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cryo-EM

Simone Mattei, the new team leader in electron microscopy service and technology development

Welcome: Simone Mattei

The new team leader offering services in electron microscopy discusses his hopes and plans for the forthcoming EMBL Imaging…

By Edward Prior

Lab Matters

Four tree-like proteins in red, orange, blue and grey on a white membrane surface. The proteins are dotted with short green chains.

Flexible and protected – new findings on SARS-CoV-2 protein shed light on virus’s ability to infect cells

Researchers studied the spike protein on the surface of the SARS-CoV-2 virus. With its spikes, the virus binds to human cells and infects them. The…

By Mathias Jäger

Science

This visual representation shows the newly identified architecture (left) of the coupled molecular machines responsible for transcription (green; DNA in magenta) and translation (blue and yellow), accompanied by the protein interaction network from mass spectrometry (centre) and the cryo-electron tomography data (right) from Mycoplasma pneumoniae that was used to model the structure. Credit: Liang Xue and Julia Mahamid/EMBL

Visualising the cell’s molecular machinery in action

A new approach that allows researchers to see molecular machinery at work inside cells has offered a deeper understanding of how bacteria produce…

By Ivy Kupec

Science

Atomic model of the entire condensin complex

Understanding chromosome organisation

EMBL scientists and collaborators help reveal the process by which enormous quantities of DNA are folded into…

By Edward Prior

Science

Crystal selection for X-ray diffraction experiments.

Investigating the structure and mechanisms of coronavirus biomolecules

While global research on coronaviruses has shed light on the function of many SARS-CoV-2 proteins, the role of some crucial components remains…

By Adam Gristwood

Science

The Influenza virus

Understanding the influenza virus

The infectious disease commonly known as flu is caused by the influenza virus. It spreads around the world in seasonal outbreaks, causing millions of…

By Fabian Oswald

Science

Supporting international research on the structure of the coronavirus

EMBL Heidelberg reopens the Cryo-Electron Microscopy Service Platform to support coronavirus structural biology…

By Anne-Marie Alleaume

Science

Structure of the Elongator complex

A tRNA modifier at work

Using cryo-EM, scientists have determined the structure of a large protein complex called…

By Cella Carr

Science

An example virtual map of individual leukaemia cells on a resin section, detected automatically using SerialEM and py-EM.

Breaking the bottleneck in imaging data collection

Scientists develop software tools for automated acquisition of electron microscopy…

By Cella Carr

Science

Surface views of 3D reconstructions of the TBEV sub-viral particles.

Translating blue-sky research into the clinic

What does it take to create a vaccine or improve cancer…

By Emma Steer

Lab Matters

Insulin receptor structural biology. IMAGE: Felix Weis and Christoph Müller / EMBL

More effective insulin thanks to first 3D image

New study reveals how to make therapeutic insulins more effective than they currently…

By Iris Kruijen

Science

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