Meindl University of Regensburg Germany Elisabeth Zielonka EMBL Heidelberg Germany Training Lab A B16 15 16 45Coffee breakCourtyard A B16 45 17 45Lecture remote Anne Willis MRC Toxicology UKCourtyard A B17 45 18 15Practical Work Library preparation purification of PCR productLeon Kleemann University of Bern Switzerland Sebastian Leidel University of Bern Switzerland Jan Medenbach University of Regensburg Germany Andreas Meindl University of Regensburg Germany Elisabeth Zielonka EMBL Heidelberg Germany Training Lab A B18 15 19 15DinnerEMBL Canteen19 15 20 45Discussion round Responsible conduct of research protocol optimization the technology in different model organisms future applicationsCourtyard A B20 45Bus to ISG HotelATC Entrance Day 6 Friday 31 March 2023 Time Europe Berlin SessionLocation08 40Bus to EMBL ATCISG Hotel09 00 09 15Overview of the dayCourtyard A B09 15 10 15Lecture Translation dynamics and protein folding Marina Rodnina MPI Biophysical Chemistry GermanyCourtyard A B10 15 10 45Coffee breakCourtyard A B10 45 11 30Practical Work Library preparation Scouting PCR preparation of gelsLeon Kleemann University of Bern Switzerland Sebastian Leidel University of Bern Switzerland Jan Medenbach University of Regensburg Germany Andreas Meindl University of Regensburg Germany Elisabeth Zielonka EMBL Heidelberg Germany Training Lab A B11 30 13 00Computer Class The use of public data resources riboSeq Org and beyondPavel Baranov University College Cork IrelandAlla Fedorova University College Cork IrelandJack Tierney University College Cork IrelandOza Zaheed University College Cork Ireland Computer Training Lab13 00 14 00Lunch breakEMBL Canteen14 00 15 30Discussion round Data analyses artifactsCourtyard A B15 30 16 00Practical Work Library preparationAnalysis of PCR products by PAGELeon Kleemann University of Bern Switzerland Sebastian Leidel University of Bern Switzerland Jan Medenbach University of Regensburg Germany Andreas Meindl University of Regensburg Germany Elisabeth Zielonka EMBL Heidelberg Germany Training Lab A B16 00 16 30Coffee breakCourtyard A B16 30 18 00Practical Work Library preparation Analysis of PCR products by PAGE continued final discussion on library preparationLeon Kleemann University of Bern Switzerland Sebastian Leidel University of Bern Switzerland Jan Medenbach University of Regensburg Germany Andreas Meindl University of Regensburg Germany Elisabeth Zielonka EMBL Heidelberg Germany Training Lab A B18 00 19 00Open discussion Responsible conduct of research data analysis bottlenecks and artifacts data management FAIR principle user defined questionsCourtyard A B19 00Bus to ISG HotelATC Entrance19 15 21 15Dinner and networkingISG Hotel Day 7 Saturday 1 April 2023 Time Europe Berlin SessionLocation08 40Bus to EMBL ATCISG Hotel09 00 09 15Overview of the dayCourtyard A B09 15 10 15Lecture Ribosome profiling in single cellsMichael VanInsberghe Hubrecht Institute KNAWCourtyard A B10 15 10 45Coffee breakComputer Training Lab10 45 11 45Computer Class Datamining competition I Identifying evidence of non standard translation mechanisms student presentations of results Pavel Baranov University College Cork IrelandAlla Fedorova University College Cork IrelandJack Tierney University College Cork IrelandOza Zaheed University College Cork Ireland Computer Training Lab11 45 12 45Lunch breakEMBL Canteen12 45 15 15Computer Class Datamining competition II Identifying evidence of non standard translation mechanisms student presentations of results Pavel Baranov University College Cork IrelandAlla Fedorova University College Cork IrelandJack Tierney University College Cork IrelandOza Zaheed University College Cork Ireland Computer Training Lab15 15 16 15Open discussion and feedbackCourtyard A B16 15End of course bus to main stationATC Entrance Practical information Registration fees and motivation letter The course is limited to 18 participants For selection purposes please note that your application will not be considered without a letter of motivation Registration Registration fees include admission course materials COVID 19 safety measures meals and coffee breaks This EMBO course includes accommodation and transportation to and from the ISG Hotel to the venue Academia 500PhD Student 500Industry 1000 NO visa support letters will be issued until payment of the registration fee is confirmed Confirmation and payment The registration fee should be paid only after acceptance to the course The results will be announced approximately 2 3 weeks after the application deadline Motivation letter submission After you have logged in and successfully registered you will receive an email asking you to submit your motivation letter Click on the link provided and enter your motivation letter in the text box provided Alternatively you can submit your motivation letter by clicking on the link on the confirmation page directly after registering Instructions Include your relevant skills experience and qualifications showing why you would be suitable for the course Explain why you would like to attend including what you can contribute and how you think you will benefit from the course Please note The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised For detailed instructions please watch our video on how to submit a course motivation letter Further details For further information about registration and motivation letter submission please refer to the FAQ page Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of both registration fee waivers and travel grants Availability is limited to participants attending on site EMBL Courses and virtual or on site EMBO Practical Courses in Heidelberg and will be indicated during the motivation letter submission process Your place in the course is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course Travel grant The travel grant will cover the cost of travel airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Course within Europe up to 1000 for participants travelling to an EMBL Course from outside Europe up to 500 for any participant travelling to an EMBO Practical Course up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Practical Course up to 700 for any participant working in Croatia Czech Republic Estonia Greece Hungary Italy Lithuania Luxembourg Poland Slovenia and Turkey travelling to an EMBO Practical Course Registration fees are only covered for EMBO Practical Courses The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant EMBO Practical Courses only For EMBO Practical Course participants with children there is the possibility to apply for a childcare grant to offset child care costs incurred by participants or speakers when participating at a course Eligible costs include fees for a babysitter or child care facility travel costs for a caregiver or travel costs for taking the child to the meeting etc Please note that priority will be given to early stage researchers A maximum amount of 500 can be awarded per participant applying for an EMBO childcare grant Boehringer Ingelheim Fonds travel grant Applies to selected courses only Availability will be indicated during the motivation letter submission process This grant covers costs related to your attendance at the course registration travel and accommodation costs The grant is restricted to PhD students and postdocs who conduct basic biomedical research Whether you are eligible to apply for a travel grant depends on when you received your university entrance qualification e g Abitur A Levels High School Diploma Final State Examination for PhD and MD students as well as graduates the university entrance qualification must not have been obtained more than 11 years ago at the time of the envisaged course for postdocs the university entrance qualification must not have been obtained more than 13 years ago at the time of the envisaged course Application You may apply for financial assistance when submitting your motivation letter for courses In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application For the Boehringer Ingelheim Fonds Travel Grant there is a pre application question during the motivation letter submission process and if selected you will be requested to complete a standard form and documentation consisting of your travel expense estimation Selection The scientific organisers will select the recipients of all financial assistance during the motivation letter selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the course Selection is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details See our list of external funding opportunities and for further information about financial assistance please refer to the FAQ page Accommodation and shuttles Hotel Accommodation has been pre booked for you at the ISG Hotel for the default dates of 26 March to 1 April 2023 6 nights Please note that the course registration fee includes coverage of accommodation costs in twin rooms including breakfasts for your stay at the ISG but that you will be required to pay an additional cost of 31 EUR per night for a single room This should be paid by you directly to the ISG during your stay Any additional nights need to be booked and paid for by you We recommend that all course participants stay at the ISG Hotel which is the dedicated hotel for the course Local transport Shuttle buses will go from the ISG Hotel to EMBL and back mornings and evenings A bus schedule and location of the bus stops will be made available prior to the meeting Further details Address EMBL Heidelberg Meyerhofstra e 1 69117 Heidelberg GermanyFor further information on getting to EMBL Heidelberg visit our Travel Information page For enquiries about accommodation and local transportation please refer to the FAQ page Event software Event software The EMBL eCampus learning platform will be used to collaborate communicate and network with all of the course participants All participants will receive information on how to join shortly before the course We recommend using Chrome Safari or Mozilla Firefox browsers for eCampus Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page COVID 19 related questions COVID 19 information for on site events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Event partners Event sponsors Event supporters Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other events or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9...

Pavel Baranov, Sebastian Leidel, Jan Medenbach, Elisabeth Zielonka

EMBO Practical Course

EMBL Heidelberg

23 March 2023

Development of a virtual Rheumatoid Arthritis synovial fibroblast for large-scale dynamic analysis and efficient drug-target identification

Edit

March 23, 2023 15:002023WebinarVirtual

Description Rheumatoid arthritis RA is a complex systemic autoimmune disease that primarily affects the lining of the synovial joints and involves an intricate interplay among genotype and environmental triggers Early RA starts with the infiltration of the synovial compartment by leukocytes Then the synovial fluid is inundated with pro inflammatory mediators inducing an inflammatory cascade characterised by fibroblast like synoviocytes FLS interactions with cells of the innate and adaptive immune system Cytokines are key mediators whereas drugs inhibiting these cytokines lead to RA therapies Unfortunately 40 of patients fail to respond to therapy Recently many studies have shown that RA FLS activation and the subsequent joint damage they perpetuate are associated with an altered metabolism that may be therapeutically targetable Thus RA FLS directed therapies could become a complementary approach to immune directed therapies I will present our efforts to construct a virtual RA FLS and develop a computational method to simulate large scale coupled logical and metabolic models using Boolean and constraint based modelling The digital RA FLS can be used to predict intervention points for minimising the sustained inflammation bone erosion and cartilage destruction and identify druggable metabolic switches that could help us reprogram these cells to acquire an anti inflammatory phenotype About the speaker Dr Anna Niarakis is an Associate Professor HDR at UEVE Paris Saclay affiliated with GenHotel European Research Laboratory for Rheumatoid Arthritis Genopole She holds a 3 year delegation for research at INRIA in the group Lifeware She has a broad scientific background in Biochemistry Biology and Pharmaceutical Technology and post doctoral studies in Computational Systems Biology Bioinformatics with expertise in complex human diseases She is a co leader of the Disease Maps consortium an active member of CoLoMoTo Consortium for Logical Modelling Tools and a former coordinator of SysMod Systems Modelling...

Anna Niarakis

Virtual

22 March 2023

Single-cell and spatial omics technologies in plant science

Edit

March 22, 2023 15:302023WebinarVirtual

Description Recent technological advances in single cell and spatial omics have revolutionised how we study biology by enabling researchers to see what used to be hidden behind the heterogeneity within the tissue Such technologies have been readily applied to study plants recently This webinar will showcase the application of single cell multiomics transcriptome and epigenome and spatial transcriptomics in plant research focusing on the development of a plant cell atlas and the understanding of plant microbe interactions...

Tatsuya Nobori

Virtual

21 March 2023

Edit

March 12, 2023 00:002023CourseEMBL Heidelberg

Description OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview Course overview A rapidly increasing number of researchers aim to purify and identify extracellular vesicles and many methodologies to isolate and analyse these vesicles are available and have been implemented This course will cover the basics possibilities and limitations of different purification and characterisation techniques and will address strategies to understand their role in biomedical applications Audience This course is intended for PhD students and Postdoctoral researchers who are interested in learning how to work with extracellular vesicles and know more about their biomedical applications Modules resources Extracellular vesicles continuous and discontinuous density gradient ultracentrifugation ultrafiltration techniques bead capture and precipitation techniques size exclusion chromatography SEC Extracellular vesicles characterisation Immunoblot and electron microscopy fluorescent labeling quantitative and qualitative analysis by flow cytometry nanoparticle tracking analysis in vivo imaging proteomic and transcriptomic analysis of EV Extracellular vesicles composition lipidomics proteomics transcriptomics Extracellular vesicles and function molecular players for extracellular vesicle biogenesis extracellular vesicle targeting to cells extracellular vesicles as diagnostics and or therapeutics in pathophysiology Learning outcomes In this course we intend to make PhD students and post doctoral researchers familiar with good practice guidelines and methods for purification and identification of extracellular vesicles with practical sessions included What past participants say about the course This course was very informative and covers all the major aspects of EV research It addresses questions of what level of quality is required for good publications but also offers relevant approaches towards analysing data and critical thinking in the EV field Whether you are taking your first steps in this field or more experienced this course applies to you Dr Berglind Eva Benediktsd ttir University of Iceland Iceland My research is focused on understanding the role of exosomes in the progression of glioblastoma While working on exosome mediated regulation of angiogenesis in glioblastoma I found significant difficulties in getting a pure population of exosomes as it is often contaminated with other biomolecules As a result we were in delusion whether the data which we were getting was the effect of exosomes or other biomolecules Fortunately I found the EMBO Practical Course on extracellular vesicles focusing on the isolation and purification of extracellular vesicles which was extremely important for my research work We were trained to use cutting edge research tools for extracellular vesicles and learned bioinformatic analysis of biomolecules that are present in exosomes I also got an opportunity to interact with world leading researchers and discuss my research Abir Mondal National Centre for Cell Science India Speakers Speakers trainers and staff Edit Buz s Semmelweis University Hungary Ana s B cot Institute of Psychiatry and Neuroscience of Paris France Sarah Deville Ghent University Belgium Virtual trainer Olivier De Wever Ghent University Belgium Mario Gimona Paracelsus Medical University Austria Andr G rgens Karolinska Institutet Sweden An Hendrix Ghent University Belgium Maribel Lara Corona Institute of Psychiatry and Neuroscience of Paris France Cecilia L sser University of Gothenburg Sweden Virtual speaker Estefan a Lozano Andr s Utrecht University The Netherlands Suresh Mathivanan La Trobe University Australia Esther Nolte t Hoen Utrecht University The Netherlands Michiel Pegtel Amsterdam UMC The Netherlands Cl udio Pinheiro Ghent University Belgium Johan Swinnen KU Leuven Belgium Guillaume Van Niel Institute of Psychiatry and Neuroscience of Paris France Marca Wauben Utrecht University The Netherlands Scientific organisers An Hendrix Ghent University Belgium Esther Nolte t Hoen Utrecht University The Netherlands Guillaume Van Niel Institute of Psychiatry and Neuroscience of Paris France Course organisers Raili Pall Course and Conference Officer EMBL Heidelberg Germany Swetlana Krez Training Lab Manager EMBL Heidelberg Germany Programme Got something to say Tweet it EMBOEVs Some pre course work such as watching pre recordings protocol reading and computational exercises with estimated time 0 10 hours will be required and will be shared in advance of the course Some speakers may need to join virtually to give their lecture or Q A and the programme is subject to change Day 1 Sunday 12 March 2023 Time Europe Berlin SpeakerLocation16 00 16 30Registration ISG Hotel16 30 17 00Welcome house notesISG Hotel17 00 19 00Flash talks by participants Ice breaker exerciseISG Hotel19 00Buffer dinner NetworkingISG Hotel Day 2 Monday 13 March 2023 Time Europe Berlin SpeakerLocation08 40Bus from ISG hotel to EMBLISG hotel bus stop08 50 09 00Safety instructionsSwetlana Krez EMBL Heidelberg GermanyCourtyard Room A B09 00 09 15 Outline of the dayAn Hendrix Ghent University BelgiumCourtyard Room A B09 15 10 00Lecture Heterogeneity in EV methodsAn Hendrix Ghent University BelgiumCourtyard Room A B 10 00 10 30Coffee break10 30 11 15Lecture Heterogeneity in EV subtypesEdit Buzas Semmelweis University HungaryCourtyard Room A B 11 15 11 45Introduction to practicals andseparation methodsAn Hendrix Ghent University Belgium Courtyard Room A B 11 45 12 45Lunch break EMBL Canteen12 45 13 45Practical 1 Preparation of EVs by differential ultracentrifugationTraining Lab A B 13 45 14 30Lecture Fluorescent labeling of EVsEsther Nolte t Hoen Utrecht University The NetherlandsCourtyard Room A B 14 30 15 30Practical 1 Fluorescent labelingTrainers An Hendrix Esther Nolte t Hoen Ana s B cot Cl udio Pinheiro Estefania Lozano Andr s Maribel Lara CoronaTraining Lab A B 15 30 16 15Lecture EV biogenesisGuillaume Van Niel Institute of Psychiatry and Neuroscience of Paris FranceCourtyard Room A B 16 15 16 45Coffee break16 45 17 30Lecture RNA sorting in EVsEsther Nolte t Hoen Utrecht University The NetherlandsCourtyard Room A B 17 30 19 45Practical 2 EV separation using Optiprep density gradient centrifugationTrainers An Hendrix Esther Nolte t Hoen Ana s B cot Cl udio Pinheiro Estefania Lozano Andr s Maribel Lara CoronaTraining Lab A B19 45 20 45DinnerEMBL canteen20 45Bus from EMBL to ISG hotelEMBL bus stop Day 3 Tuesday 14 March 2023 Time Europe Berlin SpeakerLocation08 40Bus from ISG hotel to EMBLISG hotelbus stop09 00 09 15Outline of the dayGuillaume Van Niel Institute of Psychiatry and Neuroscience of Paris France Courtyard Room A B 09 15 10 25 Practical 3 EV separation using size exclusion chromatographyTrainers An Hendrix Esther Nolte t Hoen Ana s B cot Cl udio Pinheiro Estefania Lozano Andr s Maribel Lara CoronaTraining Lab A B 10 25 10 35Practical ONI CHIP demonstration and addition of EVs Training Lab A B 10 35 10 55 Coffee break10 55 12 00 Practical 2 continuation Collect and process fractions from density gradientsTrainers An Hendrix Esther Nolte t Hoen Ana s B cot Cl udio Pinheiro Estefania Lozano Andr s Maribel Lara Corona Training Lab A B 12 00 12 45Lecture Quantitative and qualitative EV analysis by flow cytometryMarca Wauben Utrecht University The Netherlands Virtual Speaker Courtyard Room A B 12 45 13 45Lunch breakEMBL Canteen13 45 14 30Lecture Single EV analysisAndr G rgens Karolinska Institutet SwedenCourtyard Room A B 14 30 15 45 Practical 4 Particle analysis rotation 1 Trainers An Hendrix Esther Nolte t Hoen Ana s B cot Cl udio Pinheiro Estefania Lozano Andr s Maribel Lara CoronaTraining Lab A B15 45 16 15 Coffee break16 15 17 30 Practical 4 continuation Particle analysis rotation 2 Trainers An Hendrix Esther Nolte t Hoen Ana s B cot Cl udio Pinheiro Estefania Lozano Andr s Maribel Lara CoronaTraining Lab A B17 30 18 45Practical 4 continuation Particle analysis rotation 3 Trainers An Hendrix Esther Nolte t Hoen Ana s B cot Cl udio Pinheiro Estefania Lozano Andr s Maribel Lara CoronaTraining Lab A B18 45 19 30 Tapas dinner ATC Foyer 19 30 21 30Poster session I ODD numbers with drinksATC Foyer21 30Bus from EMBL to ISG hotelEMBL bus stop Day 4 Wednesday 15 March 2023 Time Europe Berlin SpeakerLocation08 40Bus from ISG hotel to EMBLISG hotel bus stop09 00 09 15Outline of the dayEsther Nolte t Hoen Utrecht University The NetherlandsCourtyard Room A B 09 15 10 15Practical 8 Data Analysis in 3 groups Trainers An Hendrix Esther Nolte t Hoen Ana s B cot Cl udio Pinheiro Estefania Lozano Andr s Maribel Lara Corona Guillaume Van NielCourtyard Room A B Flexlab A B Seminar room ATC B1110 15 10 45Coffee break 10 45 11 45Lecture EV characterization by transmission electron microscopy and western blot analysis Guillaume Van Niel Institute of Psychiatry and Neuroscience of Paris France Courtyard Room A B 11 45 12 00Intro to practical session Guillaume Van Niel Institute of Psychiatry and Neuroscience of Paris France Courtyard Room A B 12 00 12 45Group activity Tour of electron microscopy core facility with Q A session12 45 13 45Lunch breakEMBL Canteen13 45 17 15Practical sessions 5 6 7 in parallel with flexible coffee break Group 1 EM Prep Maribel Lara CoronaGroup 2 EM remote Guillaume Van NielGroup 3 EV Track An Hendrix Cl udio Pinheiro Sarah Deville virtual Training Lab A B EM Facility Courtyard Room A B Group 1 EM Prep Maribel Lara CoronaGroup 2 EM remote Guillaume Van NielGroup 3 EV Track An Hendrix Cl udio Pinheiro Sarah Deville virtual Training Lab A B EM Facility Courtyard Room A B Group 1 EM Prep Maribel Lara CoronaGroup 2 EM remote Guillaume Van NielGroup 3 EV Track An Hendrix Cl udio Pinheiro Sarah Deville virtual Training Lab A B EM Facility Courtyard Room A B 17 15 18 15Q A SessionCourtyard Room A B 18 15 19 00Pizza dinnerATC Foyer19 00 21 00Poster session II EVEN numbers with drinksATC Foyer21 00Bus from EMBL to ISG hotelEMBL bus stop Day 5 Thursday 16 March 2023 Time Europe Berlin SpeakerLocation08 40Bus from ISG hotel to EMBLISG hotel bus stop09 00 09 15Outline of the dayEsther Nolte t Hoen Utrecht University The Netherlands Courtyard Room A B 09 15 10 00Lecture Impact of pre analytical factors on EV separation Cecilia L sser University of Gothenburg Sweden Virtual Speaker Courtyard Room A B 10 00 11 15Practical 8 Data Analysis in 3 groups Trainers An Hendrix Esther Nolte t Hoen Ana s B cot Cl udio Pinheiro Estefania Lozano Andr s Maribel Lara Corona Guillaume Van NielCourtyard Room A B Flexlab A B Seminar room ATC B1111 15 11 45Coffee break11 45 12 45Practical 8 continuation Data Analysis in 3 groups Trainers An Hendrix Esther Nolte t Hoen Ana s B cot Cl udio Pinheiro Estefania Lozano Andr s Maribel Lara Corona Guillaume Van NielCourtyard Room A B Flexlab A B Seminar room ATC B1112 45 12 55Group photo12 55 13 45Lunch break EMBL Canteen13 45 15 45Practical 8 continuation Presentation data analysis and discussionCourtyard Room A B 15 45 16 15Coffee break16 15 17 00Lecture Functional EV analysis in vivoMichiel Pegtel Amsterdam UMC The NetherlandsCourtyard Room A B 17 00Bus from EMBL to ISG HotelEMBL bus stopFree evening Day 6 Friday 17 March 2023 Time Europe Berlin SpeakerLocation08 40Bus from ISG hotel to EMBLISG hotelbus stop09 00 09 15 Outline of the dayAn Hendrix Ghent University BelgiumCourtyard RoomA B 09 15 10 00Lecture TranscriptomicsCl udio Pinheiro Ghent University BelgiumCourtyard Room A B 10 00 10 45Lecture Separation of EVs from different biofluidsOlivier De Wever Ghent University BelgiumCourtyard Room A B 10 45 11 15Coffee break11 15 12 00Lecture ProteomicsSuresh Mathivanan La Trobe University AustraliaCourtyard Room A B 12 00 13 00Lunch breakEMBL Canteen13 00 15 30Practical 9 Practical BioinformaticsSuresh Mathivanan La Trobe University AustraliaComputer Training Lab15 30 16 00Coffee break16 00 16 45Lecture LipidomicsJohan Swinnen KU Leuven BelgiumCourtyard Room A B 16 45 17 30Lecture Clinical applicationMario Gimona Paracelsus Medical University AustriaCourtyard Room A B 17 30 18 30 Meet the speakers sessionCourtyard Room A B ATC Foyer 18 30 19 00Wrap up sessionCourtyard Room A B 19 00Bus from EMBL to Neckarm nzplatz via ISG Hotel EMBL bus stop19 45Course dinner downtown Practical information Registration fees and motivation letter The course is limited to 24 participants For selection purposes please note that your application will not be considered without a letter of motivation Registration Registration fees include admission course materials COVID 19 safety measures meals and coffee breaks This EMBO course includes accommodation and transportation to and from the ISG Hotel to the venue Academia 500PhD Student 500Industry 1000 NO visa support letters will be issued until payment of the registration fee is confirmed Confirmation and payment The registration fee should be paid only after acceptance to the course The results will be announced approximately 2 3 weeks after the application deadline Motivation letter submission After you have logged in and successfully registered you will receive an email asking you to submit your motivation letter Click on the link provided and enter your motivation letter in the text box provided Alternatively you can submit your motivation letter by clicking on the link on the confirmation page directly after registering Instructions Include your relevant skills experience and qualifications showing why you would be suitable for the course Explain why you would like to attend including what you can contribute and how you think you will benefit from the course Please note The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised For detailed instructions please watch our video on how to submit a course motivation letter Further details For further information about registration and motivation letter submission please refer to the FAQ page Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of both registration fee waivers and travel grants Availability is limited to participants attending on site EMBL Courses and virtual or on site EMBO Practical Courses in Heidelberg and will be indicated during the motivation letter submission process Your place in the course is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course Travel grant The travel grant will cover the cost of travel airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Course within Europe up to 1000 for participants travelling to an EMBL Course from outside Europe up to 500 for any participant travelling to an EMBO Practical Course up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Practical Course up to 700 for any participant working in Croatia Czech Republic Estonia Greece Hungary Italy Lithuania Luxembourg Poland Slovenia and Turkey travelling to an EMBO Practical Course Registration fees are only covered for EMBO Practical Courses The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant EMBO Practical Courses only For EMBO Practical Course participants with children there is the possibility to apply for a childcare grant to offset child care costs incurred by participants or speakers when participating at a course Eligible costs include fees for a babysitter or child care facility travel costs for a caregiver or travel costs for taking the child to the meeting etc Please note that priority will be given to early stage researchers A maximum amount of 500 can be awarded per participant applying for an EMBO childcare grant Boehringer Ingelheim Fonds travel grant Applies to selected courses only Availability will be indicated during the motivation letter submission process This grant covers costs related to your attendance at the course registration travel and accommodation costs The grant is restricted to PhD students and postdocs who conduct basic biomedical research Whether you are eligible to apply for a travel grant depends on when you received your university entrance qualification e g Abitur A Levels High School Diploma Final State Examination for PhD and MD students as well as graduates the university entrance qualification must not have been obtained more than 11 years ago at the time of the envisaged course for postdocs the university entrance qualification must not have been obtained more than 13 years ago at the time of the envisaged course Application You may apply for financial assistance when submitting your motivation letter for courses In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application For the Boehringer Ingelheim Fonds Travel Grant there is a pre application question during the motivation letter submission process and if selected you will be requested to complete a standard form and documentation consisting of your travel expense estimation Selection The scientific organisers will select the recipients of all financial assistance during the motivation letter selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the course Selection is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details See our list of external funding opportunities and for further information about financial assistance please refer to the FAQ page Accommodation and shuttles Hotel Accommodation has been pre booked for you at the ISG Hotel for the default dates of Sunday 12 March to Saturday 18 March 6 nights Please note that the course registration fee includes coverage of accommodation costs in twin rooms including breakfasts for your stay at the ISG In case you would like to have a single room please let us know and please note that you will be required to pay an additional cost of 31 per night This should be paid by you directly to the ISG during your stay Any additional nights need to be booked and paid for by you We recommend that all course participants stay at the ISG Hotel which is the dedicated hotel for the course Local transport Shuttle buses will go from the ISG Hotel to EMBL and back mornings and evenings A bus schedule and location of the bus stops will be made available prior to the meeting Further details Address EMBL Heidelberg Meyerhofstra e 1 69117 Heidelberg GermanyFor further information on getting to EMBL Heidelberg visit our Travel Information page For enquiries about accommodation and local transportation please refer to the FAQ page Technical requirements and event software Technical requirements Below you will find the software and technical requirements for this course Participants need to bring their own laptops which will be used to remotely access EMBL virtual machines with pre installed software You will need admin rights to install the software required to access the virtual machines If you do not have admin rights please contact your technical support team in advance to make sure the software can be installed If you have a non standard HDMI port other than type A you need to bring an adaptor Keyboard and PC mouse are available for use with a standard USB port If you have a different port type such as USB C you will need to bring your own Event software The EMBL eCampus learning platform will be used to collaborate communicate and network with all of the course participants All participants will receive information on how to join shortly before the course We recommend using Chrome Safari or Mozilla Firefox browsers for eCampus Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page COVID 19 related questions COVID 19 information for on site events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Event partners Event sponsors Event supporters Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information on sponsoring possibilities If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9...

An Hendrix, Cecilia Lässer, Esther Noltet Hoen, Guillaume Van Niel

EMBO Practical Course

EMBL Heidelberg

9 March 2023

Supercomputer-based modelling and simulation for advanced biomedical applications

Edit

March 09, 2023 15:002023WebinarVirtual

Description In this talk we will show advancements on the usage of supercomputer based modelling and simulation in advanced biomedical applications including tools for creating virtual populations of Virtual Human Twins and Twinoids In particular we will showcase computational achievements on coupled multi scale and multi physics problems to create in silico clinical trials to understand physiology and to improve old and create new and better therapies Regarding the application problems we will present contributions on blood circulatory system cardiac hemodynamics bioprosthetic heart valves implants and valve reparation surgical procedures respiratory fluid mechanics from upper airways down to alveoli inhalers and nebulizers lung models spinal intrathecal fluid mechanics etc About the speaker Mariano V zquez is CTO CSO of the company ELEM Biotech which develops and commercialises supercomputer based applications for the biomedical sector and researcher of the Barcelona Supercomputing Center from which ELEM spun off in 2018 He has a PhD from the Technical University of Catalunya UPC with postdocs in Dassault Aviation and in INRIA Sophia Antipolis in France...

Mariano Vázquez

Virtual

8 March 2023

Non-invasive phenotyping to quantify the dynamics of plant-environment interaction

Edit

March 08, 2023 15:302023WebinarVirtual

Description Genes provide a toolbox by which plants can interact with their spatially and temporally highly dynamic environment The environment of shoots and roots are distinctly different in their spatial and temporal structures State of the art phenotyping allows deep analysis of these interactions using imaging and even tomographic devices above and below ground This webinar will introduce the concept of plant environment interaction in different spatial and temporal domains and will describe some case studies with modern technologies to study these interactions It will also define the ESFRI Plant Phenotyping Research Infrastructure EMPHASIS and the opportunities for accessing these globally unique facilities for deep phenotyping as well as high throughput and field phenotyping...

Ulrich Schurr, Roland Pieruschka, Sven Fahrner

Virtual

8 March - 11 March 2023

The cellular mechanics of symbiosis

Edit

UniProt for proteomics scientists

Edit

March 02, 2023 15:002023WebinarVirtual

Description UniProt is a comprehensive expert led publicly available database of protein sequence function and variation information This webinar will give a brief introduction to the UniProt website and then highlight resources available that proteomics scientists or users with large protein datasets may find useful in analysing their data This will encompass our proteomes service how to convert and retrieve ID mappings how to carry out a peptide search and how to visualise new large scale proteomics derived PTM data The webinar will then go on to introduce the UniProt Proteins API which allows researchers to access and download UniProt data alongside large scale genomic proteomics and variation data without needing prior in depth knowledge of programmatic languages Data is available for download and querying in a range of formats including XML FASTA and PEFF The API multi query search functions will be demonstrated and useful features such as searching entries by peptide and the new functionality of searching for proteomic peptides and modifications will be explained The UniProt Proteins API is available at www ebi ac uk proteins api doc...

Emily Bowler-Barnett

Virtual

1 March 2023

Exploring plant genes and genomes with Ensembl

Edit

March 01, 2023 15:302023WebinarVirtual

Description The Ensembl Plants genome browser provides visualisation and analysis of integrated genomic data including genes variants comparative genomics and gene regulation for over 100 plant species and cultivars This webinar will provide an overview of the range of available data and through Ensembl Plants and use examples to explore the various interfaces for visualising and exporting data...

Guy Naamati

Virtual

1 March - 4 March 2023

2025 TEMPLATE_Symposium_Onsite_with_Virtual

Edit

March 01, 2023 00:002023ConferenceEMBL Heidelberg, Virtual

Description OverviewSpeakersProgrammePractical informationSponsorsAboutMedia kit Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Registration is not yet open for this event If you are interested in receiving more information please register your interest Symposium overview SHORT summary about the event and why delegates should attend could also be merged with the aims Please send final summary to marketing team for proofing before publishing Session topics Topic 1 Topic 2 Topic 3 Topic 4 Topic 5 Topic 6 What past participants say about the Symposium Quote Name affiliation Country only if applicable Speakers Keynote speakers Speakers Scientific organisers Conference organisers Programme Are you on social media Post using xxx Event hashtag and don t forget to tag EMBLEvents Please note that the programme is subject to change Some speakers may need to join virtually to give their talk For registered participants recorded talks will be accessible on demand for 4 weeks after the end of the event unless indicated otherwise Day 1 Day Month Year Day 2 Day Month Year Day 3 Day Month Year Day 4 Day Month Year Practical information Registration fees and abstract submission On site registration fees include admission conference materials meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Virtual registration fees include access to all of the talks livestreamed and on demand and facility to submit questions On site Academia XXXOn site PhD Student XXXOn site Industry XXXOn site Journal Editor XXXVirtual Academia XXXVirtual PhD Student XXXVirtual Industry XXX Editors from scientific journals are allowed to attend at a reduced rate but asked to contribute to the conference in return by taking part in meet the editors sessions or other planned activities within the programme A letter to support your visa application will be issued on request once payment of the registration fee is confirmed We recommend that you book your visa appointment as soon as possible to avoid any delay with your visa application Accredited journalists may be eligible to register for complimentary press registration Registrants may be required to provide accreditation or equivalent proof of press membership after registration Please contact Name of CO for more information Please note that we do not offer complimentary registrations for editors of scientific journals Confirmation and payment Registration will be on a first come first served basis Your place can only be confirmed after payment of the registration fee If you are added to our waiting list please consider taking advantage of our offerings to participate virtually On site participants Types of payments accepted are international bank transfers and credit card payments Virtual participants We are only able to accept card payments In exceptional cases we can accept bank transfers Please contact events embl de for details Abstract submission Only participants registering to attend the on site event are eligible to submit an abstract Abstracts will not be accepted from virtual participants After registration you can submit your abstract via a separate link that will be provided in the email confirmation Alternatively you can access the link on the confirmation page directly after registering The same login credentials are used for both processes Please note Abstract body The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised Title The title should not exceed 20 words Only the first word of the title should start with a capital letter and the rest should be lowercase Authors and affiliations Please fill in the author s details as requested in the online form The compulsory fields are First Name Last Name Organisation Name Affiliation or Company Country and Email Kindly mark only one author in the role of First Author and please don t forget to indicate who will be the Presenter Please enter your co authors correctly via the system by adding accounts together with their organisation institute Do not copy paste them into the body of the abstract text as they will not be indexed in the abstract book Presentation types When submitting your abstract you can apply for an oral or poster presentation A selection process will take place with the results announced 2 3 weeks after the abstract submission deadline For detailed instructions on how to submit a conference abstract follow the instructions provided in this video Please check our FAQs pages for further information on how to submit an abstract Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of registration fee waivers travel grants and childcare grants Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course or conference Travel grant The travel grant will cover the cost of travel to an on site event airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from within Europe up to 1000 for participants travelling to an EMBL Conference or EMBO EMBL Symposium from outside Europe up to 500 for any participant travelling to an EMBO Workshop up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Workshop up to 700 for any participant working in Croatia Czech Republic Estonia Greece Hungary Italy Lithuania Luxembourg Poland Slovenia and Turkey travelling to an EMBO Workshop Registration fees are only covered for EMBO Workshops The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant There is the possibility to apply for a childcare grant to offset child care costs incurred by participants speakers and organisers when attending a conference Eligible costs include but are not limited to fees for a baby sitter or child care facility and travel costs for a caregiver Please note that priority will be given to early stage researchers In order to apply for this grant you must be registered by the abstract submission deadline There is a limited amount of funding available for the childcare grants and funds will be distributed amongst eligible applicants Application On site participants You may apply for financial assistance when submitting your abstract In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Virtual participants If you are attending virtually you can apply for financial assistance in the submission portal by the abstract deadline Read the instructions on how to apply for financial assistance Only submissions for financial assistance will be accepted Presentation abstracts cannot be submitted here and will be declined In your application you will be asked to summarise your current work answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Selection The scientific organisers will select the recipients of all financial assistance during the abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection for registration fee waivers and travel grants is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Childcare grants will be allocated in the same timeframe 6 8 weeks before the event start date Please note that priority will be given to early stage researchers Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details View our list of external funding opportunities and information on attending a conference as an event reporter For further information about financial assistance please refer to the FAQ page Accommodation and travel Accommodation is not included in the conference registration fee As further changes in our events are possible you should book flights trains and hotels with flexible options and favourable cancellation conditions The hotels below have rooms on hold for participants until Day Month Year in some cases at special rates Please email the hotel directly quoting the booking code XXX20 to confirm the exact price of the room Hotel AnlageHotel ibis HeidelbergHotel MonptiHotel Bayrischer Hof InterCity Hotel HeidelbergPremier Inn Heidelberg CityB B HotelISG Hotel Staycity Aparthotel HeidelbergExzellenz HotelLeonardo Hotel Heidelberg City CentreSteffi s Hostel HeidelbergHilton HeidelbergMeininger HeidelbergHotel Vier Jahreszeiten HeidelbergHotel Holl nder Hof Travel information For travel information please see here If you are travelling to the conference within Germany then you are eligible for the Deutsche Bahn Event Ticket called the Veranstaltungsticket in German This will result in a lower ticket price if your travel distance to Heidelberg is more than 100 km You need to provide proof of your event attendance when purchasing the ticket For more information in English see here or in German see here You can book your ticket here Conference shuttle buses Conference shuttle buses are free of charge for participants and depart from designated bus stops near the hotels to EMBL and back mornings and evenings The bus stops for this conference are Hotel Staycity Speyerer Str 7 Kurf rsten Anlage Opposite Main Train Station Hotel Premier Kurf rsten Anlage 23 Leonardo Hotel Heidelberg City Center Bergheimer Str 63 Neckarmuenzplatz Heidelberg Tourist Information Peterskirche Bus stop ISG Hotel Im Eichwald 19 View Conference shuttle bus stops and hotels in a larger map Please note that not every bus stop will be used for every event Further details Address EMBL Meyerhofstra e 1 69117 Heidelberg Germany For more information about accommodation and travel please refer to the FAQ page Onsite information Catering All meals and coffee breaks are included in the registration fee Our catering staff will prepare a wide variety of vegetarian meals meat and fish dishes soups pasta fresh fruit and vegetables as well as a variety of desserts Please wear your badge at all times when serving yourself No food or drinks are allowed in the auditorium Charging lockers There are lockers available next to the stairs leading down into the Auditorium You will find some of those equipped with sockets to charge your smartphone tablet etc Electricity and charging station In most places the electricity is 220 volts AC 50 cycles An adaptor and a plug that fits the German socket may be needed for your appliances laptop i e American Japanese etc A USB charging station for electronic devices is available at the registration desk EMBL merchandise If you are interested in purchasing EMBL merchandise products presented in the glass display in the registration area please email the EMBL shop to place an order or get in contact with your Course Organiser Kindly note the EMBL shop is only open upon request and all purchases must be made in cash Euros only Health and safety notes Please read EMBL s COVID 19 safety policy for on site events Do not smoke in any EMBL building Eating and drinking is prohibited in the Auditorium and all laboratories Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required The first aid room is located next to the ATC Registration Desk room 10 205 Dial the Emergency number 222 from any EMBL internal phone only Where is the accident What happened How many injured Emergency number 06221 387 7821 from mobile phones Please report all accidents to the conference officer at the registration desk In case of fire Press the nearest fire alarm button or the Emergency number 222 from any internal phone A loud fire alarm will go off if an evacuation is required On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting points Do not use the lifts Beyond first aid Please remember to bring your own medication if needed to the conference Note that the next pharmacy is a 4 minute drive from the EMBL but for many medications you will be required to see a doctor to get a prescription Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg In any case the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary Internet Wi Fi is available on campus using the EMBL Events network and the event specific password which will be provided on site The eduroam network secure worldwide roaming access service developed for the international research and education community is also available Lost and found Lost and Found items are kept at the registration desk until the end of the conference Luggage There are lockers available on site to store your luggage which require a 2 EURO coin to operate There is another luggage room on level E0 which is free to use but remains unlocked during the conference Nursing room There is a nursing room available in the ATC Rooftop Lounge on level A29 Photography During the conference an EMBL Photographer may be taking photos If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Printing We can help to print your boarding pass train ticket Please send it to events embl de and collect your print outs at the registration desk Room for prayer yoga and meditation There is a room for prayer meditation and yoga located on level E0 behind the Auditorium Please be respectful of others using the room Sightseeing A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing Travel to and from the venue During the event we provide conference shuttle buses to and from EMBL In addition there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time Information on the conference shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page Useful German expressions HelloHalloGoodbyeAuf Wiedersehen formal Tsch ss informal Good morningGuten MorgenGood afternoonGuten TagGood eveningGuten AbendGood nightGute NachtI m sorryEs tut mir leidExcuse me Entschuldigen Sie How are you Wie gehts I m fine thanks And you Mir geht es gut danke Und dir Ihnen What is your nameWie hei en Sie formal Wie hei t du informal My name is Ich hei e Do you speak English Sprechen Sie Englisch I don t understandIch verstehe nichtPlease speak more slowlyK nnen Sie bitte langsamer sprechenThank youDankesch nWhere is the toilet Wo ist die Toilette Please call me a taxiBitte rufen Sie mir ein TaxiHow do I get to Wie komme ich zum zur A beer two beers pleaseEin Bier zwei Bier bitteA glass of red white wine pleaseEin Glas Rot Wei wein bitteThe menu pleaseDie Speisekarte bitteIs there a local speciality Gibt es eine Spezialit t aus dieser Gegend I m vegetarianIch bin VegetarierIt was deliciousEs war hervorragendThe bill pleaseDie Rechnung bitteI have a headacheIch habe KopfschmerzenI have a sore throatIch habe HalsschmerzenMy stomach hurtsIch habe MagenschmerzenI m allergic toIch bin allergisch gegenI need a doctor who speaks English Ich brauche einen Arzt der Englisch spricht Virtual participation What s included Access to all the livestreamed talks Video library of the recorded talks during the event and for 4 weeks afterwards Please note at the request of individual speakers some talks are not recorded Facility to submit questions Please note that only on site participants are able to submit abstracts and participate in the poster sessions Event platform We are using an event platform for this conference More information about the platform will be shared ahead of the conference Guidelines Do not broadcast the conference to unregistered participants You are encouraged to tweet and post about the event Tweet unless the speaker specifically says otherwise but be mindful of unpublished data Please do not capture transmit or redistribute data presented at the meeting Additional information can be found in our Code of Conduct Health and well being It is important to stay healthy and move around especially when you are attending an event virtually We have put together a few coffee break stretches and yoga videos in the conference platform for you to enjoy during the event How to ask questions Please use the Q A function in the event platform If you have any other questions you can go to the Help Desk in the event platform Click on more on the top menu and click Help Desk Time zone The programme is planned based on the Europe Berlin time zone unless otherwise stated Please take your time zone into consideration when planning your attendance Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for participants page COVID 19 related questions COVID 19 information for onsite events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de About EMBO EMBL Symposia promote scientific communication and collaboration in the European research area They provide scientists with a platform to discuss and exchange ideas on forward looking topics and new developments in the life sciences Topics emphasise upcoming developments and the interdisciplinary nature of related fields Jointly funded and organised by EMBO and EMBL and complementary to their respective courses workshops and conference programmes the symposia promote scientific communication and collaboration All symposia are held in the EMBL Advanced Training Centre ATC in Heidelberg Germany or virtually Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9 Leaderboard 728 90...

EMBO | EMBL Symposium

EMBL Heidelberg, Virtual

26 February - 3 March 2023

Analysis and integration of transcriptome and proteome data

Edit

February 26, 2023 00:002023CourseEMBL Heidelberg

Description OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview Please see EMBL s COVID 19 safety policy for testing and other requirements to attend this on site course Course overview Systems biology is a still expanding field of research aiming to understand at the molecular level how cells tissues and organisms operate in their biological context Among the key technologies driving this forward are next generation sequencing and proteomics as they provide powerful means to determine global expression levels of genes and proteins Both fields have matured to a degree that they have now become accessible to researchers in many areas of biology During this course participants will gain theoretical insight in the structure of sequencing and proteomic data and they will receive training in data analysis for the annotation quantification and statistical analysis of gene and protein expression using various computational tools In addition training will be provided in the use of Cytoscape to derive biological insights from the integration of both data types Audience This course is targeted at biologists and biochemists who are starting to be involved in both next generation sequencing and mass spectrometry based proteomics but who are not experts in these fields Modules resources Principles of mRNA quantification Principles of protein identification and quantification Principles and application of bioinformatic tools for mining of transcriptome and proteome data Data integration by Cytoscape Learning outcomes The aim of this practical course is to provide insight in techniques that are frequently used for transcriptome and proteome analysis and to provide hands on experience turning primary data into information that can be used for further biological interpretation To achieve these goals participants will gain insight in the basic principles of gene expression analysis RNAseq data quantification and differential expression analysis protein identification and quantification and they will be trained in the use of software tools to analyse sequencing and proteomic data SearchGUI PeptideShaker MaxQuant In addition the course will provide insight in the complementarity of transcriptome and proteome data by their integrative analysis via Cytoscape What past participants say about the course This course organised by EMBL is an excellent opportunity for wet lab biologists to gain skills and understand the necessary bioinformatic background for both designing experiments and performing data analysis Katarzyna Tutak Institute of Human Genetics Polish Academy of Science Speakers Speakers trainers and staff Vladimir Benes EMBL Heidelberg Germany Hyungwon Choi National University of Singapore Singapore Daria Fijalkowska Ghent University Belgium Jeroen Krijgsveld German Cancer Research Centre DKFZ Germany Manjeet Kumar EMBL Heidelberg Germany Jonathan Landry EMBL Heidelberg Germany Lennart Martens VIB University of Ghent Belgium Gerben Menschaert University of Ghent Belgium Scooter Morris University of California San Francisco USA Santhust EMBL Heidelberg Germany Mikhail Savitski EMBL Heidelberg Germany Jan Provaznik EMBL Heidelberg Germany Kristina Roucova Univerzita Karlova Czech Republic Scientific organisers Vladimir Benes EMBL Heidelberg Germany Raffaele Calogero University of Turin Italy Jeroen Krijgsveld German Cancer Research Centre DKFZ Germany Lennart Martens VIB University of Ghent Belgium Course organisers Maria Mercedes Bacadare Goitia Course and Conference Manager EMBL Heidelberg Germany Swetlana Krez Training Lab Technician EMBL Heidelberg Germany Programme Got something to say Tweet it EMBLDataIntegration Some pre course work such as watching pre recordings protocol reading and computational exercises with estimated time 0 10 hours will be required and will be shared in advance of the course Some speakers may need to join virtually to give their lecture or Q A and the programme is subject to change The preliminary programme below is a draft and is subject to change Day 1 Sunday 26 February 2023 Time Europe Berlin SpeakerLocation08 40 09 00Bus from ISG Hotel to EMBL ATC entranceISG Hotel bus stop09 00 09 15Arrival welcome and safety introductionsCourtyard room09 15 11 00RNA seq cool but is it that simple Vladimir Benes EMBL Heidelberg GermanyCourtyard room11 00 11 30Coffee breakATC Foyer11 30 12 30RNAseq Reads to genesJonathan Landry EMBL Heidelberg GermanyJan Provaznik EMBL Hiedleberg GermanyKristina Roucova Univerzita Karlova Czech RepublicCourtyard room12 30 13 30LunchEMBL Canteen13 30 16 00Practical From Reads to Genes Bulk and single cell Jonathan Landry EMBL Heidelberg GermanyJan Provaznik EMBL Hiedleberg GermanyKristina Roucova Univerzita Karlova Czech RepublicComputer Training Lab16 00 16 30Coffee breakComputer Training Lab16 30 18 00Q A on RNAseq and scRNAseqComputer Training Lab18 00Departure to ISG HotelATC entrance18 30DinnerISG Hotel Day 2 Monday 27 February 2023 Time Europe Berlin SpeakerLocation08 40 09 00Bus from ISG Hotel to EMBL ATC entranceISG Hotel bus stop09 00 10 00Flash talk presentationsComputer Training Lab10 00 12 30Practical theory Differential expression analysis Jonathan Landry EMBL Heidelberg GermanyJan Provaznik EMBL Hiedleberg GermanyKristina Roucova Univerzita Karlova Czech Republicwith flexible coffee breakComputer Training Lab12 30 13 30LunchEMBL Canteen13 30 16 00Practical session Ribosome profilingGerben Menschaert University of Ghent BelgiumComputer Training Lab16 00 16 30Coffee breakComputer Training Lab16 30 18 30Lecture practicals Ribosome profilingGerben Menschaert University of Ghent BelgiumComputer Training Lab18 30 19 40DinnerEMBL Canteen19 40Departure to ISG HotelATC entrance Day 3 Tuesday 28 February 2023 Time Europe Berlin SpeakerLocation08 40 09 00Bus from ISG Hotel to EMBL ATC entranceISG Hotel bus stop09 00 11 00Introduction to ProteomicsJeroen Krijgsveld German Cancer Research Centre DKFZ GermanyComputer Training Lab11 00 11 30Coffee breakComputer Training Lab11 30 12 30Lecture Quantitative proteomics TMTMikhail Savitski EMBL Heidelberg GermanyComputer Training Lab12 30 13 30LunchEMBL Canteen13 30 15 00Lecture Bioinformatics for proteomicsLennart Martens University of Ghent BelgiumComputer Training Lab15 00 16 00Practical Session Turning data into information peptide and protein identification database searchingLennart Martens University of Ghent BelgiumComputer Training Lab16 00 16 30Coffee BreakComputer Training Lab16 30 18 00Q A to Bioinformatics for proteomicsLennart Martens University of Ghent BelgiumComputer Training Lab18 00 19 00DinnerEMBL Canteen19 00Departure to ISG HotelATC entrance Day 4 Wednesday 1 March 2023 Time Europe Berlin SpeakerLocation08 40 09 00Bus from ISG Hotel to EMBL ATC entranceISG Hotel bus stop09 00 10 00Lecture Quantitative proteomics SILAC and other MS1 based approachesJeroen Krijgsveld German Cancer Research Centre DKFZ GermanyComputer Training Lab10 00 10 30Coffee break10 30 12 00Lecture Introduction to MaxQuant analysis of MS dataDaria Fijalkowska University of Ghent BelgiumComputer Training Lab12 00 13 00LunchEMBL Canteen13 00 14 30Practical Session Proteomics data interpretationDaria Fijalkowska University of Ghent BelgiumComputer Training Lab14 30 16 15Lecture P values and multiple testing correctionHyungwon Choi National University of Singapore SingaporeComputer Training Lab16 15 Free afternoon16 15Departure to ISG Hotel and downtown Day 5 Thursday 2 March 2023 Time Europe Berlin SpeakerLocation08 40 09 00Bus from ISG Hotel to EMBL ATC entranceISG Hotel bus stop09 00 10 00Q A to Bioinformatic tools for data comparison and integrationJohn Scooter Morris University of California San Francisco USAComputer Training Lab10 00 10 30Coffee break10 30 12 30Practical Introduction to CytoscapeJohn Scooter Morris University of California San Francisco USAManjeet Kumar EMBL Heidelberg GermanySanthust EMBL Heidelberg GermanyComputer Training Lab12 30 13 30LunchEMBL Canteen13 30 16 00Practical Introduction to CytoscapeJohn Scooter Morris University of California San Francisco USAManjeet Kumar EMBL Heidelberg GermanySanthust EMBL Heidelberg GermanyComputer Training Lab16 00 16 30Coffee breakComputer Training Lab16 30 17 45Lecture and Practical Enrichment analysisJohn Scooter Morris University of California San Francisco USAManjeet Kumar EMBL Heidelberg GermanySanthust EMBL Heidelberg GermanyComputer Training Lab17 45Departure to ISG Hotel and downtownATC entrance18 30Downtown Dinner Day 6 Friday 3 March 2023 Time Europe Berlin SpeakerLocation08 40 09 00Bus from ISG Hotel to EMBL ATC entranceISG Hotel bus stop09 00 10 00Application talk Network oriented integrative multi omics analysis of tissues and fluids case studies in cancer and cardiovascular diseasesHyungwon Choi National University of Singapore SingaporeComputer Training Lab10 00 10 30Coffee break10 00 12 30Practical Session Data integrationJohn Scooter Morris University of California San Francisco USAComputer Training Lab12 30 13 30LunchEMBL Canteen13 30 16 00Practical Session Data integrationJohn Scooter Morris University of California San Francisco USAManjeet Kumar EMBL Heidelberg GermanySanthust EMBL Heidelberg Germanywith flexible coffee breakComputer Training Lab16 00 16 30Course wrap up and farewellComputer Training Lab16 30Departure to Train Station and DowntownATC entrance Practical information Registration fees and motivation letter The course is limited to 24 participants For selection purposes please note that your application will not be considered without a letter of motivation Registration Registration fees include admission course materials COVID 19 safety measures meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Academia 690PhD Student 690Industry 1200 NO visa support letters will be issued until payment of the registration fee is confirmed Confirmation and payment The registration fee should be paid only after acceptance to the course The results will be announced approximately 2 3 weeks after the application deadline Motivation letter submission After you have logged in and successfully registered you will receive an email asking you to submit your motivation letter Click on the link provided and enter your motivation letter in the text box provided Alternatively you can submit your motivation letter by clicking on the link on the confirmation page directly after registering Instructions Include your relevant skills experience and qualifications showing why you would be suitable for the course Explain why you would like to attend including what you can contribute and how you think you will benefit from the course Please note The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised For detailed instructions please watch our video on how to submit a course motivation letter Further details For further information about registration and motivation letter submission please refer to the FAQ page Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of both registration fee waivers and travel grants Availability is limited to participants attending on site EMBL Courses and virtual or on site EMBO Practical Courses in Heidelberg and will be indicated during the motivation letter submission process Your place in the course is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course Travel grant The travel grant will cover the cost of travel airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Course within Europe up to 1000 for participants travelling to an EMBL Course from outside Europe up to 500 for any participant travelling to an EMBO Practical Course up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Practical Course up to 700 for any participant working in Croatia Czech Republic Estonia Greece Hungary Italy Lithuania Luxembourg Poland Slovenia and Turkey travelling to an EMBO Practical Course Registration fees are only covered for EMBO Practical Courses The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant EMBO Practical Courses only For EMBO Practical Course participants with children there is the possibility to apply for a childcare grant to offset child care costs incurred by participants or speakers when participating at a course Eligible costs include fees for a babysitter or child care facility travel costs for a caregiver or travel costs for taking the child to the meeting etc Please note that priority will be given to early stage researchers A maximum amount of 500 can be awarded per participant applying for an EMBO childcare grant Boehringer Ingelheim Fonds travel grant Applies to selected courses only Availability will be indicated during the motivation letter submission process This grant covers costs related to your attendance at the course registration travel and accommodation costs The grant is restricted to PhD students and postdocs who conduct basic biomedical research Whether you are eligible to apply for a travel grant depends on when you received your university entrance qualification e g Abitur A Levels High School Diploma Final State Examination for PhD and MD students as well as graduates the university entrance qualification must not have been obtained more than 11 years ago at the time of the envisaged course for postdocs the university entrance qualification must not have been obtained more than 13 years ago at the time of the envisaged course Application You may apply for financial assistance when submitting your motivation letter for courses In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application For the Boehringer Ingelheim Fonds Travel Grant there is a pre application question during the motivation letter submission process and if selected you will be requested to complete a standard form and documentation consisting of your travel expense estimation Selection The scientific organisers will select the recipients of all financial assistance during the motivation letter selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the course Selection is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details See our list of external funding opportunities and for further information about financial assistance please refer to the FAQ page Accommodation and shuttles Hotel Single rooms have been reserved for 6 nights 25 Feb 3 March 2023 at the ISG Hotel After the selection process selected participants should contact the hotel directly to make a booking booking code PRO23 01 We recommend that all course participants stay at the ISG Hotel which is the dedicated hotel for the course Local transport Shuttle buses will go from the ISG Hotel to EMBL and back mornings and evenings A bus schedule and location of the bus stops will be made available prior to the meeting Further details Address EMBL Heidelberg Meyerhofstra e 1 69117 Heidelberg GermanyFor further information on getting to EMBL Heidelberg visit our Travel Information page For enquiries about accommodation and local transportation please refer to the FAQ page Event software Event software The EMBL eCampus learning platform will be used to collaborate communicate and network with all of the course participants All participants will receive information on how to join shortly before the course We recommend using Chrome Safari or Mozilla Firefox browsers for eCampus Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page COVID 19 related questions COVID 19 information for on site events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other events or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9...

Vladimir Benes, Raffaele Calogero, Jeroen Krijgsveld, Lennart Martens

EMBL Course

EMBL Heidelberg

22 February 2023

Accessing variant data at the European Variation Archive

Edit

February 22, 2023 15:302023WebinarVirtual

Description The European Variation Archive EVA is a primary open repository for archiving accessioning and distributing genome variation including single nucleotide variants short insertions and deletions indels and larger structural variants SVs in any species This webinar will demonstrate how to access the latest EVA release consisting of submitted variants clustered into RS IDs It will also provide an overview of the recent updates to this data including what species have had their variant data remapped and how we annotate remapped variant data...

Baron Koylass

Virtual

22 February 2023

Interrogating the effect of enzyme kinetics on metabolism using differentiable constraint-based models

Edit

February 22, 2023 15:002023WebinarVirtual

Description Metabolic models are typically characterised by a large number of parameters Traditionally metabolic control analysis has been applied to differential equation based models to investigate the sensitivity of predictions to parameters A corresponding theory for constraint based metabolic models is lacking due to their formulation as optimization problems In this webinar we will show several applications of differentiating optimal solutions of constraint based models and show how it connects to classic metabolic control analysis Efficient differentiation of constraint based models can be used to calculate the sensitivities of predicted reaction fluxes and enzyme concentrations to turnover number parameters in an enzyme constrained metabolic model of Escherichia coli Further it unlocks the ability to use gradient information for parameter estimation We demonstrate this by improving genome wide the state of the art turnover number estimates for E coli Finally this technique can be used to differentiate the optimal solution of a model incorporating both thermodynamic and kinetic rate equations The predicted growth rate sensitivity to metabolite concentrations was shown to align well against experimentally measured metabolome changes subject to gene knockouts About the speaker St Elmo Wilken completed his undergraduate degree in Chemical Engineering at the University of Pretoria His Ph D at the University of California Santa Barbara leveraged both computational and wet lab aspects to investigate and understand the metabolism of anaerobic gut fungi His current postdoc at the Institute of Quantitative and Theoretical Biology at the Heinrich Heine University in D sseldorf is focused on using quantitative models to elucidate the contribution of metabolism to the stability and composition of microbial consortia He partnered with PerMedCoE researchers including Dr Miroslav Kratochvil to develop a way to differentiate constraint based models to conduct sensitivity analyses efficiently...

St. Elmo Wilken

Virtual

20 February - 24 February 2023

Introduction to RNA-seq and functional interpretation

Edit

February 20, 2023 00:002023CourseEMBL-EBI

Sophie Spencer

EMBL-EBI

12 February - 17 February 2023

In situ CLEM at room temperature and in cryo

Edit

February 12, 2023 00:002023CourseEMBL Heidelberg

Description OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview Course overview Correlative Light and Electron Microscopy CLEM allows precise localisation of an event of interest within cells and tissues During this course we will focus on a specific method that has been developed at EMBL that enables the localisation of fluorescent proteins with high accuracy at the ultrastructural level The course will cover both the theory and practicals of high precision CLEM as well as opportunities to discuss their research with CLEM experts and receive practical and troubleshooting advice Audience This course is intended for scientists with experience in EM who want to further develop their skills in high accuracy correlated microscopy Modules resources The course will combine lectures and hands on practical work covering all steps in the work flow including cryogenic sample preparation ultramicroscopy image registration and electron tomography Learning outcomes Participants will gain hands on experience with the CLEM methods and learn tips from the people who developed the methods Please see EMBL s COVID 19 safety policy for testing and other requirements to attend this on site course Speakers Speakers trainers and staff Ori Avinoam Weizmann Institute of Science Israel Johanna Bischof EMBL Heidelberg Germany Mandy B rmel EMBL Heidelberg Germany Petr Chlanda University of Heidelberg Germany Kar Ho Herman Fung EMBL Heidelberg Germany Helmut Gnaegi Diatome Ltd Switzerland Alexandra Elli ZEISS Research Microscopy Solutions Germany Martin Fritsch EMBL Heidelberg Germany Michael Hons EMBL Grenoble France Pedro Machado Oxford Instruments NanoAnalysis UK Julia Mahamid EMBL Heidelberg Germany Rachel Mellwig EMBL Heidelberg Germany Giulia Mizzon Heidelberg University Hospital Germany Viola Oorschot EMBL Heidelberg Germany Perrine Paul Gilloteaux University of Nantes France Virginia Pierini EMBL Heidelberg Germany Andreia Pinto Leica Microsystems Germany Paolo Ronchi EMBL Heidelberg Germany Anna Sartori Rupp Institut Pasteur France Martin Schorb EMBL Heidelberg Germany Christian Tischer EMBL Heidelberg Germany Zhengyi Yang EMBL Heidelberg Germany Ievgeniia Zagoriy EMBL Heidelberg Germany Scientific Organisers Ori Avinoam Weizmann Institute of Science Israel Rachel Mellwig EMBL Heidelberg Germany Martin Schorb EMBL Heidelberg Germany Course Organisers Lea Hohmann EMBL Heidelberg Germany Irena Provaznikova EMBL Heidelberg Germany Programme Got something to say Tweet it EMBOCLEM Some pre course work such as watching pre recordings protocol reading and computational exercises with estimated time 0 10 hours will be required and will be shared in advance of the course Some speakers may need to join virtually to give their lecture or Q A and the programme is subject to change Day 1 12 February 2023 Time Europe Berlin SpeakerLocation14 00 14 30RegistrationISG Hotel 14 30 15 00Welcome and house notes and course overviewISG Hotel 15 00 16 00EMBO Young Investigator Lecture How to choose your CLEM approach Ori Avinoam Weizmann Institute of Science IsraelISG Hotel 16 00 16 30Coffee breakISG Hotel 16 30 19 00Flash talks by speakers trainer and participantsISG Hotel 19 00 Open endDinnerISG Hotel Day 2 13 February 2023 Time Europe Berlin SpeakerLocation09 00 09 15Safety briefing Courtyard Room A B 09 15 10 15Keynote lecture History of Cryo CLEMAnna Sartori Rupp Institut Pasteur FranceCourtyard Room A B10 15 10 30Coffee breakCourtyard Room A B 10 30 11 30Lecture Strategies to culture cells for cryoEM Ievgeniia Zagoriy EMBL Heidelberg GermanyCourtyard Room A B11 30 12 15Lecture Technical aspects of the RT and Cryo CLEM workflowMandy Boermel EMBL Heidelberg Germany Martin Schorb EMBL Heidelberg GermanyCourtyard Room A B 12 15 13 15LunchATC Foyer13 15 18 30Practical Sample preparation RT and cryo parallel sessions for 3 sub groups Training Lab A B18 30 19 40DinnerEMBL Canteen Day 3 14 February 2023 Time Europe Berlin SpeakerLocation09 00 10 00Lecture Tips and tricks to adapt on section CLEM to diverse biological questionsPaolo Ronchi EMBL Heidelberg GermanyCourtyard Room A B 10 00 11 00Lecture Tricks and pitfalls in ultramicrotomyHelmut Gnaegi Diatome Ltd SwitzerlandCourtyard Room A B 11 00 11 15Coffee breakCourtyard Room A B 11 15 12 15Lecture Site Specific Cryo FIB PreparationJulia Mahamid EMBL Heidelberg GermanyCourtyard Room A B 12 15 13 00LunchEMBL Canteen13 00 19 00Practicals RT sectioning light microscopy at RT and cryo parallel sessions for 4 sub groups Training Lab A B19 00 20 00DinnerEMBL Canteen Day 4 15 February 2023 Time Europe Berlin SpeakerLocation09 00 10 15Computer practical SerialEM hands on with Remote TEM sessionMartin Schorb EMBL Heidelberg GermanyComputer Training Lab10 15 10 30Coffee breakComputer Training Lab10 30 12 00Computer practical SerialEM hands onMartin Schorb EMBL Heidelberg GermanyComputer Training Lab12 00 13 00LunchEMBL Canteen13 00 14 30Introduction Computer practical Icy and ec CLEM Perrine Paul Gilloteaux University of Nantes FranceComputer Training Lab14 30 15 00Coffee breakComputer Training Lab15 00 16 30Computer practical Icy and ec CLEMPerrine Paul Gilloteaux University of Nantes FranceComputer Training Lab16 30 17 00Wrap up of first round of practicals that have introduced the entire workflow Q AComputer Training Lab17 00 open endSocial Event Guided city tour and dinner in old town HeidelbergDowntown Heidelberg Day 5 16 February 2023 Time Europe Berlin SpeakerLocation09 00 10 00Keynote Lecture Cryo CLEM to study virusesPetr Chlanda University of Heidelberg GermanyCourtyard Room A B 10 00 10 30Coffee breakCourtyard Room A B 10 30 11 00Lecture Practical considerations for 3D cryo CLEMHerman Fung EMBL Heidelberg GermanyCourtyard Room A B 11 00 11 30Lecture EasyGrid Advancing cryo EM sample preparationMichael Hons EMBL Grenoble FranceCourtyard Room A B11 30 12 15Lecture Volume CLEM and 3DCLEMPedro Machado Oxford Instruments NanoAnalysis UKPaolo Ronchi EMBL Heidelberg GermanyCourtyard Room A B 12 15 13 00LunchEMBL Canteen13 00 19 00Practicals In depth PRACTICALS on specific topics based on students selection subgroups Training Lab A B 19 00 20 00DinnerEMBL Canteen Day 6 17 February 2023 Time Europe Berlin SpeakerLocation09 00 09 45Lecture Multimodal image data handling visualization etc Christian Tischer EMBL Heidelberg GermanyCourtyard Room A B 09 45 10 30Roundtable discussion on open questions students explain implementations for their own projectsCourtyard Room A B 10 30 11 00Coffee breakCourtyard Room A B 11 00 12 30Discussion Call for Help Discussion on specific questions concerning the participants projectsCourtyard Room A B 12 30 12 45Lecture Introduction to relevant networks EuroBioImaging access to imaging resources EMBL IC Aastha Mathur EMBL Heidelberg GermanyVirginia Pierini EMBL Heidelberg GermanyCourtyard Room A B 12 45 13 00Wrap up FeedbackCourtyard Room A B 13 00 13 15Packed lunch FarewellCourtyard Room A B Practical information Registration fees and motivation letter The course is limited to 20 participants For selection purposes please note that your application will not be considered without a letter of motivation Registration Registration fees include admission course materials COVID 19 safety measures meals and coffee breaks This EMBO course includes accommodation and transportation to and from the ISG Hotel to the venue Academia 500PhD Student 500Industry 1200 NO visa support letters will be issued until payment of the registration fee is confirmed Confirmation and payment The registration fee should be paid only after acceptance to the course The results will be announced approximately 2 3 weeks after the application deadline Motivation letter submission After you have logged in and successfully registered you will receive an email asking you to submit your motivation letter Click on the link provided and enter your motivation letter in the text box provided Alternatively you can submit your motivation letter by clicking on the link on the confirmation page directly after registering Instructions Include your relevant skills experience and qualifications showing why you would be suitable for the course Explain why you would like to attend including what you can contribute and how you think you will benefit from the course Please note The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised For detailed instructions please watch our video on how to submit a course motivation letter Further details For further information about registration and motivation letter submission please refer to the FAQ page Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of both registration fee waivers and travel grants Availability is limited to participants attending on site EMBL Courses and virtual or on site EMBO Practical Courses in Heidelberg and will be indicated during the motivation letter submission process Your place in the course is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course Travel grant The travel grant will cover the cost of travel airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Course within Europe up to 1000 for participants travelling to an EMBL Course from outside Europe up to 500 for any participant travelling to an EMBO Practical Course up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Practical Course up to 700 for any participant working in Croatia Czech Republic Estonia Greece Hungary Italy Lithuania Luxembourg Poland Slovenia and Turkey travelling to an EMBO Practical Course Registration fees are only covered for EMBO Practical Courses The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant EMBO Practical Courses only For EMBO Practical Course participants with children there is the possibility to apply for a childcare grant to offset child care costs incurred by participants or speakers when participating at a course Eligible costs include fees for a babysitter or child care facility travel costs for a caregiver or travel costs for taking the child to the meeting etc Please note that priority will be given to early stage researchers A maximum amount of 500 can be awarded per participant applying for an EMBO childcare grant Boehringer Ingelheim Fonds travel grant Applies to selected courses only Availability will be indicated during the motivation letter submission process This grant covers costs related to your attendance at the course registration travel and accommodation costs The grant is restricted to PhD students and postdocs who conduct basic biomedical research Whether you are eligible to apply for a travel grant depends on when you received your university entrance qualification e g Abitur A Levels High School Diploma Final State Examination for PhD and MD students as well as graduates the university entrance qualification must not have been obtained more than 11 years ago at the time of the envisaged course for postdocs the university entrance qualification must not have been obtained more than 13 years ago at the time of the envisaged course Application You may apply for financial assistance when submitting your motivation letter for courses In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application For the Boehringer Ingelheim Fonds Travel Grant there is a pre application question during the motivation letter submission process and if selected you will be requested to complete a standard form and documentation consisting of your travel expense estimation Selection The scientific organisers will select the recipients of all financial assistance during the motivation letter selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the course Selection is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details See our list of external funding opportunities and for further information about financial assistance please refer to the FAQ page Accommodation and shuttles Hotel Accommodation has been pre booked for you at the ISG Hotel for the default dates of 12 to 17 February 5 nights Please note that the course registration fee includes coverage of accommodation costs in twin rooms including breakfasts for your stay at the ISG In case you would like to have a single room please let us know and please note that you will be required to pay an additional cost of 31 per night This should be paid by you directly to the ISG during your stay Any additional nights need to be booked and paid for by you We recommend that all course participants stay at the ISG Hotel which is the dedicated hotel for the course Local transport Shuttle buses will go from the ISG Hotel to EMBL and back mornings and evenings The bus schedule can be found here Further details Address EMBL Heidelberg Meyerhofstra e 1 69117 Heidelberg GermanyFor further information on getting to EMBL Heidelberg visit our Travel Information page For enquiries about accommodation and local transportation please refer to the FAQ page Technical requirements and event software Event software The EMBL eCampus learning platform will be used to collaborate communicate and network with all of the course participants All participants will receive information on how to join shortly before the course We recommend using Chrome Safari or Mozilla Firefox browsers for eCampus Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page COVID 19 related questions COVID 19 information for on site events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Event supporter Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other events or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9...

Ori Avinoam, Rachel Mellwig, Martin Schorb

EMBO Practical Course

EMBL Heidelberg

10 February 2023

Accessing human disease and protein variant information in UniProtKB

Edit

February 10, 2023 15:002023WebinarVirtual

Description UniProt knowledgebase UniProtKB supports biomedical research by providing a comprehensive high quality and freely accessible resource of protein sequence and functional information This webinar will provide an overview on how to access human disease and protein variant information available in UniProtKB The annotation of protein molecular function involvement in human disease as well as disease associated variant positions variant characterisation and their impact on protein structure and function will be outlined Protein variant information will be presented in tabular view or in the feature viewer and shown how the feature viewer facilitates visualising the impact of variants on protein features and 3D structure Cross links to human specific databases and other relevant resources will be briefly discussed In addition it will be demonstrated how to access and download human variation datasets available in UniProtKB We hope that this introduction will give you an understanding of how to access disease related protein data in UniProtKB and how to make use of the different protein molecular data to analyse protein variant impact on protein function and structure...

Yvonne Lussi

Virtual

9 February 2023

The case of data reuse: ethical, legal, and societal issues in international genomic data access and sharing

Edit

February 09, 2023 14:002023WebinarVirtual

Description Health data collected in cohort studies are valuable sources for knowledge generation and the advance of biomedical research However the use of these data for research projects beyond the initial purpose raises several ethical legal and societal questions regarding the sensitivity of genomic data sourced from vulnerable and ethnic groups such as African genetic data and material The webinar addresses these challenges regarding reuse of health genomic data in CINECA from the ELSI perspective and FAIR principles and highlights GDPR provisions and their institutional sources of interpretation national laws the corresponding legal ethical and social science literature as well as outcomes from stakeholder engagement workshops with patient representatives African researchers and CINECA technical experts The webinar provides ethical and legal recommendations that take societal implications into account for data access to European Canadian and African cohorts and responsible sharing mainly on four key areas 1 Engagement and benefit sharing as prerequisites for data sharing 2 Informed consent and reuse of data 3 Safeguards and respect for privacy and 4 Further uses and data access The webinar concludes with an outlook on upcoming ELSI developments regarding data reuse synthetic data and artificial intelligence AI...

Melanie Goisauf, Emmanuelle Rial-Sebbag

Virtual

8 February - 11 February 2023

In situ structural biology: from cryo-EM to multi-scale modelling

Edit

Edit

January 24, 2023 00:002023CourseEMBL Heidelberg

Description OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview Please see EMBL s COVID 19 safety policy for testing and other requirements to attend this on site course Course overview The missing step between data collection and research progress is a lack of training for researchers in crucial skills for effectively managing and analysing large amounts of data This hands on workshop teaches researchers the fundamental data skills they need to conduct their work and provides high quality domain specific training covering the full lifecycle of data driven research The domain specific approach allows participants to tailor the data content and tools to reflect the specific data and analysis needs of different areas Audience The course is aimed at graduate students and other researchers in the life sciences who would like to learn good practices in project and data organisation and computational data analysis with R The course is ideally suited to students without prior experience in computational research but some familiarity with working with tabular data on a computer is welcome Modules resources Data organisation and cleaning Versioning with Git Introduction to R Data analysis and visualisation in R Data analysis with applications to genomics Learning outcomes How to organise data and some practices for more effective data handling To effectively clean and format data and automatically track any changes To use R to handle filter and summarise tabular data To use the split apply combine concept for data analysis To visualise the results of these analyses in R using the ggplot2 library To apply all of the concepts in an exploratory analysis of a typical biological dataset What past participants say about the course The best course to take first steps in data analysis I learned a lot and wholeheartedly recommend it to everyone learning programming for scientific purposes Magdalena Ziemianska Maj Institute of Pharmacology Polish Academy of Sciences Poland I have to thank all the instructors and organisers that made this course a success Very intuitive and everyone was very helpful leaving no doubts unanswered I highly recommend this course to anyone who wants to start learning R Soraia Vieira University of vora Portugal Speakers Speakers trainers and staff Renato Alves EMBL Heidelberg Germany Gaurav Diwan University of Heidelberg Germany Florian Huber EMBL Heidelberg Germany Lisanna Paladin EMBL Heidelberg Germany Fotis Psomopoulos Center for Research and Technology Hellas CERTH Greece Supriya Khedkar EMBL Heidelberg Germany Eleonora Mastrorilli EMBL Heidelberg Germany Scientific organisers Renato Alves EMBL Heidelberg Germany Lisanna Paladin EMBL Heidelberg Germany Fotis Psomopoulos Center for Research and Technology Hellas CERTH Greece Christian Schudoma EMBL Heidelberg Germany Course organisers Inna B sselmann Course and Conference Manager EMBL Heidelberg Germany Swetlana Krez Training Lab Technician EMBL Heidelberg Germany Programme Got something to say Tweet it with EMBLDataCarpentry On Monday 16 January at 11 am CET participants will be required to attend a virtual onboarding and software installation check via eCampus The course will continue on site on Tuesday 24 January and finish on Friday 27 January following the regular programme Participants need to bring their own laptops They will be requested to install software at a later stage Day 1 Tuesday 24 January 2023 Time Europe Berlin SpeakerLocation08 40Shuttle bus from ISG Hotel to EMBLISG Hotel entrance09 00 09 30Arrival welcome course overview and safety briefingCourtyard room A B09 30 10 30Flash talks and setup checkLisanna Paladin EMBL Heidelberg GermanyCourtyard room A B10 30 11 00Coffee BreakCourtyard foyer11 00 12 30Data Organization in SpreadsheetsLisanna Paladin EMBL Heidelberg GermanyCourtyard room A B12 30 13 30Lunch breakEMBL Canteen13 30 15 00OpenRefine for Data Cleaning Social NetworkingLisanna Paladin EMBL Heidelberg GermanyCourtyard room A B15 00 15 30 Coffee Break Courtyard foyer 15 30 17 30OpenRefine for Data Cleaning Social Networking Lisanna Paladin EMBL Heidelberg GermanyCourtyard room A B 17 30 18 30DinnerEMBL Canteen18 45Shuttle bus to ISG HotelATC entrance Day 2 Wednesday 25 January 2023 Time Europe Berlin SpeakerLocation08 40Shuttle bus from ISG Hotel to EMBL ISG Hotel entrance 09 00 11 00Versioning with GitRenato Alves EMBL Heidelberg Germany Courtyard Room A B 11 00 11 30Coffee Break Courtyard foyer 11 30 12 30Versioning with GitRenato Alves EMBL Heidelberg GermanyCourtyard Room A B 12 30 13 30Lunch breakEMBL Canteen13 30 15 00Introduction to RGaurav Diwan University of Heidelberg Germany Courtyard Room A B 15 00 15 30Coffee Break Courtyard foyer 15 30 18 00Introduction to RGaurav Diwan University of Heidelberg GermanyCourtyard Room A B 18 00 19 00DinnerEMBL Canteen19 00 Shuttle bus to ISG Hotel ATC entrance Day 3 Thursday 26 January 2023 Time Europe Berlin SpeakerLocation08 40Shuttle bus from ISG Hotel to EMBL ISG Hotel entrance 09 00 10 30Data manipulation with dplyrSupriya Khedkar EMBL Heidelberg Germany Courtyard room A B 10 30 11 00Coffee Break Courtyard Foyer 11 00 12 30Data manipulation with dplyrSupriya Khedkar EMBL Heidelberg GermanyCourtyard room A B 12 30 13 30Group photo and lunch breakEMBL Canteen13 30 17 00Data visualisation with ggplot2Eleonora Mastrorilli EMBL Heidelberg GermanyCourtyard room A B 15 00 15 30Coffee Break Courtyard foyer 15 30 17 30Data visualisation with ggplot2Eleonora Mastrorilli EMBL Heidelberg Germany Courtyard room A B 17 45Shuttle bus to downtownATC entrance18 30Social Course Dinner Downtown Day 4 Friday 27 January 2023 Time Europe Berlin SpeakerLocation08 40 Shuttle bus from ISG Hotel to EMBL ISG Hotel entrance 09 00 10 30Data analysis with applications to genomicsFotis Psomopoulos Center for Research and Technology Hellas CERTH GreeceCourtyard room A B 10 30 11 00Coffee BreakCourtyard foyer 11 00 12 30Data analysis with applications to genomicsFotis Psomopoulos Center for Research and Technology Hellas CERTH GreeceCourtyard room A B 12 30 13 30Lunch breakEMBL Canteen13 30 15 00Data analysis with applications to genomicsFlorian Huber EMBL Heidelberg GermanyCourtyard room A B 15 00 15 30Coffee BreakCourtyard foyer 15 30 17 00Data analysis with applications to genomicsFlorian Huber EMBL Heidelberg GermanyCourtyard room A B 17 00 17 30Debrief and wrap upCourtyard room A B 17 45Shuttle bus to Heidelberg main train station ATC entrance Practical information Registration fees and motivation letter The course is limited to 28 participants For selection purposes please note that your application will not be considered without a letter of motivation Registration Registration fees include admission course materials COVID 19 safety measures meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Academia 320PhD Student 320Industry 530 NO visa support letters will be issued until payment of the registration fee is confirmed Confirmation and payment The registration fee should be paid only after acceptance to the course The results will be announced approximately 2 3 weeks after the application deadline Motivation letter submission After you have logged in and successfully registered you will receive an email asking you to submit your motivation letter Click on the link provided and enter your motivation letter in the text box provided Alternatively you can submit your motivation letter by clicking on the link on the confirmation page directly after registering Instructions Include your relevant skills experience and qualifications showing why you would be suitable for the course Explain why you would like to attend including what you can contribute and how you think you will benefit from the course Please note The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised For detailed instructions please watch our video on how to submit a course motivation letter Further details For further information about registration and motivation letter submission please refer to the FAQ page Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of both registration fee waivers and travel grants Availability is limited to participants attending on site EMBL Courses and virtual or on site EMBO Practical Courses in Heidelberg and will be indicated during the motivation letter submission process Your place in the course is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course Travel grant The travel grant will cover the cost of travel airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Course within Europe up to 1000 for participants travelling to an EMBL Course from outside Europe up to 500 for any participant travelling to an EMBO Practical Course up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Practical Course up to 700 for any participant working in Croatia Czech Republic Estonia Greece Hungary Italy Lithuania Luxembourg Poland Slovenia and Turkey travelling to an EMBO Practical Course Registration fees are only covered for EMBO Practical Courses The organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant EMBO Practical Courses only For EMBO Practical Course participants with children there is the possibility to apply for a childcare grant to offset child care costs incurred by participants or speakers when participating at a course Eligible costs include fees for a babysitter or child care facility travel costs for a caregiver or travel costs for taking the child to the meeting etc Please note that priority will be given to early stage researchers A maximum amount of 500 can be awarded per participant applying for an EMBO childcare grant Application You may apply for financial assistance when submitting your motivation letter for courses In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application For the Boehringer Ingelheim Fonds Travel Grant there is a pre application question during the motivation letter submission process and if selected you will be requested to complete a standard form and documentation consisting of your travel expense estimation Selection The scientific organisers will select the recipients of all financial assistance during the motivation letter selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the course Selection is based on scientific merit your current work or study location the reasons for needing financial support and the impact this event will have on your career Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details See our list of external funding opportunities and for further information about financial assistance please refer to the FAQ page Accommodation and shuttles HotelHotel rooms have been reserved for 4 nights 23 27 January 2023 at the ISG Hotel After the selection process selected participants should contact the hotel directly to make a booking booking code DTC23 01 We recommend that all course participants stay at the ISG Hotel which is the dedicated hotel for the course Local transport Shuttle buses will go from the ISG Hotel to EMBL and back mornings and evenings The bus schedule can be found here Further details Address EMBL Heidelberg Meyerhofstra e 1 69117 Heidelberg GermanyFor further information on getting to EMBL Heidelberg visit our Travel Information page For enquiries about accommodation and local transportation please refer to the FAQ page Technical requirements and event software Technical requirements Below you will find the software and technical requirements for this course Please bring your own laptop You will be requested to install software at a later stage for which you will need admin rights on your laptop Event software The EMBL eCampus learning platform will be used to collaborate communicate and network with all of the course participants All participants will receive information on how to join shortly before the course We recommend using Chrome Safari or Mozilla Firefox browsers for eCampus Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page COVID 19 related questions COVID 19 information for on site events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other events or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsorship embl de Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9...

Renato Alves, Lisanna Paladin, Fotis Psomopoulos, Christian Schudoma

EMBL Course

EMBL Heidelberg

18 January 2023

Introduction to EMBL-EBI for teachers and trainers

Edit

January 18, 2023 15:302023WebinarVirtual

Description EMBL EBI is the home of the world s most comprehensive range of freely available molecular databases and resources Our resources help researchers share and analyse data and perform complex queries in many different ways EMBL EBI also provides open access on demand training materials which are usable by teachers lecturers or trainers for teaching bioinformatics methods and tools During this webinar we will provide an overview of the range of EMBL EBI data resources and the role of EMBL EBI in making data open and accessible and an introduction to the training and materials EMBL EBI provides We will finish the webinar with a panel discussion to highlight the support for teachers that EMBL EBI Training provides which includes a large variety of free to access training material content This will help you identify specific topics in bioinformatics or EMBL EBI databases and tools the on demand training available and how you can access and adapt the training materials in your own teaching session Meet the panel Anna Swan Anna is a scientific training officer for e Learning at EMBL EBI She has a PhD in Bioinformatics from the University of Nottingham where she focused on the bioinformatic identification of biomarkers of osteoarthritis Following her PhD Anna worked as a medical writer spanning many therapeutic areas and working both on promotional and educational content for clinicians She has also worked as a data wrangler for the International Mouse Phenotyping Consortium at the project s data coordination centre based in the Medical Research Council s Harwell Institute Benjamin Moore Ben is Ensembl outreach manager and he organises workshops and other training events for Ensembl resources Ben has a PhD in Biological Sciences from the MRC Laboratory of Molecular Biology at the University of Cambridge Summer Rosonovski Summer is a Community Outreach Officer for Europe PMC an open literature database for life sciences developed by the European Bioinformatics Institute EMBL EBI Europe PMC indexes over 300 000 preprints abstracts and full text COVID 19 preprints from 20 life sciences preprint servers alongside published journal articles Before joining Europe PMC Summer obtained a PhD in Biophysics from The University of East Anglia investigating the alternative DNA structure the i motif Summer is passionate about accessibility in science believing that everyone should have access to research results and have the tools and training to understand scientific literature...

Anna Swan, Benjamin Moore, Summer Rosonovski

Virtual

15 December 2022

Introducing PerMedCoE Building Blocks and Workflows to streamline biological analysis pipelines

Edit

December 15, 2022 14:002022WebinarVirtual

Description Analysing biological datasets is nearly always a multi step process involving many interconnected stages Even so the lack of transparent approaches to managing complex data analysis pipelines remains a common challenge in the life sciences Another limiting factor is that completing such pipelines often requires in depth knowledge of many data analysis tools and programming languages There is therefore a continued need for methodologies that make complex biological data analysis pipelines easier to implement This webinar will present some of the main practical ways through which PerMedCoE seeks to make data analysis pipelines more manageable and accessible to researchers In particular the webinar will provide an overview of how the project addresses many biological use cases using a single shared approach in which semi automated workflows are constructed using purpose designed building blocks About the speaker Dr Jesse Harrison is a Senior Data Scientist and Project Manager at CSC IT Center for Science Ltd where he currently leads the Horizon EU BioDT project His other tasks have included R environment design maintenance and support on CSC computing platforms bioinformatics tool development and teaching Prior to joining CSC in 2019 Jesse held postdoctoral positions in microbial ecology astrobiology and environmental chemistry at the universities of Helsinki Turku Vienna and Edinburgh 2012 2019...

Jesse Harrison

Virtual

14 December 2022

Exploring somatic mutations in cancer with the COSMIC database and analysis tools

Edit

December 14, 2022 15:302022WebinarVirtual

Description COSMIC the Catalogue of Somatic Mutations in Cancer helps the global cancer research community conduct their science faster and better by presenting easy to understand streamlined and quality filtered data on cancer mutations We do this by providing high quality datasets curated by experts over the course of 18 years standardising our data into easily integrable formats and innovating with collaborators to provide analysis tools and actionable insights With 23 million genomic variants expertly curated from nearly 30 000 publications covering 6 800 precise forms of human cancer COSMIC is the world s largest manually curated database of somatic mutation information relating to human cancers This vast breadth and depth of high quality data is the gold standard relied upon by academic research and industry alike including pharmaceutical drug discovery and biotech companies This webinar will provide an introduction to COSMIC our process and demonstrate the vast range of data and analyses available via our multiple tools and projects We will focus particularly on two of our newer projects Cancer Mutation Census and Actionability which will be freely available for non commercial download as of 29 November 2022 We will also provide an opportunity for questions and hope that by the end of the webinar you will feel confident in exploring COSMIC s tools and understand how they can add value to your work...

Rebecca White, Steven Jupe, Jennifer Wilding, Michael Starkey, Helder Pedro

Virtual

8 December 2022

Automated annotation in UniProt

Edit

December 08, 2022 15:002022WebinarVirtual

Pedro Raposo, Elena Speretta

Virtual

7 December 2022

Chemical biology Q&A session

Edit

December 07, 2022 15:302022WebinarVirtual

Description This Q A question and answer webinar will provide an opportunity for anyone who has completed Chemical biology A curated set of EMBL EBI online courses to join some of EMBL EBI s experts and ask their own questions This session will focus on exploring chemical compounds or drug molecules finding drug targets and target disease associations using resources such as ChEMBL and Open Targets The questions covered during the Q A webinar will depend on those asked by attendees however we will likely cover topics such as Curation and maintenance of chemical compounds database Chemogenomics Finding data about interactions between drugs or drug like molecules and their targets Drug discovery and target identification...

Virtual

7 December - 9 December 2022

The spectra of life: dimensional breadth in biological research

Edit

December 07, 2022 00:002022ConferenceEMBL Heidelberg, Virtual

Description...

2022 EMBL PhD Symposium Organising Committee

24th EMBL PhD Symposium

EMBL Heidelberg, Virtual

30 November 2022

Biocuration Q&A session

Edit

November 30, 2022 15:302022WebinarVirtual

Description This Q A question and answer webinar will provide an opportunity for anyone who has completed Biocuration A curated set of EMBL EBI online courses to join some of EMBL EBI s experts and ask their own questions This session will focus on the role of biocuration in maintaining life science data and general data management It will also highlight the application of programming and text mining in biocuration The questions covered during the Q A webinar will depend on those asked by attendees however we will likely cover topics such as Biocuration principles Data management of biological data and open data Programming and text mining for biocurators Finding the right EMBL EBI resource for accessing or submitting data...

