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Genomics

The tuatara, an iguana-like reptile with a crest of spikes, sits on a forest floor.

The curious genome of the tuatara, an ancient reptile in peril

A global team of researchers including the Flicek Team at EMBL-EBI has partnered up with the Māori tribe Ngātiwai to sequence the genome of the tuatara, a rare reptile endemic to New Zealand.

By Mehdi Khadraoui

Science

A magnifying glass hovers over the human gut, revealing its biodiversity.

Unparalleled inventory of the human gut ecosystem

An international team of scientists has collated all known bacterial genomes from the human gut microbiome into a single large database. Their work will allow researchers to explore the links between bacterial genes and proteins, and their effects on human health.

By Mehdi Khadraoui

Science

Alexander Aulehla on the left and Paul Flicek on the Right

Two EMBL scientists become EMBO Members

This year, EMBO elected 63 new members, including Alexander Aulehla, Group Leader and Senior Scientist at EMBL Heidelberg, and Paul Flicek, Associate Director of EMBL-EBI Services, Senior Scientist, Group and Team Leader at EMBL-EBI.

By Mehdi Khadraoui

Lab Matters

New Informatics Science Director at Open Targets, Ellie McDonagh

Welcome: Ellie McDonagh

Open Targets welcomes new Informatics Science Director

By Mehdi Khadraoui

Lab Matters

Five things you probably didn't know about the Human Genome Project

Five things you probably didn’t know about the Human Genome Project

Today we celebrate the 20th anniversary of the first draft of the entire human genome.

By Mehdi Khadraoui

Science

Artist's impression of DNA lesions. Credit: Petra Korlevic

Unpicking the complexity of DNA mutations

DNA damage caused by chemical mutagens is not repaired immediately and can create more genetic diversity in tumours.

By Oana Stroe

Science

Bioinformatic analysis of over 4700 SARS-CoV-2 genomes revealed that many of the most interesting changes in the SARS-CoV-2 genome that have been reported so far are likely to be technical artefacts, rather than biological mutations.

Distinguishing coronavirus genome mutations from inadvertent errors

EMBL scientists have performed a large-scale analysis of over 4700 SARS-CoV-2 genome sequences. They found that many of the most interesting changes in the SARS-CoV-2 genome that have been reported so far are likely to be technical artefacts, rather than biological mutations.

By Marius Bruer

Science

Close-up photograph of servers at EMBL Heidelberg's data centre.

Understanding the role of our genes in SARS-CoV-2 infections

EMBL scientists will contribute to the new German COVID-19 OMICS Initiative to study the biological mechanisms contributing to coronavirus infections. EMBL group leaders Jan Korbel and Oliver Stegle, who is also affiliated with the DKFZ Heidelberg, will coordinate the set-up of IT infrastructures…

By Marius Bruer

Science

DNA damage and repair jointly leave mutational signatures in the genome.

DNA damage and faulty repair jointly cause mutations

DNA mutations are caused by a combination of DNA damage and repair, shows study by EMBL-EBI and collaborators.

By Mehdi Khadraoui

Science

Isidro Cortes-Ciriano

Welcome: Isidro Cortés-Ciriano

Exploring the cancer genomics labyrinth

By Oana Stroe

Science

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