
John Moran
University of Michigan
USA
EMBO Workshop
Abstract submission for posters are possible. Please contact Diah Yulianti at diah.yulianti@embl.de for more info.
This conference will take place at EMBL Heidelberg, with the option to attend virtually. Please see EMBL’s COVID-19 safety recommendations if attending the on-site event.
This conference assembles world-leading experts from diverse fields including genomics, epigenetics, structural biology, developmental biology, immunology, cancer biology, and neurobiology to discuss the broad impacts of transposable elements (TEs) on organismal biology. The meeting provides a venue for cross-disciplinary discussions, with the goal of catalysing inter-disciplinary collaborations to address emerging questions in these scientific fields.
Although often disparaged as “junk” DNA, it is now undeniable that TE activity has significantly shaped the structure and function of all genomes, ranging from bacteria to humans. TEs are major drivers of genetic diversity and contribute to human disease. Remarkably, TE-derived sequences are also often co-opted by the host to play important roles in gene expression, early development, immunity, neuronal diversification, and, perhaps, aging.
Institute of Molecular Biology
Germany
NYU Grossman School of Medicine
USA
Queen Mary University of London
UK
Institute of Molecular Biotechnology
Austria
University of Neuchâtel
Switzerland
Institute of Integrative Biology of the Cell (I2BC)
France
Institut Jacques Monod
France
The University of Queensland
Australia
University of Cambridge
UK
Université Paris-Saclay
France
University of Rochester
USA
University of Cambridge
UK
Lund University
Sweden
Max Planck Institute of Molecular Plant Physiology
Germany
University of Cambridge
UK
Kyoto University
Japan
Princeton University
USA
Imperial College London
UK
Cornell University
USA
Liverpool John Moores University
UK
Mater Research Institute
Australia
Massachusetts Institute of Technology
USA
UMass Chan Medical School
USA
Institut Curie
France
Institute of Molecular Biotechnology
Austria
The University of Edinburgh
UK
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Time (Europe/Berlin) | Speaker |
---|---|
11:00 – 12:45 | Registration and Lunch |
12:45 – 13:00 | Opening remarks Scientific Organisers |
13:00 – 14:00 | KEYNOTE LECTURE 1 Susan R. Wessler – University of California, Riverside, USA |
14:00 – 18:15 | SESSION 1 Genomics and evolution |
14:00 – 14:30 | Genome-wide epigenetic regulation of mammalian TEs and impact on brain and cancers Geoff Faulkner – University of Queensland, Australia |
14:30 – 14:45 | Evolution of gene regulation by species-specific transposable elements in primates Mari Ohnuki – Kyoto University, Japan |
14:45 – 15:00 | Protein domains from multigene families recurrently associate with domains derived from transposable elements and viruses Miguel Vasconcelos Almeida – University of Cambridge, UK |
15:00 – 15:30 | How horizontal transfer of retrotransposons impacts transgenerational memory Coleen Murphy – Princeton University, USA |
15:30 – 16:00 | Coffee break and meet the speakers |
16:00-16:15 | Exploring the contribution of transposable elements to the evolution of salamander developmental and regenerative programs Diego Rodriguez Terrones – Research Institute of Molecular Pathology, Austria |
16:15 – 16:45 | TEs and the rapid evolution of plant pathogens Daniel Croll – University of Neuchatel, Switzerland |
16:45 – 17:15 | Dynamic interplay between TEs and mammalian genomes and their impact on evolution Sandra Richardson – Mater Institute, Australia |
17:15 – 17:30 | The Silent Architects of Yeast Genome Aleksandras Konovalovas – Vilnius University, Life Sciences Centre, Institute of Biosciences, Lithuania |
17:30 – 17:45 | The transcriptional repertoire of transposable elements during mammalian preimplantation development Marlies Oomen – Helmholtz Zentrum Munich Germany |
17:45– 18:15 | Horizontal transfer of TEs Clément Gilbert – Paris-Saclay University, Gif sur Yvette, France |
18:15 – 19:45 | Dinner |
19:45 – 21:45 | Welcome reception |
Time (Europe/Berlin) | Speaker |
---|---|
08:15 – 09:00 | Meet the editor |
09:00 – 10:30 | SESSION 2 Transposon regulation |
09:00 – 09:30 | Evolution of KZFPs and host-TE interactions Michael Imbeault – University of Cambridge, UK |
09:30-09:45 | Novel actors involved in chromatin-associated TE control in embryonic stem cells Emeline Roger – Institut Curie France |