Virtual

29 November - 2 December 2022

Protein quality control for downstream processes

Edit

November 29, 2022 00:002022CourseEMBL Heidelberg

Description OverviewSpeakers ProgrammePractical informationSponsorsMedia kit Overview Please see EMBL s COVID 19 safety policy for testing and other requirements to attend this on site course Course overview Purified proteins are used in various types of scientific experiments and fields For example in structural biology insights into the functional mechanisms can be obtained by elucidating the 3D molecular structure of proteins and protein complexes using technologies such as X ray crystallography cryo EM and NMR In biochemistry and biophysics interactions with other proteins nucleic acids and small molecules can be studied by determining affinities and specificities Proteins can function as antigens to generate specific antibodies or as reagents in cell biology experiments Furthermore recombinant proteins can be used as tool molecules in genomics chemical biology and microscopy assays In order for these experiments to produce reliable and biologically relevant results they must be performed using high quality proteins that are active properly folded in the right oligomeric state and contain correctly inserted co factors Ensuring that these parameters are fulfilled requires quality control In this course we want to help the participants to become acquainted with the concept of protein quality control and provide them with an overview of the specific protein requirements for various downstream applications Different techniques that can be applied for this purpose will be introduced and participants will have the opportunity to get hands on experience with these technologies Audience This course is aimed at life science researchers of all levels who are using or plan to use purified proteins in their wet lab experiments but who do not necessarily have a strong background in protein production and characterisation methods We will focus on introducing protein quality control methodologies in order to improve the reliability and reproducibility of data obtained from experiments that make use of purified proteins After this course participants should be familiar with the biochemical and biophysical techniques that can be applied to ensure that they are working with high quality protein samples suitable for the planned downstream experiments Modules resources Isothermal Titration Calorimetry ITC and Dynamic Light Scattering DLS Nano Differential Scanning Fluorimetry nano DSF and MicroScale Thermophoresis MST Size Exclusion Chromatography coupled to Multi Angle Light Scattering and Dynamic Light Scattering SEC MALS DLS and Mass PhotometryCryo Electron Microscopy cryo EM Learning outcomes During the course specialists from both academia and industry will work closely together to introduce technologies frequently used in protein quality control Some of these methodologies can be utilised both to assess protein quality and as stand alone biophysical characterisation techniques One of the highlights of the course that we are very excited about is the cryo electron microscopy cryo EM practical Cryo EM has undergone a revolution in recent years and is becoming increasingly popular in many interdisciplinary projects However in order to attain high resolution data the protein samples need to fulfil quite stringent conditions Our main goals are Teach the participants how to perform proper protein quality control checksIntroduce the participants to various biophysical techniques used for protein characterisation such as SEC MALS DLS mass photometry nano DSF spectroscopy and mass spectrometryShow participants how to characterise protein interactions using ITC and MSTProvide participants with a basic background on cryo EM and show the effects sample quality has on the acquired dataWhere possible allow participants to apply these technologies onto their own protein samples in the practicalsOverall increase the success rate reliability and reproducibility of downstream experiments in which purified proteins are used Speakers Speakers trainers and staff Inessa De BASF Germany Melisse Erasmus Refeyn UK Sebastian Eustermann EMBL Heidelberg Germany Simon Fromm EMBL Heidelberg Germany Maria Garcia Alai EMBL Hamburg Germany Pravin Kumar Ankush Jagtap EMBL Heidelberg Germany Sebastian Joecks Refeyn UK Arpita Kundu NanoTemper Germany Karine Valerie Lapouge EMBL Heidelberg Germany Andr Matagne Universit de Li ge Belgium Melanie McDowell Max Planck Institute of Biophysics Germany Bertrand Raynal Institut Pasteur France Kim Remans EMBL Heidelberg Germany Mandy Rettel EMBL Heidelberg Germany Agatha Rosenthal Malvern Panalytical Germany Jan Schnatwinkel NanoTemper Germany Christian Sieg Wyatt Germany Bernd Tartsch Malvern Panalytical Germany Scientific organisers Karine Valerie Lapouge EMBL Heidelberg Germany Kim Remans EMBL Heidelberg Germany Course organisers Lea Hohmann Course and Conference Manager EMBL Heidelberg Germany Swetlana Krez Training Lab Technician EMBL Heidelberg Germany Programme Got something to say Tweet it with EMBLProteinQC Some speakers may need to join virtually to give their lecture or Q A and the programme is subject to change Day 1 Tuesday 29 November 2022 Time Europe Berlin SessionLocation08 40 09 00Bus from hotel to EMBL ATC EntranceISG Hotel09 00 09 45Welcome and house notes and course overviewFlex Lab A B09 45 10 45Flash talks 5min Introduction round and Challenges and Expectations Flex Lab A B10 45 11 15Coffee BreakFlex Lab A B11 15 12 15Flash talks 5min Introduction round and Challenges and Expectations cont Flex Lab A B12 15 13 30LunchCanteen13 30 14 15Lecture An overview of protein expression and purification methods for obtaining high quality protein samplesKim Remans EMBL Heidelberg GermanyFlex Lab A B14 15 15 00Lecture An overview of Protein quality control The example of Institut PasteurBertrand Raynal Institut Pasteur FranceFlex Lab A B15 00 15 30Coffee BreakFlex Lab A B15 30 18 304 practicals in parallelPractical 1 Isothermal Titration Calorimetry ITC and Dynamic Light Scattering DLS Agatha Rosenthal Malvern Panalytical GermanyBernd Tartsch Malvern Panalytical GermanyPractical 2 Nano Differential Scanning Fluorimetry nano DSF and MicroScale Thermophoresis MST Arpita Kundu NanoTemper Germany Jan Schnatwinkel NanoTemper Germany Practical 3 Size Exclusion Chromatography coupled to Multi Angle Light Scattering and Dynamic Light Scattering SEC MALS DLS and Mass PhotometryMelisse Erasmus Refeyn UKSebastian Joecks Refeyn UKChristian Sieg Wyatt GermanyPractical 4 Cryo Electron Microscopy cryo EM Simon Fromm EMBL Heidelberg Germany Training Lab BIC building room 12518 30 20 00DinnerRoof top lounge 20 00Departure to HotelATC Entrance Day 2 Wednesday 30 November 2022 Time Europe Berlin SessionLocation09 00 09 10Overview of the dayFlex Lab A B 09 10 12 104 practicals in parallelPractical 1 Isothermal Titration Calorimetry ITC and Dynamic Light Scattering DLS Agatha Rosenthal Malvern Panalytical GermanyBernd Tartsch Malvern Panalytical GermanyPractical 2 Nano Differential Scanning Fluorimetry nano DSF and MicroScale Thermophoresis MST Arpita Kundu NanoTemper GermanyJan Schnatwinkel NanoTemper Germany Practical 3 Size Exclusion Chromatography coupled to Multi Angle Light Scattering and Dynamic Light Scattering SEC MALS DLS and Mass PhotometryMelisse Erasmus Refeyn UKSebastian Joecks Refeyn UKChristian Sieg Wyatt GermanyPractical 4 Cryo Electron Microscopy cryo EM Simon Fromm EMBL Heidelberg Germany Training Lab BIC building room 12512 10 13 15LunchCanteen13 15 14 00Lecture Quality control of protein RNA complexes for structural studiesPravin Kumar Ankush Jagtap EMBL Heidelberg GermanyFlex Lab A B14 00 14 45Lecture Quality control for membrane proteinsMelanie McDowell Max Planck Institute of Biophysics GermanyFlex Lab A B14 45 15 15Coffee breakFlex Lab A B15 15 18 154 practicals in parallelPractical 1 Isothermal Titration Calorimetry ITC and Dynamic Light Scattering DLS Agatha Rosenthal Malvern Panalytical GermanyBernd Tartsch Malvern Panalytical GermanyPractical 2 Nano Differential Scanning Fluorimetry nano DSF and MicroScale Thermophoresis MST Arpita Kundu NanoTemper GermanyJan Schnatwinkel NanoTemper Germany Practical 3 Size Exclusion Chromatography coupled to Multi Angle Light Scattering and Dynamic Light Scattering SEC MALS DLS and Mass PhotometryMelisse Erasmus Refeyn UKSebastian Joecks Refeyn UKChristian Sieg Wyatt GermanyPractical 4 Cryo Electron Microscopy cryo EM Simon Fromm EMBL Heidelberg Germany Training Lab B18 15Dinner downtown Day 3 Thursday 1 December 2022 Time Europe Berlin SessionLocation09 00 09 10Overview of the dayFlex Lab A B09 10 10 40Lecture CD and Optical Spectroscopy for Protein Quality ControlAndr Matagne Universit de Li ge BelgiumFlex Lab A B10 40 11 00Coffee breakFlex Lab A B11 00 11 45Lecture Protein production characterisation and quality control processes in industryInessa De BASF GermanyFlex Lab A B11 45 12 30Lecture Why should we use Proteomics for protein quality controlling Mandy Rettel EMBL Heidelberg GermanyFlex Lab A B12 30 13 30LunchCanteen13 30 14 15Lecture Production of protein complexes for cryo EMSebastian Eustermann EMBL Heidelberg GermanyFlex Lab A B14 15 14 45Lecture Advanced characterisation of membrane proteinBertrand Raynal Institut Pasteur FranceFlex Lab A B14 45 15 15optional Core Facility TourCore Facility15 00 15 30Coffee breakFlex Lab A B15 30 18 304 practicals in parallelPractical 1 Isothermal Titration Calorimetry ITC and Dynamic Light Scattering DLS Agatha Rosenthal Malvern Panalytical GermanyBernd Tartsch Malvern Panalytical GermanyPractical 2 Nano Differential Scanning Fluorimetry nano DSF and MicroScale Thermophoresis MST Arpita Kundu NanoTemper GermanyJan Schnatwinkel NanoTemper Germany Practical 3 Size Exclusion Chromatography coupled to Multi Angle Light Scattering and Dynamic Light Scattering SEC MALS DLS and Mass PhotometryMelisse Erasmus Refeyn UKSebastian Joecks Refeyn UKChristian Sieg Wyatt GermanyPractical 4 Cryo Electron Microscopy cryo EM Simon Fromm EMBL Heidelberg GermanyTraining Lab BIC building room 11418 30 20 00DinnerEMBL Canteen20 00Departure to Hotel Day 4 Friday 2 December 2022 Time Europe Berlin SessionLocation09 30 11 00Round table with speakers instructors and all participantsRooftop lounge11 00 11 30Coffee breakFlex Lab A B 11 30 12 00Feedback and closing remarksFlex Lab A B 12 00 12 15Departure and packed lunch Practical information Registration fees and motivation letter The course is limited to 16 participants For selection purposes please note that your application will not be considered without a letter of motivation Registration Registration fees include admission course materials COVID 19 safety measures meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Academia 600PhD Student 600Industry 1100 Confirmation and payment The registration fee should be paid only after acceptance to the course The results will be announced approximately 2 3 weeks after the application deadline Motivation letter submission After you have logged in and successfully registered you will receive an email asking you to submit your motivation letter Click on the link provided and enter your motivation letter in the text box provided Alternatively you can submit your motivation letter by clicking on the link on the confirmation page directly after registering Instructions Include your relevant skills experience and qualifications showing why you would be suitable for the course Explain why you would like to attend including what you can contribute and how you think you will benefit from the course Please note The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised For more detailed information follow the instructions provided in our video on how to submit a course motivation letter Further details For further information about registration and motivation letter submission please refer to the FAQ page Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of both registration fee waivers and travel grants Availability is limited to participants attending on site events in Heidelberg and will be indicated during the abstract or motivation letter submission process Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course or conference Travel grant The travel grant will cover the cost of travel airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Course EMBL Conference or EMBO EMBL Symposium from within Europe up to 1000 for participants travelling to an EMBL Course EMBL Conference or EMBO EMBL Symposium from outside Europe up to 500 for any participant travelling to an EMBO Practical Course or EMBO Workshop up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Practical Course or EMBO Workshop Registration fees are only covered for EMBO Practical Courses or EMBO WorkshopsThe organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Boehringer Ingelheim Fonds travel grant Applies to selected courses only Availability will be indicated during the abstract or motivation letter submission process This grant covers costs related to your attendance at the course registration travel and accommodation costs The grant is restricted to PhD students and postdocs who conduct basic biomedical research Whether you are eligible to apply for a travel grant depends on when you received your university entrance qualification e g Abitur A Levels High School Diploma Final State Examination for PhD and MD students as well as graduates the university entrance qualification must not have been obtained more than 11 years ago at the time of the envisaged course for postdocs the university entrance qualification must not have been obtained more than 13 years ago at the time of the envisaged course Application You may apply for financial assistance when submitting your motivation letter for courses and abstract for conferences In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application For the Boehringer Ingelheim Fonds Travel Grant there is a pre application question during the motivation letter submission process and if selected you will be requested to complete a standard form and documentation consisting of your travel expense estimation Selection The scientific organisers will select the recipients of all financial assistance during the motivation letter or abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection is based on your current work or study location the reasons for needing financial support and the impact this event will have on your career Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details See our list of external funding opportunities and information on attending a conference as an event reporter For further information about financial assistance please refer to the FAQ page Accommodation and shuttles Hotel Single rooms have been reserved for 4 nights 28 November 02 December 2022 at the ISG Hotel After the selection process selected participants should contact the hotel directly to make a booking booking code PQC22 01 We recommend that all course participants stay at the ISG Hotel which is the dedicated hotel for the course Local transport Shuttle buses will go from the ISG Hotel to EMBL and back mornings and evenings The bus schedule can be found here Further details Address EMBL Heidelberg Meyerhofstra e 1 69117 Heidelberg GermanyFor further information on getting to EMBL Heidelberg visit our Travel Information page For enquiries about accommodation and local transportation please refer to the FAQ page Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page COVID 19 related questions COVID 19 information for on site events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other events or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9...

Karine Lapouge, Kim Remans

EMBL Course

EMBL Heidelberg

23 November 2022

The environmental impact of computational biology

Edit

November 23, 2022 15:302022WebinarVirtual

Description The environmental impact of scientific computing computational biology in particular is a growing concern in light of the urgency of the climate crisis and there is widespread interest in the research community so what can we all do about it Tackling this issue and making it easier for scientists to engage with sustainable computing is what motivated the Green Algorithms project During this webinar we will discuss what we learned along the way how to estimate the impact of our work and dive into the carbon footprint of common bioinformatic analyses We will also highlight the levers scientists and institutions have to make their research more sustainable debate the ethical implications of these environmental costs and examine what is still needed moving forward About the speaker Dr Lo c Lannelongue is a Research Associate in Biomedical Data Science in the Cardiovascular Epidemiology Unit and the Inouye lab at the University of Cambridge He is also a College Post Doctoral Associate at Jesus College Cambridge and an Associate Fellow of Advance HE Lo c developed the Greener Algorithms project in collaboration with Jason Grealey and Michael Inouye to understand the carbon footprint of analyses and promote best practices in green computing...

Loïc Lannelongue

Virtual

23 November - 25 November 2022

Managing a bioinformatics core facility

Edit

November 23, 2022 00:002022CourseVirtual

Description This knowledge exchange workshop is an opportunity for managers of bioinformatics core facilities to learn from EMBL EBI s service teams and from each other These facilities play an essential role in enabling research in the molecular life sciences The landscape is constantly evolving as new research tools emerge as experiments become increasingly data intensive and as their clients experimental researchers become more exposed to the power of data driven biology This course will allow participants to share experiences discuss challenges and solutions that they face and plan ways to cope with the ever changing demands raised by the molecular life science field It will include sessions to learn from data providers at EMBL EBI hear how others have tackled common problems and work together to design core services...

Sophie Spencer

Virtual

22 November - 24 November 2022

Open Virtual Ensembl API Workshop

Edit

November 22, 2022 00:002022CourseVirtual

Description Work with Ensembl to master the Ensembl REST API and flexibly access genome wide data such as genes variants regulatory features homologues and alignments...

Aleena Mushtaq

Virtual

17 November 2022

Uncovering protein function with UniProt

Edit

November 17, 2022 15:002022WebinarVirtual

Description The webinar will cover what functional information is available in UniProt and where that information comes from It will also describe how the information is added to the resource and how to find it on the UniProt website...

Michele Magrane

Virtual

15 November 2022

Edit

November 15, 2022 00:002022ConferenceEMBL Heidelberg, Virtual

Description OverviewSpeakersProgrammePractical informationSponsorsMedia kit Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Please see EMBL s COVID 19 safety policy for testing and other requirements if attending the on site event Conference overview Genomics proteomics and quantitative imaging are rapidly moving fields with technological innovations and new biological insights occurring on an almost monthly basis For example mass spectrometry based proteomics is now able to quantitatively assess close to 80 of the proteome which can nowadays be obtained from very low cell numbers An even greater jump in sensitivity has recently revolutionized genomics with the rapid spread of measurements at the resolution of single molecule and single cells Development of new methods and instruments has led to the emergence of high content quantitative microscopy that enables quantification of dozens of phenotypic readouts in single cells A common feature of all these techniques is their ability to generate large amounts of high resolution quantitative data characterizing biological systems at scales ranging from molecular to organismal level A topical challenge is to convert this data into predictive quantitative models of biological systems From functional genomics to systems biology is a venue for scientific leaders to discuss their data beyond their field and promote the emergence of ideas and concepts to bridge the gap between technologies and scales to model complex biological systems Session topics From molecules to cells From cells to organsFrom biological systems to disease What past participants say about the conference Attending this conference revealed ideas of methods and tools that can be applied by my team in some aspects of our planned future research The conference organization and execution skills surpassed the expectation I had of an EMBL event Thank you for this great experience Joy Ehiwuogu Onyibe Federal Institute of Industrial Research Oshodi FIIRO Nigeria A very beautifully organized virtual conference with excellent presentations in a professional environment that encourages young researchers Muhammad Nisar Ali Nigde Omer Halisdemir University Turkey Speakers Speakers Stein Aerts KU Leuven Belgium Pedro Beltrao EMBL EBI Hinxton UK and ETH Zurich Switzerland Lacra Bintu Stanford University USA Bernd Bodenmiller University of Zurich ETH Zurich Switzerland Giovanni D Angelo Swiss Federal Institute of Technology Lausanne Switzerland Carl de Boer University of British Columbia Canada Leeat Keren Weizmann Institute of Science Israel Arnaud Krebs EMBL Heidelberg Germany Anna Kreshuk EMBL Heidelberg Germany Mounia Lagha The Institute of Molecular Genetics of Montpellier France Prisca Liberali Friedrich Miescher Institute for Biomedical Research Switzerland Julia Mahamid EMBL Heidelberg Germany Christine Mayr Memorial Sloan Kettering Cancer Center USA Marcelo Nollmann CNRS INSERM France Athma Pai University of Massachusetts Chan Medical School USA Lucas Pelkmans University of Zurich Switzerland Alexandros Pertsinidis The Sloan Kettering Institute USA Markus Ralser Charit Universit tsmedizin Berlin Germany Juri Rappsilber Technische Universit t Berlin Germany Mikhail Savitski EMBL Heidelberg Germany Georg Seelig University of Washington USA Virtual speaker Hugo Snippert University Medical Center Utrecht The Netherlands Winston Timp John Hopkins University USA Judit Villen University of Washington USA Virtual speaker Scientific organisers Arnaud Krebs EMBL Heidelberg Germany Prisca Liberali Friedrich Miescher Institute for Biomedical Research Switzerland Mikhail Savitski EMBL Heidelberg Germany Georg Seelig University of Washington USA Conference organiser Raili Pall EMBL Heidelberg Germany Programme Got something to say Tweet it EMBOOmics For registered participants recorded talks will be accessible on demand for 2 weeks after the end of the event unless indicated otherwise Please find the poster listing here Day 1 Tuesday 15 November 2022 Time Europe Berlin Speaker12 15 13 30Registration and light refreshments13 30 13 45Opening remarks by Prisca Liberali and Arnaud Krebs13 45 18 00Session 1 From molecules to cellsChairs Mounia Lagha The Institute of Molecular Genetics of Montpellier France and Dan Lu Harvard Medical School USA13 45 14 10High throughput discovery and systematic sequence characterization of human transcriptional regulatorsLacra Bintu Stanford University USA14 10 14 30Deep mutational scanning of entire human protein interaction domain families Guillaume Diss Friedrich Miescher Institute for Biomedical Research Switzerland14 30 14 55Self organization in intestinal organoidsPrisca Liberali Friedrich Miescher Institute for Biomedical Research Switzerland14 55 15 15SPIDR a novel and highly multiplexed method for mapping RNA protein interactions to comprehensively study post transcriptional gene expression regulation Marko Jovanovic Columbia University USA15 15 15 40In cell interaction networks to understand integrated processesJuri Rappsilber Technische Universit t Berlin Germany 15 40 16 10Coffee break16 10 16 35Inspecting roles of 3D chromatin organization in transcription by multiplexed chromatin imagingMarcelo Nollmann CNRS INSERM France16 35 16 55Uncovering the molecular rules of chromatin module formationJudith Kribelbauer Swiss Federal Institute of Technology Lausanne Switzerland16 55 17 15Genomic context and histone marks define pioneer binding to nucleosomes Luca Mariani Brigham and Women s Hospital Harvard Medical School USA17 15 17 35Single molecule live cell imaging shows that DNA supercoiling restricts the transcriptional bursting of neighboring eukaryotic genesTineke Lenstra Netherlands Cancer Institute Oncode Institute The Netherlands17 35 18 00Analysis of tumor ecosystems by spatial proteomics for precision medicineBernd Bodenmiller University of Zurich ETH Zurich SwitzerlandRecording not available 18 00 18 30Available for onsite participants onlyPanel discussion 1 Understanding genomes current breakthrough in the field with pre dinner drinks at ATC Foyer Panellists Lacra Bintu Stanford University USAJustin Crocker EMBL Heidelberg GermanyMounia Lagha The Institute of Molecular Genetics of Montpellier FranceZohar Shipony Ultima Genomics IsraelModerated by Arnaud Krebs EMBL Heidelberg Germany18 30 20 00Dinner EMBL canteen 20 00 21 30Social event pub quiz EMBL canteen 21 30 22 30Social event networking drinks ATC Rooftop Lounge Day 2 Wednesday 16 November 2022 Time Europe Berlin Speaker09 00 12 10Session 2 From molecules to cells continued Chairs Judith Kribelbauer Swiss Federal Institute of Technology Lausanne Switzerland and Guillaume Diss Friedrich Miescher Institute for Biomedical Research Switzerland09 00 09 25Biochemical activity is the default DNA state in eukaryotesCarl de Boer University of British Columbia Canada09 25 09 45Dynamic p53 post translational modifications regulate cellular fatesDan Lu Harvard Medical School USA09 45 10 05Chromatin accessibility is a two tier process regulated by transcription factor pioneering and enhancer activation Kaelan Brennan Stowers Institute for Medical Research USA10 05 10 30Elucidating mechanisms underlying coupled transcription initiation and 3 end cleavagAthma Pai University of Massachusetts Chan Medical School USA10 30 11 00Coffee break 11 00 11 25Understanding gene regulation using single molecule genomicsArnaud Krebs EMBL Heidelberg Germany11 25 11 45A race to identify the genes that support neutrophil cell migrationNathan Belliveau University of Washington HHMI USA11 45 12 10Revealing promoter enhancer communication mechanisms by high resolution single gene imagingAlexandros Pertsinidis The Sloan Kettering Institute USARecording not available12 10 13 45Lunch13 45 15 45Poster session 1 odd numbers ATC Helix APoster listing15 45 18 55Session 3 From cells to organsChairs Nathan Belliveau University of Washington HHMI USA and Lacra Bintu Stanford University USA15 45 16 10Multimodal perception links cellular state to decision making in single cellsLucas Pelkmans University of Zurich Switzerland16 10 16 30Clonally resolved single cell multi omics identifies routes of cellular differentiation in acute myeloid leukemiaLars Velten Center for Genomic Regulation CRG Spain16 30 16 50CRISPRi screen of schizophrenia risk genes elucidates the role of epigenetic regulators in neurons and progenitorsAnnique Claringbould EMBL Heidelberg Germany16 50 17 15Gene expression dynamics during the awakening of the zygotic genomeMounia Lagha The Institute of Molecular Genetics of Montpellier FranceRecording not available17 15 17 45Coffee break 17 45 18 10Finding biology in microscopy images with machine learningAnna Kreshuk EMBL Heidelberg Germany18 10 18 30Barcode free predictions of cell lineages from single cell transcriptome dataAlmut Eisele EPFL SwitzerlandRecording not available18 30 18 55Learning the rules of mRNA processing from massivelyparallel experiments and machine learningGeorg Seelig University of Washington USA Virtual speaker 18 55 20 30Dinner EMBL canteen Day 3 Thursday 17 November 2022 Time Europe Berlin Speaker09 00 12 05Session 4 From cells to organs continued Chairs Lars Velten Center for Genomic Regulation CRG Spain and Christine Mayr Memorial Sloan Kettering Cancer Center USA09 00 09 25Sphingolipids control dermal fibroblast heterogeneityGiovanni D Angelo Swiss Federal Institute of Technology Lausanne Switzerland09 25 09 45Applications of optimal transport theory to single cell analysesAngela Goncalves German Cancer Research Center DKFZ Germany09 45 10 05Can we accurately estimate gene regulatory networks from single cell data Julio Saez Rodriguez University of Heidelberg Germany10 05 10 35Coffee break 10 35 11 00Unraveling the tumor microenvironment using multiplexed imagingLeeat Keren Weizmann Institute of Science IsraelRecording not available11 00 11 20RANKL dependent ONECUT2 regulation of Enterocyte and Microfold cell differentiation in the small intestine a multi omics studyMaria Victoria Luna Velez Radboud University Nijmegen The Netherlands11 20 11 40Laboratory evolution of flies to morphogen dosage via rapid maternal changes reveals predictable outcomesJustin Crocker EMBL Heidelberg Germany11 40 12 05Heterogeneity in tumors evolving genomes at single cell resolutionHugo Snippert University Medical Center Utrecht The Netherlands12 05 13 30Lunch Optional walk run together registered participants only 13 30 15 30Poster session 2 even numbers ATC Helix APoster listing15 30 18 40Session 5 From biological systems to diseaseChairs Frank Albert University of Minnesota USA and Athma Pai University of Massachusetts Chan Medical School USA15 30 15 55A high dimensional atlas of phosphorylation dependent signalingJudit Villen University of Washington USA Virtual speaker 15 55 16 20Functional proteomics to assess the system scale nature of metabolismMarkus Ralser Charit Universit tsmedizin Berlin Germany16 20 16 40ProteasomeID quantitative mapping of proteasome interactomes and substrates for in vitro and in vivo studiesAlessandro Ori Leibniz Institute on Aging Fritz Lipmann Institute Germany16 40 17 05Towards a tissue specific and structurally resolved human interactomePedro Beltrao EMBL EBI Hinxton UK and ETH Zurich Switzerland17 05 17 35Coffee break 17 35 17 55Correlated light and electron microscopy volume imaging of organoid cell culturesEdoardo D Imprima EMBL Heidelberg GermanyRecording not available17 55 18 15From regulatory landscapes to complex intercellular dependencies using the gastruloid model systemLuca Braccioli The Netherlands Cancer Institute The Netherlands18 15 18 40Enabling discovery by in cell structural biologyJulia Mahamid EMBL Heidelberg Germany18 40 19 10Available for onsite participants onlyPanel discussion 2 From protein identification to function with pre dinner drinks at ATC Foyer Panellists Pedro Beltrao EMBL EBI Hinxton UK and ETH Zurich SwitzerlandGuillaume Diss Friedrich Miescher Institute for Biomedical Research SwitzerlandMarko Jovanovic Columbia University USARodrigo Villase or Biomedical Center Munich GermanyModerated by Mikhail Savitski EMBL Heidelberg Germany19 10 21 00Conference dinner EMBL canteen 21 00 23 00Social evening with live DJ ATC Rooftop Lounge Day 4 Friday 18 November 2022 Time Europe Berlin Speaker09 00 12 30Session 6 From biological systems to disease continued Chairs Pedro Beltrao EMBL EBI Hinxton UK and ETH Zurich Switzerland and Alessandro Ori Leibniz Institute on Aging Fritz Lipmann Institute Germany 09 00 09 25Deciphering gene regulatory networks and enhancer logic from single cell multi omics dataStein Aerts KU Leuven Belgium09 25 09 45Exon resolution functional genomics uncovers critical protein regions for cellular functionThomas Gonatopoulos Pournatzis National Cancer Institute National Institutes of Health USARecording not available09 45 10 05Targeted transcription factor degradation and nascent transcriptomics reveal a new model of core transcriptional regulatory circuitryMaxim Pimkin Dana Farber Cancer Institute and Boston Children s Hospital and Harvard Medical School10 05 10 30Biophysical proteomicsMikhail Savitski EMBL Heidelberg Germany10 30 11 00Coffee break 11 00 11 25Identification of global and gene specific regulators of alternative polyadenylation using Perturb seqChristine Mayr Memorial Sloan Kettering Cancer Center USA 11 25 11 45Exploring the vulnerabilities of EGFR dependent breast cancer cells with single cell lineage tracingMelania Franchini University of Naples Federico II Italy11 45 12 05Genetic variation in ubiquitin system genes creates complex pathway specific effects on proteasomal protein degradation Frank Albert University of Minnesota USA12 05 12 30Decoding the central dogma with single moleculesWinston Timp John Hopkins University USA12 30 12 45Closing remarks and poster prize announcement12 45Packed lunch and departure13 15Optional Shuttle bus to Frankfurt Airport Terminal 1 Tickets can be purchased on site during the conference for 25 EUR Practical information Registration fees and abstract submission On site registration fees include admission conference materials COVID 19 safety measures meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Virtual registration fees include access to all of the talks live streamed and on demand and facility to submit questions On site Academia 450On site PhD Student 350On site Industry 750Virtual Academia 175Virtual PhD Student 125Virtual Industry 225 NO visa support letters will be issued until payment of the registration fee is confirmed Accredited journalists may be eligible to register for complimentary press registration Registrants may be required to provide accreditation or equivalent proof of press membership after registration Please contact Raili Pall for more information Please note that we do not offer complimentary registrations for editors of scientific journals Confirmation and payment Registration will be on a first come first served basis Your place can only be confirmed after payment of the registration fee If you are added to our waiting list please consider taking advantage of our offerings to participate virtually On site participants Types of payments accepted are international bank transfers and credit card payments Virtual participants We are only able to accept card payments In exceptional cases we can accept bank transfers Please contact events embl de for details Abstract submission Only registered participants attending the on site event are eligible to submit an abstract Abstracts will not be accepted from virtual participants After you have logged in and successfully registered you will receive an email asking you to submit your abstract Click on the link provided and enter your abstract in the text box provided Alternatively you can submit your abstract by clicking on the link on the confirmation page directly after registering The same login credentials are used for both processes Please note Title The title should not exceed 20 words Only the first word of the title should start with a capital letter and the rest of the title should be in lowercase Authors and affiliations Please fill in the author s details as requested in the online form The compulsory details are First Name Last Name Organisation Name Affiliation or Company Country and Email Mark only one author as the role of First author and please don t forget to indicate who will be presenting The order of the authors will be listed as follows First Author Co First Author alphabetically if multiple co author s in the order added by the submitter Presentation types When submitting your abstract you can apply for an oral or poster presentation A selection process will take place with the results announced 2 3 weeks after the abstract submission deadline Please check our FAQs pages for further information on how to submit an abstract Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of both registration fee waivers and travel grants Availability is limited to participants attending on site events in Heidelberg and will be indicated during the abstract or motivation letter submission process Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course or conference Travel grant The travel grant will cover the cost of travel airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Course EMBL Conference or EMBO EMBL Symposium from within Europe up to 1000 for participants travelling to an EMBL Course EMBL Conference or EMBO EMBL Symposium from outside Europe up to 500 for any participant travelling to an EMBO Practical Course or EMBO Workshop up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Practical Course or EMBO Workshop Registration fees are only covered for EMBO Practical Courses or EMBO WorkshopsThe organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant EMBO practical courses and workshops only For EMBO Practical Course or EMBO Workshop participants with children there is the possibility to apply for a childcare grant to offset child care costs incurred by participants or speakers when participating at a course or conference Eligible costs include fees for a baby sitter or child care facility travel costs for a care giver or travel costs for taking the child to the meeting etc Please note that priority will be given to early stage researchers A maximum amount of 500 EUR can be awarded per participant applying for an EMBO Childcare Grant In order to apply for this grant for EMBO Workshops you must be registered by the abstract submission deadline Application You may apply for financial assistance when submitting your motivation letter for courses and abstract for conferences In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Selection The scientific organisers will select the recipients of all financial assistance during the motivation letter or abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection is based on your current work or study location the reasons for needing financial support and the impact this event will have on your career Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details View our list of external funding opportunities and information on attending a conference as an event reporter For further information about financial assistance please refer to the FAQ page Accommodation and shuttles Accommodation is not included in the conference registration fee As further changes in our events are possible due to COVID 19 you should book flights trains and hotels with flexible options and favourable cancellation conditions The hotels below have rooms on hold for participants until 14 October 2022 in some cases at special rates Please quote the booking code OMX22 01 and confirm the exact price of the room with the hotel directly Hotel AnlageHotel ibis HeidelbergPremier Inn Heidelberg CityHotel Bayrischer Hof ISG Hotel Staycity Aparthotel HeidelbergB B HotelLeonardo Hotel Heidelberg City CentreHotel Vier Jahreszeiten HeidelbergExzellenz Hotel Meininger HeidelbergHotel Holl nder Hof Hotel Monpti Conference shuttle buses Conference shuttle buses are free of charge for participants and depart from designated bus stops near the hotels to EMBL and back mornings and evenings Download the conference bus schedule here The bus stops for this conference are Staycity Aparthotel Speyerer Str 7 Kurf rsten Anlage opposite Main Train Station Premier Inn Hotel Kurf rsten Anlage 23 Leonardo Hotel City Centre Bergheimer Str 63 Neckarm nzplatz Heidelberg Tourist Information Peterskirche Bus stop ISG Hotel View Conference shuttle bus stops and hotels in a larger map Please note that not every bus stop will be used for every event Further details Address EMBL Meyerhofstra e 1 69117 Heidelberg Germany For further information on getting to EMBL Heidelberg visit Public Transportation to the Venue For information about accommodation and local transportation please refer to the FAQ page On site information Catering All meals and coffee breaks are included in the registration fee Our catering staff will prepare a wide variety of vegetarian meals meat and fish dishes soups pasta fresh fruit and vegetables as well as a variety of desserts Please wear your badge at all times when serving yourself No food or drinks are allowed in the auditorium Charging lockers There are lockers available next to the stairs leading down into the Auditorium You will find some of those equipped with sockets to charge your smartphone tablet etc Electricity and charging station In most places the electricity is 220 volts AC 50 cycles An adaptor and a plug that fits the German socket may be needed for your appliances laptop i e American Japanese etc A USB charging station for electronic devices is available at the registration desk EMBL merchandise EMBL Merchandise is available on Mon Thu 9 am 12 pm If you are interested in purchasing an EMBL souvenir products presented in the glass display in the registration area please ask at the registration desk for more information Health and safety notes Please read EMBL s COVID 19 safety policy for on site events Do not smoke in any EMBL building Eating and drinking is prohibited in the Auditorium and all laboratories Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required The first aid room is located next to the ATC Registration Desk room 10 205 Dial the Emergency number 222 from any EMBL internal phone only Where is the accident What happened How many injured Emergency number 06221 387 7821 from mobile phones Please report all accidents to the conference officer at the registration desk In case of fire Press the nearest fire alarm button or the Emergency number 222 from any internal phone A loud fire alarm will go off if an evacuation is required On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting pointsDo not use the lifts Beyond first aid Please remember to bring your own medication if needed to the conference Note that the next pharmacy is a 4 minute drive from the EMBL but for many medications you will be required to see a doctor to get a prescription Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg In any case the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary Internet Wi Fi is available everywhere on the premises no password required just log on to ATC Guest The eduroam network secure world wide roaming access service developed for the international research and education community is also available Lost and found Lost and Found are kept at the registration desk until the end of the conference Luggage There are lockers available on site to store your luggage which require a 2 EURO coin to operate There is another luggage room on level E0 which is free to use but remains unlocked during the conference Nursing room There is a nursing room available in the ATC Rooftop Lounge on level A29 Photography During the conference an EMBL Photographer may be taking photographs If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Printing We can help printing your boarding passes train ticket Please send it to events embl de and collect your print outs at the registration desk Room for prayer yoga and meditation There is a room for prayer mediation and yoga located on level E0 behind the Auditorium Please be respectful of other participants using the room Sightseeing A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing Travel to and from the venue During the event we provide conference shuttle buses to and from EMBL In addition there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time Information on the conference shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page Useful German expressions EnglishGermanHelloHalloGoodbyeAuf WiedersehenGood morningGuten MorgenGood afternoonGuten TagGood eveningGuten AbendGood nightGute NachtI m sorryTut mir leidExcuse me Entschuldigen SieHow are you Wie geht s I m fine thanks And you Mir geht es gut danke und dir Ihnen What is your nameWie heisst du Wie heissen Sie My name isIch heisseDo you speak EnglishSprechen Sie Englisch I don t understandIch verstehe nichtPlease speak more slowlyK nnen Sie bitte langsamer sprechenThank youDanke sch nWhere is the toilet Wo ist die Toilette Please call me a taxiBitte rufen Sie mir ein TaxiHow do I get to Wie komme ich zum zur A beer two beers pleaseEin Bier zwei Bier bitteA glass of red white wine pleaseEin Glas Rot Weisswein bitteThe menu pleaseDie Speisekarte bitteIs there a local speciality Gibt es eine Spezialit t aus dieser Gegend I m VegetarianIch bin VegetarierIt was deliciousEs war hervorragendThe bill pleaseDie Rechnung bitteI have a headacheIch habe KopfschmerzenI have a sore throatIch habe HalsschmerzenMy stomach hurtsIch habe MagenschmerzenI m allergic toIch bin allergisch gegenI need a doctor who speaks EnglishGibt es einen Arzt der Englisch spricht Virtual participation What s included Access to all the livestreamed talksVideo library of the recorded talks during and after the eventFacility to submit questions Please note that only on site participants are able to submit abstracts and participate in the poster sessions Event platform We are using an event platform for this conference More information about the platform will be shared ahead of the conference Guidelines Do not broadcast the conference to unregistered participants You are encouraged to tweet and post about the event Tweet unless the speaker specifically says otherwise but be mindful of unpublished data Please do not capture transmit or redistribute data presented at the meeting Additional information can be found in our Code of Conduct Health and well being It is important to stay healthy and move around especially when you are attending an event virtually We have put together a few coffee break stretches and yoga videos in the conference platform for you to enjoy during the event How to ask questions Please use the Q A function in the event platform If you have any other questions you can go to the Help Desk in the event platform Click on more on the top menu and click Help Desk Time zone The programme is planned based on the Europe Berlin time zone unless otherwise stated Please take your time zone into consideration when planning your attendance Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page COVID 19 related questions COVID 19 information for on site events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Bronze sponsor Media partner International Union of Biochemistry and Molecular Biology Molecular Systems Biology an EMBO Press journal Open Biology a Royal Society journal Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information on sponsoring possibilities If you are interested in becoming a media partner of this event please visit our media partnerships webpage Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9...

Arnaud Krebs, Prisca Liberali, Mikhail Savitski, Georg Seelig

EMBO Workshop

EMBL Heidelberg, Virtual

14 November - 18 November 2022

Genome bioinformatics: resequencing and variant calling

Edit

November 14, 2022 00:002022CourseVirtual

Description A guide to the technology analysis workflows tools and resources for next generation sequencing data analysis This virtual course will provide insights and training into how biological knowledge can be derived from genomics experiments and explain different approaches in analysing such data The main focus will be on introducing sequence informatics re sequencing and variant calling during the analysis of higher eukaryotes with an emphasis on human genetic research Throughout the week more advanced topics will introduce the creation of pipelines automation and the scaling up of analysis experiments Practical sessions will enable participants to process training datasets and apply appropriate statistical methods in their analyses There will be no opportunity to work with personal research data during the course Virtual course Participants will learn via a mix of pre recorded lectures live presentations and trainer Q A sessions Practical experience will be developed through group activities and trainer led computational exercises Live sessions will be delivered using Zoom with additional support and communication via Slack Pre recorded material will be made available to registered participants prior to the start of the course and in the week before the course there will be a brief induction session Computational practicals will run on EMBL EBI s virtual training infrastructure meaning participants will not require access to a powerful computer or install complex software on their own machines Participants will need to be available between the hours of 09 30 18 00 GMT each day of the course Trainers will be available to assist answer questions and further explain the analysis during these times...

Juanita Riveros

Virtual

13 November - 18 November 2022

Single-cell omics: deeper to genomics

Edit

November 13, 2022 00:002022CourseEMBL Heidelberg

Description OverviewSpeakersProgrammePractical informationSponsors Overview Please see EMBL s COVID 19 safety policy for testing and other requirements to attend this on site course Course overview Single cell sequencing is a rapidly evolving technique and is increasingly implemented in various research fields The whole workflow contains several critical and challenging steps from cell sampling over working with minute amounts of sample to data analysis and integration This hands on course will cover latest cutting edge techniques in single cell genomics Strand Seq single cell multiomics single cell DNTR sequencing during the wet lab practical sessions The computational part will address the basics of data analysing of the above mentioned techniques and also illustrate their integration In addition lectures and discussion rounds with key experts and technology developers in the field will provide the participants with a general background on single cell sequencing technologies and its applications Audience This course targets young scientists entering the field of single cell analysis and wanting to learn about the benefits and limitations of the approach by performing a complete single cell analysis workflow Modules resources Single cell isolation with FACS Single cell genomics using Strand Seq Single cell DNTR sequencing Single cell NGS data analysis Learning outcomes After finishing the course attendees will have an overview of available methods in single cell omics and a basic overview of data analysis of single cell NGS data sets genomics epigenetic and transcriptomics Attendees will also be able to set up some methods in their lab with the knowledge of the detailed protocol and troubleshooting What past participants say about the course This course provided clear guidelines and the latest approaches from researchers who have contributed throughout last years to the single cell field A truly enriching experience for single cell users to get knowledgeable about current methods and their capabilities Melissa Leija Salazar University College London Speakers Speakers trainers and staff Marco Beccuti University of Torino Italy Vladimir Benes EMBL Heidelberg Germany Eva Benito Garagorri EMBL Heidelberg Germany Raffaele Calogero University of Turin Italy Huaitao Cheng Karolinska Institutet Sweden Stephen Clark Altos Labs UK Francesca Cordero University of Torino Italy Qiaolin Deng Karolinska Institute Sweden Martin Enge Karolinska Institute Sweden Eileen Furlong EMBL Heidelberg Germany Karen Grimes Novartis Institute for Biomedical Research NIBR Switzerland Nina Habermann EMBL Heidelberg Germany Patrick Hasenfeld EMBL Heidelberg Germany Wolfram Hoeps EMBL Heidelberg Germany Ashok Kumar Jayavelu KiTZ Hopp Children s Cancer Center Heidelberg Germany Hyobin Jeong Hanyang University Republic of Korea Solrun Kolbeinsdottir Karolinska Institute Sweden Jan Korbel EMBL Heidelberg Germany Diana Ordonez EMBL Heidelberg Germany Mireia Osuna Lopez EMBL Heidelberg Germany David Porubsky University of Washington USA Johan Reimeg rd Uppsala University Sweden Kristina Roucova Charles University Czech Republic Sinem Saka EMBL Heidelberg Germany Ashley Sanders MDC Berlin Germany Anders St hlberg University of Gothenburg Sweden Oliver Stegle German Cancer Research Center Germany Catherine Stober Brasseur EMBL Heidelberg Germany C line Vallot Curie Institute France Laura Villacorta EMBL Heidelberg Germany Thomas Weber EMBL Heidelberg Germany Allan Zhao Karolinska Institute Sweden Scientific organisers Qiaolin Deng Karolinska Institute Sweden Jan Korbel EMBL Heidelberg Germany Anders St hlberg University of Gothenburg Sweden Elisabeth Zielonka EMBL Heidelberg Germany Course organisers Maryann Heck Deputy Head of Course and Conference Office EMBL Heidelberg Germany Irena Provaznikova Training Lab Technician EMBL Heidelberg Germany Aline Schnieder Course Conference Officer EMBL Heidelberg Germany Programme Got something to say Tweet it with EMBOSCOmics Some pre course work such as watching pre recordings protocol reading and computational exercises with estimated time 0 10 hours will be required and will be shared in advance of the course Some speakers may need to join virtually to give their lecture or Q A and the programme is subject to change Day 0 Onboarding session Monday 7 November 2022 Time Europe Berlin SessionLocation10 00 10 15On Boarding Day Welcome and short introductionVirtual10 15 10 45Course overview on eCampus introduction to pre course workVirtual10 45 11 00Questions and TroubleshootingVirtual Day 1 Sunday 13 November 2022 Time Europe Berlin SessionLocation08 40 09 00Bus to EMBLISG Hotel09 00 09 30Registration09 30 10 00Welcome and course overviewSession Chair Anders St hlbergFlex Lab A B10 00 11 00Networking activity Flash talksFlex Lab A B11 00 11 30Coffee Break 11 30 12 15Live Q A to pre recorded lecture Introduction to single cell analysis and applications opportunities limitations and standards in the fieldAnders St hlberg University of Gothenburg SwedenFlex Lab A B12 15 13 15LunchEMBL Canteen13 15 14 00Lecture Flow Cytometry and single cell samplingDiana Ordo ez EMBL Heidelberg GermanyFlex Lab A B14 00 15 30Practical work in groups and discussion Group a b Single Cell sampling by FACS Practical session 1 Group c d Interactive session SC genomics and transcriptomics Experimental design discussion round Training Lab B Flex Lab A B FACS15 30 17 00Practical work in groups Group a b DNTR Seq nuclear cytosolic fractionation Practical session 2 Interactive session SC genomics and transcriptomics Experimental design discussion round Group c d Single Cell sampling by FACS Practical session 1 Concurrent coffee breakTraining Lab B Flex Lab A B FACS 17 00 17 30Practical work in groups Group a b Interactive session SC genomics and transcriptomics Experimental design discussion roundGroup c d DNTR Seq nuclear cytosolic fractionation Practical session 2 Concurrent coffee breakTraining Lab B Flex Lab A B FACS 17 30 18 00Coffee break 18 00 18 45Lecture Single cell multi omics simultaneous whole genome and transcriptome analysis by DNTR Seq remote lecture Martin Enge Karolinska Institute SwedenFlex Lab A B18 45 19 30Lecture Single cell analysis in tracking embryo developmentQiaolin Deng Karolinska Institute SwedenFlex Lab A B19 30 21 30Poster session 1 1 8 with pizza and drinksATC Helix B Rooftop Lounge21 30Departure to HotelATC Entrance Day 2 Monday 14 November 2022 Time Europe Berlin SessionLocation08 40 09 00Bus to EMBLISG Hotel09 00 09 15Overview of the daySession Chair Anders St hlbergFlex Lab A B09 15 11 55Practical session 3 DNTR Seq Transcriptomics with flexible coffee break Introduction and Reverse transcription set upHuaitao Cheng Karolinska Institutet Sweden Solrun Kolbeinsdottir Karolinska Institutet Sweden Mireia Osuna Lopez EMBL Heidelberg Germany Laura Villacorta EMBL Heidelberg GermanyAllan Zhao Karolinska Institutet SwedenTraining Lab B Flex Lab A B FACS 11 55 12 55LunchEMBL Canteen12 55 13 25Live Q A to pre recorded lectures Single cell protein analysisSingle cell mass spectrometryAshok Kumar Jayavelu KiTZ Hopp Children s Cancer Center Heidelberg GermanyJohan Reimeg rd Uppsala University SwedenFlex Lab A B13 25 14 25Practical session 3 DNTR Seq TranscriptomicscDNA amplificationHuaitao Cheng Karolinska Institutet Sweden Solrun Kolbeinsdottir Karolinska Institutet Sweden Mireia Osuna Lopez EMBL Heidelberg Germany Laura Villacorta EMBL Heidelberg GermanyAllan Zhao Karolinska Institutet SwedenTraining Lab B14 25 15 10Lecture Innovations in single cell epigenomics remote lecture Stephen Clark Altos Labs UKFlex Lab A B15 10 15 55Lecture Single Cell ATAC Seq and its ApplicationsEileen Furlong EMBL Heidelberg GermanyFlex Lab A B15 55 17 55Practical session 3 DNTR Seq TranscriptomicscDNA cleanup quantification QCHuaitao Cheng Karolinska Institutet Sweden Solrun Kolbeinsdottir Karolinska Institutet Sweden Mireia Osuna Lopez EMBL Heidelberg Germany Laura Villacorta EMBL Heidelberg GermanyAllan Zhao Karolinska Institutet SwedenTraining Lab B17 55 19 25Practical session 3 DNTR Seq TranscriptomicscDNA dilution and fragmentation and library PCR set upHuaitao Cheng Karolinska Institutet Sweden Solrun Kolbeinsdottir Karolinska Institutet Sweden Mireia Osuna Lopez EMBL Heidelberg Germany Laura Villacorta EMBL Heidelberg GermanyAllan Zhao Karolinska Institutet SwedenTraining Lab B19 25 19 35Practical session 3 DNTR Seq TranscriptomicsFollow up QC resultsHuaitao Cheng Karolinska Institutet Sweden Solrun Kolbeinsdottir Karolinska Institutet Sweden Mireia Osuna Lopez EMBL Heidelberg Germany Laura Villacorta EMBL Heidelberg GermanyAllan Zhao Karolinska Institutet SwedenTraining Lab B19 35 21 00Career networking dinnerEMBL Canteen21 00Departure to HotelATC Entrance Day 3 Tuesday 15 November 2022 Time Europe Berlin SessionLocation08 40 09 00Bus to EMBLISG Hotel09 00 09 15Overview of the daySession Chair Qiaolin DengFlex Lab A B09 15 10 15Data Integration on Spatial LevelsOliver Stegle German Cancer Research Centre DKFZ EMBL Heidelberg GermanyFlex Lab A B10 15 10 30Live Q A to pre recorded lecture Imaging based spatial analysis in single cellsSinem Saka EMBL HeidelbergFlex Lab A B10 30 12 30Practical session 4 DNTR Seq GenomicsTn5 digestion and PCR amplification set up barcoding Huaitao Cheng Karolinska Institutet SwedenSolrun Kolbeinsdottir Karolinska Institutet SwedenMireia Osuna Lopez EMBL Heidelberg GermanyLaura Villacorta EMBL Heidelberg GermanyAllan Zhao Karolinska Institutet SwedenTraining Lab B12 30 13 30LunchEMBL Canteen13 30 15 00Practical session 4 DNTR SeqPooling and library clean upHuaitao Cheng Karolinska Institutet SwedenSolrun Kolbeinsdottir Karolinska Institutet SwedenMireia Osuna Lopez EMBL Heidelberg GermanyLaura Villacorta EMBL Heidelberg GermanyAllan Zhao Karolinska Institutet SwedenTraining Lab B15 00 15 30Practical session 4 DNTR SeqLibrary QCHuaitao Cheng Karolinska Institutet SwedenSolrun Kolbeinsdottir Karolinska Institutet SwedenMireia Osuna Lopez EMBL Heidelberg GermanyLaura Villacorta EMBL Heidelberg GermanyAllan Zhao Karolinska Institutet SwedenTraining Lab B15 30 16 00Coffee break 16 00 17 30Future in sequencing technologies and Genomics Core Facility TourVladimir Benes EMBL Heidelberg GermanyFlex Lab A B17 30 18 30Live Q A to pre recorded lecture Cancer Omics and Data ScienceJan Korbel EMBL Heidelberg GermanyFlex Lab A B18 30 20 00Poster session 2 9 16 with German Zwiebelkuchen and drinksATC Helix B Rooftop Lounge20 00Departure to HotelATC Entrance Day 4 Wednesday 16 November 2022 Time Europe Berlin SessionLocation08 40 09 00Bus to EMBLISG Hotel09 00 09 05Overview of the daySession Chair Eva BenitoFlex Lab A B 09 05 09 50Lecture Single cell genomics using Strand Seq and its applicationsAshley Sanders MDC Berlin GermanyFlex Lab A B09 50 10 50Practical session 5 Strand seq genomicsIntroduction and sample prep nuclei isolation and FACS analysis Eva Benito Garagorri EMBL Heidelberg GermanyKaren Grimes Novartis Institute for Biomedical Research NIBR SwitzerlandPatrick Hasenfeld EMBL Heidelberg GermanyAshley Sanders MDC Berlin GermanyCatherine Stober Brasseur EMBL Heidelberg GermanyTraining Lab B10 50 11 05Coffee break 11 05 12 05Practical session 5 Strand seq genomicssample prep FACS analysis robotics part 1 at FACS machine robotics demoEva Benito Garagorri EMBL Heidelberg GermanyKaren Grimes Novartis Institute for Biomedical Research NIBR SwitzerlandPatrick Hasenfeld EMBL Heidelberg GermanyAshley Sanders MDC Berlin GermanyCatherine Stober Brasseur EMBL Heidelberg GermanyGenecore12 05 13 05Group photo and lunch breakEMBL Canteen 13 05 14 15Practical session 5 Strand seq genomicssample prep FACS analysis gating for StrandSeq Working with real data with FlowJoEva Benito Garagorri EMBL Heidelberg GermanyKaren Grimes Novartis Institute for Biomedical Research NIBR SwitzerlandPatrick Hasenfeld EMBL Heidelberg GermanyAshley Sanders MDC Berlin GermanyCatherine Stober Brasseur EMBL Heidelberg GermanyComputer Training Lab14 20 15 35Practical session 5 Strand seq genomicsMNase digestion with sample clean up with flexible coffee breakEva Benito Garagorri EMBL Heidelberg GermanyKaren Grimes Novartis Institute for Biomedical Research NIBR SwitzerlandPatrick Hasenfeld EMBL Heidelberg GermanyAshley Sanders MDC Berlin GermanyCatherine Stober Brasseur EMBL Heidelberg GermanyTraining Lab B15 35 16 50Practical session 5 Strand seq genomics Library cleanup Eva Benito Garagorri EMBL Heidelberg GermanyKaren Grimes Novartis Institute for Biomedical Research NIBR SwitzerlandPatrick Hasenfeld EMBL Heidelberg GermanyAshley Sanders MDC Berlin GermanyCatherine Stober Brasseur EMBL Heidelberg GermanyTraining Lab B16 50 17 20Coffee break 17 20 19 50Lecture and computational practical 1 Data preprocessing QC imputation normalizationRaffaele Calogero University of Turin ItalyComputer Training Lab19 50Departure to HotelATC Entrance20 00 21 30DinnerISG Hotel Day 5 Thursday 17 November 2022 Time Europe Berlin SessionLocation08 40 09 00Bus to EMBLISG Hotel09 00 09 05Overview of the daySession Chair Raffaele CalogeroComputer Training Lab09 05 10 30Computational practical 2 Dimensionality reduction Raffaele Calogero University of Turin Italy Francesca Cordero University of Turin Italy Marco Beccuti University of Turin Italy Kristina Roucova Charles University Czech RepublicComputer Training Lab10 30 10 45Coffee break 10 45 12 30Computational practical 3 Clustering and depicting cluster specific gene markersRaffaele Calogero University of Turin Italy Francesca Cordero University of Turin Italy Marco Beccuti University of Turin Italy Kristina Roucova Charles University Czech RepublicComputer Training Lab12 30 13 30Technology lunch with tapasATC Rooftop Lounge13 30 15 00Computational practical 3 Clustering and depicting cluster specific gene markersRaffaele Calogero University of Turin Italy Francesca Cordero University of Turin Italy Marco Beccuti University of Turin Italy Kristina Roucova Charles University Czech RepublicComputer Training Lab15 00 15 15Break 15 15 16 00Lecture and demo Multiomics single cell data analysis DNTR Seq analysisMartin Enge Karolinska Institute SwedenFlex Lab A B16 00 18 30Computational practical 2 DNTR Seq data analysisHuaitao Cheng Karolinska Institute SwedenMartin Enge Karolinska Institute SwedenSolrun Kolbeinsdottir Karolinska Institute SwedenComputer Training Lab18 30 19 30Bus downtown HD free time city centre 19 30 21 30Course dinner downtown Day 6 Friday 18 November 2022 Time Europe Berlin SessionLocation08 40 09 00Bus to EMBLISG Hotel09 00 09 05Overview of the daySession Chair Elisabeth ZielonkaComputer Training Lab09 05 10 35Computational practical 2 DNTR Seq data analysisHuaitao Cheng Karolinska Institute SwedenMartin Enge Karolinska Institute SwedenSolrun Kolbeinsdottir Karolinska Institute SwedenComputer Training Lab10 35 11 20Application Lecture Single cell high throughput Chip Seq analysis in breast cancer tumors remote lecture C line Vallot Curie Institute France FranceFlex Lab A B 11 20 11 50Coffee break 11 50 12 45Computational practicals 3 Single cell genomics data analysis Data visualisation library selection ASHLEYS Karen Grimes EMBL Heidelberg GermanyHyobin Jeong Hanyang Universtiy Republic of Korea Ashley Sanders MDC Berlin Germany Thomas Weber EMBL Heidelberg Germany Wolfram Hoeps EMBL Heidelberg Germany Computer Training Lab12 45 13 45Lunch breakEMBL Canteen13 45 15 50Computational practicals 3 Computational practical Single cell genomics data analysis Strand Seq downstream analysis scTRIP breakpointRKaren Grimes EMBL Heidelberg GermanyHyobin Jeong Hanyang Universtiy Republic of Korea Ashley Sanders MDC Berlin Germany Thomas Weber EMBL Heidelberg Germany Wolfram Hoeps EMBL Heidelberg Germany Computer Training Lab15 50 16 05Coffee break 16 05 17 35Computational practicals 3 continued Single cell genomics data analysis Strand Seq more in depth analysis StrandPhaseR Karen Grimes EMBL Heidelberg GermanyHyobin Jeong Hanyang Universtiy Republic of Korea Ashley Sanders MDC Berlin Germany Thomas Weber EMBL Heidelberg Germany Wolfram Hoeps EMBL Heidelberg GermanyComputer Training Lab17 35 17 50Break 17 50 18 35Lecture remote lecture with Q ADavid Porubsky University of Washington USAFlex Lab A B 18 35 19 05Wrap up and feedbackFlex Lab A B 19 05Departure to Hotel train station 19 15 20 45DinnerISG Hotel Practical information Registration fees and motivation letter The course is limited to 16 participants For selection purposes please note that your application will not be considered without a letter of motivation Registration Registration fees include admission course materials COVID 19 safety measures meals and coffee breaks This EMBO course includes accommodation and transportation to and from the ISG Hotel to the venue Academia 500PhD Student 500Industry 1000 Confirmation and payment The registration fee should be paid only after acceptance to the course The results will be announced approximately 2 3 weeks after the application deadline Motivation letter submission After you have logged in and successfully registered you will receive an email asking you to submit your motivation letter Click on the link provided and enter your motivation letter in the text box provided Alternatively you can submit your motivation letter by clicking on the link on the confirmation page directly after registering Instructions Include your relevant skills experience and qualifications showing why you would be suitable for the course Explain why you would like to attend including what you can contribute and how you think you will benefit from the course Please note The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised For more detailed information follow the instructions provided in our video on how to submit a course motivation letter Further details For further information about registration and motivation letter submission please refer to the FAQ page Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of both registration fee waivers and travel grants Availability is limited to participants attending on site events in Heidelberg and will be indicated during the abstract or motivation letter submission process Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course or conference Travel grant The travel grant will cover the cost of travel airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Course EMBL Conference or EMBO EMBL Symposium from within Europe up to 1000 for participants travelling to an EMBL Course EMBL Conference or EMBO EMBL Symposium from outside Europe up to 500 for any participant travelling to an EMBO Practical Course or EMBO Workshop up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Practical Course or EMBO Workshop Registration fees are only covered for EMBO Practical Courses or EMBO WorkshopsThe organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant EMBO practical courses and workshops only For EMBO Practical Course or EMBO Workshop participants with children there is the possibility to apply for a childcare grant to offset child care costs incurred by participants or speakers when participating at a course or conference Eligible costs include fees for a baby sitter or child care facility travel costs for a care giver or travel costs for taking the child to the meeting etc Please note that priority will be given to early stage researchers A maximum amount of 500 EUR can be awarded per participant applying for an EMBO Childcare Grant In order to apply for this grant for EMBO Workshops you must be registered by the abstract submission deadline Boehringer Ingelheim fonds travel grant Applies to selected courses only Availability will be indicated during the abstract or motivation letter submission process This grant covers costs related to your attendance to the course registration travel and accommodation costs The grant is restricted to PhD students and postdocs who conduct basic biomedical research Whether you are eligible to apply for a travel grant depends on when you received your university entrance qualification e g Abitur A Levels High School Diploma Final State Examination for PhD and MD students as well as graduates the university entrance qualification must not have been obtained more than 11 years ago at the time of the envisaged course for postdocs the university entrance qualification must not have been obtained more than 13 years ago at the time of the envisaged course Application You may apply for financial assistance when submitting your motivation letter for courses and abstract for conferences In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application For the Boehringer Ingelheim Fonds Travel Grant there is a pre application question during the motivation letter submission process and if selected you will be requested to complete a standard form and documentation consisting of your travel expense estimation Selection The scientific organisers will select the recipients of all financial assistance during the motivation letter or abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection is based on your current work or study location the reasons for needing financial support and the impact this event will have on your career Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details View our list of external funding opportunities and information on attending a conference as an event reporter For further information about financial assistance please refer to the FAQ page Accommodation and shuttles Accommodation has been pre booked for you at the ISG Hotel for the default dates of Saturday 12 November to Saturday 19 November 2022 7 nights Please note that the course registration fee includes coverage of accommodation costs in twin rooms including breakfasts for your stay at the ISG If you prefer to stay in a single room please let us know and please note that you will be required to pay an additional cost of 21 EUR per night This should be paid by you directly to the ISG during your stay Any additional nights need to be booked and paid for by you We recommend that all course participants stay at the ISG Hotel which is the dedicated hotel for the course Local transport Shuttle buses will go from the ISG Hotel to EMBL and back mornings and evenings A bus schedule and location of the bus stops will be made available prior to the meeting Further details Address EMBL Heidelberg Meyerhofstra e 1 69117 Heidelberg GermanyFor further information on getting to EMBL Heidelberg visit our Travel Information page For enquiries about accommodation and local transportation please refer to the FAQ page Technical requirements and event software Event software The EMBL eCampus learning platform will be used to collaborate communicate and network with all of the course participants All participants will receive information on how to join shortly before the course We recommend using Chrome Safari or Mozilla Firefox browsers for eCampus Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page COVID 19 related questions COVID 19 information for on site events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage...

Qiaolin Deng, Jan O. Korbel, Anders Ståhlberg, Elisabeth Zielonka

EMBO Practical Course

EMBL Heidelberg

10 November 2022

Edit

November 07, 2022 00:002022ConferenceEMBL Heidelberg, Virtual

Description OverviewSpeakersProgrammePractical informationSponsorsAboutMedia kit Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Please see EMBL s COVID 19 safety policy for testing and other requirements if attending the on site event Symposium overview Neurovascular biology is a young emerging field that aims to unravel the molecular communication between the nervous system and the vasculature Both the nervous system and the vascular system share striking conceptual similarities in the assembly of cellular networks through guided growth and branching processes Vascular and neural cells work together to form a number of functional tissue compartments Endothelial cells certain mural support cells i e pericytes astrocytes and neurons assemble the neurovascular unit which establishes the blood brain and blood retina barriers In fact many of the most debilitating neurodegenerative diseases and cognitive decline involve disruption of the neurovascular unit or compromised vascular function in the nervous system It has become increasingly clear that the endothelium and mural support cells function go beyond nutrient supply and are instructive and structurally required to allow nervous system function In this symposium we bring together researchers from vascular biology and neurobiology to foster interdisciplinary exchange and new emerging concepts on how vascular and nervous systems crosstalk to maintain organ homeostasis and function Session topics Vessel neuronal structureNeurovascular signalingBlood brain barrier Neurovascular couplingGlymphatics Neurovascular pathology Speakers Amparo Acker Palmer Goethe University Frankfurt am Main Germany Ralf H Adams Max Planck Institute for Molecular Biomedicine Germany Katerina Akassoglou University of California San Francisco USA Kari Alitalo University of Helsinki Finland David Attwell University College London UK Serge Charpak Institut de la Vision France Richard Daneman University of California San Diego USA Elga de Vries Amsterdam UMC The Netherlands Virtual Speaker Fiona Doetsch University of Basel Switzerland Anne Eichmann Yale School of Medicine USA Chenghua Gu Harvard Medical School USA Jonathan Kipnis Washington University School of Medicine in St Louis USA Virtual Speaker David Kleinfeld University of California San Diego USA Gou Young Koh Institute for Basic Science Republic of Korea Ferdinand le Noble Karlsruhe Institute of Technology Germany Yoh suke Mukouyama National Heart Lung and Blood Institute USA Simona Parrinello University College London UK Virtual Speaker Christiana Ruhrberg University College London UK Carmen Ruiz de Almod var University of Bonn Germany Andy Shih Seattle Children s Hospital USA Benoit Vanhollebeke University of Brussels Belgium Anju Vasudevan Huntington Medical Research Institutes USA Scientific organisers Amparo Acker Palmer Goethe University Frankfurt am Main Germany Ralf H Adams Max Planck Institute for Molecular Biomedicine Germany Chenghua Gu Harvard Medical School USA Conference organiser Lina Nikolajeva EMBL Heidelberg Germany Programme Got something to say Tweet it EESNeurovascular Please note that due to the ongoing pandemic situation some speakers may need to join virtually to give their talk and the programme is subject to change For registered participants recorded talks will be accessible on demand for 2 weeks after the end of the event unless indicated otherwise Day 1 Monday 7 November 2022 Time Europe Berlin Speaker12 00 13 30Registration and light refreshments13 30 13 40Opening remarks13 40 15 25Session 1 Neurovascular signalingChair Amparo Acker Palmer Goethe University Frankfurt am Main Germany13 40 14 10Molecular regulation of blood brain barrier functionAnne Eichmann Yale School of Medicine USANot available on demand14 10 14 25Short talk Foxf2 maintains brain endothelial cell function via Tie2 signalingMartin Dichgans Ludwig Maximilians University of Munich GermanyNot available on demand14 25 14 40Short talk Vascular guidance configures barrier mesenchymal compartments in the regenerating nerveGanesh Parameshwar Bhat San Raffaele Scientific Institute Italy14 40 14 55Short talk Understanding brain vascular responses to insulinNicole Sumargo University of Tasmania Australia14 55 15 25Function of neuro vascular interactions in organ developmentYoh suke Mukouyama National Heart Lung and Blood Institute USANot available on demand15 25 16 00Coffee break16 00 17 45Session 1 Neurovascular signaling continued Chair Anne Eichmann Yale School of Medicine USA16 00 16 30Cellular and molecular mechanisms controlling artery formation in the CNSRalf H Adams Max Planck Institute for Molecular Biomedicine Germany16 30 16 45Short talk Involvement of JAM C in the interaction between glioblastoma stem like cells and brain endothelial cellsSara Rosinska University of Nantes France16 45 17 00Short talk Premature vascularization of motor neuron columns results in aberrant motor neuron developmentRicardo Vieira Heidelberg University Germany17 00 17 15Short talk Tanycytic VEGF receptor signaling in the blood hypothalamus barrier a new player in the communication between the brain and the peripheryInes Martinez Corral National Institute for Health and Medical Research Inserm FranceNot available on demand17 15 17 45Brain and retina vascularisation in health and diseaseChristiana Ruhrberg University College London United KingdomNot available on demand17 45 19 30Poster session 1 odd numbers Poster numbers19 30 21 00Dinner21 00 22 00After dinner drinks with live music Day 2 Tuesday 8 November 2022 Time Europe Berlin Speaker09 15 10 45Session 2 Brain lymphaticsChair Gou Young Koh Institute for Basic Science Republic of Korea09 15 09 45Virtual talk Neuro immune events at the brain barriersElga de Vries Amsterdam UMC The NetherlandsNot available on demand09 45 10 00Short talk Anatomical diversity of lyve 1 perivascular macrophages distribution in the mouse brainGuy Malkinson Coll ge de France France10 00 10 15Short talk Postnatal development of the neurovascular unit is impaired in Megalencephalic leukoencephalopathy with subcortical cystsMartine Cohen Salmon Coll ge de France France10 15 10 45Towards manipulation of brain lymphatic drainage pathways in CNS diseaseKari Alitalo University of Helsinki FinlandNot available on demand10 45 11 15Coffee break11 15 12 30Session 2 Brain lymphatics continued Chair Kari Alitalo University of Helsinki Finland11 15 11 45Defining vascular heterogeneity at CNS bordersGou Young Koh Center for Vascular Research South Korea11 45 12 00Short talk Blood brain barrier endothelial A20 protects from autoimmune neuroinflammation a novel role for A20 regulated endothelial Icosl in immune cell traffickingLisa Johann Johannes Gutenberg University Mainz Germany12 00 12 30Choroid plexus regulation of adult neural stem cellsFiona Doetsch University of Basel SwitzerlandNot available on demand12 30 14 00Lunch and Meet the speakers with Anne Eichmann Yoh suke Mukouyama Ralf H Adams Christiana Ruhrberg Kari Alitalo Gou Young Koh Fiona Doetsch David Attwell Serge Charpak and Andy Shih14 00 15 30Session 3 Neurovascular couplingChair David Kleinfeld University of California San Diego USA14 00 14 30Immune cell influences on the cerebral microvasculature in Alzheimer s diseaseDavid Attwell University College London UK14 30 14 45Short talk Bidirectional control of neurovascular coupling by pyramidal neuronsBruno Cauli Institute of Biology Paris Seine France14 45 15 00Short talk Engineering approaches to investigate the biophysical role of extracellular matrix in the neurovascular interfaceNicholas Kurniawan Eindhoven University of Technology The Netherlands15 00 15 30The dynamic of brain oxygenation during neurovascular couplingSerge Charpak The Vision Institute FranceNot available on demand15 30 16 00Coffee break16 00 17 45Session 3 Neurovascular coupling continued Chair David Attwell University College London UK16 00 16 30Optical dissection of brain capillary functionAndy Shih Seattle Children s Hospital USA16 30 16 45Short talk Cerebrovascular reactivity to hypercapnia and neurovascular coupling explore different vascular bedsMarine Tournissac The Vision Institute FranceNot available on demand16 45 17 00Short talk Regulation of blood flow patterns by oxytocin neurons through specialized neurovascular coupling dynamicsPreethi Rajamannar Weizmann Institute of Science Israel17 00 17 15Short talk An atlas of the post natal cerebral vasculatureNicolas Renier Paris Brain Institute France17 15 17 45Competing forces shape the spatial pattern of pial vasomotor oscillations across cortexDavid Kleinfeld University of California San Diego USANot available on demand18 00Free evening18 30 20 00Optional Heidelberg Old Town tour with an English speaking tour guide registration required Day 3 Wednesday 9 November 2022 Time Europe Berlin Speaker09 15 10 45Session 4 Blood brain barrierChair Chenghua Gu Harvard Medical School USA09 15 09 45Vascular instructions on neuronal developmentAmparo Acker Palmer Goethe University Frankfurt am Main GermanyNot available on demand09 45 10 00Short talk Development of the intra neural vascularization and physio pathological role of the blood nerve barrierIsabelle Brunet Coll ge de France FranceNot available on demand10 00 10 15Short talk Generating new in vitro 3D blood brain barrier models to better understand cerebral malariaMaria Bernabeu EMBL Barcelona Spain10 15 10 45How does the blood brain barrier regulate brain function and behavior Richard Daneman University of California San Diego USANot available on demand10 45 11 15Coffee break11 15 12 30Session 4 Blood brain barrier continued Chair Richard Daneman University of California San Diego USA11 15 11 45Molecular mechanisms governing the blood brain barrier functionChenghua Gu Harvard Medical School USA11 45 12 00Short talk Optimizing next generation brain delivery platforms with in vitro blood brain barrier modelsRoberto Villasenor Solorio Roche Innovation Center Switzerland12 00 12 30Mechanisms of neurovascular Wnt signalingBenoit Vanhollebeke University of Brussels BelgiumNot available on demand12 30 14 00Lunch and Meet the speakers with David Kleinfeld Amparo Acker Palmer Richard Daneman Chenghua Gu Benoit Vanhollebeke Katerina Akassoglou Anju Vasudevan Carmen Ruiz de Almodovar and Ferdinand le Noble14 00 15 30Session 5 Neurovascular pathologyChair Benoit Vanhollebeke University of Brussels Belgium14 00 14 30The immunology of blood unlocking the drivers for neurodegenerationKaterina Akassoglou University of California San Francisco USANot available on demand14 30 14 45Short talk Exploring the role of FOXF2 in Small vessel disease SVD in a novel human iPSC derived model of the neurovascular unit NVU Dominik Paquet Ludwig Maximilians University of Munich GermanyNot available on demand14 45 15 00Short talk Modeling ischemic stroke in a triculture neurovascular unit on a chipArya Lekshmi Nair Mimetas Amsterdam UMC The Netherlands15 00 15 30Virtual talk Parenchymal Border macrophages regulate CSF flowJonathan Kipnis Washington University School of Medicine in St Louis USA15 30 16 00Coffee break16 00 17 15Session 5 Neurovascular pathology continued Chair Katerina Akassoglou University of California San Francisco USA16 00 16 30The vascular origins of mental illness and new treatment strategiesAnju Vasudevan Huntington Medical Research Institutes HMRI USA16 30 16 45Short talk Machine learning analysis of whole mouse brain vasculature to study neurovascular diseasesMihail Todorov Ludwig Maximilians University of Munich Germany16 45 17 15Virtual talk Glioblastoma invasion injury and neurodevelopmental programmes converge at the perivascular nicheSimona Parrinello University College London UKNot available on demand17 15 19 00Poster session 2 even numbers Poster numbers19 00 21 00Conference dinner21 00 22 30Social event science pub quiz Day 4 Thursday 10 November 2022 Time Europe Berlin Speaker09 15 10 15Session 6 Vessel neuronal structureChair Ralf H Adams Max Planck Institute for Molecular Biomedicine Germany09 15 09 45Blood vessels and neural cells in the CNS interactions and molecular crosstalkCarmen Ruiz de Almodovar University of Bonn GermanyNot available on demand09 45 10 00Short talk Push pull signals from motor axons direct endothelial remodeling to ensure assembly of neuromuscular connectivityDario Bonanomi San Raffaele Scientific Institute Italy10 00 10 15Short talk Perivascular neurons direct three dimensional vascular scaffold formation via piezo2 mediated contactXin Duan University of California San Francisco USANot available on demand10 15 10 45Coffee break10 45 12 00Session 6 Vessel neuronal structure continued Chair Ralf H Adams Max Planck Institute for Molecular Biomedicine Germany10 45 11 00Short talk Vascular Wnt5A orchestrates cerebellar neuronal architecture and circuitryMarta Parrilla Monge Goethe University Frankfurt am Main GermanyNot available on demand11 00 11 15Short talk Obesity as new platform to study neurovascular topologyMarc Schneeberger Pane Yale University USA11 15 11 45Organotypical features of spinal cord vascularisation and repairFerdinand le Noble Karlsruher Institut f r Technologie GermanyNot available on demand11 45 12 00Closing remarks and poster prize12 15Packed lunch and departure12 30 Bus to ISG Hotel and hotels downtown12 45Optional Shuttle bus to Frankfurt Airport Terminal 1 Tickets can be purchased during the conference for 25 EUR with credit card only Practical information Registration fees and abstract submission On site registration fees include admission conference materials COVID 19 safety measures meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Virtual registration fees include access to all of the talks livestreamed and on demand and facility to submit questions On site Academia 700On site PhD Student 600On site Industry 900Virtual Academia 175Virtual PhD Student 125Virtual Industry 225 NO visa support letters will be issued until payment of the registration fee is confirmed Accredited journalists may be eligible to register for complimentary press registration Registrants may be required to provide accreditation or equivalent proof of press membership after registration Please contact Lina Nikolajeva for more information Please note that we do not offer complimentary registrations for editors of scientific journals Confirmation and payment Registration will be on a first come first served basis Your place can only be confirmed after payment of the registration fee If you are added to our waiting list please consider taking advantage of our offerings to participate virtually On site participants Types of payments accepted are international bank transfers and credit card payments Virtual participants We are only able to accept card payments In exceptional cases we can accept bank transfers Please contact events embl de for details Abstract submission Only registered participants attending the on site event are eligible to submit an abstract Abstracts will not be accepted from virtual participants After you have logged in and successfully registered you will receive an email asking you to submit your abstract Click on the link provided and enter your abstract in the text box provided Alternatively you can submit your abstract by clicking on the link on the confirmation page directly after registering The same login credentials are used for both processes Please note Title The title should not exceed 20 words Only the first word of the title should start with a capital letter and the rest of the title should be in lowercase Authors and affiliations Please fill in the author s details as requested in the online form The compulsory details are First Name Last Name Organisation Name Affiliation or Company Country and Email Mark only one author as the role of First author and please don t forget to indicate who will be presenting The order of the authors will be listed as follows First Author Co First Author alphabetically if multiple co author s in the order added by the submitter Presentation types When submitting your abstract you can apply for an oral or poster presentation A selection process will take place with the results announced 2 3 weeks after the abstract submission deadline Please check our FAQs pages for further information on how to submit an abstract Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of both registration fee waivers and travel grants Availability is limited to participants attending on site events in Heidelberg and will be indicated during the abstract or motivation letter submission process Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course or conference Travel grant The travel grant will cover the cost of travel airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Course EMBL Conference or EMBO EMBL Symposium from within Europe up to 1000 for participants travelling to an EMBL Course EMBL Conference or EMBO EMBL Symposium from outside Europe up to 500 for any participant travelling to an EMBO Practical Course or EMBO Workshop up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Practical Course or EMBO Workshop Registration fees are only covered for EMBO Practical Courses or EMBO WorkshopsThe organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Application You may apply for financial assistance when submitting your abstract for conferences In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Selection The scientific organisers will select the recipients of all financial assistance during the motivation letter or abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection is based on your current work or study location the reasons for needing financial support and the impact this event will have on your career Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details See our list of external funding opportunities and information on attending a conference as an event reporter For further information about financial assistance please refer to the FAQ page Accommodation and shuttles Accommodation is not included in the conference registration fee As further changes in our events are possible due to COVID 19 you should book flights trains and hotels with flexible options and favourable cancellation conditions The hotels below have rooms on hold for participants until 6 October 2022 in some cases at special rates Please quote the booking code EES22 11 and confirm the exact price of the room with the hotel directly Hotel AnlageHotel ibis HeidelbergPremier Inn Heidelberg CityHotel Bayrischer Hof ISG Hotel Staycity Aparthotel HeidelbergB B HotelLeonardo Hotel Heidelberg City CentreSteffi s Hostel HeidelbergExzellenz Hotel Boarding HouseMeininger HeidelbergHotel Vier Jahreszeiten HeidelbergHotel Holl nder Hof Hotel Monpti Conference shuttle buses Conference shuttle buses are free of charge for participants and depart from designated bus stops near the hotels to EMBL and back mornings and evenings Download the conference bus schedule here The bus stops for this conference are Star Inn Hotel close to B B Hotel and Main Train Station Kurf rsten Anlage close to Main Train Station Leonardo Hotel City Centre Bergheimer Strasse Neckarm nzplatzPeterskircheISG Hotel View Conference shuttle bus stops and hotels in a larger map Please note that not every bus stop will be used for every event Further details Address EMBL Meyerhofstra e 1 69117 Heidelberg Germany For further information on getting to EMBL Heidelberg visit Public Transportation to the Venue For information about accommodation and local transportation please refer to the FAQ page On site information Catering All meals and coffee breaks are included in the registration fee Our catering staff will prepare a wide variety of vegetarian meals meat and fish dishes soups pasta fresh fruit and vegetables as well as a variety of desserts Please wear your badge at all times when serving yourself No food or drinks are allowed in the auditorium Charging lockers There are lockers available next to the stairs leading down into the Auditorium You will find some of those equipped with sockets to charge your smartphone tablet etc Electricity and charging station In most places the electricity is 220 volts AC 50 cycles An adaptor and a plug that fits the German socket may be needed for your appliances laptop i e American Japanese etc A USB charging station for electronic devices is available at the registration desk EMBL merchandise EMBL Merchandise is available on Mon Thu 9 am 12 pm If you are interested in purchasing an EMBL souvenir products presented in the glass display in the registration area please ask at the registration desk for more information Health and safety notes Please read EMBL s COVID 19 safety policy for on site events Do not smoke in any EMBL building Eating and drinking is prohibited in the Auditorium and all laboratories Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required The first aid room is located next to the ATC Registration Desk room 10 205 Dial the Emergency number 222 from any EMBL internal phone only Where is the accident What happened How many injured Emergency number 06221 387 7821 from mobile phones Please report all accidents to the conference officer at the registration desk In case of fire Press the nearest fire alarm button or the Emergency number 222 from any internal phone A loud fire alarm will go off if an evacuation is required On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting pointsDo not use the lifts Beyond first aid Please remember to bring your own medication if needed to the conference Note that the next pharmacy is a 4 minute drive from the EMBL but for many medications you will be required to see a doctor to get a prescription Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg In any case the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary Internet Wi Fi is available everywhere on the premises no password required just log on to ATC Guest The eduroam network secure world wide roaming access service developed for the international research and education community is also available Lost and found Lost and Found are kept at the registration desk until the end of the conference Luggage There are lockers available on site to store your luggage which require a 2 EURO coin to operate There is another luggage room on level E0 which is free to use but remains unlocked during the conference Nursing room There is a nursing room available in the ATC Rooftop Lounge on level A29 Photography During the conference an EMBL Photographer may be taking photographs If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Printing We can help printing your boarding passes train ticket Please send it to events embl de and collect your print outs at the registration desk Room for prayer yoga and meditation There is a room for prayer mediation and yoga located on level E0 behind the Auditorium Please be respectful of other participants using the room Sightseeing A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing Travel to and from the venue During the event we provide conference shuttle buses to and from EMBL In addition there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time Information on the conference shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page Useful German expressions EnglishGermanHelloHalloGoodbyeAuf WiedersehenGood morningGuten MorgenGood afternoonGuten TagGood eveningGuten AbendGood nightGute NachtI m sorryTut mir leidExcuse me Entschuldigen SieHow are you Wie geht s I m fine thanks And you Mir geht es gut danke und dir Ihnen What is your nameWie heisst du Wie heissen Sie My name isIch heisseDo you speak EnglishSprechen Sie Englisch I don t understandIch verstehe nichtPlease speak more slowlyK nnen Sie bitte langsamer sprechenThank youDanke sch nWhere is the toilet Wo ist die Toilette Please call me a taxiBitte rufen Sie mir ein TaxiHow do I get to Wie komme ich zum zur A beer two beers pleaseEin Bier zwei Bier bitteA glass of red white wine pleaseEin Glas Rot Weisswein bitteThe menu pleaseDie Speisekarte bitteIs there a local speciality Gibt es eine Spezialit t aus dieser Gegend I m VegetarianIch bin VegetarierIt was deliciousEs war hervorragendThe bill pleaseDie Rechnung bitteI have a headacheIch habe KopfschmerzenI have a sore throatIch habe HalsschmerzenMy stomach hurtsIch habe MagenschmerzenI m allergic toIch bin allergisch gegenI need a doctor who speaks EnglishGibt es einen Arzt der Englisch spricht Virtual participation What s included Access to all the livestreamed talksVideo library of the recorded talks during and after the eventFacility to submit questions Please note that only on site participants are able to submit abstracts and participate in the poster sessions Event platform We are using an event platform for this conference More information about the platform will be shared ahead of the conference Guidelines Do not broadcast the conference to unregistered participants You are encouraged to tweet and post about the event Tweet unless the speaker specifically says otherwise but be mindful of unpublished data Please do not capture transmit or redistribute data presented at the meeting Additional information can be found in our Code of Conduct Health and well being It is important to stay healthy and move around especially when you are attending an event virtually We have put together a few coffee break stretches and yoga videos in the conference platform for you to enjoy during the event How to ask questions Please use the Q A function in the event platform If you have any other questions you can go to the Help Desk in the event platform Click on more on the top menu and click Help Desk Time zone The programme is planned based on the Europe Berlin time zone unless otherwise stated Please take your time zone into consideration when planning your attendance Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page COVID 19 related questions COVID 19 information for on site events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Bronze sponsor Media partners EMBO Journal an EMBO Press journal International Union of Biochemistry and Molecular Biology Open Biology a Royal Society journal Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage About EMBO EMBL Symposia promote scientific communication and collaboration in the European research area They provide scientists with a platform to discuss and exchange ideas on forward looking topics and new developments in the life sciences Topics emphasise upcoming developments and the interdisciplinary nature of related fields Jointly funded and organised by EMBO and EMBL and complementary to their respective courses workshops and conference programmes the symposia promote scientific communication and collaboration All symposia are held in the EMBL Advanced Training Centre ATC in Heidelberg Germany or virtually Media kit Want to let others know you re attending this event Take a look at our shareable media and feel free to use them in your social media channels or presentations Social 1080 1920 Social 1080 1080 Social 1600 900 PPT Slide 16 9 Leaderboard 729 90...

Amparo Acker-Palmer, Ralf Adams, Chenghua Gu

EMBO | EMBL Symposium

EMBL Heidelberg, Virtual

6 November - 13 November 2022

Practical integrative structural biology

Edit

November 06, 2022 00:002022CourseEMBL Hamburg

Description Tab 1 Tab 1...

EMBO Practical Course

EMBL Hamburg

2 November 2022

Finding and using publicly available data Q&A session

Edit

November 02, 2022 15:302022WebinarVirtual

Description This Q A question and answer webinar will provide an opportunity for anyone who has completed Finding and using publicly available data A curated set of online courses to join some of EMBL EBI s experts and ask their own questions This session will focus on biocuration open data and accessing publicly available data The questions covered during the Q A webinar will depend on those asked by attendees however we will likely cover topics such as Data sharing and submission Restricted access to genetic phenotypic and clinical data Data management of biological data and open data Finding the right EMBL EBI resource for accessing data...

Virtual

31 October - 4 November 2022

Genome-resolved metagenomics bioinformatics

Edit

October 31, 2022 00:002022CourseVirtual

Description Learn about the tools processes and analysis approaches used in the field of genome resolved metagenomics This course will cover the use of publicly available resources to manage share analyse and interpret metagenomics data focussing primarily on assembly based approaches The virtually delivered content will involve participants learning via pre recorded lectures and live presentations followed by live Q As with the trainers Practical experience will be developed in group activities and in computational exercises run using containerised tools on our virtual training infrastructure Participants will need to be available between the hours of 09 00 17 00 GMT each day of the course...

