MAGIC: AI-assisted laser tag illuminates cancer origins
EMBL researchers have developed a new AI tool, which, through a game of molecular laser tag, is helping us better understand the origins of cancer.
SCIENCE & TECHNOLOGY2025
science-technology
AI analysis for bioimages – what’s missing?
Lack of incentives and low adoption of metadata standards are limiting AI’s potential for bioimage analysis – a new paper proposes solutions.
SCIENCE & TECHNOLOGY2025
science-technologytechnology-and-innovation
New PDBe entry pages: Interactive, personalised, and mobile-ready
Explore molecular structures with new interactive 3D viewers and AI annotations
2025
updates-from-data-resources
AI model forecasts disease risk decades in advance
New AI model can estimate the long-term risk of over 1,000 diseases and forecast human health changes over a decade in advance.
SCIENCE & TECHNOLOGY2025
research-highlightsscience-technology
Welcome: Jess Ewald
Jess Ewald, Research Group Leader at EMBL-EBI, uses cell profiling and AI to find and characterise chemical hazards to humans and ecosysystems.
PEOPLE & PERSPECTIVES2025
people-perspectivesperspectives
New AlphaFold Database entry pages
The AlphaFold Protein Structure Database (AFDB) has redesigned its entry pages to make exploring predicted protein structures faster, clearer, and more intuitive. This update delivers a streamlined experience across devices, whether you’re browsing from the lab, your desktop, or on the move.…
2025
updates-from-data-resources
AI in the life sciences: philanthropy fuels EMBL’s strategy
EMBL’s new AI strategy, backed by the German Hector Foundation, integrates AI across all areas of the life sciences to drive breakthroughs and innovation.
CONNECTIONS2025
connections
CORNETO: machine learning to decode complex omics data
New tool combines biological knowledge with machine learning to help researchers extract meaningful insights from complex omics data.
SCIENCE & TECHNOLOGY2025
research-highlightssciencescience-technology
New Wellcome funding model supports the development of EMBL-EBI open data resources
EMBL’s European Bioinformatics Institute (EMBL-EBI) manages the world’s most comprehensive suite of open data resources for the life sciences. Millions of scientists worldwide rely on these data resources. The breadth of usage has been expanding year on year, as researchers generate increasing…
2025
announcements
New platform calculating polygenic scores
A new EMBL-EBI platform reduces bioinformatics barriers to applying polygenic scores in disease risk research.
2025
updates-from-data-resources
The future of European life sciences
EMBL’s position paper outlines its key recommendations for European Commission’s upcoming ‘Strategy for European Life Sciences’.
EMBL ANNOUNCEMENTS2025
embl-announcements
InterPro 105.0: AI for protein classification
InterPro 105.0 is now live. This AI-driven update makes it easier than ever to explore the protein universe.
2025
updates-from-data-resources
EMBL Partnership Conference explores AI in One Health
Fifth EMBL Partnership Conference brings together participants from EMBL and partner institutions to explore how AI can drive innovation in One Health. Conference participants discussed opportunities and challenges in advancing AI in life sciences and the role collaboration.
CONNECTIONS2025
connections
How AI fuels research, discovery, and innovation
This year’s EMBL Corporate Partnership Programme annual meeting connected EMBL scientists with industry representatives to talk about AI and life sciences research.
CONNECTIONS2025
connections
BioChatter: making large language models accessible for biomedical research
Introducing an open-source large language model (LLM) framework designed for custom biomedical research.
SCIENCE & TECHNOLOGY2025
research-highlightsscience-technology
New strategic partnership for AI in the sciences
Memorandum of Understanding between EMBL and ELLIS will drive AI in European life science research, training, and technology. The strategic partnership will promote interdisciplinary training and develop innovative projects that address pressing challenges in human and planetary health.
CONNECTIONS2025
connections
Microbial load can influence disease associations
Scientists have developed a new machine-learning model to predict microbial load — the density of microbes in our guts — and used it to demonstrate how microbial load plays an important role in disease-microbiome associations.
