Edit

gene expression

4 March 2021 An illustration of single-cell RNA sequencing (scRNA-seq)

Induced pluripotent stem cells reveal causes of disease

5 February 2021 Artistic representation of the structure of the three proteins forming Integrator’s catalytic core.

At the core of the Integrator complex

19 August 2020 An embryo of the fruit fly Drosophila.

Predicting how gene expression varies

14 July 2020 The image shows a larva of Platynereis dumerilii, a marine worm. The body of the worm is shown in grey. Muscle strands are coloured in red. The muscles of one individual strand are highlighted in different, brighter colours.

The image shows a larva of Platynereis dumerilii, a marine worm. The body of the worm is shown in grey. Muscle strands are coloured in red. The muscles of one individual strand are highlighted in different, brighter colours.

Muscular worm larva

1 June 2020 An illustration of single-cell RNA sequencing (scRNA-seq)

Enabling functional genomics studies in individual cells

9 April 2020 3D reconstruction of parental chromosomes in the mouse embryo

How chromosome structure influences development

3 April 2020 oscillations of gene activity

Tissue dynamics provide clues to human disease

5 March 2020

New insights into gene regulation

24 July 2019 Stripes of colour display gene expression patterns

Transcriptional hubs confer phenotypic robustness

15 July 2019

The pyramids represent chromatin domains in the wild-type situation. The reflection in the water below represents the rearrangements in the mutant fruit fly chromosomes. At first glance the (regulatory) landscapes look very similar, but there are lots of changes to the topology, and yet these have little impact on the nature of the landscape (gene expression). IMAGE: Beata Edyta Mierzwa in collaboration with EMBL.

Rearranging chromosomes

28 May 2018 In this image of developing cells, fluorescent molecules reveal DNA (blue), part of the X chromosomes (red), and the Xist RNA (white). The green colour shows a region of the cells’ nuclei called the nuclear lamina. IMAGE: Mikael Attia and Edith Heard/Institut Curie