Measuring translational dynamics by ribosome profiling – Course and Conference Office

EMBL Course

Measuring translational dynamics by ribosome profiling


Registration is not yet open for this event. If you are interested in receiving more information please register your interest.

Course overview

Regulation of translation is key in the control of gene expression, playing a critical role in many biological and pathophysiological settings. In the last decade, methodological advances have provided comprehensive insights into cellular transcriptomes and proteomes, however, the systems-wide analysis of translation remained an unsolved experimental challenge. The advent of ‘ribosome-profiling’ provided the methodological basis for comprehensive transcriptome-wide analyses of translation at sub-codon resolution by the precise and high-throughput determination of ribosomal positions on mRNA. Its application in a variety of organisms yielded novel insights into protein synthesis and its dynamic regulation, significantly advancing our understanding of the post-transcriptional regulation of gene expression.


The course is aimed at PhD students and early post-doctoral researchers who are entering the field of posttranscriptional regulation of gene expression.

Learning outcomes

The practical course ‘Measuring translational dynamics by ribosome profiling’ aims to:
a) generate a detailed theoretical understanding of ribosome profiling, its variations to address specific aspects of translation and its experimental strengths and limitations,
b) provide hands-on wet-lab training to perform ribosome-profiling experiments with the aim to understand and master the critical steps of the experimental workflow and to train the participants to independently perform and adapt similar experiments in their own laboratories,
c) provide hands-on bioinformatics training on processing the high-throughput sequencing data, the quality control and on the use of specialised tools for data generated by ribosome-profiling.

What past participants say about the course

The course gave a comprehensive understanding of ribosomal profiling from the theory and the scope of its impact, to practical work and analysing the data. It was a fantastic week filled with exciting discussions.” – Eleanor Bellows, University of Nottingham, UK

I leave the course much more confident of being able to perform my own Riboseq experiments in near future.” – Ashish Goyal, DKFZ Heidelberg, Germany

Please see EMBL’s COVID-19 safety recommendations for testing and other requirements to attend this on-site course.


Sponsorship opportunities

We offer a variety of event sponsoring possibilities, with the flexibility to select a set sponsorship package or combine individual sponsorship options to suit your event budget. Discounts are available for companies sponsoring multiple events at EMBL Heidelberg. View other events, or contact sponsorship@embl.de for further information.

If you are interested in becoming a media partner of this event, please visit our media partnerships webpage.


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Date: 23 - 28 Mar 2025

Location: EMBL Heidelberg

Venue: EMBL Advanced Training Centre


  • Pasha Baranov
    • Sebastian Leidel

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