27 March 2024
Updates from data resources
The SARS-CoV-2 Data Hubs are a set of tools coupled with infrastructure that support four components: the submission, analysis, presentation and visualisation of SARS-CoV-2 raw read data, and its resulting analyses. What makes Data Hubs attractive is a unique set of features: A new publication in…
2024
updates-from-data-resources
16 October 2023
Research highlights
The Lees group develops a tool that can scale up bacterial genome annotation.
21 September 2022
Announcements, Connections, Science
The Federated EGA is set to improve access to sensitive human data in a safe and secure way.
2022
announcementsconnectionsscience
18 July 2022
Science, Science & Technology
EMBL researchers now understand the function of an elusive small DNA in bacteria and have developed a tool that can be used to better understand what might ‘switch on’ bacterial immune defences.
2022
sciencescience-technology
6 May 2022
Science, Science & Technology
Researchers at EMBL Heidelberg found that inversions in the human genome are more common than previously thought, which impacts our understanding of certain genetic diseases.
2022
sciencescience-technology
25 April 2022
Lab Matters, Perspectives
Ewan Birney discusses the input of both genetics and our environment in making us who we are
2022
lab-mattersperspectives
23 February 2022
Announcements, Science, Science & Technology
Scientists urge the adoption of a sensible international policy for digital sequence information.
2022
announcementssciencescience-technology
25 August 2020
Picture of the week, Science & Technology
Beautiful flashes of blue colour help light the way for researchers to study cells in fruit fly larva that provide oxygen to tissues.
2020
picture-of-the-weekscience-technology
5 August 2020
Science, Science & Technology
A global team of researchers including the Flicek Team at EMBL-EBI has partnered up with the Māori tribe Ngātiwai to sequence the genome of the tuatara, a rare reptile endemic to New Zealand.
2020
sciencescience-technology
3 August 2020
Science, Science & Technology
The human genome harbours about 19 000 protein-coding genes, many of which still have no known function. As scientists unveil the secrets of our DNA, they come across novel genes that they need to refer to using a unique name. The Human Genome Organisation’s Gene Nomenclature Committee (HGNC) at…
2020
sciencescience-technology
24 June 2020
Science, Science & Technology
DNA damage caused by chemical mutagens is not repaired immediately and can create more genetic diversity in tumours.
2020
sciencescience-technology
6 May 2020
Science, Science & Technology
DNA mutations are caused by a combination of DNA damage and repair, shows study by EMBL-EBI and collaborators.
2020
sciencescience-technology
4 February 2020
Science, Science & Technology
New resource that categorises genes essential for supporting life could be used to identify rare disease mutations
2020
sciencescience-technology
21 January 2020
Events, Science & Technology
Dame Janet Thornton presents the 2019 EMBL Insight Lecture: Ageing and disease – what is the link?
2020
eventsscience-technology
18 October 2019
Science, Science & Technology
Funding awarded to EMBL-EBI for tuberculosis monitoring tool
2019
sciencescience-technology
9 July 2019
Science, Science & Technology
What CRISPR may bring for the future of biology, and how it is used at EMBL
2019
sciencescience-technology
27 June 2019
Events, Lab Matters
Nobel prize laureate Susumu Tonegawa describes his work in memory research over the past decade
18 March 2019
People & Perspectives, Science
New EMBL group leader explores what neurobiology can teach us about what it means to be human
2019
people-perspectivesscience
4 February 2019
Science, Science & Technology
A new database of bacteria in the human microbiome is the most comprehensive to date.
