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Epigenetics

epigenetic reprogramming, epigenetic memory, Hackett group

Unravelling epigenetic reprogramming

A study conducted by the Hackett group at EMBL Rome has identified key factors controlling the complex system of gene regulation during early embryo development, shedding new light on the mechanisms behind these events and on their evolutionary implications. Their findings are published in Nature…

By Rossana De Lorenzi

Science

Scientists in the Hackett group at EMBL Rome doing lab work

Silencing the SARS-CoV-2 receptor with epigenetic modifications

EMBL scientists develop a new molecular tool to prevent SARS-CoV-2 infection in mice. This tool is able to cause targeted epigenetic modifications of specific genes in specific cell populations. They will use it in mice to target airway cells that express the ACE2 protein – the receptor that…

By Rossana De Lorenzi

Science

New insights into epigenetic modifications

Scientists at EMBL Rome unveil the mechanism behind the most studied epigenetic modification.…

By Rossana De Lorenzi

Science

EMBL scientists investigate rare lung disease

Researchers in EMBL’s Zaugg group have studied the causes of pulmonary arterial hypertension (PAH), a rare disease that causes high blood pressure in the arteries of the lungs. The study, carried out in collaboration with Stanford University School of Medicine, compared lung cells of patients…

By Fabian Oswald

Science

SPEN protein (green) in living cells. Credit: François Dossin

How females shut off their second X chromosome

Scientists provide important new insights into the molecular basis of X-inactivation…

By Mehdi Khadraoui

Science

Martin-Herranz-Epigenetics

Understanding molecular mechanisms of ageing

Understanding how ageing works at a molecular level…

By Oana Stroe

Science

A model of CRISPR/Cas9

Wielding the genetic scissors

What CRISPR may bring for the future of biology, and how it is used at EMBL…

By Fabian Oswald

Science

How cellular signalling controls chromatin modification. IMAGE: Aleksandra Krolik/EMBL

Transcription factors controlled by DNA sequence

EMBL scientists gain mechanistic insights into how cellular signalling controls gene regulation…

By Patrick Mueller

Science

In this image of developing cells, fluorescent molecules reveal DNA (blue), part of the X chromosomes (red), and the Xist RNA (white). The green colour shows a region of the cells’ nuclei called the nuclear lamina. IMAGE: Mikael Attia and Edith Heard/Institut Curie

The scientific origins of Edith Heard

EMBL’s next Director General reflects on the questions that drive her research…

By Guest author(s)

Science

Daniel Elias Martin Herranz EMBL-EBI

PhD goals: why not start a company?

EMBL-EBI PhD student launches start-up focusing on epigenetics and wellbeing…

By Oana Stroe

Lab Matters

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