EMBO | EMBL Symposium
This conference will take place at EMBL Heidelberg, with the option to attend virtually. Proof of COVID-19 vaccination or recovery is required for on-site attendance. Please see EMBL’s COVID-19 safety policy for on-site events.
Phase separation is emerging as a common biophysical basis underlying many important cellular functions. This conference will bring together scientists from soft matter, polymer physics, molecular biology, structural biology, and cell and developmental biology to study condensates in biology and disease. Goals are
“I have never been to a conference where every single talk was relevant, exciting, and well done. This is particularly phenomenal given the interdisciplinary nature of this field.” – Carlos Castaneda, Syracuse University, USA
“Although Intrinsically Disordered Proteins and Phase Separation have been around for a number of years, this meeting felt like the kick-off for a novel area in molecular biology.” – Roland Dosch, University Medical Center Göttingen, Germany
“This was the best conference I have attended in years, bringing together biophysicists and biologists in an exciting and challenging format. I learnt a lot and have made great contacts for new collaborations.” – Sarah Mizielinska, Kings College London, UK
St. Jude Children’s Research Hospital
Centre for Genomic Regulation
University of Padova
Max Planck Institute for Biophysical Chemistry
Max Planck Institute for the Science of Light
Washington University in St. Louis
Institute of Biology Valrose
Institute of Molecular Biology
Max Perutz Labs Vienna
Chinese Academy of Sciences
Université de Montréal
Johns Hopkins University
Max Planck Institute of Molecular Cell Biology and Genetics
TU Dresden and Max Planck Institute of Molecular Cell Biology and Genetics
IMB & JGU Mainz
IMB & JGU Mainz
Got something to say? Tweet it! #EESPhaseSeparation
|12:30 – 14:00||Registration and Lunch|
|14:00 – 14:15||Opening remarks by scientific organisers|
|14:15 – 17:45||Session 1: Diverse functions and dysfunctions of condensates|
Session chair: tbc
|14:15 – 15:15||Keynote lecture:|
RNA granule biology and roles in disease
Paul Taylor – St. Jude Children’s Research Hospital, USA
|15:15 – 15:45||Coffee Break|
|15:45 – 16:10||Multiscale modelling of chromatin phase separation|
Rosana Collepardo Guevara – University of Cambridge, UK
|16:10 – 16:35||Miscibility and Immiscibility of ALS-FUS mutant Condensate|
Sua Myong – Johns Hopkins University, USA
|16:35 – 17:00||The mechanics of chromatin evolution, adaptation and design|
Stephen Micknick – Université de Montréal, Canada
|17:00 – 17:25||Protein Disorder in regulation of chromosome surface properties|
Cuylen-Häring – EMBL Heidelberg, Germany
|17:25 – 17:45||Flash talks (approx. 10 á 2 min)|
|17:45 – 19:15||Poster Session 1 (odd numbers)|
|19:15 – 20:45||Dinner at EMBL Canteen|
|20:45 – 22:15||Social Event tbc|
|09:15 – 12:00||Session 2: Polymer perspective on phase separation|
session chair: tbc
|09:15 – 09:40||Sequence-based prediction of biomolecular condesates and mutations disrupting membraneless organelles|
Monika Fuxreiter – University of Padova, Italy
|09:40 – 10:05||A stickers and spacers model for phase separation of low complexity domains|
Alex Holehouse – Washington University in St. Louis, USA
|10:05 – 10:20||Selected #1|
|10:20 – 10:35||Selected #2|
|10:35 – 10:50||Selected #3|
|10:20 – 10:50||Coffee Break and Meet the speakers|
|10:50 – 11:15||Speaker to be announced|
|11:15 – 11:30||Selected #4|
|11:30 – 11:45||Selected #5|
|11:45 – 12:00||Selected #6|
|12:00 – 13:30||Lunch|
|13:30 – 00:00||Session 3:Biophysics and advanced techniques|
Session chair: tbc
|13:30 – 13:55||Advanced biophotonics tools to quantify biological phase transitions|
