Technology and innovation Enzymes constitute a large fraction of genomes – 20% in humans – which makes them a very important part of life. Despite decades of studies and a rich literature dedicated to understanding the reaction mechanisms of enzymes, the rules of enzyme catalysis are still not fully clear. A new…
2023
technology-and-innovation
Announcements, Lab Matters David Hulcoop discusses how his experience bridging organisational cultures will help address critical challenges in drug discovery and target selection at Open Targets.
2023
announcementslab-matters
Announcements Coming from a pharmaceutical industry background, David Hulcoop is set to take over as Executive Director of the public-private partnership Open Targets.
2023
announcements
Science, Technology and innovation A new tool for the interpretation of missense variation in humans – ProtVar – will help enable drug discovery.
2023
sciencetechnology-and-innovation
Announcements, Lab Matters EMBL-EBI is making a key contribution to a historic effort to understand the function of every human gene
2023
announcementslab-matters
Research highlights, Science Researchers create a network of interacting proteins – or interactome – to aid drug discovery.
2023
research-highlightsscience
Lab Matters EMBL is one of the partners of this project that aims to accelerate drug discovery and development, bringing in expertise from EMBL Grenoble and EMBL-EBI.
2023
lab-matters
Science, Technology and innovation Open Targets is using artificial intelligence and machine learning to identify and prioritise drug targets.
2023
sciencetechnology-and-innovation
Announcements, Science Open Targets, a consortium focused on drug target identification, prioritisation, and validation, announced today that Pfizer has joined as a partner.
2022
announcementsscience
Lab Matters Ian Dunham walks us through his career so far including working on the human genome project, seeing his work on the cover of Nature and his current role as Director of Open Targets.
2021
lab-matters
Events EMBL will host a conference to look at the state of the pandemic, lessons learned, and ways to improve pandemic preparedness. Here’s a sneak peek into what promises to be another interesting and informative EMBL conference.
2021
events
Science Researchers establish a framework for identifying new drugs capable of exploiting a cell’s own machinery.
2021
science
Science EMBL Hamburg’s integrated structural biology facility has contributed to the success of a large-scale SARS-CoV-2 study
2021
science
Science Researchers use large-scale human genetic studies to identify drug targets important for managing COVID-19 in its early stages
2021
science
Science Scientists from the Beltrao Group at EMBL-EBI and collaborators identified drug targets common to SARS-CoV-2, SARS-CoV-1, and MERS-CoV, three pathogenic coronaviruses. They also found potential drugs that could be repurposed as COVID-19 treatments, and against emerging coronavirus strains in the…
2020
science
Events The virtual EMBL Conference ‘SARS-CoV-2: Towards a New Era in Infection Research’ explored the importance of fundamental research, collaboration, and data science in containing the SARS-CoV-2 pandemic, and discussed opportunities to improve our response to pandemics in the future.
2020
events
Lab Matters Open Targets welcomes new Informatics Science Director
2020
lab-matters
Science The infectious disease commonly known as flu is caused by the influenza virus. It spreads around the world in seasonal outbreaks, causing millions of infections and hundreds of thousands of deaths each year. Stephen Cusack, Head of EMBL Grenoble, has been studying different aspects of the influenza…
2020
science
Events EMBL Hamburg and Tara raise awareness of the risks of microplastic pollution and global infection
2019
events
Science Large CRISPR screen prioritises hundreds of promising genes for personalised cancer treatment
2019
science
Lab Matters New director drives drug discovery partnership forward
2019
lab-matters
Lab Matters Pharmaceutical company Sanofi strengthens drug targets discovery collaboration Open Targets
2018
lab-matters
Lab Matters EMBL and Promega collaborate to train young scientists
2018
lab-matters
Lab Matters New partner strengthens drug discovery collaboration
2018
lab-matters
Science ERC grantee Stephen Cusack shares his vision for the next ten years
2017
science
Lab Matters Takeda joins pioneering public-private drug discover collaboration Open Targets
2017
lab-matters
Alumni Alumnus Michael Parker talks about his career, research highlights and how EMBL has played a role
2017
alumni
Science Q&A with EMBL-EBI's Head of Chemical Biology data services
2017
science
Science ERC grantee Maja Köhn shares her vision for the next ten years
2017
science
Science EMBL scientists add crucial knowledge to understanding of the bacterium that causes tuberculosis
2017
science
Lab Matters Pioneering target validation collaboration expands to accelerate drug discovery research.
2016
lab-matters
Science Mature cells can be reprogrammed to pluripotency and thus regain the ability to divide and differentiate into specialized cell types. Although these so-called induced pluripotent stem cells (iPS cells) represent a milestone in stem cell research, many of the biochemical processes that underlie…
2013
science
Science ChEMBLdb, a vast online database of information on the properties and activities of drugs and drug-like small molecules and their targets, launches today with information on over half a million compounds. The data lie at the heart of translating information from the human genome into successful new…
2010
science
Lab Matters The Wellcome Trust has awarded £4.7 million (€5.8 million) to EMBL’s European Bioinformatics Institute (EMBL-EBI) to support the transfer of a large collection of information on the properties and activities of drugs and a large set of drug-like small molecules from the publicly listed…
2008
lab-matters
Lab Matters Today EMBL scientists, EMBL’s commercial affiliate, EMBL Enterprise Management Technology Transfer GmbH (EMBLEM) and EMBL’s venture vehicle, EMBL Ventures GmbH, announce the foundation of Elara Pharmaceuticals GmbH, a start-up company that will translate basic research findings into new…
2006
lab-matters
Science Tuberculosis remains one of the deadliest threats to public health. Every year two million people die of the disease, which is caused by the microorganism Mycobacterium tuberculosis. Roughly one third of the world’s population is infected and more and more bacterial strains have developed…
2006
science
Science A detailed structural picture of a molecule that plays a key role in activating the Epstein Barr Virus in human cells has now been obtained by researchers at the European Molecular Biology Laboratory (EMBL) and the Institut de Virologie Moléculaire et Structurale (IVMS), associated with the…
2006
science
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