ArrayExpress interface now retired
Updates from data resources Data continues to be available in BioStudies.
2022
updates-from-data-resources
Zooming in to get the full picture
Science EMBL and UW researchers plus additional collaborators have constructed a complete map of fruit fly embryonic development using machine learning. This research is foundational to better understanding overall embryo development in other species, including humans.
2022
science
Understanding genomes, piece by piece
Science Genomes are made up of thousands of individual pieces – genes – which are expressed at different levels. Researchers at EMBL have shed light on how the placement of a gene affects its expression, as well as that of its neighbours.
2022
science
Converging lenses on embryo development
Science Researchers from the Furlong group at EMBL have come up with a way to observe the development of fruit-fly embryos simultaneously at the genetic and cellular levels, generating a high-resolution and integrated view of how different cell lineages form.
2022
science
New Expression Atlas release in collaboration with PRIDE
Updates from data resources New Expression Atlas release features differential-proteomics and baseline-proteomics experiments in collaboration with the PRIDE team at EMBL-EBI. This also includes new baseline DIA proteomics experiments as well as new differential proteomics datasets. To improve reproducibility,…
2022
updates-from-data-resources
Cell sorting enters a new dimension
Science EMBL researchers, in collaboration with BD Biosciences, have demonstrated a new technology that allows rapid image-based sorting of cells. The new technology represents a major upgrade to flow cytometry and has applications in diverse life science fields.
2022
science
Capturing ‘snapshots’ of a crucial step in RNA splicing
Science The Galej group at EMBL Grenoble has recently obtained high resolution snapshots of a crucial step in RNA splicing involving the U2 snRNP complex, a crucial component of the human spliceosome.
2022
science
Can data help feed a hungry world?
Science How genomics, open data, and multidisciplinary science can improve food security.
2021
science
A cellular atlas of an entire worm
Science EMBL scientists and colleagues have developed an interactive atlas of the entire marine worm Platynereis dumerilii in its larval stage. The PlatyBrowser resource combines high-resolution gene expression data with volume electron microscopy images.
2021
science
Induced pluripotent stem cells reveal causes of disease
Science Scientists in the Stegle group and colleagues have studied induced pluripotent stem cells from around 1,000 donors to identify correlations between individual genetic variants and altered gene expression. They linked more than 4,000 of the genetic variants responsible for altered expression…
2021
science
At the core of the Integrator complex
Science A new paper from the Galej group at EMBL Grenoble describes the structure of key parts of the Integrator complex, involved in gene expression.
2021
science
Predicting how gene expression varies
Science Discoveries at EMBL will help researchers to interpret one of the most common types of experiments in genomics and medical studies.
2020
science
Muscular worm larva
Picture of the week The image shows a larva of Platynereis dumerilii, a marine worm. The image here was produced by Constantin Pape, a visiting predoctoral fellow in the Kreshuk group at EMBL Heidelberg.
2020
picture-of-the-week
Enabling functional genomics studies in individual cells
Science Scientists at EMBL Heidelberg have developed a new method, called Targeted Perturb-seq (TAP-seq), which increases the scale and precision of functional genomics CRISPR–Cas9 screens by orders of magnitude. Their method overcomes limitations in previous applications of single-cell RNA sequencing,…
2020
science
How chromosome structure influences development
Science EMBL researchers in the Heard group at EMBL Heidelberg explore the interaction between DNA organisation and gene expression in the early embryo
2020
science
Tissue dynamics provide clues to human disease
Science EMBL scientists examine the molecular causes of a rare hereditary disease of the spine and ribs
2020
science
New insights into gene regulation
Science EMBL researchers investigate the role of a histone protein in regulating gene expression
2020
science
Transcriptional hubs confer phenotypic robustness
Science Enhancers in Drosophila embryos gather together to preserve phenotypes under stressful conditions
2019
science
Rearranging chromosomes
Science Does rearranging chromosomes affect their function? EMBL scientists reveal uncoupling of 3D chromatin organisation and gene expression.
2019
science
The scientific origins of Edith Heard
Science EMBL’s next Director General reflects on the questions that drive her research
2018
science
Welcome: Arnaud Krebs
Science EMBL’s new group leader studies how gene expression is controlled
2018
science
Multipurpose enhancers and promoters in embryonic development
Science EMBL scientists show that some promoters can act as enhancers and vice versa
2018
science
Solving the nucleosome: twenty years on
Events Tim Richmond looks back on the work that revealed the high-resolution structure of the nucleosome
2017
events
Mapping gene expression, cell by cell
Science EMBL researchers complete a molecular atlas showing gene expression in all cells in an entire animal
2017
science
Senses: Silencing noise
Science Two EMBL researchers are exploring new ways to filter out noise and get to the data they need
2017
science
Futures: Genome regulation
Science ERC grantee Eileen Furlong shares her vision for the next ten years
2017
science
Genetics of ‘room-mate’ influences health
Science Healing and anxiety are influenced by the genetics of one’s social partners
2017
science
Welcome: Wojciech Galej
Science New group leader Wojciech Galej investigates RNA-protein complexes involved in gene expression
2017
science
Chromatin cartographer
Alumni EMBL alumnus Jop Kind reflects on the questions that led him to this year’s John Kendrew Award
2016
alumni
Unpacking embryonic pluripotency
Science Embryology, genomics and bioinformatics combine to identify factors regulating mammalian pluripotency.
2015
science
A snapshot of stem cell expression
Science Study of mouse embryonic stem cells reveals new genes involved in the stem-cell regulatory network.
2015
science
Towards an expression atlas for an entire brain
Science New single-cell genomics techniques bring ‘omics to evolution and development research.
2015
science
Tracking genes’ remote controls
Science As an embryo develops, different genes are turned on in different cells, to form muscles, neurons and other bodily parts. Inside each cell’s nucleus, genetic sequences known as enhancers act like remote controls, switching genes on and off. Scientists at the European Molecular Biology Laboratory…
2012
science
Deciphering the regulatory code
Science Embryonic development is like a well-organised building project, with the embryo’s DNA serving as the blueprint from which all construction details are derived. Cells carry out different functions according to a developmental plan, by expressing, i.e. turning on, different combinations of genes.…
2009
science
Sugarcoating fruit fly development
Science Proteins are the executive agents that carry out all processes in a cell. Their activity is controlled and modified with the help of small chemical tags that can be dynamically added to and removed from the protein. 25 years after its first discovery, researchers at the European Molecular Biology…
2009
science
New revelations in epigenetic control shed light on breast cancer
Science Epigenetic regulation – modifications to the structure of chromatin that influence which genes are expressed in a cell – is a key player in embryonic development and cancer formation. Researchers at the European Molecular Biology Laboratory (EMBL) in Heidelberg now gained new insight…
2008
science
No matching posts found