Jochen Guck – Max Planck Institute for the Science of Light, Germany
|13:55 – 14:20||Coacervates as models for membrane-free condensates|
Dora Tang – Max Planck Institute of Molecular Cell Biology and Genetics, Germany
|14:20 – 14:50||Coffee Break and Meet the speakers|
|14:50 – 15:05||Selected #7|
|15:05 – 15:20||Selected #8|
|15:20 – 15:35||Selected #9|
|15:35 – 15:50||Selected #10|
|15:50 – 16:05||Selected #11|
|16:05 – 16:25||Flash talks (approx. 10 á 2 min)|
|16:25 – 18:00||Poster Session 2 (even numbers)|
|09:15 – 12:20||Session 4: Phase separation in development|
Session chair: tbc
|09:15 – 09:40||A novel membrane-less organelle required for paternal epigentic inheritance|
René Ketting – IMB Mainz, Germany
|09:40 – 10:05||Multiscale multiphase condensates buffer repressed mRNAs to promote|
robust translation control
Arnaud Hubstenberger – Institute of Biology Valrose, France
|10:05 – 10:30||Novel membraneless organelles in oocytes: Endo-Lysosomal Vesicular Assemblies (ELVAs)|
Elvan Böke – Centre for Genomic Regulation, Spain
|10:30 – 11:00||Coffee Break and Meet the speakers|
|11:00 – 11:25||Selected #12|
|11:25 – 11:40||Selected #13|
|11:40 – 11:55||Selected #14|
|11:55 – 12:20||Selected #15|
|12:20 – 12:45||Selected #16|
|12:20 – 12:40||Lunch to go|
|12:45 – 17:00||Free afternoon and sightseeing|
|17:00 – 00:00||Session 5: Function and regulation of phase separation|
Session chair: tbc
|17:00 – 17:25||Super-resolution imaging of transcription in live mammalian cells|
Ibrahim Cissé – Max Planck Institute of Immunobiology and Epigenetics, Germany
|17:25 – 17:50||Transcription factor condensation and nucleo-cytoplasmic partitioning|
Lucia C. Strader – Duke University, USA
|17:50 – 18:15||The role of liquid-liquid phase separation in nuclear ubiquitin signalling|
Alwin Köhler – Max F. Perutz Laboratories, Austria
|18:15 – 18:40||Tetsuro Hirose – Osaka University, Japan|
|18:40 – 19:05||The life of an mRNA is controlled by DEAD-box ATPases|
Karsten Weis – ETH Zurich, Switzerland
|19:05 – 20:35||Dinner at EMBL Canteen|
|20:35 – 22:00||Social Event tbc|
|09:15 – 12:20||Session 6: Protein structure in the condensed state|
Session chair: tbc
|09:15 – 09:40||Underpinning structural reorganisation in cellular stress response|
Julia Mahamid – EMBL Heidelberg, Germany
|09:40 – 10:05||Seeing the atomic determinants of phase separation in function and disease|
Nicolas Fawzi – Brown University, USA
|10:05 – 10:20||How chaperones regulate protein phase separation in membrane-less organelles|
Cong Liu – Chinese Academy of Sciences, China
|10:20 – 11:05||Coffee Break and Meet the speakers|
|11:05 – 11:20||Selected #17|
|11:20 – 11:35||Selected #18|
|11:35 – 11:50||Selected #19|
|11:50 – 12:05||Selected #20|
|12:05 – 12:20||Selected #21|
|12:20 – 12:35||Selected #22|
|12:35 – 14:05||Lunch|
|14:05 – 14:30||The selective phase of nuclear pore complexes|
Dirk Görlich – Max Planck Institute for Biophysical Chemistry, Germany
|14:30 – 14:45||Selected #23|
|14:45 – 15:00||Selected #24|
|15:00 – 15:45||Coffee Break and Meet the speakers|
|15:45 – 16:00||Selected #25|
|16:00 – 16:15||Selected #26|
|16:15 – 16:30||Selected #27|
|16:30 – 16:45||Feedback Survey Session (Q&A)|
|16:45 – 17:15||Coffee Break and Meet the speakers|
|17:15 – 18:15||Keynote lecture: RNA granule biology and roles in disease|
Clifford P. Brangwynne – Princeton University, USA
|18:15-18:30||Closing remarks and Poster prizes|
|18:30 – 20:30||Dinner at EMBL Canteen|
|20:30 – 23:30||Social event tbc|
On-site Registration Fees include admission, conference materials, COVID-19 safety measures, meals and coffee breaks. Participants are expected to book and pay their own accommodation and travel expenses.
