
Genomic medicine: Ushering in a new era in healthcare
Perspectives, Science EMBL-EBI data resources are being used to deliver thousands of genetic diagnostics to patients every month.
2023
perspectivesscience
Perspectives, Science EMBL-EBI data resources are being used to deliver thousands of genetic diagnostics to patients every month.
2023
perspectivesscience
Science, Technology and innovation A new tool for the interpretation of missense variation in humans – ProtVar – will help enable drug discovery.
2023
sciencetechnology-and-innovation
Lab Matters, Research highlights Postdoctoral researcher Carolin Sauer is leveraging long-read sequencing to develop new detection methods for various cancers.
2023
lab-mattersresearch-highlights
Technology and innovation BioImage Archive Team Leader Matthew Hartley shares his experience and tips for people interested in managing a bioinformatics core facility.
2023
technology-and-innovation
EMBLetc Desmond Higgins, 2023 Lennart Philipson Award winner, discusses his time at EMBL and his research developing sequence alignment tools.
2023
Research highlights Understanding chromothripsis offers insights into how cancer develops.
2023
research-highlights
Announcements, Science The human pangenome – one of the most complete collections of genome sequences released so far – captures rich human diversity.
2023
announcementsscience
Announcements, Lab Matters EMBL-EBI is making a key contribution to a historic effort to understand the function of every human gene
2023
announcementslab-matters
Lab Matters, Perspectives On the 20th anniversary of the Human Genome Project, we look back at its history, wonder and potential.
2023
lab-mattersperspectives
Updates from data resources WormBase ParaSite release 18 adds largest number of new genomes and annotations since launch, as well as full integration with AlphaFold.
2023
updates-from-data-resources
Lab Matters, Perspectives Scientists have the technology to edit the human genome. But when should they, and who contributes to these decisions?
2023
lab-mattersperspectives
Research highlights, Science EMBL-EBI researchers have developed a new tool capable of performing state-of-the-art phylogenetic inference on larger datasets than previously thought possible.
2023
research-highlightsscience
Technology and innovation Darwin Tree of Life project improves bioinformatics tools for biodiversity data analysis
2023
technology-and-innovation
Science Using Oxford Nanopore long-read sequencing, EMBL scientists sequenced a primary childhood brain tumour known as a medulloblastoma, uncovering a novel complex mutation pattern.
2023
science
Perspectives Using long-read sequencing and machine learning approaches, EMBL alumna Lara Urban is making a difference in the field of One Health.
2023
perspectives
Research highlights, Science EMBL-EBI researchers use UK Biobank data to uncover new information about rare diseases of the eye.
2023
research-highlightsscience
Perspectives, Science As major biodiversity projects ramp up, EMBL-EBI enables genomic data sharing for all species.
2023
perspectivesscience
Updates from data resources EMBL-EBI’s Software Development and Operations team is delighted to announce the launch of a brand-new Job Dispatcher website, currently in development. The updated website provides a landing page for the Job Dispatcher services, making it easier for users to find and navigate services…
2023
updates-from-data-resources
Lab Matters, Perspectives Jo McEntyre talks about data services, open data and a new era for research assessment.
2023
lab-mattersperspectives
Lab Matters Group Leader Hanh Vu studies ‘immortal’ flatworms that can grow and de-grow to understand better factors that determine organisms’ sizes.
2023
lab-matters
Updates from data resources Latest Ensembl and Ensembl Genomes releases bring updates to donkey and horse assemblies, and lots of new plants and metazoa.
2023
updates-from-data-resources
Perspectives, Science Genomic sequencing and big data analysis are two novel technologies driving researchers’ understanding of the complexities of cancer.
2023
perspectivesscience
Science, Technology and innovation Open Targets is using artificial intelligence and machine learning to identify and prioritise drug targets.
2023
sciencetechnology-and-innovation
Perspectives, Science We look back through some of the 2022 highlights from the Darwin Tree of Life project.
