23 November 2023
Alba Diz-Muñoz and Arnaud Krebs from EMBL Heidelberg have received grants to work on projects that aim, respectively, to understand the cellular mechanics that control cell division and investigate the regulatory networks that govern transcription factor function.
24 July 2023
EMBL researchers have made new strides into understanding and reversing genetic defects that underlie familial heart disease.
20 July 2023
Updates from data resources
The latest Expression Atlas release is now live and contains a wider range of RNA-seq and proteomics datasets.
14 July 2023
EMBL researchers use a new cell sorting technology to gain new insights into cellular function in health and disease, as well as for other innovative applications.
2 June 2023
Science, Technology and innovation
A new tool for the interpretation of missense variation in humans – ProtVar – will help enable drug discovery.
7 February 2023
EMBL Grenoble scientists provide new insights into the function of an essential RNA editing enzyme.
19 October 2022
Updates from data resources
Data continues to be available in BioStudies.
4 August 2022
EMBL and UW researchers plus additional collaborators have constructed a complete map of fruit fly embryonic development using machine learning. This research is foundational to better understanding overall embryo development in other species, including humans.
4 March 2022
Genomes are made up of thousands of individual pieces – genes – which are expressed at different levels. Researchers at EMBL have shed light on how the placement of a gene affects its expression, as well as that of its neighbours.
25 February 2022
Researchers from the Furlong group at EMBL have come up with a way to observe the development of fruit-fly embryos simultaneously at the genetic and cellular levels, generating a high-resolution and integrated view of how different cell lineages form.
24 February 2022
Updates from data resources
New Expression Atlas release features differential-proteomics and baseline-proteomics experiments in collaboration with the PRIDE team at EMBL-EBI. This also includes new baseline DIA proteomics experiments as well as new differential proteomics datasets. To improve reproducibility,…
21 January 2022
EMBL researchers, in collaboration with BD Biosciences, have demonstrated a new technology that allows rapid image-based sorting of cells. The new technology represents a major upgrade to flow cytometry and has applications in diverse life science fields.
18 January 2022
The Galej group at EMBL Grenoble has recently obtained high resolution snapshots of a crucial step in RNA splicing involving the U2 snRNP complex, a crucial component of the human spliceosome.
16 November 2021
How genomics, open data, and multidisciplinary science can improve food security.
5 October 2021
EMBL scientists and colleagues have developed an interactive atlas of the entire marine worm Platynereis dumerilii in its larval stage. The PlatyBrowser resource combines high-resolution gene expression data with volume electron microscopy images.
4 March 2021
Scientists in the Stegle group and colleagues have studied induced pluripotent stem cells from around 1,000 donors to identify correlations between individual genetic variants and altered gene expression. They linked more than 4,000 of the genetic variants responsible for altered expression…
5 February 2021
A new paper from the Galej group at EMBL Grenoble describes the structure of key parts of the Integrator complex, involved in gene expression.
19 August 2020
Discoveries at EMBL will help researchers to interpret one of the most common types of experiments in genomics and medical studies.
14 July 2020
Picture of the week
The image shows a larva of Platynereis dumerilii, a marine worm. The image here was produced by Constantin Pape, a visiting predoctoral fellow in the Kreshuk group at EMBL Heidelberg.
1 June 2020
Scientists at EMBL Heidelberg have developed a new method, called Targeted Perturb-seq (TAP-seq), which increases the scale and precision of functional genomics CRISPR–Cas9 screens by orders of magnitude. Their method overcomes limitations in previous applications of single-cell RNA sequencing,…
9 April 2020
EMBL researchers in the Heard group at EMBL Heidelberg explore the interaction between DNA organisation and gene expression in the early embryo
3 April 2020
EMBL scientists examine the molecular causes of a rare hereditary disease of the spine and ribs
5 March 2020
EMBL researchers investigate the role of a histone protein in regulating gene expression
24 July 2019
Enhancers in Drosophila embryos gather together to preserve phenotypes under stressful conditions
15 July 2019
Does rearranging chromosomes affect their function? EMBL scientists reveal uncoupling of 3D chromatin organisation and gene expression.
28 May 2018
EMBL’s next Director General reflects on the questions that drive her research
9 February 2018
EMBL’s new group leader studies how gene expression is controlled
30 January 2018
EMBL scientists show that some promoters can act as enhancers and vice versa
29 June 2017
Tim Richmond looks back on the work that revealed the high-resolution structure of the nucleosome
9 June 2017
EMBL researchers complete a molecular atlas showing gene expression in all cells in an entire animal
6 June 2017
Two EMBL researchers are exploring new ways to filter out noise and get to the data they need
13 March 2017
ERC grantee Eileen Furlong shares her vision for the next ten years
26 January 2017
Healing and anxiety are influenced by the genetics of one’s social partners
25 January 2017
New group leader Wojciech Galej investigates RNA-protein complexes involved in gene expression
24 November 2016
EMBL alumnus Jop Kind reflects on the questions that led him to this year’s John Kendrew Award
9 November 2015
Embryology, genomics and bioinformatics combine to identify factors regulating mammalian pluripotency.
14 October 2015
Study of mouse embryonic stem cells reveals new genes involved in the stem-cell regulatory network.
14 April 2015
New single-cell genomics techniques bring ‘omics to evolution and development research.
8 January 2012
As an embryo develops, different genes are turned on in different cells, to form muscles, neurons and other bodily parts. Inside each cell’s nucleus, genetic sequences known as enhancers act like remote controls, switching genes on and off. Scientists at the European Molecular Biology Laboratory…
4 November 2009
Embryonic development is like a well-organised building project, with the embryo’s DNA serving as the blueprint from which all construction details are derived. Cells carry out different functions according to a developmental plan, by expressing, i.e. turning on, different combinations of genes.…
28 May 2009
Proteins are the executive agents that carry out all processes in a cell. Their activity is controlled and modified with the help of small chemical tags that can be dynamically added to and removed from the protein. 25 years after its first discovery, researchers at the European Molecular Biology…
6 March 2008
Epigenetic regulation – modifications to the structure of chromatin that influence which genes are expressed in a cell – is a key player in embryonic development and cancer formation. Researchers at the European Molecular Biology Laboratory (EMBL) in Heidelberg now gained new insight…
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