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development

Year
15 November 2023

Why time is of the essence in development

EMBLetc EMBL developmental biologists – with help from other disciplines – pursue the significance of time, timing, and transitions in organisms during their development

2023

31 August 2023 Part of a fruit fly embryo imaged against a dark background, with nuclei stained with DAPI (white), and a cluster of pole cells, marked by Vasa protein (yellow)

Spotlight: Off to the pole

Picture of the week, Science For a fruit fly embryo to develop correctly, key factors need to get to the right place at the right time – a journey that starts in the developing egg, as seen in this image from the Ephrussi Group at EMBL Heidelberg

2023

picture-of-the-weekscience

5 August 2022 A rod-like structure with green and magenta segments representing cellular markers.

Making patterns visible

Science How do gene expression patterns result in the generation of different cell types? Scientists at EMBL Heidelberg used the zebrafish notochord to find out.

2022

science

4 August 2022 An illustration provides representation of fingers hovering over a cell phone

Zooming in to get the full picture

Science EMBL and UW researchers plus additional collaborators have constructed a complete map of fruit fly embryonic development using machine learning. This research is foundational to better understanding overall embryo development in other species, including humans.

2022

science

23 March 2022 Two Drosophila embryos stained with fluorescent dye on a purple background that indicates either solid or liquid state

From liquid to solid to drive development

Science Condensates are membraneless organelles that control specific functions within a cell. Scientists at EMBL Heidelberg have shown how the physical state of condensates can influence biological function.

2022

science

4 March 2022 A gloved hand holds a slide with visible wells containing Matrigel immersed in culture medium. A magnified close-up shows a mouse embryo developing over the course of 48 hours

A 3D culture model to study embryo growth

Science A recent study by EMBL researchers proposes a new method to grow early embryos in the laboratory. With a 3D culture set-up, scientists can closely monitor the changes embryos undergo around the time of implantation.

2022

science

25 February 2022 Three colourful overlapping circles arranged in a row, a fruit-fly embryo being visible within each. Small circles within the embryos represent cell lineages.

Converging lenses on embryo development

Science Researchers from the Furlong group at EMBL have come up with a way to observe the development of fruit-fly embryos simultaneously at the genetic and cellular levels, generating a high-resolution and integrated view of how different cell lineages form.

2022

science

9 December 2021 Portrait photo of Eileen Furlong against blue-green background.

Eileen Furlong honoured with Leibniz Prize

Lab Matters EMBL Senior Scientist and Head of the Genome Biology Unit is among the researchers honoured for outstanding work by the German Research Foundation (Deutsche Forschungsgemeinschaft, DFG).

2021

lab-matters

16 June 2020 Composite image of fly larvae organs making up a flower

From fly to flower

Picture of the week In this composite image, visual artist Mona Kakanj assembled three different biological structures in fly larvae into a flower. The original images were taken as part of a research project by Parisa Kakanj in Maria Leptin’s group.

2020

picture-of-the-week

15 May 2020 Cell division

Tracing the origins of cells

Science Researchers from the Sharpe group at EMBL Barcelona have published a method to track the developmental history of a cell using the gene editing tool CRISPR–Cas9, but without the need to create transgenic organisms.

2020

science

11 February 2020

Breathe in, breathe out

Picture of the week This image shows the tracheal system of a live fruit fly larva. Daniel Rios from the Leptin Group and Dimitri Kromm from the Hufnagel Group used this advanced microscope to investigate the dynamics of tracheal cells during development.

2020

picture-of-the-week

29 November 2019 Choanocyte chamber of sponge, with neuroid cell

Neural pathways

Science Exploring the diverse routes by which EMBL scientists are driving forward neurobiology

2019

science

1 July 2019 The dynamic process of cell division.

Drawing knowledge

Science A conversation about art-science collaborations and the importance of drawing in biology.

2019

science

29 April 2019 This illustration, based on real data shows the heart of a Japanese rice fish. The green and blue laser beams demonstrate how the newly developed 3D imaging microscope is scanning the heart.

New 3D microscope

Science A newly developed 3D microscope visualises fast biological processes better than ever.

