AlphaFold Database welcomes community datasets
Latest AlphaFold Database update adds high-value datasets for microbial and viral proteins, generated by specialist communities
2026
updates-from-data-resources
AI in Science Summit: Europe charts a new course for AI-powered discovery
EMBL joined European partners at AIS25 to explore how AI can advance life-science research and support Europe’s emerging strategy for AI in science.
CONNECTIONS2025
connections
AlphaFold Database launches custom annotations feature
The AlphaFold Database (AlphaFold DB) has introduced a new functionality that enables users to integrate and visualise custom sequence annotations. These annotations are processed in the browser for the current session only. The new functionality is made possible through the integration of the PDBe…
2025
updates-from-data-resources
EMBL-EBI and Google DeepMind renew partnership and release update to AlphaFold Database
Deeper collaboration between EMBL-EBI and Google DeepMind brings updates to the AlphaFold Database.
SCIENCE & TECHNOLOGY2025
science-technologytechnology-and-innovation
New AlphaFold Database entry pages
The AlphaFold Protein Structure Database (AFDB) has redesigned its entry pages to make exploring predicted protein structures faster, clearer, and more intuitive. This update delivers a streamlined experience across devices, whether you’re browsing from the lab, your desktop, or on the move.…
2025
updates-from-data-resources
Quality and function at a glance: The role of TED in the AlphaFold Database
The AlphaFold Protein Structure Database (AFDB) now integrates The Encyclopedia of Domains (TED), a resource designed to systematically identify and classify structural domains within AlphaFold-predicted protein structures. TED provides domain boundaries for 365 million domains across more than one…
2025
updates-from-data-resources
We are EMBL: Francesco Costa on protein design and the EMBL PhD programme
Francesco talks about his work in protein science, fascination for protein design, and how he's finding the EMBL International PhD programme.
PEOPLE & PERSPECTIVES2025
people-perspectivesperspectives
Sparking a data revolution
The introduction of computational methods in biology opened up an entirely new world of insights and breakthroughs. Over the last several decades, EMBL has been at the forefront of discoveries and innovations that have not only propelled the field forward but also opened up access to bioinformatics…
SCIENCE & TECHNOLOGY2024
science-technology
Computational protein design and protein structure prediction win Nobel Prize in Chemistry
Creators of AI system AlphaFold receive 2024 Nobel Prize for Chemistry.
SCIENCE & TECHNOLOGY2024
sciencescience-technology
Machine learning discoveries honoured with 2024 Nobel Prize for Physics
The prize was awarded to John J. Hopfield, Princeton University, USA, and Geoffrey Hinton, University of Toronto, Canada, for their seminal contributions to the foundational methods that enabled the development of machine learning.
SCIENCE & TECHNOLOGY2024
science-technology
EMBL-EBI’s open data resources for biodiversity and climate research
EMBL-EBI data resources help advance biodiversity and climate change research by enabling scientists to study species interactions, evolutionary processes, ecosystem health, and more.
SCIENCE & TECHNOLOGY2024
science-technologytechnology-and-innovation
AlphaFold database empowers researchers with enhanced structural search via Foldseek integration
Traditional sequence search methods are fast and efficient but rely solely on comparing amino acid sequences. This approach can miss crucial insights because proteins with similar functions can have vastly different sequences. Although their sequences have diverged, these proteins often retain 3D…
2024
updates-from-data-resources
We are EMBL: Melanie Schneider on changing career trajectory
ARISE fellow Melanie Schneider shares how she uncovered a new interest in research infrastructures and supporting discovery.
PEOPLE & PERSPECTIVES2024
people-perspectivesperspectives
AI approaches in structural biology and drug discovery
EMBL Grenoble and the ESRF hosted a workshop bringing together representatives from research and industry to discuss the ever-growing role of artificial intelligence in the field of structural biology.
CONNECTIONS2024
connections
AlphaMissense data integrated into Ensembl, UniProt, DECIPHER and AlphaFold DB
The integration enables researchers to easily access AI-generated scores estimating how likely genetic variants are to be pathogenic
2024
technology-and-innovation
When AI meets biology
A recent EMBO | EMBL conference provided a forum for researchers to share how AI is making a difference in biology and bioinformatics.
SCIENCE & TECHNOLOGY2024
science-technology
RNA to rule them all
The Kosinski Group at EMBL Hamburg collaborated with other groups in Hamburg to reveal critical steps in Lassa virus ribonucleoparticle assembly and recruitment, and the crucial role played by RNA in in the Lassa virus life cycle.
SCIENCE & TECHNOLOGY2023
sciencescience-technology
EMBL receives German AI prize
EMBL receives the German AI prize awarded for outstanding services to the research and development as well as application and commercialisation of artificial intelligence (AI) in life science research.
