Facilitating drug discovery against COVID-19
Science A collaboration between EMBL Grenoble and EBRIS scientists led to the characterisation of a new compound with promising activity against SARS-CoV-2 variants.
2023
science
Behind the scenes of innovation
EMBLetc EMBL Grenoble technology teams provide a sneak peek into their latest collaborative project in structural biology services: the complete automation of an integral step in X-ray crystallography.
2023
Welcome: Gergely Papp
Lab Matters Together with his team, Gergely Papp pushes the frontiers of technology development in the field of structural biology.
2023
lab-matters
New molecular insights on medical cannabis
Science EMBL Grenoble researchers have investigated the interaction between THC and some proteins it might bind to. In a recent study, they showed in vitro that THC inhibits an important human enzyme called autotaxin.
2023
science
Teaming up to drive forward time-resolved crystallography
Lab Matters The recent construction of the new ID29 beamline in Grenoble is pioneering a new way of doing experiments in time-resolved crystallography and opening up technology transfer possibilities
2022
lab-matters
Droplet beauty
Picture of the week Scientists at EMBL Hamburg use droplets of protein solution to grow protein crystals. By exposing the crystals to X-rays, they are able to determine the protein’s molecular structure.
2021
picture-of-the-week
Purity, beauty, and perfection
Picture of the week The regular structures of crystals are a source of inspiration and fascination to us humans. While the crystals in this picture were not grown in nature, but instead by Petra Drncova from EMBL Grenoble, they share the same attributes as those found in nature.
2021
picture-of-the-week
ALPX – smart crystallography
Lab Matters The CrystalDirect® technology, combined with the web-based CRIMS software enable a fully automated, remote-controlled protein-to-structure pipeline.
2020
lab-matters
Genetic cut and paste at atomic resolution
Science Researchers in the Marcia group at EMBL Grenoble and the De Vivo lab at the Italian Institute of Technology in Genoa have obtained some of the most detailed ever snapshots of the splicing process in systems known as group II self-splicing introns. The new insights will help scientists to develop…
2020
science
Responding to health threats posed by coronaviruses
Science By re-opening the High-Throughput Crystallisation (HTX) lab at EMBL Grenoble, EMBL is supporting structural biology projects to respond to the health threats posed by coronaviruses.
2020
science
Remote access to EMBL structural biology pipelines to support research on SARS-CoV-2
Science The Marquez Team has restarted operations at the High-Throughput Crystallisation (HTX) lab at EMBL Grenoble. The team has developed a fully automated protein-to-structure pipeline, which can be operated remotely and provides virtual access to the facilities.
2020
science
EMBL and Tara: Marseille
Events From 27–30 September, Tara will be docked in the port of Marseille, France’s second largest city.
2019
events
Happy hour for time-resolved crystallography
Science Researchers from Hamburg simplify time-resolved X-ray crystallography
2019
science
EMBL and Tara: Hamburg
Events EMBL Hamburg and Tara raise awareness of the risks of microplastic pollution and global infection
2019
events
Structure of prodrug-transporter complex revealed
Science Scientists develop structural model that could help in the development of drugs with increased absorption rates
2019
science
Time-resolved X-ray crystallography simplified
Science Speeding up time-resolved X-ray crystallography with EMBL beamline P14
2018
science
ARP/wARP 8.0 released
Lab Matters Researchers at EMBL Hamburg have released the next generation of their ARP/wARP software
2018
lab-matters
Potential way to limit antibiotic resistance
Science EMBL scientists unravel the molecular basis of a major antibiotic resistance transfer mechanism
2018
science
Beamline ID23-2 tools up for ESRF upgrade
Lab Matters EMBL instrumentation teams adapting tech to run biological experiments on the synchrotron after its upgrade
2018
lab-matters
One way crossing across the midline
Science EMBL researchers solve a decades-long debate on a key process for brain and embryo-development
2018
science
Futures: Unravelling influenza
Science ERC grantee Stephen Cusack shares his vision for the next ten years
2017
science
Hands-on science inspires Hamburg
Events 20,000 visitors get sneak peek at giant particle accelerators at DESY DAY in Hamburg
2017
events
CSSB: A new approach to infectious disease
Science Inside the Centre for Structural Systems Biology
2017
science
EMBL and ESRF renew collaboration agreement
Lab Matters EMBL and the European synchrotron ESRF extend their Joint Structural Biology Group
2017
lab-matters
Looping the loops: how chromosomes form
Science EMBL researchers and collaborators unravel how chromosomes form
2017
science
The future is bright as XFEL opens its doors
Science Newly opened European X-Ray Free-Electron Laser celebrates start of user operations
2017
science
Solving the nucleosome: twenty years on
Events Tim Richmond looks back on the work that revealed the high-resolution structure of the nucleosome
2017
events
Beamline 14’s legacy
Lab Matters Beamline BM14 in Grenoble shuts down, continues collaboration with India
2017
lab-matters
Welcome: Wojciech Galej
Science New group leader Wojciech Galej investigates RNA-protein complexes involved in gene expression
2017
science
Happy anniversary, PDBe!
