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Health

Tuberculosis – caused by Mycobacterium tuberculosis – is a potentially fatal contagious disease that can affect almost any part of the body but is mainly an infection of the lungs

Better tools for exploring TB protein structures

How an EMBL team is making and sharing tools to explore tuberculosis protein structures

By Rosemary Wilson

Science

HPN-DREAM breast cancer network inference challenge

DREAM shadows: chasing down disease networks

“It’s a bit like drawing a picture of an intricate object just by looking at its shadow on the wall."

By Mary Todd Bergman

Science

The 3D structure shows how two transcription factors influence one another’s binding to a specific stretch of DNA – an interaction that is crucial for a heart to develop healthily. IMAGE: EMBL/C.Müller

True Love

How transcription factors interact to create a heart

By Guest author(s)

Science

A peroxisome containing protein crystals is hit by a free-electron laser. IMAGE: EMBL/CFEL, Thomas Seine

The cellular crystal factory

Hamburg collaborators analyse protein crystals inside the cells that made them.

By Rosemary Wilson

Science

Full length CTP1L protein (green) in complex with truncated C-terminal domain (violet). IMAGE: Rob Meijers

One gene, two proteins, one complex

Further insights into how viral enzymes degrade the cell walls of Clostridia bacteria.

By Rosemary Wilson

Science

New web interface, launched by GSK, EMBL-EBI and Wellcome Trust Sanger Institute.

Target Validation platform launches

Identifying evidence-based relationships between drug targets and diseases.

By Mary Todd Bergman

Lab Matters

Gut bacteria are more affected by metformin than by the type-2 diabetes it is prescribed to treat. IMAGE: Courtesy of Pacific Northwest National Laboratory (BY-NC-SA)

Drugging bacteria

Commonly used diabetes drug metformin impacts gut bacteria more than disease itself

By Sonia Furtado Neves

Science

IMAGE: EMBL-EBI/Spencer Phillips

What makes us human? Or not…

From jumping genes to organ transplants, the non-human features that make us human.

By Isabelle Kling

Science

Awards & Honours

EMBL scientists regularly receive prestigious awards – meet the latest honourees.

By Chloe Cross

Lab Matters

Two superimposed proteins, with regions with shared molecular similarity presumed to interact with our immune system highlighted in blue and red respectively. CREDIT: N Furnham.

Allergy: the price of immunity?

Findings help demonstrate the evolutionary basis for allergy.

By Mary Todd Bergman

Science

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