1 July 2022, 11:00

Socially induced brain plasticity and behavioral reprogramming in ants

Social insects are an ideal system to study the role of gene regulation in brain development and function because individuals from different castes (workers and queens) display dramatic different behaviors despite sharing the same genome. Social insects are an ideal system to study the role of gene regulation in brain development and function because individuals from different castes (workers and queens) display dramatic different behaviors despite sharing the same genome. We have been developing the ant Harpegnathos saltator as a model organism because of its unique phenotypic plasticity. In Harpegnathos ants, adult workers can become queens via a caste transition that results in germline activation, lifespan extension, and major changes in behavior. This transition can be induced and reversed and offers a unique experimental paradigm to study the molecular regulation of behavioral and neuroanatomical plasticity. In the past ten years, we have sequenced the Harpegnathos genome, determined that all major epigenetic pathways are conserved and active in this organism, and have established various manipulation techniques,...

Speaker: Roberto Bonasio

Perelman School of Medicine University of Pennsylvania Philadelphia, PA

Host: Marzia Munafo` & Rahul Sureka

Place: Conf Room/Building 14

External Faculty Speaker

EMBL Rome

1 July 2022, 13:00

Investigating the native 3D ultrastructure of cells using soft X-rays and laser light

Speaker: Maria Harkiolaki

Diamond Light Source Ltd.

Host: Elizabeth Duke

Place: Seminar Room 48e

Hamburg Speaker

EMBL Hamburg

6 July 2022, 15:00

Prion Protein Biology Through the Lens of Liquid-Liquid Phase Separation: A Tale of an Intrinsically Disordered Tail

Speaker: Samrat Mukhopadhyay

Indian Institute of Science Education and Research (IISER)

Host: Toby Gibson

Place: Room 440

External Faculty Speaker

EMBL Heidelberg

15 July 2022, 11:00

To be announced

Speaker: Judith Hirsch

University of Southern California, Los Angeles, CA

Host: Santiago Rompani

Place: Conf Room/Building 14

External Faculty Speaker

EMBL Rome

31 August 2022, 14:00

Charting chromatin assembly at single-fiber resolution

Speaker: Vijay Ramani

Assistant Professor / Assistant Investigator Gladstone Institute for Data Science & Biotechnology UCSF Department of Biochemistry & Biophysics

Host: Arnaud Krebs and Michael Dorrity

Place: Large Operon

External Faculty Speaker

EMBL Heidelberg

2 September 2022, 13:00

To be announced

Speaker: Yves Gaudin

Institute for Integrative Biology of the Cell (I2BC), Gif-sur-Yvette,

Host: Kay Gruenewald(CSSB) and Matthias Wilmanns(CSSB)

Place: CSSB Auditorium DESY, Notkestraße 85, Building 15

Hamburg Speaker

EMBL Hamburg

16 September 2022, 13:00

To be announced

Speaker: Ben Engel

Helmholtz Zentrum Muenchen

Host: Kay Gruenewald (CSSB) & Matthias Wilmanns (EMBL)

Place: via Zoom VC

Hamburg Speaker

EMBL Hamburg

16 September 2022, 15:00

What Art can tell us about the Brain

Artists have been doing experiments on vision longer than neurobiologists. Some major works of art have provided insights as to how we see; some of these insights are so fundamental that they can be understood in terms of the underlying neurobiology. For example, artists have long realized that color and luminance can play independent roles in visual perception. Picasso said, "Colors are only symbols. Artists have been doing experiments on vision longer than neurobiologists. Some major works of art have provided insights as to how we see; some of these insights are so fundamental that they can be understood in terms of the underlying neurobiology. For example, artists have long realized that color and luminance can play independent roles in visual perception. Picasso said, "Colors are only symbols. Reality is to be found in luminance alone." This observation has a parallel in the functional subdivision of our visual systems, where color and luminance are processed by the evolutionarily newer, primate-specific What system, and the older, colorblind, Where (or How) system. Many techniques developed over the centuries by artists can be understood in terms of the parallel organization of our visual systems. I will explore how the segregation of color and luminance processing are the basis...

Speaker: Margaret Livingstone

Harvard Medical School, Boston, MA

Host: Santiago Rompani

Place: Virtual seminar

EMBL Distinguished Visitor Lecture

EMBL Rome

23 September 2022, 10:00

To be announced

Speaker: Karel Svoboda

Howard Hughes Medical Institute Janelia Research Campus Ashburn, VA

Host: Hiroki Asari

Place: Conf Room/Building 14

EMBL Distinguished Visitor Lecture

EMBL Rome

7 October 2022, 11:00

Somatic epigenetics mechanisms of stress allostasis and germ cell delivery of extracellular vesicles

Somatic epigenetics mechanisms of stress allostasis and germ cell delivery of extracellular vesicles Tracy L. Bale, N. Kanyuch, J. Chan, C. Morgan, N.A. Leu, S. Ament, M. Kane, C.N. Epperson Somatic epigenetics mechanisms of stress allostasis and germ cell delivery of extracellular vesicles Tracy L. Bale, N. Kanyuch, J. Chan, C. Morgan, N.A. Leu, S. Ament, M. Kane, C.N. Epperson Parental lifetime exposures to perturbations such as stress, infection, malnutrition, and advanced age have been linked with an increased risk for offspring disease, including a strong association with neurodevelopmental disorders. Our studies have focused on identifying the causal biological mechanisms whereby dynamic information in the environment can be transmitted by sperm to the point of conception. In our studies, we examine a causal role for somatic-to-germline transmission of stress information capable of altering fetal neurodevelopment via extracellular vesicles (EVs) in a preclinical model. Further, we have examined the somatic cells along the male reproductive tract able to generate...

Speaker: Tracy Bale

Center for Epigenetic Research in Child Health and Brain Development University of Maryland School of Medicine Baltimore, MD

Host: Cornelius Gross and Andrea Mele

Place: Sapienza Università di Roma - Aula Odeion - Museo dell'Arte Classica - P.le Aldo Moro, 5 - Roma

EMBL - Sapienza Lecture

EMBL Rome

14 October 2022, 11:00

Probabilistic and Epigenetic Underpinnings of Disease

Speaker: Andrew Pospisilik

Van Andel Institute Grand Rapids, MI

Host: Mathieu Boulard / Irene Bozzoni

Place: Sapienza Università di Roma - Aula Odeion - Museo dell'Arte Classica - P.le Aldo Moro, 5 - Roma

EMBL - Sapienza Lecture

EMBL Rome

21 October 2022, 11:00

RNA modifications: their function and role in cancer

Speaker: Tony Kouzarides

Milner Therapeutics Institute and Gurdon Institute University of Cambridge Cambridge

Host: Mathieu Boulard / Irene Bozzoni

Place: Sapienza Università di Roma - Aula Odeion - Museo dell'Arte Classica - P.le Aldo Moro, 5 - Roma

EMBL - Sapienza Lecture

EMBL Rome

28 October 2022, 13:00

To be announced

Speaker: Nassos Typas

EMBL Heidelberg Unit

Host: Kay Gruenewald ( CSSB) & Matthias Wilmanns( EMBL)

Place: CSSB Auditorium DESY, Notkestraße 85, Building 15

Hamburg Speaker

EMBL Hamburg

25 November 2022, 10:00

Epigenetic regulation in development and disease

Speaker: Alexander Meissner

Max Planck Institute for Molecular Genetics Berlin

Host: Jamie Hackett

Place: Conf Room/Building 14

EMBL Distinguished Visitor Lecture

EMBL Rome