Shereen Pethania

Virtual

30 October - 4 November 2022

The fundamentals of high-end cell sorting

Edit

October 30, 2022 00:002022CourseEMBL Heidelberg

Description OverviewSpeakers ProgrammePractical informationSponsors Overview Please see EMBL s COVID 19 safety policy for testing and other requirements to attend this on site course Course overview This course includes a robust theoretical part on the fundamentals of cell sorting delivered by world leading experts and practical sessions on using standard cuvette sorters In addition the course program will include principles applications and hands on sessions on Image Cell Sorting ICS allowing attendees to get in touch with this exciting technology Audience The course is intended for Ph D students and postdocs who are starting to use or already using cell sorting in their research projects Applicants with previous active knowledge of basic principles of flow cytometry and regular use of flow cytometers in daily research will profit most from the course content Modules resources The topics that will be covered include instrument set up and validation correct operation to avoid technical insufficiency sample quality the essentials of gating performing single cell sorts for sequencing and sorting based on morphological traits The course will provide knowledge transfer from EMBLs Gene Core regarding single cell genomics Our main goal is to provide our attendees with the proper knowledge and experience about cell sorting so that they can go back to their research with high confidence about their sorts Learning outcomes The principle objectives are to deliver the theory of cell sorting and the practical sides of this high end technology This course is kindly supported by The Flow Cytometry Core Facility at EMBL Heidelberg Speakers Speakers trainers and staff Vladimir Benes EMBL Heidelberg Germany Michael Bonadonna EMBL Heidelberg Germany Joana Cerveira University of Cambridge UK Cora Chadick Amsterdam UMC location VUmc The Netherlands Derek Davies The Francis Crick Institute UK Gelo dela Cruz Novo Nordisk Foundation Center for Stem Cell Medicine reNEW Denmark Daniel Gimenes EMBL Heidelberg Germany Christopher Hall Babraham Institute UK Terra Kuhn EMBL Heidelberg Germany Aaron Middlebrook BD Biosciences USA Diana Ordonez EMBL Heidelberg Germany Malte Paulsen Novo Nordisk Foundation Center for Stem Cell Medicine reNEW Denmark Beata Ramasz EMBL Heidelberg Germany Steffen Schmitt German Cancer Research Center DKFZ Germany Scientific Organisers Derek Davies The Francis Crick Institute UK Andrew Filby Newcastle University UK Diana Ordonez EMBL Heidelberg Germany Malte Paulsen Novo Nordisk Foundation Center for Stem Cell Medicine reNEW Denmark Steffen Schmitt German Cancer Research Center DKFZ Germany Rachael Walker Babraham Institute UK Course Organisers Maria Mercedes Bacadare Goitia Course and Conference Manager EMBL Heidelberg Germany Yvonne Yeboah Training Laboratory Manager EMBL Heidelberg Germany Programme Got something to say Tweet it EMBOCellSort Some pre course work such as watching pre recordings protocol reading and computational exercises with estimated time 0 10 hours will be required and will be shared in advance of the course Some speakers may need to join virtually to give their lecture or Q A and the programme is subject to change Day 1 Sunday 30 October 2022 Time Europe Belin SpeakerLocation08 40 08 55Bus from hotel to EMBL ATC EntranceISG Hotel08 55 09 10RegistrationFlex Lab A B09 10 09 55Welcome house notes and course overview and Safety OverviewFlex Lab A B09 55 10 30FlashtalksFlex Lab A B10 30 11 00Coffee breakFlex Lab A B11 00 11 45Lecture Fluidics and opticsGelo de la cruz Novo Nordisk Foundation Center for Stem Cell Medicine reNEW DenmarkFlex Lab A B11 45 12 30Lecture Signal GenerationMalte Paulsen Novo Nordisk Foundation Center for Stem Cell Medicine reNEW DenmarkFlex Lab A B12 30 13 30LunchCanteen13 30 14 15Lecture Stream Nozzles DropsDerek Davies Newcastle University UKFlex Lab A B14 15 15 00Lecture Drop DelayJoana Cerveira Cambridge University UKFlex Lab A B15 00 16 30Poster session 1 odd numbers and coffee break16 30 18 30Practical sessionGroup 1 Drop delay and RmaxGroup 2 Laser alignmentAll InstructorsTraining Lab B18 30 18 45Departure to HotelEMBL Bus Stop ATC Entrance18 45 19 45DinnerISG Hotel Day 2 Monday 31 October 2022 Time Europe Belin SpeakerLocation08 40 08 55Bus from hotel to EMBL ATC EntranceISG Hotel09 05 09 15Overview of the dayFlex Lab A B09 15 10 00Lecture Cell Sorting ApplicationsMichael Bonadonna EMBL Heidelberg GermanyFlex Lab A B10 00 10 45Lecture Sample Quality ImpactChristopher Hall Babraham Institute Cambridge University UKFlex Lab A B10 45 11 15BreakFlex Lab A B11 15 12 30Lecture The essentials of gating FMO and gating controlsBeata Ramasz EMBL Heidelberg GermanyFlex Lab A B12 30 13 30LunchEMBL Canteen13 30 14 15Lecture Cell Sorting SystemsDiana Ordonez EMBL Heidelberg GermanyFlex Lab A B14 15 15 00Lecture Sorting modes and Index cell sortingDaniel Gimenes EMBL Heidelberg GermanyFlex Lab A B15 00 16 30Poster session 2 even numbers and coffee break16 30 18 30Practical sessionGroup 1 Laser alignmentGroup 2 Drop delay and RmaxAll InstructorsTraining Lab B18 30 19 30DinnerEMBL Canteen 19 30 19 45Departure to HotelEMBL Bus Stop ATC Entrance Day 3 Tuesday 1 November 2022 Time Europe Belin SpeakerLocation08 40 08 55Bus from hotel to EMBL ATC EntranceISG Hotel09 05 09 15Overview of the day09 15 10 15Lecture Image cell sortingAaron Middlebrook BD Biosciences USAFlex Lab A B10 15 11 00Coffee break and transfers to DKFZ11 00 12 30Practical Session Running Different Sorter TypesGroup 1 Image cell sorter EMBL Group 2 Aria Fusion EMBL Group 3 Aria Fusion DKFZ Training Lab B12 30 13 30Group LunchEMBL DKFZ Canteen13 30 18 30Practical Session Running Different Sorter TypesGroup 1 Image cell sorter EMBL Group 2 Aria Fusion EMBL Group 3 Aria Fusion DKFZ Training Lab B18 30Free evening18 30 Departure to ISG Hotel DowntownEMBL Bus Stop ATC Entrance Day 4 Wednesday 2 November 2022 Time Europe Belin SpeakerLocation08 40 08 55Bus from hotel to EMBL ATC EntranceISG Hotel09 05 09 15Overview of the dayFlex Lab A B09 15 10 00Lecture Quality Single Cell SortsCora Chadick Amsterdam UMC location VUmc The NetherlandsFlex Lab A B10 00 10 45Lecture Single Cell GenomicsVladimir Benes EMBL HeidelbergFlex Lab A B10 45 11 30Coffee break and transfers to DKFZFlex Lab A B11 30 13 00Practical Session Running Different Sorter TypesGroup 1 Aria Fusion DKFZ Group 2 Image cell sorter EMBL Group 3 Aria Fusion EMBL Training Lab B13 00 14 00Group LunchEMBL DKFZ Canteen14 00 18 30Practical Session Running Different Sorter TypesGroup 1 Aria Fusion DKFZ Group 2 Image cell sorter EMBL Group 3 Aria Fusion EMBL Training Lab B18 30Departure to DowntownEMBL Bus Stop ATC Entrance19 00 22 00Dinner and Bowling Day 5 Thursday 3 November 2022 Time Europe Belin SpeakerLocation08 40 08 55Bus from hotel to EMBL ATC EntranceISG Hotel09 05 09 15Overview of the dayFlex Lab A B09 15 10 15Lecture Biosafety ConsiderationsSteffen Schmitt German Cancer Research Center DKFZ GermanyFlex Lab A B10 15 11 00Genomic centre tour single cell genomics workflow11 00 11 30Coffee break and transfers to DKFZFlex Lab A B11 30 13 00Practical Session Running Different Sorter TypesGroup 1 Aria Fusion EMBL Group 2 Aria Fusion DKFZ Group 3 Image cell sorter EMBL Training Lab B13 00 14 00Group LunchEMBL DKFZ Canteen14 00 18 30Practical Session Running Different Sorter TypesGroup 1 Aria Fusion EMBL Group 2 Aria Fusion DKFZ Group 3 Image cell sorter EMBL Training Lab B18 30Departure to Downtown EMBL Bus Stop ATC Entrance19 00Dinner and networking downtown Day 6 Friday 4 November 2022 Time Europe Belin SpeakerLocation08 40 08 55Bus from hotel to EMBL ATC EntranceISG Hotel09 05 09 15Overview of the dayFlex Lab A B09 15 10 30Lecture Tips for publishing high quality cytometry dataDerek Davies The Francis Crick Institute UKFlex Lab A B10 30 11 00Coffee breakFlex Lab A B11 00 12 00Lecture Data analysis Correlating flow and image dataAaron Middlebrook BD Biosciences USA Flex Lab A B12 00 13 00Feedback and discussionFlex Lab A B13 00 13 15Packed lunches and departure Flex Lab A B 13 15 13 15Departure to Heidelberg Train Station and DowntownEMBL Bus Stop ATC Entrance Practical information Registration fees and motivation letter The course is limited to 12 participants For selection purposes please note that your application will not be considered without a letter of motivation Registration Registration fees include admission course materials COVID 19 safety measures meals and coffee breaks This EMBO course includes accommodation and transportation to and from the ISG Hotel to the venue Academia 400PhD Student 400Industry 1000 NO visa support letters will be issued until payment of the registration fee is confirmed Confirmation and payment The registration fee should be paid only after acceptance to the course The results will be announced approximately 2 3 weeks after the application deadline Motivation letter submission After you have logged in and successfully registered you will receive an email asking you to submit your motivation letter Click on the link provided and enter your motivation letter in the text box provided Alternatively you can submit your motivation letter by clicking on the link on the confirmation page directly after registering Instructions Include your relevant skills experience and qualifications showing why you would be suitable for the course Explain why you would like to attend including what you can contribute and how you think you will benefit from the course Please note The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised For detailed instructions please watch our video on how to submit a course motivation letter Further details For further information about registration and motivation letter submission please refer to the FAQ page Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of both registration fee waivers and travel grants Availability is limited to participants attending on site events in Heidelberg and will be indicated during the abstract or motivation letter submission process Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course or conference Travel grant The travel grant will cover the cost of travel airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Course EMBL Conference or EMBO EMBL Symposium from within Europe up to 1000 for participants travelling to an EMBL Course EMBL Conference or EMBO EMBL Symposium from outside Europe up to 500 for any participant travelling to an EMBO Practical Course or EMBO Workshop up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Practical Course or EMBO Workshop Registration fees are only covered for EMBO Practical Courses or EMBO WorkshopsThe organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant EMBO Practical Courses and Workshops only For EMBO Practical Course or EMBO Workshop participants with children there is the possibility to apply for a childcare grant to offset child care costs incurred by participants or speakers when participating at a course or conference Eligible costs include fees for a babysitter or child care facility travel costs for a caregiver or travel costs for taking the child to the meeting etc Please note that priority will be given to early stage researchers A maximum amount of 500 EUR can be awarded per participant applying for an EMBO Childcare Grant In order to apply for this grant for EMBO Workshops you must be registered by the abstract submission deadline Boehringer Ingelheim Fonds travel grant Applies to selected courses only Availability will be indicated during the abstract or motivation letter submission process This grant covers costs related to your attendance at the course registration travel and accommodation costs The grant is restricted to PhD students and postdocs who conduct basic biomedical research Whether you are eligible to apply for a travel grant depends on when you received your university entrance qualification e g Abitur A Levels High School Diploma Final State Examination for PhD and MD students as well as graduates the university entrance qualification must not have been obtained more than 11 years ago at the time of the envisaged course for postdocs the university entrance qualification must not have been obtained more than 13 years ago at the time of the envisaged course Application You may apply for financial assistance when submitting your motivation letter for courses and abstract for conferences In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application For the Boehringer Ingelheim Fonds Travel Grant there is a pre application question during the motivation letter submission process and if selected you will be requested to complete a standard form and documentation consisting of your travel expense estimation Selection The scientific organisers will select the recipients of all financial assistance during the motivation letter or abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection is based on your current work or study location the reasons for needing financial support and the impact this event will have on your career Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details See our list of external funding opportunities and information on attending a conference as an event reporter For further information about financial assistance please refer to the FAQ page Accommodation and shuttles Hotel The registration fee includes accommodation for 6 nights 29 Oct 4 Nov at the ISG Hotel in a single room including breakfast Any additional nights need to be booked and paid for by you to the hotel We recommend that all course participants stay at the ISG Hotel which is the dedicated hotel for the course Local transport Shuttle buses will go from the ISG Hotel to EMBL and back mornings and evenings A bus schedule and location of the bus stops will be made available prior to the meeting Further details Address EMBL Heidelberg Meyerhofstra e 1 69117 Heidelberg GermanyFor further information on getting to EMBL Heidelberg visit our Travel Information page For enquiries about accommodation and local transportation please refer to the FAQ page Event software Event software The EMBL eCampus learning platform will be used to collaborate communicate and network with all of the course participants All participants will receive information on how to join shortly before the course We recommend using Chrome Safari or Mozilla Firefox browsers for eCampus Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page COVID 19 related questions COVID 19 information for on site events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Event Supporter Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage...

Derek Davis, Andrew Filby, Diana Ordoñez-Rueda, Malte Paulsen, Steffen Schmitt

EMBO Practical Course

EMBL Heidelberg

27 October 2022

A guide to UniProt for students

Edit

October 27, 2022 15:002022WebinarVirtual

Paul Denny

Virtual

26 October - 29 October 2022

Plasticity across scales: from molecules to phenotypes

Edit

Introductory bioinformatics Q&A session: proteins and structures

Edit

October 12, 2022 15:302022WebinarVirtual

Description This Q A question and answer webinar will provide an opportunity for anyone who has completed Introductory bioinformatics a curated set of EMBL EBI online courses to join some of EMBL EBI s experts and ask their own questions This session will focus on proteins and structures including the EMBL EBI resources UniProt and PDBe The questions covered during the Q A webinar will depend on those asked by attendees however we will likely cover topics such as Searching for protein sequence and functional information data with UniProt Protein structures with PDBe Data management of biological data and open data Finding the right EMBL EBI resource...

Emily Bowler-Barnett, Anna Swan, Deborah Harrus, David Armstrong

Virtual

12 October - 15 October 2022

The complex life of RNA

Edit

October 12, 2022 00:002022ConferenceEMBL Heidelberg, Virtual

Description OverviewSpeakersProgrammePractical informationSponsorsAboutPre conference workshop Overview Late registration for VIRTUAL participation is possible Please contact Diah Yulianti for more information This conference will take place at EMBL Heidelberg with the option to attend virtually Participants will be requested to show a proof of a negative COVID 19 from a supervised negative antigen PCR COVID 19 test not older than 24 h for antigen and 48 h for PCR tests upon arrival at the venue on the first day only Symposium overview Before the genetic information stored in DNA can be used to direct cell growth and metabolism it has to be transferred into RNA Messenger RNAs mRNAs that code for proteins and noncoding RNAs are key components in the transmission of genetic information in all life forms from viruses to complex mammalian organisms Exciting recent findings now reveal a new layer of information added to RNAs in the form of chemical marks the epitranscriptome that play a critical role in gene expression control Following the great success of the virtual 2020 edition of this long standing symposium we are looking forward to returning to an in person meeting for 2022 bringing together leaders in the RNA field post docs and students with the aim of disseminating and discussing the most recent results The programme will include among others sessions on transcription RNA processing and modification mRNA export and localisation mRNA surveillance and decay translation and the control of mRNA expression by microRNAs Session topics Co transcriptional eventsRNA processing and modificationRNA transport and localisationRNA surveillance and decayTranslationmRNA regulation What past participants say about the symposium The Complex Life of RNA is the key event in RNA biology It is incredibly difficult to represent this complex area of knowledge but the organisers succeeded in decomposing the complexity Alexey Moskovtsev Institute of General Pathology and Pathophysiology Moscow Russia Mind blowing science fresh from the bench and presented by top experts a truly rewarding experience Peer Staehler BASF New Business GmbH Germany While I was at The Complex Life RNA symposium held at EMBL I was able to present my work as a poster to several researchers One such researcher from Norway got interested in my work and offered to host me for a short term in his lab to enhance my current project After several correspondences I was able to design a project that could also potentially start a collaboration between my home lab in India and his lab in Norway I applied for the EMBO STF fellowship and I was successful in securing this grant for my visit to Norway So I believe attending this conference was a great boost for my scientific career Preeti Kute Institute for Stem Cell Biology and Regenerative Medicine India Speakers Keynote speakers Bernd Bukau Center for Molecular Biology of Heidelberg University ZMBH and German Cancer Research Center DKFZ Germany Elena Conti Max Planck Institute of Biochemistry Germany Speakers Stefan Ameres Institute of Molecular Biotechnology Austria Edouard Bertrand Institute of Human Genetics France Florence Besse Institut de Biologie Valrose France Jeffrey A Chao Friedrich Miescher Institute for Biomedical Research Switzerland Marina Chekulaeva Max Delbr ck Center for Molecular Medicine Germany Virtual Speaker Olivier Duss EMBL Heidelberg Germany Stacy Horner Duke University USA Katrin Karbstein UF Scripps Biomedical Research USA Kristen Lynch University of Pennsylvania USA Eva Maria Novoa Pardo Centre for Genomic Regulation Spain Clemens Plaschka Research Institute of Molecular Pathology Austria Karsten Weis ETH Zurich Switzerland Scientific organisers Anne Ephrussi EMBL Heidelberg Germany Wendy V Gilbert Yale University USA Torben Heick Jensen Aarhus University Denmark Ramesh Pillai University of Geneva Switzerland Conference organiser Diah Yulianti EMBL Heidelberg Germany Programme Got something to say Tweet it EESRNA Please note that due to the ongoing pandemic situation some speakers may need to join virtually to give their talk and the programme is subject to change For registered participants recorded talks will be accessible on demand for 2 weeks after the end of the event unless indicated otherwise The programme is subject to change Day 1 Wednesday 12 October 2022 Time Europe Berlin Speaker12 00 14 00Arrival and registration with light refreshments12 30 13 30Pre conference workshop The unbiased characterisation of novel human protein coding genes using Ribosome Profiling by Immagina Biotechnology S r l registration required 14 00 14 15Opening remarks by scientific organisers14 15 15 00Keynote lecture Should it stay or should it go the RNA exosome at the crossroads of RNA processing and decayElena Conti Max Planck Institute of Biochemistry Germany15 00 18 30Session 1 Co transcriptional eventsChairs Reini Luco Institut Curie FranceMichaela M ller McNicoll Goethe University Frankfurt Germany15 00 15 30Real time tracking of transcription translation couplingOlivier Duss EMBL Heidelberg GermanyNot available on demand15 30 15 45Histone H1 regulates non coding RNA turnover on chromatin in a m6A dependent mannerMar a G mez CBMSO CSIC UAM Spain15 45 16 00Understanding the basis of transcription within heterochromatinMaja Gehre Institute of Molecular Biotechnology IMBA AustriaNot available on demand16 00 16 45Coffee break and Meet the speakers with Elena Conti and Olivier Duss16 45 17 00Pol II pausing as a milestone on the road to complex animalsAlexandra Chivu Cornell University USA17 00 17 15Extending the Hox molecular repertoire from transcription to mRNA splicingJulie Carnesecchi Centre National de la Recherche Scientifique CNRS France17 15 17 30A direct interaction between CPF and Pol II links RNA 3 end processing to transcriptionManuel Carminati MRC Laboratory of Molecular Biology UK17 30 17 45U1 snRNP induces a CDK12 dependent checkpoint to protect transcripts from incorrect poly A site usageJens Bohne Hannover Medical School GermanyNot available on demand17 45 18 00Structural basis of non coding roX RNA remodelling during dosage compensationJanosch Hennig EMBL Heidelberg GermanyNot available on demand18 00 18 30Flash talk session 1 2 min 1 slide 49 Maxime Wery 91 Alla Fedorova 93 Sebastian Filbeck 123 Dagmar Klostermeier 127 Pawel Krawczyk 137 Szu Shuo Lee 145 Braulio Martinez 151 Matthias Bastian Miosga 159 Tsimafei Navalayeu 163 Reini LucoNot available on demand18 30 19 30Poster viewing19 30 21 00Dinner in EMBL Canteen21 00 22 30Social event science pub quiz in EMBL Canteen21 00 22 30Social event after dinner drinks in ATC Foyer Day 2 Thursday 13 October 2022 Time Europe Berlin Speaker09 00 12 15Session 2 RNA processing and modificationChairs Aldema Sas Chen Tel Aviv University IsraelSara Zaccara Columbia University USA09 00 09 30Decoding the epitranscriptome at single molecule resolutionEva Maria Novoa Pardo Centre for Genomic Regulation Spain09 30 09 45The novel nuclease complex PUCH processes piRNA 5 ends in C elegansNadezda Podvalnaya IMB Mainz Germany09 45 10 15RNA processing in the human immune systemKristen Lynch University of Pennsylvania USA10 15 10 45Coffee break and Meet the speakers with Eva Maria Novoa Pardo Kristen Lynch and Stacy Horner10 45 11 15RNA modifications at the virus host interfaceStacy Horner Duke University USANot available on demand11 15 11 30Functional splicing network systematic approach towards understanding splicing regulationMalgorzata Ewa Rogalska Centre for Genomic Regulation Spain11 30 11 45Molecular bases of m6A regulation by non canonical readersAndres Ramos University College London UKNot available on demand11 45 12 00The S cerevisiae m6A reader Pho92 promotes timely meiotic recombination by controlling key methylated transcriptsBertrand S raphin Institute of Genetics and Molecular and Cellular Biology IGBMC FranceNot available on demand12 00 12 15Flash talk session 2 2 min 1 slide 153 Miha Modic 171 Marco Payr 183 Diana Ribeiro 189 Julian K nig 211 Komal Soni 217 Xue Strobl 221 Anan TarabiehNot available on demand12 15 13 45Lunch with Meet the editors 12 45 13 30 13 45 15 00Session 2 RNA processing and modification continued Chairs Aldema Sas Chen Tel Aviv University IsraelSara Zaccara Columbia University USA13 45 14 15Mechanism and biology of RNA decayStefan Ameres Institute of Molecular Biotechnology Austria14 15 14 45The YTHDF m6A readers are the key mechanism to dynamically regulate m6A mRNA degradationSara Zaccara Columbia University USANot available on demand14 45 15 00HIV 1 infection affects NAD capping of host cell RNAHana Cahova Institute of Organic Chemistry and Biochemistry of the CAS Czech Republic15 00 15 45Coffee break and Meet the speakers with Stefan Ameres Clemens Plaschka and Florence Besse15 45 17 30Session 3 RNA transport and localisationChairs Ina Huppertz Max Planck Institute for Biology of Ageing GermanySuzan Ruijtenberg Utrecht University The Netherlands15 45 16 15How to recognise and package nuclear mRNAClemens Plaschka Research Institute of Molecular Pathology Austria16 15 16 30Material properties of RNP granules are tuned for their in vivo functionMainak Bose EMBL Heidelberg Germany16 30 16 45Hyperphosphorylation of mRNA decapping enzyme DCAP 2 and scaffold protein interactions govern embryonic mRNP condensatesThomas Duchaine McGill University Canada16 45 17 15Transport and remodeling of RNP granules in the nervous systemFlorence Besse Institut de Biologie Valrose FranceNot available on demand17 15 17 30Flash talk session 3 2 min 1 slide 139 Tina Lence 227 Elise van der Salm 231 Ellen van Vroonhoven 48 Valerie Hilgers 52 Pierre Emmanuel Gleizes 60 Fabien BonneauNot available on demand17 30 19 00Poster session 1 odd List of posters19 00Free evening Day 3 Friday 14 October 2022 Time Europe Berlin Speaker09 00 12 00Session 4 RNA surveillance and decayChairs Niels H Gehring University of Cologne GermanySebastian Falk University of Vienna Austria09 00 09 30Condensation of a nuclear mRNA export factor regulates mRNA transport during stressKarsten Weis ETH Z rich SwitzerlandNot available on demand09 30 09 45Dual agonistic and antagonistic roles of ZC3H18 provides for co activation of distinct nuclear RNA exosome decay pathwaysPatrik Pol k Aarhus University DenmarkNot available on demand09 45 10 00Deadenylation rate does not affect fast RNA degradation in yeastCosmin Saveanu Institut Pasteur France10 00 10 45Coffee break and Meet the speakers with Karsten Weiskindly sponsored by Eclipse Bioinnovations10 45 11 00A novel conditional Smg6 mouse model uncovers the role of NMD in circadian timekeepingDavid Gatfield University of Lausanne Switzerland11 00 11 15Conserved Erh1 protein orchestrates Mmi1 YTH guided multi modal mRNA silencingAuriane Rakitch Universit Grenoble Alpes France11 15 11 45Synonymous codon usage regulates translation initiationOlivia Rissland University of Colorado Anschutz Medical Campus USA11 45 12 00Flash talk session 4 2 min 1 slide 82 Vladimir Despic 96 Erika Girardi 112 Francesco Ielasi 120 Wael Kamel 130 Sabrina Kueckelmann 138 Young suk Lee 146 Santiago Martinez LumbrerasNot available on demand12 00 13 30Lunch13 30 16 30Session 5 TranslationChairs David Gatfield University of Lausanne SwitzerlandOlivia Rissland University of Colorado Anschutz Medical Campus USA13 30 14 00Massively parallel identification of zipcodes in primary cortical neuronsMarina Chekulaeva Max Delbr ck Center for Molecular Medicine Germany Virtual Speaker 14 00 14 15Dynamics of human tRNA repertoires as a function of cell identityLexi Gao Max Planck Institute for Biochemistry Germany14 15 14 30Ribosomal quality control in repeat associated non AUG translation of GC rich repeatsYi Ju Tseng University of Michigan USA14 30 15 15Coffee break and Meet the speakers with Marina Chekulaeva and and Katrin Karbsteinkindly sponsored by Eclipse Bioinnovations15 15 15 45Quality control during ribosome assembly and functionKatrin Karbstein Scripps Research USA15 45 16 00Maximizing therapeutic protein yield through human 5 UTR optimizationCole Lewis Yale University USA16 00 16 15Hypoxic Translation is controlled by 3 UTR and the non canonical Cap binding Factor eIF4EHP in D melanogasterClara Hody Universit Libre de Bruxelles BelgiumNot available on demand16 15 16 30Flash talk session 5 2 min 1 slide 158 Isabel S Naarmann de Vries 184 Nina Ripin 194 Aldema Sas Chen 204 Sahil Sharma 220 Jan Niklas Tants 234 Joseph Waldron 246 Roko ZajaNot available on demand16 30 18 00Poster session 2 even 18 00 20 00Gala dinner in EMBL Canteen20 00 22 00Social event after dinner drinks with live music in ATC Foyer22 00 00 00Social event DJ in ATC Foyer Day 4 Saturday 15 October 2022 Time Europe Berlin Speaker09 30 12 00Session 6 mRNA regulationChairs Ayala Shiber Technion Israel Institute of Technology IsraelJeffrey Chao Friedrich Miescher Institute for Biomedical Research Switzerland09 30 10 00Imaging the life and death of mRNAs in living cellsJeffrey Chao Friedrich Miescher Institute for Biomedical Research Switzerland10 00 10 15Alternative splicing of the stress sensitive regulator CIRBP tilts the cellular response to infection by a bacterial pathogenMorgane Corre cole normale sup rieure PSL France10 15 10 45Deciphering the dynamics of divergent co translational assembly pathwaysAyala Shiber Technion Israel Institute of Technology IsraelNot available on demand10 45 11 15Coffee break and Meet the speakers with Jeffrey A Chao Edouard Bertrand and Bernd Bukau11 15 11 45Single molecule imaging reveals a new mechanism for RNA transport and local translationEdouard Bertrand Institute of Human Genetics France11 45 12 00Mechanism of ribosome associated mRNA degradation in the tubulin autoregulation pathwayMarkus H pfler MRC Laboratory of Molecular Biology UK12 00 12 45Keynote lecture Co translational folding and assembly of newly synthesized proteins revealed by ribosome profilingBernd Bukau Center for Molecular Biology of Heidelberg University ZMBH and German Cancer Research Center DKFZ Germany12 45 13 00Closing remarks13 00Packed lunch and departure14 00Optional Shuttle bus to Frankfurt Airport Terminal 1 Tickets can be purchased during the conference for 25 EUR with credit card only Practical information Registration fees and abstract submission On site registration fees include admission conference materials COVID 19 safety measures meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Virtual registration fees include access to all of the talks livestreamed and on demand and facility to submit questions On site Academia 700On site PhD Student 600On site Industry 900Virtual Academia 175Virtual PhD Student 125Virtual Industry 225 NO visa support letters will be issued until payment of the registration fee is confirmed Accredited journalists may be eligible to register for complimentary press registration Registrants may be required to provide accreditation or equivalent proof of press membership after registration Please contact Diah Yulianti for more information Please note that we do not offer complimentary registrations for editors of scientific journals Confirmation and payment Registration will be on a first come first served basis Your place can only be confirmed after payment of the registration fee If you are added to our waiting list please consider taking advantage of our offerings to participate virtually On site participants Types of payments accepted are international bank transfers and credit card payments Virtual participants We are only able to accept card payments In exceptional cases we can accept bank transfers Please contact events embl de for details Abstract submission Only participants registering to attend the on site event are eligible to submit an abstract Abstracts will not be accepted from virtual participants After registration you can submit your abstract via a separate link that will be provided in the email confirmation Alternatively you can access the link on the confirmation page directly after registering The same login credentials are used for both processes Please note Abstract body The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised Title The title should not exceed 20 words Only the first word of the title should start with a capital letter and the rest should be lowercase Authors and affiliations Please fill in the author s details as requested in the online form The compulsory fields are First Name Last Name Organisation Name Affiliation or Company Country and Email Kindly mark only one author in the role of First Author and please don t forget to indicate who will be the Presenter Please enter your co authors correctly via the system by adding accounts together with their organisation institute Do not copy paste them into the body of the abstract text as they will not be indexed in the abstract book Presentation types When submitting your abstract you can apply for an oral or poster presentation A selection process will take place with the results announced 2 3 weeks after the abstract submission deadline For detailed instructions on how to submit a conference abstract follow the instructions provided in this video Please check our FAQs pages for further information on how to submit an abstract Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of both registration fee waivers and travel grants Availability is limited to participants attending on site events in Heidelberg and will be indicated during the abstract or motivation letter submission process Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course or conference Travel grant The travel grant will cover the cost of travel airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Course EMBL Conference or EMBO EMBL Symposium from within Europe up to 1000 for participants travelling to an EMBL Course EMBL Conference or EMBO EMBL Symposium from outside Europe up to 500 for any participant travelling to an EMBO Practical Course or EMBO Workshop up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Practical Course or EMBO Workshop Registration fees are only covered for EMBO Practical Courses or EMBO WorkshopsThe organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Application You may apply for financial assistance when submitting your motivation letter for courses and abstract for conferences In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Selection The scientific organisers will select the recipients of all financial assistance during the motivation letter or abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection is based on your current work or study location the reasons for needing financial support and the impact this event will have on your career Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details See our list of external funding opportunities and information on attending a conference as an event reporter For further information about financial assistance please refer to the FAQ page Accommodation and shuttles Accommodation is not included in the conference registration fee As further changes in our events are possible due to COVID 19 you should book flights trains and hotels with flexible options and favourable cancellation conditions The hotels below have rooms on hold for participants until Sunday 11 September in some cases at special rates Please quote the booking code EES22 10 and confirm the exact price of the room with the hotel directly Hotel AnlageHotel ibis HeidelbergStaycity Aparthotel HeidelbergHotel Bayrischer Hof ISG Hotel Hotel Vier Jahreszeiten HeidelbergB B HotelLeonardo Hotel Heidelberg City CentreHotel Holl nder Hof Exzellenz Hotel Boarding HouseHotel MonptiPremier Inn Heidelberg City Conference shuttle buses Conference shuttle buses are free of charge for participants and depart from designated bus stops near the hotels to EMBL and back mornings and evenings The bus stops for this conference are Staycity Aparthotel Speyerer Str 7 Kurf rsten Anlage Opposite Main Train Station Premier Inn Kurf rsten Anlage 23 Leonardo Hotel Heidelberg City Center Bergheimer Str 63 Neckarm nzplatz Heidelberg Tourist Information Peterskirche Bus stop ISG Hotel Im Eichwald 19 View Conference shuttle bus stops and hotels in a larger map Please note that not every bus stop will be used for every event Download the conference bus schedule here Further details Address EMBL Meyerhofstra e 1 69117 Heidelberg Germany For further information on getting to EMBL Heidelberg visit Public Transportation to the Venue For information about accommodation and local transportation please refer to the FAQ page On site information Catering All meals and coffee breaks are included in the registration fee Our catering staff will prepare a wide variety of vegetarian meals meat and fish dishes soups pasta fresh fruit and vegetables as well as a variety of desserts Please wear your badge at all times when serving yourself No food or drinks are allowed in the auditorium Charging lockers There are lockers available next to the stairs leading down into the Auditorium You will find some of those equipped with sockets to charge your smartphone tablet etc Electricity and charging station In most places the electricity is 220 volts AC 50 cycles An adaptor and a plug that fits the German socket may be needed for your appliances laptop i e American Japanese etc A USB charging station for electronic devices is available at the registration desk EMBL merchandise If you are interested in purchasing an EMBL souvenir products presented in the glass display in the registration area please ask at the registration desk for more information Health and safety notes Please read EMBL s COVID 19 safety policy for on site events Do not smoke in any EMBL building Eating and drinking is prohibited in the Auditorium and all laboratories Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required The first aid room is located next to the ATC Registration Desk room 10 205 Dial the Emergency number 222 from any EMBL internal phone only Where is the accident What happened How many injured Emergency number 06221 387 7821 from mobile phones Please report all accidents to the conference officer at the registration desk In case of fire Press the nearest fire alarm button or the Emergency number 222 from any internal phone A loud fire alarm will go off if an evacuation is required On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting pointsDo not use the lifts Beyond first aid Please remember to bring your own medication if needed to the conference Note that the next pharmacy is a 4 minute drive from the EMBL but for many medications you will be required to see a doctor to get a prescription Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg In any case the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary Internet Wi Fi is available everywhere on the premises no password required just log on to ATC Guest The eduroam network secure world wide roaming access service developed for the international research and education community is also available Lost and found Lost and Found are kept at the registration desk until the end of the conference Luggage There are lockers available on site to store your luggage which require a 2 EURO coin to operate There is another luggage room on level E0 which is free to use but remains unlocked during the conference Nursing room There is a nursing room available in the ATC Rooftop Lounge on level A29 Photography During the conference an EMBL Photographer may be taking photographs If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Printing We can help printing your boarding passes train ticket Please send it to events embl de and collect your print outs at the registration desk Room for prayer yoga and meditation There is a room for prayer mediation and yoga located on level E0 behind the Auditorium Please be respectful of other participants using the room Sightseeing A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing Travel to and from the venue During the event we provide conference shuttle busses to and from EMBL In addition there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time Information on the conference shuttle busses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page Useful German expressions Where is the nearest Covid test centre Wo ist das n chste Covid Testzentrum HelloHalloGoodbyeAuf WiedersehenGood morningGuten MorgenGood afternoonGuten TagGood eveningGuten AbendGood nightGute NachtI m sorryTut mir leidExcuse me Entschuldigen SieHow are you Wie gehts I m fine thanks And you Mir geht es gut danke und dir Ihnen What is your nameWie heisst du Wie heissen Sie My name isIch heisseDo you speak EnglishSprechen Sie Englisch I don t understandIch verstehe nichtPlease speak more slowlyK nnen Sie bitte langsamer sprechenThank youDankesch nWhere is the toilet Wo ist die Toilette Please call me a taxiBitte rufen Sie mir ein TaxiHow do I get to Wie komme ich zum zur A beer two beers pleaseEin Bier zwei Bier bitteA glass of red white wine pleaseEin Glas Rot Weisswein bitteThe menu pleaseDie Speisekarte bitteIs there a local speciality Gibt es eine Spezialit t aus dieser Gegend I m VegetarianIch bin VegetarierIt was deliciousEs war hervorragendThe bill pleaseDie Rechnung bitteI have a headacheIch habe KopfschmerzenI have a sore throatIch habe HalsschmerzenMy stomach hurtsIch habe MagenschmerzenI m allergic toIch bin allergisch gegenI need a doctor who speaks EnglishGibt es einen Arzt der Englisch spricht Virtual Participation What s included Access to all the livestreamed talksVideo library of the recorded talks during and after the eventFacility to submit questions Please note that only on site participants are able to submit abstracts and participate in the poster sessions Event platform We are using an event platform for this conference More information about the platform will be shared ahead of the conference Guidelines Do not broadcast the conference to unregistered participants You are encouraged to tweet and post about the event Tweet unless the speaker specifically says otherwise but be mindful of unpublished data Please do not capture transmit or redistribute data presented at the meeting Additional information can be found in our Code of Conduct Health and well being It is important to stay healthy and move around especially when you are attending an event virtually We have put together a few coffee break stretches and yoga videos in the conference platform for you to enjoy during the event How to ask questions Please use the Q A function in the event platform If you have any other questions you can go to the Help Desk in the event platform Click on more on the top menu and click Help Desk Time zone The programme is planned based on the Europe Berlin time zone unless otherwise stated Please take your time zone into consideration when planning your attendance Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page COVID 19 related questions COVID 19 information for on site events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Silver sponsor Bronze sponsors Symposium sponsor Media partners EMBO reports an EMBO Press journal International Union of Biochemistry and Molecular Biology Open Biology a Royal Society journal Sponsorship Opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information on sponsoring possibilities If you are interested in becoming a media partner of this event please visit our media partnerships webpage Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsoring embl de About EMBO EMBL Symposia promote scientific communication and collaboration in the European research area They provide scientists with a platform to discuss and exchange ideas on forward looking topics and new developments in the life sciences Topics emphasise upcoming developments and the interdisciplinary nature of related fields Jointly funded and organised by EMBO and EMBL and complementary to their respective courses workshops and conference programmes the symposia promote scientific communication and collaboration All symposia are held in the EMBL Advanced Training Centre ATC in Heidelberg Germany or virtually Pre conference workshop Industry webinar will be hosted by our sponsor Immagina Biotechnology S r l prior to the EMBO EMBL Symposium The complex life of RNA on Wednesday 12 October 2022 12 30 13 30 Participation in this workshop is free of charge for registered conference attendees The number of available places is limited first come first served All registered conference attendees will receive an email with a registration link ABSTRACT The unbiased characterisation of novel human protein coding genes using Ribosome Profiling Speaker Dr Marc Eamonn Healy University of Z rich Carcinogenesis and progression of cancer is fundamentally based on changes to the genome of the tumor cell which results in a decisive growth advantage However those exact genetic changes which lead to faster cell growth can also represent potential targets for molecular therapies Unfortunately for many cancer types the identification of such genes has proven largely unsuccessful In this light it may be time to think outside of the box when it comes identifying potential novel therapeutic targets Over the last number of years it has become clear that mammalian protein coding genomes are incomplete Recently challenges to traditional criteria governing protein annotation have identified thousands of novel protein coding non canonical open reading frames ncORFs which have proven to be essential for a number of critical cellular processes ranging from immunology to cellular survival Our research aims to explore unchartered genetic areas by comprehensively characterising the ncORFs which are indispensable for the survival of non transformed and cancer cells By combining ribosome profiling with loss of function CRISPR Cas9 screening we have the ability to define and characterise the complete protein coding capacity of the human genome in an unbiased manner The emerging field of novel ncORF encoded proteins has the potential to herald a new chapter in cancer research The unbiased identification of a completely new database of functional proteins may potentially uncover missing pieces to currently unanswerable molecular questions in cancer biology...

Anne Ephrussi, Wendy V. Gilbert, Torben Heick Jensen, Ramesh Pillai

EMBO | EMBL Symposium

EMBL Heidelberg, Virtual

11 October 2022

Data protection and security aspects of running simulations on personal data with HPC

Edit

October 11, 2022 15:002022WebinarVirtual

Description When processing health and genetic data in High Performance Computing HPC clusters researchers must consider the application of research ethics principles as well as the General Data Protection Regulation including issues of identifiability duties of confidentiality and security and accountability A Data Protection Impact Assessment can be a useful tool to identify and mitigate any risks to the rights and freedoms of data subjects patients and research participants In this webinar we will also highlight the risks of working with sensitive data on an HPC cluster and we will provide you guidelines and measures that can help you secure your data and its processing Additionally we will give a short overview of what you should look out for when selecting or developing software to work on this data About the speakers Sarah Peter studied Bioinformatics and worked for a few years as a researcher and data manager at the Max Planck Institute Now she works at the Luxembourg Centre for Systems Biomedicine UNILU as an Infrastructure Engineer in the R3 and IT Infrastructure team She is also the liaison for the HPC team Since GDPR has come into effect she spends some of her time doing risk analysis for the institute s IT infrastructure and the HPC cluster Adrian Thorogood is a lawyer and Research Development Specialist in the Bioinformatics Core Luxembourg Centre for Systems Biomedicine UNILU He works with the European 1 Million Genomes Project and other infrastructure projects to address ethical and legal issues that arise when sharing genomic and health related data cross border and internationally His research focuses on how genomic sequencing platforms information and networking technologies open science practices and patient empowerment movements are disrupting research and health care...

Laurence Calzone, Arnau Montagud

Virtual

9 October - 14 October 2022

Genome engineering: CRISPR/Cas from cells to mice

Edit

October 09, 2022 00:002022CourseEMBL Heidelberg

Description OverviewSpeakers trainers and staffProgramme Practical informationSponsors Overview Course overview This course will provide training in genome editing and cell engineering in mammalian cells and mouse embryos using the highly efficient CRISPR Cas9 system Participants will learn design of CRISPR targets using bioinformatics tools generation of gene knock outs knock ins and target validation using the most current technologies The course will be split into two groups mammalian cells OR mice based on participants expertise Please note that all participants are expected to engage in all sessions Particpants should plan for approximately 1 hour extra per day for self paced learning modules Audience This course is aimed at researchers who are familiar with basic molecular and cell biology techniques and who want to learn how to create an engineered mammalian cell line or mouse model using the most recent and advanced CRISPR Cas9 system No previous experience in genome editing is required Modules resources How to create a CRISPR Cas9 experiment using various design toolsTransfection optimisation for efficient gene editingGeneration of knock out and knock in cell lines and mouse embryosValidation of genome edited cell lines and embryos Learning outcomes After this course you should be able to Design a CRISPR based project using editing tools for your target gene of interestChoose the right format of gene editing tool and delivery strategy for your cell type or embryosEdit screen and validate the engineered models embryo manipulation What past participants say about the course An extremely valuable tool for understanding the theoretical bases and practical aspects related to the CrispR technologies Excellent speakers and experts will welcome you and guide you through this course Marco Bruschi Gustave Roussy Cancer Institute France Speakers trainers and staff Antony Adamson The University of Manchester UK Michela Ascolani EMBL Rome Italy Dana Carroll University of Utah School of Medicine USA Isabel Clara Rollan Delgado EMBL Heidelberg Germany Neil Humphreys EMBL Rome Italy Manuel Kaulich Universit tsklinikum Frankfurt Germany Birgit Koch Max Planck Institute for Medical Research Germany Dominik Lindenhofer EMBL Heidelberg Germany Beate Neumann EMBL Heidelberg Germany Alexandre Paix EMBL Heidelberg Germany Kim Remans EMBL Heidelberg Germany Daniel Schraivogel EMBL Heidelberg GErmany Scientific Organisers Neil Humphreys EMBL Rome Italy Birgit Koch Max Planck Institute for Medical Research Germany Representatives from ThermoFisher ThermoFisher Scientific Germany Course Organisers Chris Stocks Course and Conference Team Lead EMBL Heidelberg Germany Yvonne Yeboah Training Laboratory Manager EMBL Heidelberg Germany Swetlana Krez Training Laboratory Technician EMBL Heidelberg Germany Programme Got something to say Tweet it EMBLCRISPRcas Some pre course work such as watching pre recordings protocol reading and computational exercises with estimated time 0 10 hours will be required and will be shared in advance of the course Some speakers may need to join virtually to give their lecture or Q A and the programme is subject to change Day 1 Sunday 9 October 2022 Time Europe Berlin SessionLocation 16 00 16 30 Registration ISG Hotel16 30 17 30Arrival WelcomeIntroduction to course design ISG Seminar room 17 30 18 00IcebreakerISG Seminar room 18 00 19 00Live Keynote Lecture Introduction to CRISPR Cas 9Dana Carroll University of Utah School of Medicine USAThis talk will be remoteISG Seminar room 19 00Dinner Networking ISG Hotel Day 2 Monday 10 October 2022 Time Europe Berlin Session Location08 30 08 45 Bus from ISG Hotel to EMBL ISG Hotel08 45 09 00 RegistrationCourtyard Room09 00 12 15Day 2 Guide RNA Design09 00 09 15Lab SafetyYvonne Yeboah EMBL Heidelberg GermanyCourtyard Room09 15 10 15Lecture Purification of Cas9 protein Kim Remans EMBL Heidelberg Germany Courtyard Room10 15 11 15Practical 1 gRNA Donor designKristof Kersse Thermo Fisher Scientific GermanyKieran Van Kessel Thermo Fisher Scientific UKTraining Lab A B11 15 11 45Coffee 11 45 12 30 Practical in groups11 45 12 30Mammalian Cell GroupPractical 1 1 TrueTag Donor Template Synthesis PCRSilke Deckert Thermo Fisher Scientific Germany Kristof Kersse Thermo Fisher Scientific GermanyAntony Miles Thermo Fisher Scientific UK Kieran Van Kessel Thermo Fisher Scientific UKTraining Lab A 11 45 12 30Mouse Embryo GroupgRNA donor design for embryosNeil Humphreys EMBL Rome ItalyMichela Ascolani EMBL Rome ItalyIsabel Rollan EMBL Heidelberg GermanyTraining Lab B12 30 13 30Lunch 13 30 14 30Lecture Robust genome editing is simple molecular biology application across model organismsAlexandre Paix EMBL Heidelberg Germany Courtyard Room14 30 16 00Practical 1 2Mammalian Cell Group TrueTag Donor Template Synthesis Gel analysis and Clean upSilke Deckert Thermo Fisher Scientific Germany Kristof Kersse Thermo Fisher Scientific GermanyAntony Miles Thermo Fisher Scientific UK Kieran Van Kessel Thermo Fisher Scientific UKTraining Lab A B14 30 16 00Practical 1 2Mouse Embryo Group Basic embryo handling Glass transfer pipet prep harvest embryos and short seminar on embryo transfer and demonstration Neil Humphreys EMBL Rome ItalyMichela Ascolani EMBL Rome ItalyIsabel Rollan EMBL Heidelberg GermanyTraining Lab A B16 00 16 30Coffee 16 30 18 00Practical 2 3Mammalian Cell GroupGroup A gRNA efficiency Lipid transfection of 293FT cells with gRNA and Cas9 protein Lipid transfection of 293FT eBFP cells with gRNA Cas9 protein and ssODNSilke Deckert Thermo Fisher Scientific UK Antony Miles Thermo Fisher Scientific UK Kieran Van Kessel Thermo Fisher Scientific UKGroup B Guide RNA design taskBirgit Koch Max Planck Institute for Medical Research GermanyKristof Kersse Thermo Fisher Scientific GermanyTraining Lab A B16 30 18 00Mouse Embryo Group Annealing gRNAs and microinjection mixes Intro to TLR2 systemNeil Humphreys EMBL Rome ItalyMichela Ascolani EMBL Rome ItalyIsabel Rollan EMBL HeidelbergTraining Lab A B18 00 19 00Dinner 19 00 20 30Practical 2 3Mammalian Cell GroupGroup B gRNA efficiency Lipid transfection of 293FT cells with gRNA and Cas9 protein Lipid transfection of 293FT eBFP cells with gRNA Cas9 protein and ssODN Silke Deckert Thermo Fisher Scientific UK Antony Miles Thermo Fisher Scientific UK Kieran Van Kessel Thermo Fisher Scientific UK Group A Guide RNA design taskBirgit Koch Max Planck Institute for Medical Research GermanyKristof Kersse Thermo Fisher Scientific GermanyTraining Lab A B19 00 20 30Practical 2 3Mouse Embryo GroupEmbryos handling and transfer KSOM media O N cultureNeil Humphreys EMBL Rome ItalyMichela Ascolani EMBL Rome ItalyIsabel Rollan EMBL Heidelberg Germany Training Lab A B20 30Bus from EMBL to ISG Hotel Day 3 Tuesday 11 October 2022 Time Europe Berlin SessionLocation08 30 08 45 Bus from ISG Hotel to EMBL08 45 09 15Registration09 15 10 15Lecture CRISPR Cas genome editing to generate transgenic miceNeil Humphreys EMBL Rome ItalyCourtyard Room10 15 11 15Practical Lecture Mammalian Cell Group Generation and validation of endogenously tagged cell lineBirgit Koch Max Planck Institute for Medical Research Germany Courtyard Room10 15 11 15Practical 4 Mouse Embryo Group Assess and clean up 2 cell microinjected embryosTraining Lab A B11 15 11 45Coffee11 45 12 45Lecture Pooled screening in growth variable human cerebral organoid tissue via DNA barcoding Dominik Lindenhofer EMBL Heidelberg GermanyCourtyard Room12 45 13 45Lunch 13 45 15 45Practical 1 3 4Mammalian Cell GroupGroup A Tag Knock in Electroporation of 293FT with gRNA Cas9 protein and TrueTag donor templateSilke Deckert Thermo Fisher Scientific GermanyKristof Kersse Thermo Fisher Scientific GermanyAntony Miles Thermo Fisher Scientific UK Kieran Van Kessel Thermo Fisher Scientific UKGroup B Project discussionBirgit Koch Max Planck Institute for Medical Research GermanyKristof Kersse Thermo Fisher Scientific GermanyCell Culture Flex LabCourtyard Room13 45 15 45Practical 4Mouse Embryo GroupThaw pre prepared blastocysts assess viability and extract DNANeil Humphreys EMBL Rome ItalyMichela Ascolani EMBL Rome ItalyIsabel Rollan EMBL HeidelbergTraining Lab A B 15 45 16 15Coffee 16 15 18 15Practical 1 3 4Mammalian Cell GroupGroup B Tag Knock in Electroporation of 293FT with gRNA Cas9 protein and TrueTag donor templateSilke Deckert Thermo Fisher Scientific GermanyKristof Kersse Thermo Fisher Scientific GermanyAntony Miles Thermo Fisher Scientific UK Kieran Van Kessel Thermo Fisher Scientific UK Group A Project discussionBirgit Koch Max Planck Institute for Medical Research GermanyKristof Kersse Thermo Fisher Scientific GermanyCell Culture Flex Lab16 15 18 15Practical 5Mouse Embryo GroupDesign cut test PCR and knock in specific PCR forward and reverse Run O NNeil Humphreys EMBL Rome ItalyMichela Ascolani EMBL Rome ItalyIsabel Rollan EMBL Heidelberg Germany Training Lab A B18 15 19 15DinnerCanteen19 15Bus from EMBL to ISG hotelEMBL Bus stop Day 4 Wednesday 12 October 2022 Time Europe Berlin SessionLocation08 30 08 45 Bus from ISG Hotel to EMBL 08 45 09 15Registration Courtyard Room09 15 10 15Lecture Genome scale pooled genetic screens with CRISPR Cas9 and complex readouts from single cellsDaniel Schraivogel EMBL Heidelberg Germany this talk is remote Courtyard Room10 15 12 15Practical in GroupsMammalian Cell Group Practicals 5 1 5 2 GCD Cell Harvest and lysis set up GCD PCRSilke Deckert Thermo Fisher Scientific GermanyAntony Miles Thermo Fisher Scientific UK Training Lab A B 10 15 12 15Mouse Embryo Group Practicals 5 1 5 22Assess and clean up 4 to 8 cell embryos Run Gels for PCRsSet up T7 assay and digestion assay PCRs Neil Humphreys EMBL Rome ItalyMichela Ascolani EMBL Rome ItalyIsabel Rollan EMBL Heidelberg Germany Training Lab A B12 30 13 30Lunch 13 30 14 30Lecture The 3Cs technology for CRISPR gRNA library generationManuel Kaulich Goethe University GermanyCourtyard Room14 30 16 30Practical in GroupsPractical 5 3 Mammalian Cell GroupCR analysis set up GCD re annealing reactionPractical 5 4 5 5Set up digestion for GCD gel purification sample submission for sanger sequencingGel analysis of GCDSilke Deckert Thermo Fisher Scientific GermanyKristof Kersse Thermo Fisher Scientific GermanyAntony Miles Thermo Fisher Scientific UK Kieran Van Kessel Thermo Fisher Scientific UK Flex Lab A B 14 30 16 30Mouse Embryo Group Cut out gels for sequencing and run gels for T7 assay and digestion assay T7 assay and digestion assay analyze submission for sanger sequencingNeil Humphreys EMBL Rome ItalyMichela Ascolani EMBL Rome ItalyTraining Lab A B16 30 17 00Coffee 17 00 18 00Lecture Imaged based high throughput screening RNAi vs CRISPRBeate Neumann EMBL Heidelberg Germany Courtyard Room18 00 19 00DinnerRoof Top Lounge19 00 20 30Discussion round and drinks Ethical issues of CRISPR technology and genome engineeringRoof Top Lounge20 30 Bus from EMBL to ISG hotel EMBL bus stop Day 5 Thursday 13 October 2022 Time Europe Berlin SessionLocation08 30 08 45 Bus from ISG Hotel to EMBL 08 45 09 15Registration 09 15 10 45Practical in GroupsMammalian Cell GroupGroup A Examine BFP cells via microscopy and FACSKristof Kersse Thermo Fisher Scientific GermanyAntony Miles Thermo Fisher Scientific UK Kieran Van Kessel Thermo Fisher Scientific UK Group B Knock In cell validation DNA PreparationBirgit Koch Max Planck Institute for Medical Research Germany Training Lab B09 15 10 45Mouse Embryo GroupThaw TLR2 embryos and examine KO and KI morular blastocysts for florescenceKnock In validation Neil Humphreys EMBL Rome ItalyMichela Ascolani EMBL Rome ItalyTraining Lab B10 45 11 15Coffee and group photo 11 15 12 45Practical in GroupsMammalian Cell GroupGroup B Examine BFP cells via microscopy and FACSAntony Miles Thermo Fisher Scientific UKGroup A Knock In cell validation DNA PreparationBirgit Koch Max Planck Institute for Medical Research GermanyTraining Lab B11 15 12 45Mouse Embryo GroupImage embryosNeil Humphreys EMBL Rome ItalyMichela Ascolani EMBL Rome Italy Training Lab B 12 45 13 45Lunch 13 45 15 00Practical in groupsMammalian cell groupKnock In cell validation Set up Junction PCRBirgit Koch Max Planck Institute for Medical Research GermanyNeil Humphreys EMBL Rome ItalyMichela Ascolani EMBL Rome ItalyTraining Lab B 13 45 15 00 Mouse embryo groupTour of LAR Facility 15 00 15 15Break 15 15 17 40Technology Lounge Genome modification technologiesPresentation by different companies Click here for the Technology Lounge schedule A01 StillaA23 MerckB11 IDTFlex Lab ThermoFisherRoof Top Lounge NEB17 40Bus from EMBL to downtown via ISG Hotel ATC entrance19 00Downtown course dinnerOskars Downtown Day 6 Friday 14 October 2022 Time Europe Berlin SessionLocation08 30 08 45 Bus from ISG Hotel to EMBL ISG Hotel08 45 09 15RegistrationFlex Lab09 15 10 15Lecture Gene editing in different experimental models Antony Adamson The University of Manchester UKFlex Lab A B 10 15 11 15Practical in GroupsMammalian Cell GroupGel electrophoresis of junction PCRBirgit Koch Max Planck Institute for Medical Research GermanyTraining Lab B10 15 11 15Mouse Embryo GroupProject discussionNeil Humphreys EMBL Rome ItalyMichela Ascolani EMBL Rome ItalyFlex Lab A B11 15 11 45Break11 45 12 45Practical in GroupsMammalian Cell GroupAnalysis of gel electrophoresisBirgit Koch Max Planck Institute for Medical Research GermanyTraining Lab B11 45 12 45Mouse Embryo GroupProject discussionNeil Humphreys EMBL Rome ItalyMichela Ascolani EMBL Rome ItalyFlex Lab A B12 45 13 45Lunch13 45 15 00The Solution Room Last chance to ask questions Flex Lab A B 15 00 15 30Final discussions feedback session Flex Lab A B Practical information Registration fees and motivation letter The course is limited to 16 participants For selection purposes please note that your application will not be considered without a letter of motivation Registration Registration fees include admission course materials COVID 19 safety measures meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Academia 790PhD Student 790Industry 1200 NO visa support letters will be issued until payment of the registration fee is confirmed Confirmation and payment The registration fee should be paid only after acceptance to the course The results will be announced approximately 2 3 weeks after the application deadline Motivation letter submission After you have logged in and successfully registered you will receive an email asking you to submit your motivation letter Click on the link provided and enter your motivation letter in the text box provided Alternatively you can submit your motivation letter by clicking on the link on the confirmation page directly after registering Instructions Include your relevant skills experience and qualifications showing why you would be suitable for the course Explain why you would like to attend including what you can contribute and how you think you will benefit from the course Please note The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised For detailed instructions please watch our video on how to submit a course motivation letter Further details For further information about registration and motivation letter submission please refer to the FAQ page Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of both registration fee waivers and travel grants Availability is limited to participants attending on site events in Heidelberg and will be indicated during the abstract or motivation letter submission process Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course or conference Travel grant The travel grant will cover the cost of travel airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Course EMBL Conference or EMBO EMBL Symposium from within Europe up to 1000 for participants travelling to an EMBL Course EMBL Conference or EMBO EMBL Symposium from outside Europe up to 500 for any participant travelling to an EMBO Practical Course or EMBO Workshop up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Practical Course or EMBO Workshop Registration fees are only covered for EMBO Practical Courses or EMBO WorkshopsThe organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant EMBO practical courses and workshops only For EMBO Practical Course or EMBO Workshop participants with children there is the possibility to apply for a childcare grant to offset child care costs incurred by participants or speakers when participating at a course or conference Eligible costs include fees for a babysitter or child care facility travel costs for a caregiver or travel costs for taking the child to the meeting etc Please note that priority will be given to early stage researchers A maximum amount of 500 EUR can be awarded per participant applying for an EMBO Childcare Grant In order to apply for this grant for EMBO Workshops you must be registered by the abstract submission deadline Boehringer ingelheim fonds travel grant Applies to selected courses only Availability will be indicated during the abstract or motivation letter submission process This grant covers costs related to your attendance at the course registration travel and accommodation costs The grant is restricted to PhD students and postdocs who conduct basic biomedical research Whether you are eligible to apply for a travel grant depends on when you received your university entrance qualification e g Abitur A Levels High School Diploma Final State Examination for PhD and MD students as well as graduates the university entrance qualification must not have been obtained more than 11 years ago at the time of the envisaged course for postdocs the university entrance qualification must not have been obtained more than 13 years ago at the time of the envisaged course Application You may apply for financial assistance when submitting your motivation letter for courses and abstract for conferences In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application For the Boehringer Ingelheim Fonds Travel Grant there is a pre application question during the motivation letter submission process and if selected you will be requested to complete a standard form and documentation consisting of your travel expense estimation Selection The scientific organisers will select the recipients of all financial assistance during the motivation letter or abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection is based on your current work or study location the reasons for needing financial support and the impact this event will have on your career Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details See our list of external funding opportunities and information on attending a conference as an event reporter For further information about financial assistance please refer to the FAQ page Accommodation and shuttles Hotel Single rooms have been reserved for 5 nights 09 13 October 2022 at the ISG Hotel After the selection process selected participants should contact the hotel directly to make a booking booking code GEE22 01 We recommend that all course participants stay at the ISG Hotel which is the dedicated hotel for the course Local transport Shuttle buses will go from the ISG Hotel to EMBL and back mornings and evenings A bus schedule and location of the bus stops will be made available prior to the meeting Further details Address EMBL Heidelberg Meyerhofstra e 1 69117 Heidelberg GermanyFor further information on getting to EMBL Heidelberg visit our Travel Information page For enquiries about accommodation and local transportation please refer to the FAQ page Event software Event software The EMBL eCampus learning platform will be used to collaborate communicate and network with all of the course participants All participants will receive information on how to join shortly before the course We recommend using Chrome Safari or Mozilla Firefox browsers for eCampus Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page COVID 19 related questions COVID 19 information for on site events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage...

N. Humphreys, B. Koch, P. Rajakannu, E. Zielonka

EMBL Course

EMBL Heidelberg

5 October 2022

Introductory bioinformatics Q&A session: genes and gene expression

Edit

October 05, 2022 15:302022WebinarVirtual

Description This Q A question and answer webinar will provide an opportunity for anyone who has completed Introductory bioinformatics a curated set of EMBL EBI online courses to join some of EMBL EBI s experts and ask their own questions This session will focus on genes and gene expression including the EMBL EBI resources Ensembl and Expression Atlas The questions covered during the Q A webinar will depend on those asked by attendees however we will likely cover topics such as Browsing genomes with Ensembl Discovering gene expression data with Expression Atlas Data management of biological data and open data Finding the right EMBL EBI resource...

Aleena Mushtaq, Sarah Morgan, Nancy George, Benjamin Moore, Anja Fullgrabe, Louisse Paola Mirabueno

Virtual

5 October - 8 October 2022

Molecular mechanisms in evolution and ecology

Edit

October 05, 2022 00:002022ConferenceEMBL Heidelberg, Virtual

Description OverviewSpeakersProgrammePractical informationSponsors Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Proof of COVID 19 vaccination or recovery is required for on site attendance Please see EMBL s COVID 19 safety policy for on site events For late registrations to attend the workshop onsite please contact Raili Pall Conference overview This conference series has become known for exploring yeasts as models to study questions of general relevance to evolution and ecology Experts will speak on a range of topics including evolution theory ecology genetics cell biology genomics systems biology metabolic modelling and engineering The focus of this conference will be on comparative and experimental strategies to explore evolutionary questions from field studies to computer simulations to comparative genomics Central evolutionary questions will be discussed using yeast and a range of other species whose biology is well understood and to determine the degree to which that biology is conserved in more distantly related species The aim is to move from correlative studies based on comparative work to more causal studies based on broad experimental support This problem is particularly pressing in the age of cheap and easy sequencing Session topics Experimental evolutionGenomic insights in ecology evolutionSystems and synthetic biologyAssembly and evolution of communitiesUnderstanding predicting evolution What past participants say about the conference An incredibly interesting and well organised event not only from the scientific side but also on the technical part As expected from other editions of the meeting the science was amazing and very variegated Kudos for the organisation and for the unusually high number of young speakers Irene Stefanini University of Turin Italy One of my favourite meetings with a real community feeling I ve started collaborations and made great friends here Rike Stelkens Population Genetics Stockholm University Sweden A great conference and academic environment networking opportunities are limitless Jose Antonio Urban Aragon International Laboratory for Human Genome Research National Autonomous University of Mexico LIIGH UNAM Mexico Speakers Orsolya Barabas University of Geneva Switzerland Pedro Beltrao ETH Zurich Switzerland Primrose Boynton Wheaton College Massachusetts USA Marjon de Vos University of Groningen The Netherlands Maitreya Dunham University of Washington USA Kevin Foster Unversity of Oxford UK Dan Jarosz Stanford University School of Medicine USA Paula Jouhten Aalto University Finland Kayla King remote speaker University of Oxford UK Kimberly Kline University of Geneva Switzerland kos T Kov cs DTU Bioengineering Denmark Gianni Liti Institute for Research on Cancer and Ageing of Nice IRCAN France Sara Mitri University of Lausanne Switzerland Carey Davis Nadell Dartmouth College USA Bal zs Papp Hungarian Academy of Sciences Hungary Alvaro San Millan Centro Nacional de Biotecnolog a CSIC Spain Anna Selmecki University of Minnesota Medical School USA Isheng Jason Tsai Academia Sinica Taiwan Kevin Verstrepen VIB KU Leuven Center for Microbiology Belgium Julia Vorholt ETH Zurich Switzerland Scientific organisers Kimberly Kline University of Geneva Switzerland Gianni Liti Institute for Research on Cancer and Ageing of Nice IRCAN France Sara Mitri University of Lausanne Switzerland Kiran Patil University of Cambridge UK Antonis Rokas Vanderbilt University USA Conference organiser Inna B sselmann Course and Conference Manager EMBL Heidelberg Germany Programme Got something to say Tweet it EMBOEvoEco Please note that due to the ongoing pandemic situation some speakers may need to join virtually to give their talk and the programme is subject to change Recorded talks will be accessible on demand for 2 weeks after the end of the event Please find the poster listing here Day 1 Wednesday 5 October 2022 Time Europe Berlin Speaker15 00 17 00Arrival and registration with light refreshments 17 00 19 00Session 1 Experimental EvolutionChair Gianni Liti Institute for Research on Cancer and Ageing of Nice IRCAN France17 00 17 15Opening remarks17 15 17 45Moving yeast experimental evolution research out of the lab and into the classroomMaitreya Dunham University of Washington USA17 45 18 15Genomic diversity across Candida auris clinical isolates shapes rapid development of antifungal resistance in vitro and in vivoAnna Selmecki University of Minnesota Medical School USA18 15 18 35Phage and Robotics Assisted Near Continuous EvolutionEmma Chory Massachusetts Institute of Technology USA18 35 18 55Bacterial evolved resistance against chemotherapies impairs drug efficacy in the worm hostAmir Mitchell University of Massachusetts Medical School USA19 00 20 30Dinner20 30 21 30Social event Science Pub Quiz Day 2 Thursday 6 October 2022 Time Europe Berlin Speaker 09 00 10 20Session 1 cont Experimental evolutionChair Gianni Liti Institute for Research on Cancer and Ageing of Nice IRCAN France 09 00 09 30Genes involved in protein folding and chromatin buffer genetic variationKevin Verstrepen VIB KU Leuven Center for Microbiology Belgium09 30 10 00Experimental evolution of Bacillus biofilms kos T Kov cs DTU Bioengineering Denmark10 00 10 20Exploring the limits of thermal tolerance in an Antarctic bacteriumMacarena Toll Riera ETH Z rich Switzerland10 20 10 50Coffee Break10 50 19 00Session 2 Genomic insights in Ecology EvolutionChair Antonis Rokas Vanderbilt University USA10 50 11 20Ecological genomics of pre domesticated Saccharomyces cerevisiae lineagesIsheng Jason Tsai Academia Sinica Taiwan11 20 11 50Unravelling the secrets of a model yeast in its home environmentPrimrose Boynton Wheaton College Massachusetts USA11 50 12 10A cohesive panel of 142 telomere to telomere genome assemblies unfolds the structural genetic diversity at the species scale in Saccharomyces cerevisiaeGilles Fischer CNRS Institut de Biologie Paris Seine Sorbonne Universit France12 10 12 30The natural diversity of the yeast proteome reveals chromosome wide dosage compensation in aneuploidsJulia Muenzner Charit Universit tsmedizin Berlin Germany12 30 14 00Lunch14 00 14 40Poster Introduction odd numbers 14 40 16 00 Poster Session 1 odd numbers 16 00 17 00Meet the Editors Maria Polychronidou Molecular Systems Biology GermanyRoland Roberts Public Library of Science UKMartina Rembold EMBO Reports GermanyNot available on demand 17 00 19 00Session 2 cont Genomic insights in Ecology EvolutionChair Antonis Rokas Vanderbilt University USA 17 00 17 30Within patient evolution of plasmid mediated antimicrobial resistanceAlvaro San Millan Centro Nacional de Biotecnolog a CSIC Spain17 30 18 00How genes jump DNA asymmetry drives transposition of antibiotic resistance in bacteriaOrsolya Barabas University of Geneva Switzerland18 00 18 20Evolutionary origins of orphan genes in prokaryotes of the human gutNikolaos Vakirlis BSRC Alexander Fleming GreeceNot available on demand18 20 18 40Assessing the contribution of gut to lung translocation to bacterial colonization and the dynamics of antibiotic resistance evolution in an ICU patientRachel Wheatley University of Oxford United KingdomRemote speaker18 40 19 00Mechanism of extensive genomic reshuffling and creation of diversity in the parasexual life cycle of a filamentous fungusMichael Knop University of Heidelberg ZMBH Germany19 00 20 30Dinner20 30 23 00After Dinner Drinks Day 3 Friday 7 October 2022 Time Europe Berlin Speaker 09 00 11 10Session 3 Systems and synthetic biologyChair Maitreya Dunham University of Washington USA09 00 09 30Genomic introgressions origin evolution and functionGianni Liti Institute for Research on Cancer and Ageing IRCAN France09 30 10 00Mechanisms of action of natural genetic variantsDan Jarosz Stanford University School of Medicine USA10 00 10 20Cell cell metabolite exchange creates a pro survival metabolic environment that extends lifespanClara Correia Melo Charit Medical University Berlin Francis Crick Institute London Germany UK10 20 10 50Coffee break10 50 11 10Reversion dynamics of copy number variants fitness costs versus benefits in the absence of selection pressureTitir De New York University USA 11 10 12 20Session 4 Assembly and Evolution of CommunitiesChair Orsolya Barabas University of Geneva Switzerland11 10 11 30Pathogenesis of polymicrobial biofilm associated infectionsKimberly Kline University of Geneva Switzerland11 30 11 45An efficient collective From individual proteome efficiency to collective community metabolismMatthias H lsmann ETH Zurich Eawag Switzerland11 45 12 00Influence of the adaptive immune system on the evolution of gut microbiotaCamille Ameline Instituto Gulbenkian de Ci ncia Portugal12 00 12 20Communities modulate clonal fitness in small populations of triple negative breast cancer cellsBenjamin Hershey IFOM the FIRC Institute of Molecular Oncology Italy12 20 14 00Lunch14 00 14 40Poster Introduction even numbers 14 40 16 00Poster Session 2 even numbers 16 00Free evening Day 4 Saturday 8 October 2022 Time Europe Berlin Speaker 09 00 12 20Session 4 cont Assembly and Evolution of CommunitiesChair Orsolya Barabas University of Geneva Switzerland09 00 09 30Competition and warfare in bacteriaKevin Foster University of Oxford UKNot available on demand09 30 09 50Mapping phage mediated gene flow in polymicrobial communities using laboratory evolutionYuval Mulla University of Cologne Germany09 50 10 10Understanding the effect of drugs on microbiome dynamics using ecological modelsNaomi van den Berg MRC Toxicology Unit University of Cambridge United Kingdom10 10 10 40Coffee break10 40 11 10Spatial ecology of predator prey dynamics in bacterial biofilmsCarey Nadell Dartmouth College USA11 10 11 40Ecological interactions drive the evolution of antibiotic resistanceMarjon de Vos University of Groningen The NetherlandsNot available on demand11 40 12 00Even allocation of benefits stabilizes microbial community engaged in metabolic division of laborMiaoxiao Wang ETH Zurich Switzerland12 00 12 20Gene loss promotes the emergence of metabolic cross feeding interactions in soil bacterial communitiesGhada Yousif Osnabr ck University Germany12 20 14 00Lunch 12 20 18 50Session 5 Understanding Predicting EvolutionChair Kiran Patil University of Cambridge UK14 00 14 30Gene loss and compensatory evolution promotes the emergence of morphological noveltiesBalazs Papp Hungarian Academy of Sciences Hungary14 30 15 00Predictive evolution of metabolic phenotypes using model designed selection environmentsPaula Jouhten Aalto University Finland15 00 15 20Distribution of fitness effects of cross species transformation reveals potential for fast adaptive evolutionMona F rster University of Cologne Germany15 20 15 50Coffee Break15 50 16 20Pathogen virulence evolution driven by host associated microbesKayla King University of Oxford UKRemote speaker16 20 16 50Mechanisms behind the context dependency of interspecies bacterial interactionsSara Mitri University of Lausanne Switzerland16 50 17 10Understanding the origin of lager yeastFrancisco Cubillos University of Santiago Chile17 10 17 40Coffee Break17 40 18 10Studying evolution through the lens of structural biology empowered by artificial intelligencePedro Beltrao ETH Zurich Switzerland18 10 18 30Metabolic efficiency reshapes the seminal relationship between pathogen growth rate and virulenceRichard Lindsay University of Exeter United Kingdom18 30 18 50Exploitation of an ancient dimerization interface enables allosteric regulation in cyanobacterial photoprotectionNiklas Steube Max Planck Institute for Terrestrial Microbiology Germany18 50 19 00Closing remarks19 00 21 00Dinner21 00 00 00Party with Live Music from Woodland Practical information Registration fees and abstract submission On site registration fees include admission conference materials COVID 19 safety measures meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Virtual registration fees include access to all of the talks livestreamed and on demand and facility to submit questions On site Academia 550On site PhD Student 450On site Industry 850Virtual Academia 175Virtual PhD Student 125Virtual Industry 225 NO visa support letters will be issued until payment of the registration fee is confirmed Accredited journalists may be eligible to register for complimentary press registration Registrants may be required to provide accreditation or equivalent proof of press membership after registration Please contact Inna B sselmann for more information Please note that we do not offer complimentary registrations for editors of scientific journals Confirmation and payment Registration will be on a first come first served basis Your place can only be confirmed after payment of the registration fee If you are added to our waiting list please consider taking advantage of our offerings to participate virtually On site participants Types of payments accepted are international bank transfers and credit card payments Virtual participants We are only able to accept card payments In exceptional cases we can accept bank transfers Please contact events embl de for details Abstract submission Only registered participants attending the on site event are eligible to submit an abstract Abstracts will not be accepted from virtual participants After you have logged in and successfully registered you will receive an email asking you to submit your abstract Click on the link provided and enter your abstract in the text box provided Alternatively you can submit your abstract by clicking on the link on the confirmation page directly after registering The same login credentials are used for both processes Please note Title The title should not exceed 20 words Only the first word of the title should start with a capital letter and the rest of the title should be in lowercase Authors and affiliations Please fill in the author s details as requested in the online form The compulsory details are First Name Last Name Organisation Name Affiliation or Company Country and Email Mark only one author as the role of First author and please don t forget to indicate who will be presenting The order of the authors will be listed as follows First Author Co First Author alphabetically if multiple co author s in the order added by the submitter Presentation types When submitting your abstract you can apply for an oral or poster presentation A selection process will take place with the results announced 2 3 weeks after the abstract submission deadline Please check our FAQs pages for further information on how to submit an abstract Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of both registration fee waivers and travel grants Availability is limited to participants attending on site events in Heidelberg and will be indicated during the abstract or motivation letter submission process Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course or conference Travel grant The travel grant will cover the cost of travel airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Course EMBL Conference or EMBO EMBL Symposium from within Europe up to 1000 for participants travelling to an EMBL Course EMBL Conference or EMBO EMBL Symposium from outside Europe up to 500 for any participant travelling to an EMBO Practical Course or EMBO Workshop up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Practical Course or EMBO Workshop Registration fees are only covered for EMBO Practical Courses or EMBO WorkshopsThe organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant EMBO practical courses and workshops only For EMBO Practical Course or EMBO Workshop participants with children there is the possibility to apply for a childcare grant to offset child care costs incurred by participants or speakers when participating at a course or conference Eligible costs include fees for a baby sitter or child care facility travel costs for a care giver or travel costs for taking the child to the meeting etc Please note that priority will be given to early stage researchers A maximum amount of 500 EUR can be awarded per participant applying for an EMBO Childcare Grant In order to apply for this grant for EMBO Workshops you must be registered by the abstract submission deadline Application You may apply for financial assistance when submitting your motivation letter for courses and abstract for conferences In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application For the Boehringer Ingelheim Fonds Travel Grant there is a pre application question during the motivation letter submission process and if selected you will be requested to complete a standard form and documentation consisting of your travel expense estimation Selection The scientific organisers will select the recipients of all financial assistance during the motivation letter or abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection is based on your current work or study location the reasons for needing financial support and the impact this event will have on your career Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details View our list of external funding opportunities and information on attending a conference as an event reporter For further information about financial assistance please refer to the FAQ page Accommodation and shuttles Accommodation is not included in the conference registration fee As further changes in our events are possible due to COVID 19 you should book flights trains and hotels with flexible options and favourable cancellation conditions The hotels below have rooms on hold for participants until 4 September 2022 in some cases at special rates Please quote the booking code EAE22 01 and confirm the exact price of the room with the hotel directly Hotel AnlageHotel ibis HeidelbergPremier Inn Heidelberg CityHotel Bayrischer Hof ISG Hotel Staycity Aparthotel HeidelbergB B HotelLeonardo Hotel Heidelberg City CentreSteffi s Hostel HeidelbergExzellenz Hotel Boarding HouseMeininger HeidelbergHotel Vier Jahreszeiten HeidelbergHotel Holl nder Hof Hotel Monpti Conference shuttle buses Conference shuttle buses are free of charge for participants and depart from designated bus stops near the hotels to EMBL and back mornings and evenings Download the bus schedule here The bus stops for this conference are Staycity Aparthotels Speyerer Str 7 Kurf rsten Anlage close to Main Train Station Premier Inn Kurf rsten Anlage 23 Leonardo Hotel City Centre Bergheimer Str 63 Neckarm nzplatzPeterskircheISG Hotel View Conference shuttle bus stops and hotels in a larger map Please note that not every bus stop will be used for every event Further details Address EMBL Meyerhofstra e 1 69117 Heidelberg Germany For further information on getting to EMBL Heidelberg visit Public Transportation to the Venue For information about accommodation and local transportation please refer to the FAQ page On site information Catering All meals and coffee breaks are included in the registration fee Our catering staff will prepare a wide variety of vegetarian meals meat and fish dishes soups pasta fresh fruit and vegetables as well as a variety of desserts Please wear your badge at all times when serving yourself No food or drinks are allowed in the auditorium Charging lockers There are lockers available next to the stairs leading down into the Auditorium You will find some of those equipped with sockets to charge your smartphone tablet etc Electricity and charging station In most places the electricity is 220 volts AC 50 cycles An adaptor and a plug that fits the German socket may be needed for your appliances laptop i e American Japanese etc A USB charging station for electronic devices is available at the registration desk EMBL merchandise EMBL Merchandise is available on Mon Thu 9 am 12 pm If you are interested in purchasing an EMBL souvenir products presented in the glass display in the registration area please ask at the registration desk for more information Health and safety notes Please read EMBL s COVID 19 safety policy for on site events Do not smoke in any EMBL building Eating and drinking is prohibited in the Auditorium and all laboratories Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required The first aid room is located next to the ATC Registration Desk room 10 205 Dial the Emergency number 222 from any EMBL internal phone only Where is the accident What happened How many injured Emergency number 06221 387 7821 from mobile phones Please report all accidents to the conference officer at the registration desk In case of fire Press the nearest fire alarm button or the Emergency number 222 from any internal phone A loud fire alarm will go off if an evacuation is required On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting pointsDo not use the lifts Beyond first aid Please remember to bring your own medication if needed to the conference Note that the next pharmacy is a 4 minute drive from the EMBL but for many medications you will be required to see a doctor to get a prescription Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg In any case the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary Internet Wi Fi is available everywhere on the premises no password required just log on to ATC Guest The eduroam network secure world wide roaming access service developed for the international research and education community is also available Lost and found Lost and Found are kept at the registration desk until the end of the conference Luggage There are lockers available on site to store your luggage which require a 2 EURO coin to operate There is another luggage room on level E0 which is free to use but remains unlocked during the conference Nursing room There is a nursing room available in the ATC Rooftop Lounge on level A29 Photography During the conference an EMBL Photographer may be taking photographs If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Printing We can help printing your boarding passes train ticket Please send it to events embl de and collect your print outs at the registration desk Room for prayer yoga and meditation There is a room for prayer mediation and yoga located on level E0 behind the Auditorium Please be respectful of other participants using the room Sightseeing 1 17 PM A variety of activities in Heidelberg can be found on the website of Heidelberg Marketing Travel to and from the venue During the event we provide conference shuttle buses to and from EMBL In addition there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time Information on the conference shuttle buses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page Useful German expressions EnglishGermanHelloHalloGoodbyeAuf WiedersehenGood morningGuten MorgenGood afternoonGuten TagGood eveningGuten AbendGood nightGute NachtI m sorryTut mir leidExcuse me Entschuldigen SieHow are you Wie geht s I m fine thanks And you Mir geht es gut danke und dir Ihnen What is your nameWie heisst du Wie heissen Sie My name isIch heisseDo you speak EnglishSprechen Sie Englisch I don t understandIch verstehe nichtPlease speak more slowlyK nnen Sie bitte langsamer sprechenThank youDanke sch nWhere is the toilet Wo ist die Toilette Please call me a taxiBitte rufen Sie mir ein TaxiHow do I get to Wie komme ich zum zur A beer two beers pleaseEin Bier zwei Bier bitteA glass of red white wine pleaseEin Glas Rot Weisswein bitteThe menu pleaseDie Speisekarte bitteIs there a local speciality Gibt es eine Spezialit t aus dieser Gegend I m VegetarianIch bin VegetarierIt was deliciousEs war hervorragendThe bill pleaseDie Rechnung bitteI have a headacheIch habe KopfschmerzenI have a sore throatIch habe HalsschmerzenMy stomach hurtsIch habe MagenschmerzenI m allergic toIch bin allergisch gegenI need a doctor who speaks EnglishGibt es einen Arzt der Englisch spricht Virtual participation Abstracts will not be accepted from virtual participants Only registered participants attending the on site event are eligible to submit an abstract What s included Access to all the livestreamed talksVideo library of the recorded talks during and after the eventFacility to submit questions Please note that only on site participants are able to submit abstracts and participate in the poster sessions Event platform We are using an event platform for this conference More information about the platform will be shared ahead of the conference Guidelines Do not broadcast the conference to unregistered participants You are encouraged to tweet and post about the event Tweet unless the speaker specifically says otherwise but be mindful of unpublished data Please do not capture transmit or redistribute data presented at the meeting Additional information can be found in our Code of Conduct Health and well being It is important to stay healthy and move around especially when you are attending an event virtually We have put together a few coffee break stretches and yoga videos in the conference platform for you to enjoy during the event How to ask questions Please use the Q A function in the event platform If you have any other questions you can go to the Help Desk in the event platform Click on more on the top menu and click Help Desk Time zone The programme is planned based on the Europe Berlin time zone unless otherwise stated Please take your time zone into consideration when planning your attendance Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page COVID 19 related questions COVID 19 information for on site events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Media partners EMBO Journal an EMBO Press journal International Union of Biochemistry and Molecular Biology Open Biology a Royal Society journal Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage...

Gianni Liti, Sara Mitri, Kiran Patil, Kimberley Kline, Antonis Rokas

EMBO Workshop

EMBL Heidelberg, Virtual

3 October - 7 October 2022

Single-cell RNA-seq analysis using R

Edit

Edit

September 12, 2022 00:002022CourseVirtual

Description This course will provide participants with an introduction and hands on training on modelling approaches tools and resources used in systems biology as well as touch on network analysis Computer models are increasingly used to understand the essential processes of biology Researchers in academic institutions as well as the pharmaceutical industry use mathematical models to generate hypotheses on how complex biomolecular systems work Modelling of biochemical pathways deregulated in disease conditions can offer mechanistic insights into the pathology help to elucidate mechanisms behind drug action and predict the dose required for treatment thus facilitating fundamental research and drug discovery This course will provide a helpful brief introduction to key modelling concepts and hands on training to use popular tools and resources used in this scientific field Virtual course This course has now been moved to a virtual format We will be using Zoom to run the live sessions all fully password protected with automated English closed captioning and transcription with support and both scientific and social networking opportunities provided by Slack and other methods taking different time zones into account In order to make the most out of the course you should make sure to have a stable internet connection throughout the week and are available between 09 00 17 30 British Summer Time BST each day In the week before the course there will be a brief induction session Computational practicals will run on EMBL EBI s virtual training infrastructure meaning participants will not require access to a powerful computer or install complex software on their own machines...

Juanita Riveros

Virtual

11 September - 12 September 2022

Edit

September 05, 2022 00:002022CourseEMBL Hamburg

Description If you are not automatically redirected please click here to visit the event website...

EMBO Practical Course

EMBL Hamburg

4 September - 13 September 2022

Current methods in cell biology

Edit

September 04, 2022 00:002022CourseEMBL Heidelberg

Description OverviewSpeakersProgrammePractical informationSponsors Overview Proof of COVID 19 vaccination or recovery is required to attend this on site course Please see EMBL s COVID 19 safety policy for on site events Course overview Experience modern cell biology at work not only see but also try out in practice how cutting edge technologies can be used to answer questions at the frontiers of cell biology It is a tradition that the entire faculty of the Cell Biology and Biophysics Unit of EMBL teaches the course to cover a broad spectrum of techniques The course also provides an excellent opportunity for participants and course faculty to discuss current and future challenges in cell biology Audience The course will be primarily aimed at postdocs and advanced graduate students who have developed an interest in cell biology We wish to attract cell biologists who want to acquire quantitative biophysical and computational methods as well as scientists including early career principle investigators with different backgrounds including physics chemistry engineering informatics etc who want to use their expertise to address current problems in cell biology We aim to balance the number of participants with a background in biology and participants coming from other disciplines A key criteria for selection is the potential benefit of adding novel cell biological methods to the students own research plans Preference will be given to students where there is little or no possibility that the student can acquire these technologies at her his home institution Modules Biological sample preparationMicroscopyImage analysisFluorescent probes developmentMechanobiology Learning outcomes The course will provide an update on the latest developments from the beginning to the end of an experiment This includes recent advances in fluorescent probe development e g FRET based activity probes through new techniques and tricks of biological sample preparation e g mounting of live organisms novel approaches in molecular biology cutting edge microscopy e g live imaging super resolution light microscopy and correlative light and electron microscopy and mechanobiology covering the complete range of biological complexity from single molecules to whole organisms Participants will learn how to analyze imaging data using Cellprofiler and Ilastik As the topics of the practicals are closely related to the current research in EMBL laboratories they will cover many experimental model organisms yeast mammalian cells fly ascidian and a wide variety of methods fluorescence and electron microscopy molecular biology in silico approaches image analysis This course is kindly supported by the Cell Biology and Biophysics Unit of EMBL Speakers Speakers trainers and staff Niccol Banterle EMBL Heidelberg Germany Sara Cuylen H ring EMBL Heidelberg Germany Claire Deo EMBL Heidelberg Germany Gautam Dey EMBL Heidelberg Germany Alba Diz Mu oz EMBL Heidelberg Germany Christer Ejsing EMBL Heidelberg Germany Jan Ellenberg EMBL Heidelberg Germany Kai Johnsson Max Planck Institute for Medical Research Germany Simone K hler EMBL Heidelberg Germany Anna Kreshuk EMBL Heidelberg Germany Peter Lenart Max Planck Institute for Multidisciplinary Sciences G ttingen Germany Julia Mahamid EMBL Heidelberg Germany Andrea Pauli Research Institute of Molecular Pathology Austria Rainer Pepperkok EMBL Heidelberg Germany Robert Prevedel EMBL Heidelberg Germany An ela ari Institute of Science and Technology Austria Yannick Schwab EMBL Heidelberg Germany Aubrey Weigel Janelia Research Campus USA Timo Zimmermann EMBL Heidelberg Germany Trainers LabPeopleBanterle DeyJohanna Melisa EMBL Heidelberg GermanyTocci Hiral Shah EMBL Heidelberg GermanyFelix Mikus EMBL Heidelberg GermanyDiz Mu oz Filipe Nunes Vicente EMBL Heidelberg GermanyJia Hui Lui EMBL Heidelberg GermanyRichard Bailleul EMBL Heidelberg GermanyAnusha Gopalan EMBL Heidelberg GermanyLinda Decker EMBL Heidelberg GermanyEllenbergKai Sandvold Beckwith EMBL Heidelberg GermanyAndreas Brunner EMBL Heidelberg GermanyK hlerCristina Pi eiro Lopez EMBL Heidelberg GermanyAna Rita Rodrigues Neves EMBL Heidelberg GermanyIvana avka EMBL Heidelberg GermanyPrevedelIvo Leite EMBL Heidelberg GermanySebastian Hambura EMBL Heidelberg GermanyLing Wang EMBL Heidelberg GermanyPepperkokMuzamil Majid Khan EMBL Heidelberg GermanyAliaksandr Halavatyi EMBL Heidelberg GermanyGiriram Mohana EMBL Heidelberg GermanyRiesAline Tschanz EMBL Heidelberg GermanyYu Le Wu EMBL Heidelberg GermanyLucas M ller EMBL Heidelberg GermanyTakahiro Deguchi EMBL Heidelberg GermanySoheil Mojiri EMBL Heidelberg GermanyMichal Skruzny EMBL Heidelberg GermanyPhilipp Hoess EMBL Heidelberg GermanySchwabNedal Djamil Darif EMBL Heidelberg GermanyMarianne Sandvold Beckwith EMBL Heidelberg GermanyIn s Romero Brey EMBL Heidelberg GermanyZimmermannTimo Zimmermann EMBL Heidelberg GermanyCuylenYuki Hayashi EMBL Heidelberg GermanyTerra Kuhn EMBL Heidelberg GermanyKreshukDominik Kutra EMBL Heidelberg GermanyFynn Beuttenm ller EMBL Heidelberg GermanyBAND PlatformYi Sun EMBL Bioimage ANalysis Desktop BAND PlatformJean Karim EMBL Bioimage ANalysis Desktop BAND Platform Scientific organisers Sara Cuylen H ring EMBL Heidelberg Germany Simone K hler EMBL Heidelberg Germany Course organisers Raili Pall Course and Conference Officer EMBL Heidelberg Germany Irena Provaznikova Training Lab Technician EMBL Heidelberg Germany Yvonne Yeboah Training Lab Manager EMBL Heidelberg Germany Programme Got something to say Tweet it with EMBOCellBiology Some speakers may need to join virtually to give their lecture or Q A and the programme is subject to change All times in the programme below are shown as the time in Europe Berlin Day 1 Sunday 4 September 2022 TimeSpeakerLocation16 45 17 00 RegistrationISG Hotel17 00 17 30Welcome and course overviewSimone Koehler EMBL Heidelberg GermanySara Cuylen Haering EMBL Heidelberg GermanyISG Hotel17 30 18 45Introduction by participants flash talks ISG Hotel19 00Buffet dinner ISG Hotel Day 2 Monday 5 September 2022 TimeSpeakerLocation08 40Bus from ISG Hotel to EMBL Main entranceISG Bus stop08 50 09 15Check inRoom 2029 15 10 00Lecture Light microscopy Basic principles and conceptsRobert Prevedel EMBL Heidelberg GermanyRoom 20210 00 10 30Coffee breakRoom 20210 30 11 15Lecture Superresolution MicroscopyTimo Zimmermann EMBL Heidelberg GermanyRoom 20211 30 14 00Poster session 1 ODD numbers with LunchOperon Foyer14 00 14 15Introduction to practicalsRoom 20214 15 18 00Practical 1Room 20218 00 18 45Lecture Super resolution applied the centriole caseNiccolo Banterle EMBL Heidelberg GermanyRoom 20219 00 19 15Bus from EMBL Main entrance to ISG HotelEMBL Bus stop19 15BBQ DinnerISG Hotel Day 3 Tuesday 6 September 2022 TimeSpeakerLocation08 40Bus from ISG Hotel to EMBL Main entranceISG Bus stop08 50 09 00Check inRoom 20209 00 09 45Lecture Single cell biology at large scale to study membrane traffic and organelle biogenesisRainer Pepperkok EMBL Heidelberg GermanyRoom 20209 45 11 45Poster session 2 EVEN numbers with coffee breakOperon Foyer11 45 12 45LunchEMBL Canteen12 45 18 00Practical 1Room 20218 00 18 45Lecture Integrative analysis of cell division across scalesJan Ellenberg EMBL Heidelberg GermanyRoom 20218 45 19 45Dinner EMBL Canteen20 00Bus from EMBL Main entrance to ISG HotelEMBL Bus stop Day 4 Wednesday 7 September 2022 TimeSpeakerLocation08 40Bus from ISG Hotel to EMBL Main entranceISG Bus stop08 50 09 00Check inRoom 20209 00 09 45Lecture Measuring Cell MechanicsAlba Diz Mu oz EMBL Heidelberg GermanyRoom 20209 45 10 00Coffee breakRoom 20210 00 11 00Seminar Computer simulations for cell reshapingAndela ari University College London UKSmall Operon11 00 11 45Meet the Speaker Andela ari Room 20211 45 12 45LunchEMBL Canteen12 45 13 00Group PhotoOutside IC12 45 18 00Practical 2Room 20218 15 19 45Pizza dinnerOperon Foyer19 45Bus from EMBL Main entrance to ISG HotelEMBL Bus stop Day 5 Thursday 8 September 2022 TimeSpeakerLocation08 40Bus from ISG Hotel to EMBL Main entranceISG Bus stop08 50 09 00Check inRoom 20209 00 09 45Lecture Electron microscopy for Cell Biology from CLEM to volume SEMYannick Schwab EMBL Heidelberg GermanyRoom 20209 45 10 00Coffee breakRoom 20210 00 11 00Seminar Using phospho proteomics and imaging to reveal conserved mechanisms of oocyte meiosisPeter Lenart Max Planck Institute for Multidisciplinary Sciences G ttingenSmall Operon11 00 11 45Meet the Speaker Peter LenartRoom 20211 45 12 45LunchEMBL Canteen12 45 18 00Practical 2Room 20218 00 18 45Lecture Molecular Views into Cells by in situ Cryo Electron TomographyJulia Mahamid EMBL Heidelberg GermanyRoom 20218 45 19 45Dinner EMBL Canteen20 00Bus from EMBL Main entrance to ISG HotelEMBL Bus stop Day 6 Friday 9 September 2022 TimeSpeakerLocation08 40Bus from ISG Hotel to EMBL Main entranceISG Bus stop08 50 09 00Check inRoom 20209 00 09 45Lecture Small molecule fluorophores for microscopy Claire Deo EMBL Heidelberg GermanyRoom 20209 45 10 00Coffee breakRoom 20210 00 11 00Seminar Fluorescent Probes for Cell BiologyKai Johnsson Max Planck Institute for Medical Research GermanySmall Operon11 00 11 45Meet the Speaker Kai JohnssonRoom 20211 45 12 45LunchEMBL Canteen12 45 17 15Practical 3Room 20217 15 18 45Networking activity with dinnerATC outdoor tent18 45Bus from EMBL Main entrance to ISG HotelEMBL Bus stop Day 7 Saturday 10 September 2022 TimeSpeakerLocation09 30Bus from ISG Hotel to EMBL Main entranceISG Bus stop09 45 10 00Check inRoom 20210 00 10 45Lecture Visualizing MeiosisSimone Koehler EMBL Heidelberg GermanyRoom 20210 45 11 00Coffee breakRoom 20211 00 11 45Lecture Evolutionary Cell BiologyGautam Dey EMBL Heidelberg GermanyRoom 20211 45 12 00European Research Infrastructure landscape and Euro BioImagingAastha Mathur Euro Bioimaging Bio Hub GermanyRoom 202 12 00 12 45LunchEMBL Canteen12 45 13 15Tour of the Imaging CenterTimo Zimmermann EMBL HeidelbergIC13 15 18 00Practical 3Room 20218 00Bus to ISG HotelEMBL Bus stop19 00Bus from ISG Hotel to Neckarm nzplatzISG Bus stop19 30Dinner downtown Day 8 Sunday 11 September 2022 Free day Day 9 Monday 12 September 2022 TimeSpeakerLocation08 40Bus from ISG Hotel to EMBL Main entranceISG Bus stop08 50 09 00Check inRoom 20209 00 09 45Lecture Image AnalysisAnna Kreshuk EMBL Heidelberg GermanyRoom 20209 45 10 00Coffee breakRoom 20210 00 11 00Seminar Segmentation of cellular organelles Aubrey Weigel Janelia Research Campus USASmall Operon11 00 11 45Meet the Speaker Aubrey WeigeRoom 20211 45 12 45LunchEMBL Canteen12 45 18 00Image analysis practical 1 Cellprofiler or Ilastik Computer Training Lab Room 20218 00 18 45Lecture From Screening to Cellular Function Discovery of a Cellular SurfactantSara Cuylen Haering EMBL Heidelberg GermanyRoom 20218 45 19 45Tapas dinnerATC Foyer20 00Bus from EMBL Main entrance to ISG HotelEMBL Bus stop Day 10 Tuesday 13 September 2022 TimeSpeakerLocation08 40Bus from ISG Hotel to EMBL Main entranceISG Bus stop08 50 09 00Check inRoom 20209 00 09 45Lecture A DNA toolset for spatial biologySinem Saka EMBL Heidelberg GermanyRoom 20209 45 10 00Coffee breakRoom 20210 00 11 00Seminar Egg to embryo transition in zebrafishAndrea Pauli IMP Vienna AustriaSmall Operon11 00 11 45Meet the Speaker Andrea PauliRoom 20211 45 12 45LunchEMBL Canteen12 45 18 00Image Analysis Practical 2 Cellprofiler or Ilastik Computer Training Lab Room 20218 00 18 30Feedback SessionRoom 20218 30 19 30Dinner at EMBLEMBL Canteen19 45Bus from EMBL Main entrance to ISG HotelEMBL Bus stop Practical information Registration fees and motivation letter The course is limited to 20 participants For selection purposes please note that your application will not be considered without a letter of motivation Registration Registration fees include admission course materials COVID 19 safety measures meals and coffee breaks This EMBO course includes accommodation and transportation to and from the ISG Hotel to the venue Academia 425PhD Student 425Industry 1000 Confirmation and payment The registration fee should be paid only after acceptance to the course The results will be announced approximately 2 3 weeks after the application deadline Motivation letter submission After you have logged in and successfully registered you will receive an email asking you to submit your motivation letter Click on the link provided and enter your motivation letter in the text box provided Alternatively you can submit your motivation letter by clicking on the link on the confirmation page directly after registering Instructions Include your relevant skills experience and qualifications showing why you would be suitable for the course Explain why you would like to attend including what you can contribute and how you think you will benefit from the course Please note The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised For more detailed information follow the instructions provided in our video on how to submit a course motivation letter Further details For further information about registration and motivation letter submission please refer to the FAQ page Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of both registration fee waivers and travel grants Availability is limited to participants attending on site events in Heidelberg and will be indicated during the abstract or motivation letter submission process Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course or conference Travel grant The travel grant will cover the cost of travel airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Course EMBL Conference or EMBO EMBL Symposium from within Europe up to 1000 for participants travelling to an EMBL Course EMBL Conference or EMBO EMBL Symposium from outside Europe up to 500 for any participant travelling to an EMBO Practical Course or EMBO Workshop up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Practical Course or EMBO Workshop Registration fees are only covered for EMBO Practical Courses or EMBO WorkshopsThe organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant EMBO practical courses and workshops only For EMBO Practical Course or EMBO Workshop participants with children there is the possibility to apply for a childcare grant to offset child care costs incurred by participants or speakers when participating at a course or conference Eligible costs include fees for a baby sitter or child care facility travel costs for a care giver or travel costs for taking the child to the meeting etc Please note that priority will be given to early stage researchers A maximum amount of 500 EUR can be awarded per participant applying for an EMBO Childcare Grant In order to apply for this grant for EMBO Workshops you must be registered by the abstract submission deadline Boehringer Ingelheim Fonds travel grant Applies to selected courses only Availability will be indicated during the abstract or motivation letter submission process This grant covers costs related to your attendance to the course registration travel and accommodation costs The grant is restricted to PhD students and postdocs who conduct basic biomedical research Whether you are eligible to apply for a travel grant depends on when you received your university entrance qualification e g Abitur A Levels High School Diploma Final State Examination for PhD and MD students as well as graduates the university entrance qualification must not have been obtained more than 11 years ago at the time of the envisaged course for postdocs the university entrance qualification must not have been obtained more than 13 years ago at the time of the envisaged course Application You may apply for financial assistance when submitting your motivation letter for courses and abstract for conferences In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application For the Boehringer Ingelheim Fonds Travel Grant there is a pre application question during the motivation letter submission process and if selected you will be requested to complete a standard form and documentation consisting of your travel expense estimation Selection The scientific organisers will select the recipients of all financial assistance during the motivation letter or abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection is based on your current work or study location the reasons for needing financial support and the impact this event will have on your career Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details View our list of external funding opportunities and information on attending a conference as an event reporter For further information about financial assistance please refer to the FAQ page Accommodation and shuttles Accommodation has been pre booked for you at the ISG Hotel for the default dates of Sunday 4 to Wednesday 14 September 2022 10 nights Please note that the course registration fee includes coverage of accommodation costs in twin rooms including breakfasts for your stay at the ISG but that you will be required to pay an additional cost of 21 EUR per night for a single room This should be paid by you directly to the ISG during your stay Any additional nights need to be booked and paid for by you We recommend that all course participants stay at the ISG Hotel which is the dedicated hotel for the course Local transport Shuttle buses will go from the ISG Hotel to EMBL and back mornings and evenings A bus schedule and location of the bus stops will be made available prior to the meeting Further details Address EMBL Heidelberg Meyerhofstra e 1 69117 Heidelberg GermanyFor further information on getting to EMBL Heidelberg visit our Travel Information page For enquiries about accommodation and local transportation please refer to the FAQ page Technical requirements and event software Technical requirements Below you will find the software and technical requirements for this course Participants need to bring their own laptops which will be used to remotely access EMBL virtual machines with pre installed software You will need admin rights to install the software required to access the virtual machines If you do not have admin rights please contact your technical support team in advance to make sure the software can be installed If you have a non standard HDMI port other than type A you need to bring an adaptor Keyboard and PC mouse are available for use with a standard USB port If you have a different port type such as USB C you will need to bring your own Event software The EMBL eCampus learning platform will be used to collaborate communicate and network with all of the course participants All participants will receive information on how to join shortly before the course We recommend using Chrome Safari or Mozilla Firefox browsers for eCampus Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page COVID 19 related questions COVID 19 information for on site events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage...

