Scientists at EMBL Barcelona focus on tissue biology and disease modelling
Molecular biology underpins our understanding of life, but the human body is more than just a collection of incredible molecules and fascinating cell types. The correct functioning of our bodies also depends on a higher level of organisation: how millions of different cells interact with each other – chemically, physically and dynamically – to form healthy tissues and organs.
Keep reading about EMBL Barcelona's work
At EMBL Barcelona, we go beyond the molecular and cellular scale to ask questions such as:
How do thousands of cells dynamically self-organise to create tissues and organs?
Why does this sometimes go wrong, causing birth defects?
How could we repair damaged tissues?
Why does an efficient blood vessel depend on interactions between multiple different cell types?
How do infectious diseases attack tissues?
Can we engineer healthy or novel tissues in the laboratory?
How do the physical properties of tissues influence their dynamics?
Can we go beyond animal models, and use bio-engineered tissues to develop treatments for diseases such as cancer or malaria?
To tackle these grand challenges, we combine an interdisciplinary mix of approaches. We integrate molecular and cellular data with tissue engineering, multicellular omics, 3D mesoscopic imaging, computer modelling and gene circuits. Currently our research topics cover embryonic organoids, organ development, in vitro vascular models and disease modelling.
In this highly collaborative and international environment, EMBL researchers benefit from partnerships and collaborations with the Centre for Genomic Regulation (CRG), the Institute for Bioengineering of Catalonia (IBEC), the Spanish National Research Council (CSIC), and other pioneering research institutes, both on campus and in the region. Perched on the Barcelona seafront, and within walking distance of the city’s iconic architecture, the site is bathed in the energy of this bustling, creative metropolis.
A pioneering tool that enables 3D imaging of biological tissues, combining the ability to capture fine details with the capacity to study relatively large samples for extended periods of time.
A hub for research which aims to bring together experts from different disciplines to work on modelling and predictive biology. This is a joint project between EMBL Barcelona and CRG.
EMBL Barcelona has built strong ties within the PRBB community and the rest of the Spanish scientific landscape.
Fostering EMBL’s missions to perform fundamental research as well as to integrate European life science research, EMBL Barcelona has established key collaborations in the following areas.
With support from more than 30 countries, laboratories at six sites across Europe and thousands of scientists and engineers working together, the European Molecular Biology Laboratory (EMBL) is a powerhouse of biological expertise. EMBL is an intergovernmental organisation, headquartered in Heidelberg, and was founded in 1974 with the mission of promoting molecular biology research in Europe, training young scientists, and developing new technologies.
Publishing hundreds of research articles and hosting dozens of conferences every year, EMBL is driving visionary fundamental research and training Europe’s future scientific talent.