Spotlight: A giant in action
Lab Matters, Picture of the week Physarum polycephalum, a single, giant cell containing tens of thousands of nuclei is large enough to be photographed with a phone.
2022
lab-matterspicture-of-the-week
Cell sorting enters a new dimension
Science EMBL researchers, in collaboration with BD Biosciences, have demonstrated a new technology that allows rapid image-based sorting of cells. The new technology represents a major upgrade to flow cytometry and has applications in diverse life science fields.
2022
science
A gallery of human RNA polymerases
Science New structural biology research provides fundamental information critical to understanding enzyme mutations connected to rare diseases and cancers.
2021
science
Welcome: Niccolò Banterle
Lab Matters Using gene editing and three types of microscopy, one of EMBL’s newest group leaders is deciphering the functions of one of the smallest molecules involved in cell division, motility, and signalling, known as a centriole.
2021
lab-matters
Analysis and sorting with flow cytometry
Lab Matters A technology around since the ‘60s, flow cytometry has increasing applications. New leadership at EMBL’s flow cytometry facilities is looking to ease use, expand training, and encourage more collaboration.
2021
lab-matters
When ‘good’ cells go ‘bad’
Science If researchers can identify specifically when good cells go bad, they can potentially understand disease better.
2021
science
A cellular atlas of an entire worm
Science EMBL scientists and colleagues have developed an interactive atlas of the entire marine worm Platynereis dumerilii in its larval stage. The PlatyBrowser resource combines high-resolution gene expression data with volume electron microscopy images.
2021
science
Cryo-Electron Microscopy Service Platform supports research on protein transport
Lab Matters Giulia Zanetti from the Institute of Structural and Molecular Biology (ISMB) in London explains how the collaboration with the Cryo-Electron Microscopy Service Platform enabled her group to reveal the structure of protein transport complexes.
2021
lab-matters
Welcome: Anna Erzberger
Lab Matters Anna Erzberger, one of EMBL’s newest group leaders, will provide unique perspective as a theoretical biological physicist.
2021
lab-matters
Nuclear twins
Picture of the week Captured by EMBL postdoc Arina Rybina, these ‘nuclear twins’ are two daughter nuclei straight after division of a HeLa cell.
2021
picture-of-the-week
SARS-CoV-2 curtails immune response in the gut
Science EMBL scientists, together with collaborators from Heidelberg University, have provided further evidence of the gut’s role in COVID-19.
2021
science
Painting liver cells
Picture of the week A page from a biologist’s colouring book? EMBL’s new interior wall design? Not quite – a bunch of liver cells, grown in the lab so that scientists can learn about fatty liver disease, or steatosis.
2021
picture-of-the-week
At the core of the Integrator complex
Science A new paper from the Galej group at EMBL Grenoble describes the structure of key parts of the Integrator complex, involved in gene expression.
2021
science
EMBL group leader Miki Ebisuya receives ERC Consolidator Grant
Lab Matters Funding by the European Research Council (ERC) will support research on the timing of developmental processes in mammals
2020
lab-matters
Scratching the surface on cell differentiation
Science Scientists in the Diz-Muñoz group at EMBL Heidelberg are working to build understanding of the role that mechanical properties play in affecting cell behaviour – a young and rapidly developing field of study. They have developed and successfully used a highly specialised technique to manipulate…
2020
science
Party at the nucleus?
Picture of the week The nucleus of this cell fluoresces in bright green thanks to GFP-labelled nucleoporin proteins. EMBL scientists use engineered nucleoporins as 3D reference standards to improve super-resolution microscopy.
2020
picture-of-the-week
Human and mouse cells run at different speeds
Science The internal clock that governs the development of embryos ticks slower for humans than for mice. Differences in the speed of biochemical reactions underlie the differences between species in the tempo of development.
2020
science
A tool to improve cancer research
Science EMBL scientists have created a new, realistic 3D testbed that could help achieve the goal of stopping cancers before they start by studying cancer cells as they first form.
2020
science
Taking a closer look at infected cells to better understand COVID-19
Science EMBL electron microscopy specialists collaborate with researchers from Heidelberg University Hospital to understand the changes occurring in cell structures upon SARS-CoV-2 infection.
