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2007

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14 July 2022 Visualising the ocean below and above surface, showing several species and giving written details on the ocean microbiome composition

Priorities for ocean microbiome research

Science Microbial communities play essential roles in ocean ecology and planetary health. A recent publication highlights priorities for understanding and protecting ocean microbiomes.

2022

science

17 December 2007

An ambulance man for muscle damage

Science It does not take much to injure a muscle. Sometimes one sudden, inconsiderate movement does the job. Unfortunately, damaged muscles are not as efficient at repair as other tissues such as bone. Researchers of the European Molecular Biology Laboratory’s Mouse Biology Unit (EMBL), Italy, and…

2007

science

11 December 2007

ArrayExpress database doubles in size to 100,000 hybridisations

Lab Matters ArrayExpress, the publicly available database of transcriptomics data at the European Molecular Biology Laboratory’s European Bioinformatics Institute (EMBL-EBI), has doubled in size in 2007, reaching the 100,000-hybridisation milestone. The database now holds snapshots of gene expression…

2007

lab-matters

5 December 2007

The closest look ever at native human tissue

Science Seeing proteins in their natural environment and interactions inside cells has been a longstanding goal. Using an advanced microscopy technique called cryo-electron tomography, researchers from the European Molecular Biology Laboratory (EMBL) have visualised proteins responsible for cell-cell…

2007

science

2 December 2007

How cells keep in shape

Science Cells in our body come in various shapes and sizes. Each cell is shaped in such a way as to optimise it for a specific function. When things go wrong and a cell does not adopt its dedicated shape, its function can be impaired and the cell can cause problems in the body. Researchers at […]

2007

science

12 November 2007

Luxembourg joins EMBL

Lab Matters Today, the European Molecular Biology Laboratory (EMBL) announces Luxembourg as the new member of its international community. Accepted by EMBL’s council and ratified by the parliament of Luxembourg, the Grand-Duchy has officially joined the institute as the 20th member state. “EMBL is…

2007

lab-matters

23 October 2007

The East Wing and a new dawn for the EMBL-EBI

Lab Matters The European Molecular Biology Laboratory’s European Bioinformatics Institute (EMBL-EBI) officially opens its new East Wing today with a reception for prominent guests. The East Wing will be jointly opened by Ian Pearson, Minister of State for Science and Innovation, UK, and Robert-Jan Smits,…

2007

lab-matters

21 October 2007

Scientists uncover how hormones achieve their effects

Science New insights into the cellular signal chain through which pheromones stimulate mating in yeast have been gained by scientists at the European Molecular Biology Laboratory [EMBL]. Similar signal chains are found in humans, where they are involved in many important processes such as the…

2007

science

3 October 2007

EMBL reaches north

Lab Matters Today the European Molecular Biology Laboratory (EMBL), the University of Helsinki, Finland, the University of Oslo, Norway, and Umeå University, Sweden, officially launch their new Nordic EMBL Partnership for Molecular Medicine. The agreement will encourage scientific exchange and collaborations…

2007

lab-matters

15 September 2007

A molecule that protects from neuronal disorders

Science Many neuronal disorders, including epilepsy, schizophrenia and lissencephaly ─ a form of mental retardation ─ result from abnormal migration of nerve cells during the development of the brain. Researchers from the Mouse Biology Unit of the European Molecular Biology Laboratory (EMBL) in Italy,…

2007

science

28 August 2007

Minimum Information Standards ─ all for one and one for all

Lab Matters Three papers published by EMBL scientists and their collaborators will make it much easier to share and compare information from large-scale proteomics data. The papers are published in Nature Biotechnology on 8 and 26 August. As the quantity of available biological information and the use of…

2007

lab-matters

9 August 2007

A unique arrangement for egg cell division

Science Which genes are passed on from mother to child is decided very early on during the maturation of the egg cell in the ovary. In a cell division process that is unique to egg cells, half of the chromosomes are eliminated from the egg before it is fertilised. Using a powerful microscope, researchers…

2007

science

30 July 2007

Uncovering the secrets of the deep

Science The UniProt Consortium, which includes the European Molecular Biology Laboratory’s European Bioinformatics Institute (EMBL-EBI), has added a new database repository for metagenomic and environmental data to its family of protein sequence databases. Metagenomics is the large-scale genomic…

2007

science

11 July 2007

EMBL expands to Australia

Lab Matters Today, delegates representing the 19 member states of the European Molecular Biology Laboratory (EMBL) offered Australia associate membership in EMBL’s international community. The membership is planned to start officially in January 2008 and will initially last for seven years. “EMBL…

2007

lab-matters

9 July 2007

A stepwise retreat: how immune cells catch pathogens

Science To protect us from disease our immune system employs macrophages, cells that roam our body in search of disease-causing bacteria. With the help of long tentacle-like protrusions, macrophages can catch suspicious particles, pull them towards their cell bodies, internalise and destroy them. Using a…

2007

science

8 July 2007

A gene that protects from kidney disease

Science Researchers from the European Molecular Biology Laboratory (EMBL) and the University of Michigan have discovered a gene that protects us against a serious kidney disease. In the current online issue of Nature Genetics they report that mutations in the gene cause nephronopthisis (NPHP) in humans and…

2007

science

29 June 2007

Modern brains have an ancient core

Science Hormones control growth, metabolism, reproduction and many other important biological processes. In humans, and all other vertebrates, the chemical signals are produced by specialised brain centres such as the hypothalamus and secreted into the blood stream that distributes them around the body.…

