Electron Microscopy

Laboratory Officer Nicole Schieber working in EMBL's Electron Microscopy Core Facility. PHOTO: Viola Oorschot/EMBL

Taking a closer look at infected cells to better understand COVID-19

EMBL electron microscopy specialists collaborate with researchers from Heidelberg University Hospital to understand the changes occurring in cell structures upon SARS-CoV-2 infection.

By Anne-Marie Alleaume


Super-resolution image of the basal surface of a cellularising Drosophila embryo.

Actin crosslinking plays key role in tissue morphogenesis

New insights into mechanisms behind embryonic development

By Cella Carr


An example virtual map of individual leukaemia cells on a resin section, detected automatically using SerialEM and py-EM.

Breaking the bottleneck in imaging data collection

Scientists develop software tools for automated acquisition of electron microscopy data

By Cella Carr


An 88% complete model of human hemoglobin (PDB id 5ni1) built de novo by ARP/wARP into a 3.2 Å cryo-EM map. IMAGE: Victor Lamzin/EMBL

ARP/wARP 8.0 released

Researchers at EMBL Hamburg have released the next generation of their ARP/wARP software

By Berta Carreño

Lab Matters

Optogenetics has successfully been used in a diverse range of organisms.

EMBL’s first wetlab e-learning courses go live

EMBL’s training programme launches its first e-learning courses: introductions to optogenetics and CLEM

By Berta Carreño


With help from an external transcription factor (lavender, peach, and green), Pol III (grey) and its built-in transcription factor (yellow), create a cage around a cell’s DNA (plum). IMAGE: EMBL/Matthias Vorländer

Pol III enzyme grips DNA and begins reading fast

EMBL researchers uncover how a key enzyme that helps cells make new proteins starts its work

By Sarah B. Puschmann


Schematic reconstruction of the Robo1 structure. IMAGE: Andrew McCarthy / Structure

One way crossing across the midline

EMBL researchers solve a decades-long debate on a key process for brain and embryo-development

By Berta Carreño


In this representation of influenza polymerase, a molecule (white) that strongly inhibits the enzyme’s activity is shown bound to the region of the enzyme (red) that usually binds the cap section of mRNA. IMAGE: EMBL/Cusack Group

Futures: Unravelling influenza

ERC grantee Stephen Cusack shares his vision for the next ten years

By Edward Dadswell


Alasdair McDowall (left), an EMBL research technician 1978-1987, and Jacques Dubochet (right), EMBL group leader 1978-1987, together in Heidelberg

Alasdair McDowall’s slow road to flash freezing

How a research technician with a master’s degree contributed to Nobel Prize-winning work

By Sarah B. Puschmann


An artist’s representation of the shrinking holes and expanding pores that form in the nuclear membrane of cells during mitosis

Cells grow pores from shrinking holes

New research shows how pores form in the membrane that surrounds a cell’s nucleus

By Sarah B. Puschmann



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