EMBL ANNOUNCEMENTS2023
embl-announcementsscience
New predictions of genetic variant pathogenicity using AlphaFold protein structures
Ensembl Variant Effect Predictor integrates Google DeepMind’s new AlphaMissense Database for better predictions of genetic variant pathogenicity.
SCIENCE & TECHNOLOGY2023
science-technologytechnology-and-innovation
Revealing the secrets of protein evolution using the AlphaFold database
Researchers use the AlphaFold database and Foldseek Cluster algorithm to analyse millions of predicted protein structures and offer new insights into protein evolution.
SCIENCE & TECHNOLOGY2023
research-highlightssciencescience-technology
Major user experience update in AlphaFold Database
The AlphaFold Database boasts improved user experience, including better search filters and an improved 3D viewer.
2023
updates-from-data-resources
Janet Thornton retires: a pioneer in structural bioinformatics
In recognition of Janet Thornton’s retirement, we look back at some of her biggest accomplishments shaping the field of bioinformatics.
LAB MATTERSPEOPLE & PERSPECTIVES2023
announcementslab-matterspeople-perspectives
WormBase ParaSite 18 released
WormBase ParaSite release 18 adds largest number of new genomes and annotations since launch, as well as full integration with AlphaFold.
SCIENCE & TECHNOLOGY2023
science-technologyupdates-from-data-resources
Case study: AlphaFold uses open data and AI to discover the 3D protein universe
Open data played a pivotal role in the development of the AlphaFold AI. The same open principles now apply to AlphaFold predictions.
2023
perspectivesscience
AlphaFold applications – a community assessment
Researchers use social media to share findings on how useful AlphaFold predictions are for different applications.
2022
research-highlightsscience
AlphaFold developers and EMBL alumnus among Breakthrough Prize recipients
Cell biologist Anthony Hyman and DeepMind’s Demis Hassabis and John Jumper were announced among 25 Breakthrough Prize recipients
EMBL ANNOUNCEMENTSLAB MATTERS2022
embl-announcementslab-matters
AlphaFold: where will the next AI breakthrough come from?
Ewan Birney, Deputy Director General of EMBL and Director of EMBL-EBI, reveals the key factors that enabled AlphaFold to change the world of biology.
PEOPLE & PERSPECTIVES2022
people-perspectivesperspectivesscience
AlphaFold predicts structure of almost every catalogued protein known to science
AlphaFold database offers a look at 3D protein universe.
SCIENCE & TECHNOLOGY2022
sciencescience-technologytechnology-and-innovation
Puzzling out the structure of a molecular giant
Scientists have solved several mysteries around the structure and function of a true molecular giant: the human nuclear pore complex. They created the most complete model of the complex thanks to combining the program AlphaFold2 with cryo-electron tomography, integrative modelling, molecular…
SCIENCE & TECHNOLOGY2022
sciencescience-technology
Predicted complexes from ModelArchive now on PDBe-KB pages
New dataset of predicted protein complexes accessible through 3D-Beacons Network.
2022
updates-from-data-resources
Learning from Deep Learning: the inspirational story behind AlphaFold
DeepMind visits EMBL Heidelberg to discuss current and future implications of Artificial Intelligence for life science research.
SCIENCE & TECHNOLOGY2022
sciencescience-technology
AlphaFold update – neglected tropical diseases
Latest AlphaFold database update adds 27 new organisms and almost 200,000 new protein structure predictions relevant to neglected tropical diseases and antimicrobial resistance
2022
updates-from-data-resources
Artificial intelligence — a scientific game changer in 2021
The systematic application of AI in life sciences as in the AlphaFold algorithm for predicting protein structures has been named '2021 Breakthrough of the Year' by Science magazine.
SCIENCE & TECHNOLOGY2021
sciencescience-technology
DeepMind and EMBL release the most complete database of predicted 3D structures of human proteins
Partners use AlphaFold, the AI system recognised last year as a solution to the protein structure prediction problem, to release more than 350,000 protein structure predictions including the entire human proteome to the scientific community.
SCIENCE & TECHNOLOGY2021
sciencescience-technology
Accessible 3D protein models to accelerate scientific discovery
DeepMind and EMBL-EBI to make millions of protein structure predictions freely available to the scientific community.
SCIENCE & TECHNOLOGY2021
sciencescience-technology
Great expectations – the potential impacts of AlphaFold DB
A discussion of the applications that AlphaFold DB may enable and the possible impact of the resource on science and society.
SCIENCE & TECHNOLOGY2021
sciencescience-technology
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