09:45 – 10:15 | Epigenetic regulation of TEs in plants Angélique Deleris – I2BC, Gif sur Yvette, France |
10:15 – 10:30 | Comprehensive investigation of de novo insertions in piRNA clusters reveals dual functions of Panoramix in the piRNA pathway. Yicheng Luo – California Institute of Technology United States of America |
10:30 – 11:00 | Coffee break and meet the speakers |
11:00 – 11:30 | Role of TEs in plant reproduction Claudia Kohler – Max Planck Institute of Molecular Plant Physiology, Germany |
11:30 – 12:00 | Regulation of TEs in the mammalian germline Joan Barau – IMB Mainz, Germany |
12:00 – 12:15 | Young & hot L1s in the human genome evade the host restriction factor TEX19 Ricky Padilla Del Valle – University of Washington United States of America |
12-15-12:30 | Flash Talks 1 |
12:30 – 14:00 | Lunch and meet the speakers |
14:00 – 16:00 | Poster session 1 |
16:00 – 16:30 | Role of TEs in genome rearrangements Sandra Duharcourt – Institut Jacques Monod, France |
16:30-16:45 | Recurrent molecular adaptation revealed by systematic cross-species protein interaction analyses of the Drosophila piRNA pathway Sebastian Riedelbauch – Aarhus University Denmark |
16:45-17:00 | A direct protein-protein interaction network of cytoplasmic Drosophila piRNA pathway factors Mandy Jeske – Heidelberg University Germany |
17:00-17:30 | PiRNA-mediated TE control in mammals Philip Zamore – University of Massachusetts Medical School, USA |
17:30-17:45 | A co-opted retroviral capsid defines a rapidly-evolving architectural protein family that binds to transposable elements Wayo Matsushima – École Polytechnique Fédérale de Lausanne (EPFL), Switzerland |
17:45-18:00 | Flash Talks 2 |
18:00 – 18:30 | Coffee break and meet the speakers |
18:30 – 19:00 | Small RNA control of TEs and repetitive DNA in flies Yukiko Yamashita – MIT, Cambridge, USA |
19:00 – 19:30 | The impact of active TEs on aging Vera Gorbunova – University of Rochester, USA |
19:30 – 19:45 | Transposon silencing in duckweeds, lessons from non-model organisms Arturo Mari-Ordonez – Gregor Mendel Institute of Molecular Plant Biology Austria |
19:45 – 20:00 | Structural and biochemical insights on the role of HUSH component MPP8 in transposon regulation Yorgo Modis – University of Cambridge United Kingdom |
20:00 – 21:30 | Dinner |
21:00 – 22:30 | After dinner drinks |
Time (Europe/Berlin) | Speaker |
---|---|
09:00 – 13:00 | SESSION 3 Transposition mechanisms |
09:00 – 09:30 | How phages and mobile chromosomal islands promote bacterial pathogenicity Jose Penades – Imperial College London, UK |
9:30-9:45 | Structure-function analysis of mammalian tRNA-derived SINEs Emily Koch – University of Michigan United States of America |
09:45 – 10:15 | A network of interferon-stimulated genes inhibits human LINE-1 retrotransposition Tomoichiro Miyoshi – University of Kyoto, Japan |
10:15 – 10:30 | Extrachromosomal Circular DNA Reveals Helitron Activity in Wheat Etienne Bucher – Agroscope Switzerland |
10:30 – 11:00 | Coffee break and meet the speakers |
11:00 – 11:30 | Regulation of site-specific recombination by large serine integrases Femi Olorunniji – Liverpool John Moores University, UK |
11:30-11:45 | From retroelements to retroviruses: the evolutionary plasticity of reverse-transcribing RNA viruses Haoming Zhai – University of Cambridge United Kingdom |
11:45 – 12:15 | Mechanisms and diversity of CRISPR-guided DNA transposition systems Joseph Peters – Cornell University, USA |
12:15 – 12:30 | The genetic and environmental basis of heritable transposition in Arabidopsis thaliana Mireia Bueno Merino – IPS2 – Paris – Saclay University France |
12:30 – 12:45 | Genomic integration of SARS-CoV-2 sequences in virus infected and viral RNA transfected human cells and infection of bat iPS cells with virus Rudolf Jaenisch – Whitehead Institute USA |
12:45 – 14:00 | Lunch and meet the speakers |
14:00 – 19:30 | SESSION 4 Physiological impacts |
14:00 – 14:30 | Evolution of TE-driven regulatory networks Miguel Branco – Queen Mary University of London, UK |
14:30 – 15:00 | Mobile toxin-antidote systems Alejandro Burga – IMBA, Austria |
15:00 – 15:30 | Coffee break and meet the speakers |
15:30– 16:30 | KEYNOTE LECTURE 2 Studies of a human retrotransposable element John Moran – University of Michigan, Ann Arbor, USA |
16:30 – 17:30 | Panel Discussion on emerging topics in TE biology |
17:30 – 19:30 | Poster session 2 |
19:30 – 21:00 | Dinner |