Virtual Registration Fees include access to all of the talks (livestreamed and on demand) and facility to submit questions.
|On-site PhD Student||€600|
|Virtual PhD Student||€125|
NO visa support letters will be issued until payment of the registration fee is confirmed.
Accredited journalists may be eligible to register for a reduced press rate or in some cases for complimentary registration. Registrants may be required to provide accreditation or equivalent proof of press membership after registration. Please contact Lea Hohmann for more information.
Registration will be on a first-come first-served basis. Your place can only be confirmed after payment of the registration fee. If you are added to our waiting list, please consider taking advantage of our offerings to participate virtually.
On-site participants: Types of payments accepted are international bank transfers and credit card payments.
Virtual participants: We are only able to accept card payments. In exceptional cases we can accept bank transfers. Please contact email@example.com for details.
Only registered participants attending the on-site event are eligible to submit an abstract. Abstracts will not be accepted from virtual participants.
After you have logged in and successfully registered, you will receive an email asking you to submit your abstract. Click on the link provided and enter your abstract in the text box provided. Alternatively you can submit your abstract by clicking on the link on the confirmation page directly after registering. The same login credentials are used for both processes.
Title: The title should not exceed 20 words. Only the first word of the title should start with a capital letter and the rest of the title should be in lowercase.
Authors and Affiliations: Please fill in the author’s details as requested in the online form. The compulsory details are: First Name, Last Name, Organisation Name (Affiliation or Company), Country and Email. Mark only one author as the role of First author and please don’t forget to indicate who will be presenting. The order of the authors will be listed as follows: First Author, Co-First Author (alphabetically if multiple), co-author(s) (in the order added by the submitter).
Presentation Types: When submitting your abstract, you can apply for an oral or poster presentation. A selection process will take place with the results announced 2-3 weeks after the abstract submission deadline.
Please check our FAQs pages for further information on how to submit an abstract.
Limited financial assistance is provided by the EMBL Advanced Training Centre Corporate Partnership Programme and EMBO in the form of both registration fee waivers and travel grants. Availability is limited to participants attending on-site events in Heidelberg and will be indicated during the abstract or motivation letter submission process.
Your place in the meeting is only confirmed by paying the registration fee, which is mandatory even when receiving a fee waiver.
The fee waiver will cover the registration sum that you have paid to attend the course or conference.
The travel grant will cover the cost of travel (airfare, train, bus, taxi, accommodation, visa, and/or registration fees*) and is provided up to specified caps which are normally as follows:
– up to €400 for participants travelling to an EMBL Course, EMBL Conference or EMBO|EMBL Symposium from within Europe.
– up to €1000 for participants travelling to an EMBL Course, EMBL Conference or EMBO|EMBL Symposium from outside Europe.
– up to €500 for any participant travelling to an EMBO Practical Course or EMBO Workshop.
– up to €1000 for any participant working in Chile, India, Singapore or Taiwan travelling to an EMBO Practical Course or EMBO Workshop.
*Registration fees are only covered for EMBO Practical Courses or EMBO Workshops
The organisers may reduce the grant cap to accommodate more participants. Recipients will be notified of their travel cap amount when they are informed of the outcome of their application. Original receipts must be provided with your signature for all costs incurred within two months of completion of travel. Scanned copies cannot be accepted.
You may apply for financial assistance when submitting your motivation letter for courses, and abstract for conferences. In your application you will be asked to answer questions regarding why your lab cannot fund your attendance and how your attendance will make a difference to your career. Application for financial support will not affect the outcome of your registration application.
