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HiGlass (http://higlass.io) is an exploratory visualization tool for genomic data developed by Nils Gehlenborg and his team that provides analysts with a flexible interface to explore genomic and epigenomic data, including genome wide interactions, across multiple scales. IMAGE: Nils Gehlenborg

Kendrew and Philipson Awards Winners 2018

EMBL recognises the outstanding work of alumni with the John Kendrew and Lennart Philipson Awards…

By Berta Carreño

Alumni

With help from an external transcription factor (lavender, peach, and green), Pol III (grey) and its built-in transcription factor (yellow), create a cage around a cell’s DNA (plum). IMAGE: EMBL/Matthias Vorländer

Pol III enzyme grips DNA and begins reading fast

EMBL researchers uncover how a key enzyme that helps cells make new proteins starts its work…

By Sarah B. Puschmann

Science

In this representation of influenza polymerase, a molecule (white) that strongly inhibits the enzyme’s activity is shown bound to the region of the enzyme (red) that usually binds the cap section of mRNA. IMAGE: EMBL/Cusack Group

Futures: Unravelling influenza

ERC grantee Stephen Cusack shares his vision for the next ten years…

By Edward Dadswell

Science

Superimposable structures of the active sites of human DNA polymerase and of a bacterial ribozyme

Enzymes’ superimposable structures revealed

EMBL scientists superimpose structures of two-metal-ion enzymes and reveal new potential drug targets…

By Berta Carreño

Science

Futures: Phosphatases

ERC grantee Maja Köhn shares her vision for the next ten years…

By Edward Dadswell

Science

Enzyme Portal relaunched

Enzyme research made easier

Enzyme Portal makes it easier to explore all enzyme-related data in EMBL-EBI’s public resources.…

By Mary Todd Bergman

Science

3D structure of Mycobacterium tuberculosis’ enzyme PriA

Two in one

In a paper published online today in PNAS, scientists from the European Molecular Biology Laboratory (EMBL) in Hamburg, Germany, reveal new insights into the workings of enzymes from a group of bacteria including Mycobacterium tuberculosis, the bacterium that causes tuberculosis. The new findings…

By Guest author(s)

Science

A link between our body’s energy levels and a protein that wraps our DNA?

Living organisms need to sense the amount of energy that is available to them and regulate the activity of their genes accordingly. Scientists have made the unexpected finding that a histone protein, which wraps DNA into tight bundles and regulates gene activity, can bind a small molecule produced…

By Guest author(s)

Science

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