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cell biology

Year
21 January 2022 The cross-section of a cell expressing a green fluorescently tagged protein and illuminated by a blue laser is visible in the foreground, surrounded by a vortex of cells

Cell sorting enters a new dimension

Science EMBL researchers, in collaboration with BD Biosciences, have demonstrated a new technology that allows rapid image-based sorting of cells. The new technology represents a major upgrade to flow cytometry and has applications in diverse life science fields.

2022

science

9 December 2021 Colourful interwoven coils are displayed against a grid of small black and white photographic images.

A gallery of human RNA polymerases

Science New structural biology research provides fundamental information critical to understanding enzyme mutations connected to rare diseases and cancers.

2021

science

29 November 2021 Male scientist in front of blurred woodland background

Welcome: Niccolò Banterle

Lab Matters Using gene editing and three types of microscopy, one of EMBL’s newest group leaders is deciphering the functions of one of the smallest molecules involved in cell division, motility, and signalling, known as a centriole.

2021

lab-matters

22 October 2021 Oblong shape with two holes and coloured dots inside, representing phytoplankton cells and nitrogen-fixing bacteria

Analysis and sorting with flow cytometry

Lab Matters A technology around since the ‘60s, flow cytometry has increasing applications. New leadership at EMBL’s flow cytometry facilities is looking to ease use, expand training, and encourage more collaboration.

2021

lab-matters

5 October 2021 Illustration of a globe with colourful shapes and symbols superimposed.

A cellular atlas of an entire worm

Science EMBL scientists and colleagues have developed an interactive atlas of the entire marine worm Platynereis dumerilii in its larval stage. The PlatyBrowser resource combines high-resolution gene expression data with volume electron microscopy images.

2021

science

22 June 2021 Woman stands at brown railing in front of trees

Welcome: Anna Erzberger

Lab Matters Anna Erzberger, one of EMBL’s newest group leaders, will provide unique perspective as a theoretical biological physicist.

2021

lab-matters

1 June 2021 Two purple and white spheres against dark background.

Nuclear twins

Picture of the week Captured by EMBL postdoc Arina Rybina, these ‘nuclear twins’ are two daughter nuclei straight after division of a HeLa cell.

2021

picture-of-the-week

27 April 2021 Microscope image of liver cells, highlighted in various colours.

Painting liver cells

Picture of the week A page from a biologist’s colouring book? EMBL’s new interior wall design? Not quite – a bunch of liver cells, grown in the lab so that scientists can learn about fatty liver disease, or steatosis.

2021

picture-of-the-week

2 December 2020 The image is a green coloured cell, with a wild and textured surface which is composed of many different shapes and shadows.

Scratching the surface on cell differentiation

Science Scientists in the Diz-Muñoz group at EMBL Heidelberg are working to build understanding of the role that mechanical properties play in affecting cell behaviour – a young and rapidly developing field of study. They have developed and successfully used a highly specialised technique to manipulate…

2020

science

27 October 2020 Microscopic image of a cell, nucleus visible in bright green, cell membrane stained with a purple dye against black background.

Party at the nucleus?

Picture of the week The nucleus of this cell fluoresces in bright green thanks to GFP-labelled nucleoporin proteins. EMBL scientists use engineered nucleoporins as 3D reference standards to improve super-resolution microscopy.

2020

picture-of-the-week

18 September 2020 Composite image of mouse cells and human cells showing different levels of luminescence, indicated as different colours.

Human and mouse cells run at different speeds

Science The internal clock that governs the development of embryos ticks slower for humans than for mice. Differences in the speed of biochemical reactions underlie the differences between species in the tempo of development.

2020

science

21 July 2020 Top row: The evolution of tumour cells (green) within a normal organoid (grey) shown in three panels. Lower row: Surface rendition of tumour cells and labels new cells that arise from a single cell in the same colour.

A tool to improve cancer research

Science EMBL scientists have created a new, realistic 3D testbed that could help achieve the goal of stopping cancers before they start by studying cancer cells as they first form.

2020

science

9 July 2018 Miki Ebisuya at EMBL Barcelona

Welcome: Miki Ebisuya

Science New group leader at EMBL Barcelona creates artificial biological systems to study animal development

2018

science

8 January 2018 A photo of new EMBL Heidelberg group leader Aissam Ikmi.

Welcome: Aissam Ikmi

Science New group leader studies sea anemones to investigate why some animals regenerate better than others

2018

science

23 November 2017 Floating approximately 400 km above the Earth, the International Space Station provides a platform for scientific research in space.