Sara Cuylen-Häring, Simone Köhler

EMBO Practical Course

EMBL Heidelberg

27 August - 30 August 2022

Transcription and chromatin

Edit

August 27, 2022 00:002022ConferenceEMBL Heidelberg, Virtual

Description OverviewSpeakersProgrammePractical informationSponsors Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Proof of COVID 19 vaccination or recovery is required for on site attendance Please see EMBL s COVID 19 terms and conditions Conference overview The EMBL Transcription and Chromatin meeting has a long standing tradition in shaping the field of transcriptional regulation The meeting brings together leading experts covering all aspects of transcription including cis regulatory function long range regulation 3 dimensional looping the basal transcriptional machinery RNA polymerase regulation and function nucleosome positioning chromatin modifications chromatin remodelling and epigenetic inheritance of transcriptional silencing The meeting contains many talks selected from the abstracts that are interspersed with invited speakers discussing the latest breakthroughs in transcriptional regulation The conference is designed to promote interactive discussions at both the talks and poster sessions Given the excellent line up of speakers and the meeting s outstanding reputation this is a must attend for anyone interested in cutting edge research in transcription Topics The conference will include the following topics Activators enhancer function evolution and modellingLong range transcriptional regulation and enhancersGeneral basal transcriptional machineryPol II function pausing and the role of RNA in transcriptionChromatin modifications and transcriptionTranscription regulation during embryonic development and stem cell reprogrammingGenome topology and three dimensional regulationSingle cell quantification What past participants say about this conference I had a great time at EMBL Transcription and Chromatin I enjoyed the variety of topics covered in the talks and I got a lot of input during the poster session I hope one day I can also give a talk at this conference Laura Breimann Max Delbr ck Center for Molecular Medicine Germany This was certainly the most exciting meeting I have ever attended The EMBL respires science of excellence I will be back Marcelo Fantappie Rio de Janeiro Federal University Brazil The EMBL Transcription and Chromatin Conference 2018 was excellent It provided me with an invaluable opportunity to network discuss my research with experts and learn a lot about the cutting edge research in the field I feel very lucky to have had the opportunity to attend this conference Katrina Mitchell Peter MacCallum Cancer Centre Australia Speakers Genevi ve Almouzni Institut Curie CNRS France Karim Jean Armache New York University USA Karen Arndt University of Pittsburgh USA David Bentley University of Colorado USA Wendy Bickmore The University of Edinburgh UK Adrian Bracken Trinity College Dublin Ireland Sarah Bray University of Cambridge UK Ibrahim Ciss Max Planck Institute of Immunobiology and Epigenetics Germany Patrick Cramer Max Planck Institute for Multidisciplinary Sciences Germany Xavier Darzacq University of California Berkeley USA Sevin Ercan New York University USA Emma Farley University of California San Diego USA Melissa Harrison University of Wisconsin Madison USA Kristian Helin The Institute of Cancer Research UK Karl Peter Hopfner Ludwig Maximilians University of Munich Germany Mike Levine Princeton University USA Susanne Mandrup University of Southern Denmark Denmark Eva Nogales University of California Berkeley and Howard Hughes Medical Institute USA Antoine Peters Friedrich Miescher Institute for Biomedical Research Switzerland Robert Schneider Helmholtz Zentrum M nchen Germany Dirk Sch beler Friedrich Miescher Institute for Biomedical Research Switzerland Alexander Stark Research Institute of Molecular Pathology IMP Austria Dylan Taatjes University of Colorado Boulder USA Kiku Tachibana Max Planck Institute of Biochemistry Germany Maria Elena Torres Padilla Helmholtz Zentrum M nchen Germany Scientific organisers Karen Adelman Harvard Medical School USA Eileen Furlong EMBL Heidelberg Germany J rg M ller Max Planck Institute of Biochemistry Germany Peter Verrijzer Erasmus University Medical Center The Netherlands Conference officer Nathalie Sneider EMBL Heidelberg Germany Programme Got something to say Tweet it EMBLTranscript Please note that due to the ongoing pandemic situation some speakers may need to join virtually to give their talk and the programme is subject to change Recorded talks will be accessible on demand for 2 weeks after the end of the event All times in the programme below are shown as the time in Europe Berlin Please find the poster listing here Day 1 Saturday 27 August 2022 TimeSpeaker14 30 17 00Arrival and registration15 30 16 20Pre conference workshop with LUMICKS17 00 17 15Opening remarks by scientific organisers17 15 19 45Session 1Session chairs Eileen Furlong J rg M ller17 15 17 35Mechanisms of chromatin transcriptionPatrick Cramer Max Planck Institute for Multidisciplinary Sciences GermanyAVAILABLE ON DEMAND AFTER LIVE STREAM 17 35 17 55Enhancer function in the 3D genome is close enough enough Wendy Bickmore The University of Edinburgh United KingdomAVAILABLE ON DEMAND AFTER LIVE STREAM 17 55 18 10Gene repression dynamics are modulated by transiently active regulatory elementsMarit Vermunt The Children s Hospital of Philadelphia United States of AmericaLIVE STREAM ONLY18 10 18 25Cryo EM structure of the human Sirtuin 6 nucleosome complexJean Paul Armache Penn State University United States of AmericaLIVE STREAM ONLY18 25 18 45The pausing zone the torpedo and control of RNA polymerase II elongation and terminationDavid Bentley University of Colorado School of Medicine United States of AmericaAVAILABLE ON DEMAND AFTER LIVE STREAM 18 45 19 05Histone Variants and Chaperones in shaping chromatin and cell fateGenevi ve Almouzni Institut Curie CNRS France AVAILABLE ON DEMAND AFTER LIVE STREAM 19 05 21 00Dinner in the Canteen21 00 23 00After dinner drinks Day 2 Sunday 28 August 2022 Time Speaker 09 00 12 30Session 2Session chairs Maria Elena Torres Padilia David Bentley09 00 09 20Super resolution imaging of transcription in living cellsIbrahim Ciss Max Planck Institute for Immunobiology Epigenetics Germany LIVE STREAM ONLY09 20 09 35The pioneer transcription factor SOX2 is constantly required to maintain open chromatin and control pluripotent gene expressionElzo de Wit Oncode Institute Netherlands Cancer Institute The Netherlands AVAILABLE ON DEMAND AFTER LIVE STREAM 09 35 09 50Dosage matters regulation dynamics and consequences of histone H2A ubiquitylationPeter Verrijzer Erasmus University Medical Center The Netherlands AVAILABLE ON DEMAND AFTER LIVE STREAM 09 50 10 05Targeted protein degradation defines direct targets and mechanisms of control by PAX3 FOXO1Kristy Stengel Vanderbilt University United States of America AVAILABLE ON DEMAND AFTER LIVE STREAM 10 05 10 25Decoding the Notch signalSarah Bray University of Cambridge United KingdomLIVE STREAM ONLY10 25 11 05Coffee Break11 05 11 25Catalytic and non catalytic mechanisms of chromatin modifiersKarim Jean Armache New York University United States of America AVAILABLE ON DEMAND AFTER LIVE STREAM 11 25 11 40G quadruplexes are promoter elements controlling nucleosome exclusion and RNA polymerase II pausingJean Christophe Andrau Institut de G n tique Mol culaire de Montpellier IGMM France AVAILABLE ON DEMAND AFTER LIVE STREAM 11 40 11 55PR DUB preserves Polycomb repression by preventing excessive accumulation of H2Aub an antagonist of chromatin compactionJacques Bonnet Max Planck Institute of Biochemistry Germany AVAILABLE ON DEMAND AFTER LIVE STREAM 11 55 12 10The RNA binding surface of PRC2 is required for the histone methylation of chromatin in an RNA independent mannerChen Davidovich Monash University AustraliaLIVE STREAM ONLY12 10 12 30Molecular principles of PRC2 regulationEva Nogales University of California Berkeley United States of America AVAILABLE ON DEMAND AFTER LIVE STREAM 12 30 14 15Lunch14 15 16 45Poster Session 1 odd 16 45 19 00Session 3Session chairs Alex Stark and Susanne Mandrup16 45 17 05Affinity optimizing enhancer variants disrupt development and drive diseaseEmma Farley University of California San Diego United States of AmericaAVAILABLE ON DEMAND AFTER LIVE STREAM 17 05 17 25How genomes encode timeMichael Levine Princeton University United States of AmericaAVAILABLE ON DEMAND AFTER LIVE STREAM 17 25 17 40Regulating gene expression in 3D during embryonic developmentYad Ghavi Helm Institute of Functional Genomics of Lyon IGFL France AVAILABLE ON DEMAND AFTER LIVE STREAM This talk is now virtual 17 40 17 55The logic of native enhancer promoter compatibility and cell type specific gene expression tuningChunaram Choudhary University of Copenhagen Denmark AVAILABLE ON DEMAND AFTER LIVE STREAM 17 55 18 10Short break18 10 18 25Control of enhancer activity by DNA methylationArnaud Krebs EMBL Heidelberg Germany AVAILABLE ON DEMAND AFTER LIVE STREAM 18 25 18 40The double edged sword of transcription factor clusteringTineke Lenstra Netherlands Cancer Institute Oncode Institute The NetherlandsLIVE STREAM ONLY18 40 19 00Live cells single molecule biochemistry what can we learn by interrogating molecular interactions in their cellular context Xavier Darzacq University of California Berkeley United States of America AVAILABLE ON DEMAND AFTER LIVE STREAM 19 00 21 00Dinner21 00 23 00After dinner drinks Day 3 Monday 29 August 2022 TimeSpeaker09 00 12 30Session 4Session chairs Karim Jean Armache Genevieve Almouzni09 00 09 20Structural mechanism of extranucleosomal DNA readout by the INO80 complexKarl Peter Hopfner Ludwig Maximilians University of Munich Germany AVAILABLE ON DEMAND AFTER LIVE STREAM 09 20 09 35Dynamic positioning of H2A Z throughout the cell cycle safeguards the pluripotent gene expression programArmelle Tollenaere EPFL Switzerland AVAILABLE ON DEMAND AFTER LIVE STREAM 09 35 09 50Integrator endonuclease drives promoter proximal termination at all RNA polymerase II transcribed lociChad Stein Harvard Medical School United States of America AVAILABLE ON DEMAND AFTER LIVE STREAM 09 50 10 05An evolutionary advanced mechanism of gene expression control the regulation of SWI SNF by the histone variant H2A BDavid Tremethick The Australian National University The John Curtin School of Medical Research AustraliaLIVE STREAM ONLY10 05 10 25Probing the direct effects of the Paf1 complex on transcription and histone modificationsKaren Arndt University of Pittsburgh United States of AmericaAVAILABLE ON DEMAND AFTER LIVE STREAM 10 25 11 05Coffee Break11 05 11 25Mechanistic studies of TFIIH kinase CDK7 reveal regulatory roles at all transcriptional stages and coordination with other kinasesDylan Taatjes University of Colorado Boulder United States of AmericaAVAILABLE ON DEMAND AFTER LIVE STREAM 11 25 11 40TAF1 dependent co translational assembly of the basal transcription factor holo TFIIDLaszlo Tora Institut de G n tique et de Biologie Mol culaire et Cellulaire IGBMC FranceLIVE STREAM ONLY11 40 11 55Structural basis of nucleosome retention during transcription elongationLucas Farnung Harvard Medical School United States of AmericaAVAILABLE ON DEMAND AFTER LIVE STREAM 11 55 12 10Structural basis of TFIIIC dependent RNA Polymerase III transcription initiationAnna Talyzina Northwestern University United States of AmericaLIVE STREAM ONLY 12 10 12 30Finding your place Transcription factors as sensors and modifiers of chromatinDirk Sch beler Friedrich Miescher Institute for Biomedical Research SwitzerlandAVAILABLE ON DEMAND AFTER LIVE STREAM 12 30 14 15Lunch14 15 16 45Poster Session 2 even 16 45 19 00Session 5Chaired by Emma Farley Kristian Helin16 45 17 05Enhancer networks controlling adipocyte lineage determinationSusanne Mandrup University of Southern Denmark DenmarkLIVE STREAM ONLY17 05 17 25Novel players in chromatinRobert Schneider Helmholtz Zentrum M nchen GermanyLIVE STREAM ONLY17 25 17 40Cell type differential targeting of SETDB1 prevents aberrant CTCF binding chromatin looping and cis regulatory interactionsLut Fei Tam Hong Kong University of Science and Technology Hong KongAVAILABLE ON DEMAND AFTER LIVE STREAM 17 40 17 55SOA confers X chromosome dosage compensation in Anopheles gambiae mosquitoesClaudia Keller Valsecchi Institute of Molecular Biology IMB GermanyLIVE STREAM ONLY17 55 18 10Short break18 10 18 25RNA polymerase II is essential for enhancer promoter contacts and antagonises CTCF loopingArgyris Papantonis University Medical Center Goettingen GermanyAVAILABLE ON DEMAND AFTER LIVE STREAM 18 25 18 40The Mediator complex regulates enhancer promoter interactionsMarieke Oudelaar Max Planck Institute for Multidisciplinary Sciences GermanyAVAILABLE ON DEMAND AFTER LIVE STREAM 18 45 19 00Acute perturbation strategies for interrogating the elongating RNA polymerase II and its role in malignanciesAli Shilatifard Northwestern University Feinberg School of Medicine United States of AmericaLIVE STREAM ONLY19 00 21 00Dinner21 00 23 00After dinner drinks Day 4 Tuesday 30 August 2022 TimeSpeaker09 00 12 50Session 6Chaired by Wendy Bickmore and Melissa Harrison09 00 09 20Regulation of condensin translocation by topoisomerases I and II in C elegansSevinc Ercan New York University United States of Americ AVAILABLE ON DEMAND AFTER LIVE STREAM This talk is now virtual 09 20 09 40Histone Demethylases KDM2A 2B safeguard the Oocyte Methylome and Embryonic DevelopmentAntoine Peters Friedrich Miescher Institute for Biomedical Research SwitzerlandLIVE STREAM ONLY09 40 09 55Targeted disruption of transcription bodies causes widespread activation of transcriptionNadine Vastenhouw University of Lausanne SwitzerlandLIVE STREAM ONLY09 55 10 10TADs can still establish during early embryogenesis in the absence of individual insulator proteins but cause locus specific effectsEileen Furlong EMBL Heidelberg GermanyAVAILABLE ON DEMAND AFTER LIVE STREAM 10 10 10 25Control of transcriptional identity by Polycomb group proteinsDiego Pasini European Institute of Oncology ItalyLIVE STREAM ONLY10 25 10 45Mechanisms of zygotic genome activation in mouse embryosKikue Tachibana Max Planck Institute of Biochemistry GermanyLIVE STREAM ONLY10 45 11 25Coffee Break11 25 11 45Heterochromatin formation and transcriptional regulation at the beginning of mammalian developomentMaria Elena Torres Padilla Helmholtz Zentrum M nchen GermanyLIVE STREAM ONLY11 45 12 00Alu repeats at the boundaries of regulatory elements shape the epigenetic environment of immune genes in T cellsChristian Muchardt Sorbonne Universit FranceLIVE STREAM ONLY12 00 12 15Polycomb Repressive Complex 2 establishes H3K27me3 at developmental genes in oocytes and impacts offspring development Ruby OberinHudson Institute of Medical Research and Monash University Australia AVAILABLE ON DEMAND AFTER LIVE STREAM 12 15 12 30The chromatin landscape during early embryo development at single cell resolutionIsabel Guerreiro Hubrecht Institute The NetherlandsLIVE STREAM ONLY12 30 12 50H3K4me3 regulates RNA polymerase II promoter proximal pause releaseKristian Helin Memorial Sloan Kettering Cancer Center United States of AmericaLIVE STREAM ONLY12 50 14 30Lunch14 30 17 00Poster session 3 odd and even numbers 17 00 19 30Session 7Chaired by Karen Adelman Peter Verrijzer17 00 17 20Interplay between PRC2 subcomplexes and canonical PRC1 in development and diseaseAdrian P Bracken Trinity College Dublin Ireland AVAILABLE ON DEMAND AFTER LIVE STREAM 17 20 17 40Pioneering the developmental frontierMelissa Harrison University of Wisconsin Madison United States of AmericaLIVE STREAM ONLY 17 40 17 55An autoregulatory feedback loop converging on H2A ubiquitination drives synovial sarcomaAna Banito German Cancer Research Center DKFZ Hopp Children Cancer Center KiTZ GermanyAVAILABLE ON DEMAND AFTER LIVE STREAM 17 55 18 10Short break18 10 18 25Distinct promoter enhancer communication patterns during developmental gene activationAngelika Feldmann German Cancer Research Center DKFZ GermanyAVAILABLE ON DEMAND AFTER LIVE STREAM 18 25 18 40On microscope staging of live cells reveals changes in the dynamics of transcriptional bursting during differentiationEd Tunnacliffe University of Oxford United KingdomAVAILABLE ON DEMAND AFTER LIVE STREAM 18 40 19 00Decoding transcriptional regulation in DrosophilaAlexander Stark Research Institute of Molecular Pathology IMP AustriaLIVE STREAM ONLY19 00 19 15Closing remarks19 15 20 45Conference dinner20 45 22 15After dinner drinks live music outside Practical information Registration fees and abstract submission There is currently a waiting list in place for on site participation We do expect a few places to become available and for those who register for the waiting list we will aim to contact you by the end of June to let you know if you can attend On site registration fees include admission conference materials COVID 19 safety measures meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Virtual registration fees include access to all of the talks livestreamed and on demand and facility to submit questions On site Academia 775On site PhD Student 675On site Industry 975Virtual Academia 175Virtual PhD Student 125Virtual Industry 225 NO visa support letters will be issued until payment of the registration fee is confirmed Accredited journalists may be eligible to register for complimentary press registration Registrants may be required to provide accreditation or equivalent proof of press membership after registration Please contact Nathalie Sneider for more information Please note that we do not offer complimentary registrations for editors of scientific journals Confirmation and payment Registration will be on a first come first served basis Your place can only be confirmed after payment of the registration fee If you are added to our waiting list please consider taking advantage of our offerings to participate virtually On site participants Types of payments accepted are international bank transfers and credit card payments Virtual participants We are only able to accept card payments In exceptional cases we can accept bank transfers Please contact Nathalie Sneider for details Abstract submission Only registered participants attending the on site event are eligible to submit an abstract Abstracts will not be accepted from virtual participants After you have logged in and successfully registered you will receive an email asking you to submit your abstract Click on the link provided and enter your abstract in the text box provided Alternatively you can submit your abstract by clicking on the link on the confirmation page directly after registering The same login credentials are used for both processes Please note Title The title should not exceed 20 words Only the first word of the title should start with a capital letter and the rest of the title should be in lowercase Authors and affiliations Please fill in the author s details as requested in the online form The compulsory details are First Name Last Name Organisation Name Affiliation or Company Country and Email Mark only one author as the role of First author and please don t forget to indicate who will be presenting The order of the authors will be listed as follows First Author Co First Author alphabetically if multiple co author s in the order added by the submitter Presentation types When submitting your abstract you can apply for an oral or poster presentation A selection process will take place with the results announced 2 3 weeks after the abstract submission deadline Please check our FAQs pages for further information on how to submit an abstract Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of both registration fee waivers and travel grants Availability is limited to participants attending on site events in Heidelberg and will be indicated during the abstract or motivation letter submission process Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course or conference Travel grant The travel grant will cover the cost of travel airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Course EMBL Conference or EMBO EMBL Symposium from within Europe up to 1000 for participants travelling to an EMBL Course EMBL Conference or EMBO EMBL Symposium from outside Europe up to 500 for any participant travelling to an EMBO Practical Course or EMBO Workshop up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Practical Course or EMBO Workshop Registration fees are only covered for EMBO Practical Courses or EMBO WorkshopsThe organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Application You may apply for financial assistance when submitting your motivation letter for courses and abstract for conferences In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Selection The scientific organisers will select the recipients of all financial assistance during the motivation letter or abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection is based on your current work or study location the reasons for needing financial support and the impact this event will have on your career Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details View our list of external funding opportunities and information on attending a conference as an event reporter For further information about financial assistance please refer to the FAQ page Accommodation and shuttles Accommodation is not included in the conference registration fee As further changes in our events are possible due to COVID 19 you should book flights trains and hotels with flexible options and favourable cancellation conditions The hotels below have rooms on hold for participants until Tuesday 26 July 2022 in some cases at special rates Please quote the booking code TRM22 01 and confirm the exact price of the room with the hotel directly Hotel Anlage Hotel Holl nder Hof Staycity Aparthotel Heidelberg Hotel Bayrischer Hof Hotel ibis Heidelberg Steffi s Hostel Heidelberg B B Hotel Leonardo Hotel Heidelberg City Centre Hotel Vier Jahreszeiten Heidelberg Exzellenz Hotel Boarding HousePremier Inn Heidelberg City Conference shuttle buses Conference shuttle buses are free of charge for participants and depart from designated bus stops near the hotels to EMBL and back mornings and evenings Download the bus schedule here The bus stops for this conference are Staycity Aparthotel close to B B Hotel and Main Train Station Kurf rsten Anlage opposite Main Train Station Premier Inn Hotel Kurf rsten Anlage 23Leonardo Hotel City Centre Bergheimer Strasse Neckarm nzplatzPeterskirche View Conference shuttle bus stops and hotels in a larger map Please note that not every bus stop will be used for every event Further details Address EMBL Meyerhofstra e 1 69117 Heidelberg Germany For further information on getting to EMBL Heidelberg visit Public Transportation to the Venue For information about accommodation and local transportation please refer to the FAQ page Virtual participation What s included Access to all the livestreamed talksVideo library of the recorded talks during and after the eventFacility to submit questions Please note that only on site participants are able to submit abstracts and participate in the poster sessions Event platform We are using an event platform for this conference More information about the platform will be shared ahead of the conference Guidelines Do not broadcast the conference to unregistered participants You are encouraged to tweet and post about the event Tweet unless the speaker specifically says otherwise but be mindful of unpublished data Please do not capture transmit or redistribute data presented at the meeting Additional information can be found in our Code of Conduct Health and well being It is important to stay healthy and move around especially when you are attending an event virtually We have put together a few coffee break stretches and yoga videos in the conference platform for you to enjoy during the event How to ask questions Please use the Q A function in the event platform If you have any other questions you can go to the Help Desk in the event platform Click on more on the top menu and click Help Desk Time zone The programme is planned based on the Europe Berlin time zone unless otherwise stated Please take your time zone into consideration when planning your attendance Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page COVID 19 related questions COVID 19 information for on site events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Bronze sponsors Event sponsor Genome Research a Cold Spring Harbor Laboratory Press journal Media partners EMBO Journal an EMBO Press journal Genes and Development a Cold Spring Harbor Laboratory Press journal International Union of Biochemistry and Molecular Biology Open Biology a Royal Society journal Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage...

Karen Adelman, Eileen Furlong, Jürg Müller, Peter Verrijzer

EMBL Conference

EMBL Heidelberg, Virtual

21 August - 29 August 2022

Advances in cryo-electron microscopy and 3D image processing

Edit

August 21, 2022 00:002022CourseEMBL Heidelberg

Description OverviewSpeakersProgrammePractical informationSponsors Overview Proof of COVID 19 vaccination or recovery is required to attend this on site course Please see EMBL s COVID 19 safety policy for on site events Course overview Cryo electron microscopy cryoEM has become the method of choice for determining atomic level structures of large and flexible macromolecular assemblies that are notoriously difficult to study by other techniques In addition it has unique capabilities for obtaining structural information in situ within complex cellular environments and to deal with biologically heterogeneous samples With the advent of the cryoEM resolution revolution the method has undergone a tremendous growth in user base Yet the underlying methods are complex and under constant development Therefore in depth advanced training is essential to ensure future generations can adapt emerging technologies to expand into new areas of biological research This course provides the theoretical and practical foundations of advanced cryoEM techniques from sample preparation to data collection to image processing Audience To meet the exceptional demand of the field for advanced training this course is aimed at PhD students and Post Docs with experience in cryoEM and 3D image processing It will enable them to better apply cryoEM to their cutting edge research disseminate their gained expertise to colleagues at their home institution and eventually to develop cryoEM methods beyond the state of the art Modules resources During this course we will focus on the following aspects Single particle reconstruction cisTEM Relion cryoSPARC Subtomogram averagingAtomic models model building and integrative modeling Session at the microscopes cryo EM ET and cryo FIB Latest developments in instrumentations Learning outcomes After this course students should have learned advanced topics of cryo EM ET data collection and image processing and be able to apply and adapt these techniques for challenging research projects What past participants say about the course This a world class course The access to experts and cutting edge techniques is incredible Corbin Black McGill University Canada The EMBL Imaging Centre training activities are generously supported by the Boehringer Ingelheim Foundation Speakers Speakers trainers and staff Bridget Carragher New York Structural Biology Center USA Radostin Danev The University of Tokio Japan Frank DiMaio University of Washington USA Phillip Erdmann Human Technopole Italy Robert Glaeser Lawrence Berkeley National Laboratory USA virtual Timothy Grant University of Madison USA Nikolaus Grigorieff University of Massachusetts Medical School USA Hui Guo The Hospital for Sick Children Canada Wim Hagen EMBL Heidelberg Germany Richard Henderson MRC Laboratory of Molecular Biology UK Jean Karime Heriche EMBL Heidelberg Germany Thomas Hoffman EMBL Heidelberg Germany Sagar Khavnekar Max Planck Institute of Biochemistry Germany Dari Kimanius MRC Laboratory of Molecular Biology UK Jan Kosinski EMBL Hamburg Germany Wanda Kukulski University of Bern Switzerland Julia Mahamid EMBL Heidelberg Germany Kelly Nguyen MRC Laboratory of Molecular Biology UK Eva Nogales Howard Hughes Medical Institute and University of California Berkeley USA Lori Passmore MRC Laboratory of Molecular Biology UK Ardan Patwardhan EMBL EBI Hinxton UK virtual Alexis Rohou Genentech USA Chris Russo MRC Laboratory of Molecular Biology UK Sjors Scheres MRC Laboratory of Molecular Biology UK virtual Henning Stahlberg cole Polytechnique F d rale de Lausanne Switzerland Yi Sun EMBL Heidelberg Germany Beata Turonova Max Planc Institute of Biophysics Germany virtual William Wan Vanderbilt University USA Giulia Zanetti Birkbeck College UK Scientific organisers Sebastian Eustermann EMBL Heidelberg Germany Julia Mahamid EMBL Heidelberg Germany Simone Mattei EMBL Heidelberg Germany Lori Passmore MRC Laboratory of Molecular Biology UK Henning Stahlberg cole Polytechnique F d rale de Lausanne Switzerland Course organisers Iva Gavran Course and Conference Officer EMBL Heidelberg Germany Irena Provaznikova Training Lab Technician EMBL Heidelberg Germany Programme Got something to say Tweet it with EMBOCryoEM Some pre course work will be required and will be shared in advance of the course All times in the programme below are shown as the time in Europe Berlin Programme is preliminary and subject to change Day 1 Sunday 21 August 2022 TimeSpeakersLocation13 45 14 00 Shuttle to EMBLISG bus stop 14 00 15 00Registration and light refreshmentsATC registration15 00 15 15Introduction and housenote slides Julia Mahamid EMBL Heidelberg Germany Courtyard Room 15 15 15 30 Course overviewSimone Mattei EMBL Heidelberg GermanyCourtyard Room 15 30 16 30Cutting edge research with Single Particle AnalysisEva Nogales Howard Hughes Medical Institute and University of California Berkeley USACourtyard Room 16 30 17 00Coffee breakFlex Lab17 00 18 00Cutting edge research with TomographyGiulia Zanetti Birkbeck College UKCourtyard Room18 00 19 00An overview of the past and future of cryoEMRichard Henderson MRC Laboratory of Molecular Biology UKCourtyard Room 19 00 19 45Pizza dinnerRooftop lounge 19 45 21 45Student presentations IRooftop lounge22 00Shuttle to ISG Hotel Bus stop Day 2 Monday 22 August 2022 TimeSpeakersLocation08 35Shuttle to EMBL ISG08 50 09 00Overview of the dayCourtyard Room 09 00 10 00Cryo EM image formation and optics Chris Russo MRC Laboratory of Molecular Biology UKCourtyard Room 10 00 11 00Introduction to the microscopeRadostin Danev The University of Tokyo JapanCourtyard Room 11 00 12 00 Fundamentals of image processing and Maximum likelihood approachesNikolaus Grigorieff University of Massachusetts Medical School USACourtyard Room12 00 13 00Lunch breakCanteen13 00 14 00Specimen preparation vitrification and sample supportsLori Passmore MRC Laboratory of Molecular Biology UKCourtyard Room 14 00 15 00Handling heterogeneity in cryoEM sample preparationKelly Nguyen MRC Laboratory of Molecular Biology UKCourtyard Room 15 00 15 30Coffee breakFlex Lab 15 30 17 00Forces in vitrification beam damage and phase plates past and future of cryoEM II Robert Glaeser Lawrence Berkeley National Laboratory USA remote Courtyard Room 17 00 18 00Panel discussionDiscussion leader Lori Passmore MRC Laboratory of Molecular Biology UKCourtyard Room 18 00 19 00DinnerCanteen19 00 21 00Student presentations IIRooftop lounge21 15Shuttle to ISG HotelBus stop Day 3 Tuesday 23 August 2022 TimeSpeakersLocation08 35Shuttle to EMBL ISG bus stop 08 50 09 00Overview of the dayCourtyard Room 09 00 10 00AI for cryoEM image processingSjors Scheres MRC Laboratory of Molecular Biology UKCourtyard Room 10 00 11 00Handling heterogeneity in cryoEM image processingSjors Scheres MRC Laboratory of Molecular Biology UKCourtyard Room 11 00 12 00 Panel discussionDiscussion leader Sebastian Eustermann EMBL Heidelberg GermanyCourtyard Room12 00 13 00Lunch breakCanteen13 00 15 30PracticalSession 1 Single Particle Analysis RelionSession 2 Single Particle Analysis cisTEMSession 3 Single Particle Analysis cryoSPARCSession 4 Subtomo AnalysisIC 15 104IC 15 125IC 15 114Computer training lab15 30 16 00Coffee break Flex Lab 16 00 18 00PracticalSession 1 continued Single Particle Analysis RelionSession 2 continued Single Particle Analysis cisTEMSession 3 continued Single Particle Analysis cryoSPARCSession 4 continued Subtomo AnalysisIC 15 104IC 15 125IC 15 114Computer training lab 18 00 19 00Vegetarian dinnerCanteen19 00 21 00Student presentations IIIRooftop lounge21 15Shuttle to ISG HotelBus stop Day 4 Wednesday 24 August 2022 TimeSpeakersLocation08 35Shuttle to EMBL ISG bus stop 08 50 09 00Overview of the dayCourtyard Room 09 00 10 00Best practices of microscopy for data collection for Single Particle Analysis and Tomography Wim Hagen EMBL Heidelberg GermanyCourtyard Room 10 00 11 00Practical considerations of initial image processing on the fly processing Henning Stahlberg EPFL SwitzerlandCourtyard Room 11 00 12 00 Panel discussionDiscussion leader Simone Mattei EMBL Heidelberg Germany Courtyard Room12 00 13 00Lunch breakCanteen13 00 15 30PracticalSession 1 continued Single Particle Analysis RelionSession 2 continued Single Particle Analysis cisTEMSession 3 continued Single Particle Analysis cryoSPARCSession 4 continued Subtomo AnalysisIC 15 125IC 15 114IC 15 104Computer training lab 15 30 16 00Coffee breakFlex Lab 16 00 18 00PracticalSession 1 continued Single Particle Analysis RelionSession 2 continued Single Particle Analysis cisTEMSession 3 continued Single Particle Analysis cryoSPARCSession 4 continued Subtomo Analysis IC 15 125IC 15 114IC 15 104Computer training lab 18 00 19 00DinnerCanteen19 00 21 00Student presentations IVRooftop lounge21 15Shuttle to ISG HotelBus stop Day 5 Thursday 25 August 2022 TimeSpeakersLocation08 35Shuttle to EMBL ISG bus stop 08 50 09 00Overview of the dayCourtyard Room09 00 10 00Automation of single particle EM Bridget Carragher New York Structural Biology Center USACourtyard Room 10 00 11 00Atomic model building and validationFrank DiMaio University of Washington USACourtyard Room 11 00 12 00 Panel discussionDiscussion leader Henning Stahlberg EPFL SwitzerlandCourtyard Room12 00 13 00Lunch breakCanteen13 00 15 30PracticalSession 1 continued Single Particle Analysis RelionSession 2 continued Single Particle Analysis cisTEMSession 3 continued Single Particle Analysis cryoSPARCSession 4 continued Subtomo AnalysisIC 15 114IC 15 104IC 15 125Computer training lab 15 30 16 00Coffee breakFlex Lab 16 00 18 30PracticalSession 1 continued Single Particle Analysis RelionSession 2 continued Single Particle Analysis cisTEMSession 3 continued Single Particle Analysis cryoSPARCSession 4 continued Subtomo Analysis IC 15 114IC 15 104IC 15 125Computer training lab 18 30 19 30Preparation for practicals discussion Pizza dinnerRooftop lounge 19 30 20 00CryoEM in PharmaAlexis Rohou Genentech USA Rooftop lounge 20 00 21 00Discussion round Career Paths in academia facilities and industryRooftop lounge 21 00Walk to ISG Hotel Day 6 Friday 26 August 2022 TimeSpeakersLocation08 35Shuttle to EMBLISG bus stop 08 50 09 00Overview of the dayCourtyard Room 09 00 10 00Sample preparation for in situ cryo electron tomography FIB technology Phillip Erdmann Human Technopole ItalyCourtyard Room 10 00 11 00Particle localization and extraction in cryo electron tomogramsBeata Turonova Max Planck Institute of Biophysics Germany remote Courtyard Room 11 00 12 00 High resolution subtomogram analysis William Wan Vanderbilt University USACourtyard Room12 00 13 00Lunch breakCanteen13 00 13 15Group photo13 15 14 00Preparation for practical presentationCourtyard Room 14 00 16 00Practical discussionComparing methods tips and tricks and data interpretationDiscussion leader Sebastian Eustermann EMBL Heidelberg GermanyCourtyard Room 16 00 19 00City tour and free time19 30 21 00Downtown dinner Day 7 Saturday 27 August 2022 TimeSpeakersLocation08 35Shuttle to EBMLISG bus stop08 50 09 00Overview of the dayCourtyard Room09 00 10 00Correlative light and electron microscopy for Structural Cell BiologyWanda Kukulski University of Bern SwitzerlandCourtyard Room 10 00 10 30Sponsor presentations Thermo Fisher ScientificChristopher Schmid Martin Obr High Resolution and High Throughput Structural Biology with Electron Cryo TomographyCourtyard Room 10 30 11 00Sponsor presentations CryoSolGiulia Weissenberger VitroJet Moving sample preparation into a new eraCourtyard Room 11 00 12 00 Panel discussionDiscussion leader Julia Mahamid EMBL Heidelberg Germany Courtyard Room12 00 13 00Lunch breakCanteen13 00 15 30PracticalSession 5 Single Particle Analysis RelionSession 6 Single Particle Analysis cisTEMSession 7 Single Particle Analysis cryoSPARCSession 8 Subtomo AnalysisSession 9 Model BuildingSession 10 Microscopy and DemosIC 15 104IC 15 114IC 15 125Computer training lab Helix seminar room B01 Imaging centre15 30 16 00Coffee breakFlex Lab 16 00 18 00PracticalSession 5 continued Single Particle Analysis RelionSession 6 continued Single Particle Analysis cisTEMSession 7 continued Single Particle Analysis cryoSPARCSession 8 continued Subtomo AnalysisSession 9 continued Model BuildingSession 10 continued Microscopy and Demos IC 15 104IC 15 114IC 15 125Computer training lab Helix seminar room B01 Imaging centre 18 00 18 30Coffee break Flex Lab 18 30 19 30PracticalSession 5 continued Single Particle Analysis RelionSession 6 continued Single Particle Analysis cisTEMSession 7 continued Single Particle Analysis cryoSPARCSession 8 continued Subtomo AnalysisSession 9 continued Model BuildingIC 15 104IC 15 114IC 15 125Computer training lab Helix seminar room B01 19 30 20 00Walk to ISG Hotel20 00 21 30Dinner and continued discussionISG hotel Day 8 Sunday 28 August 2022 TimeSpeakersLocation08 35Shuttle to EMBLISG bus stop08 50 09 00Overview of the dayCourtyard Room 09 00 09 30Sponsor presentations Oxford InstrumentsCourtyard Room 09 30 10 00Sponsor presentations GatanCourtyard Room 10 00 10 30Coffee breakFlex lab10 30 12 30PracticalSession 5 continued Single Particle Analysis RelionSession 6 continued Single Particle Analysis cisTEMSession 7 continued Single Particle Analysis cryoSPARCSession 8 continued Subtomo AnalysisSession 9 continued Model BuildingSession 10 continued Microscopy and Demos IC 15 104IC 15 114IC 15 125Computer training lab Helix seminar room B01 Imaging centre 12 30 13 30Lunch breakCanteen13 30 16 00PracticalSession 5 continued Single Particle Analysis RelionSession 6 continued Single Particle Analysis cisTEMSession 7 continued Single Particle Analysis cryoSPARCSession 8 continued Subtomo AnalysisSession 9 continued Model BuildingSession 10 continued Microscopy and DemosIC 15 104IC 15 114IC 15 125Computer training lab Helix seminar room B01 Imaging centre 16 00 16 30Coffee break Flex Lab 16 30 18 30PracticalSession 5 continued Single Particle Analysis RelionSession 6 continued Single Particle Analysis cisTEMSession 7 continued Single Particle Analysis cryoSPARCSession 8 continued Subtomo AnalysisSession 9 continued Model BuildingCourtyard Room Computer training labMeeting room B11Helix seminar room B01 Helix seminar room A0118 30 19 30DinnerCanteen19 30 20 30Discussion round Recent breakthroughs and emerging technologiesCourtyard Room20 30Walk to ISG Day 9 Monday 29 August 2022 TimeSpeakersLocation08 35Shuttle to EMBLISG bus stop08 50 09 00Overview of the dayCourtyard Room 09 00 09 30Sponsor presentation KleindiekCourtyard Room 09 30 10 30Fitting of low resolution EM maps and integrative structure determinationJan Kosinski EMBL Hamburg Germany Courtyard Room 10 30 11 30In cell Structural Biology Julia Mahamid EMBL Heidelberg GermanyCourtyard Room 11 30 12 00Coffee breakFlex lab12 00 13 00 Importance of Data Sharing structural databases and FAIR principlesArdan Patwardhan EMBL EBI Hinxton UK remote Courtyard Room13 00 14 00Wrap up with emphasis on the future of cryoEM responsible practice reporting and validation standardsCourtyard Room 14 00 14 30Packed lunch and departure14 30Bus to train stationBus stop Practical information Registration fees and motivation letter The course is limited to up to 24 participants For selection purposes please note that your application will not be considered without a letter of motivation Registration Registration fees include admission course materials COVID 19 safety measures meals and coffee breaks This EMBO course includes accommodation and transportation to and from the ISG Hotel to the venue Academia 500PhD Student 500Industry 1000 Confirmation and payment The registration fee should be paid only after acceptance to the course The results will be announced approximately 2 3 weeks after the application deadline Motivation letter submission After you have logged in and successfully registered you will receive an email asking you to submit your motivation letter Click on the link provided and enter your motivation letter in the text box provided Alternatively you can submit your motivation letter by clicking on the link on the confirmation page directly after registering Instructions Include your relevant skills experience and qualifications showing why you would be suitable for the course Explain why you would like to attend including what you can contribute and how you think you will benefit from the course Please note The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised For more detailed information follow the instructions provided in our video on how to submit a course motivation letter Further details For further information about registration and motivation letter submission please refer to the FAQ page Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of both registration fee waivers and travel grants Availability is limited to participants attending on site events in Heidelberg and will be indicated during the abstract or motivation letter submission process Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course or conference Travel grant The travel grant will cover the cost of travel airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Course EMBL Conference or EMBO EMBL Symposium from within Europe up to 1000 for participants travelling to an EMBL Course EMBL Conference or EMBO EMBL Symposium from outside Europe up to 500 for any participant travelling to an EMBO Practical Course or EMBO Workshop up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Practical Course or EMBO Workshop Registration fees are only covered for EMBO Practical Courses or EMBO WorkshopsThe organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare grant EMBO practical courses and workshops only For EMBO Practical Course or EMBO Workshop participants with children there is the possibility to apply for a childcare grant to offset child care costs incurred by participants or speakers when participating at a course or conference Eligible costs include fees for a baby sitter or child care facility travel costs for a care giver or travel costs for taking the child to the meeting etc Please note that priority will be given to early stage researchers A maximum amount of 500 EUR can be awarded per participant applying for an EMBO Childcare Grant In order to apply for this grant for EMBO Workshops you must be registered by the abstract submission deadline Application You may apply for financial assistance when submitting your motivation letter for courses and abstract for conferences In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application For the Boehringer Ingelheim Fonds Travel Grant there is a pre application question during the motivation letter submission process and if selected you will be requested to complete a standard form and documentation consisting of your travel expense estimation Selection The scientific organisers will select the recipients of all financial assistance during the motivation letter or abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection is based on your current work or study location the reasons for needing financial support and the impact this event will have on your career Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details View our list of external funding opportunities and information on attending a conference as an event reporter For further information about financial assistance please refer to the FAQ page Accommodation and shuttles Accommodation has been pre booked for you at the ISG Hotel for the default dates of 21 to 29 August 8 nights Please note that the course registration fee includes coverage of accommodation costs in twin rooms including breakfasts for your stay at the ISG but that you will be required to pay an additional cost of 21 EUR per night for a single room This should be paid by you directly to the ISG during your stay Any additional nights need to be booked and paid for by you We recommend that all course participants stay at the ISG Hotel which is the dedicated hotel for the course Local transport Shuttle buses will go from the ISG Hotel to EMBL and back mornings and evenings A bus schedule and location of the bus stops will be made available prior to the meeting Further details Address EMBL Heidelberg Meyerhofstra e 1 69117 Heidelberg GermanyFor further information on getting to EMBL Heidelberg visit our Travel Information page For enquiries about accommodation and local transportation please refer to the FAQ page Technical requirements and event software Event software The EMBL eCampus learning platform will be used to collaborate communicate and network with all of the course participants All participants will receive information on how to join shortly before the course We recommend using Chrome Safari or Mozilla Firefox browsers for eCampus Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page COVID 19 related questions COVID 19 information for on site events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage...

Julia Mahamid, Sebastian Eustermann, Simone Mattei, Lori Passmore, Henning Stahlberg

EMBO Practical Course

EMBL Heidelberg

18 July - 22 July 2022

Edit

July 11, 2022 00:002022CourseEMBL-EBI

Description This course will introduce and explore a number of key bioinformatics tools and resources that can be applied to T cell immunological research Targeted at life scientists with a wet lab focus it will provide participants with an overview of best practice methods in applying bioinformatics approaches and enable them to become confident users of their own and public domain data The resources introduced during the course will cover a variety of data types from genomic data to computational models and biological pathways Participants will gain experience of the analysis pipelines for RNA Seq and flow cytometry experiments as well as data integration of omics data and basics concepts of machine learning approaches This course has been developed in collaboration with the ENLIGHT TEN project a consortium focused on developing early stage research expertise in T cell immunology and big data analysis In person course We plan to deliver this course in an in person manner onsite at our training suite at EMBL EBI Hinxton Please be aware that we are continually evaluating the ongoing pandemic situation and as such may need to change the format of courses at short notice Your safety is paramount to us you can read our COVID guidance policy for more information All information is correct at time of publishing...

Sophie Spencer

EMBL-EBI

11 July - 13 July 2022

Microfluidics 2022

Edit

July 11, 2022 00:002022ConferenceEMBL Heidelberg, Virtual

Description OverviewSpeakersProgrammePractical informationSponsorsPre conference workshop Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Proof of COVID 19 vaccination or recovery is required for on site attendance Please see EMBL s COVID 19 terms and conditions For late poster submission please contact Iva Gavran Conference overview Microfluidic tools have made recent biological and biomedical research leaps possible At the physics engineering chemistry and biology interface innovation in microfluidic approaches has positively impacted areas as diverse as nucleotide sequencing functional genomics single cell and single molecule studies and biomedical diagnostics Many of these applications including next generation sequencing devices have been revolutionised by miniaturisation paving the way for global gene analysis and hence transforming biology Working on the pico to nanoliter scale not only allows a high degree of parallelisation but importantly offers superb spatiotemporal control Small objects such as cells or even discrete parts thereof can be exposed to unique conditions facilitating entirely novel approaches to inquiry in modern biology and chemistry The EMBL Microfluidics Conference brings together top researchers and emerging research leaders to spark scientific exchange and create community Topics spanning from fundamental physics chemistry to device design and nascent biological applications will be presented which should be of interest to everyone from experts in microfluidic design to users of the next generation of microfluidic tools and from academic scholars and trainees to industry colleagues Session topics Probing biologyNext generation device design and emerging applicationsDisease diagnostics analytical chemistry and chemical synthesisSingle cell and single molecule analyses What past participants say The Microfluidics conference has given me the opportunity to meet the authors of my favourite publications and to interact with the editors of the journals where I usually submit my work at This conference has allowed me to share my findings through posters and flash talks and it increased my scientific network Ana Pe aherrera Universidad Tecnol gica Nacional Buenos Aires Argentina The EMBL Microfluidics conference broadened my view of the microfluidics field It is very well organised with great lectures and inspiring discussions Yunhao Zhai from Centre d Immunologie Marseille Luminy Marseille France Speakers Charles Baroud Ecole Polytechnique France Anindita Basu University of Chicago USA Yoon Kyoung Cho IBS UNIST Republic of Korea Bart Deplancke EPFL Switzerland Elena Ferapontova Aarhus University Denmark Andreas Hierlemann ETH Z rich Switzerland Tomasz Kaminski University of Warsaw Poland Jina Ko University of Pennsylvania USA Sebastian Maerkl EPFL Switzerland Christoph Merten EPFL Switzerland Sumita Pennathur University of California Santa Barbara USA Steve Shih Concordia University Canada Aaron Streets University of California Berkeley USA Winnie Edith Svendsen Technical University of Denmark Denmark Yi Chin Toh Queensland University of Technology Australia Angela Wu The Hong Kong University of Science and Technology Hong Kong SAR China Scientific organisers Christoph Merten EPFL Switzerland Angela Wu The Hong Kong University of Science and Technology Hong Kong SAR China Conference organiser Iva Gavran Course and Conference Officer EMBL Heidelberg Germany Programme Got something to say Tweet it EMBLMicrofluidics Recorded talks will be accessible on demand for 2 weeks after the end of the event All times in the programme below are shown as the time in Europe Berlin Programme is subject to change Day 1 Monday 11 July 2022 TimeSpeaker11 15 13 00Registration and light lunch11 45 12 45Pre conference workshop registration required Location Flex Lab A B13 00 13 15Opening remarksSession 1 Probing biologyChairs Aaron Streets University of California Berkeley USA Sumita Pennathur University of California Santa Barbara USA 13 15 13 45Modeling cancer immune interactions in microfluidic dropletsCharles Baroud Ecole Polytechnique FranceTalk will be recorded and available on demand 13 45 14 15Engineering and measuring systemic multi organ interactionsYi Chin Toh Queensland University of Technology AustraliaTalk will be recorded and available on demand 14 15 14 30Microfluidics approach to study cells size dynamics andadhesion of Candida albicans Goliath cellsIana Kalinina Medical Research Council Centre forMedical Mycology University of Exeter United KingdomTalk will be recorded and available on demand 14 30 14 45A new microfluidic workflow to study the effects of spatiotemporal gradients in tumor microenvironmentsYanfang Li Technical University of Denmark DenmarkTalk will be recorded and available on demand14 45 15 15Coffee break and Meet the speakers15 15 15 45On biochemical constructors and synthetic cellsSebastian Maerkl EPFL SwitzerlandTalk will be recorded and available on demand 15 45 16 00Probing viscosity regulated Fallopian tube epithelial cell development and function for organ on chip applicationsMelati Suhaila Binti Abdul Halim Monash University AustraliaTalk will be recorded and available on demand 16 00 16 15Diverse polyclonal antibody therapeutic generation at GigaGenKyle Carter GigaGen USATalk will be recorded and available on demand 16 15 16 45Transcriptomic Analysis of 3D Vasculature On A Chip Reveals Paracrine Factors Affecting Vasculature Growth and MaturationAngela Wu The Hong Kong University of Science and Technology Hong Kong SAR ChinaTalk will be recorded and available on demand 16 45 17 15Coffee break and Meet the speakers17 15 18 45Poster Session 1 odd 18 45 20 15Dinner 20 15 21 45Networking drinks at the ATC Rooftop lounge Day 2 Tuesday 12 July 2022 TimeSpeakerSession 2 Next generation device design and emerging applicationsChairs Bart Deplancke EPFL Switzerland Anindita Basu University of Chicago USA 09 00 09 30Microfluidics for synthetic biologySteve Shih Concordia University CanadaTalk will be recorded and available on demand 09 30 10 00Hybrid soft hard materials for wearable microfluidic devicesSumita Pennathur University of California Santa Barbara USATalk will be recorded and available on demand 10 00 10 15Robust processing of multi step reactions in dropsHee Sun Han University of Illinois at Urbana Champaign United States of AmericaTalk will be recorded and available on demand10 15 10 30Microfluidic Sample Preparation of Mammoth Tooth Enamel for Amino Acid DatingLaila Patinglag Manchester Metropolitan University United Kingdom Talk will be recorded and available on demand 10 30 11 00Coffee break and Meet the speakers11 00 11 30Novel droplet microfluidic methods for multistep single cell RNA seq assaysTomasz Kaminski University of Warsaw PolandTalk will be recorded and available on demand 11 30 11 45Fed batch droplet nanobioreactor for controlled microbial growth a step towards screening under industrially relevant conditionsKartik Totlani Norwegian University of Science and Technology NorwayTalk will be recorded and available on demand 11 45 12 00Making microfluidics accessible through open high end low cost instrumentation designTobias Wenzel Catholic University of Chile ChileTalk will be recorded and available on demand 12 00 12 30Microphysiological systems featuring microfluidic and microsensor structuresAndreas Hierlemann ETH Z rich SwitzerlandTalk will be recorded and available on demand 12 30 14 00Lunch and Meet the speakersSession 3 Disease diagnostics analytical chemistry and chemical synthesisChairs Steve Shih Concordia University Canada Charles Baroud Ecole Polytechnique France 14 00 14 30Centrifugal microfluidics for liquid biopsy and beyondYoon Kyoung Cho Ulsan National Instituteof Science and Technology Republic of KoreaTalk will be recorded and available on demand 14 30 15 00Bioelectronic platforms for cancer diagnosis andmonitoring treatment efficacyElena Ferapontova Aarhus University DenmarkTalk will be recorded and available on demand 15 00 15 15Microfluidic sample preparation for cryogenic electron microscopy from a single colony of cell cultureGangadhar Eluru Flanders Institute for Biotechnology VIB BelgiumTalk will be recorded and available on demand 15 15 15 30Barrier free paper analytical devices for multiplex colorimetric detectionAyushi Chauhan Indian Institute of Science IndiaTalk will be recorded and available on demand 15 30 16 30Coffee break and Meet the speakers16 30 16 45Microfluidics for complete simulation of the human gastrointestinal tractMiguel Xavier International Iberian Nanotechnology Laboratory PortugalTalk will be recorded and available on demand 16 45 17 00A low cost paper based sample preparation module to lyse bacterial cells and extract genomic DNA using isotachophoresisShruti Soni Indian Institute of Science India Talk will be recorded and available on demand 17 00 17 30Droplet microfluidics in personalized cancer therapy and immune repertoire screeningChristoph Merten EPFL SwitzerlandTalk will be recorded and available on demand 17 30 18 00Coffee break and Meet the speakers18 00 19 30Poster Session 2 even 19 30 21 00BBQ dinner21 00 22 30Networking drinks and live music Day 3 Wednesday 13 July 2022 TimeSpeaker09 00 12 30Session 4 Single cell and single molecule analysesChairs Angela Wu The Hong Kong University of Science and Technology Hong Kong SAR ChinaChristoph Merten EPFL Switzerland 09 00 09 30Engineering next generation single cellphenomic technologiesBart Deplancke EPFL SwitzerlandTalk will be recorded and available on demand 09 30 09 45Measuring detergent effect on RNA molecule capture in droplet based single cell transcriptomicsKarolis Goda Vilnius University Lithuania Talk will be recorded and available on demand 09 45 10 00Single cell barcoding using 2D microarrays combined with droplet based microfluidics for precise and informed identification of drug candidatesKarolis Simutis ESPCI France Talk will be livestreamed 10 00 10 30New opportunities in translational research bring new devices and new applicationsAnindita Basu University of Chicago USATalk will be recorded and available on demand 10 30 11 00Coffee break and Meet the speakers11 00 11 30Microtechnology based Single Cell and EV ProfilingJina Ko University of Pennsylvania USATalk will be recorded and available on demand11 30 11 45Multiplexed Droplet Array Chip for Single cell Multi omics ProfilingXuyan Lin The Hong Kong University of Science and Technology Hong Kong SAR ChinaTalk will be recorded and available on demand 11 45 12 00Single cell high throughput measurement of the memory B cell immune repertoireLorenzo Zolfanelli ESPCI Institut Pasteur France Talk will be recorded and available on demand 12 00 12 30New methods for multimodal measurement of single cellsAaron Streets University of California Berkeley USATalk will be recorded and available on demand 12 30 12 45Closing session and poster prizes12 45 13 15Packed Lunches Departure Practical information Registration fees and abstract submission On site registration fees include admission conference materials COVID 19 safety measures meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Virtual registration fees include access to all of the talks livestreamed and on demand and facility to submit questions On site Academia 710On site PhD Student 610On site Industry 910Virtual Academia 175Virtual PhD Student 125Virtual Industry 225 NO visa support letters will be issued until payment of the registration fee is confirmed Accredited journalists may be eligible to register for complimentary press registration Registrants may be required to provide accreditation or equivalent proof of press membership after registration Please contact Iva Gavran for more information Please note that we do not offer complimentary registrations for editors of scientific journals Confirmation and payment Registration will be on a first come first served basis Your place can only be confirmed after payment of the registration fee If you are added to our waiting list please consider taking advantage of our offerings to participate virtually On site participants Types of payments accepted are international bank transfers and credit card payments Virtual participants We are only able to accept card payments In exceptional cases we can accept bank transfers Please contact events embl de for details Abstract submission Abstracts will not be accepted from virtual participants Only registered participants attending the on site event are eligible to submit an abstract After you have logged in and successfully registered you will receive an email asking you to submit your abstract Click on the link provided and enter your abstract in the text box provided Alternatively you can submit your abstract by clicking on the link on the confirmation page directly after registering The same login credentials are used for both processes Please note Title The title should not exceed 20 words Only the first word of the title should start with a capital letter and the rest of the title should be in lowercase Authors and Affiliations Please fill in the author s details as requested in the online form The compulsory details are First Name Last Name Organisation Name Affiliation or Company Country and Email Mark only one author as the role of First author and please don t forget to indicate who will be presenting The order of the authors will be listed as follows First Author Co First Author alphabetically if multiple co author s in the order added by the submitter Presentation Types When submitting your abstract you can apply for an oral or poster presentation A selection process will take place with the results announced 2 3 weeks after the abstract submission deadline Please check our FAQs pages for further information on how to submit an abstract Financial assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of both registration fee waivers and travel grants Availability is limited to participants attending on site events in Heidelberg and will be indicated during the abstract or motivation letter submission process Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course or conference Travel grant The travel grant will cover the cost of travel airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Course EMBL Conference or EMBO EMBL Symposium from within Europe up to 1000 for participants travelling to an EMBL Course EMBL Conference or EMBO EMBL Symposium from outside Europe up to 500 for any participant travelling to an EMBO Practical Course or EMBO Workshop up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Practical Course or EMBO Workshop Registration fees are only covered for EMBO Practical Courses or EMBO WorkshopsThe organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Application You may apply for financial assistance when submitting your abstract for conferences In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Selection The scientific organisers will select the recipients of all financial assistance during the motivation letter or abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection is based on your current work or study location the reasons for needing financial support and the impact this event will have on your career Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details See our list of external funding opportunities and information on attending a conference as an event reporter For further information about financial assistance please refer to the FAQ page Accommodation and shuttles Accommodation is not included in the conference registration fee As further changes in our events are possible due to COVID 19 you should book flights trains and hotels with flexible options and favourable cancellation conditions The hotels below have rooms on hold for participants until Friday 10 June 2022 in some cases at special rates Please quote the booking code MCF22 01 and confirm the exact price of the room with the hotel directly Hotel AnlageHotel ibis HeidelbergPremier Inn Heidelberg CityHotel Bayrischer Hof ISG Hotel Staycity Aparthotel HeidelbergB B HotelLeonardo Hotel Heidelberg City CentreSteffi s Hostel HeidelbergExzellenz Hotel Boarding HouseMeininger HeidelbergHotel Vier Jahreszeiten HeidelbergHotel Holl nder Hof Hotel Monpti Conference shuttle buses Conference shuttle buses are free of charge for participants and depart from designated bus stops near the hotels to EMBL and back mornings and evenings Download the bus schedule The bus stops for this conference are Kurf rsten Anlage opposite Main Train Station Hotel Premier Kurf rsten Anlage 23Leonardo Hotel Bergheimer Str Neckarm nzplatzPeterskircheISG Hotel View Conference shuttle bus stops and hotels in a larger map Please note that not every bus stop will be used for every event Further details Address EMBL Meyerhofstra e 1 69117 Heidelberg Germany For further information on getting to EMBL Heidelberg visit Public Transportation to the Venue For information about accommodation and local transportation please refer to the FAQ page On site information Catering All meals and coffee breaks are included in the registration fee Our catering staff will prepare a wide variety of vegetarian meals meat and fish dishes soups pasta fresh fruit and vegetables as well as a variety of desserts Please wear your badge at all times when serving yourself No food or drinks are allowed in the auditorium Charging lockers There are lockers available next to the stairs leading down into the Auditorium You will find some of those equipped with sockets to charge your smartphone tablet etc Electricity and charging station In most places the electricity is 220 volts AC 50 cycles An adaptor and a plug that fits the German socket may be needed for your appliances laptop i e American Japanese etc A USB charging station for electronic devices is available at the registration desk EMBL merchandise EMBL Merchandise is available on Mon Thu 9 am 12 pm If you are interested in purchasing an EMBL souvenir products presented in the glass display in the registration area please ask at the registration desk for more information Health and safety notes Please read EMBL s COVID 19 terms and conditions for events Do not smoke in any EMBL building Eating and drinking is prohibited in the Auditorium and all laboratories Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required The first aid room is located next to the ATC Registration Desk room 10 205 Dial the Emergency number 222 from any EMBL internal phone only Where is the accident What happened How many injured Emergency number 06221 387 7821 from mobile phones Please report all accidents to the conference officer at the registration desk In case of fire Press the nearest fire alarm button or the Emergency number 222 from any internal phone A loud fire alarm will go off if an evacuation is required On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting pointsDo not use the lifts Beyond first aid Please remember to bring your own medication if needed to the conference Note that the next pharmacy is a 4 minute drive from the EMBL but for many medications you will be required to see a doctor to get a prescription Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg In any case the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary Internet Wi Fi is available everywhere on the premises no password required just log on to ATC Guest The eduroam network secure world wide roaming access service developed for the international research and education community is also available Lost and found Lost and Found are kept at the registration desk until the end of the conference Luggage There are lockers available on site to store your luggage which require a 2 EURO coin to operate There is another luggage room on level E0 which is free to use but remains unlocked during the conference Nursing room There is a nursing room available in the ATC Rooftop Lounge on level A29 Photography During the conference an EMBL Photographer may be taking photographs If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Printing We can help printing your boarding passes train ticket Please send it to events embl de and collect your print outs at the registration desk Room for prayer yoga and meditation There is a room for prayer mediation and yoga located on level E0 behind the Auditorium Please be respectful of other participants using the room Sightseeing A variety of activities in Heidelberg can be found on this website www heidelberg marketing com Travel to and from the venue During the event we provide conference shuttle busses to and from EMBL In addition there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time Information on the conference shuttle busses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page Useful German expressions EnglishGermanHelloHalloGoodbyeAuf WiedersehenGood morningGuten MorgenGood afternoonGuten TagGood eveningGuten AbendGood nightGute NachtI m sorryTut mir leidExcuse me Entschuldigen SieHow are you Wie geht s I m fine thanks And you Mir geht es gut danke und dir Ihnen What is your nameWie heisst du Wie heissen Sie My name isIch heisseDo you speak EnglishSprechen Sie Englisch I don t understandIch verstehe nichtPlease speak more slowlyK nnen Sie bitte langsamer sprechenThank youDanke sch nWhere is the toilet Wo ist die Toilette Please call me a taxiBitte rufen Sie mir ein TaxiHow do I get to Wie komme ich zum zur A beer two beers pleaseEin Bier zwei Bier bitteA glass of red white wine pleaseEin Glas Rot Weisswein bitteThe menu pleaseDie Speisekarte bitteIs there a local speciality Gibt es eine Spezialit t aus dieser Gegend I m VegetarianIch bin VegetarierIt was deliciousEs war hervorragendThe bill pleaseDie Rechnung bitteI have a headacheIch habe KopfschmerzenI have a sore throatIch habe HalsschmerzenMy stomach hurtsIch habe MagenschmerzenI m allergic toIch bin allergisch gegenI need a doctor who speaks EnglishGibt es einen Arzt der Englisch spricht Virtual participation What s included Access to all the livestreamed talksVideo library of the recorded talks during and after the eventFacility to submit questions Please note that only on site participants are able to submit abstracts and participate in the poster sessions Event platform We are using an event platform for this conference More information about the platform will be shared ahead of the conference Guidelines Do not broadcast the conference to unregistered participants You are encouraged to tweet and post about the event Tweet unless the speaker specifically says otherwise but be mindful of unpublished data Please do not capture transmit or redistribute data presented at the meeting Additional information can be found in our Code of Conduct Health and well being It is important to stay healthy and move around especially when you are attending an event virtually We have put together a few coffee break stretches and yoga videos in the conference platform for you to enjoy during the event How to ask questions Please use the Q A function in the event platform If you have any other questions you can go to the Help Desk in the event platform Click on more on the top menu and click Help Desk Time zone The programme is planned based on the Europe Berlin time zone unless otherwise stated Please take your time zone into consideration when planning your attendance Additional information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page COVID 19 related questions COVID 19 information for onsite events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Silver sponsor Bronze sponsor Media partners Analyst a Royal Society of Chemistry journal Analytical Methods a Royal Society of Chemistry journal Angewandte Chemie a Wiley journal ChemBioChem a Wiley journal EMBO Journal an EMBO Press journal FEBS Open Bio a FEBS Press journal International Union of Biochemistry and Molecular Biology Lab on a Chip a Royal Society of Chemistry journal Open Biology a Royal Society journal Sensors Diagnostics a Royal Society of Chemistry journal Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information on sponsoring possibilities If you are interested in becoming a media partner of this event please visit our media partnerships webpage Pre conference workshop Industry webinar will be hosted by the sponsoring company Droplet Genomics prior to the virtual EMBL Conference Microfluidics 2022 on Monday 11 July Participation in this webinar is free of charge for registered conference attendees The number of available places is limited first come first served All registered conference attendees will receive an email with a registration link ABSTRACT Breaking barriers of droplet microfluidics efficient multi step workflows with single cells Speaker Rapolas Zilionis CSO of Droplet Genomics Compartmentalization of cells into picoliter sized droplets has already led to the burst of single cell sequencing applications and the development of novel approaches for high throughput functional screening Nevertheless many sample types and molecular biology techniques require multi step processing Droplets are amenable to reagent addition via droplet merging or picoinjection however full reagent exchange is not possible To tackle the challenge posed by multi step workflows the Droplet Genomics team has developed a new compartmentalization approach based on hollow hydrogel shells with liquid cores This webinar will discuss how semi permeable capsules SPCs enable the exchange of buffers enzymes and small compounds while retaining the cells and large biomolecules such as genomic DNA and mRNA compartmentalized During the workshop Droplet Genomics will show how SPCs are made and what new prospects are they promising for single cell genomics cell cultivation and phenotyping applications...

Christoph Merten, Angela Wu

EMBL Conference

EMBL Heidelberg, Virtual

8 July - 15 July 2022

Super-resolution microscopy: time-resolved STED nanoscopy

Edit

July 08, 2022 00:002022CourseVirtual

Description OverviewSpeakersProgrammePractical InformationSponsors Overview EMBL is committed to sharing research advances and sustaining scientific interaction throughout the coronavirus pandemic We are delighted to announce that the course is going virtual and invite you to join us online Course Overview This six day comprehensive microscopy course focuses on stimulated emission depletion microscopy STED and its application to biological questions Through lectures tutorials demonstrations and practical workshops the course provides in depth knowledge on all aspects of STED Nanoscopy It covers the fundamentals of STED microscopy different technical implementations and has a strong emphasis on sample preparation including choice of fluorophores and refractive index matching as well as image acquisition strategies for fixed samples and living cells Students will have the opportunity for exercises on state of the art STED microscopes in which they will acquire high quality nanoscopy data The faculty consists of Invited guest researchers experts from the EMBL and Leica Microsystems Audience This course is designed for researchers at the early stages of their career in the life sciences e g pre or postdoctoral level ideally with access to a STED microscope The participants should have an immediate need to apply the trained skills for their biological questions The course is strongly centered on practical aspects of STED microscopy and is therefore especially suited for people who rely on STED nanoscopy for their research Modules Resources The course will cover the entire range of skills needed to apply STED nanoscopy in biology The following topics will be covered in lectures tutorials as well as in practical workshops Sample preparation for STED microscopy including choice of fluorophores and refractive index matchingTechnical implementations CW STED pulsed STED gated STED time resolved STED tauSTED Multi Color 2D and 3D STED microscopyImage acquisition strategies for live cell STED Learning Outcomes At the end of the course the participants will be able to design experiments using STED microscopy prepare high quality microscopy samples and acquire state of the art nanoscopy images This course is organised in cooperation with Leica Microsystems What Past Participants Say About the Course A well organised course with a good balance of brilliant workshops pre recorded talks tutorials discussions and fun parts Although this was held in a virtual format it offered the opportunity to operate control the system software remotely The course helped me to deepen and expand my knowledge in super resolution microscopy especially STED and to further optimise and improve my experiments Daniela Bender Paul Ehrlich Institut Germany Speakers Speakers and Trainers Luis Alvarez Leica Microsystems Germany Niccol Banterle EMBL Heidelberg Germany Magalie Benard University of Rouen Normandy France Francesca Bottanelli Freie University Berlin Germany Giovanna Coceano KTH Royal Institute of Technology Stockholm Sweden Jana D hner University of Zurich Switzerland Michelle Frei University of California San Diego USA Merle Hantsche Grininger EMBL Heidelberg Germany Mike Heilemann Goethe University Frankfurt Germany Kai Johnsson Max Planck Institute for Medical Research Germany Antje Keppler EMBL Heidelberg Germany Marko Lampe EMBL Heidelberg Germany Ivana Niki Spiegel University of T bingen Germany Julia Roberti Leica Microsystems CMS GmbH Germany Ulf Schwarz Leica Microsystems CMS GmbH Germany Damien Shapman University of Rouen Normandy France Alexander Stockhammer Freie University Berlin Germany David Unnersj Jess University of Cologne Germany Giuseppe Vicidomini Italian Institute of Technology Italy Scientific Organisers Marko Lampe EMBL Heidelberg Germany Julia Roberti Leica Microsystems CMS GmbH Germany Ulf Schwarz Leica Microsystems CMS GmbH Germany Course Organisers Inna B sselmann Course and Conference Manager EMBL Heidelberg Germany Irena Provaznikova Training Lab Technician EMBL Heidelberg Germany Programme Got something to say Tweet it with EMBLSuperResolution The virtual course will start on Friday 8 July with an onboarding and introduction session The course will continue on Monday 11 July and finish on Friday 15 July with the regular programme Full time attendance is required for the course duration Participants will be required to view the pre recorded talks prior to the main start of the course The course will include live and pre recorded talks interactive discussion sessions online practicals hands on exercises and networking Information on the live stream and access to the course platform will be provided shortly before the start of the event In order to accommodate different time zones Workshop Groups 1 2 will always be scheduled in the afternoon CEST and Groups 3 4 always in the morning CEST All times in the programme below are shown as the time in Europe Berlin Amsterdam Paris To find out the equivalent time zone in your location enter Berlin the CEST programme time and your city into the Time Zone Converter Day 0 Friday 8 July 2022 Time CEST Session12 30 12 45Check in and house notesMarko Lampe EMBL Heidelberg Germany 12 45 13 00Welcome and course overviewMarko Lampe EMBL Heidelberg GermanyUlf Schwarz Leica Microsystems CMS GmbH Germany13 00 13 30Q A Pre Course Material Introduction to WorkshopsMarko Lampe EMBL Heidelberg GermanyUlf Schwarz Leica Microsystems CMS GmbH Germany13 30 14 30Flash Talks Part 114 30 14 45Break14 45 15 45Flash Talks Part 2 15 45 16 30 Virtual Social Programme Bar Mixer Day 1 Monday 11 July 2022 Time CEST Session12 30 12 45Check in and overview of the day12 45 13 30Introduction to STED MicroscopyMarko Lampe EMBL Heidelberg GermanyUlf Schwarz Leica Microsystems CMS GmbH Germany13 30 14 15Niccol Banterle EMBL Heidelberg Germany14 15 14 30Break14 30 15 15Super resolution imaging of the kidney filter using advanced sample preparationDavid Unnersj Jess University of Cologne Germany15 15 16 00New fluorescent probes for live cell imagingKai Johnsson Max Planck Institute for Medical Research Germany16 00 16 30 Break16 30 18 30WS 1 Multi Color STED Imaging of fixed samples Group 1Trainers Marko Lampe Luis Alvarez Jana D hnerWS 2 Imaging of Cleared tissue ExM STED Group 2Trainers Ulf Schwarz David Unnersj Jess Day 2 Tuesday 12 July 2022 Time CEST Session10 00 12 00WS 1 Multi Color STED Imaging of fixed samples Group 3Trainers Marko Lampe Luis Alvarez Jana D hner WS 2 Imaging of Cleared tissue ExM STED Group 4 Trainers Ulf Schwarz David Unnersj Jess 12 00 12 30 Break12 30 12 45Check in and overview of the day12 45 13 30Studying the structure of chromosomes and NPCs in single human cells by super resolution microscopyKai Sandvold Beckwith EMBL Heidelberg Germany13 30 14 15Optimization of protocols and image acquisition strategies for live cell tauSTEDMagalie Benard Damien Schapman University of Rouen Normandy France14 15 14 30Break14 30 15 15TauSTED pushing STED beyond its limits with a lifetimeUlf Schwarz Leica Microsystems Germany15 15 16 00Virtual Social Programme Speed networking 16 00 16 30Break16 30 18 30WS 1 Multi Color STED Imaging of fixed samples Group 1Trainers Marko Lampe Luis Alvarez Jana D hnerWS 2 Imaging of Cleared tissue ExM STED Group 2Trainers Ulf Schwarz David Unnersj Jess Day 3 Wednesday 13 July 2022 Time CEST Session10 00 12 00 WS 1 Multi Color STED Imaging of fixed samples Group 4Trainers Marko Lampe Luis Alvarez Jana D hner WS 2 Imaging of Cleared tissue ExM STED Group 3Trainers Ulf Schwarz David Unnersj Jess 12 00 12 30Break12 30 12 45Check in and overview of the day 12 45 13 30pre recorded talkGiuseppe Vicidomini Italian Institute of Technology Italy13 30 14 15Investigating cellular logistics with live cell STEDFrancesca Bottanelli Freie Universit t Berlin Germany14 15 14 30Break14 30 15 00Tutorial Sample Preparation 1 Refractive Index Matching and OpticsUlf Schwarz Leica Microsystems CMS GmbH Germany15 00 15 15EuroBioImaging Opportunities for ResearchersAntje Keppler Euro BioImaging Bio Hub EMBL Heidelberg Germany15 15 16 00Virtual Social Programme Online pictionary 16 00 16 30Break 16 30 18 30 WS 3 Live cell imaging Group 1Trainers Ulf Schwarz Luis Alvarez WS 4 Advanced STED Imaging Group 2Trainers Marko Lampe Alexander Stockhammer Day 4 Thursday 14 July 2022 Time CEST Session10 00 12 00 WS 3 Live cell imaging Group 3Trainers Ulf Schwarz Luis AlvarezWS 4 Advanced live cell STED Imaging Group 4Trainers Marko Lampe Alexander Stockhammer 12 00 12 30Break12 30 12 45Check in and overview of the day12 45 13 30Characterization of organelle dynamics with live cell nanoscopyGiovanna Coceano KTH Royal Institute of Technology Stockholm Sweden13 30 14 15Tutorial Sample Preparation 2 Fluorophores and stainingJana D hner University of Zurich SwitzerlandMarko Lampe EMBL Heidelberg Germany14 15 14 30Break14 30 15 15Exchangeable fluorophore labels in super resolution fluorescence microscopyMike Heilemann Goethe University Frankfurt Germany15 15 16 00Virtual Social Programme Bar Mixer16 00 16 30Break16 30 18 30 WS 3 Live cell imaging Group 2Trainers Ulf Schwarz Luis Alvarez WS 4 Advanced STED Imaging Group 1Trainers Marko Lampe Alexander Stockhammer Day 5 Friday 15 July 2022 Time CEST Session10 30 12 00WS 3 Live cell imaging Group 4Trainers Ulf Schwarz Luis Alvarez WS 4 Advanced STED Imaging Group 3Trainers Marko Lampe Alexander Stockhammer 12 00 12 30Break12 30 12 45Check in and overview of the day12 45 13 30 Minimal click chemistry based genetically encoded tags for fluorescent protein labeling in living cellsIvana Niki Spiegel University of T bingen Germany13 30 14 15Tutorial Sample Preparation 3 Fixation strategy and sample mountingJana D hner University of Zurich Switzerland Marko Lampe EMBL Heidelberg Germany14 15 14 30Break14 30 15 00Discussion rounds15 00 15 25 Correlative Light and Electron MicroscopyJana D hner University of Zurich Switzerland15 25 15 50Live cell labelling a chemical perspectiveMichelle Frei University of California San Diego USA15 50 16 15Closing remarks comments farewell and group photo Practical Information Registration Fees and Motivation Letter The course is limited to 20 participants For selection purposes please note that your application will not be considered without a letter of motivation Registration Registration Fees include admission and all course materials Academia 125PhD Student 125Industry 250 Confirmation and Payment The registration fee should be paid only after acceptance to the course The results will be announced approximately 2 3 weeks after the application deadline Motivation Letter Submission After you have logged in and successfully registered you will receive an email asking you to submit your motivation letter Click on the link provided and enter your motivation letter in the text box provided Alternatively you can submit your motivation letter by clicking on the link on the confirmation page directly after registering Instructions Include your relevant skills experience and qualifications showing why you would be suitable for the course Explain why you would like to attend including what you can contribute and how you think you will benefit from the course Please note The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised For more detailed information follow the instructions provided in our video on how to submit a course motivation letter Further Details For further information about registration and motivation letter submission please refer to the FAQ page Financial Assistance Financial Assistance Registration Fee Waivers All academic and student registrants are invited to apply for a registration fee waiver provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO The registration fee waiver covers the registration sum that you have paid to attend the meeting Conference participants are not required to pre pay the registration fee to be selected for a fee waiver for a virtual meeting If you have already paid the registration fee and are awarded a fee waiver it will be reimbursed after the meeting Course participants are required to pay the course fee in advance which will then be reimbursed after the recipient has attended the course Boehringer Ingelheim Fonds Travel Grant Applies to selected courses only Availability will be indicated during the abstract or motivation letter submission process This grant covers costs related to your attendance to the course registration travel and accommodation costs The grant is restricted to PhD students and postdocs who conduct basic biomedical research Whether you are eligible to apply for a travel grant depends on when you received your university entrance qualification e g Abitur A Levels High School Diploma Final State Examination for PhD and MD students as well as graduates the university entrance qualification must not have been obtained more than 11 years ago at the time of the envisaged course for postdocs the university entrance qualification must not have been obtained more than 13 years ago at the time of the envisaged course Application Applications for financial assistance can be submitted via the submission portal for the submission of abstracts for conferences or the submission of motivation letters for courses by completing the Financial Assistance Application Section underneath the section for entering abstract motivation letter information The link to the portal can be found in the registration confirmation email that you will receive after registering for the conference or course For conferences if you are not submitting an abstract you can still apply for financial assistance in the submission portal Read the instructions on how to apply for financial assistance Note that priority will be given to those submitting an abstract to present at the conference In your application you will be asked to answer questions regarding your motivation for applying and for registration fee waivers the reasons why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application For some events applications for Childcare Grants will still be done by email Information about the grant will be sent out shortly after the abstract motivation letter deadline Please contact the event Conference Officer if you have any questions Selection The scientific organisers will select the recipients of registration fee waivers during the abstract selection process for conferences and the participant selection process for courses Results will be announced approximately 3 4 weeks before the event start date Selection results do not impact your admission to the meeting Registration fee waiver selection is based on your current work or study location your motivation for applying the reasons for needing financial support and the impact this event will have on your career Childcare grants are allocated based on career stage with priority given to early stage researchers Further details Check out this list of external funding opportunities or get more information on attending the conference as an event reporter For further information about financial assistance please refer to the FAQ page Technical Requirements General The EMBL eCampus learning platform will be used to collaborate communicate and network with all of the course participants All participants will receive information on how to join shortly before the course We recommend using Chrome Safari or Mozilla Firefox browsers for eCampus Zoom will be used during the course for the live discussion and feedback sessions and the course practicals and networking More information will be provided closer to the start of the course Internet requirements Client computer with fast and stable internet access for the live virtual sessions Minimum 50 mbit download and 10 mbit uploadPreferred 100 mbit download and upload at your host institute Please note that it is recommended to use two computer screens Headsets is highly recommended for improved voice clarity and better audio Additional Information Please find additional information including FAQs and terms and conditions on our Information for Participants page Sponsors Sponsorship Opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other events or contact sponsorship embl de for further information...

Marco Lampe, Rainer Pepperkok, Ulf Schwarz

EMBL Course

Virtual

4 July - 8 July 2022

Systems biology: from large datasets to biological insight

Edit

July 04, 2022 00:002022CourseEMBL-EBI

Meredith Willmott

EMBL-EBI

4 July - 15 July 2022

Visualising life – interdisciplinary approaches to biology

Edit

July 04, 2022 00:002022CourseEMBL Heidelberg

...