2023
perspectivesscience
Lab Matters Rob Finn, one of the co-chairs of the Microbial Ecosystems theme, discusses his work, the challenges of multidisciplinary research, and how the theme is already helping to promote the exchange of scientific ideas.
2023
lab-matters
Research highlights, Science A new method developed by EMBL-EBI researchers helps to streamline nanopore sequencing in real-time.
2023
research-highlightsscience
Announcements, Science EMBL-EBI supports new European Commission project set to support the use of genomics in research and healthcare.
2022
announcementsscience
Announcements An ambitious project to sequence the genomes of all known species of euglenoids will drive research on biofuels and sustainable foods.
2022
announcements
Announcements, Science Open Targets announces that Genentech will become the seventh partner in the drug discovery and validation consortium.
2022
announcementsscience
Perspectives, Science Our experts discuss the importance of open science for food security and preserving global biodiversity.
2022
perspectivesscience
Research highlights, Science Researchers have created a tool that maps in previously unseen detail how breast cancer develops and spreads.
2022
research-highlightsscience
Updates from data resources We are pleased to announce the release of Ensembl 108, and the corresponding release of Ensembl Genomes 55 featuring changes in the human default tracks, new genomes in Ensembl Plants and Ensembl Metazoa, and the addition of mitochondrial annotation for Tasmanian devil. Genome assemblies and…
2022
updates-from-data-resources
Updates from data resources Data continues to be available in BioStudies.
2022
updates-from-data-resources
Announcements, Science European experts gather to launch a project that aims to characterise and conserve life on Earth using DNA data.
2022
announcementsscience
Announcements, Science The Federated EGA is set to improve access to sensitive human data in a safe and secure way.
2022
announcementsscience
Lab Matters Dieter Schwarz Foundation renews 3-year funding to EMBL for the EMBL | Stanford Life Science Alliance, a unique international collaboration bringing together researchers from the two leading institutions to develop transformative technologies and accelerate biomedical research.
2022
lab-matters
Research highlights, Science A new method for the robust analysis of copy number variation and used UK Biobank data to identify links between genome and disease.
2022
research-highlightsscience
Research highlights, Science International consortium analyses the genetic sequences and antibiotic susceptibility of 10,000 global Mycobacterium tuberculosis isolates.
2022
research-highlightsscience
Research highlights, Science Scientists identify previously unexplored gene segments to be added to human genome databases.
2022
research-highlightsscience
Updates from data resources The Ensembl 107 release contains updates to regulatory annotations and updated vertebrate and metazoan species.
2022
updates-from-data-resources
Updates from data resources Using powerful data visualisation and interactive search results across datasets allows users to explore hypotheses across a range of metadata, and discover new insights backed by expertly curated, consistently reanalysed single cell sequencing data. Searching for metadata, allows a powerful…
2022
updates-from-data-resources
Announcements A closer look at how genome sequencing is helping us protect biodiversity and our latest public engagement activities
2022
announcements
Announcements, Lab Matters The African BioGenome Project and EMBL have signed a Memorandum of Understanding to support each other in building genomics and bioinformatics capacity across Africa
2022
announcementslab-matters
Research highlights, Science Researchers discover how DNA mutations change blood cell production and how this relates to ageing and cancer development.
2022
research-highlightsscience
Science, Technology and innovation Researchers in the Ensembl team are making the most of machine learning methods to speed up genome annotation pipelines
2022
sciencetechnology-and-innovation
Lab Matters Fergal Martin discusses the importance of open access data and his work in different biodiversity initiatives
2022
lab-matters
Lab Matters, Perspectives Janet Thornton, the inaugural winner of the FEBS Journal Open Science Award, explains the importance and impact of open science.
2022
lab-mattersperspectives
Lab Matters Peter Harrison discusses the importance of data accessibility and his passion for biodiversity and agricultural genomics.
2022
lab-matters
Lab Matters, Perspectives Ewan Birney discusses the input of both genetics and our environment in making us who we are
2022
lab-mattersperspectives
Research highlights, Science Researchers from the MANE collaboration bring you the most comprehensive human genome annotation dataset to date.