2019

science

8 January 2018 A photo of new EMBL Heidelberg group leader Aissam Ikmi.

Welcome: Aissam Ikmi

Science New group leader studies sea anemones to investigate why some animals regenerate better than others

2018

science

21 September 2017

Fish on fire

Science New study by Paola Kuri and Maria Leptin shows how inflammation happens in zebrafish in real time

2017

science

11 August 2017

Welcome: Justin Crocker

Science Meet Justin Crocker, EMBL’s new group leader in gene regulation during evolution and development

2017

science

2 March 2017

Metabolism matters

Science Differentiated and undifferentiated cells get energy in different ways, sensor made at EMBL shows

2017

science

24 November 2016 SPIM image of Medaka juveniles. Photo: EMBL/Philipp Keller

Thinking in 3D

Alumni Ernst Stelzer earns 2016 Lennart Philipson award for advances in light sheet microscopy

2016

alumni

24 November 2016

Chromatin cartographer

Alumni EMBL alumnus Jop Kind reflects on the questions that led him to this year’s John Kendrew Award

2016

alumni

3 November 2016

Spiral growth

Science What happens when plant's leaf-placing feedback loop isn't quite right

2016

science

20 October 2016

Diving into Autumn

Events Participants learn about EMBL’s ocean biodiversity research at the Fall Gala

2016

events

21 April 2016 EMBL scientists are discovering and understanding the waves and rhythms inside us. ILLUSTRATION: Aad Goudappel, Rotterdam

The rhythms in life

Science How EMBL scientists are discovering and understanding the waves and rhythms inside us

2016

science

24 March 2016 Zernicka-Goetz lab, University of Cambridge

Foetus, or placenta?

Science Subtle genetic differences destine cells to placenta or animal, very early in embryo development

2016

science

21 March 2016 First complete, real-time recording of starfish egg cell eliminating centrioles shows it handles mature ‘mother’ centrioles (green) and immature ‘daughter’ centrioles (purple) differently.

Mothers and daughters

Science 1st real-time video of starfish egg cell eliminating crucial structures, to ensure embryo viability

2016

science

12 February 2016 Cells formed circles where blinking happened in a wave, rolling outwards from the centre. IMAGE: EMBL/C.Tsiairis

In sync

Science What do cells in an embryo have in common with schools of fish, swarms of fireflies, and applauding audiences?

2016

science

11 February 2016 The 3D structure shows how two transcription factors influence one another’s binding to a specific stretch of DNA – an interaction that is crucial for a heart to develop healthily. IMAGE: EMBL/C.Müller

True Love

Science How transcription factors interact to create a heart

2016

science

26 January 2015 ILLUSTRATION: AAD GOUDAPPEL

Cell control in a flash

Science From using light to control brain activity to illuminating fruit fly development and mice’s sense of touch

2015

science

23 October 2014

Chamber of secrets

Science Like sports teams, cells can huddle to communicate in secret and organise group behaviour

2014

science

17 October 2014 Five-armed starfish

Superstars of science

Science From anemones to starfish, sea creatures are helping understand development, evolution and more.

2014

science

6 August 2014

Clarity in the cold

Science How fruit flies beat the cold, plus the value of precisely controlled experiments and detailed analysis

2014

science

8 May 2014 Microscopy image

Remodelling the cell

Science The balance behind membrane changes that turn one cell into 6000 as a fruit fly embryo develops

2014

science

19 December 2012

Sync to grow

Science Gene expression wave in the lower part of the future vertebrae column of a mammalian embryo. As the wave goes forward, new pre-vertebrae are formed and the future vertebrae column elongates. (Image and video credit: Nature) In a nutshell: The size of pre-vertebrae in a mammalian embryo is…

2012

science

10 December 2009 These microscopy images demonstrate the effects of Notch signalling on the hearts of newborn mice (top) and of adult mice after a heart attack (bottom). In a normal neonatal heart (top left), the two major heart chambers (ventricles) are clearly separated by tissue (septum). But when Notch signalling was inactivated in an embryo’s heart muscle cells, the septum between the ventricles of the newborn mouse’s heart was incomplete (asterisk). The same defect commonly occurs in humans with congenital heart disease, often leading to circulatory distress. In the images of adult hearts (bottom), healthy tissue is shown in red and damaged tissue in blue. Normally (bottom left), a heart attack causes extensive tissue damage to the left ventricle (right-hand cavity), but mice in which Notch was re-activated after the heart attack had reduced tissue damage (bottom right) and improved cardiac function. Image credit: EMBL

From fruit fly wings to heart failure. Why Not(ch)?

Science Almost a century after it was discovered in fruit flies with notches in their wings, the Notch signalling pathway may come to play an important role in the recovery from heart attacks. In a study published today in Circulation Research, scientists at the European Molecular Biology Laboratory (EMBL)…

2009

science

3 September 2006

Lost in the labyrinth

Science Blood cells have limited lifespans, which means that they must be continually replaced by calling up reserves and turning these into the blood cell types needed by the body. Claus Nerlov and his colleagues at the European Molecular Biology Laboratory (EMBL) unit in Monterotondo, Italy, in…

2006

science

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