EMBL Lautenschlaeger Summer School 2022

EMBL Heidelberg

29 June - 1 July 2022

Timing mechanisms linking development and evolution

Edit

Edit

June 19, 2022 00:002022ConferenceEMBL Heidelberg, Virtual

Description OverviewSpeakersProgrammePractical informationSponsorsAbout Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Proof of COVID 19 vaccination or recovery is required for on site attendance Please see EMBL s COVID 19 terms and conditions Late on site registration is still possible For information please contact Maria Bacadare Symposium overview This symposium will bring together researchers from diverse fields to enhance our understanding of the dissemination and metastatic colonisation of tumour cells It will provide a unique opportunity for interdisciplinary exchange on current approaches and future collaborations on metastasis and its therapeutic challenges Session topics Metastasis initiating cells circulating tumour cellsMotility and invasionTranscriptional and epigenetic control of metastasisMetastasis heterogeneity EMT and plasticityMetastasis signalling and latencyMetastasis imaging tumour microenvironment and immune evasion Speakers Keynote speakers Frederic de Sauvage Genentech USA Johanna Joyce University of Lausanne Switzerland Speakers Nicola Aceto ETH Z rich Switzerland Samuel Bakhoum Memorial Sloan Kettering Cancer Center USA Eduard Batlle Institute for Research in Biomedicine Spain Adrienne A Boire Memorial Sloan Kettering Cancer Center USA Thomas Brabletz Friedrich Alexander Universit t Erlangen N rnberg Germany Andrew J Ewald Johns Hopkins University School of Medicine USA Mariam Jamal Hanjani University College London UK Scott W Lowe Memorial Sloan Kettering Cancer Center USA Laura Machesky The Beatson Institute for Cancer Research UK Joan Massagu Memorial Sloan Kettering Cancer Center USA Nicholas McGranahan University College London UK Anna Obenauf Research Institute of Molecular Pathology IMP Austria Erik Sahai The Francis Crick Institute UK Charles Swanton The Francis Crick Institute UK Samra Turajlic The Francis Crick Institute UK Manuel Valiente Spanish National Cancer Research Center CNIO Spain Scientific organisers Johanna Joyce University of Lausanne Switzerland Daniel Klimmeck The EMBO Journal Germany Joan Massagu Memorial Sloan Kettering Cancer Center USA Charles Swanton The Francis Crick Institute UK Conference officers Maria Mercedes Bacadare Goitia EMBL Heidelberg Germany Programme Got something to say Tweet it EESMetastasis Recorded talks will be accessible on demand for 2 weeks after the end of the event All times in the programme below are shown as the time in Europe Berlin Please find the poster listing here Day 1 Sunday 19 June TimeSpeaker12 00 13 30Registration and Lunch13 30 13 45Opening remarks by scientific organisers13 45 14 30Keynote lecture Microenvironmental Regulation of MetastasisJohanna Joyce University of Lausanne Ludwig Institute for Cancer Research SwitzerlandSession 1Chair Eduard Batlle Institute for Research in Biomedicine Spain14 30 15 00Dormancy and outbreak of metastasis initiating cellsJoan Massagu Memorial Sloan Kettering Cancer Center USA15 00 15 15Zeb1 expression in CAFs promotes distant metastasis in PDACIsabell Armstark Friedrich Alexander Universit t Erlangen N rnberg Germany15 15 15 30Identification of regulators of CRC metastasis via in vitro and in vivo CRISPR screens in an organoid based CRC mouse model M Andres Blanco University of Pennsylvania USAAVAILABLE ON DEMAND AFTER LIVE STREAM 15 30 16 15Coffee break and meet the speakers in ATC Foyer16 15 16 45Biology and Vulnerabilities of Circulating Tumor CellsNicola Aceto ETH Z rich SwitzerlandAVAILABLE ON DEMAND AFTER LIVE STREAM 16 45 17 00Eosinophils and adaptive immune cells cooperate to enhance response to immune checkpoint blockade in breast cancer Olga Blomberg Netherlands Cancer Institute The Netherlands17 00 17 15Cell viscoelasticity orchestrates intravascular and early steps of metastasisValentin Gensbittel INSERM U1109 CRBS Tumor Biomechanics Universit de Strasbourg FranceAVAILABLE ON DEMAND AFTER LIVE STREAM 17 15 17 45Modelling metastasis in the lungs and liverErik Sahai The Francis Crick Institute UK17 45 18 15Pre dinner drinks18 15 19 45Dinner in Canteen 19 45 21 00Social event Science Pub Quiz19 45 21 30After Dinner Drinks in the ATC Foyer Day 2 Monday 20 June TimeSpeakerSession 2Chair Erik Sahai The Francis Crick Institute UK 09 00 09 30Characterizing the metastatic seeding clone in lung cancer evolutionNicholas McGranahan University College London UK09 30 09 45Quiescence inducing 3D engineered matrix uncovers drug protective signaling pathway of dormant cancer cellsAmaia Cipitria Biodonostia Health Research Institute Spain09 45 10 00Reactivation of embryonic programs in tissue damage and cancerHassan Fazilaty University of Zurich SwitzerlandAVAILABLE ON DEMAND AFTER LIVE STREAM 10 00 10 15The NALCN channel regulates metastasis and non malignant cell disseminationEric Rahrmann University of Cambridge UK AVAILABLE ON DEMAND AFTER LIVE STREAM 10 15 10 45Coffee break and meet the speakers in ATC Foyer 10 45 11 00Mitochondrial RNA modifications from metabolism to metastasisSylvain Delaunay German Cancer Research Center DKFZ GermanyAVAILABLE ON DEMAND AFTER LIVE STREAM 11 00 11 15PAK2 dependency of mesenchymal colorectal cancer cells can be exploited to prevent tumour growth and metastasisPatricia Gomez Barila Amsterdam UMC The NetherlandsAVAILABLE ON DEMAND AFTER LIVE STREAM 11 15 11 45Cellular strategies and molecular mechanisms driving breast cancer metastasisAndrew Ewald Johns Hopkins University School of Medicine USAAVAILABLE ON DEMAND AFTER LIVE STREAM 11 45 12 00Flash talks 2 minutes 1 slide per talk 51 Natasja Costermans 59 Kathrin Fuchs 73 Maria Peiris Pages 81 Saba Sameri12 00 13 30Lunch12 30 13 30Panel discussion session Publishing science new challenges new opportunitiesPanelist Andrew Ewald Johns Hopkins University School of Medicine USA Daniel Klimmeck The EMBO Journal GermanyJoan Massagu Memorial Sloan Kettering Cancer Center USALise Roth EMBO Molecular Medicine Germany13 30 15 00Poster Session 1 odd numbers 15 00 15 45Coffee break and meet the speakers in ATC Foyer Session 3Chair Adrienne Boire Memorial Sloan Kettering Cancer Center USA15 45 16 15Tumor environment interactions during pancreatic cancer metastasisScott Lowe Memorial Sloan Kettering Cancer Center USAAVAILABLE ON DEMAND AFTER LIVE STREAM 16 15 16 45Cell migration and invasion in the pancreatic cancer microenvironmentLaura Machesky Cancer Research UK Beatson Institute UKAVAILABLE ON DEMAND AFTER LIVE STREAM 16 45 17 00Vascular aging limits metastasisAshik Ahmed Abdul Pari German Cancer Research Center DKFZ Germany17 00 17 30Role of Air Pollution in Lung Cancer Initiation Revisiting Tumour PromotersCharles Swanton The Francis Crick Institute UK17 30Free evening Day 3 Tuesday 21 June TimeSpeakerSession 4Chair Thomas Brabletz Friedrich Alexander Universit t Erlangen N rnberg Germany09 00 09 30NoStem cells immune evasion and metastasisin colorectal cancerEduard Batlle Institute for Research in Biomedicine Spain09 30 09 45Liver colonization by colorectal cancer metastases requires YAP controlled plasticity at the micrometastatic stageMaria C Heinz University Medical Center Utrecht The Netherlands AVAILABLE ON DEMAND AFTER LIVE STREAM 09 45 10 00Atrx loss induces a hybrid EMT phenotype tumour invasion and metastasisKevin Myant Edinburgh University United KingdomAVAILABLE ON DEMAND AFTER LIVE STREAM 10 00 10 30Towards rational combination therapies Understanding tumor evolution during therapy response and resistanceAnna Obenauf Research Institute of Molecular Pathology IMP Austria10 30 11 00Coffee break and meet the speakers in ATC Foyer 11 00 11 15The Curated Cancer Cell Atlas enables a comprehensive characterisation of the transcriptomic processes underlying metastasisMichael Tyler Weizmann Institute of Science IsraelAVAILABLE ON DEMAND AFTER LIVE STREAM 11 15 11 30The expression of L1CAM in metastasis initiating cells of lung adenocarcinomaPark Jin Suk Memorial Sloan Kettering Cancer Center United States of America11 30 12 00Rewiring brain response to metastasis into a source of therapeutic resistanceManuel Valiente Spanish National Cancer Research Center CNIO AVAILABLE ON DEMAND AFTER LIVE STREAM 12 00 13 30LunchSession 5Chair Frederic J de Sauvage Genentech USA13 30 14 00Chromosomal instability as a driver of cancer metastasisSamuel F Bakhoum Memorial Sloan Kettering Cancer Center USAAVAILABLE ON DEMAND AFTER LIVE STREAM 14 00 14 15Metastatic niche derived angiocrine Wnt ligands exploit susceptible methylation states to instruct tumour dormancyMoritz Jakab German Cancer Research Center GermanyAVAILABLE ON DEMAND AFTER LIVE STREAM 14 15 14 30Distinct Contributions of Partial and Full EMT to Breast Cancer MalignancyNami Sugiyama Matsuda University of Basel SwitzerlandAVAILABLE ON DEMAND AFTER LIVE STREAM 14 30 15 00Genetic and spatial properties of metastasising populationsSamra Turajlic The Francis Crick Institute UKAVAILABLE ON DEMAND AFTER LIVE STREAM 15 00 15 45Coffee break and meet the speakers in ATC Foyer 15 45 16 00Transcription factor NKX2 1 drives serine glycine synthesis addiction in cancerElien Heylen KU Leuven BelgiumAVAILABLE ON DEMAND AFTER LIVE STREAM 16 00 16 15Impairing flow mediated endothelial remodeling reduces extravasation of tumor cellsNa l Osmani INSERM U1109 CRBS Tumor Biomechanics Universit de Strasbourg FranceAVAILABLE ON DEMAND AFTER LIVE STREAM 16 15 16 30Recording metastatic lineage histories at single cell resolution Kamen Simeonov University of Pennsylvania United States of America16 30 17 00Cellular plasticity in cancer driving force and therapeutic targetThomas Brabletz Friedrich Alexander Universit t Erlangen N rnberg GermanyAVAILABLE ON DEMAND AFTER LIVE STREAM 17 00 17 15Flash talks 2 minutes 1 slide per talk 42 Petr Benes 46 Amani Bouzidi 48 Michael Br gger 56 Louise Dutton 82 Michela Serresi17 15 19 15Poster Session 2 even numbers 19 15 21 45BBQ Live Music Lazy Fur Day 4 Wednesday 22 June TimeSpeakerSession 6Chair Laura Machesky Cancer Research UK Beatson Institute UK09 00 09 30Metastatic cancer cells outcompete for scarce metabolic resources in the leptomeningesAdrienne Boire Memorial Sloan Kettering Cancer Center USAAVAILABLE ON DEMAND AFTER LIVE STREAM 09 30 09 45The H3K36 demethylase KDM2A is a multifunctional regulator of non small cell lung cancer metastasis Carolyn Kravitz Yale University USAAVAILABLE ON DEMAND AFTER LIVE STREAM 09 45 10 00Novel metabolic vulnerabilities in cancer metastasis Alpaslan Tasdogan University Hospital Essen Germany10 00 10 15Stromal Oncostatin M cytokine signalling promotes breast cancer progression and metastasis by reprogramming the tumour microenvironment Mar a Mu oz Caffarel Biodonostia Health Research Institute SpainAVAILABLE ON DEMAND AFTER LIVE STREAM 10 15 10 45Coffee break and meet the speakers in ATC Foyer 10 45 11 15Insights into cancer metastasis from the PEACE studyMariam Jamal Hanjani UCL London UK11 15 12 00Keynote lecture Targeting stem cells and the Wnt pathway in colorectal cancerFrederic J de Sauvage Genentech USA12 00 12 15Closing remarks and Poster prize12 15 12 45 Packed lunch and Departure Practical information Registration Fees and Abstract Submission On site Registration Fees include admission conference materials COVID 19 safety measures meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Virtual Registration Fees include access to all of the talks livestreamed and on demand and facility to submit questions On site Academia 700On site PhD Student 600On site Industry 900Virtual Academia 175Virtual PhD Student 125Virtual Industry 225 NO visa support letters will be issued until payment of the registration fee is confirmed Accredited journalists may be eligible to register for a reduced press rate or in some cases for complimentary registration Registrants may be required to provide accreditation or equivalent proof of press membership after registration Please contact Maria Bacadare for more information Confirmation and payment Registration will be on a first come first served basis Your place can only be confirmed after payment of the registration fee If you are added to our waiting list please consider taking advantage of our offerings to participate virtually On site participants Types of payments accepted are international bank transfers and credit card payments Virtual participants We are only able to accept card payments In exceptional cases we can accept bank transfers Please contact events embl de for details Abstract submission Only registered participants attending the on site event are eligible to submit an abstract Abstracts will not be accepted from virtual participants After you have logged in and successfully registered you will receive an email asking you to submit your abstract Click on the link provided and enter your abstract in the text box provided Alternatively you can submit your abstract by clicking on the link on the confirmation page directly after registering The same login credentials are used for both processes Please note Title The title should not exceed 20 words Only the first word of the title should start with a capital letter and the rest of the title should be in lowercase Authors and Affiliations Please fill in the author s details as requested in the online form The compulsory details are First Name Last Name Organisation Name Affiliation or Company Country and Email Mark only one author as the role of First author and please don t forget to indicate who will be presenting The order of the authors will be listed as follows First Author Co First Author alphabetically if multiple co author s in the order added by the submitter Presentation Types When submitting your abstract you can apply for an oral or poster presentation A selection process will take place with the results announced 2 3 weeks after the abstract submission deadline Please check our FAQs pages for further information on how to submit an abstract Financial Assistance Financial assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of both registration fee waivers and travel grants Availability is limited to participants attending on site events in Heidelberg and will be indicated during the abstract or motivation letter submission process Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course or conference Travel grant The travel grant will cover the cost of travel airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Course EMBL Conference or EMBO EMBL Symposium from within Europe up to 1000 for participants travelling to an EMBL Course EMBL Conference or EMBO EMBL Symposium from outside Europe up to 500 for any participant travelling to an EMBO Practical Course or EMBO Workshop up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Practical Course or EMBO Workshop Registration fees are only covered for EMBO Practical Courses or EMBO WorkshopsThe organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Application You may apply for financial assistance when submitting your abstract for conferences In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Selection The scientific organisers will select the recipients of all financial assistance during the motivation letter or abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection is based on your current work or study location the reasons for needing financial support and the impact this event will have on your career Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details See our list of external funding opportunities and information on attending a conference as an event reporter For further information about financial assistance please refer to the FAQ page Accommodation and Shuttles Accommodation is not included in the conference registration fee As further changes in our events are possible due to COVID 19 you should book flights trains and hotels with flexible options and favourable cancellation conditions The hotels below have rooms on hold for participants until Wednesday 18 May 2022 in some cases at special rates Please quote the booking code EES22 07 and confirm the exact price of the room with the hotel directly Hotel AnlageHotel ibis HeidelbergPremier Inn Heidelberg CityHotel Bayrischer Hof ISG Hotel Staycity Aparthotel HeidelbergB B HotelLeonardo Hotel Heidelberg City CentreSteffi s Hostel HeidelbergExzellenz Hotel Boarding HouseHotel MonptiHotel Vier Jahreszeiten HeidelbergHotel Holl nder Hof Conference shuttle buses Conference shuttle buses are free of charge for participants and depart from designated bus stops near the hotels to EMBL and back mornings and evenings The bus stops for this conference are Download the bus schedule StayCity Hotel close to B B Hotel and Main Train Station Heidelberg HBF EMBL bus stop Premier Kurf rsten Anlage 23Leonardo Hotel Bergheimer Str Neckarm nzplatzPeterskircheISG Hotel View Conference shuttle bus stops and hotels in a larger map Please note that not every bus stop will be used for every event Further details Address EMBL Meyerhofstra e 1 69117 Heidelberg Germany For further information on getting to EMBL Heidelberg visit Public Transportation to the Venue For information about accommodation and local transportation please refer to the FAQ page Onsite Information Catering All meals and coffee breaks are included in the registration fee Our catering staff will prepare a wide variety of vegetarian meals meat and fish dishes soups pasta fresh fruit and vegetables as well as a variety of desserts Please wear your badge at all times when serving yourself No food or drinks are allowed in the auditorium Charging lockers There are lockers available next to the stairs leading down into the Auditorium You will find some of those equipped with sockets to charge your smartphone tablet etc Electricity and charging station In most places the electricity is 220 volts AC 50 cycles An adaptor and a plug that fits the German socket may be needed for your appliances laptop i e American Japanese etc A USB charging station for electronic devices is available at the registration desk EMBL merchandise EMBL Merchandise is available on Mon Thu 9 am 12 pm If you are interested in purchasing an EMBL souvenir products presented in the glass display in the registration area please ask at the registration desk for more information Health and safety notes Please read EMBL s COVID 19 terms and conditions for events Do not smoke in any EMBL building Eating and drinking is prohibited in the Auditorium and all laboratories Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required The first aid room is located next to the ATC Registration Desk room 10 205 Dial the Emergency number 222 from any EMBL internal phone only Where is the accident What happened How many injured Emergency number 06221 387 7821 from mobile phones Please report all accidents to the conference officer at the registration desk In case of fire Press the nearest fire alarm button or the Emergency number 222 from any internal phone A loud fire alarm will go off if an evacuation is required On hearing the alarm leave the building immediately following the escape route and fire wardens and head to one of the meeting pointsDo not use the lifts Beyond first aid Please remember to bring your own medication if needed to the conference Note that the next pharmacy is a 4 minute drive from the EMBL but for many medications you will be required to see a doctor to get a prescription Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg In any case the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary Internet Wi Fi is available everywhere on the premises no password required just log on to ATC Guest The eduroam network secure world wide roaming access service developed for the international research and education community is also available Lost and found Lost and Found are kept at the registration desk until the end of the conference Luggage There are lockers available on site to store your luggage which require a 2 EURO coin to operate There is another luggage room on level E0 which is free to use but remains unlocked during the conference Nursing room There is a nursing room available in the ATC Rooftop Lounge on level A29 Photography During the conference an EMBL Photographer may be taking photographs If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Printing We can help printing your boarding passes train ticket Please send it to events embl de and collect your print outs at the registration desk Room for prayer yoga and meditation There is a room for prayer mediation and yoga located on level E0 behind the Auditorium Please be respectful of other participants using the room Sightseeing A variety of activities in Heidelberg can be found on this website www heidelberg marketing com Travel to and from the venue During the event we provide conference shuttle busses to and from EMBL In addition there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time Information on the conference shuttle busses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page Useful German expressions EnglishGermanHelloHalloGoodbyeAuf WiedersehenGood morningGuten MorgenGood afternoonGuten TagGood eveningGuten AbendGood nightGute NachtI m sorryTut mir leidExcuse me Entschuldigen SieHow are you Wie geht s I m fine thanks And you Mir geht es gut danke und dir Ihnen What is your nameWie heisst du Wie heissen Sie My name isIch heisseDo you speak EnglishSprechen Sie Englisch I don t understandIch verstehe nichtPlease speak more slowlyK nnen Sie bitte langsamer sprechenThank youDanke sch nWhere is the toilet Wo ist die Toilette Please call me a taxiBitte rufen Sie mir ein TaxiHow do I get to Wie komme ich zum zur A beer two beers pleaseEin Bier zwei Bier bitteA glass of red white wine pleaseEin Glas Rot Weisswein bitteThe menu pleaseDie Speisekarte bitteIs there a local speciality Gibt es eine Spezialit t aus dieser Gegend I m VegetarianIch bin VegetarierIt was deliciousEs war hervorragendThe bill pleaseDie Rechnung bitteI have a headacheIch habe KopfschmerzenI have a sore throatIch habe HalsschmerzenMy stomach hurtsIch habe MagenschmerzenI m allergic toIch bin allergisch gegenI need a doctor who speaks EnglishGibt es einen Arzt der Englisch spricht Virtual Participation What s included Access to all the livestreamed talksVideo library of the recorded talks during and after the eventFacility to submit questions Please note that only on site participants are able to submit abstracts and participate in the poster sessions Event platform We are using an event platform for this conference More information about the platform will be shared ahead of the conference Guidelines Do not broadcast the conference to unregistered participants You are encouraged to tweet and post about the event Tweet unless the speaker specifically says otherwise but be mindful of unpublished data Please do not capture transmit or redistribute data presented at the meeting Additional information can be found in our Code of Conduct Health and well being It is important to stay healthy and move around especially when you are attending an event virtually We have put together a few coffee break stretches and yoga videos in the conference platform for you to enjoy during the event How to ask questions Please use the Q A function in the event platform If you have any other questions you can go to the Help Desk in the event platform Click on more on the top menu and click Help Desk Time zone The programme is planned based on the Europe Berlin time zone unless otherwise stated Please take your time zone into consideration when planning your attendance Additional Information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page COVID 19 Related Questions COVID 19 information for onsite events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Bronze sponsors Event sponsors Media partners Disease Models Mechanisms The Company of Biologists Journal EMBO Molecular Medicine an EMBO Press journal International Union of Biochemistry and Molecular Biology Molecular Oncology a FEBSPRESS journal Open Biology a Royal Society journal Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage About EMBO EMBL Symposia promote scientific communication and collaboration in the European research area They provide scientists with a platform to discuss and exchange ideas on forward looking topics and new developments in the life sciences Topics emphasise upcoming developments and the interdisciplinary nature of related fields Jointly funded and organised by EMBO and EMBL and complementary to their respective courses workshops and conference programmes the symposia promote scientific communication and collaboration All symposia are held in the EMBL Advanced Training Centre ATC in Heidelberg Germany or virtually...

Johanna Joyce, Daniel Klimmeck, Joan Massagué, Charles Swanton

EMBO | EMBL Symposium

EMBL Heidelberg, Virtual

15 June 2022

PRIDE database: Proteomics data submission, access and visualisation

Edit

June 15, 2022 15:302022WebinarVirtual

Description The webinar will provide an introduction to the PRIDE database and the proteomics data submission process This will also provide information about how to access public proteomics datasets including the PRIDE...

Deepti Jaiswal Kundu

Virtual

14 June 2022

Scope and vision of AlphaFold

Edit

June 14, 2022 13:302022WebinarVirtual

Description AlphaFold is an AI system developed by DeepMind that predicts protein 3D structure from its amino acid sequence It s been a year since the AlphaFold software and AlphaFold Protein Structure Database were made publicly available for users to explore and investigate their protein of interest We are running a webinar series to mark this occasion by highlighting the impact of AlphaFold on training and research in life sciences This is the first webinar of the series where the speaker will describe and discuss the scope and vision of AlphaFold Speakers Kathryn Tunyasuvunakool Machine learning models have the potential to become core tools in biology as recent progress in protein structure prediction illustrates In this webinar I gave an overview of AlphaFold how the system works how to obtain protein structure predictions and how to analyse them I then reviewed some ways in which the system has been built upon and discussed how to evaluate AlphaFold for a new application Randy Read Few areas of structural biology have been untouched by the recent dramatic increases in the power and accuracy of computational modelling of protein structure These changes have been wrought by the current version of AlphaFold with RoseTTAFold not far behind Experimental structural biology is still needed to resolve ambiguities in the predicted structures and to verify the details but the availability of high quality models is removing many of the bottlenecks in the experiments Even without an experimental structure the new models are sufficient to generate interesting hypotheses that can be tested experimentally such as assessing how variants associated with genetic disease actually cause disease Limitations in the models could potentially be addressed by adding explicit physics and chemistry to the pattern recognition used in the current algorithms and by actively exploiting even limited experimental observations Sergey Ovchinnikov I discussed the impact of AlphaFold on structural bioinformatics by highlighting a few large scale efforts and structure search tools developed to characterise the AlphaFold models...

Kathryn Tunyasuvunakool , Randy J Read, Sergey Ovchinnikov

Virtual

13 June - 17 June 2022

Summer school in bioinformatics

Edit

June 13, 2022 00:002022CourseEMBL-EBI

Description This course organised in association with Wellcome Connecting Science provides an introduction to the use of bioinformatics in biological research giving participants guidance for using bioinformatics in their work whilst also providing hands on training in tools and resources appropriate to their research Participants will initially be introduced to bioinformatics theory and practice including best practices for undertaking bioinformatics analysis data management and reproducibility To enable specific exploration of resources in their particular field of interest participants will be divided into focused groups to work on a project set by resource and data experts from EMBL EBI and external collaborating institutes These projects will end with a presentation from each group on the final day of the course to bring together learnings from all participants Participants will be required to review some pre recorded material prior to the start of the course and will have an opportunity to meet other trainees in an induction session to be held virtually in the week before the course take place Group projects A major element of this course is a group project where participants will be placed in small groups to work together on a challenge set by trainers from EMBL EBI and external institutes This allows people to explore the bioinformatics tools and resources available in their area of interest and apply them to a set problem providing participants with hands on experience relevant to their own research The group work will culminate in a presentation session involving all participants on the final day of the course giving an opportunity for wider discussion on the benefits and challenges of working with biological data Groups are mentored and supported by the trainers who set the initial challenge but the groups will be responsible for driving their projects forward with all members expected to take an active role Groups are pre organised before the course and all group members will be sent some short homework in preparation for their project work prior to the start of the course Basic outlines of the projects on offer this year are given below In your application you must indicate your first and second choice of project based on which you think would benefit your research most Not all projects may be offered and final decisions on which projects will be run during the course will be made based on the number of applicants per project Most of the projects cover mammalian data sets however in many cases the methods and approaches taught are transferable to data from various species Networks and pathways This project will cover typical bioinformatics analysis steps needed to put differentially expressed genes into a wider biological context You will start with gene expression data RNA seq to build an initial interaction network Next you will learn to combine public network datasets identify key regulators of biological pathways and explore biological function through network analysis You will get first hand experience in integration and co visualising with additional data and functional enrichment analysis All this helps to put the initial results into a previously known context and provide hypotheses for potential follow up experiments We will use Cytoscape Expression Atlas g Profiler StringDb among other tools We also may give a few R packages a try Project mentors Priit Adler University of Tartu Hedi Peterson University of Tartu Genome variation across human populations Natural variation between individuals or between different human populations is a result of genome mutations throughout evolutionary history Some mutations may become fixed because of their beneficial effect while most drift among individuals During this project you will investigate genomic variation between two separate human populations of European and Asian descent Using sequence data from a number of individuals from each population you will use a range of bioinformatics tools to discover variants that exist between them In the second section of the project you will attempt to analyse the functional consequences of the variants you have identified linking them to phenotypes Project mentors Baron Koylass EMBL EBI Modelling cell signalling pathways Curating models of biological processes is an effective training in computational systems biology where the curators gain an integrative knowledge of biological systems modelling and bioinformatics You will learn to encode and simulate ordinary differential equation models of signalling pathways from a recent publication using user friendly software such as COPASI even without extensive mathematical background You will learn to perform in silico experiments new predictions and develop hypotheses Furthermore you will learn how to annotate models and re use pre existing models from open repositories such as BioModels Project mentors Rahuman Sheriff EMBL EBI Interpreting functional information from large scale protein structure data This project will introduce you to the wealth of publicly available data in the Protein Data Bank PDB and give you the opportunity to investigate how large subsets of structure data can be used to analyse protein features and determine function In the project you will learn how to identify relevant protein structures collate and interpret functional information and implement this process programmatically Project mentors David Armstrong EMBL EBI Preeti Choudhary EMBL EBI Analysis of intercellular interactions in healthy and diseased states Ulcerative colitis is an inflammatory bowel disease The exact pathomechanism of the disease is unknown However the interactions between the intestinal immune cells and the intestinal epithelial cells play a crucial role during the development of the disease Single cell RNA seq measurements can help us understand these complex interactions The expression data combined with protein protein interaction databases can shed light on the connections between cells in diseased and healthy states During this project you will use a single cell RNA seq dataset to build interactions between the various cells The dataset contains pre processed cell type classified data of biopsies from healthy inflamed and non inflamed UC colonic biopsies The interactions between cells will be downloaded from the OmniPath database You will use Python Notebooks to build up the intercellular networks map the single cell RNA seq expression data and visualise them The intercellular networks between various cell types can then be compared by Cytoscape Project mentors Dezso Modos Quadram Institute Marton Olbei Earlham Institute...

EMBL-EBI Training team

EMBL-EBI

12 June - 17 June 2022

Humanized mice, personalized therapies and big data

Edit

Computer-assisted functional precision medicine in cancer

Edit

June 01, 2022 15:002022WebinarVirtual

Description Biological mechanisms provide a link between anti cancer compounds and therapy responses Insight to biological mechanisms is central for tomorrow s clinical decision support systems and personalised cancer therapy I will present the NTNU DrugLogics software that combines cancer signalling prior knowledge and data measurements to provide models that can predict therapy responses We combine in silico generated predictions with in vitro observations in the PRESORT project where patient derived cancer cultures are subjected to drugs and drug combinations predicted for the given patient to appreciate the efficacy for individual patients Together with Institut Curie Charit BSC Uppsala University and ProtAtOnce we test integrated computational and experimental pipelines on historic cohorts of patients treated at the molecular tumour boards at Institut Curie and Charit Current precision medicine trials including the nation wide trial IMPRESS Norway typically rely on individual and static biomarkers like DNA mutations for prediction of drug responses For future iterations of clinical decision support computer simulations taking in a number of data points and analyzed together combined with validation in patient derived tumour samples will be paramount About the speaker Dr smund Flobak works in clinical oncology and research at the St Olavs University hospital and at the Norwegian University of Science and Technology He is Project leader for the ERA PerMed project OncoLogics and for the RCN project PRESORT His work combines both experiments in the wet lab cell lines drug screening xenograft experiments and in the dry lab building logical models for drug combination response prediction development of a pipeline in Java for drug synergy studies Dr Flobak is the lead developer of the DrugLogics pipeline for drug synergy and resistance predictions The pipeline produces models tailored to single samples for drug synergy simulation and prediction...

Åsmund Flobak

Virtual

29 May - 3 June 2022

Whole transcriptome data analysis

Edit

Exploring human genetic variation

Edit

May 16, 2022 00:002022CourseVirtual

Description Do you want to understand more about genetic variation Are you aware of the resources available for finding viewing and exploring variant data Are you trying to link variant data to phenotypes This three day workshop will demonstrate resources and bioinformatics tools available at EMBL EBI and the Wellcome Sanger Institute that will aid understanding of human genetic variation Participants will learn via a mix of lectures trainer Q A sessions and hands on training Practical experience will be developed through group activities and trainer led exercises Live sessions will be delivered using Zoom with additional support and communication via Slack This course will take place over three non consecutive days 16 18 and 20 May 2022 Selected participants will be sent materials prior to the course These might include pre recorded talks and required reading or online training that will be essential to fully understand the course Participants will need to be available between the hours of 09 00 17 30 BST each day of the course Trainers will be available to assist answer questions and further explain the analysis during these times...

Jane Reynolds

Virtual

16 May - 20 May 2022

Advanced fluorescence imaging techniques

Edit

May 16, 2022 00:002022CourseVirtual

Description OverviewSpeakers and TrainersProgrammePractical InformationSponsors Overview EMBL is committed to sharing research advances and sustaining scientific interaction throughout the coronavirus pandemic We are delighted to announce that the course is going virtual and invite you to join us online Course Overview This practical course will cover advanced light microscopy techniques and participants will learn how to derive qualitative and quantitative insights on molecular mechanisms in cells and developing organisms Invited guest researchers together with experts from the EMBL and microscopy professionals will foster an intense information flow with a balance of lectures and practical workshops The focus of the course will be on the use of fluorescence microscopy to obtain information about protein localisation dynamics and functions at different spatial scales Audience This course is directed towards researchers in the life sciences with access to light microscopy equipment who have an immediate need to apply the techniques they will learn to solve biological problems at the cellular and molecular level in vivo Modules Resources The topics will include fluorescence microscopy techniques such as fast time lapse microscopy spinning disk and point scanning confocal microscopy light sheet microscopy of cleared samples photo manipulation as a tool multicolor single molecule localization microscopy SMLM with spectral demixing For the demanding applications we will cover the aspects of image analysis and possibilities of microscope automation The modules will cover all necessary knowledge and demonstrate tools to conduct similar pipelines at your home lab enabling you to answer emerging biological questions Course Format Information The entire course including hands on practicals will happen virtually All participants will attend lectures and live Q A sessions together each day between 13 00 and 16 00 times might vary slightly depending on the day Some lectures will happen live other lectures and tutorials will be prerecorded and provided to participants in advance Each prerecorded module will be associated with live Q A sessions to discuss with the speaker For practicals participants will be subdivided into four smaller groups Two groups will attend the practicals each day between 16 00 and 19 00 two other groups will attend the practicals from 9 00 to 12 00 Online practical sessions will run on four high end microscopes located at four different sites Practical providers will set up the audio visual equipment including cameras to explain and discuss the hardware with participants Then the screens of microscope computers will be shared with participants via Zoom In some practicals participants will get an opportunity to control the software remotely to configure new experiments and adjust experiment settings Learning Outcomes Participants will get an overview about advanced fluorescence imaging techniques This course is kindly supported by the EMBL Advanced Light Microscopy Facility This course is organised in cooperation with Olympus Speakers and Trainers Speakers and Trainers Benjamin Compans King s College London UK Joana Delgado Martins University of Zurich Switzerland Heiko Gaethje Olympus Europa SE Co KG Germany Manuel Gunkel EMBL Heidleberg Germany Aliaksandr Halavatyi EMBL Heidleberg Germany Mark Hink University of Amsterdam The Netherlands Debora Keller Olivier Abbelight France France Lam IBPS France Marko Lampe EMBL Heidelberg Germany Stefan Marawske Olympus Europa SE Co KG Germany Pedro Pereira ITQB Portugal Francesca Peri University of Zurich Switzerland Sanjana Singh EMBL Heidelberg Germany Stefan Terjung EMBL Heidelberg Germany Christian Tischer EMBL Heidelberg Germany Urs Ziegler University of Zurich Switzerland Joanna Zukowska Kasprzyk EMBL Heidelberg Germany Scientific Organisers Joana Delgado Martins University of Zurich Switzerland Manuel Gunkel EMBL Heidleberg Germany Aliaksandr Halavatyi EMBL Heidleberg Germany Debora Keller Olivier Abbelight France Stefan Marawske Olympus Europa SE Co KG Germany Irina Rakotoson PhaseView Olympus France Course Organisers Maryann Heck Course and Conference Officer EMBL Heidelberg Germany Yvonne Yeboah Training Laboratory Manager EMBL Heidelberg Germany Programme Got something to say EMBLFluorImaging The virtual course will start on Monday 9 May with an onboarding session and access to the pre recorded talks from invited speakers and trainers The course will continue on Monday 16 May with the regular programme Participants will be required to view the pre recorded talks 7 h prior to the main start of the course on Monday 16 May During the 5 day course duration full time attendance is required All times in the programme below are shown as the time in Europe Berlin To find out the equivalent time zone in your location enter Berlin the programme time and date along with your city into the Time Zone Converter This programme may be subject to change Day 0 Monday 9 May 2022 TimeSession13 00 16 00Onboarding and technical troubleshooting Day 1 Monday 16 May 2022 TimeSession12 30 13 00Welcome and course overview13 00 13 30Lecture Concepts in light microscopyUrs Ziegler University of Zurich Switzerland13 30 13 45Q A session Concepts in light microscopyUrs Ziegler University of Zurich Switzerland13 45 14 30Flash talk presentations by participants14 30 15 30Q A session based on material in pre recorded talks Concepts of image acquisition and processing Heiko Gaethje Olympus Europa SE Co KG15 30 16 00Break16 00 19 00Hands on microscopy practicals Multicolor single molecule localization microscopy with spectral demixingDebora Keller Olivier Abbelight France Group 3 Ultra thin light sheet microscope with automated multi scale imaging capabilities Irina Rakotoson PhaseView France Group 4 Day 2 Tuesday 17 May 2022 TimeSession09 00 12 00Hands on microscopy practicals Multicolor single molecule localization microscopy with spectral demixingDebora Keller Olivier Abbelight France Group 1 Ultra thin light sheet microscope with automated multi scale imaging capabilities Irina Rakotoson PhaseView France Group 2 12 00 13 00Break13 00 13 45Flash talk presentations by participants13 45 14 45Q A session based on material in pre recorded talks Principles and applications of photomanipulation techniques FRAP photoactivation and others and Adaptive feedback microscopy for high content imaging and beyond Aliaksandr Halavatyi EMBL Heidelberg Germany Manuel Gunkel EMBL Heidelberg Germany14 45 15 30Q A session based on material in pre recorded talks DIY super resolution Expanding biology above diffraction Pedro Matos Pereira ITQB Portugal 15 30 16 00Break16 00 19 00 Hands on microscopy practicals Live cell imagingJoana Delgado University of Zurich SwitzerlandUrs Ziegler University of Zurich Switzerland Group 3 Applying adaptive feedback microscopy for high throughput photoactivation of specific cell phenotypes Aliaksandr Halavatyi EMBL Heidelberg Germany Manuel Gunkel EMBL Heidelberg Germany Group 4 Day 3 Wednesday 18 May 2022 TimeSession09 00 12 00Hands on microscopy practicals Live cell imagingJoana Delgado University of Zurich SwitzerlandUrs Ziegler University of Zurich Switzerland Group 1 Applying adaptive feedback microscopy for high throughput photoactivation of specific cell phenotypes Aliaksandr Halavatyi EMBL Heidelberg Germany Manuel Gunkel EMBL Heidelberg Germany Group 2 12 00 13 00Break13 00 13 30Lecture The brain under surveillance Neural immune interactions in the development and repair of the CNS Francesca Peri University of Zurich Switzerland13 30 13 45 Q A session The brain under surveillance Neural immune interactions in the development and repair of the CNS Francesca Peri University of Zurich Switzerland13 45 14 15Lecture To diffraction limit and beyond using spectral demixing multicolor 3D dSTORM to study synapses organisationBenjamin Compans King s College London UK14 15 14 30Q A session To diffraction limit and beyond using spectral demixing multicolor 3D dSTORM to study synapses organisationBenjamin Compans King s College London UK14 30 15 00Lecture Light sheet imaging for live and cleared specimens France Lam IBPS France15 00 15 15 Q A session Light sheet imaging for live and cleared specimens France Lam IBPS France15 15 16 00Break16 00 19 00Hands on microscopy practicals Multicolor single molecule Localization Microscopy with Spectral DemixingDebora Keller Olivier Abbelight France Group 4 Ultra thin light sheet microscope with automated multi scale imaging capabilities Irina Rakotoson PhaseView France Group 3 Day 4 Thursday 19 May 2022 TimeSession09 00 12 00Hands on microscopy practicals Multicolor single molecule localization microscopy with spectral demixingDebora Keller Olivier Abbelight France Group 2 Ultra thin light sheet microscope with automated multi scale imaging capabilitiesIrina Rakotoson PhaseView France Group 1 12 00 13 00Break13 00 14 00Q A session based on material in pre recorded talks Measuring interactions and biosensors using FRETMark Hink University of Amsterdam The Netherlands14 00 14 30Lecture Single phenotype transcriptomics as a platform to identify networks regulating Golgi structureSanjana Singh EMBL Heidelberg Germany14 30 14 45Q A session Single phenotype transcriptomics as a platform to identify networks regulating Golgi structureSanjana Singh EMBL Heidelberg Germany14 45 15 45Social event Quiz Time15 45 16 00Break16 00 19 00Hands on microscopy practicals Live cell imagingJoana Delgado University of Zurich SwitzerlandUrs Ziegler University of Zurich Switzerland Group 4 Applying adaptive feedback microscopy for high throughput photoactivation of specific cell phenotypesAliaksandr Halavatyi EMBL Heidelberg Germany Manuel Gunkel EMBL Heidelberg Germany Group 3 Day 5 Friday 20 May 2022 TimeSession09 00 12 00Hands on microscopy practicals Live cell imagingJoana Delgado University of Zurich SwitzerlandUrs Ziegler University of Zurich Switzerland Group 2 Applying adaptive feedback microscopy for high throughput photoactivation of specific cell phenotypesAliaksandr Halavatyi EMBL Heidelberg Germany Manuel Gunkel EMBL Heidelberg Germany Group 1 12 00 13 00Break13 00 15 30Student presentationsPresentation of learning outcomes by participants15 30 16 00Wrap up and end of course Practical Information Registration Fees and Motivation Letter The course is limited to 16 participants For selection purposes please note that your application will not be considered without a letter of motivation Registration Registration Fees include admission and all course materials Academia 125PhD Student 125Industry 250 Confirmation and Payment The registration fee should be paid only after acceptance to the course The results will be announced approximately 2 3 weeks after the application deadline Motivation Letter Submission After you have logged in and successfully registered you will receive an email asking you to submit your motivation letter Click on the link provided and enter your motivation letter in the text box provided Alternatively you can submit your motivation letter by clicking on the link on the confirmation page directly after registering Instructions Include your relevant skills experience and qualifications showing why you would be suitable for the course Explain why you would like to attend including what you can contribute and how you think you will benefit from the course Please note The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised For more detailed information follow the instructions provided in our video on how to submit a course motivation letter Further Details For further information about registration and motivation letter submission please refer to the FAQ page Financial Assistance Financial Assistance Registration Fee Waivers All academic and student registrants are invited to apply for a registration fee waiver provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO The registration fee waiver covers the registration sum that you have paid to attend the meeting Conference participants are not required to pre pay the registration fee to be selected for a fee waiver for a virtual meeting If you have already paid the registration fee and are awarded a fee waiver it will be reimbursed after the meeting Course participants are required to pay the course fee in advance which will then be reimbursed after the recipient has attended the course Childcare Grants For participants and speakers with childcare responsibilities there is the possibility to apply for a grant provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO to offset childcare costs incurred when participating at a virtual event Eligible costs include fees for a babysitter or childcare facility or travel costs for a care giver Please note that priority will be given to early stage researchers Costs will be reimbursed after the meeting only once a reimbursement form and original receipts have been received Attendance at the event is required in order to be eligible to receive the reimbursement In order to apply for this grant you must be registered by the abstract submission deadline Boehringer Ingelheim Fonds Travel Grant Applies to selected courses only Availability will be indicated during the abstract or motivation letter submission process This grant covers costs related to your attendance to the course registration travel and accommodation costs The grant is restricted to PhD students and postdocs who conduct basic biomedical research Whether you are eligible to apply for a travel grant depends on when you received your university entrance qualification e g Abitur A Levels High School Diploma Final State Examination for PhD and MD students as well as graduates the university entrance qualification must not have been obtained more than 11 years ago at the time of the envisaged course for postdocs the university entrance qualification must not have been obtained more than 13 years ago at the time of the envisaged course Application Applications for financial assistance can be submitted via the submission portal for the submission of abstracts for conferences or the submission of motivation letters for courses by completing the Financial Assistance Application Section underneath the section for entering abstract motivation letter information The link to the portal can be found in the registration confirmation email that you will receive after registering for the conference or course For conferences if you are not submitting an abstract you can still apply for financial assistance in the submission portal Read the instructions on how to apply for financial assistance Note that priority will be given to those submitting an abstract to present at the conference In your application you will be asked to answer questions regarding your motivation for applying and for registration fee waivers the reasons why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application For some events applications for Childcare Grants will still be done by email Information about the grant will be sent out shortly after the abstract motivation letter deadline Please contact the event Conference Officer if you have any questions Selection The scientific organisers will select the recipients of registration fee waivers during the abstract selection process for conferences and the participant selection process for courses Results will be announced approximately 3 4 weeks before the event start date Selection results do not impact your admission to the meeting Registration fee waiver selection is based on your current work or study location your motivation for applying the reasons for needing financial support and the impact this event will have on your career Childcare grants are allocated based on career stage with priority given to early stage researchers Further details Check out this list of external funding opportunities or get more information on attending the conference as an event reporter For further information about financial assistance please refer to the FAQ page Technical Requirements Hardware During the course practicals we aim to broadcast the microscope software having many graphical elements Therefore following minimum hardware setup is recommended Minimum screen resolution Full HD 1920 1080 Use external screens Bigger screens 22 inch are beneficial Please use two screens if possible We will provide recommendations to participants how to set up VC software on two screens Headsets will improve audio quality and voice clarity Internet Requirements Client computer with fast and stable internet access for the live virtual sessions Minimum 50 mbit download and 10 mbit uploadPreferred 100 mbit download and upload at your host institute While using the software during the course please make sure you have nothing else using your bandwidth We recommend using a wired connection Additional Software The EMBL eCampus learning platform will be used to collaborate communicate and network with all of the course participants All participants will receive information on how to join shortly before the course We recommend using Chrome Safari or Mozilla Firefox browsers for eCampus Zoom will be used for the live talks and Q A sessions More information will be provided closer to the start of the course Other Information While using the software during the course please make sure you have nothing else using your bandwidth We recommend using a wired connection Additional Information Please find additional information including FAQs and terms and conditions on our Information for Participants page Sponsors This course is organised in cooperation with Olympus...

EMBL Course

Virtual

15 May - 19 May 2022

Microscopy data analysis: machine learning and the BioImage Archive

Edit

May 15, 2022 00:002022CourseVirtual

Description This course will introduce programmatic approaches used in the analysis of bioimage data via the BioImage Archive The content will explore a variety of data types including electron microscopy cell and tissue microscopy and miscellaneous or multi modal imaging data Participants will cover contemporary biological image analysis with an emphasis on machine learning and advanced image analysis Further instruction will be offered using applications such as ZeroCostDL4Mic ilastik ImJoy the BioImage Model Zoo and CellProfiler Virtual course Participants will learn via a mix of pre recorded lectures live presentations and trainer Q A sessions Practical experience will be developed through group activities and trainer led computational exercises Live sessions will be delivered using Zoom with additional support and asynchronous communication via Slack Pre recorded material may be provided before the course starts that participants will need to watch read or work through to gain the most out of the actual training event In the week before the course there will be a brief induction session Computational practicals will run on EMBL EBI s virtual training infrastructure meaning participants will not require access to a powerful computer or install complex software on their own machines Participants will need to be available between the hours of 09 00 17 30 BST each day of the course Trainers will be available to assist answer questions and provide further explanations during these times...

Juanita Riveros

Virtual

15 May - 18 May 2022

Mechanobiology in development and disease

Edit

May 15, 2022 00:002022ConferenceEMBL Heidelberg, Virtual

Description OverviewSpeakersProgrammePractical informationSponsorsAbout Overview This conference will take place at EMBL Heidelberg with the option to attend virtually Proof of COVID 19 vaccination or recovery is required for on site attendance Please see EMBL s COVID 19 safety policy for on site events Symposium overview Environmental mechanics impact the behaviour of cells which in turn modify their surroundings These bi directional cell tissue interactions have important consequences for gene expression cell fate and function and give rise to transient and permanent tissue modifications These processes are key for immunity and homeostasis but also play a role in pathological processes as they are critical for fibrosis inflammation and cancer metastasis This symposium will focus on the interplay of cells with their environment and will bring together clinicians cell biologists and material scientists interested in mechanobiology at the molecular cellular and tissue level to approach its role in human physiology and pathology from different perspectives and scales We will specifically discuss new technological approaches from the field of material sciences that enable the study of mechanobiology in vivo and in vitro keeping in mind their potential use in a more applied context Session topics Subcellular mechanicsCellular dynamicsTissue organisationMulti tissue interactionOrganismal morphogenesisMechanobiology towards the clinic Speakers Keynote speakers Lisa Manning Syracuse University USA Ed Munro University of Chicago USA Speakers Alexander Bershadsky National University of Singapore Singapore Anna Erzberger EMBL Heidelberg Germany Jacky G Goetz Inserm France Jochen Guck Max Planck Institute for the Science of Light Germany Edouard Hannezo Institute of Science and Technology Austria Austria Thomas Lecuit Coll ge de France and Institut de Biologie du D veloppement de Marseille France Rong Li National University of Singapore Singapore Jean L on Ma tre Institut Curie France Yanlan Mao University College London UK Ewa Paluch University of Cambridge UK J rg Renkawitz Ludwig Maximilian University of Munich Germany Pere Roca Cusachs Institute for Bioengineering of Catalonia and Universitat de Barcelona Spain Verena Ruprecht Centre for Genomic Regulation Barcelona Spain Amy Shyer The Rockefeller University USA Sebastian Streichan University of California Santa Barbara USA Pavel Tomancak Max Planck Institute of Molecular Cell Biology and Genetics Germany Danijela Matic Vignjevic Intitut Curie France Sara Wickstr m Max Planck Institute for Molecular Biomedicine and University of Helsinki Finland Scientific organisers Alba Diz Mu oz EMBL Heidelberg Germany Carl Philipp Heisenberg Institute of Science and Technology Austria Prisca Liberali Friedrich Miescher Institute for Biomedical Research Switzerland An ela ari Institute of Science and Technology Austria Austria Xavier Trepat Institute for Bioengineering of Catalonia Spain Conference organiser Nathalie Sneider EMBL Heidelberg Germany Programme Got something to say Tweet it EESMechanobiology Recorded talks will be accessible on demand for 2 weeks after the end of the event All times in the programme below are shown as the time in Europe Berlin Please find the poster listing here Day 1 Sunday 15 May 2022 TimeSpeaker11 30 13 00Registration and Lunch13 00 13 15Opening remarks by scientific organisers13 15 14 15Keynote Lecture 2 Dynamic coupling of signalling force generation and tissue remodeling during neural tube closureEd Munro University of Chicago USAAVAILABLE ON DEMAND AFTER LIVE STREAM 14 15 17 15Session 1Session chairs Alba Diz Mu oz and Carl Philipp Heisenberg14 15 14 40Transducing and shielding mechanical signals from integrins to the nucleusPere Roca Cusachs Institute for Bioengineering of Catalonia and Universitat de Barcelona SpainAVAILABLE ON DEMAND AFTER LIVE STREAM14 40 14 55Cytoplasmic forces functionally reorganize nuclear condensates in oocytesAdel Al Jord Coll ge de France FranceAVAILABLE ON DEMAND AFTER LIVE STREAM 14 55 15 40Coffee Break and Meet the speakerswith Ed Munro Pere Roca Cusachs and Adel Al Jord Nimesh Chahare15 40 16 05Physics of living matter From molecule to embryoSebastian Streichan University of California Santa Barbara USAAVAILABLE ON DEMAND AFTER LIVE STREAM16 05 16 20Synthetic epithelial morphogenesis through controlled stretching and bucklingNimesh Chahare Institute for Bioengineering of Catalonia Spain AVAILABLE ON DEMAND AFTER LIVE STREAM 16 20 16 45Mechanical cell cooperation promotes apoptotic cell clearance in the early embryoVerena Ruprecht Centre for Genomic Regulation SpainLIVE STREAM ONLY16 45 17 00Focal adhesion signalling mainly regulates the mechano responsive dynamics of Yes associated protein Windie Hoefs Francis Crick Institute UKAVAILABLE ON DEMAND AFTER LIVE STREAM 17 00 17 15Loss of nuclear volume under confinementAlice Williart Institut Curie FranceAVAILABLE ON DEMAND AFTER LIVE STREAM 17 15 18 15Pre dinner drinks18 15 19 45Dinner in the Canteen19 45 21 30After dinner drinks Day 2 Monday 16 May 2022 TimeSpeaker09 15 12 00Session 2Session chairs Rong Li and Xavier Trepat09 15 09 40High throughput mechanical phenotyping for in vitro diagnosticsJochen Guck Max Planck Institute for the Science of Light GermanyAVAILABLE ON DEMAND AFTER LIVE STREAM09 40 09 55Programming multicellular interactions and organization using synthetic cell adhesion moleculesAdam Stevens University of California San Francisco USA AVAILABLE ON DEMAND AFTER LIVE STREAM 09 55 10 10Topological attractors triggered by cell cell adhesion propertiesBernat Corominas Murtra University of Graz Austria AVAILABLE ON DEMAND AFTER LIVE STREAM 10 10 10 40Coffee Break and Meet the Speakerswith Verena Ruprecht Sebastian Streichan and Nimesh Chahare Bernat Corominas Murtra Windie Hoefs Raphael Reuten Alice Williart 10 40 11 05Dynamics and mechanics of cell shape during cellular state changesEwa Paluch University of Cambridge UKAVAILABLE ON DEMAND AFTER LIVE STREAM11 05 11 20Membrane to Cortex Attachment regulates cortical mechanicsLeanne Strauss EMBL Heidelberg GermanyAVAILABLE ON DEMAND AFTER LIVE STREAM 11 20 11 35Mechanochemical rules for membrane reshaping filamentsBillie Meadowcroft Institute of Science and Technology Austria AustriaAVAILABLE ON DEMAND AFTER LIVE STREAM 11 35 12 00Cephalic furrow in Drosophila what is it good for Pavel Tomancak Max Planck Institute of Molecular Cell Biology and Genetics GermanyAVAILABLE ON DEMAND AFTER LIVE STREAM12 00 13 30Lunch12 30 13 30Workshop Presentation of the ERC Funding SchemesModerator Nadia El Mjiyad European Research Council BelgiumPresenters Danijela Vignjevic Institue Curie FranceEdouard Hannezo Institute of Science and Technology Austria Austria LIVE STREAM ONLY13 30 16 25Session 3Session chairs Pere Roca Cusachs and An ela ari 13 30 13 55Deciphering the role of mechanics in a post molecular conception of vertebrate organogenesisAmy Shyer The Rockefeller University USA LIVE STREAM ONLY13 55 14 10Symmetry breaking in intestinal organoid formationCornelia Schwayer Friedrich Miescher Institute for Biomedical Research SwitzerlandLIVE STREAM ONLY 14 10 14 25Mitochondrial fission links ECM mechanotransduction to metabolic redox homeostasis and metastatic chemotherapy resistanceSirio Dupont University of Padua ItalyAVAILABLE ON DEMAND AFTER LIVE STREAM 14 25 14 50 Biochemical mechanical and geometrical information in morphogenesisThomas Lecuit Coll ge de France and Institut de Biologie du D veloppement de Marseille FranceAVAILABLE ON DEMAND AFTER LIVE STREAM 14 50 15 35Coffee Break and Meet the Speakerswith Thomas Lecuit Ewa Paluch Amy Shyer Pavel Tomancak and Sirio Dupont Billie Meadowcroft Cornelia Schwayer Leanne Strauss15 35 15 50A push pull mechanism of microtubule spectrin mechanics controls apical cell shape homeostasis during epithelial foldingYu Chiun Wang RIKEN Center for Biosystems Dynamics Research JapanAVAILABLE ON DEMAND AFTER LIVE STREAM 15 50 16 05Mechanical control of mammalian ovarian folliculogenesisChii Jou Chan National University of Singapore SingaporeAVAILABLE ON DEMAND AFTER LIVE STREAM 16 05 16 30Nuclear mechanotransduction regulation of cell fate and integritySara Wickstr m Max Planck Institute for Molecular Biomedicine and University of Helsinki FinlandLIVE STREAM ONLY16 30 17 00Flash talks 2 minutes 1 slide per talk 57 Esther Comellas 63 John Robert Davis 65 Lucas Dent 69 Julia Eckert 75 Mar a Garc a 91 C cile Jacques 95 Deqing Kong 113 Saranne J Mitchell 119 Fabrizio Andrea Pennacchio 127 Marta Sampietro 131 Jana Sipkova 145 Mehmet Can Ucar 147 Clementine Villeneuve 151 Qiutan Yang17 00 19 00Poster Session 1 odd with beer and snacksFree evening Day 3 Tuesday 17 May 2022 TimeSpeaker09 15 12 00Session 4Session chairs Verena Ruprecht and Xavier Trepat09 15 09 40The impact of chronic osmotic stress on mammalian cell growth and genome stabilityRong Li National University of Singapore SingaporeLIVE STREAM ONLY09 40 09 55Morphogen gradient orchestrates pattern preserving morphogenesis via motility driven un jammingDiana Pinheiro Institute of Science and Technology Austria AustriaLIVE STREAM ONLY 09 55 10 10Metastasis predisposition basement membrane mechanicsRaphael Reuten University of Freiburg GermanyAVAILABLE ON DEMAND AFTER LIVE STREAM 10 10 10 40Coffee Breakwith Sara Wickstr m Rong Li and Yu Chiun Wang Chii Jou Chan Diana Pinheiro Raphael Reuten10 40 11 05Mechanical and signalling interactions between microtubules and integrin adhesionsAlexander Bershadsky National University of Singapore SingaporeAVAILABLE ON DEMAND AFTER LIVE STREAM11 05 11 20Mechanical coupling of supracellular stress amplification and tissue fluidizationStig Ove B e Oslo University Hospital NorwayAVAILABLE ON DEMAND AFTER LIVE STREAM 11 20 11 35Plectin mediated cytoskeletal crosstalk controls tensional homeostasis and cell cohesion in epithelial sheetsMagdalena Prechova Institute of Molecular Genetics of the Czech Academy of Sciences Czech RepublicAVAILABLE ON DEMAND AFTER LIVE STREAM 11 35 12 00Mechanics of blastocyst morphogenesisJean Leon Maitre Institut Curie FranceAVAILABLE ON DEMAND AFTER LIVE STREAM12 00 13 30Lunch13 30 16 25Session 5Session chairs Thomas Lecuit and Prisca Liberali13 30 13 55Cancer associated fibroblasts form contractile capsules that actively compress cancer cells and modulate mechanotransductionDanijela Vignjevic Institut Curie FranceLIVE STREAM ONLY13 55 14 10Planar polarized myosin cables enable cell field positioning during Drosophila germband retractionSudeepa Nandi Tata Institute of Fundamental Research India LIVE STREAM ONLY 14 10 14 25Pulling or Pushing Revisiting the mechanics of C elegans gonad morphogenesisPriti Agarwal Tel Aviv University Israel LIVE STREAM ONLY 14 25 14 50 Mechanobiology of immune responsesJoerg Renkawitz Ludwig Maximilian University of Munich GermanyAVAILABLE ON DEMAND AFTER LIVE STREAM 14 50 15 35Coffee Break and Meet the Speakers with Alexander Bershadsky Joerg Renkawitz Danijela Vignjevic and Priti Agarwal Sudeepa Nandi Magdalena Prechova Stig Ove B e15 35 15 50Contact percolation promotes flocking migration and a pro inflammatory cytosolic DNA response in epithelial tissuesLeonardo Barzaghi IFOM the FIRC Institute of Molecular Oncology ItalyAVAILABLE ON DEMAND AFTER LIVE STREAM 15 50 16 05Piezo1 activates non canonical EGFR signallingCarlos Pardo Pastor King s College London UKAVAILABLE ON DEMAND AFTER LIVE STREAM 16 05 16 30Theoretical mechanobiology in multicellular systemsAnna Erzberger EMBL Heidelberg Germany AVAILABLE ON DEMAND AFTER LIVE STREAM16 30 17 00Flash talks 2 minutes 1 slide per talk 48 Shiri Avivi Kela 54 David Br ckner 62 Sarah D Annunzio 82 Hanna Maria H kkinen 92 Konstantinos Kalyviotis 102 Allison Lewis 116 Marianne Montemurro 128 Andreas Schoenit 140 Jakub Sumbal 142 St phanie Torrino 150 Harry Warner17 00 19 00Poster Session 2 even with beer and snacks19 00 22 00BBQ with live music from Lazy Fur Day 4 Wednesday 18 May 2022 TimeSpeaker09 15 12 45Session 6Session chairs Alba Diz Mu oz and Pavel Tomancak 09 15 09 40Multiscale interplay between cytoskeletal mechanics cellular fate and tissue geometryEdouard Hannezo Institute of Science and Technology Austria AustriaAVAILABLE ON DEMAND AFTER LIVE STREAM 09 40 09 55Morphodynamics of human brain organoid patterningAkanksha Jain ETH Z rich SwitzerlandAVAILABLE ON DEMAND AFTER LIVE STREAM 09 55 10 20Coping with Mechanical Stress Tissue dynamics during development and repairYanlan Mao University College London UKAVAILABLE ON DEMAND AFTER LIVE STREAM 10 20 10 50Coffee break and Meet the Speakerswith Anna Erzberger Edouard Hannezo Yanlan Mao and Leonardo Barzaghi Carlos Pardo Pastor Akanksha Jain Yekaterina Miroshinikova10 50 11 15Intravascular forces shape tumor metastasisJacky G Goetz Inserm FranceLIVE STREAM ONLY11 15 11 30Nulear deformation modulates stem cell fate by altering chromatin accessibility and gene expressionYekaterina Miroshinikova NIH USALIVE STREAM ONLY 11 30 11 45Spatial coordination between trophoblast migration and embryo growth determines peri implantation mouse developmentVladyslav Bondarenko EMBL Heidelberg Germany and Hubrecht Institute The NetherlandsAVAILABLE ON DEMAND AFTER LIVE STREAM 11 45 12 45Keynote lecture 2 Predicting onset and arrest of tissue remodeling in epithelial layersLisa Manning Syracuse University USAAVAILABLE ON DEMAND AFTER LIVE STREAM 12 45 13 00Closing Remarks and Poster Prize13 00 13 15Packed Lunch and Departure Practical information Registration Fees and Abstract Submission On site Registration Fees include admission conference materials COVID 19 safety measures meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Virtual Registration Fees include access to all of the talks livestreamed and on demand and facility to submit questions On site Academia 700On site PhD Student 600On site Industry 900Virtual Academia 175Virtual PhD Student 125Virtual Industry 225 NO visa support letters will be issued until payment of the registration fee is confirmed Accredited journalists may be eligible to register for a reduced press rate or in some cases for complimentary registration Registrants may be required to provide accreditation or equivalent proof of press membership after registration Please contact Nathalie Sneider for more information Confirmation and payment Registration will be on a first come first served basis Your place can only be confirmed after payment of the registration fee If you are added to our waiting list please consider taking advantage of our offerings to participate virtually On site participants For enquiries about late registration please contact Nathalie Sneider Types of payments accepted are international bank transfers and credit card payments Virtual participants We are only able to accept card payments In exceptional cases we can accept bank transfers Please contact events embl de for details Abstract submission The abstract submission deadline was on Monday 21 February For enquiries about submitting a late abstract for a poster presentation please contact Nathalie Sneider Financial Assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of both registration fee waivers and travel grants Availability is limited to participants attending on site events in Heidelberg and will be indicated during the abstract or motivation letter submission process Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration fee waiver The fee waiver will cover the registration sum that you have paid to attend the course or conference Travel grant The travel grant will cover the cost of travel airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Course EMBL Conference or EMBO EMBL Symposium from within Europe up to 1000 for participants travelling to an EMBL Course EMBL Conference or EMBO EMBL Symposium from outside Europe up to 500 for any participant travelling to an EMBO Practical Course or EMBO Workshop up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Practical Course or EMBO Workshop Registration fees are only covered for EMBO Practical Courses or EMBO WorkshopsThe organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Application You may apply for financial assistance when submitting your motivation letter for courses and abstract for conferences In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application For the Boehringer Ingelheim Fonds Travel Grant there is a pre application question during the motivation letter submission process and if selected you will be requested to complete a standard form and documentation consisting of your travel expense estimation Selection The scientific organisers will select the recipients of all financial assistance during the motivation letter or abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection is based on your current work or study location the reasons for needing financial support and the impact this event will have on your career Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details View our list of external funding opportunities and information on attending a conference as an event reporter For further information about financial assistance please refer to the FAQ page Accommodation and Shuttles Accommodation is not included in the conference registration fee As further changes in our events are possible due to COVID 19 you should book flights trains and hotels with flexible options and favourable cancellation conditions The hotels below have rooms on hold for participants until 14 April 2022 in some cases at special rates Please quote the booking code EES22 05 and confirm the exact price of the room with the hotel directly Hotel AnlageHotel ibis Heidelberg Staycity Aparthotel Heidelberg Hotel Bayrischer Hof ISG Hotel Steffi s Hostel Heidelberg B B HotelLeonardo Hotel Heidelberg City CentreHotel Vier Jahreszeiten Heidelberg Exzellenz Hotel Boarding HouseMeininger HeidelbergHotel Holl nder Hof Premier Inn Heidelberg City Conference Shuttle Buses Conference shuttle buses are free of charge for participants and depart from designated bus stops near the hotels to EMBL and back mornings and evenings Download the bus schedule The bus stops for this conference are Kurf rsten Anlage Opposite Main Train Station Premier Kurf rsten Anlage 23Leonardo Hotel Bergheimer Str NeckarmuenzplatzPeterskircheISG Hotel View Conference shuttle bus stops and hotels in a larger map Please note that not every bus stop will be used for every event Further details Address EMBL Meyerhofstra e 1 69117 Heidelberg Germany For further information on getting to EMBL Heidelberg visit Public Transportation to the Venue For information about accommodation and local transportation please refer to the FAQ page Virtual Participation What s included Access to all the livestreamed talksVideo library of the recorded talks during and after the eventFacility to submit questions Please note that only on site participants are able to submit abstracts and participate in the poster sessions Event platform We are using an event platform for this conference More information about the platform will be shared ahead of the conference Guidelines Do not broadcast the conference to unregistered participants You are encouraged to tweet and post about the event Tweet unless the speaker specifically says otherwise but be mindful of unpublished data Please do not capture transmit or redistribute data presented at the meeting Additional information can be found in our Code of Conduct Health and well being It is important to stay healthy and move around especially when you are attending an event virtually We have put together a few coffee break stretches and yoga videos in the conference platform for you to enjoy during the event How to ask questions Please use the Q A function in the event platform If you have any other questions you can go to the Help Desk in the event platform Click on more on the top menu and click Help Desk Time zone The programme is planned based on the Europe Berlin time zone unless otherwise stated Please take your time zone into consideration when planning your attendance Additional Information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page COVID 19 Related Questions COVID 19 information for onsite events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Bronze sponsors Media partners Development a The Company of Biologists journal Disease Models Mechanisms The Company of Biologists Journal Journal of Cell Science a The Company of Biologists journal EMBO reports an EMBO Press journal Open Biology a Royal Society journal Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other events or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage About EMBO EMBL Symposia promote scientific communication and collaboration in the European research area They provide scientists with a platform to discuss and exchange ideas on forward looking topics and new developments in the life sciences Topics emphasise upcoming developments and the interdisciplinary nature of related fields Jointly funded and organised by EMBO and EMBL and complementary to their respective courses workshops and conference programmes the symposia promote scientific communication and collaboration All symposia are held in the EMBL Advanced Training Centre ATC in Heidelberg Germany or virtually...

Alba Diz-Muñoz, Carl-Philipp Heisenberg, Prisca Liberali, Anđela Šarić, Xavier Trepat

EMBO | EMBL Symposium

EMBL Heidelberg, Virtual

11 May 2022

Edit

May 09, 2022 00:002022ConferenceEMBL Barcelona

Description OverviewSpeakersProgrammePractical InformationSponsors Overview This conference will take place at EMBL Barcelona Proof of COVID 19 vaccination recovery or negative test is required for on site attendance Please see EMBL s COVID 19 safety policy for on site events Conference Overview Blood vessels arise during early development and are essential for the formation and maintenance of larger tissues and organs The vascular system regulates exchange of oxygen nutrients toxins and immune cells the dysfunction of which can cause pathologies as well as be consequent to the later stages of disease Classical mouse models genetics and histology have provided significant knowledge to the field of vascular biology in addition to recent advancements in diverse imaging modalities single cell approaches and computational modelling Yet there remain many open questions surrounding human vascular development and disease Blood vessels present numerous research challenges due to their complex 3D geometry and a strong coupling between biology and mechanics Cutting edge microfluidic and tissue engineering technologies offer a higher degree of control over design system perturbations and characterisation These advances also hold great promise for the development of relevant preclinical models personalized and regenerative medicine With the emergence and consolidation of these technologies we bring together vascular biologists and bioengineering researchers from across Europe and beyond who are pioneering these new tools towards understanding vascular biology in health and disease Session Topics Developmental vascular biologyLymphaticsSignalling and angiogenesisMechano vascular biologyVascular infection and integrityVascular oncologyAging in vascular biologyCardiovascular development and disease Speakers Keynote Speakers Christopher Chen Boston University USA Cancelled Karen Hirschi University of Virginia USA Roger Kamm Massachusetts Institute of Technology USA Speakers Amparo Acker Palmer Goethe University Frankfurt Germany Ralf Adams Max Planck Institute for Molecular Biomedicine Germany Heinz Georg Belting University of Basel Switzerland Katie Bentley The Francis Crick Institute UK Maria Bernabeu EMBL Barcelona Spain Anna Bigas Hospital del Mar Medical Research Institute Spain Rong Fan Yale University USA Mercedes Fernandez IDIBAPS Biomedical Research Institute Spain Cl udio Franco Institute of Molecular Medicine Portugal Maike Frye University Medical Center Hamburg Germany Virtual Speaker Mark Gillrie University of Calgary Canada Samy Gobaa Institut Pasteur France Mariona Graupera Josep Carreras Leukaemia Research Institute Spain Kristina Haase EMBL Barcelona Spain Shane Herbert The University of Manchester UK Christopher Hughes University of California Irvine USA Stephan Huveneers Amsterdam UMC The Netherlands Jessie Jeon Korea Advanced Institute of Science and Technology South Korea Virtual Speaker Michael Mak Yale University USA Milica Radisic University of Toronto Canada Jeroen Rouwkema University of Twente The Netherlands Pipsa Saharinen University of Helsinki Finland Cecilia Sahlgren bo Akademi University Finland Didier Stainier Max Planck Institute for Heart and Lung Research Germany Michael Vanlandewijck Uppsala University Sweden Karina Yaniv Weizmann Institute of Science Israel Ryuji Yokokawa Kyoto University Japan Ying Zheng University of Washington USA Virtual Speaker Scientific Organisers Katie Bentley The Francis Crick Institute UK Maria Bernabeu EMBL Barcelona Spain Kristina Haase EMBL Barcelona Spain Milica Radisic University of Toronto Canada Conference Organisers Raili Pall EMBL Heidelberg Germany Aline Cecilie Schnieder EMBL Heidelberg Germany Silvia Autet Balcells EMBL Barcelona Spain Programme Got something to say Tweet it EMBOBuildNetworks All times in the programme below are shown as the time in Europe Berlin Day 1 Monday 9 May 2022 TimeSpeaker09 00 10 00Registration and coffeeSession I New developments in vascular biologySession chair Kristina Haase EMBL Barcelona Spain 10 00 10 15Opening RemarksKristina Haase EMBL Barcelona Spain10 15 11 00KEYNOTE TALKA self assembled model of the blood brain barrierRoger Kamm Massachusetts Institute of Technology USA11 00 11 45KEYNOTE TALKRegulation of Endothelial Cell SpecializationKaren Hirschi University of Virginia USA11 45 12 00Tour of EMBL Barcelona selected participants only 11 45 13 15Lunch Meet the SpeakersSession II Developmental vascular biologySession chairs Maria Bernabeu EMBL Barcelona Spain Shane Herbert The University of Manchester UK 13 15 13 45Junctional dynamics during angiogenic sprouting anastomosis and lumen formationHeinz Georg Belting University of Basel Switzerland13 45 14 15Methods for defining vascular cell types in health and diseaseMichael Vanlandewijck Uppsala University Sweden14 15 14 30The interplay between Sox9 and endothelial cells in vasculature formationGiovanni Dalmasso EMBL Barcelona Spain14 30 15 00From hemogenic endothelium to hematopoietic stem cells dissecting Notch functionsAnna Bigas Hospital del Mar Medical Research Institute Spain15 00 15 30Coffee break15 30 16 00Molecular mechanisms coordinating endothelial cell behaviourClaudio Franco Institute of Molecular Medicine Portugal16 00 16 15Mechanisms in vascular remodelling and vessel size control going against the flowHolger Gerhardt Max Delbr ck Center for Molecular Medicinein the Helmholtz Association Germany16 15 16 45New organ on chip approaches for angiogenesis and vasculature developmentSamy Gobaa Institut Pasteur France16 45 17 00Short break Session III Emerging topics LymphaticsSession chair Michael Mak Yale University USA17 00 17 30Selective regulators of lymphatic endothelial junctionsMaike Frye University Medical Center Hamburg Germany Virtual Speaker 17 30 17 45Modular HA hydrogels to control lymphatic networks for tissue engineering applicationsLaura Alderfer University of Notre Dame USA17 45 18 15Tubing the vertebrate s body mechanisms of blood and lymphatic vessel formationKarina Yaniv Weizmann Institute of Science Israel18 15 18 45Flash talks by selected participants Akinola Akinbote EMBL Barcelona Spain poster 33 Nensi Alivodej Max Planck Institute for Brain Researchand Goethe University Frankfurt Germany poster 36 Camille Comp re Coll ge de France France poster 56 Lisa Frank Goethe University Frankfurt Germany poster 63 Idris Salmon KU Leuven Belgium poster 113 18 45 20 30Poster session 1 ODD numbers with drinks snacks Day 2 Tuesday 10 May 2022 TimeSpeaker08 30 09 00RegistrationSession I Mechano vascular biologySession chairs Milica Radisic University of Toronto Canada Stephan Huveneers Amsterdam UMC The Netherlands09 00 09 30Building perfusable microvascular modelsfor tissue regeneration and disease modelingYing Zheng University of Washington USA Virtual Speaker 09 30 09 45Dynamics of the endothelial cadhesome under blood flowEmir Bora Akmeric Max Delbr ck Center for Molecular Medicine in the Helmholtz Association Germany09 45 10 15Junctional mechanotransduction in angiogenesisStephan Huvaneers Amsterdam UMC The Netherlands10 15 10 30The junctional mechanosensor Amotl2 regulates endothelial Yap through modulation of DNA methylationAarren Mannion Karolinksa Institute Sweden10 30 11 00Coffee break11 00 11 30Dynamic and Non Elastic Interactions in the Extracellular MatrixMichael Mak Yale University USA11 30 11 45Human brain microvascular endothelial cell remodeling in response to circumferential stretch in a microvessel on chipClara Ram n Lozano cole Polytechnique France11 45 12 15Engineering the mechanical environment to tune vascularcell and tissue developmentJeroen Rouwkema University of Twente The Netherlands12 15 12 30Blood flow oscillations are triggered by irregular vascular networks a microscale mechanism for cycling hypoxia in tumours Yaron Ben Ami University of Oxford UK12 30 13 00Perfusable on chip vascular network for mechanobiologyand organogenesis applicationsRyuji Yokokawa Kyoto University Japan13 00 13 15Tour of EMBL Barcelona selected participants only 13 00 14 00Lunch Meet the SpeakersSession II Signalling angiogenesisSession chair Claudio Franco Institute of Molecular Medicine Portugal14 00 14 30Temporal adaptation of vascular network topologyKatie Bentley The Francis Crick Institute UK14 30 15 00Mechanosensitive Notch signaling regulates structural homeostasis of the arterial wallCecilia Sahlgren bo Akademi University Finland15 00 15 15Inverting angiogenesis with interstitial flow and chemokine matrix binding affinityGuillermo Vilanova Polytechnic University of Catalonia Spain15 15 15 45Deciphering angiogenic cues encoded in cell shapeShane Herbert The University of Manchester UK15 45 16 15PIK3CA mutations in endothelial cells the emerge ofan oncoprotein beyond cancerMariona Graupera Josep Carreras LeukaemiaResearch Institute Spain16 15 16 45Coffee break Session III Emerging topics Vascular infection integritySession chair James Sharpe EMBL Barcelona Spain16 45 17 15Regulation of vascular integrity via adhesionreceptor signallingPipsa Saharinien University of Helsinki Finland17 15 17 30Vasculature on a chip platform with innate immunity enables identification Of Angiopoietin 1 peptide as a therapeutic for SARS CoV 2 induced inflammationRick Lu University of Toronto Canada17 30 18 00Recreating cerebral malaria with in vitro 3Dbrain microvascular modelsMaria Bernabeu EMBL Barcelona Spain postponedto Wednesday 11 May 2022 18 00 18 15Engineered 3D vessels on chip to model inflammatory responses using hiPSC derived vascular cells and monocytesMerve Bulut Leiden University Medical Center the Netherlands18 15 18 45Flash talks by selected participants Irene Aspalter The Francis Crick Institute UK poster 40 Hannah Fleckenstein EMBL Barcelona Spain poster 62 Jacky Goetz The Institute of Hematology andImmunology France poster 68 Claire Leclech cole Polytechnique France poster 86 L a Pinon Institut Pasteur France poster 108 18 45Group photos18 45 20 30Poster session 2 EVEN numbers with drinks snacks21 00 23 00Conference dinner registered participants only Day 3 Wednesday 11 May 2022 TimeSpeaker08 45 09 15Registration09 15 09 45Recreating cerebral malaria with in vitro 3Dbrain microvascular modelsMaria Bernabeu EMBL Barcelona Spain Session I Vascular oncologySession chairs Katie Bentley The Francis Crick Institute UK Kristina Haase EMBL Barcelona Spain09 45 10 15Modeling the Perivascular Niche in Human Brain TumorRong Fan Yale University USA10 15 10 30ccRCC spheroids reveal a specific tumor vasculature resistant to anti angiogenic treatmentNo mie Brassard Coll ge de France France10 30 11 00Complement from Tumour Extracellular Vesicles Regulates Metastasis in an on Chip Human Pre Metastatic NicheMark Gillrie University of Calgary Canada11 00 11 30Coffee break11 30 12 00Investigation of cancer microenvironment withperfusable vasculature in microfluidic systemJessie Jeon Korea Advanced Institute of Scienceand Technology South Korea Virtual Speaker 12 00 12 30Patient derived vascularized colon cancer tumor on a chip recapitulates patient drug responsesChristopher Hughes University of California Irvine USA12 30 12 45Tour of EMBL Barcelona selected participants only 12 30 13 30Lunch Meet the SpeakersSession II Ageing in vascular bioSession chair Holger Gerhardt Max Delbr ck Center for Molecular Medicine in the Helmholtz Association Germany13 30 14 00Role of the vasculature in bone growth homeostasis regeneration and agingRalf Adams Max Planck Institute for Molecular Biomedicine Germany14 00 14 30Neurovascular interactions during CNS developmentAmparo Acker Palmer Goethe University Frankfurt Germany14 30 15 00Dysregulation of angiogenesis in chronic liver diseaseMercedes Fernandez IDIBAPS Biomedical ResearchInstitute Spain15 00 15 30Genetic robustnessDidier Stainier Max Planck Institute for Heartand Lung Research Germany15 30 16 00Coffee breakSession III Cardiovascular development diseaseSession chair Karina Yaniv Weizmann Institute of Science Israel16 00 16 15Changes in extracellular matrix in failing human non ischemic and ischemic hearts with mechanical unloadingYimu Zhao University of Toronto Canada16 15 16 45Heart on a chip models of healthy and diseased myocardiumMilica Radisic University of Toronto Canada16 45 17 15Tissue specific human vascularized models to study fibrosis and other cardiac diseasesKristina Haase EMBL Barcelona Spain17 15 17 30Awards Final remarksMaria Bernabeu EMBL Barcelona Spain17 30 18 00Farewell Cava Practical Information Registration Fees and Abstract Submission Registration Fees include admission conference materials COVID 19 safety measures meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Academia 425PhD Student 325Industry 725 NO visa support letters will be issued until payment of the registration fee is confirmed Accredited journalists may be eligible to register for a reduced press rate or in some cases for complimentary registration Registrants may be required to provide accreditation or equivalent proof of press membership after registration Please contact Raili Pall for more information Confirmation and Payment Registration will be on a first come first served basis Your place can only be confirmed after payment of the registration fee Types of payments accepted are international bank transfers and credit card payments Abstract submission After you have logged in and successfully registered you will receive an email asking you to submit your abstract Click on the link provided and enter your abstract in the text box provided Alternatively you can submit your abstract by clicking on the link on the confirmation page directly after registering The same login credentials are used for both processes Please note Title The title should not exceed 20 words Only the first word of the title should start with a capital letter and the rest of the title should be in lowercase Authors and Affiliations Please fill in the author s details as requested in the online form The compulsory details are First Name Last Name Organisation Name Affiliation or Company Country and Email Mark only one author as the role of First author and please don t forget to indicate who will be presenting The order of the authors will be listed as follows First Author Co First Author alphabetically if multiple co author s in the order added by the submitter Presentation Types When submitting your abstract you can apply for an oral or poster presentation A selection process will take place with the results announced 2 3 weeks after the abstract submission deadline Please check our FAQs pages for further information on how to submit an abstract Financial Assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of both registration fee waivers and travel grants Availability is limited to participants attending on site event and will be indicated during the abstract or motivation letter submission process Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration Fee Waiver The fee waiver will cover the registration sum that you have paid to attend the course or conference Travel Grant The travel grant will cover the cost of travel airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Course EMBL Conference or EMBO EMBL Symposium from within Europe up to 1000 for participants travelling to an EMBL Course EMBL Conference or EMBO EMBL Symposium from outside Europe up to 500 for any participant travelling to an EMBO Practical Course or EMBO Workshop up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Practical Course or EMBO Workshop Registration fees are only covered for EMBO Practical Courses or EMBO WorkshopsThe organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Childcare Grant EMBO Practical Courses and Workshops only For EMBO Practical Course or EMBO Workshop participants with children there is the possibility to apply for a childcare grant to offset child care costs incurred by participants or speakers when participating at a course or conference Eligible costs include fees for a baby sitter or child care facility travel costs for a care giver or travel costs for taking the child to the meeting etc Please note that priority will be given to early stage researchers A maximum amount of 500 EUR can be awarded per participant applying for an EMBO Childcare Grant In order to apply for this grant for EMBO Workshops you must be registered by the abstract submission deadline Application You may apply for financial assistance when submitting your motivation letter for courses and abstract for conferences In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Selection The scientific organisers will select the recipients of all financial assistance during the motivation letter or abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection is based on your current work or study location the reasons for needing financial support and the impact this event will have on your career Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details View our list of external funding opportunities and information on attending a conference as an event reporter For further information about financial assistance please refer to the FAQ page Venue EMBL Barcelona is located at the Barcelona Biomedical Research Park PRBB The PRBB is located on Barceloneta seafront between Hospital del Mar and the Arts Hotel in the Olympic Port of Barcelona Address Barcelona Biomedical Research Park C Doctor Aiguader 88 08003 Barcelona The conference is taking place in the PRBB auditorium It is located on a raised level in the heart of the PRBB building overlooking the sea with independent access from the rest of the building Access to the Auditorium will be by the stairs located at the entrance of the inner square of the building For people with limited mobility the access through lifts up the 1st floor can be used While on campus please wear your conference badge at all times for security purposes PRBB EMBL Barcelona PhotoCredit Jordi Casa as EMBL Accommodation Accommodation is not included in the conference registration fee Below is a list of hotels that are located near the conference venue Please note that a city tax per person per night for the stay needs to be paid whether you book in a hotel or through Airbnb Hotel NameAddressBookingsH10 MarinaAvinguda del Bogatell 64 68 Olympic Village 08005 Barcelona map website Tel 34 933 09 79 17 corporate hmb h10hotels com grupos hmb h10hotels comH10 Port VellPas de Sota Muralla 9 08003 Barcelona map website Tel 34 933 10 30 65 reservas hpv h10hotels comHotel SB Icaria Av d Ic ria 195 08005 Barcelona map website Tel 34 932 21 82 00 reservations icaria sbhotels esHotel Ibis Styles Carrer de Llull 71 08005 Hb004742 Barcelona map website Tel 34 934 83 37 48 H9663 accor comRESA campus del Mar ResidenciaPg Salvat Papasseit 4 08003 Barcelona map website Tel 34 933 90 40 00 campusdelmar resa esRESA La Ciutadella ResidenciaPasseig Pujades 33 37 08018 Barcelona map website Tel 34 933 94 32 00 ciutadella resa es Onsite Information Catering Lunches and coffee breaks are included in the registration fee The lunch buffets and coffee breaks will be set up in front of the Auditorium Snacks will be served on the first evening of the workshop during the Welcome reception PRBB terrace as well as during the poster sessions groundfloor beneath the Auditorium Dinners are at the participants own expense Please wear your badge at all times when serving yourself No food or drinks are allowed in the PRBB auditorium Electricity and charging station The mains voltage in Barcelona is 230 volts AC The flat European standard and the Schuko plug CEE 7 7 fit into the Spanish sockets Most Europeans do not need to buy an adapter plug for Spain Please note that there are no power outlets in the auditorium You can recharge your electronic devices at the reception area We kindly ask you to bring your own charger cables The charging station will be left unattended Health and safety notes Please read Barcelona s COVID 19 terms and conditions for events Smoking is prohibited in all PRBB facilitiesEating and drinking is prohibited in the Auditorium Do not enter any restricted areas or the laboratories unless authorised to do so Do not enter any restricted areas or the laboratories unless instructed to do so If first aid is required Assist the casualty and provide first aid if trained to do so Take to Hospital del Mar Pg Maritim Barceloneta 23 31 ORDial the emergency number 1020 from any internal phone ORDial 112Please report all accidents to the Conference Officer at the Registration Desk In case of fire Press the nearest fire alarm button or dial the emergency number 1020 from any internal phone There will be a loudspeaker announcement in Catalan Spanish English if an evacuation is required On hearing the evacuation message leave the building promptly following the escape route and exit signs and proceed to the meeting point Punto the reunion on Passeig Maritim Barceloneta next to the sea side Beyond first aid Please remember to bring your own medication if needed to the conference Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor Internet It is easy to access the internet via a wireless connection in any area of the building When connecting a mobile device the operating system automatically recognises the network PRBB The passport for this network is darwin1809 The PRBB also participates in the Eduroam project which aims to allow network access for visitors from academic institutions associated with Eduroam Access to the service is always delivered with the same credentials as in the home institution Lost and found Lost and Found items are kept at Registration and will be stored at the EMBL Barcelona reception for a short whileafter the EMBO workshop Luggage There are no lockers available on site to store your belongings It is highly recommended to leave any valuables in your accommodation An unguarded wardrobe area is behind the registration desk You may use this wardrobe at the last day of the Workshop to store your luggage The venue is directly located at the beachside Be aware of your surroundings and belongings when leaving the building Phone numbers In case of emergency contact Security on the ground floor Ext 1020 0034933160020 Reception Ext 1000 or 0034933160000 Below are the most important emergency service phone numbers for Barcelona Fire service 080 Medical emergencies 061 Police Mossos d Esquadra 088 The Mossos d Esquadra are Catalonia s autonomous community police force They are responsible for crime investigations crime prevention and assistance at accident scenes Gu rdia Urbana 092 The Gu rdia Urbana are responsible for public order by patrollling the roads and streets They also look after traffic safety and control The Guardia Urbana are also the first point of call for everyday situations such as neighbourhood disputes like noise etc All general emergencies 112 If you become ill during the event please notify the Conference Officer s immediately Photography During the conference an EMBL Photographer may be taking photographs If you would not like to appear in these please inform the photographer or a member of the Course and Conference Office Pickpockets It is highly recommended to leave any valuables in your accommodation The venue is located at the beachside which is a very busy area Be aware of your surroundings and belongings when leaving the building Sightseeing A variety of activities in Barcelona can be found in this website https www barcelona tourist guide com Time Spain operates on Central European time CET which means that the country is 6 hours ahead of eastern standard time EST in the United States and 1 hour ahead of Greenwich mean time GMT Travel to and from the venue Our EMBO Workshop partner hotel the H10 Marina is a 15 minutes walk to the venue If you prefer you can also take the bus The next bus stop is in 6 minutes walking distance to the hotel Line V27 is departing from Av Ic ria Joan Mir to Pg Mar tim Hospital del Mar From there it is another 3 minute walk Additionally a taxi stand is located just outside the hotel main entrance Hotel address Avinguda del Bogatell 64 68 Olympic Village 08005 Barcelona Useful Spanish expressions EnglishSpanishHelloHolaGood morningGood afternoonGood eveningGood nightBuenos d asBuenas tardesBuenas nochesBuenas nochesI m sorryLo siento PerdonaExcuse me Perd neme How are you C mo est s I m fine thanks And you Estoy bien gracias Y usted What is your nameC mo te llamasMy name isMe llamoDo you speak EnglishHabla usted Ingl sI don t understandNo entiendoPlease speak more slowlyPor favor hable m s despacioThank youGraciasWhere is the toilet D nde est el servicio Please call me a taxiPuedes avisar llamar un taxi por favor How do I get to Como llego a A beer two beers please Una cerveza dos cervezas por favor A glass of red white wine pleaseUn vaso de vino tinto blanco por favor The menu pleaseEl men por favorIs there a local speciality Hay alguna especialidad local I m VegetarianSoy vegetarianoaIt was deliciousEstaba deliciosoThe bill pleaseLa cuenta por favorI have a headacheMe duele la cabezaI have a sore throatTengo dolor de gargantaMy stomach hurtsMe duele el est magoI m allergic toSoy al rgico aI need a doctor who speaks EnglishNecesito un m dico que hable ingl s Transport Information Getting to Barcelona By Plane Barcelona El Prat airport is located in El Prat de Llobregat just 12 km South West of the Barcelona city centre It has two passenger terminals Terminal 1 T1 and Terminal 2 T2 The airport has allocated airlines to terminals regardless of the destination of the flight Airport Transfers to the city centre The Aerob s is an express bus service that connects the Barcelona El Prat airport with the city centre Pla a Catalunya in 35 minutes You can take the Aerob s outside Terminal 1 A1 and Terminal 2 A2 This service runs every day of the year with departures between 5 and 15 minutes From the city centre you can take the metro or a bus to move around Barcelona The train service R2 line runs approximately every 30 minutes to and from Barcelona airport to the city centre The journey takes 25 minutes The train service operates from Terminal 2 T2 To get from T2 to T1 use the shuttle bus service Bus transit T1 T2 If you travel from the airport to the city centre you can get off at Barcelona Sants Passeig de Gr cia or Clot which are serviced by metro stops You can also take the metro line L9 orange from the airport It departs at Terminal 1 and connects at stations Torrassa L1 and L10 Sud Collblanc L5 and L10 Sud with metros to the city centre You will find a taxi rank outside any of the main terminal exits Look for the sign pointing to the nearest taxi rank All official Barcelona taxis are black and yellow and are required to charge you only the value on the taximeter plus any surcharge e g luggage or night The rates and surcharges are displayed inside the cab In Barcelona a taxi may be either ordered by phone found at authorised taxi rank or flagged down in the street Getting to Barcelona By train Barcelona Sants is the main train station for national and international arrivals and departures in Barcelona It is situated in pla a dels Pa sos Catalanes Barcelona National and regional trains also depart from Fran a station It is located at avinguda Marqu s de l Argentera s n Barcelona Spanish Railways RENFE Public Transport in Barcelona Metro and tram The metro network of Barcelona is very good and the trains are frequent and quick You do not have to worry about timetables Almost all attractions are within walking distance of a metro or tram station When there are no subways the gap can be filled by tram You can find the operating hours of the metro and tram here Buses The operating times of the buses are different for each line You will find a notice board with the timetable at each stop They operate from about 5 00 clock to about 22 00 clock Night bus NitBus Both the metro and the buses do not run all night In Barcelona there is a fairly dense network of night buses to get you back to your hotel all night long Except for the line N0 all lines stop at Pla a Catalunya and can change there The N0 line is a circular line that allows you to circle around the city center and change to the other NitBus The night buses are operated by the private operator AMB which is why the Barcelona Card and Hola BCN Ticket are not valid The N17 line goes to the airport The operating hours of the NitBus are different for each line but they run from about 22 00 to 05 00 clock COVID 19 Related Questions What do I need to bring in order to access the conference Negative antigen PCR COVID 19 test not older than 24h for antigen and 72h for PCR tests OR valid proof of vaccination Vaccines authorized by EU or WHO by the event s date OR valid proof of recovery accreditation that you have passed COVID less than 6 months before the event Your ID document passportA medicinal mask either surgical or FFP2 What kind of masks must be worn onsite A medicinal mask either surgical or FFP2 the latter is recommended to be worn at all times indoors except when eating or drinking and especially when in the auditorium or at the registration desk Do I need to wear a mask outside of the conference venue Masks must be worn in the following areas Public and passenger transport On platforms and stations it is not necessary to carry it Hospitals health centers and pharmacies Residences workers and visitors It is also recommended that people with a positive diagnosis of covid 19 or with compatible symptoms and vulnerable people who are unable to maintain a minimum safety distance For more information please check https web gencat cat ca activem restriccions territorials catalunya bloc1 Which COVID 19 vaccines are recognised in Spain Any vaccine authorised by the European Union European Medicines Agency EMA and WHO will be accepted Certificates with vaccines not authorised by these agencies are also acceptable but the last dose administered must be of one of the authorised vaccines Complete vaccination schedules are defined as those established in the COVID 19 Vaccination Strategy in Spain What is the validity of vaccination proof in Spain From 1 February 2022 proof of vaccination is valid from 14 days after the date of administration of the last dose of the complete vaccination schedule and will be valid up to 270 days from the date of administration of that last dose Thereafter in order to be valid the vaccination certificate must reflect the administration of a booster dose These certificates will be considered valid since the day the booster dose was administered What is the validity of proof of recovery in Spain Certificate of Recovery corresponds to a test no more than 180 days after the date of the first positive NAAT test result and no earlier than the 11th day following the date of that positive test result The certificate must state the date of the first positive test Do I need to register and quarantine when arriving in Spain You can find the latest information on entry and entry requirements for Spain on the Spain Travel Health Website Please make sure to carefully read the information and to comply with all requirements and to carry the necessary supporting documentation Where can I get tested for COVID 19 in Barcelona and how much does it cost An antigen rapid test costs approximately 35 45 a PCR test approximately 85 100 You can also find more information about the different tests and links to some test centres here Costs of the test must be covered by the participants What if I test positive during the event If during the conference you test positive or develop symptomsassociated with COVID 19 such as reduced sense of smell and taste chills sore throat muscle aches headache general weakness diarrhea or vomiting you should 1 Refrain from coming to the event or leave promptly2 Contact the health service contact the corresponding health authorities of the Autonomous Communities by telephone If you feeling that the illness is serious you have shortness of breath or chest pain call 1123 Call 933 038 158 where they will also assist you in English What are the current local restrictions e g public transport restaurants or cafes Where can I find more information Specific rules and restrictions for Catalonia can be found here https web gencat cat ca activem restriccions territorials catalunya bloc1 Further information is also available via https spth gob es faq tab 2 Sponsors Bronze sponsor Media partners Development a The Company of Biologists journal International Union of Biochemistry and Molecular Biology Molecular Systems Biology an EMBO Press journal Open Biology a Royal Society journal Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage...

