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22 November 2024

Celebrating 25 years of EMBL Rome

Lab Matters EMBL Rome celebrates its 25th anniversary this year – some impressions of the symposium and party organised for staff and alumni to mark this special occasion.

2024

lab-matters

16 October 2024

All eyes on science!

Lab Matters EMBL Rome volunteers participated in the European Researchers’ Night organised by the CNR in Montelibretti, attended by over 1,500 visitors. They prepared activities and games reflecting the wide variety of projects conducted at the site and across EMBL.

2024

lab-matters

10 July 2024

Leveraging expertise across EMBL services

Connections A scientific workshop on flow cytometry was organised at EMBL Rome, taking advantage of the presence of the Advanced Mobile Laboratory, the biggest unit of EMBL’s mobile lab fleet.

2024

connections

17 June 2024

TREC in Italy – sampling from coast to coast

Connections For almost two months, Italy was the stage for the TREC expedition, with a rich programme of events organised across the country attended by the public, scientists, schools, and high-level political stakeholders, including Minister of University and Research Anna Maria Bernini.

2024

connections

9 May 2024

An epigenome editing toolkit to dissect the mechanisms of gene regulation

Science & Technology A study from the Hackett group at EMBL Rome led to the development of an epigenetic editing system that allows to precisely program chromatin modifications at any specific position in the genome, to understand their causal role in transcription regulation.

2024

science-technology

1 May 2024 Alt Text: An artistic representation of gut microbes and sperm cells

Father’s gut microbes affect the next generation

Science & Technology Scientists from EMBL Rome and EMBL Heidelberg found that disrupting the gut microbiome of male mice increases the risk of disease in their offspring. Their findings suggest that a father’s pre-conception environment can have lifelong effects on offspring.

2024

science-technology

16 November 2023

New evidence on retinal function

Science & Technology A new study from the Asari group at EMBL Rome shows a different retinal function in awake mice compared to isolated retinal samples. These new insights could help to develop prosthetic devices that can act as a retina in the future.

2023

sciencescience-technology

9 October 2023

A night to share the wonders of science 

Lab Matters EMBL Rome celebrated the European Researchers’ Night by participating in an event organised at the CNR Campus in Montelibretti.

2023

lab-matters

26 July 2023 Participants listen to the trainer in front of a screen displaying a microscopy image

Imaging-based spatial-omics: EMBO Practical Course at EMBL Rome 

Lab MattersScience & Technology The first EMBO Practical Course on imaging-based spatial-omics was organised at EMBL Rome to explore the latest techniques to visualise RNA transcripts and proteins in their native tissues.

2023

lab-mattersscience-technology

28 June 2023 Female scientist in white lab coat enjoying camaraderie of colleagues.

After EMBL: Urtė Neniškytė

People & Perspectives EMBL Rome alumna Urtė Neniškytė returned to her native Lithuania, helping establish the Vilnius University-EMBL Partnership Institute and advance genome-editing technologies there.

2023

alumnipeople-perspectives

30 March 2023 Profile picture of Cornelius Gross, interim head of EMBL Rome

ERC Advanced Grant awarded to EMBL Rome researcher

EMBL AnnouncementsLab Matters Interim head of EMBL Rome Cornelius Gross has been awarded an Advanced grant from the European Research Council (ERC) for his project TERRITORY, aimed at investigating the neural basis of territorial aggression and fear.

2023

embl-announcementslab-matters

31 January 2023

ERC Consolidator Grant success at EMBL

EMBL AnnouncementsLab Matters EMBL Rome group leader Jamie Hackett receives EUR 2 million for the ModLogic project, aimed at understanding how chromatin modifications impact gene activity.

2023

embl-announcementslab-matters

1 June 2022

EMBL in Italy event held at GSK Vaccines in Siena

Connections The GSK Vaccines site in Siena hosted the annual EMBL in Italy event. The hybrid meeting brought together industry leaders, representatives from biotech start-ups, data scientists, and researchers from academia.

