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An illustration of single-cell RNA sequencing (scRNA-seq)

Enabling functional genomics studies in individual cells

Scientists at EMBL Heidelberg have developed a new method, called Targeted Perturb-seq (TAP-seq), which increases the scale and precision of functional genomics CRISPR–Cas9 screens by orders of magnitude. Their method overcomes limitations in previous applications of single-cell RNA sequencing, and will enable scientists to perform functional genomics experiments on an unprecedented scale.

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Marius Bruer
Science
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This image is a 3D-rendering of the automatic segmentation of a HeLa cell, made by Julian Hennies from the Schwab team at EMBL Heidelberg.

By  Mathias Jäger

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