2007

science

22 June 2007

New compound effectively treats fungal infections

Science A new mechanism to attack hard-to-treat fungal infections has been revealed by scientists from the biotech company Anacor Pharmaceuticals Inc., California, and the European Molecular Biology Laboratory [EMBL] outstation in Grenoble, France. In the current issue of Science they describe…

2007

science

15 June 2007

Casting the molecular net

Science Scientists at the Samuel Lunenfeld Research Institute of Mount Sinai Hospital (Canada), the European Molecular Biology Laboratory (Germany), and Massachusetts Institute of Technology (USA) have created a new computational method called NetworKIN. This method uses biological networks to better…

2007

science

14 June 2007

New findings challenge established views about human genome

Science The ENCyclopedia Of DNA Elements (ENCODE), an international research consortium organised by the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health (NIH), today published the results of its exhaustive, four-year effort to build a “parts list” of…

2007

science

10 June 2007

Researchers shed light on shrinking of chromosomes

Science A human cell contains an enormous 1.8 metres of DNA partitioned into 46 chromosomes. These have to be copied and distributed equally into two daughter cells at every division. Condensation, the shortening of chromosomes, allows the cell to handle such huge amounts of genetic material during cell…

2007

science

5 June 2007

Uncovering the molecular basis of obesity

Science Why does the same diet make some of us gain more weight than others? The answer could be a molecule called Bsx, as scientists from the European Molecular Biology Laboratory (EMBL), the German Institute for Nutrition (DIFE), Potsdam, and the University of Cincinnati report in the current issue of…

2007

science

3 June 2007

New insights into the neural basis of anxiety

Science People who suffer from anxiety tend to interpret ambiguous situations, situations that could potentially be dangerous but not necessarily so, as threatening. Researchers from the Mouse Biology Unit of the European Molecular Biology Laboratory (EMBL) in Italy have now uncovered the neural basis for…

2007

science

22 May 2007

The first public nucleotide sequence database turns 25

Lab Matters It was the world’s earliest public database of DNA and RNA sequences and remains Europe’s primary nucleotide sequence resource. The database is maintained by EMBL’s European Bioinformatics Institute in Hinxton (UK) in collaboration with its US and Japanese counterparts GenBank and…

2007

lab-matters

16 May 2007

Mechanism of microRNAs deciphered

Science Over 30% of our genes are under the control of small molecules called microRNAs. They prevent specific genes from being turned into protein and regulate many crucial processes like cell division and development, but how they do so has remained unclear. Now researchers from the European Molecular…

2007

science

4 May 2007

A matter of force

Science When a cell divides, normally the result is two identical daughter cells. In some cases however, cell division leads to two cells with different properties. This is called asymmetric cell division and plays an important role in embryonic development and the self-renewal of stem cells. Researchers…

2007

science

20 April 2007

The origin of the brain lies in a worm

Science The rise of the central nervous system (CNS) in animal evolution has puzzled scientists for centuries. Vertebrates, insects and worms evolved from the same ancestor, but their CNSs are different and were thought to have evolved only after their lineages had split during evolution. Researchers from…

2007

science

14 March 2007

Researchers identify molecular basis of inflammatory bowel disease

Science Inflammatory bowel diseases, such as Crohn’s disease and Ulcerative Colitis, severely impair the lives of more than four million people worldwide. The development of effective therapies against these diseases requires an understanding of their underlying molecular mechanisms. Researchers from…

2007

science

6 March 2007

An architectural plan of the cell

Science Like our body every cell has a skeleton that provides it with a shape, confers rigidity and protects its fragile inner workings. The cytoskeleton is built of long protein filaments that assemble into networks whose overall architecture and fine detail can only be revealed with high resolution…

2007

science

4 March 2007

A clearer view on biology

Science The European Molecular Biology Laboratory (EMBL) has developed a new computational tool that makes images obtained with cutting-edge microscopes even sharper. The technological advance and its applications are published in this week’s online issue of the journal Nature Methods. Since the…

2007

science

25 February 2007

A first glimpse of the influenza replication machine

Science In 1918, 50 million people died during a worldwide influenza pandemic caused by mutation of a bird-specific strain of the influenza virus. Recently H5N1, another highly infectious avian strain has caused outbreaks of bird flu around the world. There is great concern that this virus might also…

2007

science

12 February 2007

A signal that protects the liver from hepatitis and cancer

Science Liver cancer is one of the deadliest cancers worldwide; every year sees more than 400,000 new cases, and most of the victims die in less than one year. Despite extensive research, the underlying molecular mechanisms of the disease are poorly understood. A new study by researchers from the Mouse…

2007

science

11 February 2007

Putting an old drug to a new use

Science We all know that iron deficiencies are dangerous, but also too much iron is bad for our health. Our body stores excess iron in various tissues, where it can lead to organ failure and even death if not treated before irreversible damage has occurred. Researchers from the Innsbruck Medical…

2007

science

2 February 2007

Investigating the invisible life in our environment

Science Microorganisms make up more than a third of the Earth’s biomass. They are found in water, on land and even in our bodies, recycling nutrients, influencing the planet’s climate or causing diseases. Still, we know surprisingly little about the smallest beings that colonise Earth. A new…

2007

science

8 January 2007

UK PubMed Central launched

Lab Matters From today scientists will be able to access a vast collection of biomedical research and to submit their own published results for inclusion in a new online resource. Based on a model currently used by the US National Institute of Health, UK PubMed Central (UKPMC) will provide free access to a…

2007

lab-matters

8 January 2007

Getting to the bottom of memory

Science Phone numbers, the way to work, granny’s birthday – our brain with its finite number of nerve cells can store incredible amounts of information. At the bottom of memory lies a complex network of molecules. To understand how this network brings about one of the most remarkable capacities of…

2007

science

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