2022

alumniconnections

12 April 2022

EMBL consolidates ties with Sapienza University

ConnectionsLab Matters EMBL and the Sapienza University of Rome confirm their reciprocal interest in intensifying collaborations and launch new opportunities for exchange of expertise

2022

connectionslab-matters

8 April 2022 a metaphor for the process of epigenetic inheritance

A metaphor for epigenetic inheritance

Science & Technology Recent studies from the Hackett group at EMBL Rome have revealed new insights on the mechanism regulating transmission of non-genetic information during embryonic development, and inspired a scientific illustration

2022

sciencescience-technology

22 October 2021 Oblong shape with two holes and coloured dots inside, representing phytoplankton cells and nitrogen-fixing bacteria

Analysis and sorting with flow cytometry

Lab MattersScience & Technology A technology around since the ‘60s, flow cytometry has increasing applications. New leadership at EMBL’s flow cytometry facilities is looking to ease use, expand training, and encourage more collaboration.

2021

lab-mattersscience-technology

17 September 2021 Artistic representation of the complex cell circuit forming the retina

Vision unveiled: new roles for the retina in visual processing

Science & Technology EMBL scientists have found evidence of an unexpected role for retinal cells in pre-processing visual information; their results provide potential opportunity for future prosthetic visual aids.

2021

research-highlightssciencescience-technology

8 June 2021 Two scientists in lab coats working on an instrument in the lab.

EMBL external research community survey

Lab Matters EMBL is conducting an Impact Assessment of our experimental services to understand the value these services have for our external user community. If you have accessed EMBL experimental services at one or more of our facilities to support the conduct of your research, we would like to hear from you.

2021

lab-matters

8 June 2021 Purple, blue and yellow dots on a black background.

Dream team

Science & Technology At EMBL, we have many dream teams – groups of individuals who support each other, innovate, and work together. One of those dream teams bridges two core facilities at EMBL Rome.

2021

picture-of-the-weekscience-technology

28 April 2021 Artistic representation of brain and DNA

Uniting strengths to expand research

ConnectionsLab Matters The European Molecular Biology Laboratory and the Italian Institute of Technology have signed an agreement to expand the scope of their collaboration to include areas of mutual interest and in the context of EMBL’s 2022-2026 Programme “Molecules to Ecosystems”.

2021

connectionslab-matters

30 March 2021 Ana Boskovic sitting in her office

Welcome: Ana Boskovic

Lab MattersPeople & Perspectives The new group leader at EMBL Rome will study how embryos can inherit non-genetic information from their parents that causes stable and heritable effects

2021

lab-matterspeople-perspectives

16 March 2021 Pink blooming tree in front of functional building.

Italian Spring

Lab Matters EMBL’s site in Monterotondo has recently been blessed with blue skies and sunshine, leading to trees blooming early on campus.

2021

lab-matterspicture-of-the-week

29 January 2021 Flags of EMBL, Italy and CNR

Strengthening collaborations in Italy

ConnectionsLab Matters EMBL and CNR have signed a memorandum of understanding to strengthen scientific cooperation. The agreement will foster collaborative projects and integrate them within the European and global scientific landscape.

2021

connectionslab-matters

28 October 2020 A brain hovers over a chess board, lines flow from the hypothalamus to the pieces, symbolising control over reactions to an aggressor and territory.

Should I run, or should I not? The neural basis of aggression and flight

Science & Technology Researchers in the Gross group at EMBL Rome have investigated the mechanism behind defensive behaviour in mice. They have identified a specific area of the brain that encodes both spatial and threat cues to drive location-specific defensive responses.

