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Chromosome

Dancing chromosomes

In human cells, the genetic material is packaged into 23 different DNA molecules, the chromosomes. Each chromosome is present in two copies, one inherited from the paternal sperm, and the other from the maternal egg. During most of the cell’s life, chromosomes take the shape of long,…

By Mehdi Khadraoui

Picture of the week

3D reconstruction of parental chromosomes in the mouse embryo

How chromosome structure influences development

EMBL researchers in the Heard group at EMBL Heidelberg explore the interaction between DNA organisation and gene expression in the early embryo…

By Fabian Oswald

Science

Chromothripsis in human cancer

Researchers at Harvard Medical School and EMBL-EBI have carried out the largest analysis across cancer types of the newly discovered mutational phenomenon chromothripsis.…

By Vicky Hatch

Science

Reshaping our DNA

DNA is present in each cell of our body. If all the DNA from one human cell was removed and aligned in a single strand, it would in theory add up to a total length of about two metres. In order to fit into the nucleus of a cell, DNA has to be compressed by […]…

By Doreen Feike

Picture of the week

Stripes of colour display gene expression patterns

Transcriptional hubs confer phenotypic robustness

Enhancers in Drosophila embryos gather together to preserve phenotypes under stressful conditions…

By Josh Tapley

Science

Structural biology image of the condensin complex.

Intact chromosomes during cell division

The mystery of how condensin maintains the integrity of the genome during cell division. …

By Patrick Mueller

Science

Year 2018 standing on library shelf

Most popular articles of the year: 2018

A collection of the most read articles from the EMBL news website in 2018…

By Josh Tapley

Lab Matters

During cell division, cohesin directly engages DNA (purple) and holds the replicated chromosome together. IMAGE: Nasser Rusan/National Institutes of Health

Cohesin: a glue for DNA

EMBL scientists discover how a component of the cohesin ring binds DNA…

By Patrick Mueller

Science

New EMBL group leader Simone Köhler.

Welcome: Simone Köhler

Which of our genes will be passed on to our children? Simone Köhler wants to find out…

By Emma Steer

Science

In this image of developing cells, fluorescent molecules reveal DNA (blue), part of the X chromosomes (red), and the Xist RNA (white). The green colour shows a region of the cells’ nuclei called the nuclear lamina. IMAGE: Mikael Attia and Edith Heard/Institut Curie

The scientific origins of Edith Heard

EMBL’s next Director General reflects on the questions that drive her research…

By Guest author(s)

Science

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