Cute molecules and the scientists who adore them: Veijo Salo
Veijo Salo, postdoc at EMBL Heidelberg, talks about seipin, the cell’s molecular ‘bubble blower’.
PEOPLE & PERSPECTIVES2024
people-perspectives
What we can learn from hungry yeast cells
Scientists at EMBL Heidelberg and University of Virginia revealed a new cellular response to starvation: ribosomes attach to the mitochondrial outer membrane in a very unusual way, via their small subunit. The finding made in yeast might provide insights into how cancer cells survive the harsh…
SCIENCE & TECHNOLOGY2024
science-technology
The forces behind chromosome repulsion and attraction during cell division
EMBL Heidelberg researchers discovered how a protein switches between repelling and gluing chromosomes during cell division. This helps the mother cell to divide the genome equally into two daughter cells and cluster chromosomes inside the daughter nuclei, ensuring a successful cell division.
SCIENCE & TECHNOLOGY2024
science-technology
Structure and function of new lysosome transporter revealed
The group of Christian Löw at EMBL Hamburg and CSSB, and collaborators from the Christian-Albrechts-University Kiel and CNRS & Université Paris Cité worked together to reveal the structure and function of a previously unknown lysosome transporter, MFSD1.
SCIENCE & TECHNOLOGY2024
science-technology
Exploring diversity in cell division
New research by EMBL scientists shows how different modes of cell division used by animals and fungi might have evolved to support diverse life cycles.
SCIENCE & TECHNOLOGY2024
science-technology
Understanding how cells avoid obstacles
EMBL researchers have identified a novel mechanism that allows cells to sense obstacles in their path and avoid them while navigating complex environments.
SCIENCE & TECHNOLOGY2023
sciencescience-technology
New therapies to improve cardiovascular health
EMBL researchers have made new strides into understanding and reversing genetic defects that underlie familial heart disease.
SCIENCE & TECHNOLOGY2023
sciencescience-technology
The power of cell sorting: understanding heart disease, phase separation, plankton, and more
EMBL researchers use a new cell sorting technology to gain new insights into cellular function in health and disease, as well as for other innovative applications.
SCIENCE & TECHNOLOGY2023
sciencescience-technology
The hairy single-celled Tetrahymena provides a work reset
Dey Group holds second annual ‘labbatical’ to step outside daily research tasks with the help of single-celled model organisms.
LAB MATTERSSCIENCE & TECHNOLOGY2023
lab-mattersscience-technology
Spotlight: A giant in action
Physarum polycephalum, a single, giant cell containing tens of thousands of nuclei is large enough to be photographed with a phone.
SCIENCE & TECHNOLOGY2022
picture-of-the-weekscience-technology
Cell sorting enters a new dimension
EMBL researchers, in collaboration with BD Biosciences, have demonstrated a new technology that allows rapid image-based sorting of cells. The new technology represents a major upgrade to flow cytometry and has applications in diverse life science fields.
SCIENCE & TECHNOLOGY2022
sciencescience-technology
A gallery of human RNA polymerases
New structural biology research provides fundamental information critical to understanding enzyme mutations connected to rare diseases and cancers.
SCIENCE & TECHNOLOGY2021
sciencescience-technology
Welcome: Niccolò Banterle
Using gene editing and three types of microscopy, one of EMBL’s newest group leaders is deciphering the functions of one of the smallest molecules involved in cell division, motility, and signalling, known as a centriole.
LAB MATTERSPEOPLE & PERSPECTIVES2021
lab-matterspeople-perspectives
Analysis and sorting with flow cytometry
A technology around since the ‘60s, flow cytometry has increasing applications. New leadership at EMBL’s flow cytometry facilities is looking to ease use, expand training, and encourage more collaboration.
LAB MATTERSSCIENCE & TECHNOLOGY2021
lab-mattersscience-technology
When ‘good’ cells go ‘bad’
If researchers can identify specifically when good cells go bad, they can potentially understand disease better.
SCIENCE & TECHNOLOGY2021
sciencescience-technology
A cellular atlas of an entire worm
EMBL scientists and colleagues have developed an interactive atlas of the entire marine worm Platynereis dumerilii in its larval stage. The PlatyBrowser resource combines high-resolution gene expression data with volume electron microscopy images.
SCIENCE & TECHNOLOGY2021
sciencescience-technology
Cryo-Electron Microscopy Service Platform supports research on protein transport
Giulia Zanetti from the Institute of Structural and Molecular Biology (ISMB) in London explains how the collaboration with the Cryo-Electron Microscopy Service Platform enabled her group to reveal the structure of protein transport complexes.
