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Cancer

Blood pressure drug improves response to cancer therapy

Scientists discovered that antihypertensive agent alters the tissue characteristics of colon cancer metastases. This "stiffness" of metastases has an effect on the therapeutic success.…

By Mathias Jäger

Science

DNA damage and repair jointly leave mutational signatures in the genome.

DNA damage and faulty repair jointly cause mutations

DNA mutations are caused by a combination of DNA damage and repair, shows study by EMBL-EBI and collaborators.…

By Mehdi Khadraoui

Science

Understanding brain tumours in children

The causes of 40 percent of all cases of certain medulloblastoma – dangerous brain tumours affecting children – are hereditary. These are the findings of a recent genetic analysis carried out by scientists from EMBL and numerous colleagues around the world.…

By Mathias Jäger

Science

The Pan-Cancer project

EMBL co-leads most comprehensive study of genetic causes of cancer…

By Mathias Jäger

Science

Protecting data in the cloud

Cloud computing offers unprecedented opportunities for global-scale research collaborations. It also presents a unique set of challenges in terms of data protection and the ethics of data sharing.…

By Cella Carr

Science

Characterising RNA alterations in cancer

The largest and most comprehensive catalogue of cancer-specific RNA alterations reveals new insights into the cancer genome.…

By Vicky Hatch

Science

Cancer mutations occur decades before diagnosis

Researchers at EMBL’s European Bioinformatics Institute (EMBL-EBI) and the Francis Crick Institute have analysed the whole genomes of over 2600 tumours from 38 different cancer types to determine the chronology of genomic changes during cancer development.…

By Vicky Hatch

Science

Studying DNA rearrangement to understand cancer

Using the dataset from the Pan-Cancer project, scientists has developed methods to group, classify, and describe large rearrangements of the genome that are a key driver of cancer.…

By Fabian Oswald

Science

Chromothripsis in human cancer

Researchers at Harvard Medical School and EMBL-EBI have carried out the largest analysis across cancer types of the newly discovered mutational phenomenon chromothripsis.…

By Vicky Hatch

Science

Finding genetic cancer risks

Using the data from the Pan-Cancer project EMBL scientists describe how our genetic background influences cancer development.…

By Fabian Oswald

Science

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