Shedding light on rare diseases: open data and model organisms
Perspectives, Science Why open data from model organisms is essential for rare disease research.
2023
perspectivesscience
Molecules to Ecosystems: Jo McEntyre on data services
Lab Matters, Perspectives Jo McEntyre talks about data services, open data and a new era for research assessment.
2023
lab-mattersperspectives
Case study: AlphaFold uses open data and AI to discover the 3D protein universe
Perspectives, Science Open data played a pivotal role in the development of the AlphaFold AI. The same open principles now apply to AlphaFold predictions.
2023
perspectivesscience
Ensembl 109 has been released
Updates from data resources Latest Ensembl and Ensembl Genomes releases bring updates to donkey and horse assemblies, and lots of new plants and metazoa.
2023
updates-from-data-resources
PDCM Finder – an open global cancer research platform for patient-derived cancer models
Updates from data resources Aggregating clinical, genomic and functional data from patient-derived xenografts, organoids and cell lines
2023
updates-from-data-resources
EMBL-EBI databases considered critical to life sciences
Announcements, Science Open data resources that enable global research and development recognised by the Global Biodata Coalition.
2022
announcementsscience
EMBL-EBI appoints new Head of Technical Services
Announcements Andy Cafferkey takes on strategic role to help the institute respond to increasing demands from the global life science community.
2022
announcements
Genomic Data Infrastructure – integrating genomics into healthcare
Announcements, Science EMBL-EBI supports new European Commission project set to support the use of genomics in research and healthcare.
2022
announcementsscience
New releases: InterPro 91.0 and InterProScan 5.59-91.0
Updates from data resources We are pleased to announce the release of InterPro 91.0 and InterProScan 5.59-91.0
2022
updates-from-data-resources
European institutes commit to data access across borders
Announcements, Science The Federated EGA is set to improve access to sensitive human data in a safe and secure way.
2022
announcementsscience
AlphaFold: where will the next AI breakthrough come from?
Perspectives, Science Ewan Birney, Deputy Director General of EMBL and Director of EMBL-EBI, reveals the key factors that enabled AlphaFold to change the world of biology.
2022
perspectivesscience
New releases: InterPro 90.0 and InterProScan 5.57-90.0
Updates from data resources InterPro version 90.0 and InterProScan 5.57-90.0 are now available. InterPro now features hundreds of new methods integrated from partner databases, and InterProScan draws on over 40000 entries
2022
updates-from-data-resources
UKRI allocates funding for EMBL-EBI data resources
Announcements Funding set to support data resources for key areas of antimicrobial resistance, sustainable agriculture and biodiversity loss
2022
announcements
The MANE collaboration: working together to support genome science
Research highlights, Science Researchers from the MANE collaboration bring you the most comprehensive human genome annotation dataset to date.
2022
research-highlightsscience
Genomic sequencing aids the global Tuberculosis fight
Perspectives, Science Zamin Iqbal and his team are working with researchers all over the globe to help put a stop to Tuberculosis
2022
perspectivesscience
Deep learning models help predict protein function
Perspectives, Science Deep learning models can improve protein annotations and has helped expand the Pfam database.
2022
perspectivesscience
Connecting the dots between bacterial genes around the world
Science Bork Group at EMBL Heidelberg analysed a new global gene database to study how genes emerge and spread across various habitats on our planet. In the future, the group will expand the database and use it for studying microbial gene evolution and dispersal at a finer-grained scale.
2021
science
Addressing the biodiversity crisis with 12,000 reptiles – or one database
Alumni An alumnus reflects on the reptile database he started in 1996 while at EMBL. The database helps understand biodiversity issues.
2021
alumni
DUO: streamlining access to biomedical datasets
Science The GA4GH Data Use Ontology (DUO) supports a data authorisation and access framework to streamline consent to use biomedical data
2021
science
Open data on the rise: the value of EMBL-EBI data resources
Lab Matters Independent study reveals that EMBL-EBI open data resources are critical for the life sciences.
2021
lab-matters
Harnessing the microbiome to improve meat production
Science International project uses biomolecular data to improve animal feed and make meat production more sustainable
2021
science
BY-COVID – a new EU project for pandemic preparedness
Science The BY-COVID project aims to make infectious disease data, including COVID-19, openly available to everyone.
2021
science
CRyPTIC: cataloguing drug resistance mutations in M. tuberculosis
Science Profiling M. tuberculosis strains from 27 countries to reveal causes of drug resistance.
2021
science
3D-Beacons Network: protein structure data, all in one place
Science 3D-Beacons Network acts as a one-stop shop for protein structures by combining and standardising data from several providers.