LAB MATTERSSCIENCE & TECHNOLOGY2021
lab-mattersscience-technology
Welcome: Anna Erzberger
Anna Erzberger, one of EMBL’s newest group leaders, will provide unique perspective as a theoretical biological physicist.
LAB MATTERSPEOPLE & PERSPECTIVES2021
lab-matterspeople-perspectives
Nuclear twins
Captured by EMBL postdoc Arina Rybina, these ‘nuclear twins’ are two daughter nuclei straight after division of a HeLa cell.
SCIENCE & TECHNOLOGY2021
picture-of-the-weekscience-technology
SARS-CoV-2 curtails immune response in the gut
EMBL scientists, together with collaborators from Heidelberg University, have provided further evidence of the gut’s role in COVID-19.
SCIENCE & TECHNOLOGY2021
sciencescience-technology
Painting liver cells
A page from a biologist’s colouring book? EMBL’s new interior wall design? Not quite – a bunch of liver cells, grown in the lab so that scientists can learn about fatty liver disease, or steatosis.
SCIENCE & TECHNOLOGY2021
picture-of-the-weekscience-technology
At the core of the Integrator complex
A new paper from the Galej group at EMBL Grenoble describes the structure of key parts of the Integrator complex, involved in gene expression.
SCIENCE & TECHNOLOGY2021
sciencescience-technology
EMBL group leader Miki Ebisuya receives ERC Consolidator Grant
Funding by the European Research Council (ERC) will support research on the timing of developmental processes in mammals
EMBL ANNOUNCEMENTSLAB MATTERS2020
embl-announcementslab-matters
Scratching the surface on cell differentiation
Scientists in the Diz-Muñoz group at EMBL Heidelberg are working to build understanding of the role that mechanical properties play in affecting cell behaviour – a young and rapidly developing field of study. They have developed and successfully used a highly specialised technique to manipulate…
SCIENCE & TECHNOLOGY2020
sciencescience-technology
Party at the nucleus?
The nucleus of this cell fluoresces in bright green thanks to GFP-labelled nucleoporin proteins. EMBL scientists use engineered nucleoporins as 3D reference standards to improve super-resolution microscopy.
SCIENCE & TECHNOLOGY2020
picture-of-the-weekscience-technology
Human and mouse cells run at different speeds
The internal clock that governs the development of embryos ticks slower for humans than for mice. Differences in the speed of biochemical reactions underlie the differences between species in the tempo of development.
SCIENCE & TECHNOLOGY2020
sciencescience-technology
A tool to improve cancer research
EMBL scientists have created a new, realistic 3D testbed that could help achieve the goal of stopping cancers before they start by studying cancer cells as they first form.
SCIENCE & TECHNOLOGY2020
sciencescience-technology
Taking a closer look at infected cells to better understand COVID-19
EMBL electron microscopy specialists collaborate with researchers from Heidelberg University Hospital to understand the changes occurring in cell structures upon SARS-CoV-2 infection.
SCIENCE & TECHNOLOGY2020
sciencescience-technology
Machine learning finds critical phosphosites
Resource has implications for disease research
SCIENCE & TECHNOLOGY2019
sciencescience-technology
Photo-micropatterning advances structural cell biology
A new technique in cryo-EM
SCIENCE & TECHNOLOGY2019
sciencescience-technology
ATP affects proteome-wide solubility
Scientists develop technology to measure how ATP concentration affects protein solubility in cells
SCIENCE & TECHNOLOGY2019
sciencescience-technology
Understanding early embryo development in mice
How organs form in a mouse embryo
SCIENCE & TECHNOLOGY2019
sciencescience-technology
EMBL in the UK: Wendy Bickmore
Meet Wendy Bickmore, Director of the MRC Human Genetics Unit, who spoke at the EMBL in the UK event
PEOPLE & PERSPECTIVES2018
alumnipeople-perspectives
EMBL in Finland: Marja Makarow
Scientists in Finland met to share ideas and discover research opportunities
CONNECTIONS2018
alumniconnections
The proteins behind hungry cells
EMBL researchers visualise the proteins needed to capture molecules and bring them into a cell
SCIENCE & TECHNOLOGY2018
sciencescience-technology
Welcome: Miki Ebisuya
New group leader at EMBL Barcelona creates artificial biological systems to study animal development
PEOPLE & PERSPECTIVES2018
people-perspectivesscience