2019
sciencescience-technology
4 February 2019
Science, Science & Technology
New search engine allows researchers to identify antibiotic resistance genes or mutations in real time
2019
sciencescience-technology
31 January 2019
Lab Matters
Enhancing the world's bioinformatics infrastructure
17 December 2018
Events, People & Perspectives
What genetics can tell us about the structure of ancient human populations
2018
eventspeople-perspectives
26 November 2018
Science, Science & Technology
New algorithm will enhance understanding of relationship between genotype and environmental factors
2018
sciencescience-technology
16 October 2018
Science, Science & Technology
How embryonic stem cells develop into the germ line
2018
sciencescience-technology
23 August 2018
Science, Science & Technology
Large-scale systematic analysis explores how inherited genome affects drug response of cancer cells
2018
sciencescience-technology
20 June 2018
Science, Science & Technology
New computational method uses multi-omics analysis for personalised medicine
2018
sciencescience-technology
31 May 2018
Science, Science & Technology
Of mice and gorillas: using mouse data for conservation
2018
sciencescience-technology
28 May 2018
People & Perspectives, Science
EMBL’s next Director General reflects on the questions that drive her research
2018
people-perspectivesscience
23 May 2018
Science, Science & Technology
EMBL group leader Jan Korbel reflects on his scientific origins and current research
2018
sciencescience-technology
9 May 2018
Lab Matters, People & Perspectives
EMBL alumna, Èlia Benito-Gutiérrez, on how her research and career evolved after searching the seas
2018
lab-matterspeople-perspectives
6 March 2018
Science, Science & Technology
Is depression in your genes?
2018
sciencescience-technology
12 February 2018
Science, Science & Technology
Network of genes linked to development of diabetes
2018
sciencescience-technology
8 January 2018
People & Perspectives, Science
New group leader studies sea anemones to investigate why some animals regenerate better than others
2018
people-perspectivesscience
5 December 2017
Lab Matters, People & Perspectives
Curious about what goes on in EMBL’s Fly Room? Prepare to be a fly on the wall
2017
lab-matterspeople-perspectives
4 December 2017
People & Perspectives, Science
New group leader based in Grenoble aims to unveil the mechanisms of RNA editing
2017
people-perspectivesscience
2 November 2017
Science
Five things researchers have learned from bizarre fruit flies
26 June 2017
Science, Science & Technology
IMPC explains how much the sex of animals is misdirecting research results
2017
sciencescience-technology
26 June 2017
Science, Science & Technology
EMBL-EBI and IMPC characterised over 3000 mouse genes, revealing new gene associations with disease
2017
sciencescience-technology
13 April 2017
Science, Science & Technology
EMBL-EBI researchers identify mouse epigenetic clock that could help scientists understand ageing
2017
sciencescience-technology
31 March 2017
Science, Science & Technology
Researchers use single-cell sequencing to understand how cells age
2017
sciencescience-technology
26 January 2017
Science, Science & Technology
Healing and anxiety are influenced by the genetics of one’s social partners
2017
sciencescience-technology
7 December 2016
Science, Science & Technology
Paul Nurse’s failed experiment inspired a career that would uncover key mechanisms of cell division
2016
sciencescience-technology
1 December 2016
Lab Matters, People & Perspectives
EMBL’s Petra Riedinger retires after 40 years producing posters, graphics, artwork and more
2016
lab-matterspeople-perspectives
30 September 2016
Science, Science & Technology
IMPC study identifies 410 genes essential to life in the mouse, providing a window on human disease
2016
sciencescience-technology
30 August 2016
Science, Science & Technology
Emmanuelle Charpentier sheds light on how CRISPR–Cas9 went from side project to global revolution
2016
sciencescience-technology
9 December 2015
Events
Two PhD students sink their teeth into the science and speculations of Jurassic Park.
2 October 2015
Science
1000 Genomes Project pushed technologies and knowledge forward to understand what is 'normal' human genetic variation
30 September 2015
Science
Missing a gene may not be a big deal – a conclusion from global catalogue of genetic changes.
29 September 2015
Events
EMBL-Wellcome Genome Campus events collaboration showcases open, application-based science.
20 August 2015
Science
EMBL scientists map ‘switches’ for distant control of gene expression.
17 July 2015
Events
Web of lies? Science Movie Night reveals science behind the most famous spider bite in film history.
9 July 2015
Science
European team identify mechanism for producing piRNAs that silence jumping genes in germline cells.
16 June 2015
Science
Researchers at EMBL-EBI speed up complex GWAS analyses with new method and algorithm.
4 June 2015
Science
Decaying RNA molecules tell a story that could add more chapters to the study of ribosomes.
15 April 2015
Alumni
Exploring the science and magic of Lil Bub – alumna launches project to sequence the ‘Lilbubome’.