For the Boehringer Ingelheim Fonds Travel Grant, there is a pre-application question during the motivation letter submission process, and if selected you will be requested to complete a standard form and documentation consisting of your travel expense estimation.
The scientific organisers will select the recipients of all financial assistance during the motivation letter or abstract selection process. Results will be announced approximately 6-8 weeks before the event start date, however for some events this may be delayed. Selection results do not impact your admission to the meeting. Selection is based on your current work or study location, the reasons for needing financial support and the impact this event will have on your career.
Costs will be reimbursed after the meeting only once a reimbursement form and original receipts (from travel costs) have been received.
For further information about financial assistance please refer to the FAQ page.
Accommodation is not included in the conference registration fee.
As further changes in our events are possible due to COVID-19, you should book flights, trains and hotels with flexible options and favourable cancellation conditions.
The hotels below have rooms on hold for participants until 7 April 2022, in some cases at special rates. Please quote the booking code EES22-04 and confirm the exact price of the room with the hotel directly.
|Hotel Anlage||Hotel ibis Heidelberg||Premier Inn Heidelberg City|
|Hotel Bayrischer Hof||ISG Hotel||Staycity Aparthotel Heidelberg|
|B&B Hotel||Leonardo Hotel Heidelberg City Centre||Steffi’s Hostel Heidelberg|
|Exzellenz Hotel & Boarding House||Meininger Heidelberg||Hotel Vier Jahreszeiten Heidelberg|
|Hotel Holländer Hof||Hotel Monpti|
Conference shuttle buses are free of charge for participants, and depart from designated bus stops near the hotels to EMBL and back, mornings and evenings.
The bus stops for this conference are:
View Conference shuttle bus stops and hotels in a larger map. Please note that not every bus stop will be used for every event.
Address: EMBL, Meyerhofstraße 1, 69117 Heidelberg, Germany. For further information on getting to EMBL Heidelberg visit Public Transportation to the Venue. For information about accommodation and local transportation please refer to the FAQ page.
All meals and coffee breaks are included in the registration fee. Our catering staff will prepare a wide variety of vegetarian meals, meat and fish dishes, soups, pasta, fresh fruit and vegetables, as well as a variety of desserts.
Please wear your badge at all times when serving yourself.
No food or drinks are allowed in the auditorium.
There are lockers available next to the stairs leading down into the Auditorium. You will find some of those equipped with sockets to charge your smartphone/tablet etc.
In most places the electricity is 220 volts AC (50 cycles). An adaptor and a plug that fits the German socket may be needed for your appliances/laptop (i.e. American, Japanese, etc.). A USB charging station for electronic devices is available at the registration desk.
EMBL Merchandise is available on Mon – Thu (9 am – 12 pm). If you are interested in purchasing an EMBL souvenir (products presented in the glass display in the registration area), please ask at the registration desk for more information.
Please read EMBL’s COVID-19 terms and conditions for events.
Do not smoke in any EMBL building.
Eating and drinking is prohibited in the Auditorium and all laboratories.
Do not enter any restricted areas or the laboratories unless instructed to do so.
If first aid is required …
In case of fire …
Beyond first aid…
Please remember to bring your own medication, if needed, to the conference. Note that the next pharmacy is a 4-minute drive from the EMBL, but for many medications you will be required to see a doctor to get a prescription.
Ensure in advance that your medical insurance will cover you during your visit in the event that you do need to see a doctor while in Heidelberg. In any case, the EMBL Course and Conference Office will assist you to get to the pharmacy and a doctor of your choice if necessary.
Wi-Fi is available everywhere on the premises (no password required), just log on to ATC-Guest. The eduroam network (secure, world-wide roaming access service developed for the international research and education community) is also available.
‘’Lost and Found’’ are kept at the registration desk until the end of the conference.
There are lockers available on-site to store your luggage, which require a 2 EURO coin to operate. There is another luggage room on level E0, which is free to use but remains unlocked during the conference.
There is a nursing room available in the ATC Rooftop Lounge on level A29.