2022
research-highlightsscience
Lab Matters John Lees joins EMBL-EBI as a Group Leader in Pathogen informatics and modelling.
2022
lab-matters
Perspectives Researchers lay out a set of principles for open genomic data sharing or pathogens
2022
perspectives
Perspectives, Science Zamin Iqbal and his team are working with researchers all over the globe to help put a stop to Tuberculosis
2022
perspectivesscience
Announcements, Science Scientists urge the adoption of a sensible international policy for digital sequence information.
2022
announcementsscience
Announcements, Science Open Targets, a consortium focused on drug target identification, prioritisation, and validation, announced today that Pfizer has joined as a partner.
2022
announcementsscience
Perspectives, Science An exploration of where in the world genomics methods are applied and where the data are used.
2022
perspectivesscience
Science How genomics, open data, and multidisciplinary science can improve food security.
2021
science
Science The Darwin Tree of Life project is an unprecedented initiative sequencing 70,000 species
2021
science
Science Largest in-depth analysis of genomic data tracks the spread of SARS-CoV-2 lineages in England.
2021
science
Science A research collaboration used machine learning to map tumour molecular make-up, potentially paving way to more customised cancer treatment.
2021
science
Science A new collaborative study led by EMBL group leaders Kiran Patil, Nassos Typas, and Peer Bork has found that common medications accumulate in human gut bacteria. This process reduces drug effectiveness and affects the metabolism of common gut microbes, thereby altering the gut microbiome.
2021
science
Lab Matters EMBL welcomes Sarah Dyer, the new Non-Vertebrate Genomics Team Leader at EMBL-EBI.
2021
lab-matters
Lab Matters EMBL and the Swedish Science for Life Laboratory sign agreement to advance science together.
2021
lab-matters
Science The largest in-depth analysis of genomic surveillance data mapping out the dynamics of 62 lineages of the SARS-CoV-2 virus.
2021
science
Science Researchers reveal the best technology for assembling reference genomes.
2021
science
Science The Gerstung Group at EMBL-EBI and collaborators have developed a statistical model that analyses genomic data to predict whether a patient has a high or low risk of developing oesophageal cancer.
2020
science
Science An international team of scientists involving Ewan Birney's group has investigated the function of a complex mesh of muscle fibres that line the inner surface of the heart.
2020
science
Science A global team of researchers including the Flicek Team at EMBL-EBI has partnered up with the Māori tribe Ngātiwai to sequence the genome of the tuatara, a rare reptile endemic to New Zealand.
2020
science
Science An international team of scientists has collated all known bacterial genomes from the human gut microbiome into a single large database. Their work will allow researchers to explore the links between bacterial genes and proteins, and their effects on human health.
2020
science
Lab Matters This year, EMBO elected 63 new members, including Alexander Aulehla, Group Leader and Senior Scientist at EMBL Heidelberg, and Paul Flicek, Associate Director of EMBL-EBI Services, Senior Scientist, Group and Team Leader at EMBL-EBI.
2020
lab-matters
Lab Matters Open Targets welcomes new Informatics Science Director
2020
lab-matters
Science Today we celebrate the 20th anniversary of the first draft of the entire human genome.
2020
science
Science DNA damage caused by chemical mutagens is not repaired immediately and can create more genetic diversity in tumours.
2020
science
Science EMBL scientists have performed a large-scale analysis of over 4700 SARS-CoV-2 genome sequences. They found that many of the most interesting changes in the SARS-CoV-2 genome that have been reported so far are likely to be technical artefacts, rather than biological mutations.
2020
science
Science EMBL scientists will contribute to the new German COVID-19 OMICS Initiative to study the biological mechanisms contributing to coronavirus infections. EMBL group leaders Jan Korbel and Oliver Stegle, who is also affiliated with the DKFZ Heidelberg, will coordinate the set-up of IT infrastructures…
2020
science
Science DNA mutations are caused by a combination of DNA damage and repair, shows study by EMBL-EBI and collaborators.