4 February 2015
Science
New microscopy-based method goes beyond gene sequencing, pinpointing the cause of disease.
8 January 2015
Lab Matters
EMBL-EBI supports relaunch of yourgenome.org, to bring genetics advances to a wider audience.
18 December 2014
Science
Compound that can restore the function of poorly working mitochondria, with therapeutic potential.
17 November 2014
Science
Whether it’s information or people, the art of connecting is key to new group leader Judith Zaugg
14 October 2014
Events
Experts from multiple fields come together to understand how the instructions in genes are read
15 September 2014
Events
EMBL-EBI hosts successful first EMBO Practical Course in Genotype to Phenotype Mapping.
2 July 2014
Science
Surprising finding: enhancers find their targets long before activation in Drosophila embryos
1 July 2014
Lab Matters
School ambassadors show next generation that scientists are more ‘role model’ than ‘mad professor’
1 July 2014
Lab Matters
Scientists from EMBL's five sites reflect on the opportunities and challenges that might lie ahead
25 June 2014
Science, Science & Technology
Enabling neighbours: intact genes can cause cancer when placed near "enhancing" regions of DNA
2014
sciencescience-technology
25 May 2014
Science, Science & Technology
How a DNA stretch influences face formation and contributes to common congenital malformations
2014
sciencescience-technology
9 May 2014
Science, Science & Technology
Genome Campus researchers discover that some immune cells turn themselves off by producing a steroid.
2014
sciencescience-technology
24 April 2014
Science, Science & Technology
Tsetse fly genome sequenced; scientists hope to find new ways to control sleeping sickness.
2014
sciencescience-technology
12 September 2013
Science, Science & Technology
Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg and Regensburg University, both in Germany, and the University of Lisboa, in Portugal, have discovered a promising potential drug target for cystic fibrosis. Their work, published online today in Cell, also uncovers a…
2013
sciencescience-technology
19 December 2012
Science
Gene expression wave in the lower part of the future vertebrae column of a mammalian embryo. As the wave goes forward, new pre-vertebrae are formed and the future vertebrae column elongates. (Image and video credit: Nature) In a nutshell: The size of pre-vertebrae in a mammalian embryo is…
5 December 2012
Science
In a nutshell : The gut metagenome is the collection of all the genomes of all the microbes in the human intestinal tract : it is specific to each human, like a second genetic signature At least in healthy humans, this personal metagenome is stable over time The gut metagenome is…
31 October 2012
Science
In a nutshell: 1st map combining human genetic variation at different scales – from single letters to large chunks Based on genomes of 1092 healthy people from Europe, the Americas and East Asia Could help identify genetic causes of disease, rather than just links Data made freely available in…
3 June 2012
Science
Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have conducted the first comprehensive census of human cells’ export workers. In a study published online today in Nature Cell Biology, they found an unexpected variety of genes involved in transporting…
31 May 2012
Science
In one of the most famous faux pas of exploration, Columbus set sail for India and instead ‘discovered’ America. Similarly, when scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, set out to find enzymes – the proteins that carry out chemical…
19 January 2012
Science
An inherited mutation in a gene known as the guardian of the genome is likely the link between exploding chromosomes and some particularly aggressive types of cancer, scientists at the European Molecular Biology Laboratory (EMBL), the German Cancer Research Centre (DKFZ) and the University…
12 January 2012
Science
A team of geneticists and computational biologists at the European Molecular Biology Laboratory’s European Bioinformatics Institute (EMBL-EBI), the Wellcome Trust Sanger Institute and Cancer Research UK reveal how an ancient mechanism is involved in gene control and continues to drive genome…
8 January 2012
Science
As an embryo develops, different genes are turned on in different cells, to form muscles, neurons and other bodily parts. Inside each cell’s nucleus, genetic sequences known as enhancers act like remote controls, switching genes on and off. Scientists at the European Molecular Biology Laboratory…
21 July 2011
Science
A fungus that lives at extremely high temperatures could help understand structures within our own cells. Scientists at the European Molecular Biology Laboratory (EMBL) and Heidelberg University, both in Heidelberg, Germany, were the first to sequence and analyse the genome of a heat-loving fungus,…
20 March 2011
Science
Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have developed a new method for studying gene regulation, by employing a jumping gene as an informant. Published online today in Nature Genetics, the new method is called GROMIT. It enables researchers to…
11 March 2011
Science
Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, have developed a new method which enables researchers to label any protein of their choice with any of a wide variety of previously available compounds, in living cells, by introducing a single reactive…
6 March 2011
Science
Scientists at the European Molecular Biology Laboratory (EMBL) and the German Cancer Research Centre (DKFZ), both in Heidelberg, Germany, have developed a new method that uncovers the combined effects of genes. Published online today in Nature Methods, it helps understand how different genes can…
3 February 2011
Science
In our not-so-distant evolutionary past, stress often meant imminent danger, and the risk of blood loss, so part of our body’s stress response is to stock-pile blood-clotting factors. Scientists in the Molecular Medicine Partnership Unit (MMPU), a collaboration between the European Molecular…
2 February 2011
Science
A detailed analysis of data from 185 human genomes sequenced in the course of the 1000 Genomes Project, by scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, in collaboration with researchers at the Wellcome Trust Sanger Institute in Cambridge, UK, as well as the…
16 November 2010
Science
The cells in the different parts of this video are always the same (grey), but, like actors using make-up to highlight different facial features, they have fluorescent labels that mark different cellular components in different colours: blue shows the nucleus, yellow shows tubulin (a component of…
27 October 2010
Science
The 1000 Genomes Project, a major international collaboration to build a detailed map of human genetic variation, has completed its pilot phase. The results are now published in the journal Nature and freely available through the European Molecular Biology Laboratory’s European Bioinformatics…
24 June 2010
Science
Researchers from the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, and the Max-Planck Institute of Immunobiology Freiburg have identified a novel protein complex that regulates around 4000 genes in the fruit fly Drosophila and likely plays an important role in mammals, too.…
31 May 2010
Science
Red blood cells, the delivery men that take oxygen to cells all around the body, have short lives. To keep enough of them in circulation, the human body produces around 2 million of these cells every second – even more in response to challenges like severe blood loss. In a study published today…
2 May 2010
Science
During embryonic development, proteins called Polycomb group complexes turn genes off when and where their activity must not be present, preventing specialised tissues and organs from forming in the wrong places. They also play an important role in processes like stem cell differentiation and…
1 April 2010
Science
Name a human gene, and you’ll find a movie online showing you what happens to cells when it is switched off. This is the resource that researchers at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, and their collaborators in the Mitocheck consortium are making freely…
18 March 2010
Science
Once the human genome was sequenced in 2001, the hunt was on for the genes that make each of us unique. But scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, and Yale and Stanford Universities in the USA, have found that we differ from each other mainly because…
4 March 2010
Science
The thousands of bacteria, fungi and other microbes that live in our gut are essential contributors to our good health. They break down toxins, manufacture some vitamins and essential amino acids, and form a barrier against invaders. A study published today in Nature shows that, at 3.3 million,…
10 December 2009
Science
Is it a boy or a girl? Expecting parents may be accustomed to this question, but contrary to what they may think, the answer doesn’t depend solely on their child’s sex chromosomes. Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany and the Medical Research…
9 July 2008
Science
Genetic recombination, the process by which sexually reproducing organisms shuffle their genetic material when producing germ cells, leads to offspring with a new genetic make-up and influences the course of evolution. In the current issue of Nature, researchers at the European Molecular…
5 February 2008
Science
Much less widely known than the dangerous consequences of iron deficiencies is the fact that too much iron can also cause problems. The exact origin of the genetic iron overload disorder hereditary hemochromatosis [HH] has remained elusive. In a joint effort, researchers from the European Molecular…
22 January 2008
Lab Matters
Drawing on the expertise of multi-disciplinary research teams, the map developed by the 1000 Genomes Project will provide a view of biomedically relevant DNA variations at a resolution unmatched by current resources. The European Bioinformatics Institute (EBI), working with long-term collaborator…
29 June 2007
Science
Hormones control growth, metabolism, reproduction and many other important biological processes. In humans, and all other vertebrates, the chemical signals are produced by specialised brain centres such as the hypothalamus and secreted into the blood stream that distributes them around the body.…
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