New project to improve understanding of gene regulation landscape
EMBL-EBI and leading UK universities will use zebrafish to study interaction and coordination between gene enhancers in the genome
2025
announcements
New tool offers single-cell study of specific genetic variants
EMBL scientists have developed a more sensitive single-cell sequencing tool that links genomic variants and RNA in the same cell, helping to better uncover links to complex diseases.
SCIENCE & TECHNOLOGY2025
science-technology
Speaking the language of DNA
Right from the early days of DNA sequencing, EMBL’s scientists have been instrumental in helping the world understand, decode, archive, and manipulate genomes at scale and across many branches of the evolutionary tree, a task they continue to excel at today.
SCIENCE & TECHNOLOGY2024
science-technology
Ensembl 113 and Ensembl Genomes 60 have been released
Ensembl 113 brings major gene and regulatory feature annotation updates in Homo sapiens (human) and Mus musculus (mouse).
2024
updates-from-data-resources
Casting new light on gene regulation in development
New research from EMBL Heidelberg shows how cells in developing embryos undergo a major shift in the way they regulate gene expression as they mature and differentiate.
SCIENCE & TECHNOLOGY2024
sciencescience-technology
How AI shapes the life sciences: an interview with Oliver Stegle
EMBL scientist Oliver Stegle explains how AI-based tools have the potential to transform our ability to better understand the complexity of life and how these tools will shape the future of life science exploration.
LAB MATTERSPEOPLE & PERSPECTIVES2023
lab-matterspeople-perspectives
Ensembl Bacteria releases new annotation for all its genomes
Ensembl 110 and Ensembl Genomes 57 have introduced in-house prokaryotic gene annotation across genomes available in Ensembl Bacteria. Since its inception, Ensembl Bacteria has imported user-submitted annotations from the International Nucleotide Sequence Database Collaboration (INSDC) for…
2023
updates-from-data-resources
New therapies to improve cardiovascular health
EMBL researchers have made new strides into understanding and reversing genetic defects that underlie familial heart disease.
SCIENCE & TECHNOLOGY2023
sciencescience-technology
refget v2.0 links the hidden dictionaries of DNA
The GA4GH standard refget quietly helps decipher millions of genomes sequenced worldwide, and it just got better.
2023
technology-and-innovation
The power of cell sorting: understanding heart disease, phase separation, plankton, and more
EMBL researchers use a new cell sorting technology to gain new insights into cellular function in health and disease, as well as for other innovative applications.
SCIENCE & TECHNOLOGY2023
sciencescience-technology
The ‘long read’ for cancer
Using Oxford Nanopore long-read sequencing, EMBL scientists sequenced a primary childhood brain tumour known as a medulloblastoma, uncovering a novel complex mutation pattern.
2023
science
Open data for biodiversity: an EMBL-EBI 2022 round-up
As major biodiversity projects ramp up, EMBL-EBI enables genomic data sharing for all species.
2023
perspectivesscience
EMBL builds on links with Malta
EMBL deepens scientific collaboration, opening the door for greater engagement and opportunities for Malta’s life science community
CONNECTIONS2022
connectionsevents
Zooming in to get the full picture
EMBL and UW researchers plus additional collaborators have constructed a complete map of fruit fly embryonic development using machine learning. This research is foundational to better understanding overall embryo development in other species, including humans.
SCIENCE & TECHNOLOGY2022
sciencescience-technology
Supporting the African BioGenome Project to build bioinformatics capacity
The African BioGenome Project and EMBL have signed a Memorandum of Understanding to support each other in building genomics and bioinformatics capacity across Africa
CONNECTIONSLAB MATTERS2022
announcementsconnectionslab-matters
A machine learning approach for allocating gene function
Researchers in the Ensembl team are making the most of machine learning methods to speed up genome annotation pipelines
SCIENCE & TECHNOLOGY2022
sciencescience-technologytechnology-and-innovation
Converging lenses on embryo development
Researchers from the Furlong group at EMBL have come up with a way to observe the development of fruit-fly embryos simultaneously at the genetic and cellular levels, generating a high-resolution and integrated view of how different cell lineages form.
SCIENCE & TECHNOLOGY2022
sciencescience-technology
Cell sorting enters a new dimension
EMBL researchers, in collaboration with BD Biosciences, have demonstrated a new technology that allows rapid image-based sorting of cells. The new technology represents a major upgrade to flow cytometry and has applications in diverse life science fields.
SCIENCE & TECHNOLOGY2022
sciencescience-technology
The Earth Biogenome Project: on track and ready to ramp up
On track to reach an ambitious goal of 3,000 genomes sequenced by the end of 2022, what’s next for the Earth Biogenome Project?
SCIENCE & TECHNOLOGY2022
announcementssciencescience-technology
Eileen Furlong honoured with Leibniz Prize
EMBL Senior Scientist and Head of the Genome Biology Unit is among the researchers honoured for outstanding work by the German Research Foundation (Deutsche Forschungsgemeinschaft, DFG).
EMBL ANNOUNCEMENTSLAB MATTERS2021
embl-announcementslab-matters
Welcome: Maria Zimmermann-Kogadeeva
Maria Zimmermann-Kogadeeva is one of EMBL’s newest group leaders and a computational biologist whose research group applies computational modelling to better understand the metabolism of gut bacteria and their potential to have far-reaching impacts on other organs.