EMBL in Italy: Kristina Havas-Cavalletti
More than 80 attendees gathered at the EMBL in Italy event at the FIRC Institute of Molecular Oncology (IFOM) in Milan
PEOPLE & PERSPECTIVES2018
alumnipeople-perspectives
Melina Schuh receives EMBO Gold Medal
EMBL alumna Melina Schuh recognised for excellence in science
PEOPLE & PERSPECTIVES2018
alumnipeople-perspectives
New software makes 3D imaging accessible
Open-source software allows standard microscopes to accurately image 3D structures
SCIENCE & TECHNOLOGY2018
sciencescience-technology
Counting condensins on chromosomes
EMBL scientists count and locate chromosomal proteins during cell duplication
SCIENCE & TECHNOLOGY2018
sciencescience-technology
From blood vessels to blood stem cells
EMBL scientists discover how blood vessel cells become blood stem cells during embryonic development
SCIENCE & TECHNOLOGY2018
sciencescience-technology
DNA replication stress in cancer
Thanos Halazonetis discusses the EMBO/EMBL Symposium: DNA Replication: From Basic Biology to Disease
SCIENCE & TECHNOLOGY2018
eventsscience-technology
Welcome: Sara Cuylen-Häring
New EMBL group leader explores biophysical properties of chromosomes and other cellular assemblies
PEOPLE & PERSPECTIVES2018
people-perspectivesscience
Welcome: Aissam Ikmi
New group leader studies sea anemones to investigate why some animals regenerate better than others
PEOPLE & PERSPECTIVES2018
people-perspectivesscience
Chromosomes don’t need key protein for all their folds
New research reveals that two different mechanisms are responsible for chromosome folding
SCIENCE & TECHNOLOGY2017
sciencescience-technology
Cells grow pores from shrinking holes
New research shows how pores form in the membrane that surrounds a cell’s nucleus
SCIENCE & TECHNOLOGY2017
sciencescience-technology
Science in space
EMBL alumna Sigrid Reinsch trained as a cell biologist – now she helps run experiments in space
PEOPLE & PERSPECTIVES2017
alumnipeople-perspectives
Research highlights
A summary of recent research highlights from EMBL
SCIENCE & TECHNOLOGY2017
sciencescience-technology
Looping the loops: how chromosomes form
EMBL researchers and collaborators unravel how chromosomes form
SCIENCE & TECHNOLOGY2017
sciencescience-technology
Welcome: Justin Crocker
Meet Justin Crocker, EMBL’s new group leader in gene regulation during evolution and development
PEOPLE & PERSPECTIVES2017
people-perspectivesscience
40 years of electron microscopy training at EMBL
Celebrating 40 years since the first EMBO electron microscopy training course
LAB MATTERS2017
eventslab-matters
Open imaging data for biology
The Image Data Resource - prototype of the first open repository linking imaging and molecular data
SCIENCE & TECHNOLOGY2017
sciencescience-technology
Mapping gene expression, cell by cell
EMBL researchers complete a molecular atlas showing gene expression in all cells in an entire animal
SCIENCE & TECHNOLOGY2017
sciencescience-technology
Senses: Silencing noise
Two EMBL researchers are exploring new ways to filter out noise and get to the data they need
SCIENCE & TECHNOLOGY2017
sciencescience-technology
Cell changes drive breast cancer relapse
Hallmarks of residual breat cancer cells suggest new approaches for preventing relapse
SCIENCE & TECHNOLOGY2017
sciencescience-technology
Futures: Phosphatases
ERC grantee Maja Köhn shares her vision for the next ten years
SCIENCE & TECHNOLOGY2017
sciencescience-technology
Illuminating insulin release
EMBL researchers develop an optical method for measuring the release of insulin from single cells
SCIENCE & TECHNOLOGY2017
sciencescience-technology
Structure of key system for TB infection
EMBL scientists add crucial knowledge to understanding of the bacterium that causes tuberculosis
SCIENCE & TECHNOLOGY2017
sciencescience-technology
Blood stem cell differentiation is continuous
Study by EMBL and DKFZ researchers means origins of myeloid leukaemias may need rethinking
SCIENCE & TECHNOLOGY2017
sciencescience-technology
Futures: Brain evolution
ERC grantee Detlev Arendt shares his vision for the next ten years
SCIENCE & TECHNOLOGY2017
sciencescience-technology
Futures: Genome regulation
ERC grantee Eileen Furlong shares her vision for the next ten years
SCIENCE & TECHNOLOGY2017
sciencescience-technology
Unlocking the secrets of nuclear movements