2020
science
Machine learning finds critical phosphosites
Science Resource has implications for disease research
2019
science
Photo-micropatterning advances structural cell biology
Science A new technique in cryo-EM
2019
science
ATP affects proteome-wide solubility
Science Scientists develop technology to measure how ATP concentration affects protein solubility in cells
2019
science
Understanding early embryo development in mice
Science How organs form in a mouse embryo
2019
science
EMBL in the UK: Wendy Bickmore
Alumni Meet Wendy Bickmore, Director of the MRC Human Genetics Unit, who spoke at the EMBL in the UK event
2018
alumni
EMBL in Finland: Marja Makarow
Alumni Scientists in Finland met to share ideas and discover research opportunities
2018
alumni
The proteins behind hungry cells
Science EMBL researchers visualise the proteins needed to capture molecules and bring them into a cell
2018
science
Welcome: Miki Ebisuya
Science New group leader at EMBL Barcelona creates artificial biological systems to study animal development
2018
science
EMBL in Italy: Kristina Havas-Cavalletti
Alumni More than 80 attendees gathered at the EMBL in Italy event at the FIRC Institute of Molecular Oncology (IFOM) in Milan
2018
alumni
Melina Schuh receives EMBO Gold Medal
Alumni EMBL alumna Melina Schuh recognised for excellence in science
2018
alumni
New software makes 3D imaging accessible
Science Open-source software allows standard microscopes to accurately image 3D structures
2018
science
Counting condensins on chromosomes
Science EMBL scientists count and locate chromosomal proteins during cell duplication
2018
science
From blood vessels to blood stem cells
Science EMBL scientists discover how blood vessel cells become blood stem cells during embryonic development
2018
science
DNA replication stress in cancer
Events Thanos Halazonetis discusses the EMBO/EMBL Symposium: DNA Replication: From Basic Biology to Disease
2018
events
Welcome: Sara Cuylen-Häring
Science New EMBL group leader explores biophysical properties of chromosomes and other cellular assemblies
2018
science
Welcome: Aissam Ikmi
Science New group leader studies sea anemones to investigate why some animals regenerate better than others
2018
science
Chromosomes don’t need key protein for all their folds
Science New research reveals that two different mechanisms are responsible for chromosome folding
2017
science
Cells grow pores from shrinking holes
Science New research shows how pores form in the membrane that surrounds a cell’s nucleus
2017
science
Science in space
Alumni EMBL alumna Sigrid Reinsch trained as a cell biologist – now she helps run experiments in space
2017
alumni
Research highlights
Science A summary of recent research highlights from EMBL
2017
science
Looping the loops: how chromosomes form
Science EMBL researchers and collaborators unravel how chromosomes form
2017
science
Welcome: Justin Crocker
Science Meet Justin Crocker, EMBL’s new group leader in gene regulation during evolution and development
2017
science
40 years of electron microscopy training at EMBL
Events Celebrating 40 years since the first EMBO electron microscopy training course
2017
events
Open imaging data for biology
Science The Image Data Resource - prototype of the first open repository linking imaging and molecular data
2017
science
Mapping gene expression, cell by cell
Science EMBL researchers complete a molecular atlas showing gene expression in all cells in an entire animal
2017
science
Senses: Silencing noise
Science Two EMBL researchers are exploring new ways to filter out noise and get to the data they need
2017
science
Cell changes drive breast cancer relapse
Science Hallmarks of residual breat cancer cells suggest new approaches for preventing relapse
2017
science
Futures: Phosphatases
Science ERC grantee Maja Köhn shares her vision for the next ten years
2017
science
Illuminating insulin release
Science EMBL researchers develop an optical method for measuring the release of insulin from single cells
2017
science
Structure of key system for TB infection
Science EMBL scientists add crucial knowledge to understanding of the bacterium that causes tuberculosis
2017
science
Blood stem cell differentiation is continuous
Science Study by EMBL and DKFZ researchers means origins of myeloid leukaemias may need rethinking
2017
science
Futures: Brain evolution
Science ERC grantee Detlev Arendt shares his vision for the next ten years
2017
science
Futures: Genome regulation
Science ERC grantee Eileen Furlong shares her vision for the next ten years
2017
science
Unlocking the secrets of nuclear movements
Science EMBL researchers develop a computer model to explore the movement of nuclei in a multinuclear cell
2017
science
Building labs with flies
Alumni Flies can do a lot for science, inside and outside the lab. EMBL alumna Isabel Palacios explains how
2017
alumni
Study offers approach to treating pain
Science Research on the effect of nerve cell stiffness on sensitivity to touch could lead to new painkillers
2016
science
Cycle of life
Science Paul Nurse’s failed experiment inspired a career that would uncover key mechanisms of cell division
2016
science
Design for life
Lab Matters EMBL’s Petra Riedinger retires after 40 years producing posters, graphics, artwork and more
2016
lab-matters
Chromatin cartographer
Alumni EMBL alumnus Jop Kind reflects on the questions that led him to this year’s John Kendrew Award
2016
alumni
New insights into RNA Polymerase I
Science Cryo EM reconstruction of RNA Polymerase I reveals details of how molecule binds and transcribes DNA
2016
science
Welcome to EMBL: Robert Prevedel
Science Robert Prevedel develops deep-tissue microscopy for scientists to peer deep inside living organisms
2016
science
Watching nuclear pores in growing nuclei
Science Puzzle of nuclear pore formation in growing nuclei solved
2016
science
New tool to control information relay in cells
Science Molecular messengers synthesised to help study how cells respond to outside stimuli
2016
science
Welcome: Alba Diz-Muñoz
Science New group leader combines physics and biology to answer the 'hows' of cell movement
2016
science
How cells bag their rubbish
Science How cells eliminate protein deposits that can lead to neurodegenerative disorders
2016
science
Making cells move towards the light
Science New method enables scientists to use light to direct where cancer cells go
2016
science
The rhythms in life
Science How EMBL scientists are discovering and understanding the waves and rhythms inside us
2016
science
Mothers and daughters
Science 1st real-time video of starfish egg cell eliminating crucial structures, to ensure embryo viability
2016
science
Forever young
Science How stem cells resist change
2016
science
SPIM doctors
Science From initial development to a start-up company: Selective Plane Illumination Microscopy (SPIM) at EMBL.