Lab Matters Ewan Birney's nine "Structures of Christmas" celebrate 20 years of PDBe
2016
lab-matters
New Crystallography platform inaugurated
Lab Matters A new crystallography platform in Grenoble opens the door to new technological developments
2016
lab-matters
Catching the chaperone in the act
Science How Christian Löw’s failed experiment led to an unexpected scientific journey
2016
science
New drug candidate unleashed for TB
Science EMBL researchers help to design a lead compound active against four different pathogens
2016
science
Opinion: 2006, a year of champagne
Lab Matters Stephen Cusack looks back on the early days of his collaboration with Anacor developing anti-infectives
2016
lab-matters
Opinion: A journey from bench to clinical trials
Lab Matters Andrés Palencia on the design of compounds that may help fight drug-resistant TB and more
2016
lab-matters
Taking crystallography to the fourth dimension
Science Collaborating to take crystallography into a new time dimension
2016
science
Atomic proportions
Science EMBL and ESRF scientists and mechanics work together on upgrade for one of Europe’s big X-ray sources
2016
science
Blocking the waste disposal unit
Science Detailed structure paves the way for more effective cancer therapies
2016
science
Leading the way in time-resolved crystallography
Science Establishing a programme of research, development and user services for time-resolved crystallography
2016
science
Enzyme with a dual-purpose loop
Science Unexpected results: structure of DAPK enzyme reveals dual-purpose loop
2016
science
The man behind the machine
Science Florent Cipriani talks about his passion for developing beamline instrumentation
2016
science
Crystals in the beamlight
Science CrystalDirect, developed at EMBL, automates crystal preparation for X-ray analysis
2016
science
A cohesive structure
Science Structural insights into how cohesin keeps DNA together during the cell cycle
2016
science
True Love
Science How transcription factors interact to create a heart
2016
science
How to make a protein happy
Science Protein screens developed at EMBL Hamburg now commercially available
2016
science
The cellular crystal factory
Science Hamburg collaborators analyse protein crystals inside the cells that made them.
2016
science
One gene, two proteins, one complex
Science Further insights into how viral enzymes degrade the cell walls of Clostridia bacteria.
2016
science
High-throughput event
Events Energy, enthusiasm and endurance on tap as thousands attend 12-hour Hamburg Night of Science.
2015
events
MASSIFly efficient
Science MASSIF-1 processes its 10,000th crystal, less than one year after the beamline became operational.
2015
science
Oskar’s structure revealed
Science 3D structure of Oskar protein gives first molecular insight into how it functions.
2015
science
Building bridges with BioStruct-X
Events Industrial partners and BioStruct-X facility members gather for Workshop at EMBL Hamburg.
2015
events
The curious case of the bi-specific enzyme
Science A puzzling peculiarity resolved by Hamburg’s Sample Preparation and Characterisation facility.
2015
science
From mountains to molecules
Events Staff, alumni, partners and more meet at EMBL Grenoble to celebrate Outstation's 40th anniversary.
2015
events
It runs in the family
Science Detailed structural study shows distantly related viruses share a common machinery for replication.
2015
science
Stephen Cusack elected to the Royal Society
Lab Matters Stephen Cusack, head of EMBL Grenoble, among 47 new Royal Society fellows.
2015
lab-matters
Grenoble anniversary symposium: join us!
Alumni EMBL Grenoble celebrates 40 years with a symposium for staff, alumni and facility users on 4–5 June.
2015
alumni
Shining light onto the fabric of life
Events First LearningLAB of 2015 makes science of protein structure crystal clear for 22 teachers.
2015
events
Light years ahead
Science As EMBL Hamburg celebrates 40 years, we explore the past, present and future of crystallography.
2015
science
It all started with muscle…
Alumni Ken Holmes, one of the visionaries behind EMBL and EMBL Hamburg, looks back to where it all began.
2015
alumni
Welcome: Marco Marcia
Science New group leader Marco Marcia aims to broaden horizons while mapping molecules.
2015
science
Lighting the way
Events EMBL Hamburg celebrates four decades of vision, pioneering research and beamline services.
2014
events
MASSIF step forward
Science In two months, 2.3 million diffraction images collected on new, fully automated ESRF/EMBL beamline.
2014
science
20 years in the making
Science First complete picture of flu virus polymerase. A story of two decades of blood, sweat and sneezes.
2014
science
Zombies and crystals
Events Open Day in Grenoble celebrates crystallography for the Fête de la Science.
2014
events
PEPC recipe for success
Events How to make good quality samples for good quality structural biology experiments.
2014
events
Hamburg anniversary symposium: Preview
Events An interview with keynote speaker Michael Rossmann.
2014
events
Binding bracelet
Science Vasa protein preserves pieces of 'enemy' DNA to help protect the genes of future generations.
2014
science
International connections
Science How a single molecule can attract and repel growing brain connections
2014
science
Fighting bacteria – with viruses
Science Molecular switch enables viruses to destroy C.diff bacteria – potential alternative to antibiotics
2014
science
The future’s bright
Science Surprising protein from a flu-like virus is 10 000th ESRF structure
2014
science
The shape of things to come
Science New ways of handling and distributing data at PDBe to tackle ever larger and more complex proteins
2014
science
Five for the future
Lab Matters Scientists from EMBL's five sites reflect on the opportunities and challenges that might lie ahead
2014
lab-matters
New high-throughput crystallization facility at EMBL Hamburg to give boost to structural biology community
Lab Matters Today the European Molecular Biology Laboratory (EMBL) opens a new highthroughput crystallization facility at its Outstation located on the campus of the German Synchrotron Radiation Facility (DESY) in Hamburg, Germany. The facility, made possible by major funds from the German Ministry for Science…
2005
lab-matters
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