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Chromosome Archives | EMBL

Chromothripsis in human cancer

Researchers at Harvard Medical School and EMBL-EBI have carried out the largest analysis across cancer types of the newly discovered mutational phenomenon chromothripsis.

By Vicky Hatch

Science

Reshaping our DNA

DNA is present in each cell of our body. If all the DNA from one human cell was removed and aligned in a single strand, it would in theory add up to a total length of about two metres. In order to fit into the nucleus of a cell, DNA has to be compressed by […]

By Doreen Feike

Picture of the week

Stripes of colour display gene expression patterns

Transcriptional hubs confer phenotypic robustness

Enhancers in Drosophila embryos gather together to preserve phenotypes under stressful conditions

By Josh Tapley

Science

Structural biology image of the condensin complex.

Intact chromosomes during cell division

The mystery of how condensin maintains the integrity of the genome during cell division. 

By Patrick Mueller

Science

Year 2018 standing on library shelf

Most popular articles of the year: 2018

A collection of the most read articles from the EMBL news website in 2018

By Josh Tapley

Lab Matters

During cell division, cohesin directly engages DNA (purple) and holds the replicated chromosome together. IMAGE: Nasser Rusan/National Institutes of Health

Cohesin: a glue for DNA

EMBL scientists discover how a component of the cohesin ring binds DNA

By Patrick Mueller

Science

New EMBL group leader Simone Köhler.

Welcome: Simone Köhler

Which of our genes will be passed on to our children? Simone Köhler wants to find out

By Emma Steer

Science

In this image of developing cells, fluorescent molecules reveal DNA (blue), part of the X chromosomes (red), and the Xist RNA (white). The green colour shows a region of the cells’ nuclei called the nuclear lamina. IMAGE: Mikael Attia and Edith Heard/Institut Curie

The scientific origins of Edith Heard

EMBL’s next Director General reflects on the questions that drive her research

By Guest author(s)

Science

Melina Schuh has received an EMBO Gold Medal for outstanding contributions to the life sciences in Europe.

Melina Schuh receives EMBO Gold Medal

EMBL alumna Melina Schuh recognised for excellence in science

By Guest author(s)

Alumni

As a cell prepares to divide, the chromosomes (shown here in pink) condense, becoming more tightly coiled and easier to observe under the microscope. The faint structure in the centre is a cell nucleus in which the chromosomes are in their usual decondensed state.

Exploring genetic variation

EMBL group leader Jan Korbel reflects on his scientific origins and current research

By Edward Dadswell

Science

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