EMBL researchers develop a computer model to explore the movement of nuclei in a multinuclear cell
SCIENCE & TECHNOLOGY2017
sciencescience-technology
Building labs with flies
Flies can do a lot for science, inside and outside the lab. EMBL alumna Isabel Palacios explains how
PEOPLE & PERSPECTIVES2017
alumnipeople-perspectives
Study offers approach to treating pain
Research on the effect of nerve cell stiffness on sensitivity to touch could lead to new painkillers
SCIENCE & TECHNOLOGY2016
sciencescience-technology
Cycle of life
Paul Nurse’s failed experiment inspired a career that would uncover key mechanisms of cell division
SCIENCE & TECHNOLOGY2016
sciencescience-technology
Design for life
EMBL’s Petra Riedinger retires after 40 years producing posters, graphics, artwork and more
LAB MATTERSPEOPLE & PERSPECTIVES2016
lab-matterspeople-perspectives
Chromatin cartographer
EMBL alumnus Jop Kind reflects on the questions that led him to this year’s John Kendrew Award
PEOPLE & PERSPECTIVES2016
alumnipeople-perspectives
New insights into RNA Polymerase I
Cryo EM reconstruction of RNA Polymerase I reveals details of how molecule binds and transcribes DNA
SCIENCE & TECHNOLOGY2016
sciencescience-technology
Welcome to EMBL: Robert Prevedel
Robert Prevedel develops deep-tissue microscopy for scientists to peer deep inside living organisms
PEOPLE & PERSPECTIVES2016
people-perspectivesscience
Watching nuclear pores in growing nuclei
Puzzle of nuclear pore formation in growing nuclei solved
SCIENCE & TECHNOLOGY2016
sciencescience-technology
New tool to control information relay in cells
Molecular messengers synthesised to help study how cells respond to outside stimuli
SCIENCE & TECHNOLOGY2016
sciencescience-technology
Welcome: Alba Diz-Muñoz
New group leader combines physics and biology to answer the 'hows' of cell movement
PEOPLE & PERSPECTIVES2016
people-perspectivesscience
How cells bag their rubbish
How cells eliminate protein deposits that can lead to neurodegenerative disorders
SCIENCE & TECHNOLOGY2016
sciencescience-technology
Making cells move towards the light
New method enables scientists to use light to direct where cancer cells go
SCIENCE & TECHNOLOGY2016
sciencescience-technology
The rhythms in life
How EMBL scientists are discovering and understanding the waves and rhythms inside us
SCIENCE & TECHNOLOGY2016
sciencescience-technology
Mothers and daughters
1st real-time video of starfish egg cell eliminating crucial structures, to ensure embryo viability
SCIENCE & TECHNOLOGY2016
sciencescience-technology
Forever young
How stem cells resist change
SCIENCE & TECHNOLOGY2016
sciencescience-technology
SPIM doctors
From initial development to a start-up company: Selective Plane Illumination Microscopy (SPIM) at EMBL.
SCIENCE & TECHNOLOGY2015
sciencescience-technology
Lighting up development
Using lasers to shed light on how tissues get into shape
SCIENCE & TECHNOLOGY2015
sciencescience-technology
One hard pull
Fibres that pull membrane to form a vesicle exert a force that’s 2500 times a yeast cell’s own weight
SCIENCE & TECHNOLOGY2015
sciencescience-technology
Karsenti wins CNRS gold
Gold medal celebrates Eric Karsenti’s exceptional career and outstanding contributions to biology.
EMBL ANNOUNCEMENTSLAB MATTERS2015
embl-announcementslab-matters
Cellular synergy
Alumnus Thomas Vaccari reflects on the first joint symposium with EMBL Monterotondo, in Milan.
PEOPLE & PERSPECTIVES2015
eventspeople-perspectives
First, find your membrane
Collaboration between scientists reveals collaboration between lipids.
SCIENCE & TECHNOLOGY2015
sciencescience-technology
Cell machinery wears complex coat
3D imaging unravels COPI coat of cells' transport vesicles.
SCIENCE & TECHNOLOGY2015
sciencescience-technology
Decades-old cell biology puzzle solved
Behaviour of clathrin proteins, crucial for endocytosis, is clarified using new imaging techniques.
SCIENCE & TECHNOLOGY2015
sciencescience-technology
Dancing with the cells
Cells 'dance' as they draw together during early embryo development.
SCIENCE & TECHNOLOGY2015
sciencescience-technology
Sense of space
EMBL scientists demonstrate that spatial constraints are a key factor in determining nucleus size.
SCIENCE & TECHNOLOGY2015
sciencescience-technology
Destination collaboration
Stanford University biophysicist KC Huang on his collaboration with the Typas group in Heidelberg.
