Development

How single cells give rise to complex organisms

All the essential information on how a whole multicellular organism develops from a single cell is stored in that organism's genome and epigenome. Thousands of genes are switched on and off in a precisely coordinated manner.

A four-day-old mouse embryo
A four-day-old mouse embryo before it embeds itself in the womb. The cells that will make the connection to the womb are marked in blue. The cells that will give rise to the embryo are marked in orange, and the cells’ membranes are labeled in purple.

This enables individual cells to specialise in particular tasks and to arrange themselves into tissues and organs in the right locations. The developmental process is also influenced by environmental factors, such as the availability of nutrients.

Scientists at EMBL investigate the processes associated with embryo and organism development. They try to understand how embryos transition from a ball of identical cells to structured organisms with highly specialised tissues. The influence of mechanical stimuli and environmental factors on development are also investigated. EMBL scientists try to understand how biological rhythms create waves of activity of genes or signalling molecules, which helps to establish regular structures and tells organs where to form. Alongside traditional lab methods, bioinformatics approaches are also used to explore the processes of development.


EMBL units researching development

Developmental biology

Scientists in the Developmental biology unit seek to understand the fundamental principles that govern multicellular development.

Genome biology

The Genome biology unit uses and develops cutting-edge methods to study how the information in our genome is regulated, processed, and utilised, and how its alteration leads to disease.

Tissue biology and disease modelling

Scientists at EMBL Barcelona use advanced technologies to observe, manipulate, and model how changes in genes percolate through cells, tissues, and organs, in health and disease.

View all EMBL research units


Database Engineer

Technology in EMBL-EBI Hinxton

About the TeamThe Database team at EMBL-EBI provides day-to-day database administration support, performance tuning and query optimisation for the production, development and test database environments operated by our end users (the bioinformatics, technical and research teams of EMBL-EBI). The larg...

Closes on 6th February. Posted 13th January 2026

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Senior Platform Developer

Technology in EMBL-EBI Hinxton

About the TeamWould you like to build the foundations of great services used by researchers from around the world to interrogate and explore genomic data? Are you interested in a technical role that shapes and improves the infrastructure behind some of the World’s most widely used scientific data re...

Closes on 6th February. Posted 5th January 2026

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Postdoctoral Fellow - Pandemic-scale Phylodynamics

Science, research and training in EMBL-EBI Hinxton

Your groupThe Goldman group at EMBL-EBI (https://www.ebi.ac.uk/research/goldman/) develops methods for improving sequencing technologies and bioinformatics analyses. We often devise new algorithms, mathematical models, and approximations, and use them to process large genomic datasets. The group is...

Closes on 19th January. Posted 23rd December 2025

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Inklusionshilfe (m/w/d) – EMBL Kinderhaus (Kindergarten Gruppe, Midi Job)

Science, research and training in EMBL Heidelberg

Wie in allen anderen Bereichen strebt das EMBL danach, auch der Forschungsverwaltung Modellcharakter zu verleihen. Der EMBL Kindergarten betreut als Betriebskindertagesstätte ganztägig bis zu 128 Kinder im Alter von 3 Monaten bis 6 Jahren in 10 Gruppen. Wir bieten motivierten und engagierten Erziehe...

Closes on 31st January. Posted 23rd December 2025

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From microscopy to mycology, from development to disease modelling, EMBL researchers cover a wide range of topics in the biological sciences.