2020

sciencescience-technology

8 October 2020 Alvaro Crevenna, heads EMBL Rome’s Microscopy Facility. Credit: EMBL

Beyond the lens – microscopy at EMBL Rome

Lab MattersScience & Technology Research facilities play a crucial role in the advancement of science by supporting scientists with specialised expertise and state-of-the-art equipment. The Microscopy Facility at EMBL Rome exemplifies this role by making a wide variety of light microscopy technologies available to its researchers…

2020

lab-mattersscience-technology

7 August 2020 Black and white photo of Phil Avner sitting in his office and looking at his smartphone. a large stack of papers on his desk

Arrivederci Phil!

Lab MattersPeople & Perspectives As he enters retirement, Head of EMBL Rome Phil Avner reflects on his scientific career and memories from his time as Head of EMBL’s site in Italy

2020

lab-matterspeople-perspectives

2 July 2020 epigenetic reprogramming, epigenetic memory, Hackett group

Unravelling epigenetic reprogramming

Science & Technology A study conducted by the Hackett group at EMBL Rome has identified key factors controlling the complex system of gene regulation during early embryo development, shedding new light on the mechanisms behind these events and on their evolutionary implications. Their findings are published in Nature…

2020

sciencescience-technology

29 June 2020 Gene Editing and Embryology Facility at EMBL Rome

Editing the mouse genome to study SARS-CoV-2 infection

Science & Technology To study how SARS-CoV-2 infects cells, the Gene Editing and Embryology Facility (GEEF) at EMBL Rome will generate mice that express a human version of a protein called ACE2. The mouse line will be shared with preclinical research collaborators carrying out vaccine and antibody trials, and with the…

2020

sciencescience-technology

25 June 2020 Scientists in the Hackett group at EMBL Rome doing lab work

Silencing the SARS-CoV-2 receptor with epigenetic modifications

Science & Technology EMBL scientists develop a new molecular tool to prevent SARS-CoV-2 infection in mice. This tool is able to cause targeted epigenetic modifications of specific genes in specific cell populations. They will use it in mice to target airway cells that express the ACE2 protein – the receptor that…

2020

sciencescience-technology

4 February 2020

From cosmetics to blood cells

Science & Technology Morgan Oatley and her colleagues in Christophe Lancrin’s group investigated how haematopoietic stem cells emerge from the endothelium in developing mouse embryos.

2020

picture-of-the-weekscience-technology

29 November 2019 Choanocyte chamber of sponge, with neuroid cell

Neural pathways

Science & Technology Exploring the diverse routes by which EMBL scientists are driving forward neurobiology

2019

sciencescience-technology

5 November 2019

A mix of sensations

Science & Technology Traditionally, we talk about having five senses: sight, hearing, taste, smell and touch. In reality, our bodies are capable of much more. Sitting right under our skin are a variety of sensory neurons, which are specialised in detecting light touch, pain, temperature, itch or the body’s position.…

2019

picture-of-the-weekscience-technology

30 October 2019

Fallingwater filled with mice

People & Perspectives Nadia Rosenthal describes how she built EMBL Rome’s mouse house

2019

alumnipeople-perspectives

12 September 2019 Tara stopover in Rome

EMBL and Tara: Rome

EMBL Announcements The next stop on Tara’s journey will be at the mouth of the Tiber

2019

embl-announcementsevents

26 August 2019

From rodents to roadsters

People & Perspectives Klaus Rajewsky recalls the pioneering spirit of EMBL Rome’s first years

2019

alumnipeople-perspectives

9 July 2019 A model of CRISPR/Cas9

Wielding the genetic scissors

Science & Technology What CRISPR may bring for the future of biology, and how it is used at EMBL

2019

sciencescience-technology

28 June 2019 EIPOD4 logo banner showing the 4 available tracks, research, industrial, clinical and academic.

EIPOD4: 2019 applications are open

EMBL AnnouncementsLab Matters EIPOD4 will prepare researchers for the increasing interdisciplinarity of scientific career paths

