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Rome

epigenetic reprogramming, epigenetic memory, Hackett group

Unravelling epigenetic reprogramming

A study conducted by the Hackett group at EMBL Rome has identified key factors controlling the complex system of gene regulation during early embryo development, shedding new light on the mechanisms behind these events and on their evolutionary implications. Their findings are published in Nature…

By Rossana De Lorenzi

Science

Gene Editing and Embryology Facility at EMBL Rome

Editing the mouse genome to study SARS-CoV-2 infection

To study how SARS-CoV-2 infects cells, the Gene Editing and Embryology Facility (GEEF) at EMBL Rome will generate mice that express a human version of a protein called ACE2. The mouse line will be shared with preclinical research collaborators carrying out vaccine and antibody trials, and with the…

By Rossana De Lorenzi

Science

Scientists in the Hackett group at EMBL Rome doing lab work

Silencing the SARS-CoV-2 receptor with epigenetic modifications

EMBL scientists develop a new molecular tool to prevent SARS-CoV-2 infection in mice. This tool is able to cause targeted epigenetic modifications of specific genes in specific cell populations. They will use it in mice to target airway cells that express the ACE2 protein – the receptor that…

By Rossana De Lorenzi

Science

New insights into epigenetic modifications

Scientists at EMBL Rome unveil the mechanism behind the most studied epigenetic modification.…

By Rossana De Lorenzi

Science

From cosmetics to blood cells

Morgan Oatley and her colleagues in Christophe Lancrin’s group investigated how haematopoietic stem cells emerge from the endothelium in developing mouse embryos.…

By Mathias Jäger

Picture of the week

Choanocyte chamber of sponge, with neuroid cell

Neural pathways

Exploring the diverse routes by which EMBL scientists are driving forward neurobiology…

By Cella Carr

Science

A mix of sensations

Traditionally, we talk about having five senses: sight, hearing, taste, smell and touch. In reality, our bodies are capable of much more. Sitting right under our skin are a variety of sensory neurons, which are specialised in detecting light touch, pain, temperature, itch or the body’s position.…

By Doreen Feike

Picture of the week

Fallingwater filled with mice

Nadia Rosenthal describes how she built EMBL Rome’s mouse house…

By Guest author(s)

Alumni

Tara in Barcelona

Snapshots from Mission Microplastics

Highlights from the Tara stopovers in Rome, Marseille, and Barcelona…

By Cella Carr

Events

Tara stopover in Rome

EMBL and Tara: Rome

The next stop on Tara’s journey will be at the mouth of the Tiber…

By Fabian Oswald

Events

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