EMBO Workshop

EMBL Barcelona

4 May 2022

PDBe-KB Aggregated Views: providing biological insights into 3D structures

Edit

May 04, 2022 15:302022WebinarVirtual

Description The Protein Data Bank in Europe Knowledge Base PDBe KB https pdbe kb org is an open collaboration between world leading specialist data resources with a goal to provide biological insights to macromolecular structure data in Protein Data Bank PDB Since we described PDBe KB in 2019 there have been significant improvements in the variety of available annotation data sets and user functionality This webinar presents the up to date improved PDBe KB protein specific aggregated views which provide an overview of available structural and functional information for a protein of interest referenced by a UniProtKB accession...

Preeti Choudhary

Virtual

2 May - 6 May 2022

Hands-on flow cytometry: learning by doing!

Edit

May 02, 2022 00:002022CourseEMBL Heidelberg

Description OverviewSpeakers and TrainersProgrammePractical InformationSponsors Overview Proof of COVID 19 vaccination or recovery is required to attend this on site course Please see EMBL s COVID 19 safety policy for on site events Course Overview Flow Cytometry is one of the most powerful single cell analysis methods used throughout the life sciences and medicine By utilising Flow Cytometry we can identify and quantify specific cell populations from heterogeneous samples analyse the cell cycle or proliferation state or simply detect the expression of fluorescent reporters In line with the suggestions from our course in 2019 we will significantly enhance the number of analysis sessions together with our partners from FlowJo We will cover the theory of Flow Cytometry and corroborate this information intensively with the practical issues of the most frequent assays as part of our practical course curriculum Audience The course is designed for researchers at any step of their career and will cover the subject from basic principles to complex assays Prior basic working knowledge of Flow Cytometry data acquisition or analysis software DIVA FlowJo is of advantage but not strictly a must Modules Resources In depth principles of Flow CytometryQuality assessment and instrument validationAnalysis of cell cycle profiles in fixed and live cellsProliferation and cell division assessmentApoptosis assaysTissue staining of cell surface and intracellular antigensPrinciples and guidelines for experimental design especially for multi colour Flow CytometryEssential of gating and gating controlsDetailed multi sessions on analysing data from Flow Cytometers in cooperation with FlowJoGuidelines to prepare flow cytometry data for publication Learning Outcomes Our goal for this course is to teach the basic of this technology with a very big emphasis on practical work at the instruments Nothing is better than learning by doing We have a great set of experienced trainers in this technology delivering lectures and accompanying you into the lab doing flow on your own We will have support from FlowJo delivering the basics and some advanced features in multiple sessions This in depth five day course will push your knowledge and skills preparing you for any flow projects ahead on your research path What past participants say about this course A comprehensive and interactive course that I would recommend to everyone that uses flow cytometry in their work Oana Baldasici The Oncology Institute Prof Dr I Chiricuta Romania Speakers and Trainers Jochen Barths ProSort France Michael Bonadonna EMBL Heidelberg Germany Cora Chadick Amsterdam UMC location VUmc The Netherlands Virtual Speaker Gelo dela Cruz Novo Nordisk Foundation Center for Stem Cell Medicine reNEW Denmark Daniel Gimenes EMBL Heidelberg Germany Diana Ordonez EMBL Heidelberg Germany Ioannis Panetas BD Germany Virtual Speaker Steffen Schmitt German Cancer Research Center Germany Neda Tafrishi Sony Biotechnology Inc Germany Scientific Organisers Andrew Filby Newcastle University UK Cora Chadick Amsterdam UMC location VUmc The Netherlands Diana Ordonez EMBL Heidelberg Germany Malte Paulsen Novo Nordisk Foundation Center for Stem Cell Medicine reNEW Denmark Steffen Schmitt German Cancer Research Center Germany Course Organisers Maria Mercedes Bacadare Goitia Course and Conference Manager EMBL Heidelberg Germany Yvonne Yeboah Training Laboratory Manager EMBL Heidelberg Germany Programme Got something to say Tweet it with EMBLCytometry Some pre course work such as watching pre recordings protocol reading and computational exercises with estimated time 0 10 hours will be required and will be shared in advance of the course Some speakers may need to join virtually to give their lecture or Q A and the programme is subject to change All times in the programme below are shown as the time in Europe Berlin Day 1 Monday 2 May 2022 TimeSpeakerLocation08 40 09 00Bus from ISG to EMBLHotel entrance09 00 10 00Welcome Introduction and Safety briefingCourtyard Room A B10 00 10 45Participants flash talksCourtyard Room A B 10 45 11 15Coffee Break Flex Lab A B11 15 12 00Lecture Fluidics and opticsGelo dela Cruz Novo Nordisk Foundation Center for Stem Cell Medicine reNEW DenmarkCourtyard Room A B12 00 13 30LunchEMBL Canteen 13 30 14 15Lecture Fluorescence and PMTs detectors data generation and data displaySteffen Schmitt German Cancer Research Center GermanyCourtyard Room A B14 15 14 45Coffee Break Flex Lab A B 14 45 15 30Lecture Data generation and data displayGelo dela Cruz Novo Nordisk Foundation Center for Stem Cell Medicine reNEW DenmarkCourtyard Room A B15 30 17 15Practical 1 Practical Session I Assessing instrument performanceTraining Lab A B17 15 17 45Coffee break Flex Lab A B 17 45 19 30Practical Session 2 Absolute counting and proliferationTraining Lab A B19 30 21 00DinnerEMBL Canteen21 00 21 15Departure to HotelATC Entrance Day 2 Tuesday 3 May 2022 TimeSpeakerLocation08 40 09 00 Bus from ISG to EMBL Hotel entrance09 00 10 00Lecture Fluorescence spillover and compensationCora ChadickAmsterdam UMC location VUmc The Netherlands Virtual Speaker Courtyard Room A B10 00 10 30Coffee BreakFlex Lab A B 10 30 11 15Lecture Experimental design for multi color flowDiana Ordonez EMBL Heidelberg GermanyCourtyard Room A B11 15 12 00Lecture Spectral Flow CytometryNeda Tafrishi Sony Biotechnology Inc GermanyCourtyard Room A B 12 00 13 30LunchEMBL Canteen 13 30 15 30Practical Multi color staining Group 1 Practical Data analysis with FlowJo Group 2 Group 1 Training Lab A B Group 2 Courtyard Room A B15 30 16 00Coffee Break16 00 18 00Practical Data analysis with FlowJo Group 1 Practical Multi color staining Group 2 Group 1 Courtyard Room A BGroup 2 Training Lab A B 18 00 19 00Lecture Tips and tricks for intracellular stainingDiana Ordonez EMBL Heidelberg Germany Courtyard Room A B19 00 19 15Departure to RestaurantATC Entrance 19 15 21 30DinnerRestaurant Day 3 Wednesday 4 May 2022 Time SpeakerLocation08 40 09 00 Bus from ISG to EMBL Hotel entrance 09 00 10 00Lecture The Essentials of gating FMO and gating controlsDaniel Gimenes EMBL Heidelberg GermanyCourtyard Room A B10 00 10 30Coffee Break Flex Lab A B 10 30 12 00Lecture Cell CycleDiana Ordonez EMBL Heidelberg GermanyCourtyard Room A B12 00 13 30LunchEMBL Canteen 13 30 13 40Group Picture13 40 15 40Practical Measuring cell cycle samples Group 1 Practical Data analysis with FlowJo Group 2 Group 1 Training Lab A B Group 2 Courtyard Room A B15 40 16 10Coffee BreakFlex Lab A B 16 10 18 10Practical Data analysis with FlowJo Group 1 Practical Measuring cell cycle samples Group 2 Group 1 Courtyard Room A BGroup 2 Training Lab A B18 10 18 40Q A SessionCourtyard Room A B18 40 20 00DinnerEMBL Canteen 20 00Departure to HotelATC Entrance Day 4 Thursday 5 May 2022 TimeSpeakerLocation08 40 09 00 Bus from ISG to EMBL Hotel entrance 09 00 10 00Practical Data analysis cell cycle FlowJoCourtyard Room A B10 00 10 30Coffee BreakFlex Lab A B10 30 12 00Practical Data analysis with FlowJo Users data Courtyard Room A B12 00 13 30LunchEMBL Canteen 13 30 14 30Lecture Assessing cell deathSteffen Schmitt German Cancer Research Center GermanyCourtyard Room A B14 30 16 00Practical Measuring apoptosis labellingTraining Lab A B16 00 16 30Coffee BreakFlex Lab A B16 30 18 40Practical Data analysis with FlowJoCourtyard Room A B18 40 Departure to HotelATC Entrance19 00Social Activity and DinnerISG Hotel Day 5 Friday 6 May 2022 TimeSpeakerLocation08 40 09 00 Bus from ISG to EMBL Hotel entrance 09 00 10 00Lecture Basics of cell sortingJochen Barths ProSort FranceCourtyard Room A B10 00 10 30Coffee BreakFlex Lab A B10 30 12 30Practical Cell sorting and reanalysis of sorted cellsTraining Lab A B12 30 14 00LunchEMBL Canteen 14 00 15 00Lecture High dimensional data analysis with FlowJoIoannis Panetas BD Germany Virtual Speaker Courtyard Room A B15 00 15 30Feedback and GoodbyeCourtyard Room A B15 30 16 00Departure to Hotel Heidelberg Train StationATC Entrance Practical Information Registration Fees and Motivation Letter The course is limited to 12 participants For selection purposes please note that your application will not be considered without a letter of motivation Registration Registration Fees include admission course materials COVID 19 safety measures meals and coffee breaks Participants are expected to book and pay their own accommodation and travel expenses Academia 600PhD Student 600Industry 1100 Confirmation and Payment The registration fee should be paid only after acceptance to the course The results will be announced approximately 2 3 weeks after the application deadline Motivation Letter Submission After you have logged in and successfully registered you will receive an email asking you to submit your motivation letter Click on the link provided and enter your motivation letter in the text box provided Alternatively you can submit your motivation letter by clicking on the link on the confirmation page directly after registering Instructions Include your relevant skills experience and qualifications showing why you would be suitable for the course Explain why you would like to attend including what you can contribute and how you think you will benefit from the course Please note The limit of 2000 characters refers to manually typed text and excludes spaces If an error occurs try using a different web browser preferably Google Chrome or Mozilla Firefox If you copy paste the text into the form hidden formatting might still be included which may cause the text to exceed the 2 000 character limit resulting in an error message We recommend you clear all formatting before pasting in the text If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised For more detailed information follow the instructions provided in our video on how to submit a course motivation letter Further Details For further information about registration and motivation letter submission please refer to the FAQ page Financial Assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of both registration fee waivers and travel grants Availability is limited to participants attending on site events in Heidelberg and will be indicated during the abstract or motivation letter submission process Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Registration Fee Waiver The fee waiver will cover the registration sum that you have paid to attend the course or conference Travel Grant The travel grant will cover the cost of travel airfare train bus taxi accommodation visa and or registration fees and is provided up to specified caps which are normally as follows up to 400 for participants travelling to an EMBL Course EMBL Conference or EMBO EMBL Symposium from within Europe up to 1000 for participants travelling to an EMBL Course EMBL Conference or EMBO EMBL Symposium from outside Europe up to 500 for any participant travelling to an EMBO Practical Course or EMBO Workshop up to 1000 for any participant working in Chile India Singapore or Taiwan travelling to an EMBO Practical Course or EMBO Workshop Registration fees are only covered for EMBO Practical Courses or EMBO WorkshopsThe organisers may reduce the grant cap to accommodate more participants Recipients will be notified of their travel cap amount when they are informed of the outcome of their application Original receipts must be provided with your signature for all costs incurred within two months of completion of travel Scanned copies cannot be accepted Boehringer Ingelheim Fonds Travel Grant Applies to selected courses only Availability will be indicated during the abstract or motivation letter submission process This grant covers costs related to your attendance to the course registration travel and accommodation costs The grant is restricted to PhD students and postdocs who conduct basic biomedical research Whether you are eligible to apply for a travel grant depends on when you received your university entrance qualification e g Abitur A Levels High School Diploma Final State Examination for PhD and MD students as well as graduates the university entrance qualification must not have been obtained more than 11 years ago at the time of the envisaged course for postdocs the university entrance qualification must not have been obtained more than 13 years ago at the time of the envisaged course Application You may apply for financial assistance when submitting your motivation letter for courses and abstract for conferences In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application For the Boehringer Ingelheim Fonds Travel Grant there is a pre application question during the motivation letter submission process and if selected you will be requested to complete a standard form and documentation consisting of your travel expense estimation Selection The scientific organisers will select the recipients of all financial assistance during the motivation letter or abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection is based on your current work or study location the reasons for needing financial support and the impact this event will have on your career Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details View our list of external funding opportunities and information on attending a conference as an event reporter For further information about financial assistance please refer to the FAQ page Accommodation and Shuttles Single rooms have been reserved for 6 nights 1 6 May 2022 at the ISG Hotel After the selection process selected participants should contact the hotel directly to make a booking booking code CYT22 01 We recommend that all course participants stay at the ISG Hotel which is the dedicated hotel for the course Local transport Shuttle buses will go from the ISG Hotel to EMBL and back mornings and evenings A bus schedule and location of the bus stops will be made available prior to the meeting Further Details Address EMBL Heidelberg Meyerhofstra e 1 69117 Heidelberg GermanyFor further information on getting to EMBL Heidelberg visit our Travel Information page For enquiries about accommodation and local transportation please refer to the FAQ page Technical Requirements and Event Software Technical Requirements Below you will find the software and technical requirements for this course Participants need to bring their own laptops which will be used to remotely access EMBL virtual machines with pre installed software You will need admin rights to install the software required to access the virtual machines If you do not have admin rights please contact your technical support team in advance to make sure the software can be installed If you have a non standard HDMI port other than type A you need to bring an adaptor Keyboard and PC mouse are available for use with a standard USB port If you have a different port type such as USB C you will need to bring your own Event Software The EMBL eCampus learning platform will be used to collaborate communicate and network with all of the course participants All participants will receive information on how to join shortly before the course We recommend using Chrome Safari or Mozilla Firefox browsers for eCampus Additional Information Please find additional information including FAQs terms and conditions COVID 19 safety policy and travelling to EMBL on our Information for Participants page COVID 19 Related Questions COVID 19 information for onsite events at EMBL Heidelberg can be found in our COVID 19 FAQs Sponsors Sponsorship Opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage...

Andrew Filby, Diana Ordonez, Malte Paulsen, Steffen Schmitt

EMBL Course

EMBL Heidelberg

27 April 2022

Approaches for using protein-protein interaction networks for biological discovery

Edit

April 27, 2022 15:302022WebinarVirtual

Description It is hard to think of a biological process in which protein protein interactions PPIs do not play an essential role Thus in collective efforts over the last two decades comprehensive sets of human PPIs have been curated from the scientific literature or identified in systematic proteome wide mapping efforts These resources build large PPI networks with an amazing potential to advance our understanding of individual gene function towards a systems understanding of cellular organisation This webinar will provide important insights into technical biases that should be considered when using PPI data for system wide analyses It will explain theory and practical considerations when performing statistical tests on PPI networks to determine whether selected proteins i e that share a disease association tend to interact with each other or for the prediction of gene function using guilt by association principles...

Katja Luck

Virtual

26 April 2022

Mathematical modelling as knowledge mapping in PhysiCell: a guided tour

Edit

April 26, 2022 15:002022WebinarVirtual

Description Tissues are complex multiscale biological systems where cells communicate to modulate their behaviour in response to dynamical microenvironmental conditions Small perturbations to cells such as injuries or therapy can have unanticipated ripple effects that percolate through the system We can use computational models as virtual laboratories to explore these complex systems In this talk we will introduce PhysiCell an open source agent based modelling platform that can simulate many individual cell agents as they interact in tissue with multiple diffusing chemical signals We will give examples drawn from hypoxic cancer invasion mechanics driven reawakening of dormant micrometastases and innate and adaptive immune responses to viral pathogens like SARS CoV 2 and tumour micrometastases We will close with new developments and a live demonstration to integrate knowledge mapping directly into the modelling process where expert driven biological hypotheses chemical signal X increases cell behaviour Y are directly transformed into mathematics and code In our vision multidisciplinary teams will curate biological knowledge to jointly develop mathematical models in real time to better evaluate our knowledge gaps and exploit our knowledge to treat disease About the speaker Paul Macklin is an Associate Professor of Intelligent Systems Engineering at Indiana University IU His team the Math Cancer Lab develops open source computational tools for multicellular systems biology such as BioFVM for multi substrate diffusion and PhysiCell for large scale agent based simulations in 3 D tissues He has worked closely with others to develop new capabilities for the PhysiCell platform The codes developed have been applied to diverse problems in cancer biology nanotherapy tissue engineering immunology cryobiology synthetic systems and microbiology...

Paul Macklin

Virtual

25 April 2022

Exploring parasite biology through their protein annotation in UniProtKB

Edit

April 25, 2022 15:002022WebinarVirtual

Description Parasitic infections cause a major global burden in terms of human health whilst also affecting livestock and agriculture Understanding their biology is essential to identify potential candidates for drug and vaccine development To support the scientific community in this effort the UniProt knowledgebase UniProtKB provides a comprehensive high quality and freely accessible resource of protein sequence and functional information for a wide range of species including parasites and their hosts and vectors This webinar part of a series covering various aspects of UniProt will give you an overview on what type of functional information we provide and how to search and retrieve it We will also describe the curation process including how we annotate sequence polymorphism the interaction between host and parasite proteins and how we highlight the potential biotechnological use of a protein To illustrate these various aspects we will use the parasite P falciparum the causative agent of malaria as an example...

Rossana Zaru

Virtual

23 April - 29 April 2022

Methods for analysis of circRNAs: from discovery to function

Edit

Edit

April 06, 2022 00:002022ConferenceVirtual

Description OverviewSpeakersProgrammePractical InformationSponsorsAbout Overview Please note that this event will now take place virtually Symposium Overview Microbial host interaction has a profound impact on numerous biological systems including metabolism immunology DNA integrity and nutrition Pathobionts and pathogenic bacteria have developed specific abilities to gain growth advantage and niche resilience which affect these key host biological processes often leading to disease states such as cancer While the connection between helicobacter infection and gastric cancer was originally considered an exception many new examples of bacterial infection contributing to cancer have been identified This symposium brings together the leading scientists in the field of microbial ecology immunology metabolism genomics and infection to discuss the latest progress in microbial infection and cancer from an interdisciplinary perspective This conference will provide a larger audience of young researchers and students with a stimulating platform to present their research to network and to develop this emerging and exciting field further Session Topics Bacterial genomics and cancer Bacterial metabolism and cancer Microbiome in infection and cancer Bacteria and immune responses Bacteria and mammalian cell proliferation transformation Bacteria and therapeutic responses Speakers Keynote Speakers Hans Clevers Hubrecht Institute The Netherlands Eran Elinav German Cancer Research Center DKFZ Germany Speakers Yasmine Belkaid National Institutes of Health USA Andreas Diefenbach Charit Germany Wendy Garrett Harvard T H Chan School of Public Health USA Masanori Hatakeyama The University of Tokyo Japan Brendan Jenkins Hudson Institute of Medical Research Australia James Kinross Imperial College London UK Anne M ller University of Zurich Switzerland Serena Nik Zainal University of Cambridge UK Thomas Rudel University of W rzburg Germany Ramona Schulz Heddergott University of G ttingen Germany Nicola Segata University of Trento Italy Jun Sun University of Illinois College of Medicine USA Britton Trabert University of Utah Huntsman Cancer Institute USA Jun Yu The Chinese University of Hong Kong China Georg Zeller EMBL Heidelberg Germany Laurence Zitvogel Gustave Roussy France Scientific Organisers Achim Breiling EMBO Reports Germany Christian Jobin University of Florida USA Xin Lu University of Oxford UK Thomas F Meyer Max Planck Institute for Infection Biology Germany Jacques Neefjes Leiden University The Netherlands Conference Organisers Chris Stocks EMBL Heidelberg Germany Maryann Heck EMBL Heidelberg Germany Programme Got something to say Tweet it EESMicrobialInfections The virtual conference includes live streamed invited speakers and short talk presenters with Q A sessions after each talk as well as Panel Discussion sessions All digital poster presenters are encouraged to upload a recorded flash talk or narration with their digital poster and to be present during their poster session time to present to participants Information on the live stream and access to the discussion platform and digital posters will be provided shortly before the start of the event Access to the recorded talks will be available for 2 weeks after the start of the event All times in the programme below are shown as the time in Europe Berlin To find out the equivalent time zone in your location enter Berlin the programme time and date along with your city into the Time Zone Converter Day 1 Wednesday 6 April 2022 TimeTitle 14 00 14 15 Opening remarks14 15 15 00Keynote lecture 1 Stem cell based organoids in human diseaseHans Clevers Roche Innovation Center SwitzerlandAVAILABLE ON DEMAND AFTER LIVE STREAM15 00 17 30Session 1 Microbiome in infection and cancerSession chairs Xin Lu James Kinross15 00 15 25Microbiome control of host immunityYasmine Belkaid National Institutes of Health USAAVAILABLE ON DEMAND AFTER LIVE STREAM15 25 15 40Host microbiota interactions during colorectal cancer developmentLars Vereecke Ghent University BelgiumAVAILABLE ON DEMAND AFTER LIVE STREAM15 40 15 55Deficiency in mismatch repair MMR pathway increases susceptibility to colibactin induced colorectal cancerAlberto Martin University of Toronto CanadaAVAILABLE ON DEMAND AFTER LIVE STREAM15 55 16 10Break16 10 16 35Gut microbial co metabolism determines the efficacy and toxicity of chemotherapyJames Kinross Imperial College London UK AVAILABLE ON DEMAND AFTER LIVE STREAM 16 35 16 50Diet induced luminal nitrates selectively enrich genotoxic E coli to induce colibactin dependent colon carcinogenesisBupesh Kumar Thakur University of Toronto CanadaAVAILABLE ON DEMAND AFTER LIVE STREAM16 50 17 15Innate lymphoid cells adapt intestinal epithelial stem cells to genotoxic stressAndreas Diefenbach Charit Universit tsmedizin Berlin Germany AVAILABLE ON DEMAND AFTER LIVE STREAM 17 15 17 30Multi omics analyses reveal multimodal Fusobacterium DNA damage perturbations in colorectal cancerRadhika Kataria King s College London UKAVAILABLE ON DEMAND AFTER LIVE STREAM17 30 18 00Break and meet the speakers18 00 18 45Poster session18 45 19 55Session 2 Bacterial genomics and cancerSession chairs Jun Yu Achim Breiling18 45 19 00Association of Helicobacter pylori and autoimmune gastritis with stomach cancer in a cohort of young Finnish womenJulia Butt DKFZ Heidelberg GermanyAVAILABLE ON DEMAND AFTER LIVE STREAM 19 00 19 15Mechanistic insight into Colibactin as a mutagenic driver of cancerHilmar Berger University of Kiel GermanyAVAILABLE ON DEMAND AFTER LIVE STREAM19 15 19 30Improved detection of colibactin linked mutations in human cancerJens Puschhof German Cancer Research Center Hubrecht Institute GermanyAVAILABLE ON DEMAND AFTER LIVE STREAM19 30 19 55Metagenomics for the study of the microbiome cancer interactionNicola Segata University of Trento Italy AVAILABLE ON DEMAND AFTER LIVE STREAM 19 55 20 55Speed networking Day 2 Thursday 7 April 2022 TimeTitle 13 00 14 00 Poster session14 00 15 35 Session 2 Bacterial genomics and cancer continued Session chairs Jun Yu Achim Breiling14 00 14 25Induction of BRCAness by the Helicobacter pylori CagA oncoproteinMasanori Hatakeyama The University of Tokyo JapanAVAILABLE ON DEMAND AFTER LIVE STREAM14 25 14 40A Fecal Microbiota Signature with High Specificity for Pancreatic CancerEce Kartal Heidelberg University GermanyAVAILABLE ON DEMAND AFTER LIVE STREAM14 40 14 55Repetitive Exposure to Non Typhoidal Salmonellae is an Environmental Risk Factor for Colon CancerDaphne van Elsland Leiden University Medical Centre The NetherlandsLIVE STREAM ONLY14 55 15 10Gut microbiome in colorectal cancer basic research and clinical translationJun Yu The Chinese University of Hong Kong ChinaAVAILABLE ON DEMAND AFTER LIVE STREAM15 10 15 35Campylobacter jejuni derived cytolethal distending toxin promotes cancer metastasis through the activation of MMP9 by JAK2 STAT3 signalingZhen He Sixth Affiliated hospital of Sun Yat sen University ChinaAVAILABLE ON DEMAND AFTER LIVE STREAM15 35 16 05Break and meet the speakers16 05 17 40Session 3 Bacterial metabolism and cancerSession chairs Thomas Rudel16 05 16 20Fusobacterium nucleatum secretes amyloid FadA as a molecular switch for commensal to pathogen conversionYiping Han Columbia University USAAVAILABLE ON DEMAND AFTER LIVE STREAM16 20 16 35The intestinal microbiota modulates pancreatic carcinogenesis through intratumoral natural killer cellsRyan Thomas University of Florida USAAVAILABLE ON DEMAND AFTER LIVE STREAM16 35 17 00Microbiome metabolic pathways reveal a diet microbe link for enhancing colon cancer immunityWendy Garrett Harvard T H Chan School of Public Health USALIVE STREAM ONLY17 00 17 15Microbiome host crosstalk analysis unravels formate as an oncometabolite in colorectal cancerElisabeth Letellier University of Luxembourg LuxembourgAVAILABLE ON DEMAND AFTER LIVE STREAM17 15 17 40Tumor metabolisms mimic Metabolic reprogramming as a driver for bacterial infectionThomas Rudel Julius Maximilians Universit t W rzburg GermanyLIVE STREAM ONLY17 40 18 10Break and Meet the speakers18 10 18 55Keynote lecture 2 Host micro biome interactions in health and diseaseEran Elinav German Cancer Research Center GermanyLIVE STREAM ONLY18 55 20 25Session 4 Bacteria and therapeutic responsesSession chairs Jun Sun Christian Jobin18 55 19 20Intestinal barriers inhibit microbial infection and colon cancerJun Sun University of Illinois USAAVAILABLE ON DEMAND AFTER LIVE STREAM19 20 19 35Gut microbiota that render an anti tumor responseRabi Upadhyay New York University School of Medicine USAAVAILABLE ON DEMAND AFTER LIVE STREAM19 35 20 00Serologic markers of infection and cancer risk in the upper genital tract expanding evidenceBritton Trabert University of Utah Huntsman Cancer Institute USAAVAILABLE ON DEMAND AFTER LIVE STREAM20 00 20 15The gut cancer dialogue governing tumor immunosurveillanceLaurence Zitvogel University Paris Saclay FrancePRE RECORDED TALK 20 15 20 45Meet the speakers20 45 21 45Bar mixer Day 3 Friday 8 April 2022 Time Title14 00 16 30 Session 5 Bacteria and immune responsesSession chairs Jacques Neefjes Britton Trabert14 00 14 15 Interaction of bacterial genera associated with therapeutic response to immune checkpoint PD 1 blockade in a United States cohortRachel Newsome University of Florida USAAVAILABLE ON DEMAND AFTER LIVE STREAM14 15 14 40 Uncovering the pro tumourigenic role of innate immune DNA sensors in gastric cancerBrendan Jenkins Hudson Institute of Medical Research AustraliaAVAILABLE ON DEMAND AFTER LIVE STREAM14 40 15 05How Salmonella contributes to colon and gallbladder cancerJacques Neefjes Leiden University The NetherlandsAVAILABLE ON DEMAND AFTER LIVE STREAM 15 05 15 20Battle for the Endoplasmic Reticulum Host versus Pathogen Paulomi Sanghavi Tata Institute of Fundamental Research IndiaAVAILABLE ON DEMAND AFTER LIVE STREAM15 20 15 35 The role of morphogen signals in shaping healthy and infected precancerous gastric mucosa Francesco Boccellato University of Oxford UKAVAILABLE ON DEMAND AFTER LIVE STREAM15 35 16 00Co infections modulate H pylori induced gastric preneoplasiaAnne M ller University of Z rich SwitzerlandAVAILABLE ON DEMAND AFTER LIVE STREAM16 00 16 30Break and Meet the speakers16 30 18 45Session 6 Bacteria and mammalian cell proliferation transformationSession chairs Anne Muller Rachel Newsome16 30 16 55Aetiologies of mutational signatures in human cancer from infection to endogenous abnormalitiesRamona Schulz Heddergott University of G ttingen Germany AVAILABLE ON DEMAND AFTER LIVE STREAM 16 55 17 10 Modeling Helicobacter pylori induced gastric carcinogenesis using wild type and genetically modified murine gastric organoidsJiazhuo He University of Z rich Switzerland AVAILABLE ON DEMAND AFTER LIVE STREAM 17 10 17 25Synthetic colibactin analogs promote specific transcriptomic and mutational changes in intestinal epithelial cellsMichael Dougherty University of Florida USAAVAILABLE ON DEMAND AFTER LIVE STREAM17 25 17 50Gut microbiota signatures of colorectal cancerGeorg Zeller EMBL Heidelberg GermanyAVAILABLE ON DEMAND AFTER LIVE STREAM17 50 18 05Ectopic expression of H pylori CagA in human gastric organoids leads to intestinal differentiationMar Reines Max Planck for Infection Biology GermanyAVAILABLE ON DEMAND AFTER LIVE STREAM18 05 18 20 Dysregulated endolysosomal trafficking in cells arrested in the G1 phase of the host cell cycle impairs Salmonella vacuolar replicationAna Eulalio CNC University of Coimbra PortugalAVAILABLE ON DEMAND AFTER LIVE STREAM18 20 18 45Aetiologies of mutational signatures in human cancer from infection to endogenous abnormalities Serena Nik Zainal The University of Cambridge UK AVAILABLE ON DEMAND AFTER LIVE STREAM 18 45 19 10Break and Meet the speakers19 10 19 25 Closing Remarks Practical Information Registration Fees and Abstract Submission Registration Fees include access to all of the talks digital poster sessions and online group discussions and help us cover our costs to run the event For further information please refer to the FAQ page PhD Student 140 Academia 190Industry 240 Accredited journalists may be eligible to register for a complimentary registration Registrants may be required to provide accreditation or equivalent proof of press membership after registration Please contact Christopher Stocks for more information Confirmation and Payment Types of payments accepted are international bank transfers and credit card payments Abstract submission Abstract submission deadline Wednesday 16 February 2022 Only registered participants are eligible to submit an abstract We only accept online abstract submissions After you have logged in and successfully registered you will receive an email asking you to submit your abstract Click on the link provided and enter your abstract in the text box provided Alternatively you can submit your abstract by clicking on the link on the confirmation page directly after registering The same login credentials are used for both processes When submitting your abstract you can also apply for an oral or poster presentation A selection process will take place with the results announced 2 3 weeks after the abstract submission deadline Please note Title The title should not exceed 20 words Only the first word of the title should start with a capital letter and the rest of the title should be in lowercase Authors and Affiliations Please fill in the author s details as requested in the online form The compulsory details are First Name Last Name Organisation Name Affiliation or Company Country and Email Mark only one author as the role of First author and please don t forget to indicate who will be presenting The order of the authors will be listed as follows First Author Co First Author alphabetically if multiple co author s in the order added by the submitter Presentation Types When submitting your abstract you can apply for an oral or poster presentation A selection process will take place with the results announced 2 3 weeks after the abstract submission deadline Please check our FAQs pages for further information on how to submit an abstract Financial Assistance Registration Fee Waiver All academic and student registrants are invited to apply for a registration fee waiver provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO The registration fee waiver covers the registration sum that you have paid to attend the meeting Conference participants are not required to pre pay the registration fee to be selected for a fee waiver for a virtual meeting If you have already paid the registration fee and are awarded a fee waiver it will be reimbursed after the meeting The fee waiver will cover the registration sum that you have paid to attend the course or conference Childcare Grant For participants and speakers with childcare responsibilities there is the possibility to apply for a grant provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO to offset childcare costs incurred when participating at a virtual event Eligible costs include fees for a babysitter or childcare facility or travel costs for a care giver Please note that priority will be given to early stage researchers Costs will be reimbursed after the meeting only once a reimbursement form and original receipts have been received Attendance at the event is required in order to be eligible to receive the reimbursement In order to apply for this grant you must be registered by the abstract submission deadline Application You may apply for financial assistance when submitting your motivation letter for courses and abstract for conferences In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application For the Boehringer Ingelheim Fonds Travel Grant there is a pre application question during the motivation letter submission process and if selected you will be requested to complete a standard form and documentation consisting of your travel expense estimation Selection The scientific organisers will select the recipients of all financial assistance during the motivation letter or abstract selection process Results will be announced approximately 6 8 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection is based on your current work or study location the reasons for needing financial support and the impact this event will have on your career Reimbursement Costs will be reimbursed after the meeting only once a reimbursement form and original receipts from travel costs have been received Further details View our list of external funding opportunities and information on attending a conference as an event reporter For further information about financial assistance please refer to the FAQ page Accommodation and Shuttles Accommodation is not included in the conference registration fee As further changes in our events are possible due to COVID 19 you should book flights trains and hotels with flexible options and favourable cancellation conditions The hotels below have rooms on hold for participants until xxxx 2022 in some cases at special rates Please quote the booking code xx22 0x and confirm the exact price of the room with the hotel directly Hotel AnlageHotel ibis HeidelbergPremier Inn Heidelberg CityHotel Bayrischer Hof ISG Hotel Staycity Aparthotel HeidelbergB B HotelLeonardo Hotel Heidelberg City CentreSteffi s Hostel HeidelbergExzellenz Hotel Boarding HouseMeininger HeidelbergHotel Vier Jahreszeiten HeidelbergHotel Holl nder Hof Hotel Monpti Conference Shuttle Buses Conference shuttle buses are free of charge for participants and depart from designated bus stops near the hotels to EMBL and back mornings and evenings The bus stops for this conference are Kurf rsten Anlage Opposite Main Train Station Hotel Premier Kurf rsten Anlage 23Leonardo Hotel Bergheimer Str NeckarmuenzplatzPeterskircheISG Hotel View Conference shuttle bus stops and hotels in a larger map Please note that not every bus stop will be used for every event Further details Address EMBL Meyerhofstra e 1 69117 Heidelberg Germany For further information on getting to EMBL Heidelberg visit Public Transportation to the Venue For information about accommodation and local transportation please refer to the FAQ page Virtual Participation Guidelines Do not broadcast the conference to unregistered participants You are encouraged to tweet and post about the event Tweet unless the speaker specifically says otherwise but be mindful of unpublished data Please do not capture transmit or redistribute data presented at the meeting Additional information can be found in our Code of Conduct Health and well being It is important to stay healthy and move around especially when you are attending an event virtually We have put together a few coffee break stretches and yoga videos in the conference platform for you to enjoy during the event How to ask questions Please use the Q A function in the event platform If you have any other questions you can go to the Help Desk in the event platform Click on more on the top menu and click Help Desk Time zone The programme is planned based on the Europe Berlin time zone unless otherwise stated Please take your time zone into consideration when planning your attendance Additional Information Please find additional information including FAQs terms and conditions on our Information for Participants page Sponsors Media partners EMBO Molecular Medicine an EMBO Press journal International Union of Biochemistry and Molecular Biology Molecular Oncology a FEBSPRESS journal Open Biology a Royal Society journal Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage About EMBO EMBL Symposia promote scientific communication and collaboration in the European research area They provide scientists with a platform to discuss and exchange ideas on forward looking topics and new developments in the life sciences Topics emphasise upcoming developments and the interdisciplinary nature of related fields Jointly funded and organised by EMBO and EMBL and complementary to their respective courses workshops and conference programmes the symposia promote scientific communication and collaboration All symposia are held in the EMBL Advanced Training Centre ATC in Heidelberg Germany or virtually...

Achim Breiling, Christian Jobin, Xin Lu, Thomas Meyer, Jacques Neefjes

EMBO | EMBL Symposium

Virtual

5 April 2022

Working with sensitive data

Edit

April 05, 2022 15:302022WebinarVirtual

Description This webinar part of the biocuration series will introduce the concept of sensitive data for example data relating to individual patients It will also discuss how controlled data resources that contain sensitive data are able to archive and share the data with researchers and the best practices for assembling metadata for a rare disease submission To give an example of how controlled data resources work the European Genome phenome Archive EGA will be introduced The EGA is a resource that archives and shares all types of personally identifiable genetic and phenotypic data resulting from biomedical research projects The webinar will discuss why restricted access to the EGA s data is required what information about the data can be viewed by anyone and how researchers can gain access to the data they need This webinar is the fourth in our series of webinars on the topic of biocuration In an ELIXIR survey in 2019 which aimed at identifying training needs in biocuration the most commonly indicated were programming development and use of ontologies and database management In addition skills like programming and extracting data from literature were mentioned as decisive for a successful biocuration career With our webinar series we want to help to close this gap Bicourators from different backgrounds and institutes will share their experience on how they have acquired these relevant skills in their job how they apply these in their works and why they benefit from it The speakers will also point to helpful tools and resources they use...

Marcos Casado Barbero, Dona Shaju

Virtual

4 April - 8 April 2022

Data visualisation for biology

Edit

April 04, 2022 00:002022CourseEMBL-EBI

Description Please note that the dates set for this 2022 course are subject to change but all changes will be reflected on this course page To keep informed of changes to the course and to find out when the course opens for applications please register your interest...

EMBL-EBI Training team

EMBL-EBI

4 April - 8 April 2022

Gene expression at single-cell resolution

Edit

Edit

March 21, 2022 00:002022ConferenceVirtual

Description OverviewSpeakersProgrammePractical InformationSponsorsAbout Overview Please note that this event will now take place virtually Symposium Overview Like a machine any organism even the simplest is a functional unit coherent and integrated We are far from having elucidated in complex organisms the entire structure of these functional units A major outcome of research using model organisms has been to address this central question of biology that was stated so clearly and candidly by J Monod in 1969 Genetic studies in model organism have first revealed that we are far from knowing all the functions fulfilled by various organs in vertebrates or invertebrates In doing so this body of work has nonetheless led to unprecedented progress in our understanding of how homeostasis of an entire organism is maintained As a result modern physiology has slowly moved from a purely molecular discipline back to rediscovering its holistic nature The powerful combination of molecular and physiological approaches is revealing new insights into energy metabolism endocrinology cardiovascular and renal physiology as well as the regulation of cognitive and immune functions Symbiotic interactions with resident microbes have added a further dimension to the study of host physiology This symposium aims to provide a high visibility platform to scientists from multiple disciplines who use molecular genetic tools to probe inter organ communication signals that maintain homeostasis We anticipate that by bringing together scientists interested in various aspects of vertebrate and invertebrate animal physiology we will foster interactions between them that will accelerate the discovery of novel physiologies This meeting will also directly address a fundamental and long term goal of the study of physiology how can recent developments in whole organism physiology pave the way to novel adapted and efficient therapies for multiple degenerative diseases Session Topics Brain body crosstalkThe gut and its microbesFat and liver signalsImmune metabolic crosstalkNon canonical inter organ communication Speakers Keynote Speaker Ruslan Medzhitov Yale School of Medicine USA Speakers Ivan De Araujo Icahn School of Medicine at Mount Sinai USA Ralph DeBerardinis UT Southwestern Medical Center USA Ana Domingos University of Oxford UK Iqbal Hamza University of Maryland USA Shingo Kajimura Harvard Medical School and Beth Israel Deaconess Medical Center USA Gerard Karsenty Columbia University USA Stavroula Kousteni Columbia University USA Pierre Leopold Institut Curie France Dan Littman New York University USA Irene Miguel Aliaga MRC London Institute of Medical Sciences and Imperial College London UK Gilles Mithieux INSERM France Asya Rolls Technion Israel Institute of Technology Israel Miguel Soares Instituto Gulbenkian de Ci ncia Portugal Lisa Stowers Scripps Research USA Filip Swirski Icahn School of Medicine at Mount Sinai USA Henrique Veiga Fernandes Champalimaud Foundation Portugal Scientific Organisers Gerard Karsenty Columbia University USA Irene Miguel Aliaga MRC London Institute of Medical Sciences and Imperial College London UK Miguel Soares Instituto Gulbenkian de Ci ncia Portugal Conference Organiser Nathalie Sneider EMBL Heidelberg Germany Programme Got something to say Tweet it EESInterOrgan The virtual conference includes live streamed invited speakers and short talk presenters with Q A sessions after each talk as well as Panel Discussion sessions All digital poster presenters are encouraged to upload a recorded flash talk or narration with their digital poster and to be present during their poster session time to present to participants Information on the live stream and access to the discussion platform and digital posters will be provided shortly before the start of the event Access to the recorded talks will be available for 2 weeks after the start of the event All times in the programme below are shown as the time in Europe Berlin To find out the equivalent time zone in your location enter Berlin the programme time and date along with your city into the Time Zone Converter Day 1 Monday 21 March 2022 TimeSpeaker14 00 14 15Opening remarks by Scientific Organisers14 15 17 05Session 1 Non canonical inter organ communicationChairs Iqbal Hamza and Irene Miguel Aliaga 14 15 14 40Intestinal gluconeogenesis what was the purpose of natural selection Gilles Mithieux INSERM France AVAILABLE ON DEMAND AFTER LIVE STREAM 14 40 14 55Extracellular vesicle mediated transfer of functional molecules from periphery to brain in vivoStefan Momma Goethe University Frankfurt GermanyAVAILABLE ON DEMAND AFTER LIVE STREAM 14 55 15 20Towards a molecular definition of bone driven acute myeloid leukemiaStavroula Kousteni Columbia University USAAVAILABLE ON DEMAND AFTER LIVE STREAM 15 20 15 35Identification of kidney injury released circulating osteopontin as causal agent of respiratory failureAndreas Herrlich Washington University School of Medicine in St Louis USAAVAILABLE ON DEMAND AFTER LIVE STREAM 15 35 15 50Break15 50 16 15Metabolic outliers in human diseaseRalph DeBerardinis UT Southwestern Medical Center USAAVAILABLE ON DEMAND AFTER LIVE STREAM 16 15 16 30Tribbles pseudokinase regulates metabolism and sleepRebeka Popovic University of Cambridge UKAVAILABLE ON DEMAND AFTER LIVE STREAM 16 30 16 55Long range signaling at the intestinal neural axis promotes organismal heme homeostasisIqbal Hamza University of Maryland USAONLY AVAILABLE TO VIEW LIVE16 55 17 00Transition to Panel Discussion17 00 17 30Panel Discussion Session 1Chairs Iqbal Hamza and Irene Miguel Aliaga ONLY AVAILABLE TO VIEW LIVE 17 30 18 00Break18 00 19 00Poster Session 1 A O 19 00 19 05Transition to Session 219 05 21 20Session 2 Brain body crosstalk Chairs Ralph DeBerardinis and Ivan De Araujo 19 05 19 30 Inter organ neural circuits for reward and appetiteIvan De Araujo Icahn School of Medicine at Mount Sinai USAAVAILABLE ON DEMAND AFTER LIVE STREAM 19 30 19 45Novel candidate human obesity genes act in neurons to regulate adiposityNeha Agrawal University of Cambridge and University of Edinburgh UKAVAILABLE ON DEMAND AFTER LIVE STREAM 19 45 20 10NeuroimmunometabolismAna Domingos University of Oxford UK ONLY AVAILABLE TO VIEW LIVE 20 10 20 25Break20 25 20 50How the brain lungs and bladder contribute to social behavior in the mouseLisa Stowers Scripps Research USA AVAILABLE ON DEMAND AFTER LIVE STREAM 20 50 21 05Hormonal remodelling of a parenting circuit during pregnancyJohannes Kohl The Francis Crick Institute UKAVAILABLE ON DEMAND AFTER LIVE STREAM 21 05 21 20A hypothalamic plasticity mechanism for heat acclimationJan Siemens Heidelberg University GermanyAVAILABLE ON DEMAND AFTER LIVE STREAM 21 20 21 25 Transition to Panel Discussion 21 25 21 55Panel Discussion Session 2Chairs Ralph DeBerardinis and Ivan De Araujo ONLY AVAILABLE TO VIEW LIVE 21 55 22 00Transition to Bar Mixer22 00 22 30Social Programme Bar Mixer Day 2 Tuesday 22 March 2022 TimeSpeaker 13 00 13 45Social Programme Speed Networking14 00 17 00Session 3 Immune metabolic crosstalk Chairs Asya Rolls and Miguel Soares14 00 14 25Type 3 innate lymphoid cells as integrators of microbiota and gut neuroimmune interactionsDan Littman New York University USA AVAILABLE ON DEMAND AFTER LIVE STREAM 14 25 14 40A Drosophila tumor necrosis factor receptor TNFR restricts cytoplasmic TRAF levels to control gut metabolism immunity and tissue homeostasisDitte Andersen University of Copenhagen Denmark AVAILABLE ON DEMAND AFTER LIVE STREAM 14 40 15 05Remembering immunity immune representation in the insular cortexAsya Rolls Technion Israel Institute of Technology Israel AVAILABLE ON DEMAND AFTER LIVE STREAM 15 05 15 20 Break15 20 15 45Metabolic reprogramming a defense strategy against infectionMiguel Soares Instituto Gulbenkian de Ci ncia Portugal AVAILABLE ON DEMAND AFTER LIVE STREAM 15 45 16 00Neural control of macrophage activation regulates cardiac regenerationOnur Apaydin Max Delbr ck Center for Molecular Medicine GermanyONLY AVAILABLE TO VIEW LIVE 16 00 16 25Lifestyle and leukocyte dynamicsFilip Swirski Icahn School of Medicine at Mount Sinai USA ONLY AVAILABLE TO VIEW LIVE16 25 16 30Transition to Panel Discussion16 30 17 00Panel Discussion Session 3Chairs Asya Rolls and Miguel Soares ONLY AVAILABLE TO VIEW LIVE 17 00 17 30Break17 30 18 30Poster Session 2 P Z 18 30 18 35 Transition to Session 418 35 20 50Session 4 The gut and its microbes Chairs Ana Domingos and Henrique Veiga Fernandes 18 35 19 00Inter organ signalling the third dimensionIrene Miguel Aliaga MRC London Institute of Medical Sciences and Imperial College London UK ONLY AVAILABLE TO VIEW LIVE19 00 19 15A gut taste axis control sweet perception in DrosophilaMattias Alenius Ume University SwedenAVAILABLE ON DEMAND AFTER LIVE STREAM 19 15 19 40Neuronal regulation of immune fitnessHenrique Veiga Fernandes Champalimaud Foundation Portugal AVAILABLE ON DEMAND AFTER LIVE STREAM 19 40 19 55Break19 55 20 10Microbial influence on linear growth promotionFran ois Leulier Ecole Normale Sup rieure de Lyon CNRS France AVAILABLE ON DEMAND AFTER LIVE STREAM 20 10 20 25Enterohepatic cooperation during the postnatal establishment of immune homeostasisAnnika Schwentker University Hospital RWTH Aachen GermanyAVAILABLE ON DEMAND AFTER LIVE STREAM 20 25 20 50The impact of the skeleton on homeostasisGerard Karsenty Columbia University USA AVAILABLE ON DEMAND AFTER LIVE STREAM 20 50 20 55 Transition to Panel Discussion 20 55 21 25Panel Discussion Session 4Chairs Ana Domingos and Henrique Veiga Fernandes ONLY AVAILABLE TO VIEW LIVE 21 25 21 30Transition to Living Room Concert21 30 22 00Living Room Concert with Lazy Fur Day 3 Wednesday 23 March 2022 TimeSpeaker13 00 13 30Meet the Editors sessionwith Paraminder Dhillon FEBS Mari Carmen Fernandez Aguera Cell Metabolism Masha Gelfand Developmental Cell Deniz Senyilmaz Tiebe EMBO Yang Yang Cell13 30 14 00Break14 00 15 50Session 5 Fat and liver signals Chairs Gerard Karsenty and Pierre Leopold14 00 14 25The role of brown fat beyond thermogenesis how do brown fat and liver communicate Shingo Kajimura Harvard Medical School and Beth Israel Deaconess Medical Center USA AVAILABLE ON DEMAND AFTER LIVE STREAM 14 25 14 40Proteomics of protein trafficking by in vivo tissue specific labelingIlia Droujinine Scripps Research USA AVAILABLE ON DEMAND AFTER LIVE STREAM 14 40 14 55A mammalian system for in vivo discovery of organ secretome using proximity labellingRui Yang University of Southern California USAAVAILABLE ON DEMAND AFTER LIVE STREAM 14 55 15 10Break15 10 15 35Pathological disruption of hormonal and nutrient balance in tumor induced cachexiaPierre Leopold Institut Curie France ONLY AVAILABLE TO VIEW LIVE 15 35 15 50Reciprocal perfusion and organotypic microenvironments allow improved microphysiological systems and 3D tissue model crosstalkJoanne Shen Karolinska Institutet Sweden AVAILABLE ON DEMAND AFTER LIVE STREAM 15 50 16 50Evolutionary perspective on physiological controlKeynote Speaker Ruslan Medzhitov Yale School of Medicine USAAVAILABLE ON DEMAND AFTER LIVE STREAM 16 50 17 00 Break17 00 17 30Panel Discussion Session 5 and KeynoteChairs Gerard Karsenty and Pierre Leopold ONLY AVAILABLE TO VIEW LIVE 17 30 17 45Closing Remarks and Poster PrizeONLY AVAILABLE TO VIEW LIVE 17 45End of conference Practical Information Registration Fees and Abstract Submission Registration Fees include access to all of the talks digital poster sessions and online group discussions and help us cover our costs to run the event For further information please refer to the FAQ page PhD Student 140 Academia 190Industry 240 Accredited journalists may be eligible to register for a reduced press rate or in some cases for complimentary registration Registrants may be required to provide accreditation or equivalent proof of press membership after registration Please contact Nathalie Sneider for more information Confirmation and Payment Registration will be on a first come first served basis Your place can only be confirmed after payment of the registration fee I Types of payments accepted are international bank transfers and credit card payments Abstract submission Abstract submission deadline Monday 24 January 2022 Only registered participants are eligible to submit an abstract We only accept online abstract submissions After you have logged in and successfully registered you will receive an email asking you to submit your abstract Click on the link provided and enter your abstract in the text box provided Alternatively you can submit your abstract by clicking on the link on the confirmation page directly after registering The same login credentials are used for both processes When submitting your abstract you can also apply for an oral or poster presentation A selection process will take place with the results announced 2 3 weeks after the abstract submission deadline Please note Title The title should not exceed 20 words Only the first word of the title should start with a capital letter and the rest of the title should be in lowercase Authors and Affiliations Please fill in the author s details as requested in the online form The compulsory details are First Name Last Name Organisation Name Affiliation or Company Country and Email Mark only one author as the role of First author and please don t forget to indicate who will be presenting The order of the authors will be listed as follows First Author Co First Author alphabetically if multiple co author s in the order added by the submitter Presentation Types When submitting your abstract you can apply for an oral or poster presentation A selection process will take place with the results announced 2 3 weeks after the abstract submission deadline Please check our FAQs pages for further information on how to submit an abstract Financial Assistance Financial Assistance Registration Fee Waiver All academic and student registrants are invited to apply for a registration fee waiver provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO The registration fee waiver covers the registration sum that you have paid to attend the meeting Conference participants are not required to pre pay the registration fee to be selected for a fee waiver for a virtual meeting If you have already paid the registration fee and are awarded a fee waiver it will be reimbursed after the meeting The fee waiver will cover the registration sum that you have paid to attend the course or conference Childcare Grant For participants and speakers with childcare responsibilities there is the possibility to apply for a grant provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO to offset childcare costs incurred when participating at a virtual event Eligible costs include fees for a babysitter or childcare facility or travel costs for a care giver Please note that priority will be given to early stage researchers Costs will be reimbursed after the meeting only once a reimbursement form and original receipts have been received Attendance at the event is required in order to be eligible to receive the reimbursement In order to apply for this grant you must be registered by the abstract submission deadline Application Applications for financial assistance can be submitted via the submission portal for the submission of abstracts for conferences by completing the Financial Assistance Application Section underneath the section for entering abstract motivation letter information The link to the portal can be found in the registration confirmation email that you will receive after registering for the conference For conferences if you are not submitting an abstract you can still apply for financial assistance in the submission portal Take a look at the instructions for applying for financial assistance Note that priority will be given to those submitting an abstract to present at the conference In your application you will be asked to answer questions regarding your motivation for applying and for registration fee waivers the reasons why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Selection The scientific organisers will select the recipients of all financial assistance during the motivation letter or abstract selection process Results will be announced approximately around 5 weeks before the event start date however for some events this may be delayed Selection results do not impact your admission to the meeting Selection is based on your current work or study location the reasons for needing financial support and the impact this event will have on your career Further details See our list of external funding opportunities and information on attending a conference as an event reporter For further information about financial assistance please refer to the FAQ page Virtual Participation Guidelines Do not broadcast the conference to unregistered participants You are encouraged to tweet and post about the event Tweet unless the speaker specifically says otherwise but be mindful of unpublished data Please do not capture transmit or redistribute data presented at the meeting Additional information can be found in our Code of Conduct Health and well being It is important to stay healthy and move around especially when you are attending an event virtually We have put together a few coffee break stretches and yoga videos in the conference platform for you to enjoy during the event How to ask questions Please use the Q A function in the event platform If you have any other questions you can go to the Help Desk in the event platform Click on more on the top menu and click Help Desk Time zone The programme is planned based on the Europe Berlin time zone unless otherwise stated As many virtual participants are attending from around the world we do our best to accommodate as many time zones as possible when creating the programme Please take your time zone into consideration when planning your attendance Remember to set your time zone in your account Virtual event platforms We are using a virtual event platform for this conference More information about the platform will be shared ahead of the conference Additional Information Please find additional information including FAQs and terms and conditions on our Information for Participants page Sponsors Media partners Development a The Company of Biologists journal Disease Models Mechanisms The Company of Biologists Journal EMBO Journal an EMBO Press journal International Union of Biochemistry and Molecular Biology Open Biology a Royal Society journal Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a Sponsorship Brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsoring embl de About EMBO EMBL Symposia promote scientific communication and collaboration in the European research area They provide scientists with a platform to discuss and exchange ideas on forward looking topics and new developments in the life sciences Topics emphasise upcoming developments and the interdisciplinary nature of related fields Jointly funded and organised by EMBO and EMBL and complementary to their respective courses workshops and conference programmes the symposia promote scientific communication and collaboration All symposia are held in the EMBL Advanced Training Centre ATC in Heidelberg Germany or virtually...

Gerard Karsenty, Irene Miguel-Aliaga, Miguel Soares

EMBO | EMBL Symposium

Virtual

16 March 2022

Discovering biological information from mass spectrometry-based proteomics

Edit

March 16, 2022 15:302022WebinarVirtual

Description Mass spectrometry based proteomics has revolutionised the analysis of proteins by enabling quantitative analysis of thousands of proteins and their properties including post translational modification PTM The resulting datasets are rich multidimensional and comprehensive The webinar will cover basics of peptide and PTM identification by mass spectrometry strategies for quantitation and introduce tools for the analysis of proteomic datasets...

Tony Ly

Virtual

15 March 2022

Programming skills in biocuration

Edit

March 15, 2022 15:302022WebinarVirtual

Description This webinar will be the first of our series of webinars on the topic of biocuration and discuss programming skills that can be beneficial in biocuration as well as provide advice on how to acquire them In an ELIXIR survey in 2019 which aimed at identifying training needs in biocuration the most commonly indicated ones were programming scripting coding development and use of ontologies and database management In addition skills like programming and extracting data from literature were mentioned as decisive for a successful biocuration career With our webinar series we want to help to close this gap Biocurators from different backgrounds and institutes will share their experience on how they have acquired these relevant skills in their job how they apply these in their works and why they benefit from it The speakers will also point to helpful tools and resources they use In this first webinar we will hear from two UniProt biocurators who will share their experience on how they acquired programming skills and show you some intuitive scripts in Python and SQL which they use to facilitate some of their curation tasks In addition we will introduce other helpful curation software like UniFire a functional protein annotation system Speakers Elena Speretta EMBL EBI Elena Speretta is a Biocurator in the Protein Function Content team of UniProt at EMBL EBI working on the curation of Drosophila proteins as well as the creation of rules for automatic annotation of protein function Prior to joining EMBL EBI she worked as a postdoctoral researcher at the University of Dundee UK She obtained her PhD from the University of Cambridge UK and undergraduate degree from the University of Trieste Italy Pedro Raposo EMBL EBI Pedro Raposo is a Bioinformatician in the Protein Function Content team of UniProt at EMBL EBI working on creation of rules for automatic annotation of protein function After obtaining his MSc in Bioinformatics he worked at the UK Stem Cell Bank on genomic data before joining EMBL EBI...

Elena Speretta, Pedro Raposo

Virtual

15 March 2022

Edit

March 09, 2022 15:302022WebinarVirtual

Description Newly sequenced genomes including those produced by the Darwin Tree of Life project are all added to Ensembl Rapid Release These genomes have minimal annotation with genes mapped onto the genome protein domain analysis and homologue predictions This webinar will guide you through the data available for newly annotated species in the Ensembl Rapid Release site and how to cross reference against more fully annotated genomes in the main Ensembl genome browser...

Benjamin Moore

Virtual

8 March - 10 March 2022

Ensembl Browser Virtual Workshop, March 2022

Edit

March 08, 2022 00:002022CourseVirtual

Description Work with the Ensembl Outreach team to get to grips with the Ensembl browser accessing gene variation comparative genomics and regulation data and mine these data with BioMart...

Aleena Mushtaq

Virtual

7 March - 11 March 2022

Edit

February 14, 2022 00:002022CourseVirtual

Description Work with the Ensembl Outreach team to get to grips with the Ensembl browser accessing gene variation comparative genomics and regulation data and mine these data with BioMart...

Aleena Mushtaq

Virtual

14 February - 18 February 2022

CABANA Workshop: Bioinformatics approaches to viruses and genomic surveillance

Edit

February 14, 2022 00:002022CourseVirtual

Juanita Riveros

Virtual

9 February 2022

Exploring genotype-phenotype data using the GWAS Catalog

Edit

February 09, 2022 15:302022WebinarVirtual

Description The GWAS Catalog is the primary resource of genotype phenotype associations identified through genome wide association studies GWAS Catalog data are publicly available in a consistent searchable and visualisable format which is easily integrated with other resources Uses for the data include prioritising candidate loci exploring disease mechanisms predicting risk of disease identifying new drug targets gathering statistics on traits or populations of interest and downloading full summary data for use in downstream analyses This webinar will include a brief introduction to the GWAS Catalog and a demonstration of our web based search interface focusing on the most common use cases...

Maria Cerezo

Virtual

9 February - 11 February 2022

The epitranscriptome

Edit

Edit

January 26, 2022 00:002022ConferenceVirtual

Description OverviewOrganisers and SpeakersParticipating OrganisationsProgrammePractical InformationSponsors Overview Conference Overview Infectious diseases are among the most prevalent causes of human illness and death in the world Pathogens infect humans and all life forms on Earth being able to cross species barriers thereby adversely impacting human and planetary health Fundamental research in Infection Biology is urgently needed to find therapies for longstanding and emerging infectious diseases The EMBL Conference The Next Generation in Infection Biology is a platform for late stage postdoctoral scientists in the field of infection biology to present their work and connect with the leading European institutions in infection biology The speakers will be chosen for their track record of research accomplishments and their high reaching future plans The audience will have the unique opportunity to experience cutting edge science presented by the rising leaders in this field The institutional partners will provide discussion and networking opportunities to connect and shape the future league of infection biologists in Europe Session Topics Anti infectives vaccines antimicrobials Host pathogen interfacesHost genetics and immunologyPathogen Biology Organisers and Speakers Plenary Speakers Pascale Cossart Institut Pasteur France David Holden Imperial College London UK Scientific Organisers Pedro Beltrao EMBL EBI Hinxton UK Maria Bernabeu EMBL Barcelona Spain Jan Kosinski EMBL Hamburg Germany Eva Kowalinski EMBL Grenoble France Nassos Typas EMBL Heidelberg Germany Conference Organiser Inna Boesselmann EMBL Heidelberg Germany Raili Pall EMBL Heidelberg Germany Nathalie Sneider EMBL Heidelberg Germany Participating Organisations Please find below a list of participating institutes and universities with more to be confirmed in the coming weeks Institutes UniversitiesCountrySpokespersonAix Marseille University CNRS Institut de Microbiologie de la M diterran e IMM FranceT m MignotAPC Microbiome Ireland University College of CorkIrelandColin HillBiozentrum University of Basel SwitzerlandUrs Jenal Center for Integrative Infectious Disease Research CIID Heidelberg UniversityGermanyFriedrich Frischknecht Hans Georg Kr usslichCenter of Excellence for Virus Immunology and Vaccines CERVirVac CroatiaStipan Jonji CSIC CNB National Centre for Biotechnology SpainDaniel Lopezde Duve Institute Universit Catholique de LouvainBelgiumJean Fran ois ColletDTU BioengineeringDenmarkLars JelsbakEMBLGermany France Spain UKScientific OrganisersEMBL AustraliaAustraliaDavid LynnGlobal Health Institute EPFLSwitzerlandBruno LemaitreHelmholtz Centre for Infection Research HZI GermanyDirk HeinzHubrecht InstituteNetherlandsJeroen den HertogMarvin TanenbaumHuman TechnopoleItalyFernanda PinheiroImperial College London The MRC Center for Molecular Bacteriology InfectionUKJos PenadesInstitut PasteurFranceMarc LecuitInstitute Gulbenkian de Ci ncia IGC PortugalKarina XavierInstitute of Microbiology ETH ZurichSwitzerlandWolf Dietrich HardtInstitute of Molecular Biology and Biotechnology of the Foundation for Research and Technology Hellas IMBB FORTH GreeceGeorgios ChamilosInstitute of Technology University of TartuEstoniaTanel TensonInstituto de Medicina Molecular iMM PortugalMaria MotaInternational Institute of Molecular and Cell Biology in Warsaw IIMCB PolandGracjan MichlewskiKarolinska InstitutetSwedenBirgitta Henriques Normark Edmund LohLCSB Luxembourg Centre for Systems Biomedicine University of LuxembourgLuxembourgPaul WilmesMax Perutz LabsAustriaPavel KovarikNCCR AntiResistSwitzerlandChristoph DehioTampere University of Applied Sciences TAMK Tampere UniversityFinlandMataleena ParikkaThe Francis Crick InstituteUKDavid BauerThe Laboratory for Molecular Infection Medicine Sweden MIMS Ume UniversitySwedenOliver Billker UiT The Arctic University of Norway Center for New Antibacterial Strategies CANS NorwayP l Jarle JohnsenUMC Utrecht Infection ImmunityThe NetherlandsSuzan RooijakkersUniversity College DublinIrelandStephen GordonUniversity of MaltaMaltaJoseph BorgUniversity of ToulouseFranceJerome NigouYoann RomboutsVIBBelgiumCharles Van de Henst Jan MichielsWeizmann Institute of ScienceIsraelEran Elinav Programme Got something to say Tweet it EMBLInfectionBiology All talks will be live streamed with Q A Networking Sessions will be held with participating organizations at the end of each session Information on the live stream and access to the discussion platform and video library will be provided shortly before the start of the event Access to the recorded talks will be available for 3 weeks after the start of the event All times in the programme below are shown as the time in Europe Berlin Amsterdam Paris To find out the equivalent time zone in your location enter Berlin the programme time and date along with your city into the Time Zone Converter Day 1 Wednesday 26 January 2022 TimeSpeaker13 20 13 40 Opening remarks by Scientific Organisers introduction remarks by Edith Heard AVAILABLE ON DEMAND AFTER LIVE STREAM13 40 14 20Plenary talk The chance and the pleasure to promote an emerging disciplinePascale Cossart Institut Pasteur FranceAVAILABLE ON DEMAND AFTER LIVE STREAM 14 20 14 25Session 1 Pathogen BiologyChairs Jan Kosinski EMBL Hamburg Germany Eva Kowalinski EMBL Grenoble France14 25 14 45Structural studies on the evolution of SARS CoV 2 spikeAntoni Wrobel The Francis Crick Institute UKAVAILABLE ON DEMAND AFTER LIVE STREAM 14 45 15 05Exploiting N glycosylation against COVID 19Aitor Casas Sanchez Liverpool School of Tropical Medicine UKAVAILABLE ON DEMAND AFTER LIVE STREAM 15 05 15 25Aspergillus fumigatus pan genome analysis identifies genetic variants associated with human infectionAmelia Barber Leibniz HKI GermanyAVAILABLE ON DEMAND AFTER LIVE STREAM 15 25 15 45Mechanistic Elucidation of A Novel Anti jumbophage Immune SystemYuping Li University of California San Francisco USAAVAILABLE ON DEMAND AFTER LIVE STREAM 15 45 16 05Break16 05 17 05Networking Session 1 with Institute Spokesperson in breakout rooms LIVE STREAM ONLY 17 05 17 10Session 2 Host pathogen InterfacesChairs Pedro Beltrao EMBL EBI Hinxton UK Maria Bernabeu EMBL Barcelona Spain17 10 17 30How S acylation controls SARS CoV 2 infectionFrancisco Mesquita EPFL Switzerland AVAILABLE ON DEMAND AFTER LIVE STREAM 17 30 17 50Functional single cell genomics of virus host systemsMarco Hein USCF USA AVAILABLE ON DEMAND AFTER LIVE STREAM 17 50 18 10Breaking and entering the voyage of Trypanosoma brucei across host barriers biophysical properties of host pathogen interactionsMariana De Niz Institut Pasteur France AVAILABLE ON DEMAND AFTER LIVE STREAM 18 10 18 30In situ structures of membrane assisted assembly and selective autophagy of enterovirusesSelma Dahmane Ume University Sweden AVAILABLE ON DEMAND AFTER LIVE STREAM 18 30 18 50Break 18 50 19 50Networking Session 2 with Institute Spokesperson in breakout roomsLIVE STREAM ONLY End of day 1 Continued access to networking and discussion platforms Day 2 Thursday 27 January 2022 TimeSpeaker11 00 12 15Career panel discussion Preparing for an academic interview Speakers Joseph Borg University of Malta MaltaDaniel Lopez CSIC CNB Spain T m Mignot CNRS IMM FranceSuzan Rooijakkers UMC Utrecht Infection Immunity The NetherlandsModerators Rachel Graf and Patricia Cabezas EMBL Heidelberg Germany12 15 13 30Break13 30 13 40 Introduction remarks by Nassos Typas Nassos Typas EMBL Heidelberg Germany 13 40 14 20Why failure in science is underratedPlenary talk David Holden Imperial College London UK AVAILABLE ON DEMAND AFTER LIVE STREAM 14 20 14 25Session 3 Host genetics and immunologyChairs Pascale Cossart Institut Pasteur France Suzan Rooijakkers UMC Utrecht Infection Immunity The Netherlands 14 25 14 45Acute liver failure is regulated by MYC and microbiome dependent programsAleksandra Kolodziejczyk Weizmann Institute of Science Israel AVAILABLE ON DEMAND AFTER LIVE STREAM 14 45 15 05Deciphering nasal chromatin immunoregulation to commensals vs pathogensMichael Connor Institut Pasteur France AVAILABLE ON DEMAND AFTER LIVE STREAM 15 05 15 25Bacterial gasdermins reveal conservation of immune mechanisms from bacteria to humanTanita Wein Weizmann Institute of Science Israel AVAILABLE ON DEMAND AFTER LIVE STREAM 15 25 15 45Mechanistic investigations of adenovirus and mRNA vaccine immunogenicityNicholas Provine University of Oxford UK AVAILABLE ON DEMAND AFTER LIVE STREAM 15 45 16 05Break16 05 17 05Networking Session 3 with Institute Spokesperson in breakout rooms LIVE STREAM ONLY 17 05 17 10Session 4 Anti infectives vaccines antimicrobials Chairs Fernanda Pinheiro Human Technopole Italy Nassos Typas EMBL Heidelberg Germany17 10 17 30Unravelling the collateral damage of antibiotics on gut bacteriaCamille Goemans EMBL Heidelberg Germany AVAILABLE ON DEMAND AFTER LIVE STREAM 17 30 17 50Listen to our viral friends exploring bacteriophage diversity to learn new tricks for clinics and biotechnologyAlexander Harms University of Basel SwitzerlandLIVE STREAM ONLY17 50 18 10Superbug kryptonite A potential immunotherapeutic for the next generation of antibioticsJennifer Payne Monash University Australiapre recorded talk18 10 18 30Broad beta coronavirus neutralization by stem helix specific human antibodiesMaximilian Sauer University of Washington USA AVAILABLE ON DEMAND AFTER LIVE STREAM 18 30 18 50Break Transition18 50 19 50Networking Session 4 with Institute Spokesperson in breakout roomsLIVE STREAM ONLY 19 50 20 00Closing remarksLIVE STREAM ONLY Practical Information Registration Fees and Abstract Submission Registration Fees include access to all of the talks digital poster sessions and online group discussions and help us cover our costs to run the event For further information please refer to the FAQ page PhD Student Postdoc140 EuroAcademia PI190 EuroIndustry240 EuroEMBL StaffIntranet access Accredited journalists may be eligible to register for complimentary registration Registrants may be required to provide accreditation or equivalent proof of press membership after registration Please contact Inna B sselmann for more information Confirmation and Payment Registration will be on a first come first served basis Your place can only be confirmed after payment of the registration fee Types of payments accepted are international bank transfers and credit card payments Abstract Submission Instructions for Postdocs wishing to apply for an oral presentation Only registered participants are eligible to submit an abstract We only accept online abstract submissions After you have logged in and successfully registered you will receive an email asking you to submit your abstract of your current work general directions of your future lab specific aims of your research plan and include a brief CV with three selected publications Additionally you will be asked to submit a 5 minutes video short talk Click on the link provided and enter your application details Alternatively you can submit your abstract by clicking on the link on the confirmation page directly after registering Your application will only be complete when both abstract and short talk video have been submitted Plenary talks will be selected from the applications based on all submitted material The submitted application material will be accessible to all participants throughout the conference A selection process will take place with the results announced 5 6 weeks after the abstract submission deadline For infection biology institutes wishing to participate please contact the organisers Financial Assistance Registration Fee Waivers All academic and student registrants are invited to apply for a registration fee waiver provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO The registration fee waiver covers the registration sum that you have paid to attend the meeting Conference participants are not required to pre pay the registration fee to be selected for a fee waiver for a virtual meeting If you have already paid the registration fee and are awarded a fee waiver it will be reimbursed after the meeting Application Applications for financial assistance can be submitted via the submission portal for the submission of abstracts for conferences or the submission of motivation letters for courses by completing the Financial Assistance Application Section underneath the section for entering abstract motivation letter information The link to the portal can be found in the registration confirmation email that you will receive after registering for the conference Selection The scientific organisers will select the recipients of registration fee waivers during the abstract selection process for conferences and the participant selection process for courses Results will be announced approximately 3 4 weeks before the event start date Selection results do not impact your admission to the meeting Registration fee waiver selection is based on your current work or study location your motivation for applying the reasons for needing financial support and the impact this event will have on your career Further details Check our list of external funding opportunities and information on attending a conference as an event reporter For further information about financial assistance please refer to the FAQ page Virtual Participation Guidelines Guidelines Please do Use the event specific hashtag as communicated during the event for any related tweetsTweet unless the speaker specifically says otherwiseBe mindful of unpublished dataBe respectful in tone and content Please don t Share Slack live stream or poster session links with othersBroadcast the conference to unregistered participantsCapture transmit or redistribute data presented at the meeting unless presenter gives explicit consentUse offensive language in your postsEngage in rudeness or personal attacks Additional information can be found in our Code of Conduct Health and well being It is important to stay healthy and move around especially when you are attending an event virtually We have put together a few coffee break stretches and yoga videos You can find these under resources on the conference platform How to ask questions Please use the Q A function It is possible to send a direct message to participants poster presenters and speakers within the conference platform If you have any other questions you can go to the Help Desk on the conference platform Click on more on the top menu and click Help Desk Time zone The programme is planned based on Central European Time CET or Central European Summer Time CEST unless otherwise stated As many virtual participants are attending from around the world we do our best to accommodate as many time zones as possible when creating the programme Please take your time zone into consideration when planning your attendance Remember to set your time zone in your account Virtual event platforms We are using a virtual event platform for this conference More information about the platform will be shared ahead of the conference Additional Information Please find additional information including FAQs and terms and conditions on our Information for Participants page Sponsors Media partners Disease Models Mechanisms The Company of Biologists Journal EMBO Journal an EMBO Press journal International Union of Biochemistry and Molecular Biology Open Biology a Royal Society journal Sponsorship opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a Sponsorship Brochure...

Pedro Beltrao, Maria Bernabeu, Jan Kosinski, Eva Kowalinski, Nassos Typas

EMBL Conference

Virtual

20 January 2022

Uncovering protein function with UniProt

Edit

January 20, 2022 15:002022WebinarVirtual

Description This webinar will discuss what functional information is available in UniProt and where that information comes from It will also describe how the information is added to the resource and how to find it on the UniProt website...

Michele Magrane

Virtual

20 January 2022

Analysing publications and funding with the Europe PMC REST API

Edit

November 24, 2021 15:302021WebinarVirtual

Description Europe PMC is a database of life science publications and preprints Articles in Europe PMC are enriched with additional resources such as author funding and affiliation information citations and links to data peer reviews and more In this webinar we will explain how to programmatically access publications and related information using the Europe PMC Articles RESTful API Michael Parkin Data Scientist at Europe PMC will demonstrate how to access the API using the browser and provide some scripting examples in Python R He will outline different API methods rules for filtering and pagination as well as output formats Following on Antonio Campello Senior Data Scientist at the Wellcome Trust will explain how Wellcome uses Europe PMC APIs to gain insights into the outputs of the research they fund He will discuss several use cases including charting Wellcome s research portfolio developing novel technologies to link grants to academic publications and tracking which grants have been influential to the COVID 19 literature Additional reading Linking academic publications to grants with machine learning Which research fields have emerged in the last years A machine learning approach...

Michael Parkin, Antonio Campello

Virtual

22 November - 24 November 2021

Cancer genomics

Edit

November 22, 2021 00:002021ConferenceVirtual

Description OverviewSpeakersProgrammePractical InformationSponsorsPre conference webinars Overview EMBL is committed to sharing research advances and sustaining scientific interaction throughout the coronavirus pandemic We are delighted to announce that this conference is going virtual and invite you to join us online Conference Overview This conference will provide an opportunity to learn about and keep up to date with the rapidly progressing area of cancer genomics It will cover presentations from cancer genome projects the areas of cancer functional genomics systems biology cancer immunogenomics and epigenomics cancer mouse models and the translation and clinical impact of obtained scientific results The meeting will bring together leading scientists from across these areas for a unique opportunity to interact and stimulate further integration of these efforts Session Topics Mutation and clonal selection in normal tissuesGenomic instability and mutational processesCancer evolution and driversEmerging technologies in cancer genomicsCancer ecosystems microenvironment and immunogenomicsCancer genome medicine What past participants say about the conference EMBL provided a wonderful opportunity for the exchange and application of new ideas within the OMICs cancer research A great conference Angelica Boldt Postgraduate Program in Genetics Department of Genetics Federal University of Paran UFPR Argentina This is the third time I have attended this conference I keep coming back because of the quality of work presented the expectation that presenters discuss their latest findings and the meeting having the optimal number of attendees Sean Grimmond University of Melbourne Australia Speakers Keynote Speaker Peter Campbell Wellcome Sanger Institute UK Speakers Hannah Carter University of California San Diego USA Edwin Cuppen UMC Utrecht The Netherlands Christina Curtis Stanford University USA Moritz Gerstung EMBL EBI Hinxton UK Holger Heyn Centre for Genomic Regulation CNAG CRG Spain Marcin Imieli ski Weill Cornell Medicine USA Nada Jabado McGill University Canada Jan Korbel EMBL Heidelberg Germany Dan Landau Weill Cornell Medical College USA Po Ru Loh Harvard Medical School USA N ria L pez Bigas Institute for Research in Biomedicine Spain Seishi Ogawa Kyoto University Japan Elli Papaemmanuil Memorial Sloan Kettering Cancer Center USA Raheleh Rahbari Wellcome Sanger Institute UK Toshiro Sato Keio University Japan Fran Supek Institute for Research in Biomedicine Spain Scientific Organisers Jan Korbel EMBL Heidelberg Germany N ria L pez Bigas Institute for Research in Biomedicine Spain Seishi Ogawa Kyoto University Japan Elli Papaemmanuil Memorial Sloan Kettering Cancer Center USA Conference Organiser Maryann Heck EMBL Heidelberg Germany Chris Stocks EMBL Heidelberg Germany Programme Got something to say Tweet it EMBLCanGen The virtual conference includes live streamed invited speaker talks and live streamed selected short talks with live Q A sessions after each talk as well as meet the speaker sessions All digital poster presenters are encouraged to upload a recorded flash talk or narration with their digital poster and to schedule video calls during poster session times Information on the live stream and access to the discussion platform and digital posters will be provided 1 week before the start of the event All times in the programme below are shown as the time in Europe Berlin To find out the equivalent time zone in your location enter Berlin the programme time and your city into the Time Zone Converter Day 1 Monday 22 November 2021 TimeSpeaker12 00 12 50Pre conference webinars Precision Medicine meets immuno oncology innovative biomarkers and beyond by Bristol Myers SquibbDNA methylation in biofluids from genome wide studies to targeted approaches by Diagenode abstracts are available in Pre conference webinars tab 13 00 13 50Pre conference webinars 3D Genome Analysis Identifies Therapeutic Targets in Pediatric Brain Cancer by Arima GenomicsStructural and functional heterogeneity in the spatial organization of glioblastoma patient genomes by Dovetail Genomics abstracts are available in Pre conference webinars tab 14 00 14 10Opening remarks14 10 15 25Session 1 Mutation and clonal selection in normal tissues14 10 14 40The mutational landscape and clonal dynamics of Human Somatic and Germline cellsRaheleh Rahbari Wellcome Sanger Institute UKAVAILABLE ON DEMAND AFTER LIVE STREAM 14 40 14 55Somatic Mutations in The Ageing BrainLuke Harvey Welcome Trust Sanger Institute UKAVAILABLE ON DEMAND AFTER LIVE STREAM 14 55 15 25Monogenic and polygenic inheritance become instruments for clonal selectionPo Ru Loh Harvard Medical School USAAVAILABLE ON DEMAND AFTER LIVE STREAM 15 25 15 40Break15 40 16 25Keynote Talk title to be announcedPeter Campbell Wellcome Sanger Institute UKAVAILABLE ON DEMAND AFTER LIVE STREAM 16 25 17 00Meet the speakers from Session 117 00 18 00Poster Session 1 live chats and video calls with poster presenters with last names A L 18 00 18 15Break18 15 20 15Session 2 Genomic instability and mutational processes18 15 18 45Patterns in local mutation density in cancer genomesFran Supek Institute for Research in Biomedicine SpainAVAILABLE ON DEMAND AFTER LIVE STREAM 18 45 19 00Re running cancer evolution in vivo a high resolution multi omics approachSarah Aitken University of Cambridge UKAVAILABLE ON DEMAND AFTER LIVE STREAM 19 00 19 30In silico saturation mutagenesis of cancer genesNuria Lopez Bigas Institute for Research in Biomedicine SpainAVAILABLE ON DEMAND AFTER LIVE STREAM 19 30 19 45Antiviral treatment causes a unique mutational signature in cancers of transplantation recipientsJurrian de Kanter Princess M xima Center for Pediatric Oncology The NetherlandsAVAILABLE ON DEMAND AFTER LIVE STREAM 19 45 20 15Haplotype aware single cell multiomics uncovers functional effects of somatic structural variationJan Korbel EMBL Heidelberg GermanyAVAILABLE ON DEMAND AFTER LIVE STREAM 20 15 20 25Break20 25 20 55Meet the speakers from Session 2 20 55 21 30Virtual Speed Networking Day 2 Tuesday 23 November 2021 Time Speaker13 30 13 50 Industry session 14 00 16 30Session 3 Cancer evolution and drivers14 00 14 30Molecular classification and risk stratification of colorectal cancerSeishi Ogawa Kyoto University Japan AVAILABLE ON DEMAND AFTER LIVE STREAM 14 30 14 45Discerning patterns of evolution during progression and metastatic spread in high risk neuroblastomaGunes Gundem Memorial Sloan Kettering Cancer Center USAAVAILABLE ON DEMAND AFTER LIVE STREAM 14 45 15 00ASCAT sc a generic framework for copy number callingMaxime Tarabichi Universit Libre de Bruxelles ULB BelgiumAVAILABLE ON DEMAND AFTER LIVE STREAM 15 00 15 30Genotype to phenotype mapping of tumorigenesis at single cell resolutionChristina Curtis Stanford University USALIVE STREAM ONLY 15 30 15 45Break15 45 16 15Stalled development through altered epigenetic states at the root of oncohistone pathogenicityNada Jabado McGill University CanadaAVAILABLE ON DEMAND AFTER LIVE STREAM 16 15 16 30Reconstructing Chromothriptic Chromosomes in Oesophageal AdenocarcinomasJannat Ijaz Wellcome Trust Sanger Institute UKAVAILABLE ON DEMAND AFTER LIVE STREAM 16 30 17 05Meet the speakers from Session 317 05 18 05Poster Session 2 live chats and video calls with poster presenters with last names M Z 18 05 18 20Break18 20 19 50Session 4 Emerging technologies in cancer genomics18 20 18 50Pathognomonic long molecule footprints of backup repair pathways in homologous recombination deficient cancersMarcin Imilienski Weill Cornell Medicine USA AVAILABLE ON DEMAND AFTER LIVE STREAM 18 50 19 05Exploiting immunity of hepatocellular carcinoma HCC to improve treatment of patientsDomitille Chalopin Fillot Universit de Bordeaux FranceAVAILABLE ON DEMAND AFTER LIVE STREAM 19 05 19 35Single cell and spatially resolved tumor immune microenvironmentsHolger Heyn Centre for Genomic Regulation CNAG CRG SpainAVAILABLE ON DEMAND AFTER LIVE STREAM 19 35 19 50Modeling human clonal hematopoiesis in vitroFranziska Briest Universit ts Medizin Berlin GermanyLIVE STREAM ONLY19 50 20 00Break20 00 20 30Meet the speakers from Session 420 30 21 30Bar Mixer Day 3 Wednesday 24 November 2021 TimeSpeaker14 00 16 30Session 5 Cancer ecosystems microenvironment and immunogenomics14 00 14 30Understanding of cancer genotype phenotype association using organoid technologyToshiro Sato Keio University Japan AVAILABLE ON DEMAND AFTER LIVE STREAM 14 30 14 45The relationship of germline risk to somatic EGFR mutation in lung cancerMatthew Meyerson Dana Farber Cancer Institute USAAVAILABLE ON DEMAND AFTER LIVE STREAM 14 45 15 00The impact and prevalence of genetic immune escape in primary and metastatic cancerFrancisco Mart nez Jim nez UMC Utrecht The NetherlandsAVAILABLE ON DEMAND AFTER LIVE STREAM 15 00 15 30Epigenetic encoding heritability and plasticity of glioma transcriptional cell statesDan Landau Weill Cornell Medical College USAAVAILABLE ON DEMAND AFTER LIVE STREAM 15 30 15 45Break15 45 16 15Germline immune variants influence tumor immunotherapy outcomesHannah Carter University of California San Diego USAAVAILABLE ON DEMAND AFTER LIVE STREAM16 15 16 30The somatic mutational landscape of normal tissues in chemotherapy treated cancer patientsEllie Dunstone Sanger Institute UKAVAILABLE ON DEMAND AFTER LIVE STREAM 16 30 17 05Meet the speakers from Session 517 05 17 20Break17 20 19 20Session 6 Cancer genome medicine17 20 17 50Talk title to be announcedElli Papaemanouil Memorial Sloan Kettering Cancer Center USALIVE STREAM ONLY 17 50 18 05A clinical molecular and personalized risk scoring system for patients with myelodysplastic syndromesElsa Bernard Memorial Sloan Kettering Cancer Center USAAVAILABLE ON DEMAND AFTER LIVE STREAM 18 05 18 35Spatial genomics maps the structure character and evolution of cancer clonesMoritz Gerstung EMBL EBI Hinxton UKAVAILABLE ON DEMAND AFTER LIVE STREAM 18 35 18 50Mutagenic effects of chemotherapy in secondary malignancies and normal cells in pediatric cancer patientsAxel Rosendahl Huber Princess M xima Center for Pediatric Oncology and Oncode Institute The NetherlandsAVAILABLE ON DEMAND AFTER LIVE STREAM 18 50 19 20Understanding mutational landscapes in metastatic cancerEdwin Cuppen UMC Utrecht The NetherlandsAVAILABLE ON DEMAND AFTER LIVE STREAM 19 20 19 30Closing remarks19 30 20 00Meet the speakers from Session 6 Practical Information Registration Fees and Abstract Submission Registration Fees include access to all of the talks digital poster sessions and online group discussions and help us cover our costs to run the event For further information please refer to the FAQ page Academia190 EuroPhD Student140 EuroIndustry240 EuroEMBL StaffIntranet access Accredited journalists may be eligible to register for a complimentary registration Registrants may be required to provide accreditation or equivalent proof of press membership after registration Please contact Maryann Heck for more information Confirmation and Payment Registration will be on a first come first served basis Your place can only be confirmed after payment of the registration fee Types of payments accepted are international bank transfers and credit card payments Abstract submission Only registered participants are eligible to submit an abstract We only accept online abstract submissions After you have logged in and successfully registered you will receive an email asking you to submit your abstract Click on the link provided and enter your abstract in the text box provided Alternatively you can submit your abstract by clicking on the link on the confirmation page directly after registering When submitting your abstract you can also apply for an oral or poster presentation A selection process will take place with the results announced 2 3 weeks after the abstract submission deadline Financial Assistance Financial Assistance Registration Fee Waivers All academic and student registrants are invited to apply for a registration fee waiver provided by the EMBL Advanced Training Centre Corporate Partnership Programme The registration fee waiver covers the registration sum that you have paid to attend the meeting Conference participants are not required to pre pay the registration fee to be selected for a fee waiver for a virtual meeting If you have already paid the registration fee and are awarded a fee waiver it will be reimbursed after the meeting Course participants are required to pay the course fee in advance which will then be reimbursed after the recipient has attended the course Childcare Grants For participants and speakers with childcare responsibilities there is the possibility to apply for a grant provided by the EMBL Advanced Training Centre Corporate Partnership Programme to offset childcare costs incurred when participating at a virtual event Eligible costs include fees for a babysitter or childcare facility or travel costs for a care giver Please note that priority will be given to early stage researchers Costs will be reimbursed after the meeting only once a reimbursement form and original receipts have been received Attendance at the event is required in order to be eligible to receive the reimbursement In order to apply for this grant you must be registered by the abstract submission deadline Application Applications for financial assistance can be submitted via the submission portal for the submission of abstracts for conferences or the submission of motivation letters for courses by completing the Financial Assistance Application Section underneath the section for entering abstract motivation letter information The link to the portal can be found in the registration confirmation email that you will receive after registering for the conference or course For conferences if you are not submitting an abstract you can still apply for financial assistance in the submission portal Take a look at the instructions for applying for financial assistance Note that priority will be given to those submitting an abstract to present at the conference In your application you will be asked to answer questions regarding your motivation for applying and for registration fee waivers the reasons why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application For some events applications for Childcare Grants will still be done by email Information about the grant will be sent out shortly after the abstract motivation letter deadline Please contact the event Conference Officer if you have any questions Selection The scientific organisers will select the recipients of registration fee waivers during the abstract selection process for conferences and the participant selection process for courses Results will be announced approximately 3 4 weeks before the event start date Selection results do not impact your admission to the meeting Registration fee waiver selection is based on your current work or study location your motivation for applying the reasons for needing financial support and the impact this event will have on your career Childcare grants are allocated based on career stage with priority given to early stage researchers Further details A list of external funding opportunities can be found here and information on attending a conference as an event reporter here For further information about financial assistance please refer to the FAQ page Virtual Participation Guidelines Guidelines Please do Use the event specific hashtag as communicated during the event for any related tweetsTweet unless the speaker specifically says otherwiseBe mindful of unpublished dataBe respectful in tone and content Please don t Share Slack live stream or poster session links with othersBroadcast the conference to unregistered participantsCapture transmit or redistribute data presented at the meeting unless presenter gives explicit consentUse offensive language in your postsEngage in rudeness or personal attacks Additional information can be found in our Code of Conduct Health and well being It is important to stay healthy and move around especially when you are attending an event virtually We have put together a few coffee break stretches and yoga videos in the events Slack workspace for you to enjoy during the event How to ask questions Questions during and after the talks can be asked in live streaming platform The chair moderates the questions and shares them with the speaker If time runs out or you think of a question later you can use Slack to ask your questions in the dedicated session channels or via direct message Time zone The programme is planned based on Central European Summer Time CEST unless otherwise stated As many virtual participants are attending from around the world we do our best to accomodate as many timezones as possible when creating the programme Please take your time zone into consideration when planning your attendance Virtual event platforms We are using a virtual event platform for this conference More information about the platform will be shared ahead of the conference Sponsors Gold sponsor Silver sponsors Media Partnership Molecular Systems Biology an EMBO Press journal Molecular Oncology a FEBSPRESS journal International Union of Biochemistry and Molecular Biology Open Biology a Royal Society journal Sponsorship Opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a Sponsorship Brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsoring embl de Pre conference webinars Pre symposium webinars will take place on Monday 22 November 2021 Participation in this webinar is free of charge for registered conference attendees The number of available places is limited first come first served All registered conference attendees will receive an email with a registration link 12 00 12 50 Berlin Germany Bristol Myers Squibb Precision Medicine meets immuno oncology innovative biomarkers and beyond Speaker Dr Christoph Benedikt Westphalen Comprehensive Cancer Center M nchen Immunotherapeutic interventions have revolutionised the treatment landscape in various malignancies A more profound understanding of mechanisms underlying response and resistance to this class of agents will help to maximise patients benefit A range of potentially predictive biomarkers beyond PD L1 and dMMR MSI are under investigation to help identify patients qualifying for immune therapy Furthermore additional modalities such as digital pathology artificial intelligence and functional imaging are coming of age This seminar aims to give an overview on emerging biomarkers and technologies supporting personalised approached in immunotherapy Diagenode DNA methylation in biofluids from genome wide studies to targeted approaches Speaker Matteo Tosolini PhD Business Development Manager Epigenomic Services Profiling Diagenode a Hologic Company DNA methylation is an epigenetic mechanism characterized by the addition of a methyl group to the DNA mainly at cytosines It can occur at different genomic locations and it can modify gene expression and function The profile of DNA methylation is tissue type and cell type specific A hallmark of cancer is the presence of an aberrant DNA methylation profile and this modification appears to happen early during carcinogenesis For these reasons DNA methylation can be used as a cancer specific biomarker Circulating cell free DNA cfDNA is composed by fragmented DNA released by different mechanisms into the bloodstream mainly from apoptotic cells including healthy body cells as well as cancer cells Analysis of cfDNA is very promising and has a great potential in cancer diagnostics given its noninvasive approach requiring only a blood or plasma sample in a process known as liquid biopsy Interestingly cfDNA retains the genetic and epigenetic information of the tissue of origin Circulating tumour DNA ctDNA meaning DNA fragments that originate from cancer cells can thus be used as potential biomarker for early cancer detection and diagnosis The first proof of concept was published last year by the Circulating Cell free Genome Atlas consortium CCGA The analysis of methylated cfDNA by bisulfite sequencing does not come without challenges as those samples are in low quantity and poor quality because cfDNA is highly fragmented and the ctDNA is diluted by cfDNA from normal body cells In this webinar we will present how Diagenode can help by applying our workflow of DNA methylation biomarker discovery and validation in biofluids We will start with Whole Genome Bisulfite Sequencing WGBS on cfDNA to determine the CpGs and the pattern of DNA methylation by using standard statistics as well as data mining approaches and to discriminate between different groups We will proceed with the most adapted and fully customized Targeted Bisulfite Sequencing approach on cfDNA to validate the previously identified CpG methylation signature as biomarker and screen a higher number of patients 13 00 13 50 Berlin Germany Arima Genomics 3D Genome Analysis Identifies Therapeutic Targets in Pediatric Brain Cancer Speaker Anthony Schmitt PhD SVP of Science Arima Genomics Ependymoma is a tumor of the brain or spinal cord The two most common and aggressive molecular groups of ependymoma occur mainly in young children and frequently recur after treatment Although molecular mechanisms underlying these diseases have recently been uncovered they remain difficult to target Innovative therapeutic approaches are urgently needed Join this webinar to learn how we Uncovered chromosomal rearrangements and regulatory mechanisms underlying aberrant expression of genes that are essential for ependymoma tumorigenesis Identified potential novel therapeutic vulnerabilities in ependymoma and validated newly identified therapeutic targets through genetic or pharmacologic inhibition experiments Revealed tumor dependency genes and pathways by oncogenic 3D genome conformations even in tumors that lack known genetic alterations Dovetail Genomics Structural and functional heterogeneity in the spatial organization of glioblastoma patient genomes Speaker Argyris Papantonis Dovetail Genomics Recent work has established that 3D genome organization is causally linked to gene expression control also in tumors and cancer In addition most cancer genomes are infested with structural variants SVs that contribute to oncogenesis and cancer progression via various mechanisms We performed Hi C experiments on glioblastoma stem cells GSCs from 26 patients to generate a resource of 13 billion contacts We used this Hi C data resource to detect and characterize patient specific SVs and then build individualized genome references We identified 1100 high confident SVs which were highly heterogeneously distributed across the 26 patient genomes Following integration with gene expression data and despite heterogeneity we found partially recurrent effects on gene expression misregulation that could be linked to the formation of many hundreds of neo TADs and neo loops in these GSC genomes Together this is the first such comprehensive approach in leveraging 3D genome heterogeneity to understand regulatory dependencies in glioblastoma...