2019

embl-announcementslab-matters

18 March 2019 A smiling Santiago Rompani, new group leader at EMBL Rome, stands in front of a vine covered wall

Welcome: Santiago Rompani

People & Perspectives New EMBL group leader explores what neurobiology can teach us about what it means to be human

2019

people-perspectivesscience

17 December 2018 Mouse skin samples of the rare genetic skin disease amyloidosis, before light treatment (left) and after treatment (right). The arrows indicate aggregates of debris, which cause the skin to become rough and uncomfortable. Upon treatment these aggregates are reduced, allowing the skin to heal. IMAGES: Paul Heppenstall and Linda Nocchi / EMBL

Using light to stop itch

Science & Technology EMBL researchers have found a way to stop itch with light in mice

2018

sciencescience-technology

7 August 2018 Group picture of the students and coordinators of the second edition of ‘Summer in Science’ at EMBL Rome. PHOTO: Berta Carreño/EMBL

Summer in Science 2018

Lab Matters EMBL Rome opens its labs for students to get their first real taste of science

2018

eventslab-matters

2 August 2018 Humans of EMBL: Outreach

Humans of EMBL: Outreach

Lab MattersPeople & Perspectives Discover how EMBLers across all sites share their passion for science

2018

lab-matterspeople-perspectives

19 June 2018 Kristina Havas-Cavalletti

EMBL in Italy: Kristina Havas-Cavalletti

People & Perspectives More than 80 attendees gathered at the EMBL in Italy event at the FIRC Institute of Molecular Oncology (IFOM) in Milan

2018

alumnipeople-perspectives

24 April 2018

Managing chronic pain with light

Science & Technology Scientists at EMBL Rome develop new method that uses light to manage neuropathic pain in mice

2018

sciencescience-technology

20 March 2018 A heatmap graph displaying high (red) or low (blue) levels of gene expressions in different cells.

From blood vessels to blood stem cells

Science & Technology EMBL scientists discover how blood vessel cells become blood stem cells during embryonic development

2018

sciencescience-technology

23 February 2018 Meet some of the Humans of EMBL

Humans of EMBL: Past lives

Lab MattersPeople & Perspectives Discover the past lives and journeys that brought people to EMBL

2018

lab-matterspeople-perspectives

15 January 2018 This mouse ovary and these immature eggs (in blue), can be used to study patterns of DNA methylation that affect only females.

Welcome: Matthieu Boulard

People & Perspectives New EMBL group leader investigates the mystery of heritable gene silencing

2018

people-perspectivesscience

21 December 2017

Your favourite reads of 2017

Lab Matters A look back at some of the most read stories on EMBL’s news website this year

2017

lab-matters

29 November 2017 Collage of photos of some humans of EMBL discussed in this article

Humans of EMBL: Curiosity

Lab Matters EMBLers across all sites share how their curiosity about the world shapes their everyday life

2017

lab-matters

11 July 2017

New name for EMBL’s site in Italy

EMBL AnnouncementsLab Matters EMBL’s unit in Italy changes name to better reflect new research focuses and highlight its location

2017

embl-announcementslab-matters

13 June 2017

Senses: Fathoming fear

Science & Technology EMBL’s Cornelius Gross wants to understand fear responses and the brain circuitry that governs them

2017

sciencescience-technology

31 May 2017

Senses: What you see is how you feel

Science & Technology EMBL’s Hiroki Asari investigates how our internal state can change the way our eyes work

2017

sciencescience-technology

24 May 2017

Humans of EMBL: Senses

Lab MattersPeople & Perspectives People across EMBL’s sites reflect on the ways they perceive their world

2017

lab-matterspeople-perspectives

5 May 2017

Welcome: Jamie Hackett

People & Perspectives Meet Monterotondo’s new group leader for epigenetic reprogramming and inheritance, Jamie Hackett

2017

people-perspectivesscience

25 April 2017

Embryos use ancient viral DNA

Science & Technology EMBL scientists detect important function of genetic sequence our ancestors assimilated from a virus

2017

sciencescience-technology

11 April 2017

Experience life in the lab!

