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Coronavirus

Bioinformatic analysis of over 4700 SARS-CoV-2 genomes revealed that many of the most interesting changes in the SARS-CoV-2 genome that have been reported so far are likely to be technical artefacts, rather than biological mutations.

Distinguishing coronavirus genome mutations from inadvertent errors

EMBL scientists have performed a large-scale analysis of over 4700 SARS-CoV-2 genome sequences. They found that many of the most interesting changes in the SARS-CoV-2 genome that have been reported so far are likely to be technical artefacts, rather than biological mutations.…

By Marius Bruer

Science

The hunt for neutralising antibodies against SARS-CoV-2

Scientists hope that a legacy of the novel coronavirus in recovered COVID-19 patients – antibodies in their blood – could lead to drugs to treat others. The Merten group at EMBL Heidelberg has pivoted its microfluidics platform to support the search for neutralising antibodies that could…

By Adam Gristwood

Science

Close-up photograph of servers at EMBL Heidelberg's data centre.

Understanding the role of our genes in SARS-CoV-2 infections

EMBL scientists will contribute to the new German COVID-19 OMICS Initiative to study the biological mechanisms contributing to coronavirus infections. EMBL group leaders Jan Korbel and Oliver Stegle, who is also affiliated with the DKFZ Heidelberg, will coordinate the set-up of IT infrastructures…

By Marius Bruer

Science

EMBL SPC facility supports COVID-19 projects

The Sample Preparation and Characterisation Facility (SPC) at EMBL Hamburg reopens to support scientists working on Covid-19 research. The SPC Facility is one of the best equipped facilities in Europe is therefore in high demand from external users. Re-opening the facility also allows experts at…

By Sara Verstraeten

Science

Liquid handling robot transfering protein crystalisation solutions

Responding to health threats posed by coronaviruses

By re-opening the High-Throughput Crystallisation (HTX) lab at EMBL Grenoble, EMBL is supporting structural biology projects to respond to the health threats posed by coronaviruses.…

By Sara Verstraeten

Science

Crystallization reagents being prepared by a pipetting robot at the HTX lab.

Remote access to EMBL structural biology pipelines to support research on SARS-CoV-2

The Marquez Team has restarted operations at the High-Throughput Crystallisation (HTX) lab at EMBL Grenoble. The team has developed a fully automated protein-to-structure pipeline, which can be operated remotely and provides virtual access to the facilities.…

By Sara Verstraeten

Science

Laboratory Officer Nicole Schieber working in EMBL's Electron Microscopy Core Facility. PHOTO: Viola Oorschot/EMBL

Taking a closer look at infected cells to better understand COVID-19

EMBL electron microscopy specialists collaborate with researchers from Heidelberg University Hospital to understand the changes occurring in cell structures upon SARS-CoV-2 infection.…

By Anne-Marie Alleaume

Science

Close-up view of the interior of a protein analytics system

Exploring synthetic antibodies to stop coronavirus

Scientists at EMBL Hamburg and Karolinska Institutet Stockholm aim to find synthetic antibodies – known as nanobodies – that bind a surface protein of the novel SARS-CoV-2 coronavirus. Nanobodies could prevent the virus from entering human cells and causing COVID-19.…

By Marius Bruer

Science

Artistic rendering of an RNA-binding protein interacting with an RNA molecule.

Helping researchers identify host proteins used by coronavirus

EMBL scientists working in the groups of Matthias Hentze and Wolfgang Huber have created RBPbase – a database of RNA-binding proteins – to assist the identification of proteins that interact with the SARS-CoV-2 RNA genome.…

By Marius Bruer

Science

Collage of images representing wet and dry lab research and healthcare

Why share data during a pandemic?

In March 2020, planes were grounded, streets went quiet, and our lives changed forever. But while the world came to a halt, many scientists were ramping up their efforts to understand the new virus.…

By Oana Stroe

Science

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