Jan Korbel, Núria López-Bigas, Seishi Ogawa, Elli Papaemmanuil

EMBL Conference

Virtual

18 November 2021

Introduction to qualitative modelling with MaBoSS

Edit

November 18, 2021 15:002021WebinarVirtual

Description Boolean modelling uses a simple representation of biological entities as either active or inactive and describes their relations with logical formulas MaBoSS extends Boolean modelling by adding a notion of continuous time with the introduction of rates of in activation This enable the representation of physical time and of processes with different time scales MaBoSS simulate multiple stochastic trajectories and produces trajectories of the probabilities of the system state This webinar will introduce the concepts of boolean modelling and MaBoSS continuous time boolean modelling and will then demonstrate the use of WebMaBoSS a web interface designed for easily simulating MaBoSS models About the speaker Dr Vincent No l M is a postdoctoral student at the Computational Systems Biology of Cancer team of the U900 in Institut Curie His research interests concern modelling of biological systems where he has experience in both construction and analysis of these models He did his PhD in applied mathematics studying simplifications of ODE models and then did his first postdoc within a molecular biology unit building a model of Ras Mapk signaling in Y1 tumor cells He also developed tools to simplify the construction and analysis of models and the reproducibility of this work He has a good experience in the optimisation of numerical simulation workflows and has been working on MaBoSS for more than three years...

Vincent Noël

Virtual

17 November - 20 November 2021

Metabolism meets epigenetics

Edit

Open access: publications and preprints

Edit

October 27, 2021 15:302021WebinarVirtual

Description Continuing our series on open access in this webinar we will discuss the role of EMBL in making science open We will introduce Europe PMC an open free database of life science publications and preprints and explain how Europe PMC supports open access policies of many organisations including EMBL We will highlight how open access underpins innovation and the importance of licensing for reuse Then we will illustrate how open access to publications supports scientific reproducibility and the role that proper data citation plays in this process Finally we will look at preprints as a tool for researchers to rapidly and openly share their work decoupled from the formal peer review process...

Mariia Levchenko

Virtual

25 October - 3 November 2021

Solution scattering from biological macromolecules

Edit

October 25, 2021 00:002021CourseVirtual

...

M. Gräwert, A. Kikhney, D. Svergun

EMBO Practical Course

Virtual

21 October 2021

Analysis of huge metabolic models with COBREXA.jl

Edit

October 21, 2021 15:002021WebinarVirtual

Description COBREXA jl is a new software package to enable the analysis and simulation of large metabolic models by taking advantages of modern HPC infrastructure Mainly it advanced the scalability of constraint based method using the Julia programing language and its mathematic ecosystem as a base building block We will talk about the problems that motivated the development of COBREXA jl and show several of its main applications We will show the COBREXA jl interface that allows biologists and bioinformaticians to easily specify large amounts of analyses and execute it on supercomputers Later we will use COBREXA for creating a model of a small microorganism community and demonstrate how the software helps to answer questions about the viability and chemical activity of microbe ecosystems About the speakerMiroslav Kratochv l has recently finished his PhD in computer science at Charles University in Prague currently he is a researcher focusing on bioinformatics oriented topics at Luxembourg Centre for Systems Biomedicine His research concerns mainly the high performance algorithms for processing large datasets from life sciences...

Miroslav Kratochvil

Virtual

20 October 2021

Open access: Finding and accessing open data

Edit

October 20, 2021 15:302021WebinarVirtual

Description Our open access webinar series continues with an introduction to finding and accessing open data The webinar will begin with an overview of the kind of open access data available from EMBL EBI and a demonstration of finding data on the EMBL EBI website using EBI Search The concept of programmatic access will also be introduced with information about how and why APIs can be used to access open data and guidance on where to find more detail about access to different EMBL EBI resources The webinar will then focus on BioStudies a database that holds descriptions of biological studies and links to data both in EMBL EBI resources and beyond This section will provide an introduction to BioStudies examples of how it can be used in your research and a demonstration of the resource itself...

Ugis Sarkans, Anna Swan

Virtual

20 October - 21 October 2021

Introduction to the EMBL-EBI bioinformatics tools framework

Edit

October 20, 2021 00:002021CourseVirtual

Description The EMBL EBI provides free access to a wide range of core bioinformatics sequence analysis applications via the web and via programmatic access This course is split into two main sessions running over two days The first session focuses on learning about the bioinformatics applications provided and how to use them in conjunction with a range of biological databases There will be a focus on sequence alignment e g Clustal Omega and MAFFT and sequence similarity search NCBI BLAST and FASTA tools The second session focuses on alternative approaches to accessing the tools beyond the website We will explore the Tools APIs and various examples of how the tools can be accessed on the command line and integrated into workflows...

Ajay Mishra

Virtual

20 October - 22 October 2021

Bringing molecular structure to life: 50 years of the PDB

Edit

October 20, 2021 00:002021ConferenceVirtual

Description OverviewSpeakersProgrammePractical InformationSponsors Overview EMBL is committed to sharing research advances and sustaining scientific interaction throughout the coronavirus pandemic We are delighted to announce that this conference is going virtual and invite you to join us online Join this conference and celebrate the 50th anniversary of The Protein Data Bank PDB with us With over 1 million unique users worldwide and more than 400 biomedical data resources the PDB represents the achievements and milestones of the structural biology community The PDB is one of the oldest surviving archives in any biomedical field The structural biology community established the single worldwide archive for macromolecular structure data in 1971 The PDB has embraced a culture of open access leading to its widespread use by the research community with nowadays more than 1 million unique users worldwide and by more than 400 biomedical data resources Structural biology and structural bioinformatics have had an enormous impact on our understanding of the mechanism and function of biological macromolecules The PDB acts as a custodian for all these data representing the achievements and milestones of the structural biology community The archive is managed by the Worldwide Protein Data Bank consortium wwPDB which includes partner sites in Asia Europe and America making this a truly global effort The 50th anniversary is an opportunity to celebrate the advances in structural biology and bioinformatics and peer into the future prospects for these fields Session topics Structural biology and applications in health and the environmentRNA DNA molecular machinesThe next 50 years Genomics meets structural biologyLatest advancesThe next 50 years Future perspectives part 1 The next 50 years Future perspectives part 2 Call for artwork by 8 September 2021 An artwork exhibition will be part of the conference bringing awareness to the 50th anniversary of the PDB The conference participants can submit an artwork representing scientific and or societal concepts relating to a structure in the Protein Data Bank The artwork can be created using any technique or media however we will require a high resolution image of the artwork for display in the virtual exhibition More information about submitting an artwork or abstract can be found under the tab Practical Information Speakers Bissan Al Lazikani The Institute of Cancer Research UK Cheryl H Arrowsmith University Health Network Canada M Madan Babu St Jude Children s Research Hospital USA David Baker University of Washington USA Drew Berry Walter and Eliza Hall Institute of Medical Research Australia Wah Chiu Stanford University USA Patrick Cramer Max Planck Institute for Biophysical Chemistry Germany Petra Fromme Arizona State University USA Donald Hilvert ETH Zurich Switzerland Martin Jinek University of Zurich Switzerland John Jumper DeepMind UK Julia Mahamid EMBL Heidelberg Germany Christine Orengo University College London UK Lori A Passmore MRC Laboratory of Molecular Biology UK Jane Shelby Richardson Duke University School of Medicine USA David Stuart University of Oxford UK Nicolas Thom Friedrich Miescher Institute for Biomedical Research Switzerland Janet Thornton EMBL EBI Hinxton UK Sameer Velankar EMBL EBI Hinxton UK Panel Chair Peter Rosenthal The Francis Crick Institute UK Scientific Organisers Stephen Cusack EMBL Grenoble France Gerard Kleywegt EMBL EBI Hinxton UK Christoph M ller EMBL Heidelberg Germany Christine Orengo University College London UK Janet Thornton EMBL EBI Hinxton UK Sameer Velankar EMBL EBI Hinxton UK Matthias Wilmanns EMBL Hamburg Germany Conference Organiser Lea Hohmann EMBL Heidelberg Germany Aline Schnieder EMBL Heidelberg Germany Programme Got something to say Tweet it EMBLPDB Day 1 Wednesday 20 October 2021 Time CEST Speaker 11 00 11 15 Opening remarks by Scientific OrganisersIntroductory Session Session Chair Gerard Kleywegt11 15 11 45Historical perspective of the PDB the archive that led the way to open scienceJane Richardson Duke University School of Medicine USAJanet Thornton EMBL EBI Hinxton UKAVAILABLE ON DEMAND AFTER LIVE STREAM 11 45 12 15Advances in Structural VirologyDave Stuart University of Oxford UKAVAILABLE ON DEMAND AFTER LIVE STREAM12 15 12 45How Representative is the Protein Databank of All the Protein Structures in Nature Christine Orengo University College London UKAVAILABLE ON DEMAND AFTER LIVE STREAM12 45 13 15Meet the Speakers13 15 13 30Break13 30 14 30Poster session 1 Artwork exhibitionSession 1 Structural biology applications in health and theenvironment Session Chair Matthias Wilmanns14 30 15 00Haven t got a glue reprogramming ubiquitin ligases with molecular glue degradersNicolas Thom Friedrich Miescher Institute for BiomedicalResearch Switzerland15 00 15 15Structure of Escherichia coli respiratory complex I reconstituted into lipid nanodiscs reveals an uncoupled conformationPiotr Kolata Center for Structural Biology Vlaams Instituut voor Biotechnologie BelgiumAVAILABLE ON DEMAND AFTER LIVE STREAM15 15 15 45Exploiting structures and Big Data for drug discoveryBissan Al Lazikani The Institute of Cancer Research UKAVAILABLE ON DEMAND AFTER LIVE STREAM 15 45 16 00Break16 00 16 15The structure of the native CNGA1 CNGB1 CNG channel from retinal rodsJacopo Marino Paul Scherrer Institut Switzerland16 15 16 45The Structural Genomics Consortium SGC structural biology to illuminate the dark proteome and catalyze drug discoveryCheryl Arrowsmith University Health Network CanadaAVAILABLE ON DEMAND AFTER LIVE STREAM16 45 17 15Meet the Speakers17 15 18 00Optional networking programme Quiz timeThe Great PDB50 Quiz Anybody can win It s that hard 17 45 18 15Meet the Editor Session in break out rooms Trends in Biochemical Sciences Sannie Culbertson Nature Communications Karin Kuehnel Nature Methods Allison Doerr Nature Structural Molecular Biology Carolina Perdigoto Day 2 Thursday 21 October 2021 Time CEST Speaker Session 2 RNA DNA molecular machines Session Chair Stephen Cusack11 00 11 30Structural studies of gene transcription and viral replicationPatrick Cramer Max Planck Institute for Biophysical Chemistry GermanyAVAILABLE ON DEMAND AFTER LIVE STREAM11 30 11 45Complex nucleoprotein assemblies promote antibiotic resistance spreadingGeorgy Smyshlyaev EMBL Heidelberg GermanyAVAILABLE ON DEMAND AFTER LIVE STREAM11 45 12 15Macromolecular machines involved in mRNA 3 end processingLori Passmore MRC Laboratory of Molecular Biology UKAVAILABLE ON DEMAND AFTER LIVE STREAM12 15 12 30Break12 30 12 45Bridging of DNA breaks activates PARP2 HPF1 to modify chromatinSilvija Bilokapic St Jude Children s Research Hospital USAAVAILABLE ON DEMAND AFTER LIVE STREAM12 45 13 15Molecular mechanisms of CRISPR associated genome editor nucleases and transposonsMartin Jinek University of Zurich SwitzerlandAVAILABLE ON DEMAND AFTER LIVE STREAM13 15 13 45Meet the SpeakersSession 3 The next 50 years Genomics meets structural biology Session Chair Christine Orengo13 45 14 45Poster Session 2 Artwork exhibition14 45 15 15Enzyme engineeringDon Hilvert ETH Z rich SwitzerlandAVAILABLE ON DEMAND AFTER LIVE STREAM15 15 15 30PDB wide identification of physiological hetero oligomeric assemblies based on conserved quaternary structure geometrySucharita Dey Indian Institute of Technology Jodhpur IndiaAVAILABLE ON DEMAND AFTER LIVE STREAM15 30 16 00Structural and systems biology understanding variationMadan Babu St Jude Children s Research Hospital UKAVAILABLE ON DEMAND AFTER LIVE STREAM16 00 16 15Break16 15 16 45AlphaFold and the role of deep learning in structural biologyJohn Jumper DeepMind UKAVAILABLE ON DEMAND AFTER LIVE STREAM16 45 17 15The coming of age of de novo protein designDavid Baker University of Washington USAAVAILABLE ON DEMAND AFTER LIVE STREAM17 15 17 45Meet the Speakers17 45 18 15Optional networking programme Speed networking Day 3 Friday 22 October 2021 Time CEST Speaker Session 4 Latest advances Session Chair Christoph M ller11 00 12 00Respiration The dynamic multi enzyme pathway from Glucose to ATPDrew Berry Walter and Eliza Hall Institute of Medical Research AustraliaAVAILABLE ON DEMAND AFTER LIVE STREAM12 00 12 20The structural changes of phytochrome photoactivation revealed by femto and picosecond serial femtosecond X ray crystallographyMadan Kumar Shankar Gothenburg University SwedenAVAILABLE ON DEMAND AFTER LIVE STREAM12 20 12 40Quantifying radiation damage to protein crystal structures inthe PDBKathryn Shelley University of Bristol UKAVAILABLE ON DEMAND AFTER LIVE STREAM12 40 13 00Refactoring the B factor intuitively extracting structural dynamics from macromolecular disorderNicholas Pearce Vrije Universiteit Amsterdam NetherlandsAVAILABLE ON DEMAND AFTER LIVE STREAM13 00 13 30Meet the Speakers13 30 13 45BreakSession 5 The next 50 years future perspectives part 1 Session Chair Janet Thornton13 45 14 15Enabling discovery by in cell structural biologyJulia Mahamid EMBL Heidelberg GermanyAVAILABLE ON DEMAND AFTER LIVE STREAM14 15 14 45Femtosecond Crystallography with XFELs From static pictures to dynamics of biomolecules in actionPetra Fromme Arizona State University USAAVAILABLE ON DEMAND AFTER LIVE STREAM14 45 15 00BreakSession 6 The next 50 years future perspectives part 2 Session Chair Janet Thornton15 00 15 30Cryo EM of RNA at Near Atomic ResolutionsWah Chiu Stanford University USAAVAILABLE ON DEMAND AFTER LIVE STREAM15 30 16 00Making structural data accessibleSameer Velankar EMBL EBI Hinxton UKAVAILABLE ON DEMAND AFTER LIVE STREAM16 00 17 00Panel Discussion on the future of structural biology and thePDBChaired by Peter RosenthalPanelists Wah Chiu Petra Fromme Don Hilvert John Jumper Jan Kosinski Julia MahamidAVAILABLE ON DEMAND AFTER LIVE STREAM17 00 17 15Closing remarks by the Scientific Organisers17 15 17 45Meet the Speakers Practical Information Registration Fees and Abstract Artwork Submission Registration Fees include access to all of the talks digital poster sessions and online group discussions and help us cover our costs to run the event For further information please refer to the FAQ page Academia PI Faculty75 EuroAcademia Post doc50 EuroPhD Student Emeritus Retired15 EuroIndustry200 EuroEMBL StaffIntranet access Accredited journalists may be eligible to register for a complimentary registration Registrants may be required to provide accreditation or equivalent proof of press membership after registration Please contact Aline Schnieder for more information Confirmation and Payment Registration will be on a first come first served basis Your place can only be confirmed after payment of the registration fee Types of payments accepted are international bank transfers and credit card payments Artwork submission Artwork submission deadline 8 September 2021 23 59 Europe Berlin Only registered participants are eligible to submit an artwork We only accept online artwork submissions The artwork should be an original piece of art representing scientific and or societal concepts relating to a structure in the Protein Data Bank The artwork can be created using any technique or media however we will require a high resolution image of the artwork for display in the virtual exhibition After you have logged in and successfully registered you will receive an email asking you to submit your artwork Click on the link provided and enter your artwork Alternatively you can submit your artwork by clicking on the link on the confirmation page directly after registering A selection process will take place with the results announced 2 3 weeks after the artwork submission deadline Abstract submission Abstract submission deadline 15 September 2021 23 59 Europe Berlin Late abstracts for poster presentations are accepted until 27 September 23 59 Europe Berlin Only registered participants are eligible to submit an abstract We only accept online abstract submissions After you have logged in and successfully registered you will receive an email asking you to submit your abstract Click on the link provided and enter your abstract in the text box provided Alternatively you can submit your abstract by clicking on the link on the confirmation page directly after registering When submitting your abstract you can also apply for an oral or poster presentation A selection process will take place with the results announced 2 3 weeks after the abstract submission deadline Financial Assistance Financial Assistance Financial Fee Waivers All academic and student registrants are invited to apply for a registration fee waiver provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO The registration fee waiver covers the registration sum that you have paid to attend the meeting Conference participants are not required to pre pay the registration fee to be selected for a fee waiver for a virtual meeting If you have already paid the registration fee and are awarded a fee waiver it will be reimbursed after the meeting Childcare Grants For participants and speakers with childcare responsibilities there is the possibility to apply for a grant provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO to offset childcare costs incurred when participating at a virtual event Eligible costs include fees for a babysitter or childcare facility or travel costs for a care giver Please note that priority will be given to early stage researchers Costs will be reimbursed after the meeting only once a reimbursement form and original receipts have been received Attendance at the event is required in order to be eligible to receive the reimbursement In order to apply for this grant you must be registered by the abstract submission deadline Application Applications for financial assistance can be submitted via the submission portal for the submission of abstracts for conferences by completing the Financial Assistance Application Section underneath the section for entering abstract motivation letter information The link to the portal can be found in the registration confirmation email that you will receive after registering for the conference For conferences if you are not submitting an abstract you can still apply for financial assistance in the submission portal Take a look at the instructions for applying for financial assistance Note that priority will be given to those submitting an abstract to present at the conference In your application you will be asked to answer questions regarding your motivation for applying and for registration fee waivers the reasons why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Selection The scientific organisers will select the recipients of registration fee waivers during the abstract selection process for conferences and the participant selection process for courses Results will be announced approximately 3 4 weeks before the event start date Selection results do not impact your admission to the meeting Registration fee waiver selection is based on your current work or study location your motivation for applying the reasons for needing financial support and the impact this event will have on your career Childcare grants are allocated based on career stage with priority given to early stage researchers Further details Check our list of external funding opportunities and read our information on attending a conference as an event reporter For further information about financial assistance please refer to the FAQ page Virtual Participation Guidelines Guidelines Please do Use the event specific hashtag as communicated during the event for any related tweetsTweet unless the speaker specifically says otherwiseBe mindful of unpublished dataBe respectful in tone and content Please don t Share Slack live stream or poster session links with othersBroadcast the conference to unregistered participantsCapture transmit or redistribute data presented at the meeting unless presenter gives explicit consentUse offensive language in your postsEngage in rudeness or personal attacks Additional information can be found in our Code of Conduct Health and well being It is important to stay healthy and move around especially when you are attending an event virtually We have put together a few coffee break stretches and yoga videos in the events Slack workspace for you to enjoy during the event How to ask questions Questions during and after the talks can be asked in live streaming platform The chair moderates the questions and shares them with the speaker If time runs out or you think of a question later you can use Slack to ask your questions in the dedicated session channels or via direct message Time zone The programme is planned based on Central European Summer Time CEST unless otherwise stated As many virtual participants are attending from around the world we do our best to accomodate as many timezones as possible when creating the programme Please take your time zone into consideration when planning your attendance Virtual event platforms We are using a virtual event platform for this conference More information about the platform will be shared ahead of the conference Sponsors Media Partners EMBO Journal an EMBO Press journal International Union of Biochemistry and Molecular Biology Open Biology a Royal Society journal Sponsorship Opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a Sponsorship brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsoring embl de...

Stephen Cusack, Gerard Kleywegt, Christoph Mueller, Christine Orengo, Janet Thornton, Sameer Valenkar, Matthias Wilmanns

EMBL Conference

Virtual

18 October 2021

Using the Ensembl genome browser to interrogate disease-associated variants

Edit

October 18, 2021 00:002021CourseVirtual

Description A hands on workshop introducing the principles of interrogating genetic variants using the Ensembl genome browser and using the Ensembl Variant Effect Predictor to map variants onto Ensembl GENCODE transcripts and other genomic features to determine their likely functional effects...

Michal Szpak

Virtual

14 October 2021

Sight, vision and UniProt proteins

Edit

October 14, 2021 15:002021WebinarVirtual

Description Join us on World Sight Day to find out about our ongoing curation project at UniProt to annotate proteins involved in eye development and disease Globally around 2 2 billion people have a near or distance vision impairment of whom at least 1 billion have a condition that could have been prevented or is yet to be treated WHO World report on vision 2019 One of the many curation efforts at UniProt aims to support biomedical research into eye health and treatment by focusing on curating proteins in human and model organisms that have an involvement in eye formation maintenance and or health This webinar will demonstrate how we selected these proteins then collected interpreted and integrated information from a range of sources to provide comprehensive and high quality overview of their sequence and functional information It will also discuss how we also annotate photoreceptor cell and eye proteins in non human organisms to help scientists understand common components and regulatory mechanisms that underly the formation and maintenance of visual systems This webinar is part of a series covering various aspects of UniProt view other upcoming webinars here...

Kate Warner, Emily Bowler-Barnett

Virtual

13 October 2021

Open access: Why build open source software and how to do it successfully

Edit

October 13, 2021 15:302021WebinarVirtual

Description Continuing our series of webinars on the topic of open access during this webinar we will define what open software is discuss motivations and challenges of producing open code and software as well as basic concepts that help to do so We will explain the many forms and dimensions of open software and its development highlighting the importance of documentation testing packaging communication and community in order to create successful and sustainable software Speakers Renato Alves Bio IT EMBL Following a PhD in human bacterial metagenomics and metatranscriptomics I took the role of Bio IT project coordinator at EMBL Heidelberg providing computational support to the research community at EMBL For over 15 years I have contributed to several open and closed source software projects using a multitude of programming languages and technologies from web to big data and cloud Brice Letcher EMBL EBI I am a 4th year PhD student at the Iqbal lab working in computational microbial genomics In my PhD I develop an open source tool to build and genotype graphs of genomes I am passionate about good software engineering and a keen contributor to the bioinformatics community notably through building a formatting tool for snakemake workflow manager files...

Renato Alves, Brice Letcher

Virtual

13 October - 15 October 2021

The non-coding genome

Edit

October 13, 2021 00:002021ConferenceVirtual

Description OverviewSpeakersProgrammePractical InformationSponsorsAbout Overview EMBO and EMBL are committed to sharing research advances and sustaining scientific interaction throughout the coronavirus pandemic We are delighted to announce that this conference is going virtual and invite you to join us online Symposium Overview This symposium will explore the diverse dynamic and multifaceted roles of RNA across a spectrum of cellular processes It will provide an interdisciplinary discussion of the roles of non coding RNAs in both prokaryotes and eukaryotes with the aim of enhancing our understanding of gene regulation and function In the 50 years since RNA was identified as a central component in the flow of genetic information it has become increasingly clear that RNA performs many additional diverse and interesting functions Regulatory RNAs are known to play central roles across numerous biological processes required for cell viability and function Moreover prokaryotic and eukaryotic genomes are pervasively transcribed to generate many additional RNAs with unknown functions raising the question What else does RNA do Session Topics Functions and mechanisms of small RNAsRNA granules and localisationLong non coding RNAs and circular RNAsOther types of small RNAsRNA modificationViral RNAs and immunity and RNA therapeutics What past participants say The symposium was INCREDIBLY good It was almost perfect well organised and with excellent chosen speakers It provided lot of opportunities to learn discuss share and network among young and expert scientists I would be happy to join again any time possible Monah Abou Alezz Institute of Molecular Genetics L L Cavalli Sforza National Research Council Pavia Italy Speakers Keynote Speakers Asifa Akhtar Max Planck Institute of Immunobiology and Epigenetics Germany Joshua Mendell UT Southwestern Medical Center USA Speakers Marie Laure Baudet University of Trento Italy Howard Y Chang Stanford University USA Caroline Dean John Innes Centre UK Sven Diederichs University Hospital Freiburg Germany Amanda E Hargrove Duke University USA Lin He University of California Berkeley USA Samie R Jaffrey Cornell University USA Gunter Meister University of Regensburg Germany Kai Papenfort Friedrich Schiller University of Jena Germany Ramesh Pillai University of Geneva Switzerland Kathrin Plath UCLA School of Medicine USA Oded Rechavi Tel Aviv University Israel Noam Stern Ginossar Weizmann Institute of Science Israel t p nka Va ov Masaryk University Czech Republic Sandra L Wolin National Institutes of Health USA Scientific Organisers Irene Bozzoni Sapienza University of Rome Italy V Narry Kim Seoul National University and Institute for Basic Science South Korea Gisela Storz National Institutes of Health USA Igor Ulitsky Weizmann Institute of Science Israel Conference Organiser Maryann Heck EMBL Heidelberg Germany Chris Stocks EMBL Heidelberg Germany Programme All talks will be live streamed with Q A sessions after each talk Information on the live stream and access to the discussion platform and digital posters will be provided shortly before the start of the event Access to the recorded talks will be available for 2 weeks after the start of the event All times in the programme below are shown as the time in Europe Berlin To find out the equivalent time zone in your location enter Berlin the programme time and date along with your city into the Time Zone Converter Got something to say Tweet it EESNoncoding Day 1 Wednesday 13 October 2021 Time Europe Berlin Speaker14 00 14 10 Opening remarks by V Narry KimAVAILABLE ON DEMAND AFTER LIVE STREAM14 10 16 40Session 1 Functions and mechanisms of small RNAsSession chairs Narry Kim and Marie Laure Baudet14 10 14 35ncRNAs a non canonical mode of intracellular transport through organelle hitchhikingMarie Laure Baudet University of Trento Italy14 35 15 00C elegans Parental Experiences Regulate a Critical Decision Made by the ProgenyOded Rechavi Tel Aviv University IsraelAVAILABLE ON DEMAND AFTER LIVE STREAM15 00 15 15The SHAPE of human primary microRNAsSeungchan Baek Seoul National University South KoreaAVAILABLE ON DEMAND AFTER LIVE STREAM15 15 15 30Break15 30 15 45A SUMO dependent regulatory switch connects the piRNA pathway to the heterochromatin machinery in DrosophilaChangwei Yu Institute of Molecular Biotechnology IMBA Vienna AVAILABLE ON DEMAND AFTER LIVE STREAM15 45 16 00Cellular abundance shapes function in piRNA guided genome defenseAstrid Haase National Institute of Diabetes and Digestive and Kidney Diseases National Institutes of Health USA AVAILABLE ON DEMAND AFTER LIVE STREAM16 00 16 25From Strings of Nucleotides to Collective Behaviors Lessons from BacteriaKai Papenfort Friedrich Schiller University of Jena GermanyAVAILABLE ON DEMAND AFTER LIVE STREAM16 25 16 50Genome regulation by long noncoding rnasHoward Y Chang Stanford University USAAVAILABLE ON DEMAND AFTER LIVE STREAM16 50 17 20Meet the speakers from Session 1 in Zoom rooms with Marie Laure Baudet Oded Rechavi Seungchan Baek Changwei Yu Astrid Haase Kai Papenfort and Howard Y Chang17 20 18 20Poster session 1 live chats and video calls with poster presenters with last names A F 18 20 19 15Session 2 RNA granules and localizationSession chairs Marie Laure Baudet and Gisela Storz18 20 19 00Keynote Lecture Regulation and function of noncoding RNAs the NORAD Pumilio pathway as exemplarJoshua Mendell UT Southwestern Medical Center USAAVAILABLE ON DEMAND AFTER LIVE STREAM19 00 19 25Protein gradients and X inactivation by the lncRNA XistKathrin Plath UCLA School of Medicine USA19 25 19 40In situ 3 UTR cleavage of transcripts localized in sympathetic neuron axonsCatia Andreassi University College London UKAVAILABLE ON DEMAND AFTER LIVE STREAM19 40 19 55Unraveling the interplay between Nuclear Exosome targeting and Functional 3D chromatin loopingOlivier Cuvier CNRS France19 55 20 25Meet the speakers from Session 2 in Zoom rooms with Joshua Mendell Kathrin Plath Catia Andreassi and Olivier Cuvier20 25 21 10Social programme speed networking Day 2 Thursday 14 October 2021 Time Europe Berlin Speaker14 00 16 50 Session 3 Long non coding RNAs and circular RNAsSession chairs Igor Ulitsky and Gunter Meister14 00 14 40Keynote Lecture Dosage compensation of the X chromosome An epigenetic phenomenon involving chromatin regulators and long non coding RNAsAsifa Akhtar Max Planck Institute of Immunobiology and Epigenetics GermanyAVAILABLE ON DEMAND AFTER LIVE STREAM14 40 15 05The complexity of COOLAIRCaroline Dean John Innes Centre UKAVAILABLE ON DEMAND AFTER LIVE STREAM15 05 15 20MIR NATs aid proteostasis in neurodegenerationRoberto Simone University College London UK15 20 15 35Break15 35 15 50Distinct structural domains of MUNC lncRNA regulate gene expression during myogenesisRoza Przanowska University of Virginia USAAVAILABLE ON DEMAND AFTER LIVE STREAM15 50 16 15Transposons Friends or foes in preimplantation embryos Lin He University of California Berkeley USAAVAILABLE ON DEMAND AFTER LIVE STREAM16 15 16 40Non coding RNA RNA dependent Proteins in CancerSven Diederichs University Hospital Freiburg GermanyAVAILABLE ON DEMAND AFTER LIVE STREAM16 40 17 10Meet the speakers Session 3 in Zoom rooms with Asifa Akhtar Caroline Dean Roberto Simone Roza Przanowska Lin He and Sven Diederichs17 10 18 10Poster session 2 live chats and video calls with poster presenters with last names G O 18 10 19 30Session 4 Other types of small RNAsSession chairs Kathrin Plath and Irene Bozzoni18 10 18 35Damaged tRNAs as signaling moleculesSandra L Wolin National Institutes of Health USAAVAILABLE ON DEMAND AFTER LIVE STREAM 18 35 19 00A tRNA sensor for balancing mitochondrial translationGunter Meister University of Regensburg GermanyAVAILABLE ON DEMAND AFTER LIVE STREAM19 00 19 15New group of bacterial Argonaute proteins with RNA target specificityDaria Esyunina Institute of Molecular Genetics National Research Centre Kurchatov Institute RussiaAVAILABLE ON DEMAND AFTER LIVE STREAM19 15 19 30Oxygen induced small RNA FoxI provides the noncoding arm of the Sigma E response of the cancer associated Fusobacterium nucleatumFalk Ponath Helmholtz Institute for RNA based Infection Research HIRI Germany19 30 20 00Meet the speakers from Session 4 in Zoom rooms with Sandra L Wolin Gunter Meister Daria Esyunina and Falk Ponath20 00 20 15Social programme bar mixer Day 3 Friday 15 October 2021 Time Europe Berlin Speaker13 00 14 00 Poster session 3 live chats and video calls with poster presenters with last names P Z 14 00 16 35Session 5 RNA modificationSession chairs Irene Bozzoni and Sandra L Wolin14 00 14 25The secret life of 5 mRNA fragments t p nka Va ov Masaryk University Czech Republic14 25 14 40Interaction of lincrna LENOX with the gtpase RAP2C promotes oxidative phosphorylation melanoma cell survival and resistance to BRAF inhibitionGiovanni Gambi Institute of Genetics and Molecular and Cellular Biology France14 40 14 55Intergenerational hormesis is regulated by heritable 18S rRNA methylationEric Greer Harvard Medical School Boston Children s Hospital USAAVAILABLE ON DEMAND AFTER LIVE STREAM14 55 15 10Break15 10 15 25A single m6A site is an antimorph switch for a cancer associated lncRNAAaron Johnson University of Colorado School of Medicine United States of AmericaAVAILABLE ON DEMAND AFTER LIVE STREAM15 25 15 50Gene regulation by RNA modificationsRamesh Pillai University of Geneva Switzerland15 50 16 15Regulation of RNA biology and cap methylations by juxtacap sequencesSamie Jaffrey Cornell University USA16 15 16 45Meet the speakers Session 5 in Zoom rooms with t p nka Va ov Giovanni Gambi Eric Greer Aaron Johnson Ramesh Pillai and Samie Jaffrey16 45 18 35Session 6 Viral RNAs and immunity and RNA therapeuticsSession chairs t p nka Va ov and Gisela Storz16 45 17 10Translational Remodeling by SARS CoV 2 InfectionNoam Stern Ginossar Weizmann Institute of Science IsraelAVAILABLE ON DEMAND AFTER LIVE STREAM17 10 17 35Fundamental approaches to targeting noncoding RNAs with small moleculesAmanda Hargrove Duke University USAAVAILABLE ON DEMAND AFTER LIVE STREAM17 35 17 50Artificial circular RNA sponges as a novel RNA therapeutic for molecular biology and medicineOliver Rossbach University of Giessen GermanyAVAILABLE ON DEMAND AFTER LIVE STREAM17 50 18 05Prediction and pan cancer analysis of mammalian transcripts involved in target directed miRNA degradationFrancesco Nicassio Italian Institute of Technology ItalyAVAILABLE ON DEMAND AFTER LIVE STREAM18 05 18 15Closing remarks by Gisela StorzAVAILABLE ON DEMAND AFTER LIVE STREAM18 15 18 45Meet the speakers from Session 6 in Zoom rooms with Noam Stern Ginossar Amanda Hargrove Oliver Rossbach and Francesco Nicassio Practical Information Registration Fees and Abstract Submission Registration Fees include access to all of the talks digital poster sessions and online group discussions and help us cover our costs to run the event For further information please refer to the FAQ page Academia190 EuroPhD Student140 EuroIndustry240 EuroEMBL StaffIntranet access Accredited journalists may be eligible to register for a complimentary registration Registrants may be required to provide accreditation or equivalent proof of press membership after registration Please contact Maryann Heck for more information Confirmation and Payment Registration will be on a first come first served basis Your place can only be confirmed after payment of the registration fee Types of payments accepted are international bank transfers and credit card payments Abstract submission Only registered participants are eligible to submit an abstract We only accept online abstract submissions After you have logged in and successfully registered you will receive an email asking you to submit your abstract Click on the link provided and enter your abstract in the text box provided Alternatively you can submit your abstract by clicking on the link on the confirmation page directly after registering When submitting your abstract you can also apply for an oral or poster presentation A selection process will take place with the results announced 2 3 weeks after the abstract submission deadline Financial Assistance Registration Fee Waivers All academic and student registrants are invited to apply for a registration fee waiver provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO The registration fee waiver covers the registration sum that you have paid to attend the meeting Conference participants are not required to pre pay the registration fee to be selected for a fee waiver for a virtual meeting If you have already paid the registration fee and are awarded a fee waiver it will be reimbursed after the meeting Course participants are required to pay the course fee in advance which will then be reimbursed after the recipient has attended the course Childcare Grants For participants and speakers with childcare responsibilities there is the possibility to apply for a grant provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO to offset childcare costs incurred when participating at a virtual event Eligible costs include fees for a babysitter or childcare facility or travel costs for a care giver Please note that priority will be given to early stage researchers Costs will be reimbursed after the meeting only once a reimbursement form and original receipts have been received In order to apply for this grant you must be registered by the abstract submission deadline Boehringer Ingelheim Fonds Travel Grant Applies to selected courses only Availability will be indicated during the abstract or motivation letter submission process This grant covers costs related to your attendance to the course registration travel and accommodation costs The grant is restricted to PhD students and postdocs who conduct basic biomedical research Whether you are eligible to apply for a travel grant depends on when you received your university entrance qualification e g Abitur A Levels High School Diploma Final State Examination for PhD and MD students as well as graduates the university entrance qualification must not have been obtained more than 11 years ago at the time of the envisaged course for postdocs the university entrance qualification must not have been obtained more than 13 years ago at the time of the envisaged course Application Applications for financial assistance can be submitted via the submission portal for the submission of abstracts for conferences or the submission of motivation letters for courses by completing the Financial Assistance Application Section underneath the section for entering abstract motivation letter information The link to the portal can be found in the registration confirmation email that you will receive after registering for the conference or course For conferences if you are not submitting an abstract you can still apply for financial assistance in the submission portal Read the instructions on how to apply for financial assistance Note that priority will be given to those submitting an abstract to present at the conference In your application you will be asked to answer questions regarding your motivation for applying and for registration fee waivers the reasons why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application For some events applications for Childcare Grants will still be done by email Information about the grant will be sent out shortly after the abstract motivation letter deadline Please contact the event Conference Officer if you have any questions Selection The scientific organisers will select the recipients of registration fee waivers during the abstract selection process for conferences and the participant selection process for courses Results will be announced approximately 3 4 weeks before the event start date Selection results do not impact your admission to the meeting Registration fee waiver selection is based on your current work or study location your motivation for applying the reasons for needing financial support and the impact this event will have on your career Childcare grants are allocated based on career stage with priority given to early stage researchers Further details Check out this list of external funding opportunities or get more information on attending the conference as an event reporter For further information about financial assistance please refer to the FAQ page Virtual Participation Guidelines Guidelines Please do Use the event specific hashtag as communicated during the event for any related tweetsTweet unless the speaker specifically says otherwiseBe mindful of unpublished dataBe respectful in tone and content Please don t Share Slack live stream or poster session links with othersBroadcast the conference to unregistered participantsCapture transmit or redistribute data presented at the meeting unless presenter gives explicit consentUse offensive language in your postsEngage in rudeness or personal attacks Additional information can be found in our Code of Conduct Health and well being It is important to stay healthy and move around especially when you are attending an event virtually We have put together a few coffee break stretches and yoga videos in the events Slack workspace for you to enjoy during the event How to ask questions Questions during and after the talks can be asked in live streaming platform The chair moderates the questions and shares them with the speaker If time runs out or you think of a question later you can use Slack to ask your questions in the dedicated session channels or via direct message Time zone The programme is planned based on Central European Summer Time CEST unless otherwise stated As many virtual participants are attending from around the world we do our best to accomodate as many timezones as possible when creating the programme Please take your time zone into consideration when planning your attendance Virtual event platforms We are using a virtual event platform for this conference More information about the platform will be shared ahead of the conference Sponsors Media Partners EMBO Journal an EMBO Press journal International Union of Biochemistry and Molecular Biology Open Biology a Royal Society journal Wiley Sponsorship Opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a Sponsorship Brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsoring embl de About EMBO EMBL Symposia promote scientific communication and collaboration in the European research area They provide scientists with a platform to discuss and exchange ideas on forward looking topics and new developments in the life sciences Topics emphasise upcoming developments and the interdisciplinary nature of related fields Jointly funded and organised by EMBO and EMBL and complementary to their respective courses workshops and conference programmes the symposia promote scientific communication and collaboration All symposia are held in the EMBL Advanced Training Centre ATC in Heidelberg Germany or virtually...

Irene Bozzoni, V. Narry Kim, Gisela Storz, Igor Ulitsky

EMBO | EMBL Symposium

Virtual

11 October - 15 October 2021

Structural bioinformatics

Edit

October 11, 2021 00:002021CourseVirtual

Description Structural biology determining the three dimensional shapes of biomacromolecules and their complexes can tell us a lot about how these molecules function and the roles they play within a cell Data derived from structure determination experiments enables life science researchers to address a wide variety of questions 2021 marks 50 years of the Protein Data Bank PDB the single worldwide archive of experimental biomacromolecular structures highlighting the depth of knowledge available for understanding molecular structure and function This course explores bioinformatics data resources and tools for the investigation analysis and interpretation of biomacromolecular structures It will focus on how best to analyse and interpret available structural data to gain useful information given specific research contexts The course content will also cover predicting protein structure and function and exploring interactions with other macromolecules as well as with low MW compounds There will also be a short session covering the new AI predicted protein structures database AlphaFold DB This course will be a virtual event delivered via a mixture of live streamed sessions pre recorded lectures and tutorials with live support We will be using Zoom to run the live stream sessions all fully password protected with automated English closed captioning and transcription with support and networking opportunities provided by Slack In order to make the most out of the course you should make sure to have a stable internet connection throughout the week There will also be networking and short social activities throughout the course and efforts will be made to make these accessible at different time zones across the week Selected participants will be sent materials prior to the course These might include pre recorded talks and required reading or online training that will be essential to fully understand the course...

Meredith Willmott

Virtual

11 October - 15 October 2021

From specimens to genomes

Edit

October 11, 2021 00:002021CourseVirtual

Description This course will cover the entire arc of a reference genome project from sample acquisition and shipping through nucleic acid extraction sequencing assembly curation and annotation in public databases It will promote the use and reuse of aquatic genomic data build a community of researchers able to exploit these new data types and introduce them to the theory and practice of reference quality genome sequencing and assembly The course content will connect participants to researchers at the forefront of the biodiversity genomics revolution and meet with others worldwide who also aim to apply these new approaches to their study systems Participants will develop bioinformatics skills to quality assess raw genomic sequence data identify co bionts assemble data into a genome build assess and then annotate the model with biological significance Symbiosis lies at the heart of the origins of the eukaryotic cell and new symbiosis events today shape much of the natural world playing key roles in ecosystem engineering and in colonisation of extreme habitats such as hydrothermal vents Biological understanding of symbiosis will be hugely enhanced through the deep analysis of the genomes of the interacting partners and the Aquatic Symbiosis Genomics project is working globally to generate reference genomes for many symbints from marine and freshwater habitats Virtual course Participants will learn via a mix of lectures technical presentations group work and discussion sessions Practical experience will be developed through group activities and trainer led computational exercises Live sessions will be delivered using Zoom with additional support and communication via Slack Computational practicals will run on EMBL EBI s virtual training infrastructure meaning participants will not require access to a powerful computer or install complex software on their own machines Participants will need to be available between the hours of 09 45 17 30 GMT each day of the course Trainers will be available to assist answer questions and further explain the analysis during these times...

Lucie Smith

Virtual

7 October - 14 October 2021

Liquid Biopsies

Edit

October 07, 2021 23:002021CourseVirtual

Description OverviewSpeakers and TrainersProgrammePractical InformationSponsors Overview Course Overview Liquid biopsies have the advantage of being largely non invasive and providing a vast amount of information for the detection and monitoring of diseases such as cancer This course will provide an overview in the several techniques to detect and analyse circulating tumour cells CTCs cell free tumor DNA ctDNA miRNA in liquid biopsies cell free tumour RNA ctRNA and proteins Participants will be introduced to all aspects ranging from proper sampling through error free sequencing to data analysis Additional lectures will cover extracellular vesicles and clinical aspects using liquid biopsies especially in the field of cancer diagnostics Please note that all participants are expected to engage in all sessions Audience This course targets early career scientists entering the field of liquid biopsy analysis and wanting to learn about the benefits and limitations of different approaches Modules Resources Ultra sensitive mutation detection using sequencing Single cell analysis in liquid biopsies Digital PCR applications in the liquid biopsy workflow Protein analysis in liquid biopsies miRNA analysis in liquid biopsies Hands on data analysis and interpretations Learning Outcomes Participants will receive an overview of various workflows in liquid biopsies from sample preparation to data analysis The course provides and overview of the current methods Whereby a strong focus will be on experimental design best practices pitfalls as well as dos and don ts After the course participants should be able to assess the best methods for their application as well as design their experiment Participant Commitment The virtual course will start on Monday 27 September with an onboarding session and access to the pre recorded lectures and pre course study materials exercises assignments etc It will continue on Friday 8 October with the regular programme The course will start on Friday 8 October and after a break over the weekend will continue on Monday 11 October with the regular programme The virtual course includes recorded lectures interactive discussion sessions online practicals hands on exercises student presentations and networking Full time attendance is required for the course duration Selected participants will have access to the recorded talks 2 weeks before the start of the event Please note that watching the recordings prior to the start of the course is required and will take approximately 15 hours Information on the live stream and access to the virtual course platform will be provided shortly before the start of the event Access to the recorded talks and the virtual course platform will be available for 2 weeks after the end of the event What past participants say about the course The Liquid Biopsy course gave me plenty of new insights for different applications of the technique in cancer I learned new techniques discussed my project with top peers and met a lot of highly motivated young professionals I incorporated the learned applications in my research and this really improved my current project Aleksei Tikhonov Engelhardt Institute of Molecular Biology RAS Russian Federation Speakers and Trainers Joerg Bantin Bio Rad Germany Marco Bianchi Bio Rad Germany Lei Chen Uppsala University Sweden Anders Edsj Sk ne University Hospital Sweden Stefan Filges Sahlgrenska Academy at University of Gothenburg Sweden Amin Forootan MultiD Analyses AB Sweden Tony E Godfrey Boston University School of Medicine USA An Hendrix Ghent University Belgium Andrea Huxhold QIAGEN Germany Romy Kirsten National Center for Tumor Diseases NCT Heidelberg Germany Mikael Kubista Institute of Biotechnology and TATAA Biocenter Czech Republic Ulf Landegren Uppsala University Sweden Manuel Marceliano Luna Santa Mar a Sahlgrenska Academy at University of Gothenburg Sweden Tobias sterlund Sahlgrenska Academy at University of Gothenburg Sweden Michael Pfaffl Technical University of Munich Germany Beata Ramasz EMBL Heidelberg Germany Pia Scheu Bio Rad Germany Anders St hlberg Sahlgrenska Academy at University of Gothenburg Sweden Val rie Taly Paris Descartes University France Eddy van Collenburg Bio Rad Germany Scientific Organisers Vladimir Benes EMBL Heidelberg Germany Anders St hlberg Sahlgrenska Academy at University of Gothenburg Sweden Course Organisers Maria Mercedes Bacadare Goitia Course and Conference Manager EMBL Heidelberg Germany Irena Provaznikova Training Lab Technician EMBL Heidelberg Germany Nathalie Sneider Course and Conference Officer EMBL Heidelberg Germany Programme Got something to say Tweet it with EMBLLiquidBiopsies The virtual course will start on Monday 27 September with an onboarding session and access to the pre recorded talks from invited speakers and trainers The course will continue on Friday 8 October with the regular programme Participants will be required to view the pre recorded talks 15 h prior to the main start of the course on Friday 8 October During the five day course duration full time attendance is required All times in the programme below are shown as the time in Europe Berlin To find out the equivalent time zone in your location enter Berlin the programme time and date along with your city into the Time Zone Converter Day 0 Monday 27 September 2021 TimeSpeaker13 00 15 00Onboarding15 00End of Day 0 Continued access to networking and discussion platform pre recorded lectures and course materials on eCampus Day 1 Friday 8 October 2021 TimeSpeakerPre analytical day13 00 13 15Welcome house notes and course overview13 15 14 30Icebreaker activity flash talks 14 30 14 45Break14 45 15 30Interactive Lecture Background lecture with live Q AAnders St hlberg Sahlgrenska Academy at University of Gothenburg Sweden15 30 15 45Break15 45 16 30Live Q A session Based on pre recorded talksRomy Kirsten National Center for Tumor Diseases NCT Heidelberg GermanyAnders St hlberg Sahlgrenska Academy at University of Gothenburg SwedenAndrea Huxhold QIAGEN Germany16 30 16 45Break16 45 17 45Student presentations17 45 18 00Break18 00 18 30Speed Networking 18 30End of Day 1 Continued access to networking and discussion platform pre recorded lectures and course materials on eCampus Day 2 Monday 11 October 2021 TimeSpeakerSession Single Cell day12 45 13 00Overview of the day13 00 13 30Group discussion from Pre analytical day13 30 14 30Live Q A session based on pre recorded talks Single Cell analysisBeata Ramasz EMBL Heidelberg GermanyAnders St hlberg Sahlgrenska Academy at University of Gothenburg Sweden14 30 14 45Break14 45 15 45Interactive practical session Single cell workflowBeata Ramasz EMBL Heidelberg Germany15 45 16 00Break16 00 17 00Student presentations17 00 17 15Break17 15 17 45Networking activity Online Pictionary17 45End of Day 2 Continued access to networking and discussion platform pre recorded lectures and course materials on eCampus Day 3 Tuesday 12 October 2021 TimeSpeakerSession ddPCR and miRNA day12 45 13 00Overview of the day13 00 13 30Group discussion from Single Cell day13 30 14 30Live Q A session to pre recorded talk practicals session Digital PCRPia Scheu Bio Rad GermanyMarco Bianchi Bio Rad GermanyEddy van Collenburg Bio Rad Germany14 30 14 45Break14 45 15 45Interactive practical session miRNA workflowManuel Marceliano Luna Santa Mar a Sahlgrenska Academy at University of Gothenburg Sweden15 45 16 15Networking break16 15 17 15Interactive practical session miRNA analysisMikael Kubista Institute of Biotechnology and TATAA Biocenter Czech Republic17 15 17 30Break17 30 18 30Student presentations18 30End of Day 3 Continued access to networking and discussion platform pre recorded lectures and course materials on eCampus Day 4 Wednesday 13 October 2021 TimeSpeakerSession Sequencing day12 45 13 00Overview of the day13 00 13 30Group discussion from ddPCR and miRNA day13 30 14 30Live Q A session to pre recorded talksAn Hendrix Ghent University BelgiumTony E Godfrey Boston University School of Medicine USAMichael Pfaffl Technical University of Munich Germany14 30 14 45Break14 45 16 45Interactive practical session SIMSen SeqStefan Filges Sahlgrenska Academy at University of Gothenburg Sweden16 45 17 00Break17 00 18 00Student presentations18 00End of Day 4 Continued access to networking and discussion platform pre recorded lectures and course materials on eCampus Day 5 Thursday 14 October 2021 TimeSpeakerSession Protein day12 45 13 00Overview of the day13 00 13 30Group discussion from Sequencing day13 30 15 30Interactive practical session Data Analysis of SIMSen Seq dataStefan Filges Sahlgrenska Academy at University of Gothenburg SwedenManuel Marceliano Luna Santa Mar a Sahlgrenska Academy at University of Gothenburg SwedenTobias sterlund Sahlgrenska Academy at University of Gothenburg Sweden15 30 15 45Break15 45 16 30Live Q A session based on pre recorded talksLei Chen Uppsala University SwedenUlf Landegren Uppsala University Sweden16 30 16 45Break16 45 17 45Interactive practical session PEA assayLei Chen Uppsala University Sweden17 45 18 00Break18 00 18 30Networking activity Bar mixer18 30End of Day 5 Continued access to networking and discussion platform pre recorded lectures and course materials on eCampus Day 6 Friday 15 October 2021 TimeSpeaker12 45 13 00Overview of the day13 00 13 30Group discussion from Data Analysis and Protein dayAnders St hlberg Sahlgrenska Academy at University of Gothenburg Sweden13 30 14 15Live talk with Q A sessionVal rie Taly Paris Descartes University France14 15 14 45Live Q A session based on pre recorded talksAnders Edsj Sk ne University Hospital SwedenToni E Godfrey Boston University School of Medicine USA14 45 14 50Group picture14 50 15 00Break15 00 16 00Meet the experts in Breakout Rooms 16 00 16 30Closing remarks and farewell16 30End of the Course Practical Information Registration Fees and Motivation Letter The course is limited to 16 participants For selection purposes please note that your application will not be considered without a letter of motivation Registration Registration Fees include admission and all course materials Academia295 EuroPhD Student295 EuroIndustry520 Euro Confirmation and Payment The registration fee should be paid only after acceptance to the course The results will be announced approximately 2 3 weeks after the application deadline Motivation Letter Submission After you have logged in and successfully registered you will receive an email asking you to submit your motivation letter Click on the link provided and enter your motivation letter in the text box provided Alternatively you can submit your motivation letter by clicking on the link on the confirmation page directly after registering Instructions Include your relevant skills experience and qualifications showing why you would be suitable for the course Explain why you would like to attend including what you can contribute and how you think you will benefit from the course Please note Motivation letter length The maximum limit of 2000 characters ca 200 words refers to manually typed text spaces included Free field text length The maximum characters for your answers in the free field text boxes is 255 spaces included Text only If you copy paste the text hidden formatting might still be included and you will be informed that your text exceeds the character limit We recommend either saving your text as text only in your editor or Email programme ORcopy pasting it into Notepad and then onto the website Symbols If you have special symbols in your text make sure you are using Unicode characters otherwise these will not be recognised by the tool Further Details For further information about registration and motivation letter submission please refer to the FAQ page Financial Assistance Financial Assistance Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of both registration fee waivers and travel grants Availability is limited to events in Heidelberg and will be indicated during the abstract or motivation letter submission process A list of external funding opportunities can be found here and information on attending a conference as an event reporter here Onsite events Your place in the meeting is only confirmed by paying the registration fee which is mandatory even when receiving a fee waiver Virtual events You are not required to pre pay the registration fee to be selected for a fee waiver for a virtual meeting EMBO childcare grants are available for EMBO Practical Courses and Workshops at all EMBL sites Courses Registration Fee Waiver The fee waiver will cover the registration sum that you have paid to attend the course Boehringer Ingelheim Fonds Travel Grant Applies to selected courses only Availability will be indicated during the abstract or motivation letter submission process This grant covers costs related to your attendance to the course registration travel and accommodation costs The grant is restricted to PhD students and postdocs who conduct basic biomedical research Whether you are eligible to apply for a travel grant depends on when you received your university entrance qualification e g Abitur A Levels High School Diploma Final State Examination for PhD and MD students as well as graduates the university entrance qualification must not have been obtained more than 11 years ago at the time of the envisaged course for postdocs the university entrance qualification must not have been obtained more than 13 years ago at the time of the envisaged course Further details For further information about financial assistance please refer to the FAQ page Technical Requirements Technical Requirements Below you will find the software and technical requirements for this course You will need admin rights to be able to install the software on your computer and we recommend you try this before the course If you do not have admin rights please contact your technical support team in advance to make sure the software can be installed Additional Software The EMBL eCampus learning platform will be used to collaborate communicate and network with all of the course participants All participants will receive information on how to join shortly before the course We recommend using Chrome Safari or Mozilla Firefox browsers for eCampus Zoom will be used for the live talks and Q A sessions More information will be provided closer to the start of the course Other Information While using the software during the course please make sure you have nothing else using your bandwidth We recommend using a wired connection Virtual Participation Guidelines Guidelines Please do Use the event specific hashtag EMBLLiquidBiopsies during the event for any related tweetsTweet unless the speaker specifically says otherwiseBe mindful of unpublished dataBe respectful in tone and content Please don t Share your login details to eCampus with othersBroadcast the conference to unregistered participantsCapture transmit or redistribute data presented at the meeting unless presenter gives explicit consentUse offensive language in your postsEngage in rudeness or personal attacks Additional information can be found in our Code of Conduct Sponsors Media Partner Sponsorship Opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage...

Vladimir Benes, Anders Ståhlberg

EMBL Course

Virtual

6 October 2021

Open access: Data sharing and submission

Edit

October 06, 2021 15:302021WebinarVirtual

Description This webinar will be the first of our series of webinars on the topic of open access In this webinar we will discuss the importance of sharing research data and illustrate how EMBL EBI provides some of the infrastructure to allow data sharing Our first speaker Tony Burdett will talk about the importance of FAIR data He ll discuss the common misconceptions around FAIR data and open data and talk about some of the impact GDPR can have on data sharing In this section he will explain the role that metadata and standards play in data sharing and submissions to large public repositories like those at EMBL EBI The second speaker Birgit Meldal works as a biocurator for IntAct and Complex Portal resources for molecular interaction and protein complexes In her part she will illustrate how to submit data to these resources and will discuss the advantages and challenges of providing open access data...

Tony Burdett, Birgit Meldal

Virtual

5 October - 8 October 2021

Seeing is Believing: Imaging the Molecular Processes of Life

Edit

The future of preprint peer review

Edit

September 23, 2021 10:002021WebinarVirtual

Description Public review of preprints is rapidly gaining momentum with expert reviews commentary and recommendations shared on various preprint platforms In this webinar we look at the current state of preprint peer review and share our thoughts on the future of the preprint review process Our first speaker Tatiana Giraud a CNRS senior scientist at the University Paris Saclay Professor at the Ecole Polytechnque and College de France member of the French Academy of Science and the Peer Community In PCI association will present the PCI initiative and share her experience reviewing and recommending preprints her involvement with the PCI initiative and her outlook on preprint peer review Next we will hear from Nonia Pariente the Editor in Chief of PLOS Biology will discuss how editors interact with preprints across PLOS with some emphasis on PLOS Biology summarising the results of the PLOS preprint commenting pilot in which editors looked at preprint comments during the peer review process as well as PLOS es interactions with preprint review initiatives such as Review Commons and Peer Community In Following on Thomas Lemberger Deputy Head of Scientific Publications at EMBO will present some of the data obtained from running the preprint peer review platform Review Commons These results will be discussed in the broader context of a cultural shift in the practice of peer review and the role of refereed preprints in the early dissemination of peer reviewed research Next Paul Shannon Head of Technology at eLife will introduce Sciety a new web based tool to enable scholars to discover preprint content via a network of curation and evaluation output Paul will talk about how Sciety brings peer review highlights automated screening and recommendation of preprints together from 16 diverse groups of scientists while allowing individuals to curate and share lists of preprints to help others navigate the preprint landscape Finally Maria Levchenko Europe PMC Community Manager will talk about Europe PMC as a unified platform to discover preprints and linked preprint resources such as community peer reviews Maria will also look at ways to filter preprints in the absence of journal titles and the role that aggregators like Europe PMC can play to prevent information overload About the speakers Tatiana Giraud is a CNRS senior scientist at the University Paris Saclay Professor at the Ecole Polytechnque and College de France and member of the French Academy of Science Tatiana Giraud is an evolutionary biologist with broad scientific interests She has contributed to the understanding of speciation pathogen virulence host pathogen coevolution biological invasions evolution of cooperation by kin selection mating systems apple tree and cheese fungi domestication using theory experiments population genetics and genomics Tatiana Giraud is also a member of the Peer Community In PCI association and recommender for PCI Evolutionary Biology PCI Genomics and PCI Ecology Nonia Pariente is Editor in Chief of the not for profit open access journal PLOS Biology Nonia trained as a virologist receiving a PhD from the Autonoma University of Madrid followed by postdoctoral research at the University of California in Los Angeles In 2007 Nonia joined the EMBO reports editorial team and over 8 years held various editorial roles joining the launch team of Nature Microbiology in 2015 After handling microbiology on and off at Nature for two years Nonia became Chief Editor of Nature Microbiology in 2019 and joined PLOS as PLOS Biology Editor in Chief in early 2020 Thomas Lemberger is Deputy Head of Scientific Publications at EMBO embo org in Heidelberg Germany Trained as a molecular biologist Thomas received his PhD at the University of Lausanne Switzerland He joined EMBO as scientific editor to launch the open access journal Molecular Systems Biology msb embopress org He was Chief Editor of the journal for more than 10 years Thomas is currently responsible for data and technology at EMBO Press He heads the SourceData project sourcedata embo org developed the Early Evidence Base site eeb embo org and leads the development of the peer review platform Review Commons reviewcommons org at EMBO Paul Shannon is the Head of Technology at eLife responsible for technology strategy and delivery ensuring the team are committed to openness in the products they produce to encourage broad change across the research communication landscape He is currently leading the development of Sciety a new web based tool to enable scholars to discover preprint content via a network of curation and evaluation output Maria Levchenko is a Community Manager for Europe PMC an open literature database for life sciences developed by the European Bioinformatics Institute EMBL EBI Europe PMC indexes over 300 000 preprints abstracts and full text COVID 19 preprints from 20 life sciences preprint servers alongside published journal articles Before joining Europe PMC Maria obtained a PhD in Biochemistry from Georg August University in Goettingen Germany and has worked with the European Research Council ERC Executive Agency Maria is passionate about innovative solutions in scholarly communications that help the research community to advance scientific knowledge...

Nonia Pariente, Tatiana Giraud, Maria Levchenko, Paul Shannon, Thomas Lemberger

Virtual

22 September 2021

Retrieving biological data from EMBL-EBI resources using Dbfetch

Edit

September 22, 2021 15:302021WebinarVirtual

Description Dbfetch provides a single point of access to retrieve biological data entries from various databases at EMBL EBI This webinar will provide a brief overview of the Dbfetch service and illustrate various output formats of data retrievable via Dbfetch In addition to the web browser based applications of Dbfetch we will also demonstrate accessing Dbfetch using the API...

Nandana Madhusoodanan, Fabio Madeira

Virtual

16 September 2021

Introduction to PerMedCoE: Exascale-ready cell-level simulations for European Personalised Medicine

Edit

September 16, 2021 15:302021WebinarVirtual

Description Personalised Medicine PerMed opens unexplored frontiers to treat diseases at the individual level combining clinical and omics information However the performances of the current simulation software are still insufficient to tackle medical problems such as tumour evolution or patient specific treatments The challenge is to develop a sustainable roadmap to scale up the essential software for the cell level simulation to the new European HPC Exascale systems Simulation of cellular mechanistic models are essential for the translation of omic data to medical relevant actions and these should be accessible to the end users in the appropriate environment of the PerMed specific big confidential data The goal of PerMedCoE is to provide an efficient and sustainable entry point to the HPC Exascale upgraded methodology to translate omics analyses into actionable models of cellular functions of medical relevance It will accomplish so by Optimising four core applications for cell level simulations to the new pre exascale platforms Integrating PerMed into the new European HPC Exascale ecosystem by offering access to HPC Exascale adapted and optimised software Running a comprehensive set of PerMed use cases including simulations of tumour evolution and drug combinations for cancer treatment Building the basis for the sustainability of the PerMedCoE by coordinating PerMed and HPC communities and reaching out to industrial and academic end users with use cases training expertise and best practices The PerMedCoE cell level simulations will fill the gap between the molecular and organ level simulations from the other CoEs with which this project is aligned at different levels It will connect method developers with HPC HTC and HPDA experts Finally PerMedCoE will work with biomedical consortia and pre exascale infrastructures including a substantial co design effort About the speaker Alfonso Valencia is a Spanish biologist ICREA Professor current director of the Life Sciences department at Barcelona Supercomputing Center BSC and of Spanish National Bioinformatics Institute INB ISCIII He received his PhD in molecular biology in 1988 from the Autonomous University of Madrid From 1989 to 1994 he was a Postdoctoral Fellow in the laboratory of Chris Sander at the European Molecular Biology Laboratory EMBL in Heidelberg studying the evolution of protein function using sequence and structure based approaches In 1994 Valencia formed the Protein Design Group at the Spanish National Center for Biotechnology CNB He was leader of the Structural and Computational Biology Group at Spanish National Cancer Research Center CNIO From 2015 2018 he was President of the International Society for Computational Biology ISCB As computational biologist the focus of his work is the mechanistic understanding of biological systems including cancer and other diseases with a combination of Bioinformatics Network Biology and Machine Learning approaches His group has developed systems in the areas of protein structure prediction protein interactions and protein networks systems biology text and data mining with applications in epigenetic cancer genomics and disease comorbidity All these activities converge into the general topic of Personalised Medicine with particular interest in the interface with Artificial intelligence and High Performance Computing...

Alfonso Valencia

Virtual

15 September 2021

Getting started with the Open Targets Platform GraphQL API

Edit

September 15, 2021 15:302021WebinarVirtual

Description The Open Targets Platform is a comprehensive research tool that supports systematic identification and prioritisation of potential therapeutic drug targets By integrating publicly available datasets along with data generated by the Open Targets consortium the Platform builds and scores target disease associations Users can also explore relevant annotation information about targets diseases phenotypes and drugs as well as their most relevant relationships This webinar will provide an overview of the GraphQL API that powers the Open Targets Platform The API provides multiple endpoints that support language agnostic queries for a single entity or target disease association Users can also browse the schema to see available API fields and run sample queries using the API playground During the webinar participants will have access to interactive walkthroughs and API queries that can be run directly in their browser There will also be sample Python and R scripts that they can run to test different endpoints...

Andrew Hercules, Helena Cornu

Virtual

15 September - 17 September 2021

Multiomics to Mechanisms: Challenges in Data Integration

Edit

September 15, 2021 00:002021ConferenceVirtual

Description OverviewSpeakersProgrammePractical InformationSponsorsAbout Overview EMBO and EMBL are committed to sharing research advances and sustaining scientific interaction throughout the coronavirus pandemic We are delighted to announce that the conference is going virtual and invite you to join us online The virtual conference includes talks from invited speakers short talk presenters online group discussions and networking opportunities Symposium Overview The current speed at which high throughput data are produced and the growing number of studies that use not only one but multiple omics technologies on the same samples offers tremendous opportunities for enhancing our molecular understanding of biological systems One of the biggest challenges in the era of multiomics is the integration and interpretation of the diverse large scale omics data in a way that provides biological insights This requires the development of statistical mathematical and computational tools and equally important experimental strategies to follow up on hypotheses generated by large scale data Together these computational and experimental tools will enable us to address novel questions and identify biological mechanisms This is the third in series of EMBL EMBO symposia focusing on challenges and opportunities in data integration Our goal is to provide a platform for discussing and presenting strategies for multiomics data integration that go beyond descriptive analyses and aim towards mechanistic biological interpretation For this we are inviting scientists from different fields that share their enthusiasm for integrating multi modal data to understand biological systems Traditionally the audience of the meeting has been very diverse in terms of biology yet very united in their interest in discussing about how to integrate and learn from data Presenters are therefore asked to specifically highlight the integrative aspect of their work and how it helped in understanding biology Session Topics Novel high throughput technologiesStatistical methods for data integrationComputational tools for data integrationMultiomics in single cellsApplications of multiomicsApplications of metabolomicsApplications of proteomicsApplications of genomicsMechanistic studies to follow up omics studies Speakers Ariel Amir Harvard University USA Christina Curtis Stanford University USA Ignacia Echeverria Riesco University of California San Francisco USA Stacey Finley University of Southern California USA Thomas H fer German Cancer Research Center Germany KC Huang Stanford University USA Edda Klipp Humboldt Universit t zu Berlin Germany Tanja Kortemme University of California San Francisco USA Ivan Marazzi Icahn School of Medicine at Mount Sinai USA Kyung Min Noh EMBL Heidelberg Germany Evangelia Petsalaki EMBL EBI Hinxton UK Katie Pollard Gladstone Institutes and University of California San Francisco USA Eran Segal Weizmann Institute of Science Israel Bas Teusink Vrije Universiteit Amsterdam The Netherlands Juanma Vaquerizas MRC London Institute of Medical Sciences UK Christine Vogel New York University USA Scientific Organisers Nevan Krogan University of California San Francisco USA Uwe Sauer ETH Z rich Switzerland Judith Zaugg EMBL Heidelberg Germany Conference Officers Nathalie Sneider EMBL Heidelberg Germany Maria Mercedes Bacadare Goitia EMBL Heidelberg Germany Programme Got something to say Tweet it EESOmics The virtual conference includes live streamed invited speaker talks and live streamed selected short talks with live Q A sessions after each talk as well a panel discussion each day and meet the speaker sessions All digital poster presenters are encouraged to upload a recorded flash talk or narration with their digital poster and to schedule video calls during poster session times Information on the live stream and access to the discussion platform and digital posters will be provided 1 week before the start of the event Pre recorded talks 160 minutes in total will be made available 1 week before the start of the conference Presenters of pre recorded talks will be attending the Meet the Pre recorded Short Talk Speaker sessions that will take place in parallel with the Day 1 and Day 2 Poster Sessions Please watch the pre recorded talks beforehand so that you can ask your questions discuss the talk Access to the recorded talks will be available for 2 weeks after the end of the event All times in the programme below are shown as the time in Europe Berlin To find out the equivalent time zone in your location enter Berlin the programme time and date along with your city into the Time Zone Converter Day 1 Wednesday 15 September 2021 TimeSpeaker15 00 15 10 Opening remarks 15 10 18 20Session 1Chairs Evangelia Petsalaki and Judith Zaugg15 10 15 35Dissecting the regulation of hematopoiesis by lineage tracing and single cell omicsThomas H fer German Cancer Research Center GermanyAVAILABLE ON DEMAND AFTER LIVE STREAM15 35 15 50High throughput metabolome profiling predicts novel TOR signaling related genesDuncan Holbrook Smith ETH Z rich SwitzerlandAVAILABLE ON DEMAND AFTER LIVE STREAM15 50 16 15The Ups and Downs of Protein Expression RegulationChristine Vogel New York University USAAVAILABLE ON DEMAND AFTER LIVE STREAM16 15 16 30Multiomics landscape of the ageing human mesenchymal stromal cellsMang Ching Lai EMBL Heidelberg GermanyAVAILABLE ON DEMAND AFTER LIVE STREAM16 30 16 45Break16 45 17 10To bin or not to bin analyzing single cell growth dataAriel Amir Harvard University USAAVAILABLE ON DEMAND AFTER LIVE STREAM17 10 17 25Signature Regulatory Clustering SiRCle model to understand cancer regulation through semi supervised integrationChristina Schmidt University of Cambridge UKAVAILABLE ON DEMAND AFTER LIVE STREAM17 25 17 50Sequence structure function modeling for DNAKatie Pollard Gladstone Institutes and University of California San Francisco USAAVAILABLE ON DEMAND AFTER LIVE STREAM17 50 18 15Genotype to phenotype mapping of tumorigenesis at single cell resolutionChristina Curtis Stanford University USAAVAILABLE ON DEMAND AFTER LIVE STREAM18 15 18 50Break18 50 19 50Virtual Poster Session 1 A L and Meet the Pre recorded Short Talk Speakers A M 19 50 20 35Panel Discussion Day 1Chairs Evangelia Petsalaki and Judith ZauggPanelistsAriel Amir Harvard University USAChristina Curtis Stanford University USAThomas H fer German Cancer Research Center GermanyKatie Pollard Gladstone Institutes and University of California San Francisco USAChristine Vogel New York University USA20 35 20 40Transition to Meet the Speakers Day 1 20 40 21 10Meet the Speakers Day 1Ariel Amir Christina Curtis Thomas H fer Katie Pollard Christine Vogel and short talk speakers Duncan Holbrook Smith Mang Ching Lai Christina Schmidt21 10 21 15Transition over to Virtual Speed Networking21 15 22 00Social programme Virtual speed networking Digital posters and pre recorded talks as well as discussion channels will be available for registered participants throughout the whole virtual meeting Day 2 Thursday 16 September 2021 TimeSpeaker14 30 15 00Social programme Meet other participants in the Social Lounge and chat ahead of the day s talks link available in the conference platform 15 00 18 05Session 2Chairs Edda Klipp and Nevan Krogan15 00 15 25 Chromatin conformation during early embryonic developmentJuanma Vaquerizas MRC London Institute of Medical Sciences UKAVAILABLE ON DEMAND AFTER LIVE STREAM15 25 15 40The pathobiology of Mycobacterium abscessus revealed through phenogenomic analysisLucas Boeck University of Basel SwitzerlandAVAILABLE ON DEMAND AFTER LIVE STREAM15 40 16 05Harnessing big data for personalized medicineEran Segal Weizmann Institute of Science IsraelAVAILABLE ON DEMAND AFTER LIVE STREAM16 05 16 20Computational pharmacogenomics identifies synergistic statin compound combinations that target the mevalonate pathway for breast cancer treatmentDeena Gendoo University of Birmingham UKAVAILABLE ON DEMAND AFTER LIVE STREAM16 20 16 35Break16 35 17 00Incorporating proteome constraints in genome scale metabolic modelsBas Teusink Vrije Universiteit Amsterdam The NetherlandsAVAILABLE ON DEMAND AFTER LIVE STREAM17 00 17 15Uncovering molecular aging trajectories in budding yeast through multidimensional proteomicsMario Leutert University of Washington USAAVAILABLE ON DEMAND AFTER LIVE STREAM17 15 17 40Mechanistic insights into functional effects of point mutations at the systems levelTanja Kortemme University of California San Francisco USAAVAILABLE ON DEMAND AFTER LIVE STREAM17 40 18 05Integration of constraint based models and metabolomics to elucidate tumor stromal crosstalk in colorectal cancerStacey Finley University of Southern California San Francisco USAAVAILABLE ON DEMAND AFTER LIVE STREAM18 05 18 35Break18 35 19 35Virtual Poster Session 2 M Z and Meet the Pre recorded Short Talk Speakers N Z 19 35 20 20Panel Discussion Day 2Chairs Edda Klipp and Nevan KroganPanelists Stacey Finley University of Southern California San Francisco USATanja Kortemme University of California San Francisco USAJuanma Vaquerizas Max Planck Institute for Molecular Biomedicine Muenster Germany20 20 20 25Transition to Meet the Speakers Day 220 25 20 55Meet the Speakers Day 2Stacey Finley Tanja Kortemme Juanma Vaquerizas and short talk speakers Lucas Boeck Deena Gendoo Mario Leutert20 55 21 00Transition over to Living Room Concert followed by Bar Mixer 21 00 22 00Social programme Living Room Concert with Lazy Fur 30 minutes followed by Bar Mixer 30 minutes Digital posters and pre recorded talks as well as discussion channels will be available for registered participants throughout the whole virtual meeting Day 3 Friday 17 September 2021 TimeSpeaker15 00 18 40Session 3Chairs Thomas H fer and Uwe Sauer15 00 15 25 Identification of phenotype specific networks from paired gene expression cell shape imaging dataEvangelia Petsalaki EMBL EBI Hinxton UKAVAILABLE ON DEMAND AFTER LIVE STREAM15 25 15 40Integrated multi omic analysis of a rare inborn error of metabolismPatrick Forny University Children s Hospital ZurichAVAILABLE ON DEMAND AFTER LIVE STREAM15 40 16 05Molecular function of chromatin regulators linked to neurodevelopmental disordersKyung Min Noh EMBL Heidelberg GermanyAVAILABLE ON DEMAND AFTER LIVE STREAM16 05 16 20 Break16 20 16 45Understanding a life integration of time resolved population and single cell data for a yeast cell from birth to divisionEdda Klipp Humboldt Universit t zu Berlin GermanyAVAILABLE ON DEMAND AFTER LIVE STREAM16 45 17 00Multi omics reveals clinically relevant proliferative drive associated with mTOR MYC OXPHOS activity in chronic lymphocytic leukemiaJunyan Lu EMBL Heidelberg GermanyAVAILABLE ON DEMAND AFTER LIVE STREAM17 00 17 25Combining genetics and proteomics data for integrative structure determinationIgnacia Echeverria Riesco University of California San Francisco USAAVAILABLE ON DEMAND AFTER LIVE STREAM17 25 17 35Break17 35 18 00Systematic investigation of gene function in gut bacteria using randomly barcoded transposon insertion librariesKC Huang Stanford University USAAVAILABLE ON DEMAND AFTER LIVE STREAM18 00 18 15Extracting Mechanistic Insight into SARS CoV 2 and Emerging Variants by Integrating Orthogonal Molecular DatasetsMehdi Bouhaddou QCRG University of California San Francisco USAAVAILABLE ON DEMAND AFTER LIVE STREAM18 15 18 40Chimeric genes neogenes and hybrid regulatory elements control infection and cell specificationIvan Marazzi Icahn School of Medicine at Mount Sinai USAAVAILABLE ON DEMAND AFTER LIVE STREAM18 40 19 10Break19 10 20 10Virtual Poster Session 3 All 20 10 20 55Panel Discussion Day 3 SpeakersChairs Thomas H fer and Uwe SauerPanelists Ignacia Echeverria Riesco University of California San Francisco USAKC Huang Stanford University USAEdda Klipp Humboldt Universit t zu Berlin GermanyIvan Marazzi Icahn School of Medicine at Mount Sinai USAKyung Min Noh EMBL Heidelberg GermanyEvangelia Petsalaki EMBL EBI Hinxton UKBas Teusink Vrije Universiteit Amsterdam The Netherlands20 55 21 00Transition to Meet the Speakers Day 321 00 21 30Meet the Speakers Day 3Ignacia Echeverria Riesco KC Huang Edda Klipp Ivan Marazzi Kyung Min Noh Evangelia Petsalaki Bas Teusink and short talk speakers Patrick Forny Junyan Lu Mehdi Bouhaddou21 30 21 35Transition over to Closing Remarks21 35 21 45Closing remarks and Poster Prizes Digital posters and pre recorded talks as well as discussion channels will be available for registered participants throughout the whole virtual meeting Practical Information Registration Fees and Abstract Submission Registration Fees include access to all of the talks digital poster sessions and online group discussions and help us cover our costs to run the event For further information please refer to the FAQ page Academia190 EuroPhD Student140 EuroIndustry240 EuroEMBL StaffIntranet access Accredited journalists may be eligible to register for a complimentary registration Registrants may be required to provide accreditation or equivalent proof of press membership after registration Please contact Maria Bacadare for more information Confirmation and Payment Registration will be on a first come first served basis Your place can only be confirmed after payment of the registration fee Types of payments accepted are international bank transfers and credit card payments Abstract submission Abstract submission for this conference is closed For enquiries about submitting a late abstract for a poster presentation please contact Nathalie Sneider Financial Assistance Registration Fee Waivers All academic and student registrants are invited to apply for a registration fee waiver provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO The registration fee waiver covers the registration sum that you have paid to attend the meeting Conference participants are not required to pre pay the registration fee to be selected for a fee waiver for a virtual meeting If you have already paid the registration fee and are awarded a fee waiver it will be reimbursed after the meeting Course participants are required to pay the course fee in advance which will then be reimbursed after the recipient has attended the course Childcare Grants For participants and speakers with childcare responsibilities there is the possibility to apply for a grant provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO to offset childcare costs incurred when participating at a virtual event Eligible costs include fees for a babysitter or childcare facility or travel costs for a care giver Please note that priority will be given to early stage researchers Costs will be reimbursed after the meeting only once a reimbursement form and original receipts have been received Attendance at the event is required in order to be eligible to receive the reimbursement In order to apply for this grant you must be registered by the abstract submission deadline Application Applications for financial assistance can be submitted via the submission portal for the submission of abstracts for conferences or the submission of motivation letters for courses by completing the Financial Assistance Application Section underneath the section for entering abstract motivation letter information The link to the portal can be found in the registration confirmation email that you will receive after registering for the conference or course For conferences if you are not submitting an abstract you can still apply for financial assistance in the submission portal by following the instructions here Note that priority will be given to those submitting an abstract to present at the conference In your application you will be asked to answer questions regarding your motivation for applying and for registration fee waivers the reasons why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application For some events applications for Childcare Grants will still be done by email Information about the grant will be sent out shortly after the abstract motivation letter deadline Please contact the event Conference Officer if you have any questions Selection The scientific organisers will select the recipients of registration fee waivers during the abstract selection process for conferences and the participant selection process for courses Results will be announced approximately 3 4 weeks before the event start date Selection results do not impact your admission to the meeting Registration fee waiver selection is based on your current work or study location your motivation for applying the reasons for needing financial support and the impact this event will have on your career Childcare grants are allocated based on career stage with priority given to early stage researchers Further details A list of external funding opportunities can be found here and information on attending a conference as an event reporter here For further information about financial assistance please refer to the FAQ page Virtual Participation Guidelines Guidelines Please do Use the event specific hashtag as communicated during the event for any related tweetsTweet unless the speaker specifically says otherwiseBe mindful of unpublished dataBe respectful in tone and content Please don t Share Slack live stream or poster session links with othersBroadcast the conference to unregistered participantsCapture transmit or redistribute data presented at the meeting unless presenter gives explicit consentUse offensive language in your postsEngage in rudeness or personal attacks Additional information can be found in our Code of Conduct Health and well being It is important to stay healthy and move around especially when you are attending an event virtually We have put together a few coffee break stretches and yoga videos in the events Slack workspace for you to enjoy during the event How to ask questions Questions during and after the talks can be asked in live streaming platform The chair moderates the questions and shares them with the speaker If time runs out or you think of a question later you can use Slack to ask your questions in the dedicated session channels or via direct message Time zone The programme is planned based on Central European Summer Time CEST unless otherwise stated As many virtual participants are attending from around the world we do our best to accomodate as many timezones as possible when creating the programme Please take your time zone into consideration when planning your attendance Virtual event platforms We are using a virtual event platform for this conference More information about the platform will be shared ahead of the conference Sponsors Media Partners Molecular Systems Biology an EMBO Press journal International Union of Biochemistry and Molecular Biology Open Biology a Royal Society journal Sponsorship Opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a Sponsorship Brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsoring embl de About EMBO EMBL Symposia promote scientific communication and collaboration in the European research area They provide scientists with a platform to discuss and exchange ideas on forward looking topics and new developments in the life sciences Topics emphasise upcoming developments and the interdisciplinary nature of related fields Jointly funded and organised by EMBO and EMBL and complementary to their respective courses workshops and conference programmes the symposia promote scientific communication and collaboration All symposia are held in the EMBL Advanced Training Centre ATC in Heidelberg Germany or virtually...

Nevan Krogan, Uwe Sauer, Judith Zaugg

EMBO | EMBL Symposium

Virtual

14 September - 16 September 2021

Virtual Ensembl REST-API Workshop, 14th-16th Sept

Edit

September 14, 2021 00:002021CourseVirtual

Description Work with Ensembl to master the Ensembl REST API and flexibly access genome wide data such as genes variants regulatory features homologues and alignments...

Ben Moore

Virtual

8 September 2021

How to interpret AlphaFold structures

Edit

September 08, 2021 15:302021WebinarVirtual

Description This webinar will introduce AlphaFold system for prediction and interpretation of protein structures This webinar is designed for experimental biologists who wish to understand the strengths and limitations of AlphaFold and use the models to guide their experimental studies In this webinar we will provide an overview for the AlphaFold method and statistics that can be used to understand the reliability of the models We will also introduce the AlphaFold Database which provides hundreds of thousands of ready made models across the tree of life as well as highlight the AlphaFold Open Source and Colab notebooks that can be used to generate structures of sequences not yet available within the AlphaFold Database We will conclude by demonstrating a range of use cases followed by a question and answer session with all the presenters...