2021
science
DeepMind and EMBL release the most complete database of predicted 3D structures of human proteins
Science Partners use AlphaFold, the AI system recognised last year as a solution to the protein structure prediction problem, to release more than 350,000 protein structure predictions including the entire human proteome to the scientific community.
2021
science
Accessible 3D protein models to accelerate scientific discovery
Science DeepMind and EMBL-EBI to make millions of protein structure predictions freely available to the scientific community.
2021
science
Great expectations – the potential impacts of AlphaFold DB
Science A discussion of the applications that AlphaFold DB may enable and the possible impact of the resource on science and society.
2021
science
Visualising RNA structures using R2DT
Science New software enables scientists to visualise RNA secondary structures using the world’s largest RNA structure dataset.
2021
science
Unparalleled inventory of the human gut ecosystem
Science An international team of scientists has collated all known bacterial genomes from the human gut microbiome into a single large database. Their work will allow researchers to explore the links between bacterial genes and proteins, and their effects on human health.
2020
science
Helping researchers identify host proteins used by coronavirus
Science EMBL scientists working in the groups of Matthias Hentze and Wolfgang Huber have created RBPbase – a database of RNA-binding proteins – to assist the identification of proteins that interact with the SARS-CoV-2 RNA genome.
2020
science
EMBL-EBI launches COVID-19 Data Portal
Science The new collaborative space will help scientists, public health and healthcare professionals around the world to fight the coronavirus pandemic.
2020
science
EMBL-EBI leads International collaboration to share COVID-19 research data
Science EMBL-EBI set to launch European COVID-19 Data Platform to help store, share, and analyse research data linked to the COVID-19 pandemic.
2020
science
Pinpointing rare disease mutations
Science New resource that categorises genes essential for supporting life could be used to identify rare disease mutations
2020
science
Machine learning finds critical phosphosites
Science Resource has implications for disease research
2019
science
Microbiomes take the stage at New Scientist Live
Events On microbiomes, public engagement and not being boring
2019
events
A new home for biological images
Science The BioImage Archive - EMBL-EBI's first dedicated imaging data resource
2019
science
Sex and diet affect proteotype
Science EMBL scientists have discovered that the proteome is substantially affected by both sex and diet
2019
science
Welcome: Jessica Vamathevan
Lab Matters Building bonds between academia and industry
2019
lab-matters
Comprehensive protein data for drug development
Lab Matters PDBe-KB - new data resource for protein structure and function launches
2019
lab-matters
More than 100 new gut bacteria discovered in human microbiome
Science A new database of bacteria in the human microbiome is the most comprehensive to date.
2019
science
Funding for bioinformatics technical infrastructure
Lab Matters Enhancing the world's bioinformatics infrastructure
2019
lab-matters
Algorithm identifies gene–environment relationships
Science New algorithm will enhance understanding of relationship between genotype and environmental factors
2018
science
Welcome: Sarah Butcher
Lab Matters Building bridges between scientists and software developers
2018
lab-matters
Sanofi joins Open Targets
Lab Matters Pharmaceutical company Sanofi strengthens drug targets discovery collaboration Open Targets
2018
lab-matters
Europe PMC now indexes preprints
Science Europe PMC adds preprints to its search
2018
science
BioModels performance boost, new model formats
Science New BioModels infrastructure supports significantly more model formats and offers improved search
2017
science
Opinion: Archives for Science
Lab Matters Biologists Sydney Brenner and Richard J. Roberts addressed the importance of scientific archives
2017
lab-matters
Welcome: Zamin Iqbal
Science The Iqbal research group hopes to build a 'Google of bacteria' to help better interpret the genome
2017
science
The sexual dimorphism dilemma
Science IMPC explains how much the sex of animals is misdirecting research results
2017
science
Omnipath for signalling pathways
Science New method combines signalling pathway data resources to improve systems biology research
2016
science
Form follows function
Science 'The PDB plays a crucial role in structural biology research and development'
2016
science
Supporting the bioimaging revolution
Science Commentary in Nature Methods introduces the EMPIAR resource and gives glimpse of future developments
2016
science
What is the value of open data?
Lab Matters Independent analysis of EMBL-EBI underscores the value and impact of open data in the life sciences
2016
lab-matters
Event gets to the core of research
Events Find out what’s in store at the 2016 Core Technologies for the Life Sciences meeting.
2015
events
Enzyme research made easier
Science Enzyme Portal makes it easier to explore all enzyme-related data in EMBL-EBI’s public resources.
2015
science
From side-project to valuable resource
Lab Matters Introducing the Small Angle Scattering Biological Data Bank, developed at EMBL Hamburg.