2015
science
Lighting up development
Science Using lasers to shed light on how tissues get into shape
2015
science
One hard pull
Science Fibres that pull membrane to form a vesicle exert a force that’s 2500 times a yeast cell’s own weight
2015
science
Karsenti wins CNRS gold
Lab Matters Gold medal celebrates Eric Karsenti’s exceptional career and outstanding contributions to biology.
2015
lab-matters
Cellular synergy
Events Alumnus Thomas Vaccari reflects on the first joint symposium with EMBL Monterotondo, in Milan.
2015
events
First, find your membrane
Science Collaboration between scientists reveals collaboration between lipids.
2015
science
Cell machinery wears complex coat
Science 3D imaging unravels COPI coat of cells' transport vesicles.
2015
science
Decades-old cell biology puzzle solved
Science Behaviour of clathrin proteins, crucial for endocytosis, is clarified using new imaging techniques.
2015
science
Dancing with the cells
Science Cells 'dance' as they draw together during early embryo development.
2015
science
Sense of space
Science EMBL scientists demonstrate that spatial constraints are a key factor in determining nucleus size.
2015
science
Destination collaboration
Science Stanford University biophysicist KC Huang on his collaboration with the Typas group in Heidelberg.
2015
science
How cells have got molecules surrounded
Science Ground-breaking microscopy technique gives unprecedented insight into endocytosis.
2015
science
No humans required
Science New fully automated technique enables scientists to chart complex protein networks in living cells.
2015
science
Best of three worlds
Science Combining three different kinds of microscopy to determine how molecules move during endocytosis.
2015
science
Under pressure
Science How strong does a spindle need to be? Videos put cell’s chromosome-separating machinery to the test
2015
science
Beyond sequencing
Science New microscopy-based method goes beyond gene sequencing, pinpointing the cause of disease.
2015
science
Awards & Honours
Lab Matters EMBL scientists regularly receive prestigious awards – meet the latest honourees.
2015
lab-matters
Bacteria’s barrel-building challenge
Science How do E.coli and similar bacteria grow safely? By using barrel-plugs as sensors.
2014
science
How to fix a cellular powerhouse
Science Compound that can restore the function of poorly working mitochondria, with therapeutic potential.
2014
science
Polish connections
Alumni Alumna Anna Bartosik shares insights and hopes for EMBL's newest prospect member state, Poland.
2014
alumni
Chamber of secrets
Science Like sports teams, cells can huddle to communicate in secret and organise group behaviour
2014
science
Breaking boundaries
Science How Nobel-winning work by alumnus Stefan Hell shapes and inspires current EMBL scientists' research.
2014
science
Go with the flow
Science Flow cytometry: finding needles in haystacks
2014
science
Major advance in stem cell technology
Science Researchers produce pristine stem cells, which can be precisely changed into clinically relevant cell types.
2014
science
Drawing on nature
Events PhD Symposium poster reveals how a cell’s inner workings serve as both inspiration and toolkit.
2014
events
Binding bracelet
Science Vasa protein preserves pieces of 'enemy' DNA to help protect the genes of future generations.
2014
science
Embracing cellular complexity
Science Cell biologists "underestimate the complexity" of protein interactions, says Toby Gibson.
2014
science
Picky eaters: how microglia capture their prey
Science A kaleidoscope of molecules is needed to clean up dead brain cells, and failure can have disastrous consequences
2014
science
First, catch your DNA
Science DNA-coralling protein complex in an unexpected bind
2014
science
How immune cells use steroids
Science Genome Campus researchers discover that some immune cells turn themselves off by producing a steroid.
2014
science
Movies for the human genome
Science Name a human gene, and you’ll find a movie online showing you what happens to cells when it is switched off. This is the resource that researchers at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, and their collaborators in the Mitocheck consortium are making freely…
2010
science
A clearer view on biology
Science The European Molecular Biology Laboratory (EMBL) has developed a new computational tool that makes images obtained with cutting-edge microscopes even sharper. The technological advance and its applications are published in this week’s online issue of the journal Nature Methods. Since the…
2007
science
How nature tinkers with the cellular clock
Science The life of a cell is all about growing and dividing at the right time. That is why the cell cycle is one of the most tightly regulated cellular processes. A control system with several layers adjusts when key components of the cell cycle machinery are produced, activated and degraded to make sure…
2006
science
Biology in four dimensions
Science Most things that happen in the cell are the work of ‘molecular machines’ – complexes of proteins that carry out important cellular functions. Until now, scientists didn’t have a clear idea of when proteins form these machines – are these complexes pre-fabricated or put…
2005
science
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