müller Archives

9 December 2021 Colourful interwoven coils are displayed against a grid of small black and white photographic images.

A gallery of human RNA polymerases

Science, Science & Technology New structural biology research provides fundamental information critical to understanding enzyme mutations connected to rare diseases and cancers.

2021

sciencescience-technology

6 July 2021 Photo of a building with blue sky in the background

New life science Imaging Centre preparing for user access

Connections, Lab Matters The EMBL Imaging Centre is preparing for external user access, after an on-time and on-budget build and handover to the science team.

2021

connectionslab-matters

8 February 2021 Illustration of a laboratory flask to the left of a microscope against an orange/grey background with a zoomed-in cut-out of the microscope view, which is colourful molecules.

Illustration of a laboratory flask to the left of a microscope against an orange/grey background with a zoomed-in cut-out of the microscope view, which is colourful molecules.

A better look at a human RNA polymerase

Science, Science & Technology New EMBL research shows where & to what degree a component of cellular machinery known as RNA Pol III is mutated and becomes problematic.

2021

sciencescience-technology

17 April 2020

Supporting international research on the structure of the coronavirus

Connections, Science EMBL Heidelberg reopens the Cryo-Electron Microscopy Service Platform to support coronavirus structural biology research.

2020

connectionsscience

11 July 2019 Structure of the Elongator complex

A tRNA modifier at work

Science, Science & Technology Using cryo-EM, scientists have determined the structure of a large protein complex called Elongator.

2019

sciencescience-technology

24 October 2018 Insulin receptor structural biology. IMAGE: Felix Weis and Christoph Müller / EMBL

More effective insulin thanks to first 3D image

Science, Science & Technology New study reveals how to make therapeutic insulins more effective than they currently are

2018

sciencescience-technology

17 January 2018 With help from an external transcription factor (lavender, peach, and green), Pol III (grey) and its built-in transcription factor (yellow), create a cage around a cell’s DNA (plum). IMAGE: EMBL/Matthias Vorländer

With help from an external transcription factor (lavender, peach, and green), Pol III (grey) and its built-in transcription factor (yellow), create a cage around a cell’s DNA (plum). IMAGE: EMBL/Matthias Vorländer

Pol III enzyme grips DNA and begins reading fast

Science, Science & Technology EMBL researchers uncover how a key enzyme that helps cells make new proteins starts its work

2018

sciencescience-technology

17 November 2016

New insights into RNA Polymerase I

Science, Science & Technology Cryo EM reconstruction of RNA Polymerase I reveals details of how molecule binds and transcribes DNA

2016

sciencescience-technology

30 August 2016 Data by Natalia Wesolowska has been visualised in 3D stereoscopic view, as an anaglyph and a 3D lenticular poster by Stefan Günther & Gustavo de Medeiros at EMBL

Data by Natalia Wesolowska has been visualised in 3D stereoscopic view, as an anaglyph and a 3D lenticular poster by Stefan Günther & Gustavo de Medeiros at EMBL

See data in a new light

Science, Science & Technology 3D printing, gaming, virtual reality and lenticular posters bring new perspectives to research

2016

sciencescience-technology

2 May 2010 These microscopy images show the region of the embryo larva that will develop into the adult fruit fly’s wing. In cells genetically manipulated so that PR-DUB cannot remove the gene-silencing tag (left), a gene which would normally be silenced becomes turned on (red) - a situation which is corrected when PR-DUB’s activity is restored (right). Image credits: J.Mueller/EMBL.

These microscopy images show the region of the embryo larva that will develop into the adult fruit fly’s wing. In cells genetically manipulated so that PR-DUB cannot remove the gene-silencing tag (left), a gene which would normally be silenced becomes turned on (red) - a situation which is corrected when PR-DUB’s activity is restored (right). Image credits: J.Mueller/EMBL.

Tags on, tags off

Science During embryonic development, proteins called Polycomb group complexes turn genes off when and where their activity must not be present, preventing specialised tissues and organs from forming in the wrong places. They also play an important role in processes like stem cell differentiation and…

2010

science

28 May 2009

Sugarcoating fruit fly development

Science Proteins are the executive agents that carry out all processes in a cell. Their activity is controlled and modified with the help of small chemical tags that can be dynamically added to and removed from the protein. 25 years after its first discovery, researchers at the European Molecular Biology…

2009

science

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Tag:

müller

A gallery of human RNA polymerases

New life science Imaging Centre preparing for user access

A better look at a human RNA polymerase

Supporting international research on the structure of the coronavirus

A tRNA modifier at work

More effective insulin thanks to first 3D image

Pol III enzyme grips DNA and begins reading fast

New insights into RNA Polymerase I

See data in a new light

Tags on, tags off

Sugarcoating fruit fly development

EMBLetc.

Issue 101 Winter 2023

Awards and honours (Issue 101)

Advocating for a generalist approach to science and life

Impact of access to imaging technologies on scientific achievements

Tag:

müller

EMBLetc.

Issue 101 Winter 2023

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