2020
science
Science Exploring the cancer genomics labyrinth
2019
science
Science Understanding how ageing works at a molecular level
2019
science
Science The increasing importance of code in the biological sciences
2019
science
Science Using genomics to help endangered species
2019
science
Lab Matters Building bonds between academia and industry
2019
lab-matters
Lab Matters Enhancing the world's bioinformatics infrastructure
2019
lab-matters
Science Federated data sharing will now be possible on an unprecedented scale
2019
science
Lab Matters How EMBL scientists are using machine learning to advance biology
2018
lab-matters
Lab Matters Pharmaceutical company Sanofi strengthens drug targets discovery collaboration Open Targets
2018
lab-matters
Science How embryonic stem cells develop into the germ line
2018
science
Events Meet the organisers of EMBO’s first course on molecular geobiology
2018
events
Science Acute myloid leukaemia risk could be detected years before diagnosis
2018
science
Science What worms can tell us about cancer
2018
science
Science Is depression in your genes?
2018
science
Science EMBL scientists unveil how 3D chromatin structure affects RNA splicing
2017
science
Science A summary of recent research highlights from EMBL
2017
science
Events EMBL-EBI and collaborators engage schools in a large-scale genome decoding project
2017
events
Science Genetic data from a major cohort now distributed via EMBL-EBI
2017
science
Science ERC grantee Eileen Furlong shares her vision for the next ten years
2017
science
Alumni EMBL alumna Nicola Mulder reflects on her pan-African bioinformatics project and its impact
2017
alumni
Science EMBL scientists discovered that common mutations can change the shape of gene promoters
2017
science
Science New mechanism revealed
2017
science
Science Where design meets bioinformatics, new scientific perspectives abound.
2016
science
Science “Like getting hold of a microscope for the first time”
2016
science
Science Collaborations shorten distance between EMBL Heidelberg, Germany, and CEITEC in Brno, Czech Republic
2016
science
Science What's a microbiome? How on Earth do they work?
2016
science
Science From shared interests at a conference to a surprising discovery
2016
science
Science Largest-ever study of breast cancer genomes reveals new genes and mutations
2016
science
Science Subtle genetic differences destine cells to placenta or animal, very early in embryo development
2016
science
Science TraCeR: new method for studying T cells opens up opportunities to explore immune responses
2016
science
Science First detailed atlas of start points for genes expression in malaria-causing parasite
2016
science
Science Commonly used diabetes drug metformin impacts gut bacteria more than disease itself
2015
science
Events Connecting entrepreneurs and world leaders in genomics to address opportunities and challenges.
2015
events
Science From jumping genes to organ transplants, the non-human features that make us human.
2015
science
Lab Matters EMBL scientists regularly receive prestigious awards – meet the latest honourees.
2015
lab-matters
Science Embryology, genomics and bioinformatics combine to identify factors regulating mammalian pluripotency.
2015
science
Science Evaluation of MinION™ sequencer finds performance and reliability consistently good.
2015
science
Science Study of mouse embryonic stem cells reveals new genes involved in the stem-cell regulatory network.
2015
science
Science 1000 Genomes Project pushed technologies and knowledge forward to understand what is 'normal' human genetic variation
2015
science
Science From the role of diatoms to how life evolved - scientists' pressing questions about life in the sea.
2015
science
Science Missing a gene may not be a big deal – a conclusion from global catalogue of genetic changes.
2015
science
Events Insights from organisers of upcoming EMBO|EMBL Aquatic Microeukaryotes symposium.
2015
events
Science Multifaceted approach reveals how brain and liver age, helps explain why ageing brain loses plasticity.
2015
science
Lab Matters EMBL scientists regularly receive prestigious awards – meet the latest honourees.
2015
lab-matters
Alumni Behind the scenes of start-up Miroculus, developing a non-invasive test for early-stage disease.
2015
alumni
Science A journalist who spent six weeks aboard Tara reflects on the expedition’s extraordinary outcomes.