Science in space

Alumni EMBL alumna Sigrid Reinsch trained as a cell biologist – now she helps run experiments in space

2017

alumni

11 August 2017

Welcome: Justin Crocker

Science Meet Justin Crocker, EMBL’s new group leader in gene regulation during evolution and development

2017

science

23 February 2017

Building labs with flies

Alumni Flies can do a lot for science, inside and outside the lab. EMBL alumna Isabel Palacios explains how

2017

alumni

7 December 2016

Cycle of life

Science Paul Nurse’s failed experiment inspired a career that would uncover key mechanisms of cell division

2016

science

1 December 2016

Design for life

Lab Matters EMBL’s Petra Riedinger retires after 40 years producing posters, graphics, artwork and more

2016

lab-matters

24 November 2016

Chromatin cartographer

Alumni EMBL alumnus Jop Kind reflects on the questions that led him to this year’s John Kendrew Award

2016

alumni

21 April 2016 EMBL scientists are discovering and understanding the waves and rhythms inside us. ILLUSTRATION: Aad Goudappel, Rotterdam

The rhythms in life

Science How EMBL scientists are discovering and understanding the waves and rhythms inside us

2016

science

21 March 2016 First complete, real-time recording of starfish egg cell eliminating centrioles shows it handles mature ‘mother’ centrioles (green) and immature ‘daughter’ centrioles (purple) differently.

Mothers and daughters

Science 1st real-time video of starfish egg cell eliminating crucial structures, to ensure embryo viability

2016

science

17 December 2015 Digital zebrafish embryo provided the first complete developmental blueprint of a vertebrate in 2008. IMAGE: EMBL/Keller et al.

SPIM doctors

Science From initial development to a start-up company: Selective Plane Illumination Microscopy (SPIM) at EMBL.

2015

science

30 October 2015

One hard pull

Science Fibres that pull membrane to form a vesicle exert a force that’s 2500 times a yeast cell’s own weight

2015

science

24 August 2015

Cellular synergy

Events Alumnus Thomas Vaccari reflects on the first joint symposium with EMBL Monterotondo, in Milan.

2015

events

21 May 2015

Sense of space

Science EMBL scientists demonstrate that spatial constraints are a key factor in determining nucleus size.

2015

science

16 March 2015

No humans required

Science New fully automated technique enables scientists to chart complex protein networks in living cells.

2015

science

4 March 2015 Where and when are different molecules contributing to the bending of the membrane? IMAGE: EMBL/A. Picco

Best of three worlds

Science Combining three different kinds of microscopy to determine how molecules move during endocytosis.

2015

science

25 February 2015 The team used computer simulations to investigate the mitotic spindle's strength. IMAGE: EMBL/F. NÉDÉLEC

Under pressure

Science How strong does a spindle need to be? Videos put cell’s chromosome-separating machinery to the test

2015

science

4 February 2015 The new method helps identify which mutations to a gene actually cause a disease. IMAGE FROM THORMAEHLEN ET AL.

Beyond sequencing

Science New microscopy-based method goes beyond gene sequencing, pinpointing the cause of disease.

2015

science

26 January 2015

Awards & Honours

Lab Matters EMBL scientists regularly receive prestigious awards – meet the latest honourees.

2015

lab-matters

11 November 2014

Polish connections

Alumni Alumna Anna Bartosik shares insights and hopes for EMBL's newest prospect member state, Poland.

2014

alumni

23 October 2014

Chamber of secrets

Science Like sports teams, cells can huddle to communicate in secret and organise group behaviour

2014

science

20 October 2014

Breaking boundaries

Science How Nobel-winning work by alumnus Stefan Hell shapes and inspires current EMBL scientists' research.

2014

science

21 August 2014

Drawing on nature

Events PhD Symposium poster reveals how a cell’s inner workings serve as both inspiration and toolkit.

2014

events

20 August 2014

Binding bracelet

Science Vasa protein preserves pieces of 'enemy' DNA to help protect the genes of future generations.

2014

science

1 April 2010 Each of these large images of dividing cells is composed of several microscopy images of human cells in which different individual genes were silenced. The smaller images are placed according to genes’ effects: images for genes that affect chromosomes make up the chromosomes (red/pink), while the mitotic spindle (green) is composed of images for genes that affect it. IMAGE: Thomas Walter & Mayumi Isokane / EMBL

Movies for the human genome

Science Name a human gene, and you’ll find a movie online showing you what happens to cells when it is switched off. This is the resource that researchers at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, and their collaborators in the Mitocheck consortium are making freely…

2010

science

4 March 2007

A clearer view on biology

Science The European Molecular Biology Laboratory (EMBL) has developed a new computational tool that makes images obtained with cutting-edge microscopes even sharper. The technological advance and its applications are published in this week’s online issue of the journal Nature Methods. Since the…

2007

science

27 September 2006

How nature tinkers with the cellular clock

Science The life of a cell is all about growing and dividing at the right time. That is why the cell cycle is one of the most tightly regulated cellular processes. A control system with several layers adjusts when key components of the cell cycle machinery are produced, activated and degraded to make sure…

2006

science

3 February 2005

Biology in four dimensions

Science Most things that happen in the cell are the work of ‘molecular machines’ – complexes of proteins that carry out important cellular functions. Until now, scientists didn’t have a clear idea of when proteins form these machines – are these complexes pre-fabricated or put…

2005

science

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