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enzyme

HiGlass (http://higlass.io) is an exploratory visualization tool for genomic data developed by Nils Gehlenborg and his team that provides analysts with a flexible interface to explore genomic and epigenomic data, including genome wide interactions, across multiple scales. IMAGE: Nils Gehlenborg

Kendrew and Philipson Awards Winners 2018

EMBL recognises the outstanding work of alumni with the John Kendrew and Lennart Philipson…

By Berta Carreño

Alumni

With help from an external transcription factor (lavender, peach, and green), Pol III (grey) and its built-in transcription factor (yellow), create a cage around a cell’s DNA (plum). IMAGE: EMBL/Matthias Vorländer

Pol III enzyme grips DNA and begins reading fast

EMBL researchers uncover how a key enzyme that helps cells make new proteins starts its…

By Sarah B. Puschmann

Science

In this representation of influenza polymerase, a molecule (white) that strongly inhibits the enzyme’s activity is shown bound to the region of the enzyme (red) that usually binds the cap section of mRNA. IMAGE: EMBL/Cusack Group

Futures: Unravelling influenza

ERC grantee Stephen Cusack shares his vision for the next ten…

By Edward Dadswell

Science

Superimposable structures of the active sites of human DNA polymerase and of a bacterial ribozyme

Enzymes’ superimposable structures revealed

EMBL scientists superimpose structures of two-metal-ion enzymes and reveal new potential drug…

By Berta Carreño

Science

Futures: Phosphatases

ERC grantee Maja Köhn shares her vision for the next ten…

By Edward Dadswell

Science

Enzyme Portal relaunched

Enzyme research made easier

Enzyme Portal makes it easier to explore all enzyme-related data in EMBL-EBI’s public…

By Mary Todd Bergman

Science

3D structure of Mycobacterium tuberculosis’ enzyme PriA

Two in one

In a paper published online today in PNAS, scientists from the European Molecular Biology Laboratory (EMBL) in Hamburg, Germany, reveal new insights…

By Guest author(s)

Science

Raising the alarm when DNA goes bad

Our genome is constantly under attack from things like UV light and toxins, which can damage or even break DNA strands and ultimately lead to cancer…

By Guest author(s)

Science

Sugarcoating fruit fly development

Proteins are the executive agents that carry out all processes in a cell. Their activity is controlled and modified with the help of small chemical…

By Guest author(s)

Science

High resolution image of the key domain of the influenza virus polymerase. The active site responsible for RNA cleavage is shown in red. Its activity is crucial for the virus to multiply in human cells

New findings reveal how influenza virus hijacks human cells

Influenza is and remains a disease to reckon with. Seasonal epidemics around the world kill several hundred thousand people every year. In the light…

By Guest author(s)

Science

X chromosome exposed

Researchers from the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, and the EMBL-European Bioinformatics Institute (EMBL-EBI)…

By Guest author(s)

Science

Researchers shed light on shrinking of chromosomes

A human cell contains an enormous 1.8 metres of DNA partitioned into 46 chromosomes. These have to be copied and distributed equally into two…

By Guest author(s)

Science

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