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cryo-electron tomography

Black-and-white sphere with coronavirus spike protein structures and a two-layered ring of virus membrane superimposed.

Variations on a spike

What does coronavirus’s spike protein look like in 3D? EMBL scientists and colleagues used cryo-electron tomography and molecular dynamics…

By Marius Bruer

Picture of the week
Greyscale image of a cell with its internal components visible

Seeing through a cell

Liang Xue used cryo-electron tomography to capture this detailed image of a Mycoplasma pneumoniae…

By Mathias Jäger

Picture of the week
This visual representation shows the newly identified architecture (left) of the coupled molecular machines responsible for transcription (green; DNA in magenta) and translation (blue and yellow), accompanied by the protein interaction network from mass spectrometry (centre) and the cryo-electron tomography data (right) from Mycoplasma pneumoniae that was used to model the structure. Credit: Liang Xue and Julia Mahamid/EMBL

Visualising the cell’s molecular machinery in action

A new approach that allows researchers to see molecular machinery at work inside cells has offered a deeper understanding of how bacteria produce…

By Ivy Kupec

Science

Supporting international research on the structure of the coronavirus

EMBL Heidelberg reopens the Cryo-Electron Microscopy Service Platform to support coronavirus structural biology…

By Anne-Marie Alleaume

Science
Cryo-ET and micropatterning

Photo-micropatterning advances structural cell biology

A new technique in…

By Cella Carr

Science
The retromer complex

Solving the structure of retromer

Retromer’s 3D structure improves understanding of cellular sorting and…

By Guest author(s)

Science
Lattice maps for immature HIV particles. The 3D computer reconstruction shows the immature Gag lattice of HIV that matures to form the protein shell of the infecious virus. Maps are shown in perspective such that hexamers on the rear surface of the particle appear smaller. The side of the particle toward the viewer lacks ordered Gag. IMAGE: John Briggs/EMBL

New electron microscopy images reveal the assembly of HIV

Scientists at the European Molecular Biology Laboratory (EMBL) and the University Clinic Heidelberg, Germany, have produced a three-dimensional…

By Guest author(s)

Science

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