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mrna

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19 December 2023 Cartoon showing nanoparticles on a conveyer belt passing through a machine. They are ordered by size and the smallest one pass through the machine before the bigger ones. A ray of light enters the machine, where a nanoparticle is being scanned, and leaves it on the other side. A monitor on top of the scanning machine shows an X-ray of a nanoparticle.

‘X-ray vision’ for investigation of mRNA nanomedicines

Science EMBL Hamburg, Johannes Gutenberg University Mainz, Postnova Analytics GmbH, and BioNTech SE have developed a new method to quantitatively investigate sizes of nanoparticles containing mRNA. It may become an important part of regular characterisation of mRNA nanomedicines in the future.

2023

science

2 October 2023 Outline of a human, purple against red background. Red RNA strand in the background, electrocardiogram across the image. On the right, outline of a Nobel prize medal.

mRNA nanomedicines scoop Nobel Prize in Physiology or Medicine

Science Pioneers of the mRNA nanomedicines technology receive 2023 Nobel Prize in Physiology or medicine. EMBL is pleased to have supported the development of the application of the mRNA nanomedicine technology through our long-standing collaboration with BioNTech, Johannes Gutenberg University Mainz and…

2023

science

24 August 2023 Set against a blue background, an illustration of a small paper shredder seemingly works at shredding mRNA, often in the form of origami shapes that float nearby.

Deciding when to destroy mRNA

Alumni Elena Conti will discuss how cells control the life and death of mRNA molecules at the next annual Kafatos Lecture on 20 October in Munich.

2023

alumni

9 June 2020 This image shows the structure of a bacterial group II intron

Genetic cut and paste at atomic resolution

Science Researchers in the Marcia group at EMBL Grenoble and the De Vivo lab at the Italian Institute of Technology in Genoa have obtained some of the most detailed ever snapshots of the splicing process in systems known as group II self-splicing introns. The new insights will help scientists to develop…

2020

science

4 February 2009 High resolution image of the key domain of the influenza virus polymerase. The active site responsible for RNA cleavage is shown in red. Its activity is crucial for the virus to multiply in human cells

New findings reveal how influenza virus hijacks human cells

Science Influenza is and remains a disease to reckon with. Seasonal epidemics around the world kill several hundred thousand people every year. In the light of looming pandemics if bird flu strains develop the ability to infect humans easily, new drugs and vaccines are desperately sought. Researchers at…

2009

science

4 May 2008

Getting wise to the influenza virus’ tricks

Science Influenza is currently a grave concern for governments and health organisations around the world. Now one of the tactics used by influenza virus to take over the machinery of infected cells has been laid bare by structural biologists at the EMBL, the joint Unit of Virus Host-Cell Interaction of…

2008

science

16 May 2007

Mechanism of microRNAs deciphered

Science Over 30% of our genes are under the control of small molecules called microRNAs. They prevent specific genes from being turned into protein and regulate many crucial processes like cell division and development, but how they do so has remained unclear. Now researchers from the European Molecular…

2007

science

25 August 2005

A double punch for female survival

Science Achieving equality between the sexes can be a challenge even for single cells. Since evolution began removing bits of male DNA to create the ‘Y’ chromosome, males have had a single copy of certain key genes on the X chromosome, whereas females have two. Normally this would lead females…

2005

science

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