2015
lab-matters
The genome in the cloud
Science Jan Korbel and colleagues publish commentary on risks and rewards of genome cloud computing.
2015
science
EMBL-EBI joins CERN openlab
Lab Matters CERN openlab enters a new phase, expanding to include EMBL-EBI and other public research organisations.
2015
lab-matters
Why you need an ORCID
Lab Matters Jenny Cham blogs about how ORCID helps distinguish her from all the other Jenny Chams in the world.
2015
lab-matters
A powerful HMMER for data mining
Lab Matters HMMER – a fast, sensitive search tool – helps find sequence relationships deep in evolutionary time.
2015
lab-matters
ELIXIR accelerates
Lab Matters ELIXIR receives major Horizon 2020 funding to ‘EXCELERATE' activities over the next four years.
2015
lab-matters
Oceans endeavour charts 40 million genes
Science Tara Oceans results reveal climate change insights, and a treasure trove of novel species and genes.
2015
science
PDBe launches new website
Lab Matters In their quest to make structural biology more accessible, PDBe launches a new website.
2015
lab-matters
Bioinformatics services: Winter 2015
Lab Matters A quick round-up of the latest EMBL-EBI service releases.
2015
lab-matters
500,000 binary interactions… and growing
Lab Matters Building and visualising protein-interaction networks is easier and more accurate thanks to IntAct.
2015
lab-matters
Why is a dolphin not a cat?
Science How repurposing non-coding elements in the genome gave rise to the great ‘mammalian radiation’.
2015
science
Moving 20 Petabytes
Lab Matters A blog extract by Ewan Birney reflects on the challenges of moving a massive data-centre.
2015
lab-matters
Beyond COMPARE
Lab Matters New project aims to speed up detection and response to disease outbreaks using genome technology.
2015
lab-matters
What makes a mosquito deadly?
Science Genome-based insights into evolution of malaria-carrying Anopheles mosquitoes.
2014
science
Record parasitic worm dataset
Science Largest collection of helminth genomic data ever assembled, in new open-access WormBase ParaSite.
2014
science
Big (Protein) Data to Knowledge
Lab Matters 'Big Data to Knowledge' project by UCLA, Scripps and EMBL-EBI to transform protein data to knowledge.
2014
lab-matters
Building an EMPIAR
Science EMPIAR lets researchers take a closer look at the images used to build 3D molecular structures.
2014
science
Same pieces, different picture
Science Unprecedented detail on HIV structure continues virus’ string of surprises.
2014
science
Computational modelling resource
Science New, open repository helps researchers share computational models of disease.
2014
science
European Variation Archive launches
Science European Variation Archive makes it easier to explore detailed information about genetic variation.
2014
science
Job dispatched
Lab Matters How does EMBL-EBI run millions of jobs for its users while moving its two large data centres?
2014
lab-matters
Blog roundup: September
Lab Matters Pathfinding – poetic and practical – was a common theme in blogs from the EMBL network.
2014
lab-matters
Genotype to phenotype mapping course
Events EMBL-EBI hosts successful first EMBO Practical Course in Genotype to Phenotype Mapping.
2014
events
RNAcentral Station
Science RNAcentral is the first unified resource for all types of non-coding RNA data.
2014
science
How do animals become domesticated?
Science Bronwen Aken discusses what research into the rabbit genome reveals about animal domestication.
2014
science
Art inspired by data science
Lab Matters Artist Stephen Wright gifts artwork inspired by DNA storage research to EMBL-EBI.
2014
lab-matters
Bioinformatics services: Summer 2014
Lab Matters A quick round-up of the latest EMBL-EBI service releases
2014
lab-matters
New EMBL-EBI data centre contract
Lab Matters Gyron Ltd awarded contract to supply EMBL-EBI's data centres over the next five years
2014
lab-matters
New, improved human genome
Science Ensembl has incorporated a vast amount of knowledge into a fully annotated reference human genome
2014
science
New genomics API
Lab Matters New genomics API allows researchers to share anonymised genetic data seamlessly across platforms.
2014
lab-matters
Shedding light on chimeral twins
Science Marmoset genome provides insights into chimerism: data available in Ensembl genome explorer
2014
science
The future’s bright
Science Surprising protein from a flu-like virus is 10 000th ESRF structure
2014
science
Resourceful alumni
Alumni Two EMBL alumni, each developing community-led tools to support life science research
2014
alumni
The shape of things to come
Science New ways of handling and distributing data at PDBe to tackle ever larger and more complex proteins
2014
science
On target
Lab Matters A new EMBL-EBI biomedical initiative works to determine the best target proteins for new drugs.
2014
lab-matters
Capturing marine biodiversity
Science Data from first ever worldwide Ocean Sampling Day will be shared via EMBL-EBI resources this autumn.