Lab Matters Call for applications for school students to join ‘Summer in Science’ in Monterotondo

2017

lab-matters

13 December 2016

Study offers approach to treating pain

Science & Technology Research on the effect of nerve cell stiffness on sensitivity to touch could lead to new painkillers

2016

sciencescience-technology

27 October 2016

Welcome to EMBL: Robert Prevedel

People & Perspectives Robert Prevedel develops deep-tissue microscopy for scientists to peer deep inside living organisms

2016

people-perspectivesscience

30 August 2016 Francesco Iorio, an EMBL-EBI/Sanger Interdisciplinary Postdoc and now a senior bioinformatician at EMBL-EBI, strives to be "a great dad, as well as a great researcher". PHOTO: Robert Slowley

Postdocs of EMBL

Lab MattersPeople & Perspectives Turning the spotlight on the diverse universe of EMBL’s 200-strong postdoc community

2016

lab-matterspeople-perspectives

27 May 2016 Italy-based alumni gathered for the ‘EMBL in Italy’ event on 27 May to learn about the focus of researchers at EMBL’s Monterotondo site. PHOTO: EMBL/Isabelle Kling

Italian interconnections

Connections Marco Tripoldi and Valeria Carola join colleagues and peers at gathering of Italy-based alumni

2016

alumniconnections

9 May 2016 Kikusui spent 10 days this March in the Gross lab at EMBL brainstorming the neural mechanisms of social behaviour. PHOTO: Cornelius Gross

The pheromones behind romance

Science & Technology A perfect match: behaviourist Takefumi Kikusui visits the Gross group to explore animal attraction

2016

sciencescience-technology

7 April 2016

Welcome: Hiroki Asari

People & Perspectives Why does a cookie look different depending on how hungry you are? Neuroscientist Asari wants to find out

2016

people-perspectivesscience

18 March 2016

Forgetting to learn

Science & Technology Neural mechanisms in mouse brains indicate that we actively forget as we learn

2016

sciencescience-technology

17 December 2015

What’s on in 2016

Connections With 28 conferences and 57 courses, 2016 will be EMBL’s most eventful year to date.

2015

connectionsevents

25 November 2015

Humans of EMBL

Lab MattersPeople & Perspectives Compelling short stories that shine light on the life and work of EMBL staff.

2015

lab-matterspeople-perspectives

24 August 2015

Cellular synergy

People & Perspectives Alumnus Thomas Vaccari reflects on the first joint symposium with EMBL Monterotondo, in Milan.

2015

eventspeople-perspectives

24 August 2015 Maria Kamper at the her desk.

Pathways: Culture of care

ConnectionsLab Matters Maria Kamber, who heads the mouse facility, ensures “dignity, compassion and respect” for her charges.

2015

connectionslab-matters

13 July 2015

EIPOD goes cubic

EMBL AnnouncementsLab Matters EI3POD: flagship interdisciplinary postdoc programme opens its doors to academia and industry.

2015

embl-announcementslab-matters

16 February 2015

Fight or flight?

EMBL Insight Lecture – Why do we do what we do? – now available to view online.

2015

events

26 January 2015 ILLUSTRATION: AAD GOUDAPPEL

Cell control in a flash

Science & Technology From using light to control brain activity to illuminating fruit fly development and mice’s sense of touch

2015

sciencescience-technology

9 December 2014 A bundle of nerves that relays information from touch receptors on the skin to the spinal cord and ultimately the brain, imaged with the new technique. IMAGE: EMBL/L.CASTALDI

Delighting in detail

Science & Technology Unprecedented detail in images of mouse neurons thanks to new SNAP-tagging microscopy technique.

2014

sciencescience-technology

22 October 2014

Protecting us from our cells

Science & Technology Growth factor IGF-1 boosts natural defence against type-1 diabetes and multiple sclerosis

2014

sciencescience-technology

8 July 2014 Head of EMBL Monterotondo, Philip Avner, makes a toast.

Buon Compleanno!

