Head of Genomics Core Facility
GeneCore is the in-house genomics service centre at EMBL equipped with state-of-the-art technologies required for functional genomics analyses and operated by highly-qualified staff.Edit
The Genomics Core Facility (GeneCore) provides its services to a broad range of users ranging from small research groups to international consortia.
Our massively parallel sequencing (MPS) suite boasts Illumina sequencers – NextSeq500, NextSeq2000, and MiSeq. We also work in close collaboration with the University of Heidelberg and the German Cancer Research Center (DKFZ) to further enhance the capabilities of these sequencing technologies.
Preparation of MPS libraries for various applications is supported by a robust instrumentation infrastructure (e.g. Covaris, Bioanalyzer, Agilent Fragment Analyzer, Agilent Femto Pulse, Qubit, and more).
To support processing of large quantities of samples we have employed a suite of liquid handling robots such as the Beckman Coulter i7 and FXp, and Dispendix iDot.
GeneCore provides the following analyses in a single-end or a pair-end sequencing mode, including multiplexing:
GeneCore continues to establish new protocols enabling the processing of challenging samples such as low input or metagenomics samples.
For analysis of MPS data, we work intensively with EMBL’s bioinformatics community on the development of in-house, freely accessible tools.
To date, GeneCore has generated more than 100 terabases of MPS sequence data for its users. GeneCore staff also train individual researchers and organize practical courses on corresponding subjects.
MPS continues to be a very dynamic and rapidly evolving technology. We collaborate with several companies involved in developing MPS-related products, for instance testing them in our workflows. GeneCore is a member of the early-access program of Illumina, Agilent, NEB, Dispendix, and Beckman Coulter.
A detailed overview of the GeneCore activities can be found at www.genecore.embl.de.
Nat Commun 2020
G3: Genes, Genomes, Genetics 2020
Genomics Core Facility
Tel:+49 6221 387- 8486/ -8492