During the conference an EMBL Photographer may be taking photographs. If you would not like to appear in these, please inform the photographer or a member of the Course and Conference Office.
We can help printing your boarding passes/train ticket. Please send it to firstname.lastname@example.org and collect your print-outs at the registration desk.
There is a room for prayer, mediation and yoga located on level E0 behind the Auditorium. Please be respectful of other participants using the room.
A variety of activities in Heidelberg can be found on this website: www.heidelberg-marketing.com
During the event we provide conference shuttle busses to and from EMBL. In addition, there is the public bus 39A that serves the EMBL campus and taxis can be easily booked at any time. Information on the conference shuttle busses can be found on the individual event website and more detailed information on travelling to EMBL can be found on our Travel Information page.
|Good morning||Guten Morgen|
|Good afternoon||Guten Tag|
|Good evening||Guten Abend|
|Good night||Gute Nacht|
|I’m sorry||Tut mir leid|
|Excuse me…||Entschuldigen Sie|
|How are you?||Wie geht’s?|
|I’m fine thanks. And you?||Mir geht es gut , danke, und dir/Ihnen?|
|What is your name||Wie heisst du? Wie heissen Sie?|
|My name is||Ich heisse|
|Do you speak English||Sprechen Sie Englisch?|
|I don’t understand||Ich verstehe nicht|
|Please speak more slowly||Können Sie bitte langsamer sprechen|
|Thank you||Danke schön|
|Where is the toilet?||Wo ist die Toilette?|
|Please call me a taxi||Bitte rufen Sie mir ein Taxi|
|How do I get to….?||Wie komme ich zum/zur…..?|
|A beer/two beers, please||Ein Bier/zwei Bier bitte|
|A glass of red/white wine please||Ein Glas Rot/Weisswein bitte|
|The menu, please||Die Speisekarte, bitte|
|Is there a local speciality?||Gibt es eine Spezialität aus dieser Gegend?|
|I’m Vegetarian||Ich bin Vegetarier|
|It was delicious||Es war hervorragend|
|The bill, please||Die Rechnung, bitte|
|I have a headache||Ich habe Kopfschmerzen|
|I have a sore throat||Ich habe Halsschmerzen|
|My stomach hurts||Ich habe Magenschmerzen|
|I’m allergic to||Ich bin allergisch gegen|
|I need a doctor who speaks English||Gibt es einen Arzt, der Englisch spricht?|
Additional information can be found in our Code of Conduct.
It is important to stay healthy and move around, especially when you are attending an event virtually. We have put together a few coffee break stretches and yoga videos in the conference platform for you to enjoy during the event.
Please use the Q&A function in the event platform.
If you have any other questions, you can go to the Help Desk in the event platform. Click on ‘more’ on the top menu and click Help Desk.
The programme is planned based on the Europe/Berlin time zone, unless otherwise stated. As many virtual participants are attending from around the world, we do our best to accommodate as many time zones as possible when creating the programme. Please take your time zone into consideration when planning your attendance. Remember to set your time zone in your account.
We are using a virtual event platform for this conference. More information about the platform will be shared ahead of the conference.
Please find additional information including FAQs, terms and conditions, COVID-19 safety policy and travelling to EMBL on our Information for Participants page.
We offer a variety of event sponsoring possibilities, with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget. Discounts are available for companies sponsoring multiple events at EMBL Heidelberg. View other conferences, or contact email@example.com for further information.
If you are interested in becoming a media partner of this event, please visit our media partnerships webpage.
EMBO | EMBL Symposia promote scientific communication and collaboration in the European research area. They provide scientists with a platform to discuss and exchange ideas on forward-looking topics and new developments in the life sciences.
Topics emphasise upcoming developments and the interdisciplinary nature of related fields. Jointly funded and organised by EMBO and EMBL – and complementary to their respective courses, workshops, and conference programmes – the symposia promote scientific communication and collaboration.
All symposia are held in the EMBL Advanced Training Centre (ATC) in Heidelberg, Germany, or virtually.