Alex Bateman, Sameer Velankar, Kathryn Tunyasuvakool, Sergey Ovchinnikov, Pedro Beltrao, Bálint Mészáros

Virtual

7 September - 10 September 2021

Protein Synthesis and Translational Control

Edit

September 07, 2021 00:002021ConferenceVirtual

Description OverviewSpeakersProgrammePractical informationSponsors Overview Registered participants will receive an email with access to the virtual conference platform on Monday 30 August EMBL is committed to sharing research advances and sustaining scientific interaction throughout the coronavirus pandemic We are delighted to announce that this conference is going virtual and invite you to join us online Conference Overview The regulation of mRNA translation is a process required to maintain cell homeostasis and its malfunction can lead to disease In recent years advances in high throughput and microscopy methods have revealed findings that challenge hitherto established dogmas such as extensive translation in untranslated regions of a transcript pervasive initiation from non AUG codons heterogeneity and specialization of the ribosome or specialized roles for general translation factors The influence of epitranscriptomics and physical transitions in translation or the molecular mechanisms underlying ribosome quality control are just examples where rapid progress is impacting our view of translation It is also now clear that the mRNA is covered with RNA binding proteins RBPs that control its fate some of which have dual functions as enzymes revealing connections with metabolism that we still need to understand Thus translation cannot be seen anymore as an isolated process but as one highly connected with other steps of gene expression and finely dependent on cellular context Advance on these aspects will be featured as well as the role of translation regulation in diseases as diverse as cancer metabolic or neurological disorders Session Topics Translation initiationRibosome elongation terminationMetabolism and diseaseRNP complexesInterconnections and turnoverMethods and systems approaches This conference is partnered with Cold Spring Harbor Laboratory CSHL Speakers Keynote Speakers John Hershey University of California Davis USA Ulrike Kutay ETH Zurich Switzerland Julia Mahamid EMBL Heidelberg Germany Speakers and Session Chairs Marina Chekulaeva Max Delbr ck Center for Molecular Medicine Germany Jeff Coller Johns Hopkins School of Medicine USA David Gatfield University of Lausanne Switzerland Jody Puglisi Stanford University School of Medicine USA Sunnie R Thompson University of Alabama at Birmingham School of Medicin USA Anne Willis University of Cambridge UK Additional speakers will be selected from abstracts Scientific Organisers F tima Gebauer Centre for Genomic Regulation CRG Spain Matthias W Hentze EMBL Heidelberg Germany Jerry Pelletier McGill University Canada Christian Spahn Charit Berlin Germany Conference Organiser Raili Pall EMBL Heidelberg Germany Inna Boesselmann EMBL Heidelberg Germany Programme Programme Got something to say Tweet it EMBLProtein The virtual conference includes keynote lectures live streamed invited speakers and selected short talks and round table discussions All digital poster presenters are encouraged to upload a recorded flash talk or narration with their digital poster Information on the live stream and access to the discussion platform and digital posters will be provided 1 week before the start of the event Pre recorded talks 5h total will be made available 1 week before the start of the conference Presenters of pre recorded talks will be attending live roundtable discussion session Please watch the pre recorded talks before the respective session in order to be able to follow the discussion Access to the recorded talks will be available until 24 September 2021 All times in the programme below are shown as the time in Europe Berlin To find out the equivalent time zone in your location enter Berlin the programme time and date along with your city into the Time Zone Converter Day 1 Tuesday 7 September 2021 TimeSpeaker14 00 14 10Opening remarks by F tima GebauerAVAILABLE ON DEMAND AFTER LIVE STREAMVirtual Session 1 RNP Complexes Session Chair Marina Chekulaeva Max Delbr ck Center for Molecular Medicine Germany14 10 14 20Introduction by Session Chair 14 20 14 45RNA localisation and local translation in neurons Marina Chekulaeva Max Delbr ck Center for Molecular Medicine GermanyAVAILABLE ON DEMAND AFTER LIVE STREAM14 45 15 00Coupling of transcription with ribosome assembly and translation in real timeOlivier Duss EMBL Heidelberg GermanyAVAILABLE ON DEMAND AFTER LIVE STREAM15 00 15 15Revealing the host antiviral protein ZAP S as an inhibitor of SARS CoV 2 programmed ribosomal frameshiftingNeva Caliskan Helmholtz Institute for RNA based Infection Research GermanyAVAILABLE ON DEMAND AFTER LIVE STREAM15 15 15 20Transition technical setup and switch to the next session 15 20 15 30Break15 30 15 45An RNA binding switch drives ribosome biogenesis and tumourigenesis downstream of oncogenic KRASFaraz Mardakheh Barts Cancer Institute UKAVAILABLE ON DEMAND AFTER LIVE STREAM15 45 16 00Aminoacyl tRNA synthetases utilize tRNA related features on mRNAs to specifically bind and regulate their translationYoav Arava Technion Israel Institute of TechnologyAVAILABLE ON DEMAND AFTER LIVE STREAM16 00 16 15Pseudouridine modified tRNA fragments repress malignant protein synthesis and impact leukemogenesisSowndarya Muthukumar Lund University SwedenAVAILABLE ON DEMAND AFTER LIVE STREAM16 15 16 30RGG motif protein Sbp1 is required for Processing body P body disassemblyRaju Roy Indian Institute of Science IndiaAVAILABLE ON DEMAND AFTER LIVE STREAM16 30 16 35Transition technical setup and switch to the next session 16 35 16 45Break16 45 17 10Meet the speakers of Session 1 Marina Chekulaeva Olivier Duss Neva Caliskan Faraz Mardakheh Yoav Arava Sowndarya Muthukumar Raju Roy17 10 17 15Break17 15 17 45Roundtable Discussion with pre recorded talk presenters moderated by session chair Aindrila Chatterjee EMBL Heidelberg GermanyAndrea Graziadei Technical University of Berlin GermanyWenqian Hu Mayo Clinic USARainer Nikolay Charit University Medicine Berlin GermanyDiana Silvia Marina Ottoz Columbia University USAAVAILABLE ON DEMAND AFTER LIVE STREAM17 45 18 15Social break with networking opportunity18 15 19 00Keynote lectureGetting ready for translation ribosome synthesis in human cellsUlrike Kutay ETH Zurich Switzerland 19 00 19 45Keynote lectureVisualizing cellular translation landscapes at atomic detailJulia Mahamid EMBL Heidelberg Germany19 45 19 55Break19 55 20 50Keynote lectureThe History of Studies of Protein Synthesis and its RegulationJohn Hershey University of California Davis USAAVAILABLE ON DEMAND AFTER LIVE STREAM20 50 21 20Meet the Keynote Speakers Ulrike Kutay Julia Mahamid and John Hershey21 20 22 35Virtual Poster Session 1Topics RNP complexes and Translation Initiation meet the poster presenters live chats and video calls 22 35End of day 1 Digital posters recordings and discussion channels will be available for registered participants throughout the whole virtual conference as well as 1 week before and 2 weeks after Day 2 Wednesday 8 September 2021 TimeSpeakerVirtual Session 2 Metabolism and DiseaseSession Chair Anne Willis University of Cambridge UK14 00 14 10Introduction by Session Chair14 10 14 35Aberrant mRNA translation drives metabolic output to increase cell growth in Malignant Mesothelioma Anne Willis University of Cambridge UKAVAILABLE ON DEMAND AFTER LIVE STREAM14 35 14 50Dynamic m6A mRNA methylation directs translational control of TXNIP instigates abdominal aortic aneurysm formation in Apoe miceHaingo Hantelys Georgia State University USAAVAILABLE ON DEMAND AFTER LIVE STREAM14 50 15 05Acetylation activated RNA binding of Enolase 1 regulates Glycolysis and Embryonic Stem Cell DifferentiationIna Huppertz EMBL Heidelberg GermanyAVAILABLE ON DEMAND AFTER LIVE STREAM15 05 15 10Transition technical setup and switch to the next session 15 10 15 20Break15 20 15 35Investigating the roles of 4E BP1 in breast cancer metastasisPredrag Jovanovic Lady Davis Institute at the Jewish General Hospital CanadaAVAILABLE ON DEMAND AFTER LIVE STREAM15 35 15 50Rpl24Bst mutation suppresses colorectal cancer by promoting eEF2 phosphorylation via eEF2KJohn Knight CRUK Beatson Institute UKAVAILABLE ON DEMAND AFTER LIVE STREAM15 50 16 05Lung cancer cells require dihydrouridine synthase 2 to sustain levels of tRNACys and production of cysteine rich proteinsAustin Draycott Yale University USAAVAILABLE ON DEMAND AFTER LIVE STREAM16 05 16 20Ribosome collisions fuel a vicious cycle of proteotoxicity in Huntington s DiseaseRanen Aviner Stanford University USAAVAILABLE ON DEMAND AFTER LIVE STREAM16 20 16 25Transition technical setup and switch to the next session 16 25 16 35Break16 35 16 50RNA translation regulates intestinal stem cell identity via Zaka activationJoana Silva Netherlands Cancer Institute The NetherlandsAVAILABLE ON DEMAND AFTER LIVE STREAM16 50 17 05A functional analysis of mutations in DAZL identified in infertile patientsNicola Gray University of Edinburgh UKAVAILABLE ON DEMAND AFTER LIVE STREAM17 05 17 35Meet the speakers of Session 2 Anne Willis Haingo Hantelys Ina Huppertz Predrag Jovanovic John Knight Austin Draycott Ranen Aviner Joana Silva Nicola Gray17 35 17 45Break17 45 18 15Roundtable Discussion with pre recorded talk presenters moderated by session chair Anton Komar Cleveland State University USAAntje Ostareck Lederer University Hospital RWTH Aachen GermanyErin Ritchie The Center for Plant MolecularBiology ZMBP GermanyMayuresh Sarangdhar Bern University Hospital SwitzerlandPeter Todd University of Michigan USAAVAILABLE ON DEMAND AFTER LIVE STREAM18 15 18 45Social break with networking opportunityVirtual Session 3 Interconnections and Turnover Session Chair Jeff Coller Johns Hopkins School of Medicine USA18 45 18 55Introduction by Session Chair18 55 19 20Insights into the interconnections between mRNA translation and mRNA stability Jeff Coller Johns Hopkins School of Medicine USAAVAILABLE ON DEMAND AFTER LIVE STREAM19 20 19 35An alternative UPF1 isoform drives conditional remodeling of nonsense mediated mRNA decaySarah Fritz National Institutes of Health National Heart Lung and Blood Institute USAAVAILABLE ON DEMAND AFTER LIVE STREAM19 35 19 50Cell specific control of gene expression through interactions of ARE binding proteins and microRNAsCourtney Jungers Washington University in St Louis USAAVAILABLE ON DEMAND AFTER LIVE STREAM19 50 19 55Transition technical setup and switch to the next session 19 55 20 05Break20 05 20 20Human SMG6 interacts with the 80S ribosome via its unstructured N terminal domainNina Kl y University of Bern SwitzerlandAVAILABLE ON DEMAND AFTER LIVE STREAM20 20 20 35Timed global reorganization of protein synthesis during neocortex neurogenesis at single codon resolutionMatthew Kraushar Max Planck Institute for Molecular Genetics GermanyAVAILABLE ON DEMAND AFTER LIVE STREAM20 35 20 50Unrecycled 40S initiated mRNA decay couples translation and piRNA productionXin Li University of Rochester USAAVAILABLE ON DEMAND AFTER LIVE STREAM20 50 21 05Molecular mechanisms of EDF1 mediated JUN signaling in response to ribotoxic stressNiladri Sinha Johns Hopkins Medical Institute USAAVAILABLE ON DEMAND AFTER LIVE STREAM21 05 21 10Transition technical setup and switch to the next session 21 10 21 20Break21 20 21 45Meet the speakers of Session 3 Jeff Coller Sarah Fritz Courtney Jungers Nina Kl y Matthew Kraushar Xin Li Niladri Sinha21 45 21 50Break21 50 22 20Roundtable Discussion with pre recorded talk presenters moderated by session chair Hagit Bar Yosef Technion Israel Institute of Technology IsraelSusanne Huch Karolinska Institutet SwedenTatsuaki Kurata Lund University SwedenShetty Sunil University of Basel SwitzerlandDavid Young National Institute of Diabetes and Digestive and Kidney Diseases USAAVAILABLE ON DEMAND AFTER LIVE STREAM22 20End of day 2 Digital posters recordings and discussion channels will be available for registered participants throughout the whole virtual conference as well as 1 week before and 2 weeks after Day 3 Thursday 9 September 2021 TimeSpeakerVirtual Session 4 Translation Initiation Session Chair Sunnie R Thompson University of Alabama at Birmingham School of Medicine USA14 00 14 10Introduction by Session Chair14 10 14 35The role of eS25 in cellular homeostasis and 40S binding by internal ribosome entry sitesSunnie R Thompson University of Alabama at Birmingham School of Medicine USAAVAILABLE ON DEMAND AFTER LIVE STREAM14 35 14 50Single molecule dynamics of early eukaryotic translation initiation Se n O Leary University of California Riverside USAAVAILABLE ON DEMAND AFTER LIVE STREAM14 50 15 05eIF1 eIF4G1 inhibitors uncover alternative path of translation activation of stress response genes via enhanced ribosome loading and 5 UTR translation Urmila Sehrawat Weizmann Institute of Science IsraelAVAILABLE ON DEMAND AFTER LIVE STREAM15 05 15 10Transition technical setup and switch to the next session 15 10 15 20Break15 20 15 35eIF4A1 unwinding activity is RNA sequence specifically deployed through eIF4A1 multimerisation to facilitate translation of mRNAs with local repressive RNA structure Tobias Schmidt CRUK Beatson Institute UKAVAILABLE ON DEMAND AFTER LIVE STREAM15 35 15 50A specific eIF4A paralog facilitates LARP1 mediated translation repression during mTORC1 inhibition Yuichi Shichino RIKEN JapanAVAILABLE ON DEMAND AFTER LIVE STREAM15 50 16 05Molecular basis of mRNA Kozak sequence recognition on the ribosome Bruno Klaholz Centre for Integrative Biology FranceAVAILABLE ON DEMAND AFTER LIVE STREAM16 05 16 20Dissecting translation start site selection in the transcription factor CEBPA with CRISPRi Samantha Fernandez University of California Berkeley USAAVAILABLE ON DEMAND AFTER LIVE STREAM16 20 16 25Transition technical setup and switch to the next session 16 25 16 35Break16 35 16 50Translation of small open reading frames in 3 UTRs enhances translation of their canonical open reading frames Qiushuang Wu Stowers Institute for Medical Research USAAVAILABLE ON DEMAND AFTER LIVE STREAM16 50 17 05Single molecule and structural analyses of human translation initiation Christopher Lapointe Stanford University School of Medicine USAAVAILABLE ON DEMAND AFTER LIVE STREAM17 05 17 35Meet the speakers of Session 4 Sunnie R Thompson Se n O Leary Urmila Sehrawat Tobias Schmidt Yuichi Shichino Bruno Klaholz Samantha Fernandez Qiushuang Wu Christopher Lapointe17 35 18 05Social break with networking opportunity18 05 18 35Roundtable Discussion with pre recorded talk presenters moderated by session chair Dasmanthie De Silva University of California Berkeley USABen Hawley Weill Cornell Medical College USAIvaylo Ivanov National Institutes of Health USAAakshi Puri McGill University CanadaShilpa Rao University of Texas USAAVAILABLE ON DEMAND AFTER LIVE STREAM18 35 19 15Social Program Virtual speed networking Rotating through 5 min meet upsin random groups of 2 3 people in a breakout room 19 15 20 30Virtual Poster Session 2Topics Interconnections and Turnover Metabolism and Disease Methods and Systems Approaches meet the poster presenters live chats and video calls 20 30 20 40Break20 40 21 55Virtual Poster Session 3Topics Ribosome Elongation Termination meet the poster presenters live chats and video calls 21 55End of day 3 Digital posters recordings and discussion channels will be available for registered participants throughout the whole virtual conference as well as 1 week before and 2 weeks after Day 4 Friday 10 September 2021 TimeSpeakerVirtual Session 5 Methods and Systems Approaches Session Chair David Gatfield University of Lausanne Switzerland14 00 14 10Introduction by Session Chair14 10 14 35Upstream and downstream of ribosomal collisions David Gatfield University of Lausanne SwitzerlandAVAILABLE ON DEMAND AFTER LIVE STREAM14 35 14 50Manipulation of global translation rates by CRISPR based targeting of rRNA transcriptionStefan Stricker Ludwig Maximilians University of Munich Helmholtz Zentrum M nchen Germany14 50 15 05A robust in vitro translation system from human cells based on dual centrifugationEvangelos Karousis University of Bern SwitzerlandAVAILABLE ON DEMAND AFTER LIVE STREAM15 05 15 10Transition technical setup and switch to the next session 15 10 15 20Break15 20 15 35Luciferase based reporter system for in vitro evaluation of elongation rate and processivity of ribosomesTiina Tamm University of Tartu EstoniaAVAILABLE ON DEMAND AFTER LIVE STREAM15 35 15 50A global and dynamic picture of rna and protein subcellular localisation in response to er stressMariavittoria Pizzinga University of Cambridge UKAVAILABLE ON DEMAND AFTER LIVE STREAM15 50 16 05Spatial discordances between mRNAs and proteins in the intestinal epitheliumYotam Harnik Weizmann Institute of Science IsraelAVAILABLE ON DEMAND AFTER LIVE STREAM16 05 16 20Regulated protein cleavage produces specialized ribosomes during erythroid differentiation to fulfil stage specific needsHuili Guo Institute of Molecular and Cell Biology SingaporeAVAILABLE ON DEMAND AFTER LIVE STREAM16 20 16 25Transition technical setup and switch to the next session 16 25 16 35Break16 35 17 00Meet the speakers of Session 5 David Gatfield Stefan Stricker Evangelos Karousis Tiina Tamm Mariavittoria Pizzinga Yotam Harnik Huili Guo17 00 17 05Break17 05 17 35Roundtable Discussion with pre recorded talk presenters moderated by session chair Paige Diamond University of California Berkeley USAMichay Diez Stowers Institute for Medical Research USAAndrew Hsieh Fred Hutchinson Cancer Research Center USADuygu Kuzuoglu Ozturk University of California USALorenzo Lafranchi Karolinska Institutet SwedenAVAILABLE ON DEMAND AFTER LIVE STREAM17 35 18 05Social break with networking opportunityVirtual Session 6 Ribosome Elongation TerminationSession Chair Jody Puglisi Stanford University Schoolof Medicine USA18 05 18 15Introduction by Session Chair18 15 18 40Dynamics of translation initiationJody Puglisi Stanford University School of Medicine USA18 40 18 55Structural basis of early translocation events on the ribosome Emily Rundlet St Jude Children s Hospital USAAVAILABLE ON DEMAND AFTER LIVE STREAM18 55 19 10Time resolved cryo EM visualizes ribosomal translocation with EF G and GTP Christine Carbone UMass Medical School USAAVAILABLE ON DEMAND AFTER LIVE STREAM19 10 19 15Transition technical setup and switch to the next session 19 15 19 25Break19 25 19 40Structural mechanism of GTPase powered ribosome tRNA movement Niels Fischer Max Planck Institute for Biophysical Chemistry GermanyAVAILABLE ON DEMAND AFTER LIVE STREAM19 40 19 55Ribosome collisions in bacteria promote ribosome rescue by triggering mRNA cleavage by SmrBHanna Kratzat Gene Center and Department of Biochemistry University of Munich Germany Kazuki Saito Johns Hopkins University School of Medicine USAAVAILABLE ON DEMAND AFTER LIVE STREAM19 55 20 10Structural basis for PoxtA mediated resistance to Phenicol and Oxazolidinone antibiotics Caillan Crowe McAuliffe University of Hamburg GermanyAVAILABLE ON DEMAND AFTER LIVE STREAM20 10 20 25Interactions with the ribosome rather than high thermodynamic stability enable regulatory mRNA stem loops to pause translation Chen Bao School of Medicine and Dentistry University of Rochester USAAVAILABLE ON DEMAND AFTER LIVE STREAM20 25 20 30Transition technical setup and switch to the next session 20 30 20 40Break20 40 20 55 Regulation of translation by dynamic site specific ribosomal RNA 2 O methylation Martin Jansson University of Copenhagen DenmarkAVAILABLE ON DEMAND AFTER LIVE STREAM20 55 21 10Investigating the dynamics of translation readthrough in live cells Kelsey Bettridge The National Institute of Diabetes and Digestive and Kidney Diseases USAAVAILABLE ON DEMAND AFTER LIVE STREAM21 10 21 40Meet the speakers of Session 6 Jody Puglisi Emily Rundlet Christine Carbone Niels Fischer Hanna Kratzat Kazuki Saito Caillan Crowe McAuliffe Chen Bao Martin Jansson Kelsey Bettridge21 40 21 50Break21 50 22 20Roundtable Discussion with pre recorded talk presenters moderated by session chair Claudia Fusco Max Planck Institute for Brain Research GermanySandeep Eswarappa Indian Institute of Science IndiaKathrin Leppek Stanford University USAEvan Mercier Max Planck Institute for Biophysical Chemistry GermanyMaxim Svetlov University of Illinois at Chicago USAAVAILABLE ON DEMAND AFTER LIVE STREAM22 20 22 30Closing remarks by F tima GebauerAVAILABLE ON DEMAND AFTER LIVE STREAM22 30End of conference Digital posters recordings and discussion channels will be available for registered participants throughout the whole virtual conference as well as 1 week before and 2 weeks after Practical information Registration Fees and Abstract Submission Registration Fees include access to all of the talks digital poster sessions and online group discussions and help us cover our costs to run the event For further information please refer to the FAQ page Academia190 EuroPhD Student140 EuroIndustry240 EuroEMBL StaffIntranet access Accredited journalists may be eligible to register for a complimentary registration Registrants may be required to provide accreditation or equivalent proof of press membership after registration Please contact Raili Pall for more information Confirmation and Payment Registration will be on a first come first served basis Your place can only be confirmed after payment of the registration fee Types of payments accepted are international bank transfers and credit card payments Abstract submission Only registered participants are eligible to submit an abstract We only accept online abstract submissions After you have logged in and successfully registered you will receive an email asking you to submit your abstract Click on the link provided and enter your abstract in the text box provided Alternatively you can submit your abstract by clicking on the link on the confirmation page directly after registering When submitting your abstract you can also apply for an oral or poster presentation A selection process will take place with the results announced 5 6 weeks after the abstract submission deadline Financial Assistance Financial Fee Waivers All academic and student registrants are invited to apply for a registration fee waiver provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO The registration fee waiver covers the registration sum that you have paid to attend the meeting Conference participants are not required to pre pay the registration fee to be selected for a fee waiver for a virtual meeting If you have already paid the registration fee and are awarded a fee waiver it will be reimbursed after the meeting Childcare Grants For participants and speakers with childcare responsibilities there is the possibility to apply for a grant provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO to offset childcare costs incurred when participating at a virtual event Eligible costs include fees for a babysitter or childcare facility or travel costs for a care giver Please note that priority will be given to early stage researchers Costs will be reimbursed after the meeting only once a reimbursement form and original receipts have been received Attendance at the event is required in order to be eligible to receive the reimbursement In order to apply for this grant you must be registered by the abstract submission deadline Application Applications for financial assistance can be submitted via the submission portal for the submission of abstracts for conferences by completing the Financial Assistance Application Section underneath the section for entering abstract motivation letter information The link to the portal can be found in the registration confirmation email that you will receive after registering for the conference For conferences if you are not submitting an abstract you can still apply for financial assistance in the submission portal Take a look at the instructions for applying for financial assistance Note that priority will be given to those submitting an abstract to present at the conference In your application you will be asked to answer questions regarding your motivation for applying and for registration fee waivers the reasons why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Selection The scientific organisers will select the recipients of registration fee waivers during the abstract selection process for conferences and the participant selection process for courses Results will be announced approximately 3 4 weeks before the event start date Selection results do not impact your admission to the meeting Registration fee waiver selection is based on your current work or study location your motivation for applying the reasons for needing financial support and the impact this event will have on your career Childcare grants are allocated based on career stage with priority given to early stage researchers Further details Check our list of external funding opportunities and read our information on attending a conference as an event reporter For further information about financial assistance please refer to the FAQ page Virtual Participation Guidelines Please do Use the event specific hashtag as communicated during the event for any related tweetsTweet unless the speaker specifically says otherwiseBe mindful of unpublished dataBe respectful in tone and content Please don t Share the link to the conference platform with anyone elseBroadcast the conference to unregistered participantsCapture transmit or redistribute data presented at the meeting unless presenter gives explicit consentUse offensive language in your postsEngage in rudeness or personal attacks Additional information can be found in our Code of Conduct Health and well being It is important to stay healthy and move around especially when you are attending an event virtually We have put together a few coffee break stretches and yoga videos You can find these under resources on the conference platform How to ask questions Please use the Q A function It is possible to send a direct message to participants poster presenters and speakers within the conference platform If you have any other questions you can go to the Help Desk on the conference platform Click on more on the top menu and click Help Desk Time zone The programme is planned based on Central European Summer Time CEST unless otherwise stated As many virtual participants are attending from around the world we do our best to accommodate as many time zones as possible when creating the programme Please take your time zone into consideration when planning your attendance Remember to set your time zone in your account Virtual event platforms We are using a virtual event platform for this conference More information about the platform will be shared ahead of the conference Sponsors Media Partners EMBO Journal an EMBO Press journal International Union of Biochemistry and Molecular Biology Open Biology a Royal Society journal RSC Chemical Biology Royal Society of Chemistry Sponsorship Opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage Request a Sponsorship Brochure Warning EMBL wishes to warn sponsors of EMBL conferences and courses of fraudulent schemes purporting to offer sponsorship opportunities on behalf of EMBL or affiliated with EMBL officials One current scam campaign of which we are aware is conducted using the name Judy Eastman judy gopcontact a2hosted com and entails approaches to sponsors offering sponsorship opportunities on EMBL s behalf Please be kindly advised that all relevant communication regarding sponsorship of EMBL conferences symposia and courses is handled by EMBL directly and is sent from an official EMBL account EMBL does not work with any external providers on sponsorship acquisition Please also note that EMBL never provides attendee lists for purchase Any offers of such are fraudulent EMBL will never call or email you to ask for your credit card details or to request a payment All payments are on invoice Suspicious communications purportedly from for or on behalf of EMBL should be reported to EMBL at the following email address sponsoring embl de...

Fátima Gebauer, Matthias W. Hentze, Jerry Pelletier, Christian Spahn

EMBL Conference

Virtual

7 September - 9 September 2021

Edit

Edit

May 05, 2021 15:302021WebinarVirtual

Description The goal of the BioStudies database is to facilitate transparency and reproducibility of research by aggregating all the outputs of a study a data package in a single place A data package may include links to parts of data deposited into specialised community databases at EMBL EBI and elsewhere as well as data that have no other natural home such as supplemental data In this webinar we will look at a range of examples for data submission and access including large image datasets...

Ugis Sarkans

Virtual

4 May - 7 May 2021

The Identity and Evolution of Cell Types

Edit

Edit

March 30, 2021 23:002021CourseVirtual

Description...

Virtual

28 March - 29 March 2021

Edit

March 23, 2021 23:002021ConferenceVirtual

Description...

Virtual

23 March - 25 March 2021

Ensembl API virtual workshop, 23rd-25th March 2021

Edit

March 23, 2021 09:002021CourseOther

Description The Ensembl project provides a comprehensive and integrated source of annotation of mainly vertebrate genome sequences This workshop is aimed at researchers and developers interested in exploring Ensembl beyond the website The workshop covers how to use the Ensembl REST APIs including understanding the major endpoints and how to write Python Perl R scripts to call them Feedback from previous courses Wish I had taken the course long time ago Didn t know before how good and powerful APIs are API workshop EMBL EBI January 2016 I really enjoyed the course and the ENSEMBL API will become a very relevant part of my toolset API workshop Cambridge December 2013 If you think you d like to host a similar course at your institute you can find out more on the Ensembl workshops page...

Other

22 March - 26 March 2021

Edit

March 16, 2021 23:002021ConferenceVirtual

Description OverviewSpeakersProgrammePractical InformationSponsors Overview EMBO and EMBL are committed to sharing research advances and sustaining scientific interaction throughout the coronavirus pandemic We are delighted to announce that the symposium is going virtual and invite you to join us online The virtual symposium includes talks from invited speakers short talk presenters digital poster sessions and networking opportunities Information about accessing the conference platform containing the live stream access to the discussion forum and digital posters will be sent to registered participants on Monday 15 March Symposium Overview Morphogenesis the generation of shape is a topic of considerable interest in basic research with important implications in biomedicine Across scales from subcellular structures to multicellular systems shape is intimately linked with function While traditional genetic approaches have allowed the identification of key components controlling individual morphogenetic processes recent advances in synthetic biology are opening the possibility to engineer gene circuits signal systems and biomaterials to not only probe morphogenesis but also to re construct it and direct it Synthetic morphogenesis is a novel and exciting field that requires collaboration among traditionally distinct scientific communities from developmental biologists to chemists theoreticians and computational modellers This symposium will bring together scientists from these different disciplines to discuss the extent to which cells tissues organs can be built de novo starting from isolated components Session Topics Origin and evolution of lifeEngineering lifeArtificial cells tissuesDevelopmental mechanismsPatterning and self organisationPhysics of life Speakers James Briscoe The Francis Crick Institute UK Jan Brugu s Max Planck Institute of Molecular Cell Biology and Genetics Germany Denis Duboule Swiss Federal Institute of Technology Lausanne Switzerland Douglas Erwin Smithsonian Institution USA Alain Goriely University of Oxford UK Edouard Hannezo Institute of Science and Technology Austria Austria Wilhelm Huck Radboud University The Netherlands Frank J licher Max Planck Institute for the Physics of Complex Systems Germany Ahmad Mo Khalil Boston University USA Mustafa Khammash ETH Z rich Switzerland Wendell Lim University of California San Francisco USA Marie Manceau Coll ge de France France Isabelle Peter California Institute of Technology USA Yolanda Schaerli University of Lausanne Switzerland Petra Schwille Max Planck Institute of Biochemistry Germany Eric Siggia The Rockefeller University USA Francesca Spagnoli King s College London UK Michael Stumpf University of Melbourne Australia Magdalena Zernicka Goetz University of Cambridge UK Scientific Organisers Justin Crocker EMBL Heidelberg Germany Stefano De Renzis EMBL Heidelberg Germany Dagmar Iber ETH Z rich Switzerland Dora Tang Max Planck Institute of Molecular Cell Biology and Genetics Germany Vikas Trivedi EMBL Barcelona Spain Conference Officers Lisa Trinh EMBL Heidelberg Germany Diah Yulianti EMBL Heidelberg Germany Programme Final Programme Got something to say Tweet it EESmorphoG The virtual conference includes live streamed invited speakers and short talk presenters with Q A sessions after each talk Information about accessing the conference platform containing the live stream access to the discussion forum and digital posters will be sent to registered participants on Monday 15 March Access to the recorded talks will be available for 2 weeks after the end of the event The following time is used in the programme below Central European Time CET eg Berlin Amsterdam Paris To find out the equivalent time zone in your location enter Berlin the CET programme time and your city into the Time Zone Converter Day 1 Wednesday 17 March 2021 TimeSpeaker12 45 13 00 CET Opening remarks13 00 13 10 CET Meet the editors13 10 15 25 CET Session 1 Origin and evolution of lifeChairs Justin Crocker and Vikas Trivedi13 10 13 35 CET Evolutionary dynamics of the regulatory genome and expanding developmental opportunitiesDouglas Erwin Smithsonian Institution USA13 35 13 40 CET Transition setup and switch to the next live talk 13 40 13 55 CET Compositional identity and robustness of compartmentalized self reproducing catalytic RNAsSandeep Ameta National Center for Biological Sciences India13 55 14 00 CET Transition setup and switch to the next live talk 14 00 14 25 CET Shape dynamics and division of active droplets and active vesiclesFrank J licher Max Planck Institute for the Physics of Complex Systems Germany14 25 14 40 CET Short break14 40 14 55 CET Reconstitution of ancient innovation transforms tissue architecture and sealingViola Noeske Heidelberg University Germany14 55 15 00 CET Transition setup and switch to the next live talk 15 00 15 25 CET Conservation and evolutionary flexibility in developmental gene regulatory networksIsabelle Peter California Institute of Technology USA15 25 15 30 CET Transition switch to individual Zoom rooms 15 30 16 00 CET Meet the speakers session 1 in individual Zoom rooms with Doug Erwin Frank J licher and Isabelle Peter16 00 17 30 CET Break and digital poster session 117 30 20 15 CET Session 2 Engineering lifeChairs Dora Tang and Stefano De Renzis17 30 17 55 CET Cell dynamics of self organising feather pattern fidelityMarie Manceau Coll ge de France France17 55 18 00 CET Transition setup and switch to the next live talk 18 00 18 15 CET Programming mechano chemical coupling between a reaction diffusion system and active matterAnis Senoussi Sorbonne University and CNRS France18 15 18 20 CET Transition setup and switch to the next live talk 18 20 18 45 CET Bottom up design of protein self organizationPetra Schwille Max Planck Institute of Biochemistry Germany18 45 19 00 CET Short break19 00 19 25 CET Physical biology of synthetic cellsWilhelm Huck Radboud University The Netherlands19 25 19 30 CET Transition setup and switch to the next live talk 19 30 19 45 CET Integrated computational and in vitro systems for design and characterization of established and novel synthetic development systemsLeonardo Morsut University of Southern California USA19 45 19 50 CET Transition setup and switch to the next live talk 19 50 20 15 CET Programming self organizing tissuesWendell Lim University of California San Francisco USA20 15 20 20 CET Transition switch to individual Zoom rooms 20 20 20 50 CET Meet the speakers session 2 in individual Zoom rooms with Marie Manceau Petra Schwille Wilhelm Huck and Wendell Lim20 50 21 00 CET Short break21 00 22 00 CET Social programme online speed networking22 00 CET End of day 1 Continued access to digital posters networking and discussion platforms Day 2 Thursday 18 March 2021 TimeSpeaker14 00 16 35 CET Session 3 Artificial cells tissuesChairs Vikas Trivedi and Justin Crocker14 00 14 25 CET Synthetic gene regulatory networks for spatiotemporal pattern formation in populations of E coli cellsYolanda Schaerli University of Lausanne Switzerland14 25 14 30 CET Transition setup and switch to the next live talk 14 30 14 45 CET Self organized perfusable capillary network in vitro Experiment and modelingTakashi Miura Kyushu University Japan14 45 14 50 CET Transition setup and switch to the next live talk 14 50 15 15 CET Cooperativity and the design of gene regulatory circuitsAhmad Mo Khalil Boston University USA15 15 15 30 CET Short break15 30 15 45 CET Self organized morphogenesis of an in vitro human neural tubeEyal Karzbrun University of California Santa Barbara USA15 45 15 50 CET Transition setup and switch to the next live talk 15 50 16 15 CET Optogenetic gene networks recapitulate dynamic cellular signal processingMustafa Khammash ETH Zurich Switzerland16 15 16 20 CET Transition switch to individual Zoom rooms 16 20 16 50 CET Meet the speakers session 3 in individual Zoom rooms with Yolanda Schaerli Ahmad S Khalil and Mustafa Khammash16 50 18 20 CET Break and digital poster session 218 20 20 35 CET Session 4 Developmental mechanismsChairs Vikas Trivedi and Stefano De Renzis18 20 18 45 CET Engineering pancreatic tissue Cells in time and spaceFrancesca M Spagnoli King s College London UK18 45 18 50 CET Transition setup and switch to the next live talk 18 50 19 05 CET Ex utero development of mouse embryos from pre gastrulation to advanced organogenesis Alejandro Aguilera Castrejon Weizmann Institute of Science Israel19 05 19 10 CET Transition setup and switch to the next live talk 19 10 19 35 CET Talk title to be announcedMagdalena Zernicka Goetz University of Cambridge UK19 35 19 50 CET Short break19 50 20 05 CET Tackling the mesoscale of gastrulation movements Developmental downregulation of cell cortex contractility accounts for the plasticity of migrating mesodermFrancois Fagotto CRBM University of Montpellier and CNRS France McGill University Canada20 05 20 10 CET Transition setup and switch to the next live talk 20 10 20 35 CET Design principles in pattern formation Robustness and equivalencesMichael Stumpf University of Melbourne Australia20 35 20 40 CET Transition switch to individual Zoom rooms 20 40 21 10 CET Meet the speakers session 4 in individual Zoom rooms with Francesca M Spagnoli Magdalena Zernicka Goetz and Michael Stumpf21 10 21 20 CET Short break21 20 22 20 CET Social programme virtual bar mixer open with Live Music by Lazy Fur22 20 CET End of day 2 Continued access to digital posters networking and discussion platforms Day 3 Friday 19 March 2021 TimeSpeaker12 45 13 00 CET Horizon Europe European Innovation Council EIC PathfinderBarbara Gerratana European Innovation Council Pilot Research Executive Agency13 00 15 15 CET Session 5 Patterning and self organizationChairs Stefano De Renzis and Dagmar Iber13 00 13 25 CET The cellular and molecular logic of spinal cord developmentJames Briscoe The Francis Crick Institute UK13 25 13 30 CET Transition setup and switch to the next live talk 13 30 13 45 CET Schemes for programmable pattern formation in compartmentalised systems with local signallingUlrich Gerland Technical University of Munich Germany13 45 13 50 CET Transition setup and switch to the next live talk 13 50 14 15 CET Artificial embryos to study long range gene regulationDenis Duboule Swiss Federal Institute of Technology Lausanne Switzerland14 15 14 30 CET Short break14 30 14 45 CET Patterning and growth control in vivo by an engineered GFP gradientKristina S Stapornwongkul The Francis Crick Institute UK14 45 14 50 CET Transition setup and switch to the next live talk 14 50 15 15 CET Self assembly of multi lineage human stem cell systemsEric D Siggia The Rockefeller University USA15 15 15 20 CET Transition switch to individual Zoom rooms 15 20 15 50 CET Meet the speakers session 5 in individual Zoom rooms with James Briscoe Denis Duboule and Eric D Siggia15 50 17 20 CET Break and digital poster session 317 20 20 15 CET Session 6 Physics of lifeChairs Dagmar Iber and Dora Tang17 20 17 45 CET Talk title to be announcedJan Brugu s Max Planck Institute of Molecular Cell Biology and Genetics Germany17 45 17 50 CET Transition setup and switch to the next live talk 17 50 18 05 CET Understanding the tubologenesis of bile canaliculi one cell at a timeVirgile Viasnoff National University of Singapore Singapore18 05 18 10 CET Transition setup and switch to the next live talk 18 10 18 25 CET Arrested coalescence of multicellular aggregatesDavid Oriola EMBL Barcelona Spain18 25 18 30 CET Transition setup and switch to the next live talk 18 30 18 55 CET Rigidity percolation as a structural basis of embryonic tissue phase transitionsEdouard Hannezo Institute of Science and Technology Austria Austria18 55 19 10 CET Short break19 10 19 25 CET Somite surface tension buffers imprecise segment lengths to ensure increased precision and left right symmetrySundar R Naganathan Swiss Federal Institute of Technology Lausanne Switzerland19 25 19 30 CET Transition setup and switch to the next live talk 19 30 19 45 CET Engineering epithelial shape and mechanics from the bottom upAriadna Mar n Llaurad Institute for Bioengineering of Catalonia Spain19 45 19 50 CET Transition setup and switch to the next live talk 19 50 20 15 CET A field theory of axonal growth and guidanceAlain Goriely University of Oxford UK20 15 20 25 CET Closing remarks20 25 20 30 CET Transition switch to individual Zoom rooms 20 30 21 00 CET Meet the speakers session 6 in individual Zoom rooms with Jan Brugu s Edouard Hannezo and Alain Goriely21 00 CET End of conference Continued access to digital posters networking and discussion platforms for 2 weeks after the conference Practical Information Registration Fees and Abstract Submission Registration for this event is now closed Registration Fees include access to all of the talks online group discussions and help us cover our costs to run the event Academia190 EuroPhD Student140 EuroIndustry240 EuroEMBL StaffIntranet access Accredited journalists may be eligible to register for a reduced press rate or in some cases for complimentary registration Registrants may be required to provide accreditation or equivalent proof of press membership after registration Please contact Lisa Trinh for more information Confirmation and Payment Registration will be on a first come first served basis Your place can only be confirmed after payment of the registration fee Types of payments accepted are international bank transfers only up to 8 weeks before event and credit card payments Abstract submission Only registered participants are eligible to submit an abstract We only accept online abstract submissions After registration you can submit your abstract via a separate link that will be provided in the email confirmation Alternatively you can access the link on the confirmation page directly after registering The same login credentials are used for both processes Please note Title The title should not exceed 20 words Only the first word of the title should start with a capital letter and the rest of the title should be in lowercase Authors and Affiliations Please fill in the author s details as requested in the online form The compulsory details are First Name Last Name Organisation Name Affiliation or Company Country and Email Mark only one author as the role of First author and please don t forget to indicate who will be presenting The order of the authors will be listed as follows First Author Co First Author alphabetically if multiple co author s in the order added by the submitter Presentation Types When submitting your abstract you can apply for an oral or poster presentation A selection process will take place with the results announced 2 3 weeks after the abstract submission deadline Please check our FAQs pages for further information on how to submit an abstract Financial Assistance Financial Assistance Registration Fee Waivers All academic and student registrants are invited to apply for a registration fee waiver provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO The registration fee waiver covers the registration sum that you have paid to attend the meeting Conference participants are not required to pre pay the registration fee to be selected for a fee waiver for a virtual meeting If you have already paid the registration fee and are awarded a fee waiver it will be reimbursed after the meeting Course participants are required to pay the course fee in advance which will then be reimbursed after the course to the fee waiver recipients Childcare GrantsFor participants with children there is the possibility to apply for a childcare grant provided by the EMBL Advanced Training Centre Corporate Partnership Programme to offset childcare costs incurred by participants or speakers when participating at a virtual event Eligible costs include fees for a babysitter or childcare facility or travel costs for a care giver Please note that priority will be given to early stage researchers A maximum amount of 500 EUR can be awarded per participant selected for the virtual childcare grant Costs will be reimbursed after the meeting only once a reimbursement form and original receipts have been received In order to apply for this grant you must be registered by the abstract submission deadline Application Registration Fee Waivers You may apply for financial assistance when submitting your abstract for this conference In your application you will be asked to answer questions regarding your motivation for applying reasons why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Childcare Grants Participants registered by the abstract deadline will be emailed information about the childcare grants You should apply for the grant by the deadline specified in the email Selection The scientific organisers will select the recipients of registration fee waivers during the abstract selection process Results will be announced approximately 3 4 weeks before the event start date Selection results do not impact your admission to the meeting Registration fee waiver selection is based on your current work or study location your motivation for applying the reasons for needing financial support and the impact this event will have on your career Childcare grants are allocated based on career stage with priority given to early stage researchers Further details For further information about financial assistance please refer to the FAQ page Virtual Participation Guidelines Guidelines Please do Use the event specific hashtag EESmorphoG as communicated during the event for any related tweetsTweet unless the speaker specifically says otherwiseBe mindful of unpublished dataBe respectful in tone and content Please don t Share the live stream poster session or conference platform access links with othersBroadcast the conference to unregistered participantsCapture transmit or redistribute data presented at the meeting unless presenter gives explicit consentUse offensive language in your postsEngage in rudeness or personal attacks Additional information can be found in our Code of Conduct Health and well being It is important to stay healthy and move around especially when you are attending an event virtually We have put together a few coffee break stretches and yoga videos You can find these under resources on the conference platform How to ask questions Please use the Q A function It is possible to send a direct message to participants poster presenters and speakers within the conference platform If you have any other questions you can go to the Help Desk on the conference platform Click on more on the top menu and click Help Desk Time zone The programme is planned based on Central European Time CET or Central European Summer Time CEST unless otherwise stated As many virtual participants are attending from around the world we do our best to accommodate as many timezones as possible when creating the programme Please take your time zone into consideration when planning your attendance Virtual event platforms We are using a virtual event platform for this conference More information about the platform will be shared ahead of the conference Sponsors Media partners Development a The Company of Biologists journal Molecular Systems Biology an EMBO Press journal Open Biology a Royal Society journal Sponsorship Opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage...

Virtual

16 March - 18 March 2021

Virtual Ensembl Browser workshop, 16th-18th March

Edit

March 16, 2021 00:002021CourseVirtual

Description Work with the Ensembl Outreach team to get to grips with the Ensembl browser accessing gene variation comparative genomics and regulation data mine these data with BioMart and visualising your own data in Ensembl...

Michal Szpak

Virtual

16 March - 19 March 2021

Introduction to RNA-seq and functional interpretation

Edit

March 16, 2021 00:002021CourseVirtual

Description Gain an introduction to the technology data analysis tools and resources used in RNA sequencing and transcriptomics The content will provide a broad overview of the subject area and introduce participants to basic analysis of transcriptomics data using the command line It will also highlight key public data repositories and methodologies that can be used to start the biological interpretation of expression data Topics will be delivered using a mixture of lectures practical exercises and open discussions Computational work during the course will use small example data sets and there will be no opportunity to analyse personal data Virtual course Participants will learn via a mix of pre recorded lectures live presentations and trainer Q A sessions Practical experience will be developed through group activities and trainer led computational exercises Live sessions will be delivered using Zoom with additional support and communication via Slack Pre recorded material will be made available to registered participants prior to the start of the course and in the week before the course there will be a brief induction session Computational practicals will run on EMBL EBI s virtual training infrastructure meaning participants will not require access to a powerful computer or install complex software on their own machines Participants will need to be available between the hours of 09 30 17 30 GMT each day of the course Trainers will be available to assist answer questions and further explain the analysis during these times...

Meredith Wilmott

Virtual

10 March 2021

Introduction to exploring genome-phenome data with EGA

Edit

March 10, 2021 15:302021WebinarVirtual

Description European Genome phenome Archive EGA is a permanent repository for all types of potentially identifiable genetic and phenotypic data from biomedical research projects This webinar aims to cover a quick introduction to EGA by exploring topics ranging from searching and accessing data in EGA to interpreting Data Use Ontology DUO codes We will also demonstrate downloading data with an EGA test account...

Dona Shaju, Giselle Kerry

Virtual

8 March - 11 March 2021

Edit

March 02, 2021 00:002021ConferenceVirtual

Description OverviewSpeakersProgrammePractical informationSponsorsAbout Overview EMBO and EMBL are committed to sharing research advances and sustaining scientific interaction throughout the coronavirus pandemic We are delighted to announce that the symposium is going virtual and invite you to join us online The virtual symposium includes talks from invited speakers short talk presenters digital poster sessions and networking opportunities To accommodate a worldwide audience all talks will be pre recorded and made available to registered participants 10 days before the start of the conference Live discussion sessions will be held during the event and each session will be held twice allowing participants to attend the session which best fits their timezone Symposium Overview The cell surface comprising the plasma membrane the underlying cortical cytoskeleton and in many cell types a cell wall is a central integrator of cell form and function Its physico chemical properties are rapidly modulated to accommodate or drive changes in shape or behaviour and to exchange matter and information with the environment This symposium will bring together researchers from different communities interested in processes occurring at the cell surface across kingdoms It will focus on new technologies that empower studies of cell wall actin and membrane biology such as advanced imaging in in vitro and in vivo systems as well as approaches combining molecular biology with computational and biophysical approaches Speakers P l Martin Bendix University of Copenhagen Denmark Daniel A Fletcher University of California Berkeley USA Zev Gartner University of California San Francisco USA Raymond E Goldstein University of Cambridge UK Olivier Hamant cole Normale Sup rieure de Lyon France Henrik J nsson University of Cambridge UK Anne Marie Krachler The University of Texas Health Science Center at Houston USA Wanda Kukulski University of Bern Switzerland Lisa Manning Syracuse University USA Nicolas Minc Institut Jacques Monod France Anne C cile Reymann Institute of Genetics and Molecular and Cellular Biology France Aur lien Roux University of Geneva Switzerland B n dicte Sanson University of Cambridge UK An ela ari University College London UK Anna Marie Sokac University of Illinois at Urbana Champaign USA Howard Stone Princeton University USA C cile Sykes cole normale sup rieure PSL CNRS France Marcus J Taylor Max Planck Institute for Infection Biology Germany Scientific Organisers Alba Diz Munoz EMBL Heidelberg Germany Zemer Gitai Princeton University USA KC Huang Stanford University USA Ewa Paluch University of Cambridge UK Conference Officers Maria Mercedes Bacadare Goitia EMBL Heidelberg Germany Nathalie Sneider EMBL Heidelberg Germany Programme Preliminary Programme Registered participants will receive final details including information about accessing pre recorded talks and links to the online platform 1 2 weeks before the start of the conference Got something to say Tweet it with EESCellSurface To accommodate a worldwide audience all talks will be pre recorded and made available to registered participants 10 days before the start of the conference Live discussion sessions will be held during the event and each session will be held twice allowing participants to attend the session which best fits their timezone The following times are used in the programme below Central European Time CET eg Berlin Amsterdam ParisEastern Standard Time EST eg New York Quebec Pre conference All talks will be pre recorded and made available 10 days before the start of the conference Registered participants are encouraged to view these before Day 1 of the conference There will be the opportunity to ask questions during the live discussion sessions Day 1 Tuesday 2 March 2021 Time Speaker 10 00 10 10 CET 04 00 04 10 EST Opening remarks 10 10 14 30 CET 04 00 08 30 EST Morning Discussion Sessions 10 10 10 55 CET 04 10 04 55 EST Discussion Session 1 morning Shape adaptation mechanisms at the cell surface Moderator Ewa Paluch University of Cambridge UK 1A B n dicte Sanson University of Cambridge UK 1A C cile Sykes CNRS Institut Curie France 1B Anne C cile Reymann Institute of Genetics and Molecular and Cellular Biology France 1B Nicolas Minc Institut Jacques Monod France Plus 2 pre recorded short talk speakers Bas Jacobs Wageningen University Research The Netherlands Lara Selvaggi University of Zurich Switzerland 10 55 11 00 CET 04 55 05 00 EST Break 11 00 11 45 CET 05 00 05 45 EST Discussion Session 2 morning High resolution mechanics of membrane shaping proteins Chair Alba Diz Munoz EMBL Heidelberg Germany 2A Andela ari University College London UK 2A P l Martin Bendix University of Copenhagen Denmark 2B Wanda Kukulski University of Bern Switzerland 2B Aur lien Roux University of Geneva Switzerland Plus 2 selected short talk speakers Anabel Lise Le Roux Institute for Bioengineering of Catalonia Spain Wenting Zhao Nanyang Technological Unviersity Singapore 11 45 12 00 CET 05 45 06 00 EST Break 12 00 13 00 CET 06 00 07 00 EST Virtual Poster Session 1 13 00 13 30 CET 07 00 07 30 EST Career Development Session morning Moderator Alba Diz Munoz EMBL Heidelberg Germany Panelists Alba Diz Munoz EMBL Heidelberg Germany Henrik J nsson University of Cambridge UK Ewa Paluch University of Cambridge UK Andela ari University College London UK 13 30 14 00 CET 07 30 08 00 EST Optional Virtual Coffee Break 14 00 14 30 CET 08 00 08 30 EST Discussion Session 3 morning From nanometer scale organization to micron scale function Cell cell signaling and spindle assembly Chair Alba Diz Munoz EMBL Heidelberg Germany Howard Stone Princeton University USA Daniel A Fletcher University of California Berkeley USA Plus 1 selected short talk speaker Veneta Gerganova University of Lausanne Switzerland 14 30 15 00 CET 08 30 09 00 EST Break 15 00 17 30 CET 09 00 11 30 EST Afternoon Discussion Sessions 15 00 15 45 CET 09 00 09 45 EST Discussion Session 1 afternoon Shape adaptation mechanisms at the cell surface Chair KC Huang Stanford University USA 1A B n dicte Sanson University of Cambridge UK 1A C cile Sykes CNRS Institut Curie France 1B Anne C cile Reymann Institute of Genetics and Molecular and Cellular Biology France 1B Nicolas Minc Institut Jacques Monod France Plus 2 selected short talk speakers Sergio Lembo EMBL Heidelberg Germany Sven van Teeffelen University of Montreal Canada 15 45 16 00 CET 09 45 10 00 EST Break 16 00 16 45 CET 10 00 10 45 EST Discussion Session 2 afternoon High resolution mechanics of membrane shaping proteins Chair Zemer Gitai Princeton University USA 2A Andela ari University College London UK 2A P l Martin Bendix University of Copenhagen Denmark 2B Wanda Kukulski University of Bern Switzerland 2B Aur lien Roux University of Geneva Switzerland Plus 2 selected short talk speakers Ankita Jha National Institutes of Health USA James Saenz B CUBE Center for Molecular Bioengineering TU Dresden Germany 16 45 17 00 CET 10 45 11 00 EST Break 17 00 17 30 CET 11 00 11 30 EST Discussion Session 3 afternoon From nanometer scale organization to micron scale function Cell cell signaling and spindle assembly Chair Zemer Gitai Princeton University USA Howard Stone Princeton University USA Daniel A Fletcher University of California Berkeley USA Plus 1 selected short talk speaker Xavier Pierrat cole Polytechnique F d rale de Lausanne Switzerland 17 30 17 45 CET 11 30 11 45 EDT Break 17 45 18 15 CET 11 45 12 15 EST Career Development Session afternoon Moderator Zemer Gitai Princeton University USA Panelists Zemer Gitai Princeton University USA KC Huang Stanford University USA Henrik J nsson University of Cambridge UK Anna Marie Sokac University of Illinois at Urbana Champaign USA 18 15 19 15 CET 12 15 13 15 EST Virtual Poster Session 2 19 15 19 45 CET 13 15 13 45 EST Optional Virtual Speed Networking 19 45 CET 13 45 EST End of Day 1 continued access to digital posters pre recorded talks and virtual networking and discussions Day 2 Wednesday 3 March 2020 Time Speaker Continued access to digital posters pre recorded talks and virtual networking and discussions 10 00 10 45 CET 04 00 04 45 EST Discussion Session 4 morning Elucidating multicellular morphology and signaling using live imaging and mechanical modeling Chair Ewa Paluch University of Cambridge UK4A Henrik J nsson University of Cambridge UK 4A Anne Marie Krachler The University of Texas Health Science Center at Houston USA 4B Lisa Manning The University of Texas Health Science Center at Houston USA 4B Marcus J Taylor Max Planck Institute for Infection Biology Germany Plus 2 selected short talk speakers Timothy Saunders National University of Singapore Singapore Guilherme Ventura University of Copenhagen Denmark 10 45 11 00 CET 04 45 05 00 EST Break 11 00 11 45 CET 05 00 05 45 EST Discussion Session 5 morning Finding the underlying principles of cell surface mechanics through inter kingdom comparisons Chair Alba Diz Munoz EMBL Heidelberg Germany5A Anna Marie Sokac University of Illinois at Urbana Champaign USA 5A Olivier Hamant cole Normale Sup rieure de Lyon France 5B Raymond E Goldstein University of Cambridge UK 5B Zev Gartner University of California San Francisco USA Plus 2 selected short talk speakers Nicolas Jolivert INRS Institut Armand Frappier Canada Chlo Roffay University of Geneva Switzerland 11 45 12 00 CET 05 45 06 00 EST Break 12 00 12 30 CET 06 00 06 30 EST Meet the Editor Moderator Alba Diz Munoz EMBL Heidelberg Germany Ines Alvarez Garcia PLoS Bio Abi Klopper Nature Physics Dominique Morneau Nature Reviews Martina Rembold EMBO 12 30 13 00 CET 06 30 07 00 EST Optional Virtual Coffee Break 13 00 14 00 CET 07 00 08 00 EST Break 14 00 15 00 CET 08 00 09 00 EST Virtual Poster Session 3 15 00 15 45 CET 09 00 09 45 EST Discussion Session 4 afternoon Elucidating multicellular morphology and signaling using live imaging and mechanical modeling Chair KC Huang Stanford University USA4A Henrik J nsson University of Cambridge UK 4A Anne Marie Krachler The University of Texas Health Science Center at Houston USA 4B Lisa Manning The University of Texas Health Science Center at Houston USA 4B Marcus J Taylor Max Planck Institute for Infection Biology Germany Plus 2 selected short talk speakers Effie Bastounis University of Washington USA Gerardo Ceada Institute for Bioengineering of Catalonia Spain 15 45 16 00 CET 09 45 10 00 EST Break 16 00 16 45 CET 10 00 10 45 EST Discussion Session 5 afternoon Finding the underlying principles of cell surface mechanics through inter kingdom comparisons Chair Zemer Gitai Princeton University USA5A Anna Marie Sokac University of Illinois at Urbana Champaign USA 5A Olivier Hamant cole Normale Sup rieure de Lyon France 5B Raymond E Goldstein University of Cambridge UK 5B Zev Gartner University of California San Francisco USA Plus 2 selected short talk speakers Benjamin Bratton Princeton University USA Shiladtitya Banerjee Carnegie Mellon University USA 16 45 17 00 CET 10 45 11 00 EST Break 17 00 17 30 CET 11 00 11 30 EST Meet the Editor Moderator Alba Diz Munoz EMBL Heidelberg Germany Ines Alvarez Garcia PLoS Bio Stella Hurtley Abi Klopper Nature Physics 17 30 18 30 CET 11 30 12 30 EST Virtual Bar Mixer with live jazz all speakers and participants are invited to join The link will be shared in the conference platform Enjoy a drink and chat with other conference participants in randomly assigned Zoom breakout rooms Live jazz will start and finish the session 18 30 18 40 CET 12 30 12 40 EST Closing 18 40 CET 12 40 EST End of conference access to digital posters pre recorded talks and virtual networking and discussions will continue to be available for 14 days Practical information Registration Fees and Abstract Submission To accommodate a worldwide audience all talks will be pre recorded and made available to registered participants 10 days before the start of the conference Live discussion sessions will be held during the event and each session will be held twice allowing participants to attend the session which best fits their timezone Registration Fees include access to all of the talks online group discussions and help us cover our costs to run the event Academia190 EuroPhD Student140 EuroIndustry240 EuroEMBL StaffIntranet access Accredited journalists may be eligible to register for a reduced press rate or in some cases for complimentary registration Registrants may be required to provide accreditation or equivalent proof of press membership after registration Please contact Nathalie Sneider for more information Confirmation and Payment Registration will be on a first come first served basis Your place can only be confirmed after payment of the registration fee Types of payments accepted are international bank transfers only up to 8 weeks before event and credit card payments Abstract submission Only registered participants are eligible to submit an abstract We only accept online abstract submissions After registration you can submit your abstract via a separate link that will be provided in the email confirmation Alternatively you can access the link on the confirmation page directly after registering The same login credentials are used for both processes Please note Title The title should not exceed 20 words Only the first word of the title should start with a capital letter and the rest of the title should be in lowercase Authors and Affiliations Please fill in the author s details as requested in the online form The compulsory details are First Name Last Name Organisation Name Affiliation or Company Country and Email Mark only one author as the role of First author and please don t forget to indicate who will be presenting The order of the authors will be listed as follows First Author Co First Author alphabetically if multiple co author s in the order added by the submitter Presentation Types When submitting your abstract you can apply for an oral or poster presentation A selection process will take place with the results announced 2 3 weeks after the abstract submission deadline Please check our FAQs pages for further information on how to submit an abstract Financial Assistance Financial Assistance Registration Fee Waivers All academic and student registrants are invited to apply for a registration fee waiver provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO The registration fee waiver covers the registration sum that you have paid to attend the meeting Conference participants are not required to pre pay the registration fee to be selected for a fee waiver for a virtual meeting If you have already paid the registration fee and are awarded a fee waiver it will be reimbursed after the meeting Course participants are required to pay the course fee in advance which will then be reimbursed after the course to the fee waiver recipients Childcare GrantsFor participants with children there is the possibility to apply for a childcare grant provided by the EMBL Advanced Training Centre Corporate Partnership Programme to offset childcare costs incurred by participants or speakers when participating at a virtual event Eligible costs include fees for a babysitter or childcare facility or travel costs for a care giver Please note that priority will be given to early stage researchers A maximum amount of 500 EUR can be awarded per participant selected for the virtual childcare grant Costs will be reimbursed after the meeting only once a reimbursement form and original receipts have been received In order to apply for this grant you must be registered by the abstract submission deadline Application Registration Fee Waivers You may apply for financial assistance when submitting your abstract for this conference In your application you will be asked to answer questions regarding your motivation for applying reasons why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application Childcare Grants Participants registered by the abstract deadline will be emailed information about the childcare grants You should apply for the grant by the deadline specified in the email Selection The scientific organisers will select the recipients of registration fee waivers during the abstract selection process Results will be announced approximately 3 4 weeks before the event start date Selection results do not impact your admission to the meeting Registration fee waiver selection is based on your current work or study location your motivation for applying the reasons for needing financial support and the impact this event will have on your career Childcare grants are allocated based on career stage with priority given to early stage researchers Further details For further information about financial assistance please refer to the FAQ page Virtual Participation Guidelines Guidelines Please do Use the event specific hashtag as communicated during the event for any related tweetsTweet unless the speaker specifically says otherwiseBe mindful of unpublished dataBe respectful in tone and content Please don t Share Slack live stream or poster session links with othersBroadcast the conference to unregistered participantsCapture transmit or redistribute data presented at the meeting unless presenter gives explicit consentUse offensive language in your postsEngage in rudeness or personal attacks Additional information can be found in our Code of Conduct Health and well being It is important to stay healthy and move around especially when you are attending an event virtually We have put together a few coffee break stretches and yoga videos in the events Slack workspace for you to enjoy during the event How to ask questions Questions during and after the talks can be asked in live streaming platform The chair moderates the questions and shares them with the speaker If time runs out or you think of a question later you can use Slack to ask your questions in the dedicated session channels or via direct message Time zone The programme is planned based on Central European Summer Time CEST unless otherwise stated As many virtual participants are attending from around the world we do our best to accomodate as many timezones as possible when creating the programme Please take your time zone into consideration when planning your attendance Virtual event platforms Slack This platform will be used to collaborate communicate and network with all of the attendees of this event All participants will receive information on how to join shortly before the conference To get the most out of Slack see our useful guide Zoom Access to all live streamed talks will be through this platform and Media Site below We suggest you download the Zoom App https zoom us download as it is more reliable and stable than the web browser Zoom will also be used be the networking aspects of the programme EMBL Media Site Recorded talks will be available on demand through Media Site A link and individualised login information will be sent shortly before the conference Recorded talks will be saved here until Saturday 5 September 2020 Please use the preferred browser Chrome iPosters virtual Poster Gallery for Poster Sessions The digital posters will be held on a web based platform from iPosterSessions The company will contact the submitter of the abstract with login information and instructions on how to create and present a digital poster The platform offers different poster layouts to choose from with the ability to upload images and videos to make your digital poster presentation more engaging There is a chat functionality within the website and there will be a poster session Q A during the session in Slack Here are some guidelines for using iPosters Sponsors Sponsorship Opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage About EMBO EMBL Symposia promote scientific communication and collaboration in the European research area They provide scientists with a platform to discuss and exchange ideas on forward looking topics and new developments in the life sciences Topics emphasise upcoming developments and the interdisciplinary nature of related fields Jointly funded and organised by EMBO and EMBL and complementary to their respective courses workshops and conference programmes the symposia promote scientific communication and collaboration All symposia are held in the EMBL Advanced Training Centre ATC in Heidelberg Germany or virtually...

Virtual

1 March - 5 March 2021

Edit

February 28, 2021 23:002021CourseEMBL Heidelberg

Description Attacking Open Chromatin with ATAC Sequencing...

EMBL Heidelberg

22 February - 26 February 2021

Introduction to multi-omics data integration and visualisation

Edit

February 22, 2021 00:002021CourseVirtual

Description Identify the challenges strategies and resources for multi omics data integration using biological examples The virtual course will focus on the use of public data resources and open access tools for enabling integrated working with an emphasis on data visualisation Working with public domain data can provide added value to data derived through a researcher s own work and additionally inform experimental design This course is highly relevant in the current research scenario where an increased volume of data across the whole spectrum of biology has created both more opportunities and challenges to identifying novel perspectives and answering questions in the life sciences This course will focus on issues around data integration but will not include systems biology modelling or machine learning approaches A major element of this course is a group project where participants will be organised in small groups to work together on a challenge set by trainers from EMBL EBI data resource and research teams These will allow participants to explore the bioinformatics tools and resources introduced in the course and to apply these to a set problem providing hands on experience of relevance to their own research The group work will culminate in a presentation session involving all participants on the final day of the course giving an opportunity for wider discussion on the benefits and challenges of integrating data Virtual course The course will involve participants learning via pre recorded lectures live presentations and trainer Q A sessions The content will be delivered over Zoom with additional text communication over Slack Computational practicals will be run on EMBL EBI s virtual training infrastructure this means there is no need to have a powerful computer to run exercises or a requirement to install complex software before the course Trainers will be available to provide support answer questions and further explain the analysis during these practicals Participants will need to be available between the hours of 09 30 17 30 GMT each day of the course...

Jane Reynolds

Virtual

16 February 2021

Ensembl API workshop, University of Cambridge, 16.02.2021

Edit

February 16, 2021 09:002021CourseOther

Other

15 February - 19 February 2021

Next generation sequencing bioinformatics

Edit

February 15, 2021 00:002021CourseVirtual

Description A guide to the technology analysis workflows tools and resources for next generation sequencing data analysis This virtual course will provide insights into how biological knowledge can be derived from genomics experiments and explain different approaches in analysing such data The main focus will be on assembly re sequencing and variant calling during the analysis of higher eukaryotes with a particular emphasis on human genetic research Throughout the week more advanced topics will introduce the creation of pipelines automation and the scaling up of analysis experiments Practical sessions will enable participants to process training datasets and apply appropriate statistical methods in their analyses There will be no opportunity to work with personal research data during the course Virtual course Participants will learn via a mix of pre recorded lectures live presentations and trainer Q A sessions Practical experience will be developed through group activities and trainer led computational exercises Live sessions will be delivered using Zoom with additional support and communication via Slack Pre recorded material will be made available to registered participants prior to the start of the course and in the week before the course there will be a brief induction session Computational practicals will run on EMBL EBI s virtual training infrastructure meaning participants will not require access to a powerful computer or install complex software on their own machines Participants will need to be available between the hours of 09 30 17 30 GMT each day of the course Trainers will be available to assist answer questions and further explain the analysis during these times...

Marina Pujol

Virtual

11 February 2021

Ensembl Browser workshop, University of Cambridge, 11.02.2021

Edit

February 11, 2021 09:002021CourseOther

Description The Ensembl project at www ensembl org provides a comprehensive and integrated source of annotation of mainly vertebrate genome sequences This 1 day workshop offers participants the possibility of gaining hands on experience in the use of the Ensembl genome browser but also provides them with the necessary background information Our sister project at www ensemblgenomes org can also be covered if participants are working with bacteria plants fungi protists or invertebrate metazoa The workshop is primarily targeted at wetlab researchers and we customise the course for species of interest and to include total beginners to our browser up through frequent users Feedback from previous courses There are probably quite few people out there who all assume that Ensembl today is the same as it was years ago It is not With many new features and datasets incorporated interlinked it offers data exploration like never before This course was a very useful update on what Ensembl has become Browser workshop CRUK April 2016 Very useful workshop certainly one of the most informative and useful I have attended Delivered by someone who was extremely familiar with the website and its capabilities not someone who had used it a couple of times and proclaimed themselves to be an expert Browser workshop Cardiff March 2014 If you think you d like to host a similar course at your institute you can find out more on the Ensembl workshops page...

Other

10 February 2021

Exploring non‐coding RNAs in RNAcentral

Edit

February 10, 2021 15:302021WebinarVirtual

Description RNAcentral is a database of non coding RNA sequences that provides a unified view of 40 specialised databases This webinar will give an overview of the data found in RNAcentral as well as the RNAcentral website The team will share tips on how to efficiently explore the data using text and sequence similarity search how to visualise RNA secondary structure and how to access the bulk data in the FTP archive More advanced functionality including the programmatic data access and public Postgres database will also be discussed Join the webinar to also learn what s new in RNAcentral or ask any questions you may have...

Blake Sweeney, Carlos Ribas, Anton Petrov

Virtual

8 February - 12 February 2021

Immune Profiling of Single Cells

Edit

February 08, 2021 08:002021CourseEMBL Heidelberg

Description Immune Profiling of Single Cells...

EMBL Heidelberg

8 February - 12 February 2021

Deep Learning for Image Analysis

Edit

February 08, 2021 00:002021CourseVirtual

Description OverviewSpeakers and TrainersProgrammePractical informationSponsors Overview EMBL is committed to sharing research advances and sustaining scientific interaction throughout the coronavirus pandemic We are delighted to announce that the course is going virtual and invite you to join us online Course Overview The advent of deep learning has brought a revolution in the field of computer vision including most tasks and research questions concerned with microscopy image analysis Neural networks have been successfully used for image restoration classification and segmentation for the detection of objects and characterisation of their morphology for high throughput imaging and large scale processing in 3D Despite these advances training and deployment of such neural networks remains difficult for practitioners of image analysis The aim of our course is to close this gap and teach the participants in the most hands on way possible to apply deep learning based methods to their own data and image analysis problems This is a blended learning course We will begin with 3 pre course sessions on Friday 18 Dec 2020 Friday 15 January 2021 and Friday 29 January 2021 which will bring everyone to a good starting position for a week long intensive virtual course in February 2021 The 3 pre course sessions will have associated homework The week long course in February 2021 will include a few talks but will mostly be devoted to hands on work on real data in small groups of 3 4 participants Audience This course is aimed at both core facility staff and research scientists Prerequisites for this workshop are programming skills in Python and ideally Tensorflow Keras or Pytorch as well as basic knowledge of machine learning theory Participants should provide an outline of one image analysis task they would like to work on during the course Ideally you will provide annotated images for network training during the course Learning Outcomes After this course you should be able to Understand the fundamentals of machine learning methods suitable for image analysis Advise users colleagues in strategies to obtain ground truthTrain and use a CNN for a bioimage analysis task studied in the course Perform simple quality control on the results Speakers and Trainers Anna Kreshuk EMBL Heidelberg Germany Pejman Rasti University of Angers and ESAIP cole Sup rieure Angevine en Informatique France David Rousseau University of Angers France Uwe Schmidt Independent researcher Germany Martin Weigert cole Polytechnique F d rale de Lausanne EPFL Switzerland Valentyna Zinchenko EMBL Heidelberg Germany Trainers Ishaant Agarwal ETH Z rich Switzerland Ali Ahmad INSA Lyon France Mathis Cordier University of Angers France Hadhami Garbouge University of Angers France Joanna Kaczmar Michalska ETH Z rich Switzerland and Tooploox Poland Simon Flyvbjerg N rrelykke ETH Z rich Switzerland Rafal Nowak University of Wroclaw and Tooploox Poland Constanin Pape EMBL Heidelberg Germany Szymon Stoma ETH Z rich Switzerland and Tooploox Poland Mouad Zine El Abidine University of Angers France Scientific Organisers Anna Kreshuk EMBL Heidelberg Germany Course Organiser Tim N rnberger Course and Conference Manager EMBL Heidelberg Germany Programme Got something to say Tweet it with EMBLDeepLearning Day 1 Monday 8 February 2021 TimeSpeaker12 50 13 30 CET 06 50 07 30 EDT Welcome and introductions organisers instructors Anna Kreshuk EMBL Heidelberg GermanyValentyna Zinchenko EMBL Heidelberg GermanyElisabeth Zielonka EMBL Heidelberg GermanyTim N rnberger EMBL Heidelberg GermanyMaryann Heck EMBL Heidelberg GermanyIrena Provaznikova EMBL Heidelberg Germany 13 30 14 15 CET 07 30 08 15 EDT Interactive session Flash talks from participants 2 slides 2 min about yourself your work 14 15 14 30 CET 08 15 08 30 EDT Break14 30 15 15 CET 08 30 09 15 EDT Live talk followed by Q A session 35 min talk plus 10 min Q A Segmentation Anna Kreshuk EMBL Heidelberg Germany 15 15 15 30 CET 09 15 09 30 EDT Break15 30 16 00 CET 09 30 10 00 EDT Introduction to practicals by instructors in Zoom breakout rooms16 00 18 00 CET 10 00 12 00 EDT Practicals in small groups 18 00 18 30 CET 12 00 12 30 EDT Meet the instructors in Zoom breakout rooms18 30 CET 12 30 EDT End of Day 1 Continued access to networking and discussion platform pre recorded lectures and course materials on eCampus Day 2 Tuesday 9 February 2021 TimeSpeaker12 50 13 00 CET 06 50 07 00 EDT Overview of the day13 00 13 45 CET 07 00 07 45 EDT Live talk followed by Q A session 35 min talk plus 10 min Q A Image Restoration and Nuclei DetectionMartin Weigert cole Polytechnique F d rale de Lausanne EPFL SwitzerlandUwe Schmidt Independent researcher Germany13 45 14 15 CET 07 45 08 15 EDT Virtual Social Programme Online Pictionary14 15 14 30 CET 08 15 08 30 EDT Break14 30 14 40 CET 08 30 08 40 EDT Group briefings with instructors in Zoom breakout rooms14 40 16 00 CET 08 40 10 00 EDT Practicals in small groups16 00 16 30 CET 10 00 10 30 EDT Meet the instructors in Zoom breakout rooms16 30 18 00 CET 10 30 12 00 EDT Practicals in small groups continued 18 00 18 30 CET 12 00 12 30 EDT Meet the instructors in Zoom break out rooms18 30 CET 12 30 EDT End of Day 2 Continued access to networking and discussion platform pre recorded lectures and course materials on eCampus Day 3 Wednesday 10 February 2021 TimeSpeaker12 50 13 00 CET 06 50 07 00 EDT Overview of the day13 00 13 45 CET 07 00 07 45 EDT Live talk followed by Q A session 35 min talk plus 10 min Q A Data augmentation strategiesDavid Rousseau University of Angers France13 45 14 15 CET 07 45 08 15 EDT Virtual Social Programme Pub Quiz14 15 14 30 CET 08 15 08 30 EDT Break14 30 14 40 CET 08 30 08 40 EDT Group briefings with instructors in Zoom breakout rooms14 40 16 00 CET 08 40 10 00 EDT Practicals in small groups16 00 16 30 CET 10 00 10 30 EDT Meet the instructors in Zoom breakout rooms16 30 18 00 CET 10 30 12 00 EDT Practicals in small groups continued 18 00 18 30 CET 12 00 12 30 EDT Meet the instructors in Zoom breakout rooms18 30 CET 12 30 EDT End of Day 3 Continued access to networking and discussion platform pre recorded lectures and course materials on eCampus Day 4 Thursday 11 February 2021 TimeSpeaker12 50 13 00 CET 06 50 07 00 EDT Overview of the day and group photo13 00 13 20 CET 07 00 07 20 EDT Live talk followed by Q A session 15 min talk plus 5 min Q A Image classificationValentyna Zinchenko EMBL Heidelberg Germany13 20 13 25 CET 07 20 07 25 EDT Break to switch to next live talk 13 25 13 45 CET 07 25 07 45 EDT Real use case presentation Classification 15 min talk plus 5 min Q A David Rousseau University of Angers France13 45 13 50 CET 07 45 07 50 EDT Break to switch to next live talk 13 50 14 10 CET 07 50 08 10 EDT Real use case presentation Segmentation 15 min talk plus 5 min Q A David Rousseau University of Angers France14 10 14 30 CET 08 10 08 30 EDT Break14 30 14 40 CET 08 30 08 40 EDT Group briefings with instructors in Zoom breakout rooms14 40 16 00 CET 08 40 10 00 EDT Practicals in small groups16 00 16 30 CET 10 00 10 30 EDT Meet the instructors in Zoom breakout rooms16 30 18 00 CET 10 30 12 00 EDT Practicals in small groups continued 18 00 18 30 CET 12 00 12 30 EDT Meet the instructors in Zoom breakout rooms18 30 CET 12 30 EDT End of Day 4 Continued access to networking and discussion platform pre recorded lectures and course materials on eCampus Day 5 Friday 12 February 2021 TimeSpeaker12 50 13 00 CET 06 50 07 00 EDT Overview of the day13 00 15 00 CET 07 00 09 00 EDT Group activity Finish practicals preparation of presentations15 00 15 10 CET 09 00 09 10 EDT Break15 10 16 20 CET 09 10 10 20 EDT Group activity Group presentations Groups 1 3 What worked what didn t what could be done next 20 min per group 16 20 16 30 CET 10 20 10 30 EDT Break16 30 17 40 CET 10 30 11 40 EDT Group activity Group presentations Groups 4 6 What worked what didn t what could be done next 20 min per group 17 40 17 50 CET 11 40 11 50 EDT Break17 50 18 30 CET 11 50 12 30 EDT Interactive Discussion Wrap up18 30 CET 12 30 EDT End of the course Continued access to networking and discussion platform pre recorded lectures and course materials on eCampus for two weeks Got something to say Tweet it with XXX Some pre course work such as watching pre recordings protocol reading and computational exercises with estimated time 0 10 hours will be required and will be shared in advance of the course Some speakers may need to join virtually to give their lecture or Q A and the programme is subject to change All times in the programme below are shown as the time in Europe Berlin Day 3 copy paste TimeSession10 45 11 00Opening remarks11 00 11 15Session11 15 11 45Invited speaker11 45 12 15Invited speaker12 15 12 30Selected short talk12 30 12 45Selected short talk12 30 14 00Lunch14 00 14 15Selected short talk14 15 14 30Selected short talk14 30 14 45Selected short talk14 45 15 00Selected short talk Virtual 15 00 15 15Coffee Break00 00 00 00Session15 15 15 45Invited speaker15 45 16 15Invited speaker16 15 16 30Selected short talk16 30 16 45Selected short talk Day 3 Table Press TimeSession 10 45 11 00Opening remarks 11 00 11 15Session 11 15 11 45Invited speaker 11 45 12 15Invited speaker 12 15 12 30Selected short talk 12 30 12 45Selected short talk 12 30 14 00Lunch 14 00 14 15Selected short talk 14 15 14 30Selected short talk 14 30 14 45Selected short talk 14 45 15 00Selected short talk Virtual 15 00 15 15Coffee Break 00 00 00 00Session 15 15 15 45Invited speaker 15 45 16 15Invited speaker 16 15 16 30Selected short talk 16 30 16 45Selected short talk Practical information Registration Fees and Motivation Letter Application is no longer possible The course was limited to 18 participants The results will be announced approximately 2 weeks after the application deadline Registration Fees included admission course materials and access to computational resources Academia295 EuroPhD Student295 EuroIndustry520 Euro Interested to find more about our upcoming courses Sign up for our events newsletter Follow us on Twitter EMBLEvents or visit our Facebook page to stay up to date with all of our events Financial Assistance Registration Fee Waivers All academic and student registrants are invited to apply for a registration fee waiver provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO The registration fee waiver covers the registration sum that you have paid to attend the meeting Conference participants are not required to pre pay the registration fee to be selected for a fee waiver for a virtual meeting If you have already paid the registration fee and are awarded a fee waiver it will be reimbursed after the meeting Course participants are required to pay the course fee in advance which will then be reimbursed after the recipient has attended the course Childcare Grants For participants and speakers with childcare responsibilities there is the possibility to apply for a grant provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO to offset childcare costs incurred when participating at a virtual event Eligible costs include fees for a babysitter or childcare facility or travel costs for a care giver Please note that priority will be given to early stage researchers Costs will be reimbursed after the meeting only once a reimbursement form and original receipts have been received In order to apply for this grant you must be registered by the abstract submission deadline Boehringer Ingelheim Fonds Travel Grant Applies to selected courses only Availability will be indicated during the abstract or motivation letter submission process This grant covers costs related to your attendance to the course registration travel and accommodation costs The grant is restricted to PhD students and postdocs who conduct basic biomedical research Whether you are eligible to apply for a travel grant depends on when you received your university entrance qualification e g Abitur A Levels High School Diploma Final State Examination for PhD and MD students as well as graduates the university entrance qualification must not have been obtained more than 11 years ago at the time of the envisaged course for postdocs the university entrance qualification must not have been obtained more than 13 years ago at the time of the envisaged course Application Applications for financial assistance can be submitted via the submission portal for the submission of abstracts for conferences or the submission of motivation letters for courses by completing the Financial Assistance Application Section underneath the section for entering abstract motivation letter information The link to the portal can be found in the registration confirmation email that you will receive after registering for the conference or course For conferences if you are not submitting an abstract you can still apply for financial assistance in the submission portal by following the instructions here Note that priority will be given to those submitting an abstract to present at the conference In your application you will be asked to answer questions regarding your motivation for applying and for registration fee waivers the reasons why your lab cannot fund your attendance and how your attendance will make a difference to your career Application for financial support will not affect the outcome of your registration application For some events applications for Childcare Grants will still be done by email Information about the grant will be sent out shortly after the abstract motivation letter deadline Please contact the event Conference Officer if you have any questions Selection The scientific organisers will select the recipients of registration fee waivers during the abstract selection process for conferences and the participant selection process for courses Results will be announced approximately 3 4 weeks before the event start date Selection results do not impact your admission to the meeting Registration fee waiver selection is based on your current work or study location your motivation for applying the reasons for needing financial support and the impact this event will have on your career Childcare grants are allocated based on career stage with priority given to early stage researchers Further details A list of external funding opportunities can be found here and information on attending a conference as an event reporter here For further information about financial assistance please refer to the FAQ page Technical Requirements Below you will find the software and technical requirements for this course Participants are asked to use a laptop with a Mac Linux or Windows operating system not a tablet Chromebook etc and to install a few specific software packages You will need admin rights to be able to install the software on your computer and we recommend you try this before the course If you do not have admin rights please contact your technical support team in advance to make sure the software can be installed Additional Software A classroom application like Zoom will be used for the live talks and Q A sessions More information will be provided closer to the start of the course Other Information While using the software during the course please make sure you have nothing else using your bandwidth We recommend using a wired connection Sponsors Sponsorship Opportunities We offer a variety of event sponsoring possibilities with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget Discounts are available for companies sponsoring multiple events at EMBL Heidelberg View other conferences or contact sponsorship embl de for further information If you are interested in becoming a media partner of this event please visit our media partnerships webpage...

Virtual

1 February - 11 February 2021

EMBL-EBI workshop: University of Pavia, 2021 (Virtual)

Edit

February 01, 2021 00:002021CourseVirtual

Description This series of workshops will explore EMBL EBI data resources for genomics transcriptomics protein sequences structures and interactions and chemical biology Each half day workshop will introduce participants to browsing searching retrieving and conducting a basic analysis of a wide range of biological data types Two workshops will cover the Ensembl genome browser where researchers can explore annotated genomes and features of interest including genes transcripts and variants Participants will also be introduced to the Variant Effect Predictor VEP tool and BioMart for bulk data download Functional genomics resources Array Express Expression Atlas will introduce public data derived from transcriptomics experiments and provide instruction on how to begin investigating biological functions Participants will also cover the Single cell Expression Atlas and the expression data from individual cell sequencing Three workshops will explore resources dedicated to protein data covering UniProt the PDBe IntAct the Complex Portal and Reactome These topics will provide overviews of protein sequence structure and interactions allowing participants to gain a greater understanding of the role played by proteins in the cell The final workshop will cover the EBI s chemical biology resources ChEBI and MetaboLights Participants will learn how to access information on chemical entities of biological interest and the myriad metabolites found in metabolomics experiements Virtual workshop Participants will learn via a mix of pre recorded lectures live presentations and trainer Q A sessions Practical experience will be developed through trainer led demonstrations and personal exercises on each resource Live sessions will be delivered using Zoom with additional support and communication from the host trainer and resource specialists in the chat stream...

Claudia Binda

Virtual

1 February - 5 February 2021

Edit

November 26, 2020 23:002020ConferenceOther

Description The Roaring 20s A New Decade for Life Sciences Virtual...

Other

26 November 2020

Sequence analysis tools in UniProt: BLAST and Align

Edit

November 26, 2020 15:302020WebinarVirtual

Description BLAST and multiple sequence alignments are essential methods commonly used to find and compare protein or nucleotide sequences In this webinar we will demonstrate how you can access and run these sequence analysis tools in UniProt a comprehensive resource of protein sequence and function We will show you how to navigate the results and how you can exploit UniProt protein annotation to expand further the analysis of your results...

Rossana Zaru

Virtual

25 November 2020

Discovering scientific evidence using Europe PMC SciLite annotation

Edit

November 25, 2020 15:302020WebinarVirtual

Description For readers of life sciences journal articles annotations make it easier to scan an article and get a quick overview find key concepts and discover evidence such as gene disease associations or molecular interactions This webinar will demonstrate how to use the power of text mining to find evidence in scientific literature...

Dayane Rodrigues Araujo

Virtual

24 November 2020

Edit

November 09, 2020 17:002020CourseOther

Other

4 November 2020

Variant submission and data access at the European Variation Archive

Edit

November 04, 2020 15:302020WebinarVirtual

Description This webinar will cover how to access data using the EVA UI API and the methodology of variant data submission to the EVA specifically focusing on data transformation and formats With a new version of the variant ID data release now available this webinar will also cover what has been updated and what to expect from future releases...

Baron Koylass

Virtual

4 November - 5 November 2020

Our House is Burning: Scientific and Societal Responses to Mass Extinction – Virtual

Edit

November 04, 2020 00:002020ConferenceVirtual

Description OverviewSpeakers and OrganisersProgramme Overview EMBL is committed to sharing research advances and sustaining scientific interaction throughout the coronavirus pandemic We are delighted to announce that the symposium is going virtual and invite you to join us online The virtual symposium includes talks from invited speakers short talk presenters digital poster sessions and networking opportunities Conference Overview There have been five mass extinctions in Earth s history but are we already in the midst of a sixth At least one million animal and plant species are currently threatened with extinction many within decades a rate unprecedented in human history To what extent however can we measure loss of biodiversity across scales or accurately identify the causes of mass extinction And how will this development affect the planet More importantly perhaps is the question of whether scientific and societal interventions can effectively tackle this issue Will initiatives such as the UN s Decade on Ecosystem Restoration really provide solutions to the problem The 21st EMBL Science Society Conference in 2020 seeks to address these questions It will consider the impact of environmental changes on biodiversity ecosystem services and human well being Crucially it will focus on potential solutions and types of action from activism to political strategies and from local grass roots conservation groups to global youth movements It will also evaluate the application of various targeted intervention methods across data science emerging technologies sustainability solutions and beyond Session Topics The Anthropocene extinction scientific overviewThe environmental and societal impact of mass extinctionScientific societal and technological responses to mass extinction For more information about previous meetings in this series please check the Science and Society Website What past participants say about the conference A scientist must find time to step away from the lab table and question scientific practices more broadly Without conferences like these we would lack a forum to do so and would be blind toward potential improvements Joshua Yudice Brandenburg University of Technology Germany The event was greatly organized and very interesting All the speakers presentations were outstanding and the discussions very stimulating I loved the possibility to talk to the speakers during the social moments Anna Sofia Tascini IRCCS Ospedale San Raffaele Italy Speakers and Organisers Keynote Speakers Michael Benton University of Bristol UK Frank Pope Save the Elephants Kenya Speakers Marlow Baines Earth Guardians USA Elinor Breman Royal Botanic Gardens Kew UK Hans de Kroon Radboud University The Netherlands V ctor de Lorenzo National Center for Biotechnology Spain Ted Hyman ZGF Architects USA Roberto Kolter Harvard University USA Henri Landes Sciences Po France Yadvinder Malhi University of Oxford UK Vanessa Nakate Rise Up Movement Uganda Benki Piy ko Community leader of Apiwtxa Brazil Andy Purvis Natural History Museum UK Katja Tielb rger University of T bingen Germany Diana H Wall Colorado State University USA Expert Panel Elizabeth Maruma Mrema Panel Talk UN Convention on Biological Diversity Canada Kiran R Patil Panel member EMBL Heidelberg Germany Brendan Rouse Panel member and chair EMBL Heidelberg Germany Lara Urban Panel member University of Otago New Zealand Session Chairs Holger Breithaupt EMBO Reports Germany Manuel Carbajo Martinez EMBL EBI Hinxton UK Sara Formichetti EMBL Rome Italy Cornelius Gross EMBL Rome Italy Edith Heard Director General of EMBL Germany Organising Committee Edith Heard EMBL Germany Plamena Markova EMBL Germany Halld r Stef nsson External Nassos Typas EMBL Germany Verena Visario EMBL Germany Lucia von Bredow EMBL Germany Chair Science and Society Manager Lucia von Bredow EMBL Heidelberg Germany Conference Organisers Programme 21st EMBL Science and Society Conference Our House is Burning Scientific and Societal Responses to Mass Extinction Virtual Programme...

Lucia von Bredow

21st EMBL Science and Society Conference

Virtual

3 November 2020

Europe PMC: Programmatic access

Edit

November 03, 2020 14:002020WebinarVirtual

Description Europe PMC is an open repository providing access to worldwide biomedical literature including articles preprints books patents and clinical guidelines This webinar will introduce the Europe PMC Articles RESTful API and show how to programmatically access publications and related information such as citations references data links or text mined terms...

Dayane Rodrigues Araujo

Virtual

2 November - 6 November 2020

Metagenomics bioinformatics (Virtual)

Edit

November 02, 2020 00:002020CourseVirtual

Description Gain knowledge of the tools processes and analysis approaches used in the field of metagenomics This course will cover the metagenomics data analysis workflow from the point of newly generated sequence data Participants will explore the use of publicly available resources and tools to manage share analyse and interpret metagenomics data The content will include issues of data quality control and how to submit to public repositories While sessions will detail marker gene and whole genome shotgun WGS approaches the primary focus will be on assembly based approaches Discussions will also explore considerations when assembling genome data the analysis that can be carried out by MGnify on such datasets and what downstream analysis options and tools are available Virtual course The course content will involve participants learning via pre recorded lectures live presentations and trainer Q A sessions Practical experience will be developed through group activities and computational exercises Sessions will be delivered over Zoom with additional text communication over Slack Trainers will be available to assist answer questions and further explain the analysis during these times Computational practicals will be run in Docker containers operating on EMBL EBI s virtual training infrastructure this means there is no need to have a powerful computer to run exercises or a requirement to install complex software before the course Participants will need to be available between the hours of 09 00 17 00 GMT each day of the course...

Marina Pujol

Virtual

29 October 2020

Introducing the new UniProt Disease Portal

Edit

October 29, 2020 15:302020WebinarVirtual

Description This webinar will provide an interactive introduction to the new UniProt Disease Portal a single centralised resource of UniProt disease centric information which has been developed with the help of our users to better serve the needs of the research community and facilitate protein discoverability The UniProt knowledgebase UniProtKB supports biomedical research by providing a comprehensive high quality and freely accessible resource of protein sequence and functional information To do this UniProt integrates interprets and standardises data from a range of sources including scientific literature protein sequence analysis tools other databases and automatic annotation systems to provide a detailed overview of the available protein knowledge This webinar will introduce you to the UniProt Disease Portal which aims to help researchers explore and access current genomic disease related data from the UniProtKB database but in a single centralised resource The portal incorporates UniProt functional annotations protein network visualisations genomic variant and drug related data and organises in a way that allows users to easily visualise and compare data to identify similarities using variants protein interactions diseases and drug data The Disease Portal is currently in its first beta release so we hope that this interactive introduction will give you an understanding of how to access disease centric protein data in UniProt and encourage your feedback to assist ongoing development of the Portal to further suit the requirements of our users...

Kate Warner, Emily Bowler-Barnett

Virtual

No matching events found; Reset your filters.