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Korbel

EMBL boosts national and international sharing of genomic data

A national consortium including EMBL and the DKFZ is set to launch the German Human Genome–Phenome Archive, creating an invaluable bridge between fundamental biomedical research and applied healthcare.…

By Jodie Haigh

Lab Matters

77% of the life science institutes are shut down. 57% of the asked scientists lost up to 6 months of work. 66% use the extra time for career development. 18% now take part in COVID-19 research. 30% have so far attended a virtual conference.

EMBL survey studies effects of COVID-19 pandemic on life scientists

Jan Korbel and Oliver Stegle have performed a survey of fellow life scientists to learn how the current crisis, with partial or complete institutional shutdowns, is affecting their work.…

By Mathias Jäger

Lab Matters

Close-up photograph of servers at EMBL Heidelberg's data centre.

Understanding the role of our genes in SARS-CoV-2 infections

EMBL scientists will contribute to the new German COVID-19 OMICS Initiative to study the biological mechanisms contributing to coronavirus infections. EMBL group leaders Jan Korbel and Oliver Stegle, who is also affiliated with the DKFZ Heidelberg, will coordinate the set-up of IT infrastructures…

By Marius Bruer

Science

Understanding brain tumours in children

The causes of 40 percent of all cases of certain medulloblastoma – dangerous brain tumours affecting children – are hereditary. These are the findings of a recent genetic analysis carried out by scientists from EMBL and numerous colleagues around the world.…

By Mathias Jäger

Science

The Pan-Cancer project

EMBL co-leads most comprehensive study of genetic causes of cancer…

By Mathias Jäger

Science

Analysis of human genomes in the cloud

Scientists from EMBL present a tool for large-scale analysis of genomic data with cloud computing. Main advantages of the new tool, called Butler, are continuous system monitoring and its ability to self-heal in case of failure, allowing for 43% more efficient data processing than previous…

By Mathias Jäger

Science

Finding genetic cancer risks

Using the data from the Pan-Cancer project EMBL scientists describe how our genetic background influences cancer development.…

By Fabian Oswald

Science

EMBL co-develops new method that could facilitate cancer diagnosis

Researchers have developed a cheaper and faster method to check for genetic differences in individual cells…

By Mathias Jäger

Science

The pyramids represent chromatin domains in the wild-type situation. The reflection in the water below represents the rearrangements in the mutant fruit fly chromosomes. At first glance the (regulatory) landscapes look very similar, but there are lots of changes to the topology, and yet these have little impact on the nature of the landscape (gene expression). IMAGE: Beata Edyta Mierzwa in collaboration with EMBL.

Rearranging chromosomes

Does rearranging chromosomes affect their function? EMBL scientists reveal uncoupling of 3D chromatin organisation and gene expression.…

By Iris Kruijen

Science

IMAGE: Korbel group/EMBL

Catalogue of structural variants

Thorough characterisation of structural variants in human genomes…

By Guest author(s)

Science

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