SCIENCE & TECHNOLOGY2015
sciencescience-technology
How cells have got molecules surrounded
Ground-breaking microscopy technique gives unprecedented insight into endocytosis.
SCIENCE & TECHNOLOGY2015
sciencescience-technology
No humans required
New fully automated technique enables scientists to chart complex protein networks in living cells.
SCIENCE & TECHNOLOGY2015
sciencescience-technology
Best of three worlds
Combining three different kinds of microscopy to determine how molecules move during endocytosis.
SCIENCE & TECHNOLOGY2015
sciencescience-technology
Under pressure
How strong does a spindle need to be? Videos put cell’s chromosome-separating machinery to the test
SCIENCE & TECHNOLOGY2015
sciencescience-technology
Beyond sequencing
New microscopy-based method goes beyond gene sequencing, pinpointing the cause of disease.
SCIENCE & TECHNOLOGY2015
sciencescience-technology
Awards & Honours
EMBL scientists regularly receive prestigious awards – meet the latest honourees.
LAB MATTERS2015
lab-matters
Bacteria’s barrel-building challenge
How do E.coli and similar bacteria grow safely? By using barrel-plugs as sensors.
SCIENCE & TECHNOLOGY2014
sciencescience-technology
How to fix a cellular powerhouse
Compound that can restore the function of poorly working mitochondria, with therapeutic potential.
SCIENCE & TECHNOLOGY2014
sciencescience-technology
Polish connections
Alumna Anna Bartosik shares insights and hopes for EMBL's newest prospect member state, Poland.
LAB MATTERS2014
alumnilab-matters
Chamber of secrets
Like sports teams, cells can huddle to communicate in secret and organise group behaviour
SCIENCE & TECHNOLOGY2014
sciencescience-technology
Breaking boundaries
How Nobel-winning work by alumnus Stefan Hell shapes and inspires current EMBL scientists' research.
SCIENCE & TECHNOLOGY2014
sciencescience-technology
Go with the flow
Flow cytometry: finding needles in haystacks
SCIENCE & TECHNOLOGY2014
sciencescience-technology
Major advance in stem cell technology
Researchers produce pristine stem cells, which can be precisely changed into clinically relevant cell types.
SCIENCE & TECHNOLOGY2014
sciencescience-technology
Drawing on nature
PhD Symposium poster reveals how a cell’s inner workings serve as both inspiration and toolkit.
2014
events
Binding bracelet
Vasa protein preserves pieces of 'enemy' DNA to help protect the genes of future generations.
SCIENCE & TECHNOLOGY2014
sciencescience-technology
Embracing cellular complexity
Cell biologists "underestimate the complexity" of protein interactions, says Toby Gibson.
SCIENCE & TECHNOLOGY2014
sciencescience-technology
Picky eaters: how microglia capture their prey
A kaleidoscope of molecules is needed to clean up dead brain cells, and failure can have disastrous consequences
SCIENCE & TECHNOLOGY2014
sciencescience-technology
First, catch your DNA
DNA-coralling protein complex in an unexpected bind
SCIENCE & TECHNOLOGY2014
sciencescience-technology
How immune cells use steroids
Genome Campus researchers discover that some immune cells turn themselves off by producing a steroid.
SCIENCE & TECHNOLOGY2014
sciencescience-technology
Movies for the human genome
Name a human gene, and you’ll find a movie online showing you what happens to cells when it is switched off. This is the resource that researchers at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, and their collaborators in the Mitocheck consortium are making freely…
SCIENCE & TECHNOLOGY2010
sciencescience-technology
A clearer view on biology
The European Molecular Biology Laboratory (EMBL) has developed a new computational tool that makes images obtained with cutting-edge microscopes even sharper. The technological advance and its applications are published in this week’s online issue of the journal Nature Methods. Since the…
SCIENCE & TECHNOLOGY2007
sciencescience-technology
How nature tinkers with the cellular clock
The life of a cell is all about growing and dividing at the right time. That is why the cell cycle is one of the most tightly regulated cellular processes. A control system with several layers adjusts when key components of the cell cycle machinery are produced, activated and degraded to make sure…
SCIENCE & TECHNOLOGY2006
sciencescience-technology
Biology in four dimensions
Most things that happen in the cell are the work of ‘molecular machines’ – complexes of proteins that carry out important cellular functions. Until now, scientists didn’t have a clear idea of when proteins form these machines – are these complexes pre-fabricated or put…
SCIENCE & TECHNOLOGY2005
sciencescience-technology
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