2015
science
Lab Matters EMBL Core Facilities collaborate with French research programme Signalife to revive training visit.
2015
lab-matters
Events Leading scientists will gather in Heidelberg this November to discuss the potential of personalised health.
2015
events
Science Multidisciplinary research provides clues to new treatments for deadly form of leukaemia in children
2015
science
Science How T-cells are trained on what not to kill
2015
science
Science European team identify mechanism for producing piRNAs that silence jumping genes in germline cells.
2015
science
Science Decaying RNA molecules tell a story that could add more chapters to the study of ribosomes.
2015
science
Science New research shows that some proteins domains can function even with big parts missing.
2015
science
Science Cooperate or compete? Microbes show us that getting along is the better choice for communities.
2015
science
Alumni Career insights from Riccardo Cortese, whose start-up is developing an Ebola vaccine candidate.
2015
alumni
Science Radiocarbon studies are helping researchers shine light on how neurons stay stable yet adaptable.
2015
science
Alumni Exploring the science and magic of Lil Bub – alumna launches project to sequence the ‘Lilbubome’.
2015
alumni
Science New single-cell genomics techniques bring ‘omics to evolution and development research.
2015
science
Science Go Team Genome! New method reveals genetic teamwork in drosophila genome.
2015
science
Science How repurposing non-coding elements in the genome gave rise to the great ‘mammalian radiation’.
2015
science
Lab Matters EMBL scientists regularly receive prestigious awards – meet the latest honourees.
2015
lab-matters
Lab Matters New Christian Boulin Fellowship: 15 awards of up to €1500 for visitors to EMBL’s Core Facilities.
2015
lab-matters
Alumni Announcing winners of the John Kendrew Young Scientist Award, and inaugural Lennart Philipson Award.
2014
alumni
Lab Matters Third round of calls for joint research projects between EMBL and Luxembourg in 2015
2014
lab-matters
Science Largest collection of helminth genomic data ever assembled, in new open-access WormBase ParaSite.
2014
science
Science The important thing is forming good biological questions, says new group leader in Genome Biology.
2014
science
Science Whether it’s information or people, the art of connecting is key to new group leader Judith Zaugg
2014
science
Events First series of training courses jointly organised by EMBL and Illumina is a resounding success.
2014
events
Events Experts from multiple fields come together to understand how the instructions in genes are read
2014
events
Events EMBL-EBI hosts successful first EMBO Practical Course in Genotype to Phenotype Mapping.
2014
events
Science Gibbon genome gives insights into evolution of this singing, swinging, tree-dwelling ape.
2014
science
Science Bronwen Aken discusses what research into the rabbit genome reveals about animal domestication.
2014
science
Events PhD students reap rewards and rave reviews as Summer School of Science organisers
2014
events
Science Ensembl has incorporated a vast amount of knowledge into a fully annotated reference human genome
2014
science
Lab Matters New genomics API allows researchers to share anonymised genetic data seamlessly across platforms.
2014
lab-matters
Science Marmoset genome provides insights into chimerism: data available in Ensembl genome explorer
2014
science
Lab Matters School ambassadors show next generation that scientists are more ‘role model’ than ‘mad professor’
2014
lab-matters
Lab Matters Scientists from EMBL's five sites reflect on the opportunities and challenges that might lie ahead
2014
lab-matters
Science Enabling neighbours: intact genes can cause cancer when placed near "enhancing" regions of DNA
2014
science
Science Data from first ever worldwide Ocean Sampling Day will be shared via EMBL-EBI resources this autumn.
2014
science
Science Reference sheep genome, published by International Sheep Genomics Consortium, available in Ensembl
2014
science
Science Tsetse fly genome sequenced; scientists hope to find new ways to control sleeping sickness.
2014
science
Science In 1870 the German scientist Ernst Haeckel mapped the evolutionary relationships of plants and animals in the first ‘tree of life’. Since then scientists have continuously redrawn and expanded the tree adding microorganisms and using modern molecular data, yet, many parts of the tree…
2006
science
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