21:00 – 24:00 | Party |
Time (Europe/Berlin) | Speaker |
---|---|
09:00 – 13:30 | SESSION 4 Physiological impacts |
09:00 – 09:15 | Co-opted endogenous retrovirus governed Pregnancy Specific Glycoprotein 9 (PSG9) locus coordinates trophoblast differentiation in human placentation Zsuzsanna Izsvak – Max Delbrück Center Germany |
09:15 – 09:45 | Metastable TEs in mammals and the environment Anne Ferguson Smith – University of Cambridge, UK |
09:45 – 10:00 | Helitron-derived repeat structures regulate transgenerational inheritance in C. elegans Faisal Alkhaldi – King Abdullah University of Science and Technology (KAUST), Saudi Arabia |
10:00 – 10:15 | Building mouse models of human retrotransposon insertions Jef Boeke – NYU Grossman School of Medicine, USA |
10:15 – 10:30 | Reverse Transcriptase-Related Genes at the Intersection of Environmental Stress Responses Irina Arkhipova – Marine Biological Laboratory, USA |
10:30 – 11:00 | Somatic LINE retrotransposition in motorneurons has functional consequences Thomas Widmann – FIBAO (Fundación de Investigación Biosanitaria) & GENYO – Centre for Genomics and Oncological Research Spain |
11:00 – 11:30 | Coffee break and meet the speakers |
11:30-11:45 | Retroviral-like particles inducing cell death drive a limb developmental malformation Juliane Glaser – Max Planck Institute for Molecular Genetics Germany |
11:45 – 12:15 | Impact of TEs in brain physiology Johan Jakobsson – Lund University, Sweden |
12:15 – 12:30 | The Drosophila retrotransposable element Copia regulates larval neuromuscular junction physiology. Peter M’Angale – University of Massachusetts Chan Medical School United States of America |
12:30 – 12:45 | Endogenous retroviruses wrestle with epigenetic surveillance to drive host pathophysiology Yejing Ge – MD Anderson Cancer Center United States of America |
12:45 – 13:15 | Epigenetic mechanisms of TE repression Eric Miska – University of Cambridge, UK |
13:15 – 13:30 | Closing remarks |
13:30 – 14:00 | Packed lunch and departure |
Abstract submission for posters are possible. Please contact Diah Yulianti at diah.yulianti@embl.de for more info.
On-site registration fees include admission, conference materials, COVID-19 safety measures, meals and coffee breaks. Participants are expected to book and pay their own accommodation and travel expenses.
Virtual registration fees include access to all of the talks (livestreamed and on demand) and facility to submit questions.
On-site Academia | €450 |
On-site PhD Student | €350 |
On-site Industry | €750 |
Virtual Academia | €175 |
Virtual PhD Student | €125 |
Virtual Industry | €225 |
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Hello | Hallo |
Goodbye | Tschüss |
Good morning | Guten Morgen |
Good afternoon | Guten Tag |
Good evening | Guten Abend |
Good night | Gute Nacht |
I’m sorry | Es tut mir leid |
Excuse me… | Entschuldigen Sie |
How are you? | Wie geht’s? |
I’m fine thanks. And you? | Mir geht es gut , danke, und dir/Ihnen? |
What is your name | Wie heisst du? Wie heissen Sie? |
My name is | Ich heisse |
Do you speak English | Sprechen Sie Englisch? |
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Please speak more slowly | Können Sie bitte langsamer sprechen |
Thank you | Dankeschön |
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The menu, please | Die Speisekarte, bitte |
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I’m Vegetarian | Ich bin Vegetarier |
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Media partners
EMBO reports, an EMBO Press journal
International Union of Biochemistry and Molecular Biology
FEBS Open Bio, a FEBS Press journal
Bio Essays, a Wiley Online Library
Advanced Biology, a Wiley Online Library
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We offer a variety of event sponsoring possibilities, with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget. Discounts are available for companies sponsoring multiple events at EMBL Heidelberg. View other conferences, or contact sponsorship@embl.de for further information on sponsoring possibilities.
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Date: 8 - 11 Nov 2023
Location: EMBL Heidelberg and Virtual
Venue: EMBL Advanced Training Centre
Deadline(s):
Abstract submission: Closed
Registration (On-site): 12 Oct 2023
Registration (Virtual): 1 Nov 2023
Organisers:
Contact: Diah Yulianti
EMBL Courses and Conferences are kindly supported by our Corporate Partnership Programme