Lab Matters EMBL Monterotondo celebrates double anniversary with fun, fireworks, festa and familiar faces

2014

alumnilab-matters

1 July 2014 Vasily Sysoev

Back to school

Lab Matters School ambassadors show next generation that scientists are more ‘role model’ than ‘mad professor’

2014

lab-matters

1 July 2014 Illustration: Aad Goudappel, Rotterdam

Five for the future

Lab Matters Scientists from EMBL's five sites reflect on the opportunities and challenges that might lie ahead

2014

lab-matters

2 February 2014

Making your brain social

Science & Technology In many people with autism and other neurodevelopmental disorders, different parts of the brain don’t talk to each other very well. Scientists have now identified, for the first time, a way in which this decreased functional connectivity can come about. In a study published online today…

2014

sciencescience-technology

21 July 2011 Microglia (green) in a mouse brain. The nuclei of all cells in the brain are labelled blue. Credit: EMBL/ R.Paolicelli

Gardening in the brain

Science & Technology Gardeners know that some trees require regular pruning: some of their branches have to be cut so that others can grow stronger. The same is true of the developing brain: cells called microglia prune the connections between neurons, shaping how the brain is wired, scientists at the European…

2011

sciencescience-technology

25 August 2010

Freeze or run? Not that simple

Science & Technology Fear can make you run, it can make you fight, and it can glue you to the spot. Scientists at the European Molecular Biology Laboratory (EMBL) in Monterotondo, Italy and GlaxoSmithKline in Verona, Italy, have identified not only the part of the brain but the specific type of neurons that determine…

2010

sciencescience-technology

10 December 2009 These microscopy images demonstrate the effects of Notch signalling on the hearts of newborn mice (top) and of adult mice after a heart attack (bottom). In a normal neonatal heart (top left), the two major heart chambers (ventricles) are clearly separated by tissue (septum). But when Notch signalling was inactivated in an embryo’s heart muscle cells, the septum between the ventricles of the newborn mouse’s heart was incomplete (asterisk). The same defect commonly occurs in humans with congenital heart disease, often leading to circulatory distress. In the images of adult hearts (bottom), healthy tissue is shown in red and damaged tissue in blue. Normally (bottom left), a heart attack causes extensive tissue damage to the left ventricle (right-hand cavity), but mice in which Notch was re-activated after the heart attack had reduced tissue damage (bottom right) and improved cardiac function. Image credit: EMBL

From fruit fly wings to heart failure. Why Not(ch)?

Science & Technology Almost a century after it was discovered in fruit flies with notches in their wings, the Notch signalling pathway may come to play an important role in the recovery from heart attacks. In a study published today in Circulation Research, scientists at the European Molecular Biology Laboratory (EMBL)…

2009

sciencescience-technology

21 September 2009 This microscopy image, taken ten days after injury, shows that the muscle fibres of normal mice (left) had re-grown, while in mice which couldn’t boost C/EBPβ production (right) there were still many fibres that had not regenerated (arrowheads), and the tissue had a number of scars (arrows).

To regenerate muscle, cellular garbage men must become builders

Science & Technology For scientists at the European Molecular Biology Laboratory (EMBL) in Monterotondo, Italy, what seemed like a disappointing result turned out to be an important discovery. Their findings, published online this week in the journal Proceedings of the National Academy of Sciences (PNAS), provide…

2009

sciencescience-technology

22 June 2009 EMBL Rome

European centre of excellence for mouse biology celebrates its 10th anniversary

Lab Matters Mice are one of biology’s most important model organisms, because 98% of their genes and many of their traits and diseases are similar to ours. Researchers at the Mouse Biology Unit of the European Molecular Biology Laboratory (EMBL) take advantage of these similarities and use mice to study…

2009

lab-matters

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