Edit

cryo-EM

This visual representation shows the newly identified architecture (left) of the coupled molecular machines responsible for transcription (green; DNA in magenta) and translation (blue and yellow), accompanied by the protein interaction network from mass spectrometry (centre) and the cryo-electron tomography data (right) from Mycoplasma pneumoniae that was used to model the structure. Credit: Liang Xue and Julia Mahamid/EMBL

Visualising the cell’s molecular machinery in action

A new approach that allows researchers to see molecular machinery at work inside cells has offered a deeper understanding of how bacteria produce proteins and a unique glimpse into how they respond to antibiotics.

By Ivy Kupec

Science

Atomic model of the entire condensin complex

Understanding chromosome organisation

EMBL scientists and collaborators help reveal the process by which enormous quantities of DNA are folded into cells.

By Edward Prior

Science

Crystal selection for X-ray diffraction experiments.

Investigating the structure and mechanisms of coronavirus biomolecules

While global research on coronaviruses has shed light on the function of many SARS-CoV-2 proteins, the role of some crucial components remains unknown. Researchers at EMBL Grenoble will use a range of structural biology methods to try to solve some of the puzzles of the molecular mechanics of…

By Adam Gristwood

Science

The Influenza virus

Understanding the influenza virus

The infectious disease commonly known as flu is caused by the influenza virus. It spreads around the world in seasonal outbreaks, causing millions of infections and hundreds of thousands of deaths each year. Stephen Cusack, Head of EMBL Grenoble, has been studying different aspects of the influenza…

By Fabian Oswald

Science

Supporting international research on the structure of the coronavirus

EMBL Heidelberg reopens the Cryo-Electron Microscopy Service Platform to support coronavirus structural biology research.

By Anne-Marie Alleaume

Science

Cryo-ET and micropatterning

Photo-micropatterning advances structural cell biology

A new technique in cryo-EM

By Cella Carr

Science

Structure of the Elongator complex

A tRNA modifier at work

Using cryo-EM, scientists have determined the structure of a large protein complex called Elongator.

By Cella Carr

Science

An example virtual map of individual leukaemia cells on a resin section, detected automatically using SerialEM and py-EM.

Breaking the bottleneck in imaging data collection

Scientists develop software tools for automated acquisition of electron microscopy data

By Cella Carr

Science

Surface views of 3D reconstructions of the TBEV sub-viral particles.

Translating blue-sky research into the clinic

What does it take to create a vaccine or improve cancer therapies?

By Emma Steer

Lab Matters

Insulin receptor structural biology. IMAGE: Felix Weis and Christoph Müller / EMBL

More effective insulin thanks to first 3D image

New study reveals how to make therapeutic insulins more effective than they currently are

By Iris Kruijen

Science

EMBLetc.

Read the latest Issues of our magazine - EMBLetc.

Looking for past print editions of EMBLetc.? Browse our archive, going back 20 years.

EMBLetc. archive
Edit