SCIENCE & TECHNOLOGY2024
science-technology
Computational protein design and protein structure prediction win Nobel Prize in Chemistry
Creators of AI system AlphaFold receive 2024 Nobel Prize for Chemistry.
SCIENCE & TECHNOLOGY2024
sciencescience-technology
Machine learning discoveries honoured with 2024 Nobel Prize for Physics
The prize was awarded to John J. Hopfield, Princeton University, USA, and Geoffrey Hinton, University of Toronto, Canada, for their seminal contributions to the foundational methods that enabled the development of machine learning.
SCIENCE & TECHNOLOGY2024
science-technology
New MGnify Proteins web resources launched
EMBL-EBI’s microbiome data resource MGnify produces a valuable trove of protein sequence data through its ongoing analysis of microbiome derived data. Two new MGnify Proteins web resources make this dataset easily accessible and searchable, both for large queries across the entire database…
2024
updates-from-data-resources
AlphaFold database empowers researchers with enhanced structural search via Foldseek integration
Traditional sequence search methods are fast and efficient but rely solely on comparing amino acid sequences. This approach can miss crucial insights because proteins with similar functions can have vastly different sequences. Although their sequences have diverged, these proteins often retain 3D…
2024
updates-from-data-resources
Follow the cellular road
An AI-enhanced advanced microscopy approach offers promise in better understanding glioblastomas, one of the deadliest brain cancers.
SCIENCE & TECHNOLOGY2024
science-technology
The EMBL evolution: Ewan Birney on open data and the ethos of excellence
Ewan Birney reflects on his time at EMBL and the development of the organisation through a commitment to open data and nurturing scientific talent.
PEOPLE & PERSPECTIVES2024
people-perspectivesperspectives
AI approaches in structural biology and drug discovery
EMBL Grenoble and the ESRF hosted a workshop bringing together representatives from research and industry to discuss the ever-growing role of artificial intelligence in the field of structural biology.
CONNECTIONS2024
connections
When AI meets biology
A recent EMBO | EMBL conference provided a forum for researchers to share how AI is making a difference in biology and bioinformatics.
SCIENCE & TECHNOLOGY2024
science-technology
AI annotations increase patent data in SureCheMBL
AI annotations added to the SureChEMBL database increase the depth of data made available to users.
2024
sciencetechnology-and-innovation
The AI revolution hinges on accessible training
Team Leader Sameer Velankar on why accessible training is key for AlphaFold and AI tools more generally.
PEOPLE & PERSPECTIVES2024
people-perspectivesperspectivesscience
ProteomicsML: empowering proteomics research with machine learning
Streamlining proteomics data access for machine learning applications.
2024
sciencetechnology-and-innovation
RNA to rule them all
The Kosinski Group at EMBL Hamburg collaborated with other groups in Hamburg to reveal critical steps in Lassa virus ribonucleoparticle assembly and recruitment, and the crucial role played by RNA in in the Lassa virus life cycle.
SCIENCE & TECHNOLOGY2023
sciencescience-technology
Using artificial intelligence to discover therapeutic antibodies
Former EMBL staff scientist founds a start-up – DenovAI – for broader, faster and cheaper antibody discovery using advanced machine learning and computational biophysics.
SCIENCE & TECHNOLOGY2023
sciencescience-technology
How AI shapes the life sciences: an interview with Oliver Stegle
EMBL scientist Oliver Stegle explains how AI-based tools have the potential to transform our ability to better understand the complexity of life and how these tools will shape the future of life science exploration.
LAB MATTERSPEOPLE & PERSPECTIVES2023
lab-matterspeople-perspectives
Deciphering the data deluge: how large language models are transforming scientific data curation
Large language models are changing the way we carry out scientific data curation, annotation, and research, setting the stage for a more efficient understanding of scientific literature
2023
technology-and-innovation
Reducing the carbon footprint of scientific computing
As science increasingly relies on big data and AI tools, the carbon footprint of computational work is on the rise
2023
perspectives
A leap in user experience: AlphaFold Database introduces sequence-based search and structure cluster members
In response to user community demands, the AlphaFold Protein Structure database has introduced sequence-based search and cluster members.
