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Coronavirus

The SARS-CoV-2 B.1.1.7 lineage

A note on the coronavirus variant B.1.1.7, which has first been described in the U.K. and has spread to 57 countries. The note summarises…

By Guest author(s)

Science

3D rendering of a human cell, attacked by a virus.

Cell under attack

It’s almost a year since the coronavirus outbreak was declared a pandemic, affecting all our lives. While the virus continues its grip on the…

By Mathias Jäger

Picture of the week

Tube-like structures of a cell at sub-cellular level in red and grey.

Replication cycle of SARS-CoV-2 in 3D

Researchers have studied SARS-CoV-2 replication in cells and obtained detailed insights into the alterations induced in infected cells. This…

By Mathias Jäger

Science

SARS-CoV-2 is represented as a sphere with spike proteins poking out of its surface, which give it a corona-like appearance. The spike proteins resemble triangular ‘bushes’ with three tips at the top. In the background, a cell surface is visible with ACE2 proteins poking out of it in many places. The virus is about to attach to the cell surface. The sybodies, represented as tiny V-shaped structures, bind to the viral spike proteins at their tips.

Scientists identify synthetic mini-antibody to combat COVID-19

By screening hundreds of sybodies (synthetic mini-antibodies), scientists have identified one that might stop SARS-CoV-2 from infecting human cells.…

By Dorota Badowska

Science

Open access COVID-19 data sharing

Open data sharing accelerates COVID-19 research

Open access data benefits millions of scientists around the world and is essential for a rapid response to the COVID-19…

By Vicky Hatch

Science

Four blue circular objects are surrounded with green structures, and the central blue circle with pink structures. The blue circles are human cell nuclei, and pink and green structures are proteins.

Repurposing drugs for a pan-coronavirus treatment

Scientists from the Beltrao Group at EMBL-EBI and collaborators identified drug targets common to SARS-CoV-2, SARS-CoV-1, and MERS-CoV, three…

By Vicky Hatch

Science

Illustration showing globe, statistics and viruses

Funding to predict the risk of infectious disease outbreaks

European collaboration receives funding to explore risks and impact of future infectious disease…

By Oana Stroe

Lab Matters

Artwort illustrating various aspects of infection research. The centre of the image shows a cartoon representation of a coronavirus. The spheric shape has been overlaid with a map of the world to illustrate the global spread of viruses. The edges of the artwork feature images of potential virus hosts (bats, poultry, dromedary), a group of humans, a microscope, pills, a syringe and vaccine vial, protein structures, and an illustration of a human lung. The background is set in yellow and red colour.

What COVID-19 is teaching us

The virtual EMBL Conference ‘SARS-CoV-2: Towards a New Era in Infection Research’ explored the importance of fundamental research, collaboration,…

By Marius Bruer

Events

Gene Editing and Embryology Facility at EMBL Rome

Editing the mouse genome to study SARS-CoV-2 infection

To study how SARS-CoV-2 infects cells, the Gene Editing and Embryology Facility (GEEF) at EMBL Rome will generate mice that express a human version…

By Rossana De Lorenzi

Science

SARS-CoV-2 viruses visible on proteins

Existing drugs can prevent SARS-CoV-2 from hijacking cells

Researchers evaluate how the new coronavirus rewires human proteins for its own replication, and identify several antiviral drugs ready for clinical…

By Mehdi Khadraoui

Science

Scientists in the Hackett group at EMBL Rome doing lab work

Silencing the SARS-CoV-2 receptor with epigenetic modifications

EMBL scientists develop a new molecular tool to prevent SARS-CoV-2 infection in mice. This tool is able to cause targeted epigenetic modifications of…

By Rossana De Lorenzi

Science

77% of the life science institutes are shut down. 57% of the asked scientists lost up to 6 months of work. 66% use the extra time for career development. 18% now take part in COVID-19 research. 30% have so far attended a virtual conference.

EMBL survey studies effects of COVID-19 pandemic on life scientists

Jan Korbel and Oliver Stegle have performed a survey of fellow life scientists to learn how the current crisis, with partial or complete…

By Mathias Jäger

Lab Matters

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