GeneCore is EMBL’s in-house genomics service centre, providing cutting-edge technologies, scientific expertise, and collaborative support to advance genomics research.
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Vladimir Benes

Head of Genomics Core Facility and Scientific Ombudsperson

What do we do?

The EMBL Genomics Core Facility (GeneCore) provides comprehensive support for a wide range of Next-Generation Sequencing (NGS) applications. We assist researchers in processing nucleic acid samples from diverse and often complex biological studies using advanced genomic technologies.

Our goal is to provide a user-focused service environment that combines state-of-the-art sequencing platforms with expert scientific support. We offer high-quality standard NGS services while continuously adopting new methodologies to expand and improve our capabilities.

Through our evolving infrastructure and technical expertise, we ensure that researchers have access to reliable, innovative, and efficient NGS solutions.

Partners

Equipment

Our Team

Illustrated workflow showing how users and GeneCore interact during experiment design, registration, shipment, sample processing, library preparation, sequencing, quality control, data transfer, and data analysis. — GeneCore’s sample workflow

Services we provide

Sequencing:
– NGS. (Next-Generation Sequencing)
– MPS. (Massively Parallel Sequencing)
Experiment design and consultation.
“Walk-In Upon Training” Access to instruments and support. (qPCR instruments, Agilent Bioanalyzer, Tape Station, ONT PromethION, ONT GridION)
Data analysis consulting.
Support for automation and liquid handling robotics projects.

Access Information

Please review the Rules of Access and Sample Instructions before contacting GeneCore. Once you’ve read them, feel free to reach out to us.

External User Access

If you are not EMBL-related user and you want access to one of our services, please check our Rules of Access and Sample Instructions section before.

Internal User Access

If you are an EMB-related user, please check our intranet for important information, also check the Rules of Access and Sample Instructions section before.

Current Applications

Single-cell genomic applications (scRNA-Seq, scDNA-Seq)

Transcriptome sequencing: RNA-Seq.‎ ‎ ‎ ‎ ‎ ‎ ‎ ‎ ‎ ‎

De novo sequencing & re-sequencing of genomic DNA.

Genome-wide chromatin and DNA methylation analysis

Latest Publications and News

Nuclear Ca2+-Calmodulin signaling in cardiac myocytes reduces catecholamine-evoked protein translation and prevents hypertrophy.

Riedel A, Medert R, Monaco S, Gjerga E, Tolksdorf X, Richter C, Malz M, Schrader M, Kuryshev V, Busch M, Jungmann A, Löwenthal Z, Philippaert K, Wirth A, Ottenheijm R, Benes V, Most P, Dieterich C, Völkers M, Bading H, Freichel M

Cell calcium, 2026

doi: 10.1016/j.ceca.2025.103101.

Epigenetic dysregulation of IRF9 drives excessive interferon signaling in COPD.

Llamazares-Prada M, Schwartz U, Pease DF, Pohl ST, Ackesson D, Li R, Behrendt A, Tamas R, Stammler V, Richter M, Muley T, Scherer M, Hey J, Espinet E, Heußel CP, Warth A, Schneider MA, Winter H, Herth FJ, Imbusch CD, Brors B, Benes V, Wyatt D, Jurkowski TP, Stahl HF, Plass C, Jurkowska RZ

EMBO molecular medicine, 2026

doi: 10.1038/s44321-026-00386-9.

Genomic analysis in chemotherapy-naïve prostate cancer prior to PSMA-targeted treatment.

Amghar M, Roscher M, Rausch T, Özgür H, Bauder-Wüst U, Bruchertseifer F, Morgenstern A, Beneš V, Kratochwil C, Benešová-Schäfer M

Frontiers in oncology, 2026

doi: 10.3389/fonc.2026.1741080.

Latest news