2023
updates-from-data-resources
AI in biology and health: opportunities and challenges
EMBL gathered together government, industry, and academic researchers to explore how to leverage the power of AI and machine learning to advance research.
CONNECTIONSLAB MATTERS2023
connectionslab-matters
AI at EMBL: enabling responsible innovations in the life sciences
EMBL stands as a leader, exemplifying how to harmoniously integrate AI in research and through its delivery of data services.
LAB MATTERSPEOPLE & PERSPECTIVES2023
lab-matterspeople-perspectives
EMBL receives German AI prize
EMBL receives the German AI prize awarded for outstanding services to the research and development as well as application and commercialisation of artificial intelligence (AI) in life science research.
EMBL ANNOUNCEMENTS2023
embl-announcementsscience
New predictions of genetic variant pathogenicity using AlphaFold protein structures
Ensembl Variant Effect Predictor integrates Google DeepMind’s new AlphaMissense Database for better predictions of genetic variant pathogenicity.
SCIENCE & TECHNOLOGY2023
science-technologytechnology-and-innovation
Revealing the secrets of protein evolution using the AlphaFold database
Researchers use the AlphaFold database and Foldseek Cluster algorithm to analyse millions of predicted protein structures and offer new insights into protein evolution.
SCIENCE & TECHNOLOGY2023
research-highlightssciencescience-technology
EMBL alumni: Laura Clarke on the importance of data management
Experience in data management and coordination has enabled EMBL alumna Laura Clarke to pursue a career in AI development.
PEOPLE & PERSPECTIVES2023
people-perspectivesperspectivesscience
Major user experience update in AlphaFold Database
The AlphaFold Database boasts improved user experience, including better search filters and an improved 3D viewer.
2023
updates-from-data-resources
Terra Incognita: exploring new horizons in scientific ethics
EMBL’s upcoming Science & Society conference takes a deep dive into the ethical considerations surrounding the use of technology and organoids in life science research.
EMBLetc2023
New EU-funded Project: Fragment-Screen
EMBL is one of the partners of this project that aims to accelerate drug discovery and development, bringing in expertise from EMBL Grenoble and EMBL-EBI.
LAB MATTERSSCIENCE & TECHNOLOGY2023
lab-mattersscience-technology
Case study: AlphaFold uses open data and AI to discover the 3D protein universe
Open data played a pivotal role in the development of the AlphaFold AI. The same open principles now apply to AlphaFold predictions.
2023
perspectivesscience
AI helps scientists decipher cellular structures
New artificial intelligence tool adds speed and detailed cellular information to analysis of cryo-electron tomography to aid researchers’ understanding of inner cell workings.
2023
science
Machine learning to identify and prioritise drug targets
Open Targets is using artificial intelligence and machine learning to identify and prioritise drug targets.
SCIENCE & TECHNOLOGY2023
sciencescience-technologytechnology-and-innovation
AlphaFold applications – a community assessment
Researchers use social media to share findings on how useful AlphaFold predictions are for different applications.
2022
research-highlightsscience
AI4LIFE: AI models for bioimaging
Researchers across EMBL are helping to make artificial intelligence (AI) models for bioimaging analysis interoperable and openly available to the scientific community.
2022
announcementsscience
Natural language processing for rapid protein annotation
Over 40 million protein annotations have been added to the UniProt database using a Google Research natural language processing model.
2022
technology-and-innovation
EMBL Barcelona and CRG kickstart new era of digital biology in Barcelona
The institutes have launched a joint new initiative which aims to make biology as engineerable as an aeroplane or a bridge.
CONNECTIONSLAB MATTERS2022
connectionslab-matters
AlphaFold: where will the next AI breakthrough come from?
Ewan Birney, Deputy Director General of EMBL and Director of EMBL-EBI, reveals the key factors that enabled AlphaFold to change the world of biology.