LAB MATTERSPEOPLE & PERSPECTIVES2021
lab-matterspeople-perspectives
Tackling the collateral damage from antibiotics
Researchers from EMBL’s Typas group and collaborators have analysed the effects of 144 antibiotics on the wellbeing of gut microbes. The study improves our understanding of antibiotics’ side effects and suggests a new approach to mitigating the adverse effects of antibiotics therapy on gut…
SCIENCE & TECHNOLOGY2021
sciencescience-technology
New insights into Salmonella’s survival strategies
Research in the Typas group uncovers new details of the strategies Salmonella uses to survive in infected cells.
SCIENCE & TECHNOLOGY2021
sciencescience-technology
Welcome: Sarah Dyer
EMBL welcomes Sarah Dyer, the new Non-Vertebrate Genomics Team Leader at EMBL-EBI.
LAB MATTERSPEOPLE & PERSPECTIVES2021
lab-matterspeople-perspectives
Food safety, antibiotics, and a shrinking planet
After work in antimicrobial resistance, EMBL postdoc Laura Carroll is using machine learning for next-gen antibiotic development.
PEOPLE & PERSPECTIVES2021
people-perspectivesscience
Piecing together the best reference genome
Researchers reveal the best technology for assembling reference genomes.
SCIENCE & TECHNOLOGY2021
sciencescience-technology
Welcome: Sinem Saka
As one of EMBL’s newest group leaders, Sinem Saka will combine multiple technologies, such as microscopy and single-cell omics, to solve biological puzzles.
LAB MATTERSPEOPLE & PERSPECTIVES2021
lab-matterspeople-perspectives
Finding coronavirus’s helper proteins
A team of EMBL scientists and colleagues have analysed how the novel coronavirus affects proteins in human cells. They identified several human proteins as potential drug targets to prevent viral replication.
SCIENCE & TECHNOLOGY2021
sciencescience-technology
Heating proteins to understand how genes work
A new paper from EMBL’s Savitski team and Typas group describes their work on E. coli and how it brings a greater understanding of the way genes function and interact.
SCIENCE & TECHNOLOGY2020
sciencescience-technology
Predicting how gene expression varies
Discoveries at EMBL will help researchers to interpret one of the most common types of experiments in genomics and medical studies.
SCIENCE & TECHNOLOGY2020
sciencescience-technology
Enabling functional genomics studies in individual cells
Scientists at EMBL Heidelberg have developed a new method, called Targeted Perturb-seq (TAP-seq), which increases the scale and precision of functional genomics CRISPR–Cas9 screens by orders of magnitude. Their method overcomes limitations in previous applications of single-cell RNA sequencing,…
SCIENCE & TECHNOLOGY2020
sciencescience-technology
EMBL hosts its first virtual conference
The virtual EMBO | EMBL symposium ‘The Four-Dimensional Genome’ brought together 470 participants. Here, Jürgen Deka, Head of External Scientific Training, discusses how he and his team overcame the organisational challenges.
LAB MATTERS2020
eventslab-matters
New insights into gene regulation
EMBL researchers investigate the role of a histone protein in regulating gene expression
SCIENCE & TECHNOLOGY2020
sciencescience-technology
ATP affects proteome-wide solubility
Scientists develop technology to measure how ATP concentration affects protein solubility in cells
SCIENCE & TECHNOLOGY2019
sciencescience-technology
Exploring genetic variation
EMBL group leader Jan Korbel reflects on his scientific origins and current research
SCIENCE & TECHNOLOGY2018
sciencescience-technology
How drugs affect the life and death of proteins
Scientists at EMBL and Cellzome develop technology to monitor the effects of drug treatments on protein degradation and synthesis
SCIENCE & TECHNOLOGY2018
sciencescience-technology
Life and death of proteins
EMBL scientists create a turnover catalogue of almost 10.000 proteins from primary cells
SCIENCE & TECHNOLOGY2018
sciencescience-technology
Welcome: Arnaud Krebs
EMBL’s new group leader studies how gene expression is controlled
PEOPLE & PERSPECTIVES2018
people-perspectivesscience
Multipurpose enhancers and promoters in embryonic development
EMBL scientists show that some promoters can act as enhancers and vice versa
SCIENCE & TECHNOLOGY2018
sciencescience-technology
Curious genomes
What are the strangest genomes in EMBL-EBI's Ensembl?
SCIENCE & TECHNOLOGY2017
sciencescience-technology
Bridging excellence: EMBL and Stanford’s Alliance
Lars Steinmetz. Director of the Life Science Alliance, reflects on the EMBL|Stanford initiative
CONNECTIONS2017
connectionsevents
Embryos use ancient viral DNA
EMBL scientists detect important function of genetic sequence our ancestors assimilated from a virus
SCIENCE & TECHNOLOGY2017
sciencescience-technology
Blood stem cell differentiation is continuous
Study by EMBL and DKFZ researchers means origins of myeloid leukaemias may need rethinking
SCIENCE & TECHNOLOGY2017
sciencescience-technology
The human genome’s breaking points
A detailed analysis of data from 185 human genomes sequenced in the course of the 1000 Genomes Project, by scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, in collaboration with researchers at the Wellcome Trust Sanger Institute in Cambridge, UK, as well as the…
SCIENCE & TECHNOLOGY2011
sciencescience-technology
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