Epigenetics
Unravelling epigenetic reprogramming
A study conducted by the Hackett group at EMBL Rome has identified key factors controlling the complex system of gene regulation during early embryo development, shedding new light on the mechanisms behind these events and on their evolutionary implications. Their findings are published in Nature…
Silencing the SARS-CoV-2 receptor with epigenetic modifications
EMBL scientists develop a new molecular tool to prevent SARS-CoV-2 infection in mice. This tool is able to cause targeted epigenetic modifications of specific genes in specific cell populations. They will use it in mice to target airway cells that express the ACE2 protein – the receptor that…
New insights into epigenetic modifications
Scientists at EMBL Rome unveil the mechanism behind the most studied epigenetic modification.…
EMBL scientists investigate rare lung disease
Researchers in EMBL’s Zaugg group have studied the causes of pulmonary arterial hypertension (PAH), a rare disease that causes high blood pressure in the arteries of the lungs. The study, carried out in collaboration with Stanford University School of Medicine, compared lung cells of patients…
How females shut off their second X chromosome
Scientists provide important new insights into the molecular basis of X-inactivation…
Understanding molecular mechanisms of ageing
Understanding how ageing works at a molecular level…
Wielding the genetic scissors
What CRISPR may bring for the future of biology, and how it is used at EMBL…
Transcription factors controlled by DNA sequence
EMBL scientists gain mechanistic insights into how cellular signalling controls gene regulation…
The scientific origins of Edith Heard
EMBL’s next Director General reflects on the questions that drive her research…
PhD goals: why not start a company?
EMBL-EBI PhD student launches start-up focusing on epigenetics and wellbeing…