PEOPLE & PERSPECTIVES2022
people-perspectivesperspectivesscience
Puzzling out the structure of a molecular giant
Scientists have solved several mysteries around the structure and function of a true molecular giant: the human nuclear pore complex. They created the most complete model of the complex thanks to combining the program AlphaFold2 with cryo-electron tomography, integrative modelling, molecular…
SCIENCE & TECHNOLOGY2022
sciencescience-technology
A machine learning approach for allocating gene function
Researchers in the Ensembl team are making the most of machine learning methods to speed up genome annotation pipelines
SCIENCE & TECHNOLOGY2022
sciencescience-technologytechnology-and-innovation
Europe PMC: Harnessing the power of text mining to accelerate life sciences research
How text mining collaborations benefit our research, data resources, and the wider scientific community.
SCIENCE & TECHNOLOGY2022
sciencescience-technologytechnology-and-innovation
2.4 billion sequences now available in the latest MGnify protein database release
2.4 billion protein sequences are now available in the latest MGnify release including new annotations provided by Google AI
2022
updates-from-data-resources
Deep learning models help predict protein function
Deep learning models can improve protein annotations and has helped expand the Pfam database.
SCIENCE & TECHNOLOGY2022
perspectivessciencescience-technology
Learning from Deep Learning: the inspirational story behind AlphaFold
DeepMind visits EMBL Heidelberg to discuss current and future implications of Artificial Intelligence for life science research.
SCIENCE & TECHNOLOGY2022
sciencescience-technology
A new era for European molecular biology
EMBL announces details about its next programme, ‘Molecules to Ecosystems’. It will guide studying life across scales and in context with changing environments.
EMBL ANNOUNCEMENTSLAB MATTERS2022
announcementsembl-announcementslab-matters
Artificial intelligence — a scientific game changer in 2021
The systematic application of AI in life sciences as in the AlphaFold algorithm for predicting protein structures has been named '2021 Breakthrough of the Year' by Science magazine.
SCIENCE & TECHNOLOGY2021
sciencescience-technology
DeepMind and EMBL release the most complete database of predicted 3D structures of human proteins
Partners use AlphaFold, the AI system recognised last year as a solution to the protein structure prediction problem, to release more than 350,000 protein structure predictions including the entire human proteome to the scientific community.
SCIENCE & TECHNOLOGY2021
sciencescience-technology
Accessible 3D protein models to accelerate scientific discovery
DeepMind and EMBL-EBI to make millions of protein structure predictions freely available to the scientific community.
SCIENCE & TECHNOLOGY2021
sciencescience-technology
Illuminating protein complexes in cells
EMBL group leaders Julia Mahamid, Anna Kreshuk & Jonas Ries awarded Chan Zuckerberg Initiative grant to advance what we see inside cells.
LAB MATTERSPEOPLE & PERSPECTIVES2021
lab-matterspeople-perspectives
Artificial intelligence makes great microscopes better than ever
EMBL scientists have combined artificial intelligence (AI) algorithms with two cutting-edge microscopy techniques.
SCIENCE & TECHNOLOGY2021
sciencescience-technology
Solving the protein structure puzzle
How artificial intelligence can help us solve the mysteries of the protein universe
SCIENCE & TECHNOLOGY2020
sciencescience-technology
Bringing AI out of the black box
Why should researchers make artificial intelligence more transparent and how can they do it?
LAB MATTERSSCIENCE & TECHNOLOGY2020
lab-mattersscience-technology
Intelligent software tackles plant cell jigsaw
Starting with computer code and moving on to a more user-friendly graphical interface called PlantSeg, the Kreshuk Group at EMBL and collaborators built a simple open-access method to provide the most accurate and versatile analysis of plant tissue development to date.
SCIENCE & TECHNOLOGY2020
sciencescience-technology
New clues to a 500-year old mystery about the human heart
An international team of scientists involving Ewan Birney's group has investigated the function of a complex mesh of muscle fibres that line the inner surface of the heart.
SCIENCE & TECHNOLOGY2020
sciencescience-technology
Bridging artificial intelligence and the life sciences – launch of ELLIS Heidelberg
Researchers from all life science disciplines – from fundamental biological research to medical applications – generate immense datasets. Analysing these datasets and gaining new knowledge from them is a growing challenge for scientists. The fields of artificial intelligence (AI) and machine…
LAB MATTERSSCIENCE & TECHNOLOGY2020
lab-mattersscience-technology
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