Defining and defeating metastasis

Symposium overview

This, the second edition of this symposium, will cover emerging key concepts of latent metastasis and dissemination of tumor cells including evolution and genetic diversity of metastasis, circulating tumor cells, stemness, dormancy and stromal reprogramming, transcriptional and epigenetic control, motility and invasive signaling, metastatic heterogeneity, EMT and plasticity, immune evasion and metabolic adaptations. The meeting will provide unique interdisciplinary exchange on current approaches and future collaborations on metastasis and its therapeutic challenges.

Metastasis research is a nexus for several of the most exciting areas and technical developments of current cancer biology and translational molecular medicine. High-resolution intravital imaging, single-cell sequencing and integrated genomics approaches, innovative tissue modelling and co-culture systems for disease screening and patient stratification all have enormous implications for our basic understanding of the mechanisms of this deadly disease, and hold great promises for progress in its successful treatment. This cutting-edge meeting is aimed at a broad spectrum of life scientists and clinicians working in cancer, immunology, cell and molecular biology.

What past participants say about the Symposium

“The ‘Defining and Defeating Metastasis’ Symposium was probably the best conference I have attended during my PhD. Engaging speakers, new science, and plenty of opportunity to network and socialise – all a stone’s throw from the centre of beautiful Heidelberg. Hoping for a repeat event in the future!” – Emma Colliver, Francis Crick Institute, UK

“As a PhD student in breast cancer research, the symposium in “Defining and defeating metastasis” was amazing. The speakers were excellent, and I left the conference with a lot of learning from established and new researchers. The EMBL Heidelberg venue was quiet and provided a good backdrop to discuss current research in metastasis. Catering was great, with many vegan/vegetarian options as well. The conference provided a lot of opportunities to network with other fellow students, but also with established researchers.” – Jomar, Gustave Roussy/Universite Paris-Saclay, France

“‘Defining and Defeating Metastasis’ was the most engaging and stimulating conference I ever attended. EMBL location is amazing and the conference was perfectly organised.” – Mila Gugnoni, Laboratory of Translational Research, AUSL-IRCCS Reggio Emilia, Italy

“The level of the science presented was great, did a marvellous work covering broad and key aspects of metastasis development.” – Beatriz Pérez, Garvan MRI, Australia (virtual participant)

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About

EMBO | EMBL Symposia promote scientific communication and collaboration in the European research area. They provide scientists with a platform to discuss and exchange ideas on forward-looking topics and new developments in the life sciences.

Topics emphasise upcoming developments and the interdisciplinary nature of related fields. Jointly funded and organised by EMBO and EMBL – and complementary to their respective courses, workshops, and conference programmes – the symposia promote scientific communication and collaboration.

All symposia are held in the EMBL Advanced Training Centre (ATC) in Heidelberg, Germany, or virtually.