The new heroics of RNA in cell differentiation
Science EMBL research with Enolase 1 (ENO1) points to a possible new way to understand RNA’s leading role in how cells develop.
2022
science
Judith Zaugg from EMBL Heidelberg receives ERC Consolidator Grant
Lab Matters Judith Zaugg, Group Leader at EMBL Heidelberg, has been awarded an ERC Consolidator Grant of €2 million funded under the European Union’s Horizon Europe research and innovation programme. Over the next five years, the grant will enable her group to study cellular interactions in the human bone…
2022
lab-matters
All heart
Alumni A community of scientists is looking at the estimated three billion heart muscle cells in a human heart to better understand heart disease.
2021
alumni
Induced pluripotent stem cells reveal causes of disease
Science Scientists in the Stegle group and colleagues have studied induced pluripotent stem cells from around 1,000 donors to identify correlations between individual genetic variants and altered gene expression. They linked more than 4,000 of the genetic variants responsible for altered expression…
2021
science
Scratching the surface on cell differentiation
Science Scientists in the Diz-Muñoz group at EMBL Heidelberg are working to build understanding of the role that mechanical properties play in affecting cell behaviour – a young and rapidly developing field of study. They have developed and successfully used a highly specialised technique to manipulate…
2020
science
From stem cells to neurons
Science Scientists at EMBL Heidelberg have investigated stem cells and how they differentiate to become neurons. Their approach included an assessment of the complex interplay of molecules during the differentiation process and generated fundamental new insights into the role of a protein called Sox2 in…
2020
science
From cosmetics to blood cells
Picture of the week Morgan Oatley and her colleagues in Christophe Lancrin’s group investigated how haematopoietic stem cells emerge from the endothelium in developing mouse embryos.
2020
picture-of-the-week
Deleting genes to study how germ cells are born
Science How embryonic stem cells develop into the germ line
2018
science
Ageing is visible in the way cells use glucose
Science Researchers from EMBL and Heidelberg University unveil the molecular mechanisms of ageing
2018
science
HipSci: The human stem cell bank
Science Introducing one of the largest collections of high-quality human induced pluripotent stem cells
2017
science
Blood stem cell differentiation is continuous
Science Study by EMBL and DKFZ researchers means origins of myeloid leukaemias may need rethinking
2017
science
Chromatin cartographer
Alumni EMBL alumnus Jop Kind reflects on the questions that led him to this year’s John Kendrew Award
2016
alumni
New EMBL-Hubrecht Institute partnership
Lab Matters EMBL and the Hubrecht Institute signed a 5-year partnership agreement
2016
lab-matters
Forever young
Science How stem cells resist change
2016
science
Unpacking embryonic pluripotency
Science Embryology, genomics and bioinformatics combine to identify factors regulating mammalian pluripotency.
2015
science
A snapshot of stem cell expression
Science Study of mouse embryonic stem cells reveals new genes involved in the stem-cell regulatory network.
2015
science
Major advance in stem cell technology
Science Researchers produce pristine stem cells, which can be precisely changed into clinically relevant cell types.
2014
science
How stem cells make skin
Science Stem cells have a unique ability: when they divide, they can either give rise to more stem cells, or to a variety of specialised cell types. In both mice and humans, a layer of cells at the base of the skin contains stem cells that can develop into the specialised cells in the layers above.…
2009
science
An unexpected way to cause leukaemia
Science Leukaemia – cancer of blood or bone marrow – is caused by mutations that allow defective blood cells to accumulate and displace healthy blood. To devise effective therapies it is crucial to know which mutations cause leukaemia and which cell type gives rise to leukaemic cells. Researchers from…
2008
science
A matter of force
Science When a cell divides, normally the result is two identical daughter cells. In some cases however, cell division leads to two cells with different properties. This is called asymmetric cell division and plays an important role in embryonic development and the self-renewal of stem cells. Researchers…
2007
science
A new link between stem cells and tumors
Science Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg and the Institute of Biomedical Research of the Parc Científic de Barcelona (IRB-PCB) have now added key evidence to claims that some types of cancer originate with defects in stem cells. The study, reported this week in…
2005
science
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