Science, Science & Technology Scientists have solved several mysteries around the structure and function of a true molecular giant: the human nuclear pore complex. They created the most complete model of the complex thanks to combining the program AlphaFold2 with cryo-electron tomography, integrative modelling, molecular…
2022
sciencescience-technology
Science, Science & Technology EMBL Hamburg’s Kosinski Group, the Beck Laboratory at the Max Planck Institute of Biophysics, and colleagues at EMBL Heidelberg recorded the nuclear pore complex contracting in living cells. They visualised the movement with an unprecedented level of detail with help of new software called…
2021
sciencescience-technology
Science, Science & Technology A new collaborative study led by EMBL group leaders Kiran Patil, Nassos Typas, and Peer Bork has found that common medications accumulate in human gut bacteria. This process reduces drug effectiveness and affects the metabolism of common gut microbes, thereby altering the gut microbiome.
2021
sciencescience-technology
Picture of the week, Science & Technology What does coronavirus’s spike protein look like in 3D? EMBL scientists and colleagues used cryo-electron tomography and molecular dynamics simulations to find out.
2021
picture-of-the-weekscience-technology
Science, Science & Technology Scientists from the Beck group have studied the 3D structure of nuclear pores in budding yeast. They show how the architecture of the nuclear pore complex differs inside cells compared to its form observed in vitro studies.
2020
sciencescience-technology
Science, Science & Technology EMBL scientists and collaborators help reveal the process by which enormous quantities of DNA are folded into cells.
2020
sciencescience-technology
Science, Science & Technology EMBL scientists have discovered that the proteome is substantially affected by both sex and diet
2019
sciencescience-technology
Science, Science & Technology EMBL scientists reveal NPC architecture of algae
2018
sciencescience-technology
Science, Science & Technology EMBL scientists create a turnover catalogue of almost 10.000 proteins from primary cells
2018
sciencescience-technology
Science, Science & Technology Puzzle of nuclear pore formation in growing nuclei solved
2016
sciencescience-technology
Science, Science & Technology Storage of pre-made nuclear pores allows for rapid cell division in fruit fly embryos
2016
sciencescience-technology
Science, Science & Technology First detailed structural description of all the rings of nuclear pores
2016
sciencescience-technology
Science A nuclear pore riddle: how can you use the same number of pieces to form two rings that fit inside each other?
2015
science
Science Multifaceted approach reveals how brain and liver age, helps explain why ageing brain loses plasticity.
2015
science
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