2014
science
Cross-Channel collaboration
Events Teaming up in Ireland to address big challenges in biology
2014
events
Sheep genome provides rich resource for agricultural research
Science Reference sheep genome, published by International Sheep Genomics Consortium, available in Ensembl
2014
science
How immune cells use steroids
Science Genome Campus researchers discover that some immune cells turn themselves off by producing a steroid.
2014
science
Tsetse fly genome sequenced
Science Tsetse fly genome sequenced; scientists hope to find new ways to control sleeping sickness.
2014
science
Variations on the genetic theme
Science Just like members of an orchestra are active at different times although playing the same piece of music, every cell in our body contains the same genetic sequence but expresses this differently to give rise to cells and tissues with specialised properties. By integrating gene expression data from…
2010
science
ArrayExpress database doubles in size to 100,000 hybridisations
Lab Matters ArrayExpress, the publicly available database of transcriptomics data at the European Molecular Biology Laboratory’s European Bioinformatics Institute (EMBL-EBI), has doubled in size in 2007, reaching the 100,000-hybridisation milestone. The database now holds snapshots of gene expression…
2007
lab-matters
Uncovering the secrets of the deep
Science The UniProt Consortium, which includes the European Molecular Biology Laboratory’s European Bioinformatics Institute (EMBL-EBI), has added a new database repository for metagenomic and environmental data to its family of protein sequence databases. Metagenomics is the large-scale genomic…
2007
science
The first public nucleotide sequence database turns 25
Lab Matters It was the world’s earliest public database of DNA and RNA sequences and remains Europe’s primary nucleotide sequence resource. The database is maintained by EMBL’s European Bioinformatics Institute in Hinxton (UK) in collaboration with its US and Japanese counterparts GenBank and…
2007
lab-matters
Better, faster, easier
Lab Matters Today the European Molecular Biology Laboratory’s European Bioinformatics Institute (EMBL-EBI) launches its new, faster and easier website with an exhaustive search engine at its centre. The web interface has been streamlined on the basis of user feedback from a recent extensive…
2006
lab-matters
CiteXplore
Lab Matters Today the European Molecular Biology Laboratory’s European Bioinformatics Institute (EMBL-EBI) launches CiteXplore, a new freely accessible literature resource service. Biological researchers require two crucial sources of information: scientific literature published in peerreviewed…
2006
lab-matters
Free access to world-class biological databases for European science thanks to FELICS
Lab Matters Today the European Molecular Biology Laboratory’s (EMBL) European Bioinformatics Institute (EBI), the Swiss Institute for Bioinformatics (SIB), the University of Cologne, Germany, and the European Patent Office launch FELICS (Free European Life-science Information and Computational Services).…
2006
lab-matters
ENFIN! Computational systems biology comes to a lab bench near you
Lab Matters The Commission of the European Union has awarded EUR 9 million over five years for a new Network of Excellence that will make computational systems biology accessible to bench scientists throughout Europe and beyond. ENFIN, which stands for ‘Experimental Network for Functional…
2005
lab-matters
EBI and Ghent University launch PRIDE
Lab Matters The European Bioinformatics Institute and Flanders Interuniversity Institute for Biotechnology (VIB) – Ghent University have launched the PRoteomics IDEntifications database (PRIDE). PRIDE allows researchers who work in the field of proteomics – the large-scale study of proteins – to…
2005
lab-matters
IMEx consortium provides new mechanism for improving access to molecular interaction data
Lab Matters The executive teams of five major molecular interaction databases announced today the signing of an agreement to share curation efforts and exchange completed records through a mechanism known as the International Molecular Exchange (IMEx) consortium. IMEx will provide a network of stable,…
2005
lab-matters
Public collections of DNA and RNA sequence reach 100 gigabases
Lab Matters The world’s three leading public repositories for DNA and RNA sequence information have reached 100 gigabases (100,000,000,000 bases; the ‘letters’ of the genetic code) of sequence. Thanks to their data exchange policy, which has paved the way for the global exchange of many types…
2005
lab-matters
A new way to share models of biological systems
Science Today sees the launch of BioModels, the world’s first database of annotated biological models. BioModels is the result of a collaboration led by the European Bioinformatics Institute (UK) and the SBML Team, an international group that develops opensource standards to describe biological…
2005
science
European bioinformatics grid receives 8 million Euro
Lab Matters The Commission of the European Union has awarded 8.3 million Euro to a pan-European task force who will improve access to biological information for scientists throughout and beyond Europe. The EMBRACE Network of Excellence, which encompasses computational biologists from 17 institutes in 11…
2005
lab-matters
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